Material mixing device of western blot instrument

Abstract

The utility model provides a material mixing device of a western blot instrument. The western blot material mixing device comprises a western blot material mixing device body, a vibrating plate is arranged on the western blot material mixing device body, a placing groove is formed in the top of the vibrating plate, a U-shaped mounting groove is further formed in the top of the vibrating plate, two rotating shafts are rotatably mounted on the inner wall of the bottom of the U-shaped mounting groove, and the two rotating shafts are arranged on the bottom of the U-shaped mounting groove. And the two rotating shafts are located on the two sides of the containing groove correspondingly, the two rotating shafts are fixedly sleeved with blocking pieces located above the vibration plate, the two rotating shafts are fixedly sleeved with gears located in the U-shaped mounting groove, and two fixing bases are fixedly mounted on the inner wall of the bottom of the U-shaped mounting groove. The western blot instrument material mixing device provided by the utility model has the advantages that the material tray can be easily placed by a single person, the operation is simple, and the use is convenient.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of protein imprinter, especially to a protein imprinter material mixing device. BACKGROUND

[0002] The protein imprinter is a device for screening and diagnosing different pathogenic sources causing infectious diseases in clinical diagnosis, and its principle is to color the cell or biological tissue sample treated by gel electrophoresis through specific antibodies, and to obtain the information of the expression of specific proteins in the analyzed cell or tissue by analyzing the location and depth of coloring. The protein imprinter is provided with a material mixing device for fully vibrating and mixing the antibodies and target proteins.

[0003] The Chinese utility model patent with application number 202320077343.2 proposes a protein imprinter material mixing device, which belongs to the technical field of protein imprinter. It includes a fixed seat and a vibrating plate. The vibrating plate is arranged directly above the fixed seat. A second rectangular groove is formed at the top of the fixed seat. A vibrating device is arranged inside the second rectangular groove. Guide devices are arranged inside the second rectangular groove on both sides. First springs are uniformly fixed and installed on the top of the fixed seat on both sides. A turning device is arranged between the clamping devices on the same side of the vibrating plate. When the eccentric wheel in rotation pushes the support rod to vibrate up and down, the rubber ring and the U-shaped rubber pad are in contact with each other, thereby reducing the vibration noise emitted by the eccentric wheel and the support rod. A soundproof cover is arranged outside the motor, the first pulley, the belt, and the second pulley, thereby reducing the noise emitted by the motor and the noise produced by the rotation of the belt and the pulley, and thereby reducing the working noise of the entire protein imprinter.

[0004] Although the utility model patent can limit the material box placed in the vibrating plate by arranging two turning devices (each turning device includes a turning plate, multiple cylinders, multiple circular blocks, multiple second springs, etc.), it can avoid the material box from separating from the placing groove. However, before placing the material box, the relevant staff needs to turn the two turning plates on both sides with both hands and hold them. Another person needs to place the material box into the placing groove. The operation is not convenient, and more personnel are occupied. Therefore, it is necessary to provide a new protein imprinter material mixing device to solve the above technical problems. UTILITY MODEL CONTENTS

[0005] The utility model solves the technical problem of providing a protein imprinter material mixing device that can be easily placed by a single person, which is simple to operate and convenient to use.

[0006] In order to solve the above technical problems, the protein blotting instrument material mixing device comprises a protein blotting instrument material mixing device body, a vibration plate is arranged on the protein blotting instrument material mixing device body, a placing groove is formed in the top of the vibration plate, a U-shaped mounting groove is also formed in the top of the vibration plate, two rotating shafts are rotatably installed on the inner wall of the bottom of the U-shaped mounting groove, the two rotating shafts are located on the two sides of the placing groove respectively, a baffle is fixedly installed above the vibration plate on the two rotating shafts, a gear is fixedly installed in the U-shaped mounting groove on the two rotating shafts, two fixed seats are fixedly installed on the inner wall of the bottom of the U-shaped mounting groove, a sliding rod is slidably installed through the two fixed seats, a rack is fixedly installed on the end of the sliding rod close to the corresponding baffle, the two racks are engaged with the corresponding gears, a circular end plate is fixedly installed on the end of the sliding rod away from the corresponding baffle, a traction rope is fixedly installed on the two circular end plates, two operation hand plates are slidably installed on the front side outer wall of the vibration plate, the two operation hand plates extend into the U-shaped mounting groove at one end, the ends of the two traction ropes close to each other are fixedly connected with the corresponding operation hand plates at one end in the U-shaped mounting groove, a tension spring is sleeved on the two sliding rods, one end of the tension spring is fixedly connected with the fixed seat, and the other end is fixedly connected with the circular end plate.

