RNA (Ribonucleic Acid) metabolism redissolution extraction device

By designing a card sleeve and card block structure to stabilize the RNA tube, and combining it with an electric push rod and liquid delivery system, the problem of tipping caused by unstable RNA tubes is solved, achieving accurate and stable RNA extraction.

CN223445509UActive Publication Date: 2025-10-17FOURTH MILITARY MEDICAL UNIVERSITY
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Patent Information

Application Number
CN202421853991.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-08-02
Publication Date
2025-10-17
Estimated Expiration
2034-08-02

AI Technical Summary

Technical Problem

The RNA tube in the existing RNA extraction device is not placed firmly and is prone to tipping over when the liquid is injected, resulting in inaccurate extraction.

Method used

An RNA metabolic reconstitution and extraction device was designed. The RNA tube was stabilized by a sleeve and block structure, and an electric push rod and liquid delivery system were used to accurately inject the RNA into the tube. The rubber inner sleeve was used to protect the tube surface to ensure accurate liquid injection.

Benefits of technology

The RNA tube can be stably installed to avoid tipping, which improves the accuracy and stability of liquid extraction and ensures the reliability of RNA extraction.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of RNA, and discloses an RNA metabolism redissolution extraction device which comprises a workbench, vertical plates are fixedly connected to the two sides of the top end of the workbench respectively, a transverse plate is fixedly connected between the two vertical plates, a liquid storage tank is installed at the top end of the transverse plate, a pump body and a liquid injection opening are installed at the top end of the liquid storage tank, and the pump body and the liquid injection opening are communicated through a pipeline. The liquid injection opening is located in one side of the pump body, the liquid pumping end of the pump body is fixedly connected with a connecting pipe, the connecting pipe penetrates into the liquid storage box, a liquid discharging pipe of the pump body is fixedly connected with a liquid discharging pipe, and the end, away from the pump body, of the liquid discharging pipe is fixedly connected with a transfer box. According to the technical scheme, the clamping sleeve is sleeved outside the RNA carrying tube, then the RNA carrying tube is inserted into the limiting groove in the supporting plate, and the clamping blocks on the two sides of the clamping sleeve are clamped into the clamping grooves, so that the RNA carrying tube can be stably mounted through the matching of the structures, and the phenomenon of toppling during liquid injection is avoided.
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Description

TECHNICAL FIELD

[0001] The utility model relates to RNA technical field, concretely is a kind of RNA metabolism redissolving extraction device. BACKGROUND

[0002] Ribonucleic acid (abbreviation RNA) exists in the genetic information carrier of biological cell and part virus, virus-like. RNA is long-chain molecule by ribonucleotide condensation phosphate diester bond. A ribonucleotide molecule is composed of phosphate, ribose and base. The base of RNA mainly has four, namely A (adenine), G (guanine), C (cytosine), U (uracil), and U (uracil) replaces T (thymine) in DNA. The main role of ribonucleic acid in vivo is to guide the synthesis of protein.

[0003] The patent document with the published announcement number CN220788605U has disclosed an RNA redissolving extraction device, which belongs to the technical field of RNA extraction, and comprises a base, a placing seat and a rack arranged on the top of the base, a mounting frame arranged on the placing seat and a plurality of RNA carriers arranged on the mounting frame. A liquid storage tray is arranged above the RNA carriers on the rack. An adjusting mechanism for driving the liquid storage tray to move up and down is arranged on the rack. A liquid storage tank is arranged, and a liquid guide hose is arranged on the liquid storage tank and communicates with the liquid storage tray. A liquid guide pump is arranged on the liquid guide hose. A plurality of liquid storage tubes matched with the RNA carriers are arranged at the bottom of the liquid storage tray. According to the different number of RNA carriers, the solution is delivered to the liquid storage tubes above the RNA carriers through the quantitative mechanism, and then the solution is injected into the RNA carriers through the liquid injection pipe, so that the sample adding amount in each RNA carrier can be accurately controlled, and the sample adding operation of multiple groups of RNA carriers is facilitated.

