Liquid detection device

Abstract

The utility model belongs to the technical field of in-vitro diagnosis, and particularly relates to a liquid detection device. The liquid detection device comprises a shell assembly, detection paper and a cover body, the shell assembly is provided with a first containing cavity, the same side of the shell assembly is provided with a liquid inlet hole and an observation hole respectively, the liquid inlet hole and the observation hole are communicated with the first containing cavity respectively, the detection paper is arranged in the first containing cavity, and the cover body is arranged in the first containing cavity. One end of the detection paper corresponds to the position of the liquid inlet hole, the other end of the detection paper corresponds to the position of the observation hole, the cover body is provided with a second containing cavity, part of the shell assembly is contained in the second containing cavity, and the cover body is detachably connected with the shell assembly and configured to be used for blocking the liquid inlet hole. According to the technical scheme provided by the utility model, the operation of collecting and detecting can be completed in one step, the operation is simple and easy to use, and meanwhile, the biological safety risk and the risk that a sample is polluted caused by contact between a detector and the sample are greatly reduced.

Description

Technical Field

[0001] This utility model belongs to the field of in vitro diagnostic technology, specifically relating to a liquid detection device. Background Technology

[0002] Currently available conventional urine testing devices first collect urine samples using a urine cup, then add a sufficient amount of urine sample to the designated sample application point on a strip-type or card-type reagent testing device. Alternatively, the sample application end of a strip-type device is inserted into the urine, and the urine sample is chromatographically deposited towards the viewing window under capillary force. In colloidal gold test strips, the coupling pad is coated with a labeled immune complex. When the sample passes through the coupling pad, the analyte in the sample undergoes an immune reaction with the immunolabeled complex and binds. The bound analyte-immunolabeled complex then chromatographically deposits onto a nitrocellulose membrane, where it is captured by antibodies coated with control and detection lines, thus forming a visible test band. However, existing urine testing methods require a urine cup and dropper, increasing product components, and necessitate steps such as sample collection, transfer, and loading, making the operation relatively complex. Utility Model Content

[0003] The purpose of this invention is to at least solve the problem of the complexity of existing urine testing procedures. This purpose is achieved through the following technical solution:

[0004] The first aspect of this utility model provides a liquid detection device, comprising:

[0005] A housing assembly having a first accommodating cavity, and a liquid inlet and an observation hole respectively provided on the same side of the housing assembly, the liquid inlet and the observation hole respectively communicating with the first accommodating cavity;

[0006] The test paper is disposed in the first accommodating cavity, with one end of the test paper corresponding to the position of the liquid inlet and the other end of the test paper corresponding to the position of the observation hole;

[0007] A cover having a second receiving cavity in which a portion of the housing assembly is received, wherein the cover is detachably connected to the housing assembly and configured to block the liquid inlet.

[0008] According to the technical solution of this utility model, the first accommodating cavity inside the housing assembly is used to contain the test paper. When the liquid detection device detects liquid, the liquid can flow through the inlet hole to one end of the test paper corresponding to the inlet hole, and permeate and flow on the test paper. The result of the tested liquid sample can be displayed on the other end of the test paper and can be seen by the user through the observation hole. In addition, the cover is detachably fitted outside the housing assembly to protect the inlet hole. The liquid detection device in this utility model can retain the liquid sample through the inlet hole, eliminating the steps of collecting the liquid with a liquid cup and then transferring the liquid sample with a dropper. It realizes the operation of collecting and detecting in one step, which is simple and easy to use. At the same time, it greatly reduces the biosafety risks caused by the tester's contact with the sample and the risk of sample contamination.

[0009] In addition, the liquid detection device according to this utility model may also have the following additional technical features:

[0010] In some embodiments of this utility model, the housing assembly includes a first housing and a second housing, the first housing and the second housing are fastened together and surround to form the first accommodating cavity, and the liquid inlet and the observation hole are both provided on the first housing.

[0011] In some embodiments of this utility model, a fixed platform is provided on the side of the second housing facing the first housing, and a barrier platform is provided on the side of the first housing facing the second housing. The barrier platform is located on the side of the liquid inlet facing the observation hole. A first channel is formed between the barrier platform and the fixed platform. The first channel is used to accommodate the test paper. One side of the test paper is fitted to the fixed platform, and there is a gap between the other side of the test paper and the barrier platform.