[0007] Preferably, a protective cover groove is formed in the top of the vibration plate, the protective cover groove is in communication with the U-shaped mounting groove, a U-shaped protective cover is fixedly installed in the protective cover groove, and the top of the U-shaped protective cover is in the same horizontal plane as the top of the vibration plate.

[0008] Preferably, two guide pulleys are fixedly installed in the U-shaped mounting groove, and the two traction ropes are located in the wheel grooves of the two guide pulleys.

[0009] Preferably, two advancing limiting blocks are fixedly installed in the U-shaped mounting groove, and the ends of the two racks away from the corresponding sliding rods are in contact with the two advancing limiting blocks respectively.

[0010] Preferably, a retreating limiting block is fixedly installed on the top of each of the two sliding rods.

[0011] Compared with the related art, the protein blotting instrument material mixing device has the following beneficial effects:

[0012] This utility model provides a material mixing device for a protein blot instrument. It is configured with two rotating shafts, two baffles, two gears, two sliding rods, two racks, two tension springs, two traction ropes, and two operating handplates. In use, the index finger and thumb of one hand simultaneously pinch the two operating handplates, causing them to move towards each other. This rotates the two baffles to the sides, preventing them from obstructing the placement of the material tray. After placing the material tray in the slot on the vibrating plate with the other hand, releasing the two operating handplates allows the two baffles to automatically rotate back, securing the material tray reliably. This device can be easily operated by a single person, offering advantages such as ease of use and simple operation. Attached Figure Description

[0013] Figure 1 A schematic diagram of a preferred embodiment of the material mixing device for a protein blotting apparatus provided by this utility model;

[0014] Figure 2 for Figure 1 The diagram shows the structure of the material mixing device of the protein blot instrument after the U-shaped protective cover has been removed.

[0015] Figure 3 for Figure 2 The enlarged schematic diagram of part A shown below;

[0016] Figure 4 A top sectional view of a preferred embodiment of the material mixing device for a protein blotting apparatus provided by this utility model;

[0017] Figure 5 for Figure 4 The enlarged schematic diagram of section B is shown below;

[0018] Figure 6 This is a schematic diagram of the connection structure of components such as gears, racks, sliding rods, and fixed seats in this utility model;

[0019] Figure 7 This is a schematic diagram of the assembly of the traction rope and the guide pulley in this utility model.

[0020] The following are the labels in the diagram: 1. Vibrating plate; 2. U-shaped protective cover; 3. Rotating shaft; 4. Baffle; 5. Gear; 6. Fixed base; 7. Sliding rod; 8. Rack; 9. Circular end plate; 10. Tension spring; 11. Traction rope; 12. Guide pulley; 13. Operating hand panel; 101. Protective cover groove; 102. U-shaped mounting groove. Detailed Implementation

[0021] The present invention will be further described below with reference to the accompanying drawings and embodiments.

