Incubation culture device

Abstract

The utility model relates to an incubation culture device. The incubation culture device comprises a box body, the incubator is used for accommodating samples and can be arranged in the box body; the heating mechanism is arranged in the box body, and the heating mechanism can heat a sample in the incubator. The incubation culture device provided by the utility model is high in detection flux, good in temperature uniformity in the incubator, high in temperature rise speed and high in detection efficiency.

Description

Technical Field

[0001] The utility model relates to the technical field of in vitro diagnosis, in particular to an incubation and culture device. Background Art

[0002] Before or during testing, the sample to be tested often requires a suitable external temperature environment to promote its growth. Therefore, a heating device is often required to control the temperature of the environment space. However, existing incubation and culture devices have the following shortcomings:

[0003] In the prior art, the incubator includes a heater and an air supply duct. One end of the air supply duct is connected to the heater, and the other end is connected to the interior of the incubator, so that the air heated by the heater is sent into the incubator through the air supply duct. However, the space inside the incubator is large, resulting in poor temperature uniformity inside the incubator, causing deviations in the test results. In addition, the large space inside the incubator will also cause the temperature inside the incubator to rise slowly, resulting in low detection efficiency. Utility Model Content

[0004] The purpose of the present invention is to provide an incubation and cultivation device to at least solve one of the above technical problems.

[0005] To achieve the above objectives, the present invention provides an incubation and cultivation device, comprising:

[0006] Box;

[0007] an incubator, for accommodating samples and capable of being disposed within the chamber;

[0008] A heating mechanism is provided in the box body, and the heating mechanism can heat the sample in the incubator.

[0009] Optionally, the box body includes a guide structure, which allows air to circulate between the heating mechanism and the incubator.

[0010] Optionally, the air guide structure includes an air supply duct and a return air duct, and the heating mechanism, the air supply duct, the incubator and the return air duct are connected in sequence to form a loop.

[0011] Optionally, the air supply outlet end of the air supply duct is connected to the first side of the incubator, and the return air inlet end of the return air duct is connected to the second side of the incubator, and the first side and the second side are arranged opposite to each other.

[0012] Optionally, the box body further includes a first box wall and a second box wall, the supply air duct is arranged in the first box wall, and the return air duct is arranged in the second box wall.

[0013] Optionally, the first box wall and the second box wall are arranged opposite to each other; and / or

[0014] The incubator is arranged between the first box wall and the second box wall, and the first box wall is arranged opposite to the first side of the incubator, and the second side of the incubator is arranged opposite to the second box wall.

[0015] Optionally, the air supply outlet end includes a plurality of air inlet holes arranged at intervals; and / or the return air inlet end includes a plurality of air outlet holes arranged at intervals.

[0016] Optionally, the air guide structure further includes an air supply buffer portion for buffering hot air and / or distributing hot air evenly, and the air supply duct and the air supply outlet end are connected through the air supply buffer portion; and / or

[0017] The air guide structure further includes a return air buffer portion for buffering air, and the return air duct and the return air inlet end are communicated with each other through the return air buffer portion.

[0018] Optionally, the air supply buffer is arranged in the air supply duct; and / or

[0019] The air supply buffer portion is arranged adjacent to the air supply outlet end; and / or

[0020] The return air buffer is arranged in the return air duct; and / or

[0021] The return air buffer portion is arranged adjacent to the return air inlet end.

[0022] Optionally, the air supply buffer portion includes a first buffer frame, the first buffer frame is provided with a first opening and an air supply outlet, the first opening is arranged opposite to the air supply outlet end, the air supply outlet is connected to the air supply duct, and the cross-sectional area of ​​the first opening is larger than the cross-sectional area of ​​the air supply outlet; and / or

[0023] The return air buffer portion includes a second buffer frame, the second buffer frame is provided with a second opening and a return air outlet, the second opening is arranged opposite to the return air inlet end, the return air outlet is connected to the return air duct, and the cross-sectional area of ​​the second opening is larger than the cross-sectional area of ​​the return air outlet.

[0024] Optionally, the first buffer frame encloses a first buffer space, and the first opening and the air supply port are both in communication with the first buffer space;

[0025] The second buffer frame encloses a second buffer space, and the second opening and the return air outlet are both in communication with the second buffer space.

[0026] Optionally, the air supply buffer portion further includes a first partition portion, the first partition portion is provided with a plurality of first vent holes, and the first partition portion divides the first buffer space into two connected spaces; and / or

[0027] The return air buffer portion further includes a second partition portion, on which a plurality of second vent holes are formed. The second partition portion divides the second buffer space into two communicating spaces.

[0028] Optionally, the first box wall includes a first inner plate and a first outer plate that are spaced apart, and the air supply duct is formed between the first inner plate and the first outer plate; and / or,

[0029] The second box wall includes a second inner plate and a second outer plate that are spaced apart to form the return air duct between the second inner plate and the second outer plate.

[0030] Optionally, there are one or more incubators.

[0031] Optionally, each of the incubators is provided with at least one corresponding air supply outlet; and / or

[0032] Each incubator is provided with at least one corresponding return air inlet.

[0033] Optionally, the box body further includes a partition, which is used to separate two adjacent incubators, and / or the partition is used to separate the incubator and the heating mechanism.

[0034] Optionally, the heating mechanism includes an air driving member, which is used to drive air to flow between the heating mechanism and the incubator.

[0035] Optionally, a receiving space is formed between the partition and the bottom of the box body, the heating mechanism is arranged in the receiving space, and the receiving space is communicated with the guide structure.

[0036] Optionally, the incubator includes a first shell, the first shell includes a first side wall and a second side wall that are oppositely arranged, and the flow guide structure is connected to the incubator through the first side wall and the second side wall.

[0037] Optionally, the first shell further includes a bottom wall, the bottom wall is provided with a plurality of first air holes; and / or

[0038] The first side wall and the second side wall are both provided with second air holes, and the flow guide structure is connected with the incubator through the second air holes.