[0004] The above-mentioned patent cannot guarantee the stability of the carrier tube during actual use, and the liquid injected into the carrier tube will produce a certain impact force on the carrier tube, which is easy to cause the carrier tube to fall over. Therefore, a RNA metabolism redissolving extraction device is needed. UTILITY MODEL CONTENT

[0005] The utility model aims at providing a RNA metabolism redissolving extraction device, which solves the problems raised in the background art.

[0006] The embodiment of the application provides a RNA metabolism reconstitution extraction device, which comprises a workbench, vertical plates are fixedly connected to the top of the workbench, a horizontal plate is fixedly connected between the two vertical plates, a liquid storage tank is installed at the top of the horizontal plate, a pump body and a liquid injection port are installed at the top of the liquid storage tank, the liquid injection port is located on one side of the pump body, a connecting pipe is fixedly connected to the liquid extraction end of the pump body, the connecting pipe penetrates into the inside of the liquid storage tank, a liquid discharge pipe is fixedly connected to the pump body, a transfer box is fixedly connected to the end of the liquid discharge pipe away from the pump body, a liquid injection pipe is threadedly connected to the bottom of the transfer box, an installation groove is formed in the front wall of the workbench, an electric push rod is installed in the installation groove, the output shaft of the electric push rod penetrates into the inside of the workbench and is fixedly connected with a supporting plate, two clamping grooves and a limiting groove are formed in the top of the supporting plate, the limiting groove is located between the two clamping grooves, an RNA loading tube is clamped in the limiting groove, a clamping sleeve is arranged outside the RNA loading tube, clamping blocks are fixedly connected to the two sides of the clamping sleeve, and the clamping blocks are clamped in the clamping grooves.

[0007] In use, first, the clamping sleeve is arranged outside the RNA loading tube, then the RNA loading tube is inserted into the limiting groove on the supporting plate, the clamping blocks on the two sides of the clamping sleeve are clamped into the clamping grooves, the RNA loading tube is stably installed through cooperation of the above structures, then the electric push rod pushes the RNA loading tube upwards until the bottom of the liquid injection pipe, the pump body can draw the liquid in the liquid storage tank into the inside of the transfer box through the connecting pipe and the liquid discharge pipe, then the liquid in the transfer box enters the inside of the liquid injection pipe, and finally the liquid injection pipe injects the liquid into the inside of the RNA loading tube, and the solution extraction is completed.

[0008] Optionally, the clamping groove and the limiting groove are communicated.

[0009] Through the above technical scheme, the clamping blocks can be normally clamped into the clamping grooves.

[0010] Optionally, a rubber inner sleeve is fixedly attached to the inner wall of the clamping sleeve.

[0011] Through the above technical scheme, the surface of the RNA loading tube can be prevented from being abraded by the clamping sleeve.

[0012] Optionally, a valve is installed on the liquid injection pipe.

[0013] Through the above technical scheme, the precision of the extracted liquid can be improved.

[0014] Optionally, the liquid injection pipe and the RNA loading tube are symmetrically arranged.

[0015] Through the above technical scheme, the liquid can be accurately injected into the inside of the RNA loading tube.

[0016] Optionally, the bottom end of the workbench is fixedly connected with a support column at each corner.

[0017] By adopting the above technical scheme, the workbench can be stably supported.

[0018] Optionally, the top end of the liquid injection port is provided with a sealing cover.

[0019] By adopting the above technical scheme, the liquid injection port can be sealed when not in use.

[0020] Optionally, the circular slot of the limiting groove is adapted to the diameter of the RNA carrier tube.

[0021] By adopting the above technical scheme, the stability of the installation of the RNA carrier tube can be improved.

