Propylthiouracil preparation reaction device

Abstract

The utility model discloses a propylthiouracil preparation reaction device which comprises a preparation reaction kettle, a first preparation barrel, an air inlet pump and a second preparation barrel, a water pump is arranged in the first preparation barrel, the output end of the water pump is fixedly connected with a first water inlet pipe, one end of the first water inlet pipe is fixedly connected with a Venturi pipe, and the other end of the first water inlet pipe is fixedly connected with a second water inlet pipe. A second water inlet pipe is fixedly connected to the interior of the second preparation barrel, a liquid inlet, a connecting thin neck and a liquid outlet are sequentially formed in a Venturi tube, and a liquid inlet cavity is formed in the upper side wall of the connecting thin neck; the upper side wall of the preparation reaction kettle is fixedly connected with a gas outlet connecting pipe, and the upper end of the gas outlet connecting pipe is fixedly connected with a gas outlet valve. According to the utility model, the venturi tube can enable the first preparation and the second preparation to be quickly and uniformly mixed, and a large number of fine bubbles are generated in the mixed liquid, so that the reaction rate and mass transfer efficiency of the propylthiouracil preparation can be effectively improved, and the mixing effect is effectively improved.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical processing technology, and in particular to a reaction apparatus for propylthiouracil formulation. Background Technology

[0002] Propylthiouracil (PTU) is a thioamide antithyroid drug whose main function is to inhibit thyroid peroxidase and block the production of thyroid hormones. It is mainly used to treat hyperthyroidism in adults.

[0003] However, the mixing devices in the reaction equipment currently used for processing propylthiouracil formulations on the market are ineffective and make it difficult to fully mix propylthiouracil, which is not conducive to ensuring a complete reaction in the processing of propylthiouracil formulations. Utility Model Content

[0004] The purpose of this invention is to at least solve one of the technical problems existing in the prior art, and to provide a propylthiouracil formulation reaction device. The device is equipped with a Venturi tube, a first formulation tank and a second formulation tank. A water pump can introduce the first formulation in the first formulation tank into the liquid inlet through a first water inlet pipe. The first formulation flows through the connecting neck and can form a negative pressure at the liquid inlet chamber, thereby drawing the second formulation from the second water inlet pipe into the liquid inlet chamber. The first and second formulations are rapidly and evenly mixed in the Venturi tube, and a large number of fine bubbles are generated in the mixture, which can effectively improve the reaction rate and mass transfer efficiency of the propylthiouracil formulation and effectively improve the mixing effect.

[0005] The device is equipped with a gas guide pipe and a gas outlet valve. The gas outlet valve can effectively discharge the high-pressure gas in the preparation reaction vessel. The high-pressure gas pushes the sliding piston to move upward, thereby allowing the high-pressure gas to be discharged from the gas outlet. The gas outlet valve can improve the gas pressure stability of the preparation reaction vessel, greatly improving the installation and stability of the reaction.

[0006] This utility model also provides a reaction apparatus for a propylthiouracil formulation, comprising: a formulation reaction vessel, a first formulation tank, an air pump, and a second formulation tank. The first formulation tank is equipped with a water pump, and the output end of the water pump is fixedly connected to a first water inlet pipe. One end of the first water inlet pipe is fixedly connected to a Venturi tube. The second formulation tank is fixedly connected to a second water inlet pipe. The Venturi tube is provided with an inlet, a connecting neck, and an outlet in sequence. The upper side wall of the connecting neck is provided with an inlet chamber.

[0007] The upper side wall of the preparation reaction vessel is fixedly connected to an exhaust connection pipe, the upper end of the exhaust connection pipe is fixedly connected to an exhaust valve, the outer side wall of the exhaust valve is evenly provided with several exhaust holes, the outer side wall of the exhaust connection pipe and near the upper end are fixedly connected to a gas guide pipe, the upper side wall of the gas guide pipe is fixedly connected to an exhaust pipe, and the output end of the air pump extends into the preparation reaction vessel.

[0008] According to the propylthiouracil formulation reaction device, the upper side wall of the venturi tube is provided with a connecting joint, which is connected to the second water inlet pipe.

[0009] According to the propylthiouracil formulation reaction device, a third control valve is installed in the middle of the second water inlet pipe, and a fourth control valve is installed in the middle of the output end of the air pump.

[0010] According to the propylthiouracil formulation reaction apparatus, a sliding piston is slidably connected inside the outlet valve, and a return spring is provided between the upper side wall of the sliding piston and the upper inner wall of the outlet valve.