[0039] Optionally, the incubator further includes a first heating unit, and the first heating unit is used to heat the sample in the incubator.

[0040] Optionally, the incubation and cultivation device further includes a control module, which is electrically connected to the heating mechanism and the first heating unit.

[0041] Optionally, the incubation and cultivation device further comprises a fresh air mechanism connected to the box body, wherein the fresh air mechanism is used to filter air, and external air enters the box body and / or the heating mechanism through the fresh air mechanism.

[0042] Optionally, the heating mechanism includes a second shell and a second heating unit, and the second heating unit is arranged in the second shell.

[0043] Optionally, the heating mechanism further includes a first temperature detection unit and / or a temperature protection unit disposed in the second shell.

[0044] Optionally, the incubator further includes a second temperature detection unit, which is used to detect the temperature inside the incubator.

[0045] Optionally, the incubation and cultivation device further includes a heat dissipation mechanism, which is used to dissipate heat for the heating mechanism.

[0046] As can be seen from the above, the incubation and culture device provided by the present invention includes a housing, an incubator, and a heating mechanism. The incubator is used to accommodate samples and can be disposed within the housing. The heating mechanism is disposed within the housing and is capable of heating the samples within the incubator. Since both the heating mechanism and the incubator are disposed within the housing, rapid heating of the samples can be achieved.

[0047] The guide structure can guide the air inside the box so that the air circulates along a preset path, so that the temperature in the incubator can reach the target temperature as soon as possible, and each position point in the incubator can reach the set target temperature ±1.5°C, ensuring the temperature uniformity in the incubator. The first heating unit can independently adjust the temperature in the incubator corresponding to it, so that the temperature in the incubator can be accurately compensated. In the initial rising stage, heating is performed by the heating mechanism and the first heating unit. When the temperature in a single incubator is lower than the target temperature, the sample in the incubator can be heated by individually controlling the corresponding first heating unit, thereby further increasing the heating speed and improving the detection efficiency.

[0048] The incubation and cultivation device can accurately control the temperature inside a large-capacity chamber and ensure its temperature accuracy and uniformity. At the same time, it is convenient to embed a fluorescence detection device for synchronous detection to improve detection efficiency.

[0049] The incubation and culture device has a high detection throughput. Each layer of incubator can incubate 400 samples. Setting up three incubators can meet the needs of incubating 1,200 samples at the same time. BRIEF DESCRIPTION OF THE DRAWINGS

[0050] Figure 1 It is a structural schematic diagram of the incubation and cultivation device provided by an embodiment of the present utility model;

[0051] Figure 2a This is a schematic diagram of the structure of the incubation and cultivation device provided by the embodiment of the utility model. Figure 1 ;

[0052] Figure 2b yes Figure 2a A partial enlarged view of point E in the middle;

[0053] Figure 2c yes Figure 2a A partial enlarged view of point F in the middle;

[0054] Figure 3 This is a second schematic diagram of the structure of the incubation and cultivation device provided in an embodiment of the present utility model;

[0055] Figure 4a This is a partial structural diagram of the incubation and cultivation device provided by an embodiment of the present utility model;

[0056] Figure 4b yes Figure 4a Cross-sectional view at the middle BB;

[0057] Figure 4c The invention provides an incubation and cultivation device with an explosion-proof structure. Figure 1 ;

[0058] Figure 4d This is a structural schematic diagram of the incubation and cultivation device provided by an embodiment of the utility model from another perspective;

[0059] Figure 4e yes Figure 4d Cross-sectional view at CC;

[0060] Figure 4f yes Figure 4e A partial enlarged view of the M in the middle;

[0061] Figure 5a This is the second exploded view of the incubation and culture device provided by an embodiment of the present utility model;

[0062] Figure 5b yes Figure 5a A partial enlarged view of point G in the middle;

[0063] Figure 5c yes Figure 5a A partial enlarged view of the H in the middle;

[0064] Figure 5d yes Figure 5a A local enlarged view of the K point in the middle;

[0065] Figure 6 yes Figure 3 A partial enlarged view of point A in the middle;

[0066] Figure 7 This is a schematic diagram of the structure of the incubation and cultivation device provided by the embodiment of the utility model. Figure 3 ;

[0067] Figure 8 yes Figure 7 A partial enlarged view of point B in the middle;

[0068] Figure 9 This is a structural diagram of the return air buffer portion provided by an embodiment of the present utility model;

[0069] Figure 10 This is a structural diagram of the air supply buffer portion provided by an embodiment of the present utility model;

[0070] Figure 11 This is a schematic structural diagram of an incubator provided by an embodiment of the present utility model;

[0071] Figure 12 This is a schematic structural diagram of the incubator provided by an embodiment of the utility model from another perspective;

[0072] Figure 13 This is a partial structural diagram of an incubator provided by an embodiment of the utility model;

[0073] Figure 14 yes Figure 13 A partial enlarged view of point C in the middle;

[0074] Figure 15 This is an exploded view of an incubator provided by an embodiment of the present utility model;

[0075] Figure 16 It is a partial structural schematic diagram of the incubator provided in an embodiment of the utility model.

[0076] In the picture:

[0077] 1. Incubator; 15. First shell; 151. First side wall; 152. Second side wall; 1521. Second air hole; 153. Bottom wall; 1531. First air hole; 154. Top wall; 1541. Hole position; 1542. Upper top plate; 1543. Lower top plate; 16. First heating unit; 17. First side; 18. Second side; 19. Positioning plate; 191. Positioning hole;

[0078] 2. Box body;

[0079] 21. Air guide structure; 211. Air supply duct; 212. Air supply outlet; 2121. Air inlet; 213. Return air duct; 214. Return air outlet; 215. Return air inlet; 2151. Air outlet; 216. Air supply inlet;

[0080] 22. Box bottom; 23. Accommodation space; 24. First box wall; 241. First inner panel; 242. First outer panel; 25. Second box wall; 251. Second inner panel; 252. Second outer panel;

