Bipolar microfluidic production device

By combining components such as the microfluidic body, chip, blue light tower and low-temperature collector, and utilizing the synergistic effect of electric field and dielectrophoretic force, the problems of temperature control and activity protection are solved, high precision and consistency of fluid processing are achieved, and the processing effect of the bipolar microfluidic device is improved.

CN223366990UActive Publication Date: 2025-09-23JINLIN MEDICAL COLLEGE
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Patent Information

Application Number
CN202521530188.0
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-07-22
Publication Date
2025-09-23
Estimated Expiration
2035-07-22

AI Technical Summary

Technical Problem

Existing bipolar microfluidic devices have difficulty accurately controlling fluid temperature, resulting in reduced sample activity and decreased reaction efficiency. At the same time, insufficient protective measures affect the accuracy and reliability of processing results.

Method used

A combination of microfluidic body, chip, blue light tower, cryogenic collector and thermostat is adopted to manipulate fluids through the synergistic effect of electric field, electroosmotic flow and dielectrophoretic force. The temperature is precisely controlled by insulating sleeve and thermostat, and the blue light tower and cryogenic collector are combined to protect the fluid activity and chemical stability.

Benefits of technology

It achieves high-precision manipulation of fluid processing and precise temperature control, improves processing speed and effect, forms a coherent automated process, and improves the accuracy and consistency of fluid processing.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the field of bipolar microfluidics, and discloses a bipolar microfluidics production device which comprises a bearing table, a microfluidics main body is fixedly arranged on the upper surface of the bearing table, a chip is fixedly arranged on the upper surface of the bearing table, and a blue light tower is fixedly arranged on the upper surface of the bearing table. According to the device, through the arrangement of the micro-fluidic main body, primary fluid treatment can be carried out on liquid, through the arrangement of the chip, high-precision control can be carried out on small particles and cells in the fluid through the synergistic effect of an electric field generated by the bipolar electrode, electroosmotic flow and dielectrophoretic force, and through the arrangement of the heat preservation sleeve and the temperature adjusting instrument, high-precision control can be carried out on the small particles and cells in the fluid. The temperature of the fluid in transmission can be accurately controlled, the fluid can be specifically treated through the arrangement of a blue light tower, the activity of a biological sample and the stability of chemical substances in the fluid can be effectively protected through the arrangement of a low-temperature collector, and the fluid can be uniformly treated through the arrangement of a blue light emission vessel and a rotor.
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Description

Technical Field

[0001] The utility model relates to the field of bipolar microfluidics, in particular to a bipolar microfluidics production device. Background Art

[0002] Bipolar microfluidics is a technology that uses bipolar electrodes to achieve fluid manipulation in microfluidic chips. Bipolar microfluidic chips achieve precise manipulation of tiny particles and cells through the synergistic effects of electric fields, electroosmotic flow, and dielectrophoretic forces.

[0003] However, when processing fluids, current bipolar microfluidic devices have difficulty accurately controlling the fluid temperature during transmission, which will lead to reduced sample activity and reaction efficiency. In addition, after the fluid is processed, the protection measures for sample activity and chemical stability are poor, thus affecting the accuracy and reliability of the processing results. Therefore, we propose a bipolar microfluidic production device to solve the above problems. Utility Model Content

[0004] The purpose of the present invention is to provide a bipolar microfluidic production device to solve the problems raised in the above background technology.

[0005] To achieve the above objectives, the present invention provides the following technical solutions:

[0006] A bipolar microfluidic production device includes a carrier platform, a microfluidic body is fixedly installed on the upper surface of the carrier platform, a chip is fixedly installed on the upper surface of the carrier platform, a blue light tower is fixedly installed on the upper surface of the carrier platform, a low-temperature collector is fixedly installed on the upper surface of the carrier platform, a blue light emitting dish is fixedly installed on the upper surface of the carrier platform, a rotor is installed on the inner wall of the blue light emitting dish, the right side of the microfluidic body is fixedly connected to a discharge pipe, the outer surface of the discharge pipe is provided with an insulation sleeve, the outer surface of the insulation sleeve is fixedly installed with a temperature regulator, the right end of the discharge pipe is fixedly connected to the left side of the chip, the right side of the microfluidic body is fixedly connected to a water phase tube, the end of the water phase tube away from the microfluidic body is fixedly connected to the upper surface of the chip, the right side of the chip is fixedly installed with a circulation pipe, and the outer surface of the blue light tower is fixedly connected to a connecting pipe.