[0011] According to the propylthiouracil formulation reaction apparatus, a liquid outlet pipe is fixedly connected to the right side wall of the formulation reaction vessel near the lower side, and a first control valve is installed in the middle of the liquid outlet pipe.

[0012] According to the aforementioned apparatus for the reaction of a propylthiouracil preparation, the Venturi tube is connected to the first water inlet pipe via a liquid inlet.

[0013] According to the propylthiouracil formulation reaction device, the venturi tube is connected to the second water inlet pipe through the liquid inlet chamber.

[0014] According to the aforementioned propylthiouracil formulation reaction apparatus, a second control valve is installed in the middle of the gas outlet connection pipe.

[0015] Additional aspects and advantages of this invention will be set forth in part in the description which follows, and in part will be obvious from the description, or may be learned by practice of the invention. Attached Figure Description

[0016] The present invention will be further described below with reference to the accompanying drawings and embodiments;

[0017] Figure 1 This is a schematic diagram of the structure of a reaction device for a propylthiouracil preparation according to the present invention;

[0018] Figure 2 This is an internal schematic diagram of a reaction apparatus for a propylthiouracil preparation according to the present invention.

[0019] Figure 3This is a schematic diagram of the inside of the Venturi tube of a propylthiouracil formulation reaction device according to the present invention;

[0020] Figure 4 This is a schematic diagram of the internal structure of the vent valve of a propylthiouracil preparation reaction device according to the present invention.

[0021] Legend:

[0022] 1. Formulation reaction vessel; 101. Liquid outlet pipe; 102. First control valve; 103. Gas outlet connection pipe; 104. Second control valve; 105. Gas outlet valve; 1051. Sliding piston; 1052. Gas outlet hole; 1053. Return spring; 2. First formulation tank; 201. First water inlet pipe; 202. Water pump; 3. Second formulation tank; 301. Second water inlet pipe; 302. Third control valve; 4. Air pump; 401. Fourth control valve; 5. Gas guide pipe; 501. Exhaust pipe; 6. Venturi tube; 601. Connecting joint; 602. Liquid inlet chamber; 603. Connecting neck; 604. Liquid inlet; 605. Liquid outlet. Detailed Implementation

[0023] This section will describe in detail the specific embodiments of the present utility model. The preferred embodiments of the present utility model are shown in the accompanying drawings. The purpose of the drawings is to supplement the textual description with graphics, so that people can intuitively and vividly understand each technical feature and the overall technical solution of the present utility model, but they should not be construed as limiting the scope of protection of the present utility model.

[0024] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model; the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance. In addition, unless otherwise explicitly specified and limited, the terms "installed," "connected," and "linked" should be interpreted broadly. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium; it can be a connection within two components. For those skilled in the art, the specific meaning of the above terms in this utility model can be understood according to the specific circumstances.

[0025] Reference Figure 1-4This utility model discloses a propylthiouracil formulation reaction apparatus, comprising: a formulation reaction vessel 1, a first formulation tank 2, an air inlet pump 4, and a second formulation tank 3. A water pump 202 is installed inside the first formulation tank 2, and a first water inlet pipe 201 is fixedly connected to the output end of the water pump 202. A venturi tube 6 is fixedly connected to one end of the first water inlet pipe 201. A second water inlet pipe 301 is fixedly connected inside the second formulation tank 3. An inlet 604, a connecting neck 603, and an outlet 605 are sequentially arranged inside the venturi tube 6. An inlet is provided on the upper side wall of the connecting neck 603. The upper side wall of the venturi tube 6 is provided with a connecting joint 601, which is connected to the second water inlet pipe 301. A third control valve 302 is installed in the middle of the second water inlet pipe 301. A fourth control valve 401 is installed in the middle of the output end of the air pump 4. A liquid outlet pipe 101 is fixedly connected to the right side wall of the preparation reaction vessel 1 near the lower side. A first control valve 102 is installed in the middle of the liquid outlet pipe 101. The venturi tube 6 is connected to the first water inlet pipe 201 through the liquid inlet port 604. The venturi tube 6 is connected to the second water inlet pipe 301 through the liquid inlet chamber 602.

[0026] A gas outlet connection pipe 103 is fixedly connected to the upper side wall of the preparation reaction vessel 1. A gas outlet valve 105 is fixedly connected to the upper end of the gas outlet connection pipe 103. A plurality of gas outlet holes 1052 are evenly arranged on the outer side wall of the gas outlet valve 105. A gas guide pipe 5 is fixedly connected to the outer side wall of the gas outlet connection pipe 103 near the upper end. An exhaust pipe 501 is fixedly connected to the upper side wall of the gas guide pipe 5. The output end of the air inlet pump 4 extends into the interior of the preparation reaction vessel 1. A third control valve 302 is installed in the middle of the second water inlet pipe 301. A fourth control valve 401 is installed in the middle of the output end of the air inlet pump 4. A second control valve 104 is installed in the middle of the gas outlet connection pipe 103.