[0022] Please refer to the following: Figures 1-7The material mixing device for a protein blotting instrument includes: a main body for the material mixing device, the main components of which adopt the conventional design of existing material mixing devices for protein blotting instruments. A vibrating plate 1 is provided on the main body, and a placement groove is opened on the top of the vibrating plate 1. Unlike existing technologies, a U-shaped mounting groove 102 is also opened on the top of the vibrating plate 1, and the placement groove is located within the U-shaped mounting groove 102. Two rotating shafts 3 are rotatably mounted on the bottom inner wall of the U-shaped mounting groove 102, with the top ends of both rotating shafts 3 extending above the vibrating plate 1. The two rotating shafts 3 are located on opposite sides of the placement groove, and baffles 4 are fixedly sleeved on both rotating shafts 3 above the vibrating plate 1. The baffles 4 are used to block the material tray containing the antibody and target protein mixture. Initially, the baffles 4 are positioned as follows: Figure 1 As shown, gears 5 are fixedly fitted onto both rotating shafts 3 within U-shaped mounting grooves 102. Two fixed seats 6 are fixedly installed on the bottom inner wall of the U-shaped mounting groove 102. Sliding rods 7 are slidably installed through and on each of the two fixed seats 6. Racks 8 are fixedly installed on the ends of the two sliding rods 7 near the corresponding baffles 4. Both racks 8 mesh with the corresponding gears 5. A clamping block is fixedly installed on the outer wall of the rack 8 away from the gears 5. The clamping block is slidably connected to the inner wall of the U-shaped mounting groove 102. Circular end plates 9 are fixedly installed on the ends of the two sliding rods 7 away from the corresponding baffles 4. Traction ropes 11 are fixedly installed on both circular end plates 9. Two operating hand plates 13 are slidably installed on the front outer wall of the vibrating plate 1. Specifically, two square sliding openings communicating with the U-shaped mounting groove 102 are opened on the front outer wall of the vibrating plate 1. The two operating hand plates 13 are slidably installed in the corresponding square sliding openings. One end of each operating hand plate 13 is fixedly installed in the square sliding opening. Extending into the U-shaped mounting groove 102, the ends of the two traction ropes 11 that are close to each other are fixedly connected to the corresponding operating hand plates 13 located at one end of the U-shaped mounting groove 102. By pinching the two operating hand plates 13 with the index finger and thumb, the two operating hand plates 13 move towards each other. The two operating hand plates 13 drive the corresponding traction ropes 11 to move. The traction ropes 11 drive the sliding rod 7 to move backward, and the sliding rod 7 drives the rack 8 to move. During the backward movement of the rack 8, it will drive the gear 5 to rotate in the opposite direction, thereby causing the rotating shaft 3 to rotate in the opposite direction. Under the drive of the two rotating shafts 3, the two baffles 4 will rotate to the sides respectively and no longer block the top of the mounting groove. Each of the two sliding rods 7 is fitted with a tension spring 10. One end of the tension spring 10 is fixedly connected to the fixed seat 6, and the other end is fixedly connected to the circular end plate 9. During the process of the traction ropes 11 pulling the sliding rods 7 backward, the tension spring 10 will be stretched. After releasing the two operating hand plates 13, the tension of the tension spring 10 will cause the sliding rods 7 to return to their original position forward.

[0023] In the embodiment, in order to protect the components in the U-shaped mounting groove 102, a protective cover groove 101 is formed in the top of the vibration plate 1, the protective cover groove 101 is communicated with the U-shaped mounting groove 102, a U-shaped protective cover 2 is fixedly installed in the protective cover groove 101, the top of the U-shaped protective cover 2 is at the same horizontal plane with the top of the vibration plate 1, two avoiding holes are formed in the U-shaped protective cover 2, and the two rotating shafts 3 are all penetrated through the corresponding avoiding holes and movably connected with the inner walls of the corresponding avoiding holes.

[0024] In the embodiment, in order to avoid that the traction rope 11 is subjected to excessive friction and reduce the resistance when the traction rope 11 moves, two guide pulleys 12 are fixedly installed in the U-shaped mounting groove 102, and the two traction ropes 11 are located in the wheel grooves of the two guide pulleys 12.

[0025] In the embodiment, in order to limit the stroke of the forward movement of the rack 8, two forward limiting blocks are fixedly installed in the U-shaped mounting groove 102, and the ends of the two racks 8, away from the corresponding sliding rods 7, are in contact with the two forward limiting blocks, respectively.

[0026] In the embodiment, in order to limit the stroke of the backward movement of the rack 8, the top of each of the two sliding rods 7 is fixedly installed with a backward limiting block, and when the backward limiting block is in contact with the corresponding fixed seat 6, the rotating shaft 3 is rotated by 90°.