[0007] In a further embodiment, a support plate is fixedly connected to the upper surface of the supporting platform, and a PLC controller is fixedly installed on the upper surface of the support plate.

[0008] In a further embodiment, two support plates are fixedly connected to the bottom surface of the supporting platform, and support seats are fixedly installed on the bottom surfaces of the two support plates.

[0009] In a further embodiment, a stabilizing plate is fixedly mounted on the upper surface of the supporting platform, and the front side of the stabilizing plate is fixedly mounted to the back side of the low-temperature collector.

[0010] In a further embodiment, the back side of the microfluidic body is fixedly connected to a liquid inlet pipe, and the right end of the flow pipe is fixedly connected to the outer surface of the blue light tower.

[0011] In a further embodiment, the right side of the low-temperature collector is fixedly connected to a liquid outlet pipe, and the right end of the connecting pipe is fixedly connected to the left side of the low-temperature collector.

[0012] Compared with the prior art, the beneficial effects of the present invention are:

[0013] This device can perform preliminary fluid processing on liquids through the setting of the microfluidic body. By utilizing the setting of the chip, the synergistic effect of the electric field, electroosmotic flow and dielectrophoretic force generated by the bipolar electrodes can be utilized to perform high-precision manipulation of tiny particles and cells in the fluid. By configuring the insulation sleeve and the thermostat, the temperature of the fluid in transmission can be precisely controlled, so that the fluid can always be at the most suitable reaction or processing temperature, avoiding problems such as reduced sample activity and decreased reaction efficiency due to temperature fluctuations. By utilizing the setting of the blue light tower, the fluid can be specifically processed. By configuring the low-temperature collector, the activity of biological samples and the stability of chemical substances in the fluid can be effectively protected. By utilizing the setting of the blue light emitting dish and the rotor, the fluid can be processed evenly, improving the processing speed and effect. The device can then form a coherent automated processing flow, which greatly improves the accuracy and consistency of fluid processing compared to traditional distributed processing methods. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 This is a schematic diagram of the front view of the bipolar microfluidic production device.

[0015] Figure 2 This is a schematic diagram of the top view of the bipolar microfluidic production device.

[0016] Figure 3 For bipolar microfluidic production devices Figure 2 A magnified schematic diagram of the structure in the middle.

[0017] Figure 4 Schematic diagram of the rear view of the bipolar microfluidic production device.

[0018] In the figure: 1. Carrying platform; 2. Microfluidic body; 3. Chip; 4. Blue light tower; 5. Low temperature collector; 6. Discharge pipe; 7. Insulation sleeve; 8. Temperature regulator; 9. Water phase pipe; 10. Flow pipe; 11. Connecting pipe; 12. Liquid outlet pipe; 13. Support plate; 14. PLC controller; 15. Support plate; 16. Support seat; 17. Stabilizing plate; 18. Liquid inlet pipe; 19. Blue light emitting dish; 20. Rotor. DETAILED DESCRIPTION

[0019] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", etc. are only used for descriptive purposes and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, features defined as "first", "second", etc. may explicitly or implicitly include one or more of the features. In the description of the present invention, unless otherwise specified, "multiple" means two or more.

[0020] In the description of this utility model, it should be noted that, unless otherwise expressly specified or limited, the terms "installed," "connected," and "connected" should be understood in a broad sense. For example, they can refer to fixed connections, detachable connections, or integral connections; mechanical connections, electrical connections; direct connections, indirect connections through an intermediate medium, and internal communication between two components. Those skilled in the art will understand the specific meanings of the above terms in this utility model based on specific circumstances.

[0021] The following will be combined with the drawings in the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.