[0027] All electrical components mentioned in this article are electrically connected to an external main controller, which can be a conventional known device such as a computer for control. All electrical components mentioned in this article are electrically connected to an external power source.

[0028] Working principle: The device is equipped with a Venturi tube 6, a first preparation tank 2, and a second preparation tank 3. The water pump 202 can introduce the first preparation in the first preparation tank 2 into the liquid inlet 604 through the first water inlet pipe 201. The first preparation flows through the connecting neck 603, which can create a negative pressure at the liquid inlet chamber 602, thereby drawing the second preparation from the second water inlet pipe 301 into the liquid inlet chamber. The first and second preparations are rapidly and evenly mixed in the Venturi tube 6, and a large number of fine bubbles are generated in the mixture, which can effectively improve the reaction rate and mass transfer efficiency of the propylthiouracil preparation and effectively improve the mixing effect. The device is equipped with a gas guide pipe and a gas outlet valve 105. The gas outlet valve 105 can effectively discharge the high-pressure gas in the preparation reaction vessel 1. The high-pressure gas pushes the sliding piston 1051 to move upward, thereby allowing the high-pressure gas to be discharged from the gas outlet 1052. The gas outlet valve 105 can improve the gas pressure stability of the preparation reaction vessel, greatly improving the safety and stability of the reaction.

[0029] The embodiments of the present utility model have been described in detail above with reference to the accompanying drawings. However, the present utility model is not limited to the above embodiments. Within the scope of knowledge possessed by those skilled in the art, various changes can be made without departing from the spirit of the present utility model.

Claims

1. A reaction apparatus for a propylthiouracil formulation, characterized in that, include: The formulation reaction vessel (1), the first formulation tank (2), the air pump (4) and the second formulation tank (3) are provided. The first formulation tank (2) is equipped with a water pump (202). The output end of the water pump (202) is fixedly connected to a first water inlet pipe (201). One end of the first water inlet pipe (201) is fixedly connected to a venturi tube (6). The second formulation tank (3) is fixedly connected to a second water inlet pipe (301). The venturi tube (6) is provided with an inlet (604), a connecting neck (603) and an outlet (605) in sequence. The upper side wall of the connecting neck (603) is provided with an inlet chamber (602). The upper side wall of the preparation reaction vessel (1) is fixedly connected to an exhaust connection pipe (103), and the upper end of the exhaust connection pipe (103) is fixedly connected to an exhaust valve (105). The outer side wall of the exhaust valve (105) is evenly provided with a plurality of exhaust holes (1052). The outer side wall of the exhaust connection pipe (103) and near the upper end is fixedly connected to a gas guide pipe (5). The upper side wall of the gas guide pipe (5) is fixedly connected to an exhaust pipe (501). The output end of the air pump (4) extends into the preparation reaction vessel (1).

2. The apparatus for reacting a propylthiouracil formulation according to claim 1, characterized in that, The upper side wall of the Venturi tube (6) is provided with a connecting joint (601), which is connected to the second water inlet pipe (301).

3. The apparatus for reacting a propylthiouracil formulation according to claim 1, characterized in that, A third control valve (302) is installed in the middle of the second water inlet pipe (301), and a fourth control valve (401) is installed in the middle of the output end of the air pump (4).

4. The apparatus for reacting a propylthiouracil formulation according to claim 1, characterized in that, A sliding piston (1051) is slidably connected inside the vent valve (105), and a return spring (1053) is provided between the upper side wall of the sliding piston (1051) and the upper inner wall of the vent valve (105).

5. The apparatus for reacting a propylthiouracil formulation according to claim 1, characterized in that, A liquid outlet pipe (101) is fixedly connected to the right side wall and near the lower side of the preparation reaction vessel (1), and a first control valve (102) is installed in the middle of the liquid outlet pipe (101).

6. The apparatus for reacting a propylthiouracil formulation according to claim 1, characterized in that, The Venturi tube (6) is connected to the first water inlet pipe (201) through the liquid inlet (604).

7. The apparatus for reacting a propylthiouracil formulation according to claim 1, characterized in that, The Venturi tube (6) is connected to the second water inlet pipe (301) through the liquid inlet chamber (602).

8. The apparatus for reacting a propylthiouracil formulation according to claim 1, characterized in that, A second control valve (104) is installed in the middle of the air outlet connection pipe (103).

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