[0012] In some embodiments of this utility model, a first sidewall is provided on the side of the liquid inlet facing the observation hole, a first buffer space is formed between the first sidewall and the barrier platform, and the first buffer space is connected to the first channel.

[0013] In some embodiments of this utility model, the fixing platform includes a support portion, a first limiting portion, and a second limiting portion. The support portion is arranged along the length direction of the second housing. The first limiting portion and the second limiting portion are arranged on both sides of the support portion along the width direction of the second housing. There is a snap-fit ​​space between the first limiting portion and the second limiting portion. The blocking platform can snap into the snap-fit ​​space. The detection paper is located between the first limiting portion and the second limiting portion and is disposed between the support portion and the blocking platform.

[0014] In some embodiments of this utility model, the size of the support portion increases in the direction from the liquid inlet to the observation hole and in the arrangement direction from the first housing to the second housing.

[0015] In some embodiments of this utility model, multiple blocking platforms are provided, multiple first limiting parts are provided, multiple second limiting parts are provided, the first limiting parts and the second limiting parts correspond one-to-one, each first limiting part and the corresponding second limiting part have a locking space, and each blocking platform can lock and cooperate with a locking space.

[0016] In some embodiments of this utility model, a second buffer space is formed between adjacent barrier platforms, and the second buffer space is connected to the first channel.

[0017] In some embodiments of this utility model, the fixed platform further includes a third limiting part, a fourth limiting part, and a fifth limiting part. The two ends of the third limiting part along the width direction of the second housing are respectively connected to the fourth limiting part and the fifth limiting part. The third limiting part, the fourth limiting part, and the fifth limiting part enclose a limiting space. The limiting space has an opening structure. The end of the support part away from the liquid inlet extends into the limiting space through the opening structure. The end of the detection paper away from the liquid inlet abuts against the third limiting part, the fourth limiting part, and the fifth limiting part.

[0018] In some embodiments of this utility model, one of the first housing and the second housing is provided with a positioning boss, and the other of the first housing and the second housing is provided with a positioning groove, wherein the positioning boss and the positioning groove are inserted into each other.

[0019] In some embodiments of this utility model, the liquid detection device further includes a transparent element, which is attached to the observation hole.

[0020] In some embodiments of this utility model, the liquid inlet hole includes multiple partitions and multiple holes. The partitions are spaced apart along the length direction of the housing assembly to divide the liquid inlet hole into multiple holes. The number of holes is a, and the number of partitions is b, where a = b + 1.

[0021] In some embodiments of this utility model, the detection paper is colloidal gold test paper, dry chemical test paper, or fluorescent test paper. Attached Figure Description

[0022] Various other advantages and benefits will become apparent to those skilled in the art upon reading the following detailed description of preferred embodiments. The accompanying drawings are for illustrative purposes only and are not intended to limit the scope of the invention. Furthermore, the same reference numerals denote the same parts throughout the drawings. In the drawings:

[0023] Figure 1 A schematic diagram of the structure of a liquid detection device according to an embodiment of the present invention is shown.

[0024] Figure 2 for Figure 1 Explosion-proof schematic diagram of a liquid detection device;

[0025] Figure 3 for Figure 1 A schematic diagram of the structure of the cover of the liquid detection device;

[0026] Figure 4 for Figure 3 A cross-sectional structural diagram of the cover of the liquid detection device;

[0027] Figure 5 for Figure 1 A schematic diagram of the structure of the first housing of the housing assembly of the liquid detection device;

[0028] Figure 6 for Figure 5 A structural schematic diagram of the first housing assembly of the liquid detection device from another perspective;

[0029] Figure 7 for Figure 1 A schematic diagram of the structure of the second housing of the housing assembly of the liquid detection device;

[0030] Figure 8 for Figure 7 A schematic diagram of the second housing of the housing assembly of the liquid detection device from another perspective;

[0031] Figure 9 for Figure 1 Schematic diagram of the assembly structure of the second housing and detection paper of the liquid detection device;

[0032] Figure 10 for Figure 1 A schematic diagram of the colloidal gold / fluorescent detection paper in a liquid detection device;

[0033] Figure 11 for Figure 1 A schematic diagram of the dry chemical detection paper in a liquid detection device;

[0034] Figure 12 for Figure 1A cross-sectional structural diagram of a liquid detection device;

[0035] Figure 13 for Figure 1 A cross-sectional structural diagram of the liquid detection device in its first operating state;

[0036] Figure 14 for Figure 2 Enlarged schematic diagram of part of the structure of the liquid level detection device;

[0037] Figure 15 for Figure 1 A cross-sectional structural diagram of the liquid detection device in its second state during operation.

