Instant detection kit for BCRABL tumor fusion gene

Abstract

The utility model relates to the technical field of detection kits, in particular to a BCRABL tumor fusion gene instant detection kit which comprises a main kit body, a plurality of reagent tubes detachably mounted at the top of the main kit body, a base and a kit sleeve, two ends of the kit sleeve are designed to be open, and two kit tops which are bonded together are rotatably mounted at the top openings. The two extrusion blocks are installed on the two opposite inner side walls of the box sleeve in a telescopic sliding mode respectively and abut against the side wall of the main box body, the vacuum suction cups are installed at the lower bottom of the box sleeve, two screws on the box sleeve are unscrewed firstly, so that the corresponding extrusion blocks do not extrude and abut against the main box body any more, then the box sleeve is extruded downwards, and the vacuum suction cups abut against the side wall of the main box body. The reagent tubes inserted into the top of the main box body collide with the box top at the top of the box sleeve, the reagent tubes with the needed number can be conveniently and accurately taken out, the vacuum suction cups can be adsorbed and fixed to a working table face along with downward pressing of the box sleeve, the needed reagent tubes can be directly drawn out from the upper portion with one hand, and the reagent box further has the advantage of being convenient to use.

Description

Technical Field

[0001] This utility model relates to the field of detection kit technology, specifically to a BCRABL tumor fusion gene point detection kit. Background Technology

[0002] The BCR / ABL tumor fusion gene point detection kit is an important detection tool for blood diseases such as chronic myeloid leukemia (CML).

[0003] Traditional BCR / ABL tumor fusion gene point detection kits mainly consist of a box and reagent tubes placed inside the box. To use them, simply open the cover on the box and remove the required reagent tubes from the kit.

[0004] However, there are two inconveniences in the process of removing the reagent kit;

[0005] The reagent tubes in the kit are usually inserted into the kit by plugging them in. If the plugging force is too strong or due to shaking during transportation, the reagent tubes can easily become stuck. When removing them, the operator needs to use both hands, holding the kit in one hand and pulling out the reagent tube with the other, which makes it difficult to remove them from the kit and causes inconvenience.

[0006] To increase the capacity, the reagent kit usually contains multiple reagent tubes. With multiple reagent tubes placed together and the internal space of the kit being small, it is easy to take too many or too few reagent tubes, which causes inconvenience in use. Utility Model Content

[0007] In view of the above-mentioned shortcomings of the existing technology, the present invention provides a BCRABL tumor fusion gene instant detection kit, which can effectively solve the problems mentioned in the background technology.

[0008] To achieve the above objectives, this utility model provides the following technical solution:

[0009] This utility model provides a BCRABL tumor fusion gene point detection kit, including a main box and several reagent tubes detachably installed on the top of the main box, a base, a box sleeve with openings at both ends, and two box tops that are rotatably installed at the top opening and bonded together. Two extrusion blocks are respectively telescopically slidably installed on two opposite inner side walls of the box sleeve and abut against the side walls of the main box. Several vacuum suction cups are installed at the bottom of the box sleeve.

[0010] Furthermore, the top of the main box has several insertion holes, the inner walls of the insertion holes are filled with rubber liners, and the reagent tubes are respectively inserted into the corresponding rubber liners.

[0011] Furthermore, the two opposite outer walls of the main box are provided with sliding grooves, and a base plate is installed at the bottom of the main box. Several through holes are provided on the base plate to facilitate the lifting and sliding of the vacuum suction cup.

[0012] Furthermore, the box sleeve has round holes on both sides, and screws are threaded between the round holes and the inner wall of the box sleeve. The compression block is installed on one end of the screw, and a knob set in the round hole is fixedly installed on the other end of the screw.

[0013] Furthermore, sliders are fixedly installed on both opposite inner sidewalls of the box sleeve, and several sliders are slidably installed in corresponding grooves.