[0022] Compared with the prior art, the technical scheme of the present application has the following advantages:

[0023] The technical scheme of the present application first fits the sleeve on the outside of the RNA carrier tube, then inserts the RNA carrier tube into the limiting groove on the support plate, and the clamping blocks on both sides of the sleeve are clamped into the interior of the clamping groove. Through the cooperation of the above structures, the RNA carrier tube can be stably installed, and the phenomenon of tilting during liquid injection can be avoided. BRIEF DESCRIPTION OF DRAWINGS

[0024] Other features, objects and advantages of the present application will become more apparent from the following detailed description of non-limiting embodiments, with reference to the accompanying drawings:

[0025] Figure 1 FIG. 1 is a schematic diagram of the overall structure of the RNA metabolism reconstitution and extraction device of the present application;

[0026] Figure 2 FIG. 2 is a schematic diagram of the side view structure of the RNA metabolism reconstitution and extraction device of the present application;

[0027] Figure 3 FIG. 3 is an enlarged schematic diagram of the A area structure of the RNA metabolism reconstitution and extraction device of the present application;

[0028] Figure 4 FIG. 4 is a schematic diagram of the structure of the sleeve of the RNA metabolism reconstitution and extraction device of the present application.

[0029] In the figure: 1, liquid storage tank; 2, liquid discharge pipe; 3, pump body; 4, liquid injection port; 5, horizontal plate; 6, vertical plate; 7, support column; 8, valve; 9, transfer box; 10, liquid injection pipe; 11, workbench; 12, electric push rod; 13, mounting groove; 14, connecting pipe; 15, sleeve; 16, support plate; 17, clamping block; 18, RNA carrier tube; 19, clamping groove; 20, rubber inner sleeve; 21, limiting groove. DETAILED DESCRIPTION

[0030] Referring to Figures 1-4 The utility model provides a technical scheme: a kind of RNA metabolism reconstitution extraction device, including workbench 11, the top of workbench 11 Both sides are fixedly connected with vertical plate 6, two vertical plate 6 are fixedly connected with crosspiece 5, and the top of crosspiece 5 is installed with liquid storage tank 1, and the top of liquid storage tank 1 is installed with pump body 3 and liquid injection port 4, and liquid injection port 4 is located at one side of pump body 3, and the liquid suction end of pump body 3 is fixedly connected with connecting pipe 14, and connecting pipe 14 is arranged to the inside of liquid storage tank 1, and the liquid discharge pipe of pump body 3 is fixedly connected with liquid discharge pipe 2, and the end of liquid discharge pipe 2 away from pump body 3 is fixedly connected with transfer box 9, and the bottom of transfer box 9 is threadedly connected with liquid injection pipe 10, and the front wall of workbench 11 is provided with installation groove 13, and electric push rod 12 is installed in the inside of installation groove 13, and the output shaft of electric push rod 12 is arranged to the inside of workbench 11 and is fixedly connected with support plate 16, and the top of support plate 16 is provided with two clamping grooves 19 and limit groove 21, and limit groove 21 is located between two clamping grooves 19, and RNA carrier tube 18 is clampedly connected in the inside of limit groove 21, and the outside of RNA carrier tube 18 is equipped with sleeve 15, and the two sides of sleeve 15 are fixedly connected with clamping block 17, and clamping block 17 is clamped in the inside of clamping groove 19.

[0031] In the technical scheme of the utility model, as Figure 1 Indicated, clamping groove 19 and limit groove 21 are communicated;It is favorable for clamping block 17 can normally be inserted into the inside of clamping groove 19.

[0032] In the technical scheme of the utility model, as Figure 4 Indicated, the inner wall of sleeve 15 is pasted and fixed with rubber inner sleeve 20;It can avoid that the surface of RNA carrier tube 18 is abraded by sleeve 15.

[0033] In the technical scheme of the utility model, as Figure 1 Indicated, valve 8 is installed on liquid injection pipe 10;It is favorable to improve the precision of extracting liquid.

[0034] In the technical scheme of the utility model, as Figure 1 Indicated, liquid injection pipe 10 and RNA carrier tube 18 are symmetrically arranged;It is favorable to make liquid accurately inject into the inside of RNA carrier tube 18.

[0035] In the technical scheme of the utility model, as Figure 1 Indicated, the four corners of the bottom of workbench 11 are fixedly connected with support column 7;It is favorable to stably support workbench 11.

[0036] In the technical scheme of the utility model, as Figure 1As shown, the top cover of the liquid injection port 4 is provided with a sealing cover; the liquid injection port 4 can be sealed when not in use.