[0022] See also Figure 1-4, In the utility model, a bipolar microfluidic production device comprises a carrying platform 1, a microfluidic body 2 is fixedly mounted on the upper surface of the carrying platform 1, a chip 3 is fixedly mounted on the upper surface of the carrying platform 1, a blue light tower 4 is fixedly mounted on the upper surface of the carrying platform 1, a low-temperature collector 5 is fixedly mounted on the upper surface of the carrying platform 1, a blue light emitting dish 19 is fixedly mounted on the upper surface of the carrying platform 1, a rotor 20 is mounted on the inner wall of the blue light emitting dish 19, a discharge pipe 6 is fixedly connected to the right side of the microfluidic body 2, a heat preservation sleeve 7 is provided on the outer surface of the heat preservation sleeve 7, a temperature regulator 8 is fixedly mounted on the outer surface of the heat preservation sleeve 7, the right end of the discharge pipe 6 is fixedly connected to the left side of the chip 3, the right side of the microfluidic body 2 is fixedly connected to an aqueous phase pipe 9, and one end of the aqueous phase pipe 9 away from the microfluidic body 2 is fixedly connected to the upper surface of the chip 3, a flow pipe 10 is fixedly mounted on the right side of the chip 3, and a connecting pipe 11 is fixedly connected to the outer surface of the blue light tower 4. The device is configured to perform preliminary fluid processing on the liquid. By utilizing the configuration of the chip 3, the synergistic effect of the electric field, electroosmotic flow and dielectrophoretic force generated by the bipolar electrodes can be utilized to perform high-precision manipulation of tiny particles and cells in the fluid. By utilizing the configuration of the thermal insulation sleeve 7 and the thermostat 8, the temperature of the fluid in transmission can be precisely controlled, so that the fluid can always be at the most suitable reaction or processing temperature, avoiding problems such as reduced sample activity and decreased reaction efficiency due to temperature fluctuations. By utilizing the configuration of the blue light tower 4, the fluid can be specifically processed. By utilizing the configuration of the low-temperature collector 5, the activity of biological samples and the stability of chemical substances in the fluid can be effectively protected. By utilizing the configuration of the blue light emitting dish 19 and the rotor 20, the fluid can be processed evenly, and the processing speed and effect can be improved. Thus, the device can form a coherent automated processing flow, which greatly improves the accuracy and consistency of fluid processing compared to traditional distributed processing methods.

[0023] The upper surface of the supporting platform 1 is fixedly connected to a support plate 13, and a PLC controller 14 is fixedly installed on the upper surface of the support plate 13. The bottom surface of the supporting platform 1 is fixedly connected to two support plates 15, and the bottom surfaces of the two support plates 15 are fixedly installed with support seats 16. The setting of the support plate 13 can support and install the PLC controller 14. The device can be controlled by the setting of the PLC controller 14. The setting of the two support plates 15 and the two support seats 16 can support the device.

[0024] A stabilizing plate 17 is fixedly installed on the upper surface of the supporting platform 1, and the front of the stabilizing plate 17 is fixedly installed on the back of the low-temperature collector 5. The back of the microfluidic body 2 is fixedly connected with a liquid inlet pipe 18, the right end of the circulation pipe 10 is fixedly connected to the outer surface of the blue light tower 4, the right side of the low-temperature collector 5 is fixedly connected with a liquid outlet pipe 12, and the right end of the connecting pipe 11 is fixedly connected to the left side of the low-temperature collector 5. Through the setting of the stabilizing plate 17, the low-temperature collector 5 can be made more stable. By utilizing the setting of the liquid inlet pipe 18, liquid can be added into the microfluidic body 2, and through the setting of the liquid outlet pipe 12, the liquid can flow out.