[0038] The labels in the attached diagram are as follows:

[0039] 11. First shell; 111. Observation hole; 1111. Planar runway; 112. Liquid inlet; 1121. Divider; 1122. Hole; 1123. First sidewall; 113. Protrusion; 1141. First barrier platform; 1142. Second barrier platform; 1143. First buffer space; 1144. Second buffer space; 1151. First abutment platform; 1152. Second abutment platform; 116. Spiked structure; 117. Positioning boss; 118. First channel; 12. Second shell; 121. Fixing platform; 1211. Support; 1212. First limiting part; 1213. Second limiting part; 1214. First locking space; 1215. Second locking space; 1216. Third limiting part; 1217. Fourth limiting part; 1218. Fifth limiting part; 1219. Limiting space;

[0040] 20. Test paper; 21. First PVC backing layer; 22. Test sample layer; 23. Coupler layer; 24. Nitrocellulose layer; 25. Absorbent layer; 26. Second PVC backing layer; 27. Dry chemical sample layer; 28. Dry chemical reaction layer; 291. Overlapping area between test sample layer and coupler layer; 292. Overlapping area between coupler layer and nitrocellulose layer;

[0041] 30. Cover; 31. Concave point;

[0042] 40. Transparent parts. Detailed Implementation

[0043] Exemplary embodiments of the present disclosure will now be described in more detail with reference to the accompanying drawings. While exemplary embodiments of the present disclosure are shown in the drawings, it should be understood that the present disclosure may be implemented in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete, and will fully convey the scope of the disclosure to those skilled in the art.

[0044] It should be understood that the terminology used herein is for the purpose of describing particular exemplary embodiments only and is not intended to be limiting. Unless the context clearly indicates otherwise, the singular forms “a,” “an,” and “described” as used herein may also include the plural forms. The terms “comprising,” “including,” “containing,” and “having” are inclusive and therefore indicate the presence of the stated features, steps, operations, elements, and / or components, but do not exclude the presence or addition of one or more other features, steps, operations, elements, components, and / or combinations thereof. The method steps, processes, and operations described herein are not construed as requiring them to be performed in a particular order described or illustrated unless the order of performance is explicitly indicated. It should also be understood that additional or alternative steps may be used.

[0045] Although terms such as first, second, third, etc., may be used in this document to describe multiple elements, components, regions, layers, and / or segments, these elements, components, regions, layers, and / or segments should not be limited by these terms. These terms may be used only to distinguish one element, component, region, layer, or segment from another. Unless the context clearly indicates otherwise, terms such as "first," "second," and other numerical terms used herein do not imply order or sequence. Therefore, the first element, component, region, layer, or segment discussed below may be referred to as the second element, component, region, layer, or segment without departing from the teachings of the exemplary embodiments.

[0046] For ease of description, spatial relative terms may be used in the text to describe the relationship of one element or feature relative to another element or feature, as shown in the figure. These relative terms include, for example, "inside," "outside," "middle," "outer," "below," "below," "above," "over," etc. Such spatial relative terms are intended to include different orientations of the device in use or operation, other than those depicted in the figure. For example, if the device in the figure is flipped, an element described as "below other elements or features" or "below other elements or features" would subsequently be oriented "above other elements or features" or "above other elements or features." Therefore, the example term "below" can include both upper and lower orientations.

[0047] Currently, in vitro diagnostic products, represented by colloidal gold technology and dry chemistry technology, have been widely used due to their advantages such as ease of operation, low cost, and short reaction time, especially in the field of home self-testing, where they have a large market prospect. As an important branch of in vitro diagnostics, colloidal gold technology emerged and rapidly spread in the 1990s. Its characteristic is the use of antigen-antibody immunological reactions to detect analytes. This detection technology is based on the principle of chromatography and can detect whether the sample contains the specific antigen or antibody to be detected. Immunochromatography can quickly and conveniently provide reliable test results for samples.