[0037] In the technical solution of the present utility model, Figure 3 As shown, the diameter of the circular slot of the limiting slot 21 is adapted to the diameter of the RNA carrier tube 18 , which is beneficial to improving the installation stability of the RNA carrier tube 18 .

[0038] During use, the ferrule 15 is first sleeved on the outside of the RNA carrier tube 18, and then the RNA carrier tube 18 is inserted into the limiting groove 21 on the support plate 16. The blocks 17 on both sides of the ferrule 15 are then inserted into the inside of the card groove 19. Through the cooperation of the above structures, the RNA carrier tube 18 can be firmly installed, and then the RNA carrier tube 18 is pushed up by the electric push rod 12 until it is located at the bottom of the injection tube 10. The pump body 3 can, under the action of the connecting tube 15 and the discharge tube 2, draw the liquid inside the liquid storage tank 1 into the interior of the transfer box 9, and then enter the interior of the injection tube 10 from the transfer box 9, and then the liquid is injected into the interior of the RNA carrier tube 18 by the injection tube 10 to complete the extraction of the solution.

[0039] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art will be able to modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein with equivalents. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention shall be included within the scope of protection of the present invention.

Claims

1. An RNA metabolic redissolution and extraction device, characterized by: The invention comprises a workbench (11), wherein both sides of the top of the workbench (11) are fixedly connected with vertical plates (6), a horizontal plate (5) is fixedly connected between the two vertical plates (6), a liquid storage tank (1) is installed at the top of the horizontal plate (5), a pump body (3) and a liquid injection port (4) are installed at the top of the liquid storage tank (1), the liquid injection port (4) is located on one side of the pump body (3), the liquid extraction end of the pump body (3) is fixedly connected with a connecting pipe (14), the connecting pipe (14) is passed through the interior of the liquid storage tank (1), the discharge pipe of the pump body (3) is fixedly connected with a discharge pipe (2), the end of the discharge pipe (2) away from the pump body (3) is fixedly connected with a transfer box (9), and the bottom end of the transfer box (9) is threadedly connected with the liquid injection pipe ( 10), the front wall of the workbench (11) is provided with a mounting groove (13), an electric push rod (12) is installed inside the mounting groove (13), the output shaft of the electric push rod (12) is passed through the inside of the workbench (11) and is fixedly connected to a support plate (16), the top of the support plate (16) is provided with two card slots (19) and a limit slot (21), the limit slot (21) is located between the two card slots (19), the inside of the limit slot (21) is engaged with an RNA carrier tube (18), the outside of the RNA carrier tube (18) is provided with a card sleeve (15), both sides of the card sleeve (15) are fixedly connected with a card block (17), and the card block (17) is engaged with the inside of the card slot (19).

2. The RNA metabolic redissolution and extraction device according to claim 1, characterized in that: The clamping slot (19) and the limiting slot (21) are connected.

3. The RNA metabolic redissolution and extraction device according to claim 1, characterized in that: A rubber inner sleeve (20) is adhered and fixed to the inner wall of the clamping sleeve (15).

4. The RNA metabolic redissolution and extraction device according to claim 1, characterized in that: A valve (8) is installed on the liquid injection pipe (10).

5. The RNA metabolic redissolution and extraction device according to claim 1, characterized in that: The liquid injection tube (10) and the RNA carrier tube (18) are symmetrically arranged up and down.

6. The RNA metabolic redissolution and extraction device according to claim 1, characterized in that: The four corners of the bottom end of the workbench (11) are fixedly connected with support columns (7).

7. The RNA metabolic redissolution and extraction device according to claim 1, characterized in that: The top end cover of the liquid injection port (4) is provided with a sealing cover.

8. The RNA metabolic redissolution and extraction device according to claim 1, characterized in that: The diameter of the circular notch of the limiting groove (21) is adapted to the diameter of the RNA carrier tube (18).

Citation Information

Patent Citations

  • RNA (Ribonucleic Acid) redissolving and extracting device

    CN220788605U