[0025] The working principle of this utility model is:

[0026] First, the liquid is introduced into the microfluidic body 2 through the liquid inlet pipe 18, so that the liquid undergoes preliminary fluid treatment in the microfluidic body 2. Then the microfluidic body 2 transfers the treated fluid to the chip 3 through the discharge pipe 6, and the insulation sleeve 7 and the temperature regulator 8 outside the discharge pipe 6 accurately control the fluid temperature to ensure that the fluid enters the chip 3 at a suitable temperature. After the fluid enters the chip 3, the bipolar microfluidic technology is used to precisely control the tiny particles and cells in the fluid in the chip 3 through the synergistic effect of the electric field, electroosmosis and dielectrophoretic force generated by the bipolar electrodes. The fluid manipulated by the chip 3 enters the blue light tower 4 through the circulation pipe 10, so that the blue light tower 4 performs specific treatment on the fluid by emitting blue light. Then the treated fluid enters the low-temperature collector 5 through the connecting pipe 11, so that the low-temperature collector 5 collects the fluid at low temperature, and finally flows out through the liquid outlet pipe 12 to the blue light emitting dish 19, and the fluid is processed by the rotor 20 at the same time.

[0027] It will be apparent to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above and that the present invention can be implemented in other specific forms without departing from the spirit or essential characteristics of the present invention. Therefore, the embodiments should be considered in all respects as illustrative and non-restrictive, and the scope of the present invention is defined by the appended claims, not the foregoing description, and all variations within the meaning and range of equivalents of the claims are intended to be encompassed within the present invention. Any reference sign in a claim should not be construed as limiting the claim to which it relates.

[0028] In addition, it should be understood that although this specification is described in terms of implementation methods, not every implementation method contains only one independent technical solution. This narrative method of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment can also be appropriately combined to form other implementation methods that can be understood by those skilled in the art.

Claims

1. A bipolar microfluidic production device, characterized in that: The invention comprises a carrier platform (1), a microfluidic body (2) is fixedly mounted on the upper surface of the carrier platform (1), a chip (3) is fixedly mounted on the upper surface of the carrier platform (1), a blue light tower (4) is fixedly mounted on the upper surface of the carrier platform (1), a low-temperature collector (5) is fixedly mounted on the upper surface of the carrier platform (1), a blue light emitting dish (19) is fixedly mounted on the upper surface of the carrier platform (1), a rotor (20) is mounted on the inner wall of the blue light emitting dish (19), and a discharge pipe (6) is fixedly connected to the right side of the microfluidic body (2). The outer surface of the discharge pipe (6) is provided with a heat-insulating sleeve (7), and a temperature regulator (8) is fixedly installed on the outer surface of the heat-insulating sleeve (7). The right end of the discharge pipe (6) is fixedly connected to the left side of the chip (3), and the right side of the microfluidic body (2) is fixedly connected to a water phase tube (9). The end of the water phase tube (9) away from the microfluidic body (2) is fixedly connected to the upper surface of the chip (3), and a circulation tube (10) is fixedly installed on the right side of the chip (3). The outer surface of the blue light tower (4) is fixedly connected to a connecting tube (11).

2. A bipolar microfluidic production device according to claim 1, characterized in that: A support plate (13) is fixedly connected to the upper surface of the support platform (1), and a PLC controller (14) is fixedly installed on the upper surface of the support plate (13).

3. A bipolar microfluidic production device according to claim 1, characterized in that: Two support plates (15) are fixedly connected to the bottom surface of the support platform (1), and support seats (16) are fixedly installed on the bottom surfaces of the two support plates (15).

4. A bipolar microfluidic production device according to claim 1, characterized in that: A stabilizing plate (17) is fixedly mounted on the upper surface of the carrier platform (1), and the front surface of the stabilizing plate (17) is fixedly mounted on the back surface of the low-temperature collector (5).

5. The bipolar microfluidic production device according to claim 1, characterized in that: The back of the microfluidic main body (2) is fixedly connected to a liquid inlet pipe (18), and the right end of the circulation pipe (10) is fixedly connected to the outer surface of the blue light tower (4).

6. The bipolar microfluidic production device according to claim 1, characterized in that: The right side of the low-temperature collector (5) is fixedly connected to a liquid outlet pipe (12), and the right end of the connecting pipe (11) is fixedly connected to the left side of the low-temperature collector (5).