[0081] 26. Air supply buffer; 261. First buffer frame; 262. First buffer space; 263. First partition; 264. Air supply port; 265. First opening; 266. First vent; 267. Air supply pipe;

[0082] 27. Return air buffer; 271. Second buffer frame; 272. Second buffer space; 273. Second partition; 274. Return air outlet; 275. Second opening; 276. Second vent hole; 277. Return air duct;

[0083] 28. Partition;

[0084] 29, rear box wall; 291, third outer panel; 2911, heat dissipation holes; 292, middle panel; 293, third inner panel;

[0085] 3. Heating mechanism; 31. Air driving member; 311. Exhaust fan; 312. Blower; 32. Second housing;

[0086] 4. Fresh air mechanism; 5. Heat dissipation mechanism; 7. Heating power supply;

[0087] 10. Fluorescence detection device;

[0088] 100. Culture tube. DETAILED DESCRIPTION

[0089] The technical solution of the present invention will be further described below with reference to the accompanying drawings and through specific embodiments. It should be understood that the specific embodiments described herein are merely for the purpose of explaining the present invention, and are not intended to limit the present invention. It should also be noted that, for ease of description, the accompanying drawings only illustrate portions relevant to the present invention, not all of it.

[0090] Some directional words are defined in the present invention. Unless otherwise stated, the directional words used, such as "up", "down", "left", "right", "inside" and "outside", are used for ease of understanding and therefore do not constitute a limitation on the scope of protection of the present invention.

[0091] In the present invention, unless otherwise expressly specified or limited, a first feature being "above" or "below" a second feature may include the first and second features being in direct contact, or may include the first and second features being in contact not directly but through another feature between them. Moreover, a first feature being "above," "above," and "above" a second feature may include the first feature being directly above or obliquely above the second feature, or may simply mean that the first feature is higher in level than the second feature. A first feature being "below," "below," and "below" a second feature may include the first feature being directly below or obliquely below the second feature, or may simply mean that the first feature is lower in level than the second feature.

[0092] In the description of this utility model, unless otherwise specified or limited, the terms "connected," "connect," and "fixed" should be understood in a broad sense. For example, they can refer to fixed connection, detachable connection, or integration; mechanical connection or electrical connection; direct connection or indirect connection through an intermediate medium; internal communication between two components or interaction between two components. Those skilled in the art will understand the specific meanings of the above terms in this utility model based on the specific circumstances.

[0093] This embodiment provides an incubation and culture device for incubating samples, but is not limited thereto, to improve temperature uniformity and heating speed.

[0094] like Figure 1 As shown, the incubation and culture device provided in this embodiment includes a housing 2, an incubator 1, and a heating mechanism 3. The incubator 1 is used to accommodate samples and can be arranged in the housing 2. The heating mechanism 3 is arranged in the housing 2 and can heat the samples in the incubator 1. The heating mechanism 3 and the incubator 1 are both arranged in the housing 2. The heating mechanism 3 can heat all samples, which can achieve rapid temperature increase of the samples.

[0095] like Figure 1 and Figure 2a As shown, the incubator 1 can be optionally pulled into the housing 2. After the incubator 1 is pulled out of the housing 2, a sample can be placed into the incubator 1 or taken out of the incubator 1. When the incubator 1 is pushed into the housing 2, the sample can be placed in the housing 2 and heated by the heating mechanism 3.

[0096] In this embodiment, the housing 2 can be provided with three incubators 1, which can be arranged in sequence in a vertical direction, thereby increasing the detection throughput. Of course, in other optional embodiments, the number of incubators 1 is not limited to this, and can be more than three or less than three, such as one, two, four, or five incubators 1. When there are multiple incubators 1, the multiple incubators 1 can also be placed in sequence in a horizontal direction. In this embodiment, the heating mechanism 3 can heat all incubators 1, quickly raising the temperature of each incubator 1 and improving detection efficiency.

[0097] The box body 2 can be roughly a rectangular parallelepiped, such as Figure 2a As shown, the box body 2 may include a first box wall 24 and a second box wall 25 , and the first box wall 24 and the second box wall 25 may be arranged opposite to each other.

[0098] The box body 2 may further include a box bottom 22 , which is connected to the lower ends of the first box wall 24 and the second box wall 25 .

[0099] like Figure 3 As shown, the box body 2 may further include a rear box wall 29, which is connected to the rear ends of the first box wall 24 and the second box wall 25. The front end of the box body 2 is open for the incubator 1 to be inserted into the box body 2. When the incubator 1 is inserted into the box body 2, the incubator 1 is located between the first box wall 24 and the second box wall 25.

[0100] like Figure 4c As shown, the incubation and cultivation device may further include a fresh air mechanism 4 connected to the housing 2, the fresh air mechanism 4 being used to filter air, and external air enters the housing 2 and / or the heating mechanism 3 through the fresh air mechanism 4, thereby ensuring clean air in the housing 2. Optionally, the fresh air mechanism 4 is disposed at the lower end of the housing 2, i.e., external air enters the housing 2 from the lower end.

[0101] The heating mechanism 3 can be arranged horizontally to one side of the fresh air mechanism 4. After passing through the fresh air mechanism 4, the outside air can directly enter the heating mechanism 3, and then the air can flow smoothly into the incubator 1. Because low-temperature air tends to sink, the outside low-temperature air enters the box body 2 and the heating mechanism 3 from the bottom, thereby preventing the outside low-temperature air from entering the incubator 1 without passing through the heating mechanism 2.

[0102] like Figure 2a and Figure 3 As shown, the heating mechanism 3 may optionally include a second housing 32 and a second heating unit (not shown in the figure), and the second heating unit is disposed in the second housing 32. Optionally, the second housing 32 has a hole on one side facing the fresh air mechanism 4, so that air passing through the fresh air mechanism 4 enters the second housing 32 through the hole. Optionally, the second heating unit may be a PTC heater or a resistance wire.