[0048] Dry chemistry is a modern medical testing method that involves pre-fixing the reagents required for the reaction onto a specially structured carrier. The sample to be tested reacts chemically with the reagents on the carrier, generating a chemical signal, which is then detected visually or by instruments. This technology is suitable for use in primary healthcare institutions and on-site, and is typically available in the form of dry strip test papers to achieve rapid and accurate detection of analytes.

[0049] Urine contains numerous substances that reflect the body's state, making it a frequent target for in vitro diagnostics, particularly colloidal gold and dry chemistry techniques. These techniques often provide diagnostic support to doctors and patients. There are two common methods for urine sample testing: one involves collecting the sample in a urine cup, then using a dropper to apply it to a chromatographic test strip for reaction, and waiting for the results to be read; the other involves collecting the sample in a urine cup, inserting the sample pad end of the test strip into the cup, and then chromatographically transferring the urine sample onto the strip for testing. As you can see, both common methods require collecting the urine sample in a urine cup before testing. During urine collection and testing, the prolonged exposure of the sample and the sample transfer process pose certain biosafety risks. If the sample contains pathogens or viruses, it can easily cause secondary contamination to the testing personnel. Furthermore, the collection and testing procedures are relatively complex and not user-friendly for non-professionals, requiring a learning curve. Improper operation can easily affect the accuracy of the results.

[0050] To meet the growing demand in the in vitro diagnostics market, especially the home testing market, there is a need for an integrated urine sample collection and testing device to address the current problems encountered in the rapid testing of urine samples. At the same time, it is necessary to provide a more convenient, efficient, safe, and stable testing device that is compatible with colloidal gold and dry chemical test strips.

[0051] Taking a conventional urine testing device currently on the market as an example, firstly, a urine sample is collected using a urine cup. Then, a sufficient amount of urine sample is added to the designated sample application position on the strip-type urine testing device or card-type reagent, or the sample application end of the strip-type urine testing device is inserted into the urine, and the urine sample is chromatographically deposited towards the viewing window under capillary force. In the test strip of colloidal gold products, the coupling pad is coated with a labeled immune complex. When the sample passes through the coupling pad, the target analyte in the sample undergoes an immune reaction with the immunolabeled complex and binds. The bound analyte-immunolabeled complex chromatographically deposited on the nitrocellulose membrane is captured by the antibodies coated on the control line and detection line, thus forming a visible detection band.

[0052] However, the above procedures require urine cups and droppers, increasing the product composition; they also involve steps such as sample collection, transfer, and loading, making the operation relatively complex; the human error between each step is significant, posing a considerable learning cost for untrained personnel and increasing the risk of operational errors, which can adversely affect experimental results and reduce the accuracy and reliability of the product. Furthermore, prolonged exposure of samples to air during the testing process may lead to unpredictable biosafety risks and sample contamination.

[0053] In addition, some new liquid detection devices have eliminated the use of urine cups, instead using absorbent pads or washable cotton to directly receive liquid samples. The key feature is that urine can be directly poured onto the absorbent cotton for sample loading. To ensure sufficient sample for the detection reaction, a color-changing block indicating sample quantity is usually attached to the absorbent cotton, addressing the issue of incomplete chromatography due to insufficient sample volume. The urine sample in the absorbent cotton is chromatographically deposited towards the viewing window under capillary action. In colloidal gold test strips, the coupling pad is coated with a labeled immune complex. When the sample passes through the coupling pad, the analyte in the sample binds to the immunolabeled complex after an immune reaction. The bound analyte-immunolabeled complex then chromatographically deposited onto a nitrocellulose membrane, where it is captured by antibodies coated with control and detection lines, thus forming a visible detection band.