[0014] The technical solution provided by this utility model has the following advantages compared with the known prior art:

[0015] 1. The reagent kit is designed as a two-piece set, consisting of a main box and a sleeve that fits over the main box. When it is necessary to remove the reagent tubes from the kit, first loosen the two screws on the sleeve so that the corresponding squeezing blocks no longer press against the main box. Then, squeeze the sleeve downwards so that the reagent tubes inserted at the top of the main box break through the top of the sleeve and are directly exposed. This allows for easy and accurate removal of the required number of reagent tubes, making it convenient to use.

[0016] 2. As the box sleeve is pressed down, several vacuum suction cups will descend simultaneously until they are adsorbed and fixed on the workbench. At this time, the box sleeve and the main box body are integrated and fixed on the workbench. The required reagent tubes can be directly pulled out with one hand from above, which further enhances the ease of use. Attached Figure Description

[0017] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0018] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0019] Figure 2 This is a schematic diagram of the main box and reagent tube structure of this utility model;

[0020] Figure 3 This is a schematic diagram of the box sleeve structure of this utility model;

[0021] Figure 4 This is a schematic diagram of the extrusion block installation structure of this utility model.

[0022] The labels in the diagram represent:

[0023] 1. Main box body; 11. Insertion hole; 12. Rubber lining; 13. Slide groove; 14. Base plate; 15. Through hole;

[0024] 2. Reagent tubes;

[0025] 3. Box sleeve; 31. Round hole; 32. Knob; 33. Screw; 34. Extrusion block; 35. Slider; 36. Vacuum suction cup. Detailed Implementation

[0026] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions of the embodiments of this utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without creative effort are within the scope of protection of this utility model.

[0027] The present invention will be further described below with reference to the embodiments.

[0028] Example 1

[0029] Reference Figure 1-4 This is the first embodiment of the present invention, disclosing a BCRABL tumor fusion gene point-of-care testing kit, including a main box 1 and several reagent tubes 2 detachably mounted on the top of the main box 1. The reagent tubes 2 contain BCRABL tumor fusion gene point-of-care testing reagents for detecting the presence of the BCR / ABL fusion gene in leukemia bone marrow cells. It is primarily intended for CML patients, but can also be used for the differential diagnosis of some acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) patients. The box 3 has openings at both ends and an open top. Two box tops, which are glued together, are rotated and installed at the opening. The two box tops are rectangular cardboard pieces, and glue is applied to the edges of the two cardboard pieces on opposite sides. When the box 3 is lowered, the two box tops will be opened by several reagent tubes 2, exposing the reagent tubes 2 for easy access. Two extrusion blocks 34 are respectively telescopically slidably installed on the two opposite inner side walls of the box 3 and abut against the side wall of the main box 1. Several vacuum suction cups 36 are installed on the bottom of the box 3. The inner cavity of the box 3 is wider than the width of the main box 1, so that the extrusion blocks 34 have sufficient space to accommodate them.

[0030] Example 2

[0031] Reference Figure 1-4This is the second embodiment of the present invention. This embodiment differs from the first embodiment in that: the top of the main box 1 has several insertion holes 11, the inner walls of which are filled with rubber liners 12 to improve the anti-collision protection of the reagent tubes 2 and prevent damage to the reagent tubes 2 during transportation due to collisions with the inner walls of the insertion holes 11. Several reagent tubes 2 are respectively inserted into their corresponding rubber liners 12. Sliding grooves 13 are provided on both opposite outer walls of the main box 1. A base plate 14 is installed at the bottom of the main box 1, and several through holes 15 are provided on the base plate 14 to facilitate the lifting and sliding of the vacuum suction cup 36. The diameter of hole 15 is larger than the maximum outer diameter of vacuum suction cup 36, and vacuum suction cup 36 is positioned opposite to through hole 15. Circular holes 31 are provided on both sides of box sleeve 3. Screws 33 are threaded between circular holes 31 and the inner wall of box sleeve 3. Extrusion block 34 is installed on one end of screw 33, and a knob 32 is fixedly installed in the circular hole 31 on the other end of screw 33. Slider blocks 35 are fixedly installed on both opposite inner walls of box sleeve 3. Several sliders 35 are slidably installed in corresponding slide grooves 13. The limiting of sliders 35 and slide grooves 13 prevents box sleeve 3 from detaching from main box body 1 and improves the stability of box sleeve 3 when it is raised and lowered.