[0103] In order to increase the flow rate of air in the box body 2, the heating mechanism 3 may optionally include an air drive 31, which is used to drive the air to flow between the heating mechanism 3 and the incubator 1, so that the air drive 31 can quickly deliver the heated air to the incubator 1, thereby increasing the heating rate in the incubator 1 and increasing the temperature adjustment speed in the incubator 1.

[0104] like Figure 2a 、 Figure 2b and Figure 2c As shown, the air drive member 31 may include a fan. Specifically, a blower 312 is provided on one side of the second shell 32, and an exhaust fan 311 is provided on the other side. The blower 312 and the exhaust fan 311 are arranged opposite to each other. The exhaust fan 311 can draw the air in the incubator 1 back to the heating mechanism 3, and the blower 312 can blow the air heated by the heating mechanism 3 into the incubator 1, thereby further increasing the flow speed of the airflow and increasing the temperature rise rate in the incubator 1.

[0105] To facilitate control of the power of the second heating unit, the heating mechanism 3 may further include a first temperature detection unit and / or a temperature protection unit disposed within the second housing 32. The first temperature detection unit is configured to detect the air temperature within the second housing 32. When the air within the second housing 32 is below a preset temperature, the power of the second heating unit may be increased. When the temperature within the second housing 32 is above a preset temperature, the power of the second heating unit may be reduced. When the temperature within the second housing 32 is too high, the temperature protection unit activates, causing the second heating unit to stop operating and simultaneously activating the fresh air mechanism 4. Optionally, the temperature protection unit may be a temperature protector as known in the art, which may automatically deactivate the second heating unit when the temperature is too high.

[0106] like Figure 5a and Figure 5b As shown, the box body 2 may further include a heat dissipation mechanism 5, which is used to dissipate heat for the heating mechanism 3, thereby preventing the heating mechanism 3 from overheating. The heat dissipation mechanism 5 may be a fan.

[0107] like Figure 4d-Figure 5a As shown, specifically, the heat dissipation mechanism 5 is connected to the rear box wall 29. Optionally, the rear box wall 29 may include a third outer plate 291 and a third inner plate 293. The third outer plate 291 is located on the outside of the third inner plate 293. The heat dissipation mechanism 5 may be connected to the third outer plate 291 and located on the inside of the third outer plate 291. The third outer plate 291 may have heat dissipation holes 2911 (such as Figure 5c ), the heat dissipation mechanism 5 is directly opposite to the heat dissipation hole 2911 to dissipate the hot air.

[0108] The rear box wall 29 may further include an intermediate plate 292, which is located between the third outer plate 291 and the third inner plate 293. The intermediate plate 292 may be connected to a heating power source 7 (eg, Figure 5d ), multiple heating power supplies 7 can be provided to respectively power the heating mechanism 3 and multiple first heating units 16 (described in detail later). The intermediate plate 292 can reduce or eliminate the impact of the heating power supply 7 on the incubator 1.

[0109] like Figure 2a-Figure 8 As shown, the housing 2 may optionally include a guide structure 21 that circulates air between the heating mechanism 3 and the incubator 1. The guide structure 21 guides the air within the housing 2, increasing the air flow rate and allowing the air to circulate along a predetermined path, thereby ensuring that each point within the incubator 1 reaches the set target temperature within ±1.5°C, thereby ensuring temperature uniformity within the incubator 1.

[0110] like Figure 3 As shown, the box body 2 may further include a partition 28 , which may be used to separate the incubator 1 and the heating mechanism 3 , thereby preventing unheated air from directly entering the incubator 1 and ensuring temperature accuracy and temperature uniformity within the incubator 1 .

[0111] Illustratively, a receiving space 23 is formed between the partition 28 and the bottom 22 of the box body 2, the heating mechanism 3 is arranged in the receiving space 23, and the receiving space 23 is connected to the guide structure 21, so that the heated air in the receiving space 23 enters the incubator 1 through the guide structure 21, and the air in the incubator 1 flows back into the receiving space 23.

[0112] There can be multiple partitions 28, and the partitions 28 can also be used to separate two adjacent incubators 1 to reduce or avoid the exchange of airflow between the incubators 1, while ensuring that the airflow flows in a preset direction, that is, the airflow flows from the heating mechanism 3 into the guide structure 21, and then flows into the incubators 1 respectively, and finally flows back to the heating mechanism 3 through the air circulation mechanism. This can ensure the temperature uniformity in each incubator 1 and improve the success rate of sample incubation.

[0113] like Figure 4a-4c As shown, the air guide structure 21 may optionally include an air supply duct 211 and an air return duct 213. The heating mechanism 3, the air supply duct 211, the incubator 1, and the air return duct 213 are sequentially connected to form a loop. The air supply duct 211 and the air return duct 213 may define the air flow path, thereby guiding the airflow.

[0114] Optionally, the supply air duct 211 is arranged in the first box wall 24, and the return air duct 213 is arranged in the second box wall 25. In this embodiment, the first box wall 24 and the second box wall 25 are arranged relative to each other, so that the supply air duct 211 and the return air duct 213 are also arranged relative to each other. The supply air duct 211 and the return air duct 213 are independently arranged, separated from each other, and do not interfere with each other.

[0115] The incubator 1 has a first side 17 and a second side 18. The first side 17 and the second side 18 are disposed opposite each other. The first side 17 is disposed opposite a first wall 24, and the second side 18 is disposed opposite a second wall 25. An air supply duct 211 is disposed within the first wall 24, and an air return duct 213 is disposed within the second wall 25. This allows hot air to enter the incubator 1 through the first side 17 and exit through the second side 18. The hot air can pass through the incubator 1, improving temperature uniformity within the incubator 1.

[0116] To facilitate the formation of the return air duct 213, the second box wall 25 may optionally include a second inner plate 251 and a second outer plate 252 spaced apart from each other, with the return air duct 213 formed between the second inner plate 251 and the second outer plate 252. The structure of the second box wall 25 can form the return air duct 213 and also form the box wall of the box body 2.