[0027] The working principle of the protein blotting instrument material mixing device is as follows:

[0028] When in use, the protein blotting instrument material mixing device is fixedly installed in the protein blotting instrument, when the antibody and the target protein are mixed, the index finger and the thumb are used to pinch the two operation hand plates 13 respectively, the two operation hand plates 13 are moved towards each other, the operation hand plate 13 drives the traction rope 11 to move, the two traction ropes 11 pull the corresponding sliding rods 7 to retreat, the two tension springs 10 are stretched, the two racks 8 retreat along the corresponding sliding rods 7, drive the two gears 5 to rotate, since the two racks 8 are oppositely arranged, the left gear 5 rotates counterclockwise, and the right gear 5 rotates clockwise, the two gears 5 drive the corresponding rotating shafts 3 to rotate, the rotating shaft 3 drives the baffle 4 to rotate, so that the two baffles 4 rotate to the two sides respectively, when the retreat limiting block on the sliding rod 7 abuts against the corresponding fixed seat 6, the sliding rod 7 cannot retreat further, at this time, the baffle 4 completes 90° rotation, and the two baffles 4 are not blocked above the placing groove, but are located at the two sides of the installation groove, under the condition that the two operation hand plates 13 are not reset, the other hand places the material disc containing the antibody and the target protein into the placing groove on the vibration plate 1, and then the two operation hand plates 13 are loosened, under the tension of the two tension springs 10, the two sliding rods 7 are reset forward, the two racks 8 move forward along the sliding rods 7, drive the corresponding gears 5 to rotate reversely, so that the two baffles 4 are finally reset and are blocked above the installation groove, and the two baffles 4 block the material disc and prevent the material disc from sliding out in the vibration process.

[0029] Compared with the related art, the protein blotting instrument material mixing device has the following beneficial effects:

[0030] The protein blotting instrument material mixing device is provided with two rotating shafts 3, two baffles 4, two gears 5, two sliding rods 7, two racks 8, two tension springs 10, two traction ropes 11 and two operation hand plates 13, when in use, the index finger and the thumb of one hand pinch the two operation hand plates 13 simultaneously, when the two operation hand plates 13 move towards each other, the two baffles 4 can be driven to rotate to the two sides respectively, so that the two baffles 4 do not block the placement of the material disc, after the other hand places the material disc in the placing groove on the vibration plate 1, the two baffles 4 can automatically rotate and are blocked above the material disc, so that the material disc is reliably limited, and one person can easily complete the operation, and the whole device has the advantages of convenient use and simple operation.

[0031] The above description is only an embodiment of the utility model, and does not limit the patent range of the utility model, and any equivalent structure or equivalent process conversion in the utility model specification and the attached drawings, or direct or indirect application in other related technical fields, is also included in the patent protection range of the utility model.

Claims

1. A protein blotting apparatus material mixing device, comprising a protein blotting apparatus material mixing device body, a vibration plate is arranged on the protein blotting apparatus material mixing device body, and a placing groove is formed in the top of the vibration plate, characterized in that, The top of the vibrating plate is also provided with a U-shaped mounting groove, two rotating shafts are rotatably installed on the inner wall of the bottom of the U-shaped mounting groove, the two rotating shafts are located on the two sides of the placing groove respectively, a baffle is fixedly installed above the vibrating plate on each of the two rotating shafts, a gear is fixedly installed in the U-shaped mounting groove on each of the two rotating shafts, two fixed seats are fixedly installed on the inner wall of the bottom of the U-shaped mounting groove, a sliding rod is slidably installed through the two fixed seats, a rack is fixedly installed on the end of each of the two sliding rods close to the corresponding baffle, the two racks are engaged with the corresponding gears, a circular end plate is fixedly installed on the end of each of the two sliding rods away from the corresponding baffle, a traction rope is fixedly installed on each of the two circular end plates, two operation hand plates are slidably installed on the front outer wall of the vibrating plate, the two operation hand plates extend into the U-shaped mounting groove at one end, the ends of the two traction ropes close to each other are fixedly connected with the corresponding operation hand plates at one end in the U-shaped mounting groove, a tension spring is sleeved on each of the two sliding rods, one end of the tension spring is fixedly connected with the fixed seat, and the other end is fixedly connected with the circular end plate.