[0032] The remaining structure is the same as that in Example 1.

[0033] The workflow of this utility model is as follows:

[0034] In the unused state, the box sleeve 3 is fitted on the top of the main box 1. The two mutually bonded box tops of the top of the box sleeve 3 are laid flat on the top of the box sleeve 3, which together with the box sleeve 3 completes the impact protection of the top and surrounding area of ​​the main box 1 and several reagent tubes 2. At this time, the two squeezing blocks 34 squeeze and abut against the two sides of the main box 1 respectively, and complete the locking and fixation between the main box 1 and the box sleeve 3, thereby improving the safety protection of the box sleeve 3 for the main box 1 and several reagent tubes 2.

[0035] In use, first place the base plate 14 on the workbench, loosen the two screws 33 by turning the knob 32 so that the corresponding squeezing block 34 no longer squeezes against the main box 1. Then squeeze the box sleeve 3 downwards, and the top of the box sleeve 3, which was originally glued together, is separated from the glued relationship through the top of several reagent tubes 2, and is forced to rotate open. As the height of the box sleeve 3 decreases, it will drive the height of several vacuum suction cups 36 to decrease. Several vacuum suction cups 36 pass through the corresponding through holes 15, and finally squeeze against the workbench surface and expel the air in the vacuum suction cups 36, completing the adsorption and fixation of the vacuum suction cups 36 to the workbench. Finally, tighten the two screws 33 to complete the limiting fixation of the squeezing block 34 to the main box 1, and complete the temporary locking fixation between the box sleeve 3 and the main box 1. At this time, several reagent tubes 2 are fully exposed, making it convenient for the operator to accurately and stably pick up the designated reagent tubes 2.

[0036] The above embodiments are only used to illustrate the technical solutions of this utility model, and are not intended to limit it. Although this utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features. Such modifications or substitutions will not cause the essence of the corresponding technical solutions to deviate from the protection scope of the technical solutions of the embodiments of this utility model.

Claims

1. A BCRABL tumor fusion gene point detection kit, comprising a main housing (1) and several reagent tubes (2) detachably mounted on the top of the main housing (1), characterized in that, Also includes: The box sleeve (3) has an opening at both ends, and two box tops that are glued together are rotated and installed at the top opening; Two extrusion blocks (34) are telescopically and slidably installed on the two opposite inner sidewalls of the box sleeve (3) and abut against the sidewall of the main box body (1); Several vacuum suction cups (36) are installed on the bottom of the box sleeve (3).

2. The BCRABL tumor fusion gene point detection kit according to claim 1, characterized in that, The top of the main box (1) is provided with several insertion holes (11), and the inner walls of the several insertion holes (11) are filled with rubber liners (12). Several reagent tubes (2) are respectively inserted into the corresponding rubber liners (12).

3. The BCRABL tumor fusion gene point detection kit according to claim 1, characterized in that, The two opposite outer walls of the main box (1) are provided with sliding grooves (13), and the bottom of the main box (1) is provided with a base plate (14). The base plate (14) is provided with several through holes (15) to facilitate the lifting and sliding of the vacuum suction cup (36).

4. The BCRABL tumor fusion gene point detection kit according to claim 1, characterized in that, The box sleeve (3) has round holes (31) on both sides. Screws (33) are threaded between the round holes (31) and the inner wall of the box sleeve (3). The extrusion block (34) is installed on one end of the screw (33). A knob (32) is fixedly installed in the round hole (31) on the other end of the screw (33).

5. The BCRABL tumor fusion gene point detection kit according to claim 3, characterized in that, The two opposite inner walls of the box sleeve (3) are fixedly installed with sliders (35), and a number of the sliders (35) are slidably installed in the corresponding grooves (13).

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