[0117] like Figure 4c As shown, the return air duct 213 has a return air inlet 215 and a return air outlet 214. The return air inlet 215 is connected to the second side 18 of the incubator 1. Air flowing out of the incubator 1 flows out of the second side 18, then enters the return air duct 213 through the return air inlet 215, and finally enters the heating mechanism 3 again through the return air outlet 214. Preferably, the return air inlet 215 is located on the inner side of the second chamber wall 25. More specifically, the return air outlet 214 is located on the second inner panel 251.

[0118] like Figure 5a As shown, to facilitate the formation of the air supply duct 211, the first box wall 24 may optionally include a first inner plate 241 and a first outer plate 242 spaced apart from each other, with the air supply duct 211 formed between the first inner plate 241 and the first outer plate 242. The structure of the first box wall 24 can form both the air supply duct 211 and the box wall of the box body 2.

[0119] The air duct 211 has an air outlet 212 and an air inlet 216. Hot air from the heating mechanism 3 flows into the air duct 211 through the air inlet 216 and out through the air outlet 212. The air outlet 212 communicates with the first side 17 of the incubator 1, allowing hot air to enter the incubator 1 from the first side 17. Preferably, the air outlet 212 is located on the inner side of the first chamber wall 24, more specifically, on the first inner panel 241. The air inlet 216 is located on the inner side of the first chamber wall 24, more specifically, on the first inner panel 241.

[0120] It can be understood that the air supply duct 211 is connected to the heating mechanism 3 through the air supply inlet end 216 , and the return air duct 213 is connected to the heating mechanism 3 through the return air outlet end 214 .

[0121] like Figure 3 and Figure 6 As shown, the return air inlet end 215 may include a plurality of air outlet holes 2151 spaced apart from each other. The air outlet holes 2151 may make the air entering the incubator 1 more evenly distributed, thereby improving the temperature uniformity in the incubator 1.

[0122] like Figure 7 and Figure 8 As shown, the air outlet end 212 may include a plurality of air inlet holes 2121 arranged at intervals. The air inlet holes 2121 can allow the air in the incubator 1 to flow out of the incubator 1 evenly, thereby improving the temperature uniformity in the incubator 1.

[0123] like Figure 3 and Figure 7 As shown, for example, when multiple incubators 1 are installed in the housing 2, the number of return air inlet ports 215 is the same as the number of incubators 1, and the number of supply air outlet ports 212 is the same as the number of incubators 1. The return air inlet ports 215 are arranged in a one-to-one correspondence with the incubators 1, and the supply air outlet ports 212 are arranged in a one-to-one correspondence with the incubators 1. Of course, one incubator 1 may also be provided with multiple return air inlet ports 215 and multiple supply air outlet ports 212.

[0124] like Figure 5a As shown, the air guide structure 21 may further include an air supply buffer portion 26 for buffering and / or evenly distributing the hot air. The air supply duct 211 and the air supply outlet end 212 are connected via the air supply buffer portion 26. That is, the air in the air supply duct 211 passes through the air supply buffer portion 26 before entering the air supply outlet end 212. The air supply buffer portion 26 slows down the air velocity entering the incubator 1 and guides the hot air for a more even distribution, thereby ensuring an even distribution of the hot air entering the incubator 1.

[0125] Specifically, the air supply buffer 26 is disposed within the air supply duct 211. In this embodiment, the air supply buffer 26 is disposed between the first inner panel 241 and the first outer panel 242, so that hot air within the air supply duct 211 can enter the air supply buffer 26 and the hot air in the air supply buffer 26 can enter the incubator 1. The air supply buffer 26 is disposed adjacent to the air supply outlet 212, so that all hot air in the air supply buffer 26 can enter the incubator 1.

[0126] like Figure 4c and Figure 7 As shown, the air guide structure 21 may further include a return air buffer 27 for buffering air. The return air duct 213 and the return air inlet 215 are connected via the return air buffer 27. That is, the air in the return air duct 213 passes through the return air buffer 27 before entering the return air inlet 215. The return air buffer 27 can slow down the flow of hot air out of the incubator 1, allowing for sufficient heat exchange between the hot air and the samples. At the same time, it can also ensure that air in all parts of the incubator 1 flows out of the incubator 1 evenly.

[0127] Specifically, the return air buffer 27 is disposed within the return air duct 213. In this embodiment, the return air buffer 27 is disposed between the second inner panel 251 and the second outer panel 252. This allows air from the incubator 1 to enter the supply air buffer 26, and facilitates air from the supply air buffer 26 to enter the return air duct. The return air buffer 27 is disposed adjacent to the return air inlet 215, allowing air from the incubator 1 to enter the return air buffer 27.

[0128] like Figure 9 As shown, the air supply buffer portion 26 may include a first buffer frame 261, which can circulate hot air. The first buffer frame 261 is provided with a first opening 265 and an air supply port 264. The air supply port 264 is connected to the air supply duct 211, so that hot air in the air supply duct 211 enters the air supply buffer portion 26 through the air supply port 264. The first opening 265 is arranged opposite the air supply outlet end 212, so that hot air enters the air supply outlet end 212 through the first opening 265. The cross-sectional area of ​​the first opening 265 is larger than the cross-sectional area of ​​the air supply port 264, which can slow down the speed of hot air entering the incubator 1.

[0129] The air supply buffer portion 26 may further include an air supply pipe 267 . The air supply pipe 267 is connected to the air supply port 264 . The air supply pipe 267 may guide air into the first buffer frame 261 .

[0130] The first buffer frame 261 forms a first buffer space 262 . The first opening 265 and the air outlet 264 are both connected to the first buffer space 262 . The first buffer space 262 can make the air more evenly distributed in the first buffer frame 261 .

[0131] The air supply buffer portion 26 may further include a first partition 263 having a plurality of first vent holes 266 formed therein. The first partition 263 divides the first buffer space 262 into two interconnected spaces. The first partition 263 further slows the flow of air within the first buffer space 262, further evenly distributing the heated air. It will be appreciated that the first opening 265 communicates with one of the spaces, while the air supply port 264 communicates with the other space, allowing heated air to pass through the first partition 263.