2. The Western blot apparatus material mixing device of claim 1, wherein, The top of the vibrating plate is also provided with a U-shaped mounting groove, two rotating shafts are rotatably installed on the inner wall of the bottom of the U-shaped mounting groove, the two rotating shafts are located on the two sides of the placing groove respectively, a baffle is fixedly installed above the vibrating plate on each of the two rotating shafts, a gear is fixedly installed in the U-shaped mounting groove on each of the two rotating shafts, two fixed seats are fixedly installed on the inner wall of the bottom of the U-shaped mounting groove, a sliding rod is slidably installed through the two fixed seats, a rack is fixedly installed on the end of each of the two sliding rods close to the corresponding baffle, the two racks are engaged with the corresponding gears, a circular end plate is fixedly installed on the end of each of the two sliding rods away from the corresponding baffle, a traction rope is fixedly installed on each of the two circular end plates, two operation hand plates are slidably installed on the front outer wall of the vibrating plate, the two operation hand plates extend into the U-shaped mounting groove at one end, the ends of the two traction ropes close to each other are fixedly connected with the corresponding operation hand plates at one end in the U-shaped mounting groove, a tension spring is sleeved on each of the two sliding rods, one end of the tension spring is fixedly connected with the fixed seat, and the other end is fixedly connected with the circular end plate.

3. The Western blot apparatus material mixing device of claim 1, wherein, The top of the vibrating plate is also provided with a U-shaped mounting groove, two rotating shafts are rotatably installed on the inner wall of the bottom of the U-shaped mounting groove, the two rotating shafts are located on the two sides of the placing groove respectively, a baffle is fixedly installed above the vibrating plate on each of the two rotating shafts, a gear is fixedly installed in the U-shaped mounting groove on each of the two rotating shafts, two fixed seats are fixedly installed on the inner wall of the bottom of the U-shaped mounting groove, a sliding rod is slidably installed through the two fixed seats, a rack is fixedly installed on the end of each of the two sliding rods close to the corresponding baffle, the two racks are engaged with the corresponding gears, a circular end plate is fixedly installed on the end of each of the two sliding rods away from the corresponding baffle, a traction rope is fixedly installed on each of the two circular end plates, two operation hand plates are slidably installed on the front outer wall of the vibrating plate, the two operation hand plates extend into the U-shaped mounting groove at one end, the ends of the two traction ropes close to each other are fixedly connected with the corresponding operation hand plates at one end in the U-shaped mounting groove, a tension spring is sleeved on each of the two sliding rods, one end of the tension spring is fixedly connected with the fixed seat, and the other end is fixedly connected with the circular end plate.

4. The protein blotter material mixing device of claim 1, wherein, The top of the vibrating plate is also provided with a U-shaped mounting groove, two rotating shafts are rotatably installed on the inner wall of the bottom of the U-shaped mounting groove, the two rotating shafts are located on the two sides of the placing groove respectively, a baffle is fixedly installed above the vibrating plate on each of the two rotating shafts, a gear is fixedly installed in the U-shaped mounting groove on each of the two rotating shafts, two fixed seats are fixedly installed on the inner wall of the bottom of the U-shaped mounting groove, a sliding rod is slidably installed through the two fixed seats, a rack is fixedly installed on the end of each of the two sliding rods close to the corresponding baffle, the two racks are engaged with the corresponding gears, a circular end plate is fixedly installed on the end of each of the two sliding rods away from the corresponding baffle, a traction rope is fixedly installed on each of the two circular end plates, two operation hand plates are slidably installed on the front outer wall of the vibrating plate, the two operation hand plates extend into the U-shaped mounting groove at one end, the ends of the two traction ropes close to each other are fixedly connected with the corresponding operation hand plates at one end in the U-shaped mounting groove, a tension spring is sleeved on each of the two sliding rods, one end of the tension spring is fixedly connected with the fixed seat, and the other end is fixedly connected with the circular end plate.

5. The protein blotter material mixing device of claim 4, wherein, ​

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