[0054] However, while the above operation eliminates the urine cup and dropper components, enabling direct sample loading and detection in one step, it requires the addition of absorbent cotton and color-changing blocks to ensure sufficient sample volume. This increases product complexity and fails to address the issue of sample overload. The urine-washing operation makes sample volume difficult to control. Due to the high kinetic energy of the sample, urine can easily flow directly from the sample loading end into the reaction zone, or even directly into the viewing window. The sample may not make sufficient contact with the sample pad and coupling pad on the test strip, significantly impacting performance and potentially leading to erroneous results.

[0055] Figure 1A schematic diagram of the structure of a liquid detection device according to an embodiment of the present invention is shown. Figure 2 for Figure 1 A schematic diagram of the exploded structure of a liquid detection device. Figure 1 and 2 As shown, this utility model proposes a liquid detection device. The liquid detection device of this utility model includes a housing assembly, a detection paper 20, and a cover 30. The housing assembly has a first receiving cavity. An inlet hole 112 and an observation hole 111 are respectively provided on the same side of the housing assembly, and the inlet hole 112 and the observation hole 111 are respectively connected to the first receiving cavity. The detection paper 20 is disposed in the first receiving cavity, with one end of the detection paper 20 corresponding to the position of the inlet hole 112 and the other end of the detection paper 20 corresponding to the position of the observation hole 111. The cover 30 has a second receiving cavity, and a portion of the housing assembly is housed in the second receiving cavity. The cover 30 is detachably connected to the housing assembly and is configured to block the inlet hole 112.

[0056] According to the technical solution of this utility model, the first accommodating cavity inside the housing assembly is used to accommodate the test paper 20. When the liquid detection device detects liquid, the liquid can flow through the liquid inlet 112 to one end of the test paper 20 corresponding to the liquid inlet 112, and permeate and flow on the test paper 20. The result of the detected liquid sample can be displayed at the other end of the test paper 20 and can be seen by the user through the observation hole 111. In addition, the cover 30 is detachably sleeved on the outside of the housing assembly to protect the liquid inlet 112. The liquid detection device in this utility model can intercept the liquid sample through the liquid inlet 112, eliminating the steps of collecting liquid with a liquid cup and then transferring the liquid sample with a dropper. It realizes the operation of collecting and detecting in one step, which is simple and easy to use. At the same time, it greatly reduces the biosafety risk and sample contamination risk caused by the tester contacting the sample.

[0057] Specifically, in this embodiment, the liquid sample can be urine. For example... Figure 10 As shown, the test paper 20 can be colloidal gold / fluorescent test paper, which is composed of a sample layer 22, a coupling agent layer 23, a nitrocellulose layer 24, an absorbent layer 25, and a first PVC base layer 21. The sample layer 22, the coupling agent layer 23, the nitrocellulose layer 24, and the absorbent layer 25 are all disposed on the same side of the first PVC base layer 21, and the sample layer 22, the coupling agent layer 23, the nitrocellulose layer 24, and the absorbent layer 25 are connected sequentially. The sample layer 22 is correspondingly disposed with the liquid inlet hole 112, and the nitrocellulose layer 24 is correspondingly disposed with the observation hole 111.

[0058] Specifically, in this embodiment, such as Figure 6 As shown, the first housing 11 has a spike structure 116 on the side facing the second housing 12 to fix the absorbent layer 25 of the test paper 20.

[0059] Specifically, in this embodiment, the test paper 20 is the core component for detecting the analyte. The normal operation of the test paper 20 requires a certain amount of sample. Too much or too little sample will affect the accuracy of the results.

[0060] In some embodiments of this utility model, such as Figure 1 and 2 As shown, the housing assembly includes a first housing 11 and a second housing 12, which are fastened together to form a first receiving cavity. An inlet hole 112 and an observation hole 111 are both located on the first housing 11. In this embodiment, the first housing 11 and the second housing 12 are detachably fastened together, facilitating the assembly and disassembly of the housing assembly, improving disassembly and assembly efficiency, and making it easier to place the test paper 20 into or remove it from the first receiving cavity.

[0061] Specifically, in this embodiment, the first housing 11 facing the second housing 12 and the second housing 12 facing the first housing 11 are both provided with receiving grooves. When the first housing and the second housing are fastened together, the two receiving grooves define the first receiving cavity.