[0132] like Figure 10 As shown, the return air buffer portion 27 may include a second buffer frame 271 having a second opening 275 and a return air port 274. The second opening 275 is disposed opposite the return air inlet end 215, allowing air within the incubator 1 to enter the second buffer frame 271 through the return air inlet end 215 and the second opening 275. The return air port 274 is connected to the return air duct 213, allowing air within the second buffer frame 271 to enter the return air duct 213 through the return air port 274. The cross-sectional area of ​​the second opening 275 is larger than the cross-sectional area of ​​the return air port 274, thereby slowing down the speed at which air within the incubator 1 enters the second buffer frame 271 and allowing air within the second buffer frame 271 to flow quickly into the return air duct 213.

[0133] The return air buffer portion 27 may further include a return air pipe 277 . The return air pipe 277 is connected to the return air port 274 . The return air pipe 277 may guide air into the return air duct 213 .

[0134] The second buffer frame 271 forms a second buffer space 272 . The second opening 275 and the return air port 274 are both connected to the second buffer space 272 . The second buffer space 272 can slow down the speed at which the air in the incubator 1 enters the return air duct 213 .

[0135] The return air buffer 27 may also include a second partition 273, which is provided with a plurality of second vents 276. The second partition 273 divides the second buffer space 272 into two connected spaces. The second partition 273 further slows the flow of air into the second buffer space 272. It will be appreciated that the second opening 275 communicates with one of the spaces, while the return air outlet 274 communicates with the other space, allowing hot air to pass through the second partition 273.

[0136] like Figure 11As shown, the incubator 1 may include a first housing 15, which may include a first side wall 151 and a second side wall 152 disposed opposite each other. The flow guide structure 21 is connected to the incubator 1 through the first side wall 151 and the second side wall 152. Specifically, the first side wall 151 is located on the first side 17 of the incubator 1, and the second side wall 152 is located on the second side 18 of the incubator 1.

[0137] Second air holes 1521 are formed on both the first side wall 151 and the second side wall 152 , and the flow guiding structure 21 is connected to the incubator 1 through the second air holes 1521 .

[0138] like Figure 12 As shown, the first housing 15 may further include a bottom wall 153, which may be connected to the lower ends of the first side wall 151 and the second side wall 152. The bottom wall 153 is provided with a plurality of first air holes 1531. For example, a gap is formed between the bottom wall 153 and the partition 28 located below it. The first air holes 1531 allow air inside the incubator 1 to circulate with air outside the incubator 1 (which is also located inside the housing 2), thereby making the temperature inside the entire housing 2 uniform, thereby facilitating the maintenance of a uniform temperature inside the incubator 1.

[0139] like Figure 13-15 As shown, the first housing 15 may further include a top wall 154, which may be connected to the upper ends of the first side wall 151 and the second side wall 152. The top wall 154 is provided with a plurality of holes 1541. Exemplarily, the holes 1541 are arranged in an array. The culture tubes 100 for holding samples may be inserted into the holes 1541, thereby allowing the samples in the culture tubes 100 to be placed in the incubator 1.

[0140] Optionally, the incubator 1 may further include a positioning plate 19 disposed on the lower side of the top wall 154. The positioning plate 19 has a positioning hole 191, into which the culture tube 100 can be inserted. Furthermore, the position near the lower end of the culture tube 100 can be inserted into the positioning hole 191, and the lower end of the culture tube 100 passes through the positioning hole 191 and is located on the lower side of the positioning plate 19. The positioning plate 19 can improve the stability of the placement of the culture tube 100.

[0141] like Figure 15 and Figure 16 As shown, the incubation and culture device can also include a fluorescence detection device 10, which detects the sample through the bottom of the culture tube 100. In this way, the opening of the culture tube 100 can be covered with a cover body, so that the air does not directly contact the sample, preventing the sample from being contaminated.

[0142] The fluorescence detection device 10 is disposed in the incubator 1 and is located at the lower side of the positioning plate 19 . The fluorescence detection device 10 performs fluorescence detection on the sample through the bottom of the culture tube 100 .

[0143] The fluorescence detection device 10 can be a fluorescence detection structure in the prior art. Its specific principles and structure are not described in detail, as long as it can perform fluorescence detection on the sample. In this embodiment, the fluorescence detection device 10 can include multiple fluorescence detection units, with one fluorescence detection unit corresponding to each culture tube 100, so as to detect the sample separately.

[0144] Optionally, the top wall 154 may include an upper top plate 1542 and a lower top plate 1543, with the upper top plate 1542 being located outside the lower top plate 1543. The incubator 1 may further include a first heating unit 16, which is used to heat the sample within the incubator 1. Exemplarily, the first heating unit 16 is sandwiched between the lower top plate 1543 and the upper top plate 1542, thereby facilitating the fixation of the first heating unit 16. Holes may be provided on the first heating unit 16, the upper top plate 1542, and the lower top plate 1543, with the holes on the first heating unit 16, the upper top plate 1542, and the lower top plate 1543 being arranged opposite each other to form hole positions 1541.

[0145] The first heating unit 16 can independently adjust the temperature within its corresponding incubator 1, thereby accurately compensating for the temperature within the incubator 1. Optionally, the first heating unit 16 can be in the form of a sheet. For example, during the initial ramp-up phase, heating is performed via the heating mechanism 3 and the first heating unit 16. When the temperature within a single incubator 1 falls below the target temperature, the corresponding first heating unit 16 can be individually controlled to heat the sample within the incubator 1, further accelerating the ramp-up rate and improving detection efficiency.

[0146] Optionally, the incubator 1 may further include a second temperature detection unit (not shown in the figure), which is used to detect the temperature inside the incubator 1. The second temperature detection unit may be a temperature sensor, etc., and the first heating unit 16 may adjust the temperature inside the incubator 1 according to the temperature detected by the second temperature detection unit.

[0147] Optionally, the incubation and cultivation device may further include a control module, which is electrically connected to the heating mechanism 3 and the first heating unit 16, and the first temperature detection unit and the second temperature detection unit may also be connected to the control module. The first temperature detection unit and the second temperature detection unit transmit the detected temperature values ​​to the control module, and the control module controls the first heating unit 16 and the heating mechanism 3 according to the received temperature values. The control module may be a centralized or distributed controller. For example, the controller may be a single single-chip microcomputer or a distributed multi-chip microcomputer. The single-chip microcomputer may run a control program to control the above-mentioned components to realize their functions.

[0148] Exemplarily, the control module may also be electrically connected to the fresh air mechanism 4 to control the start and stop of the fresh air mechanism 4 .

[0149] When the temperature inside the incubator 1 is low, the control module can control the fresh air mechanism 4 to close, and the outside air cannot enter the box body 2. The control module controls the first heating unit 16 and the heating mechanism 3 to heat the hot air inside the incubator 1, and the guide structure 21 transports the air heated by the heating mechanism 3 into the incubator 1, so that the temperature inside the incubator 1 can reach the target temperature as soon as possible; when the incubator 1 needs to be cooled, the control module can control the fresh air mechanism 4 to open, and the control module controls the first heating unit 16 and the heating mechanism 3 to stop working or reduce the power to lower the temperature inside the incubator 1.

[0150] Each layer of incubator 1 in the incubation and cultivation device provided in this embodiment can incubate 400 samples, and setting up three incubators 1 can meet the needs of incubating 1,200 samples at the same time. The incubation and cultivation device can accurately control the temperature inside the large-capacity box 2, and ensure its temperature accuracy and uniformity. At the same time, it is convenient to embed the fluorescence detection device 10 for synchronous detection to improve the detection efficiency. The incubation and cultivation device provided in this embodiment can accurately control the compensation temperature of the first heating unit 16, and at the same time cooperate with the guide structure 21 to achieve a dynamic balance of the temperature in the box 2, so that the temperature in the incubator 1 reaches the target temperature of ±1.5°C. In this embodiment, the fresh air mechanism 4 and the guide structure 21 perform rapid temperature control, so that the temperature of each hole 1541 in the incubator 1 reaches the incubation temperature condition, meeting the needs of rapid incubation and cultivation.

[0151] This embodiment also provides a temperature control method, and the incubation and cultivation device can perform the temperature control method. The temperature control method may include:

[0152] The environment inside the box 2 is heated by the heating mechanism 3 .

[0153] The heating mechanism 3 can heat the entire box 2 , thereby quickly heating all samples in the box 2 .

[0154] When multiple incubators 1 are used, the first heating unit 16 heats and / or compensates the temperature within each incubator 1 to reach the target temperature. If the temperature within a particular incubator 1 falls below the target, the first heating unit 16 can be precisely controlled to compensate, maintaining the temperature within the entire chamber 2 within ±1.5°C of the target temperature. During the initial ramp-up phase, the heating mechanism 3 and the first heating unit 16 work together to achieve rapid temperature increase.

[0155] When the temperature inside the incubator 1 is higher than the target temperature, the fresh air mechanism 4 introduces outside air into the incubator 2 and / or the heating mechanism 3. The outside air temperature is lower than the air temperature inside the incubator 2. Therefore, introducing outside air into the incubator 2 can quickly lower the temperature inside the incubator 1, achieving rapid temperature control.

[0156] Optionally, when the temperature inside the incubator 1 is lower than the target temperature, the heating mechanism 3 operates at full load, exemplarily, the second heating unit and the air drive 31 both operate at full load; when the temperature inside the incubator 1 is higher than the target temperature, the heating mechanism 3 operates at light load, exemplarily, the second heating unit and the air drive 31 both operate at light load, and the fresh air mechanism 4 introduces outside air into the box body 2 and / or the heating mechanism 3, and then sends the cooled air into the incubator 1 through the guide structure 21 to cool the incubator 1.

[0157] Although the present invention has been described in detail above through general explanations, specific embodiments, and experiments, it will be apparent to those skilled in the art that modifications or improvements may be made to the present invention. Therefore, such modifications or improvements, without departing from the spirit of the present invention, are within the scope of protection claimed herein.

Claims

1. An incubation and cultivation device, characterized in that: include: Box (2); An incubator (1) is used to accommodate a sample and can be arranged in the box body (2), wherein the number of the incubator (1) is one or more; the incubator (1) comprises a first heating unit (16), and the first heating unit (16) is used to heat the sample in the incubator (1); A heating mechanism (3) is provided in the box (2), and the heating mechanism (3) is capable of heating the sample in the incubator (1); The box body (2) comprises a flow guiding structure (21), and the flow guiding structure (21) allows air to circulate between the heating mechanism (3) and the incubator (1).

2. The incubation and cultivation device according to claim 1, characterized in that: The air guide structure (21) comprises an air supply duct (211) and an air return duct (213); the heating mechanism (3), the air supply duct (211), the incubator (1) and the air return duct (213) are connected in sequence to form a loop.

3. The incubation and cultivation device according to claim 2, characterized in that: The air supply outlet end (212) of the air supply duct (211) is in communication with the first side (17) of the incubator (1), and the return air inlet end (215) of the return air duct (213) is in communication with the second side (18) of the incubator (1), wherein the first side (17) and the second side (18) are arranged opposite to each other.

4. The incubation and cultivation device according to claim 3, characterized in that: The box body (2) further comprises a first box wall (24) and a second box wall (25); the air supply duct (211) is arranged in the first box wall (24), and the air return duct (213) is arranged in the second box wall (25).

5. The incubation and cultivation device according to claim 4, characterized in that: The first box wall (24) and the second box wall (25) are arranged opposite to each other; and / or The incubator (1) is arranged between the first box wall (24) and the second box wall (25), and the first box wall (24) is arranged opposite to the first side (17) of the incubator (1), and the second side (18) of the incubator (1) is arranged opposite to the second box wall (25).

6. The incubation and cultivation device according to claim 3, characterized in that: The air supply outlet end (212) includes a plurality of air inlet holes (2121) arranged at intervals; and / or the return air inlet end (215) includes a plurality of air outlet holes (2151) arranged at intervals.

7. The incubation and cultivation device according to any one of claims 3 to 6, characterized in that: The air guide structure (21) further includes an air supply buffer portion (26) for buffering hot air and / or making the hot air evenly distributed, and the air supply duct (211) and the air supply outlet end (212) are connected via the air supply buffer portion (26); and / or The flow guiding structure (21) further comprises a return air buffer portion (27) for buffering air, and the return air duct (213) and the return air inlet end (215) are connected via the return air buffer portion (27).

8. The incubation and cultivation device according to claim 7, characterized in that: The air supply buffer portion (26) is disposed in the air supply duct (211); and / or The air supply buffer portion (26) is disposed adjacent to the air supply outlet end (212); and / or The return air buffer portion (27) is disposed in the return air duct (213); and / or The return air buffer portion (27) is arranged adjacent to the return air inlet end (215).

9. The incubation and cultivation device according to claim 7, characterized in that: The air supply buffer portion (26) comprises a first buffer frame (261), the first buffer frame (261) is provided with a first opening (265) and an air supply port (264), the first opening (265) is arranged opposite to the air supply outlet end (212), the air supply port (264) is communicated with the air supply duct (211), and the cross-sectional area of ​​the first opening (265) is greater than the cross-sectional area of ​​the air supply port (264); and / or The return air buffer portion (27) includes a second buffer frame (271), the second buffer frame (271) is provided with a second opening (275) and a return air outlet (274), the second opening (275) is arranged opposite to the return air inlet end (215), the return air outlet (274) is connected to the return air duct (213), and the cross-sectional area of ​​the second opening (275) is larger than the cross-sectional area of ​​the return air outlet (274).

10. The incubation and cultivation device according to claim 9, characterized in that: The first buffer frame encloses a first buffer space (262), and the first opening (265) and the air supply port (264) are both in communication with the first buffer space (262); The second buffer frame (271) encloses a second buffer space (272), and the second opening (275) and the return air port (274) are both in communication with the second buffer space (272).

11. The incubation and cultivation device according to claim 10, characterized in that: The air supply buffer portion (26) further includes a first partition portion (263), the first partition portion (263) being provided with a plurality of first vent holes (266), the first partition portion (263) dividing the first buffer space (262) into two connected spaces; and / or The return air buffer portion (27) further includes a second partition portion (273). A plurality of second vent holes (276) are provided on the second partition portion (273). The second partition portion (273) divides the second buffer space (272) into two connected spaces.

12. The incubation and cultivation device according to claim 4 or 5, characterized in that: The first box wall (24) includes a first inner plate (241) and a first outer plate (242) that are spaced apart, and the air supply duct (211) is formed between the first inner plate (241) and the first outer plate (242); and / or, The second box wall (25) comprises a second inner plate (251) and a second outer plate (252) which are spaced apart from each other. The return air duct (213) is formed between the second inner plate (251) and the second outer plate (252).

13. The incubation and cultivation device according to any one of claims 3, 5 and 6, characterized in that: Each of the incubators (1) is provided with at least one corresponding air supply outlet (212); and / or Each incubator (1) is provided with at least one corresponding return air inlet end (215).

14. The incubation and cultivation device according to claim 1, characterized in that: The box body (2) further comprises a partition (28), wherein the partition (28) is used to separate two adjacent incubators (1), and / or the partition (28) is used to separate the incubator (1) and the heating mechanism (3).

15. The incubation and cultivation device according to claim 14, characterized in that: The heating mechanism (3) comprises an air driving member (31), and the air driving member (31) is used to drive air to flow between the heating mechanism (3) and the incubator (1).

16. The incubation and cultivation device according to claim 15, characterized in that: An accommodating space (23) is formed between the partition (28) and the bottom (22) of the box body (2); the heating mechanism (3) is arranged in the accommodating space (23); and the accommodating space (23) is communicated with the flow guide structure (21).

17. The incubation and cultivation device according to claim 13, characterized in that: The incubator (1) comprises a first shell (15), the first shell (15) comprising a first side wall (151) and a second side wall (152) arranged opposite to each other, and the flow guide structure (21) is connected to the incubator (1) via the first side wall (151) and the second side wall (152).

18. The incubation and cultivation device according to claim 17, characterized in that: The first shell (15) further comprises a bottom wall (153), wherein the bottom wall (153) is provided with a plurality of first air holes (1531); and / or The first side wall (151) and the second side wall (152) are both provided with second air holes (1521), and the flow guide structure (21) is connected to the incubator (1) through the second air holes (1521).

19. The incubation and cultivation device according to claim 1, characterized in that: The incubation and cultivation device further comprises a control module, which is electrically connected to the heating mechanism (3) and the first heating unit (16).

20. The incubation and cultivation device according to any one of claims 1 to 6, characterized in that: The incubation and cultivation device further comprises a fresh air mechanism (4) connected to the box (2), wherein the fresh air mechanism (4) is used to filter air, and external air enters the box (2) and / or the heating mechanism (3) through the fresh air mechanism (4).

21. The incubation and cultivation device according to any one of claims 1 to 6, characterized in that: The heating mechanism (3) comprises a second shell (32) and a second heating unit, wherein the second heating unit is arranged in the second shell (32).

22. The incubation and cultivation device according to claim 21, characterized in that: The heating mechanism (3) further comprises a first temperature detection unit and / or a temperature protection unit arranged in the second shell (32).

23. The incubation and cultivation device according to any one of claims 1 to 6, characterized in that: The incubator (1) further comprises a second temperature detection unit, which is used to detect the temperature inside the incubator (1).

24. The incubation and cultivation device according to any one of claims 1 to 6, characterized in that: The incubation and cultivation device further comprises a heat dissipation mechanism (5), and the heat dissipation mechanism (5) is used to dissipate heat for the heating mechanism (3).

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