[0062] Specifically, in this embodiment, such as Figure 1 and 2 As shown, the inlet hole 112 and the observation hole 111 are provided on the first housing 11, which makes it convenient for the operator to introduce urine into the inlet hole 112 from one direction of the housing assembly and observe the test results through the observation hole 111. If the observation hole 111 and the inlet hole 112 are provided on opposite sides of the housing assembly, urine may flow out through the inlet hole 112 while the test results are being observed, which will cause inconvenience to the observation.

[0063] In some embodiments of this utility model, such as Figure 6 and 7 As shown, a fixed platform 121 is provided on the side of the second housing 12 facing the first housing 11, and a barrier platform is provided on the side of the first housing 11 facing the second housing 12. The barrier platform is located on the side of the liquid inlet 112 facing the observation hole 111. A first channel 118 is formed between the barrier platform and the fixed platform 121. The first channel 118 is used to accommodate the test paper 20. One side of the test paper 20 is fitted to the fixed platform 121, and there is a gap between the other side of the test paper 20 and the barrier platform. Specifically, in this embodiment, there is a gap between the barrier platform and the test paper 20, which can ensure normal and slow liquid chromatography while intercepting excessive liquid, preventing the sample from directly rushing to the observation hole 111 due to excessive kinetic energy when urinating. In some embodiments of this utility model, such as Figure 7As shown, the fixed platform 121 includes a support portion 1211, a first limiting portion 1212, and a second limiting portion 1213. The support portion 1211 is arranged along the length direction of the second housing 12. The first limiting portion 1212 and the second limiting portion 1213 are arranged on both sides of the support portion 1211 along the width direction of the second housing 12. There is a snap-fit ​​space between the first limiting portion 1212 and the second limiting portion 1213. The blocking platform can snap into the snap-fit ​​space. The detection paper 20 is located between the first limiting portion 1212 and the second limiting portion 1213 and abuts against the support portion 1211 and the blocking platform. In this embodiment, the support portion 1211 is used to support and place the test paper 20. The first limiting portion 1212 and the second limiting portion 1213 are located on both sides of the support portion 1211 along the width direction of the second housing 12. They can limit and position the test paper 20 on both sides of the support portion 1211, ensuring the accuracy of the position of the test paper 20 on the support portion 1211. They can also prevent the test paper 20 from shifting after contacting urine, thus improving reliability.

[0064] In some embodiments of this utility model, such as Figure 7 As shown, along the direction from the liquid inlet 112 to the observation hole 111, the length of the support portion 1211 increases in a first direction, which is parallel to the arrangement direction of the first housing 11 and the second housing 12. In this embodiment, the above arrangement ensures that the detection paper 20 on the support portion 1211 is inclined, with one end of the detection paper 20 corresponding to the liquid inlet 112 at the lower end and the other end of the detection paper 20 corresponding to the observation hole 111 at the higher end. This inclined state allows the detection paper 20 to retain excess liquid sample at the front end of the detection paper 20 pad after chromatography, preventing excessive sample volume from adversely affecting the detection results.

[0065] Specifically, in this embodiment, the barrier stage engages with the engagement space and abuts against the test paper 20 on the support 1211. This not only limits the position of the test paper 20 but also prevents a large amount of urine from flowing from the lower end of the engagement space into the upper end of the test paper 20, thereby affecting the test results. In this embodiment, the barrier stage acts as a gate, retaining excess liquid sample at the front end of the test paper 20 to prevent excessive sample volume from adversely affecting the test results.

[0066] In some embodiments of this utility model, multiple barrier stages are provided, multiple first limiting parts 1212 are provided, and multiple second limiting parts 1213 are provided. The first limiting parts 1212 and the second limiting parts 1213 correspond one-to-one. Each first limiting part 1212 and the corresponding second limiting part 1213 have a locking space, and each barrier stage can engage with a locking space. In this embodiment, the one-to-one combination structure of multiple barrier stages and multiple locking spaces can not only further fix the test paper 20 on the support part 1211, but also serve as multiple gates to retain excess liquid sample at the front end of the test paper 20 and prevent excessive urine from flowing to the high end of the test paper 20, further preventing excessive sample volume from adversely affecting the test results.

[0067] Specifically, in this embodiment, such as Figure 6 , 7 As shown in Figure 9, four barrier platforms are provided on the side of the first housing 11 facing the second housing 12, namely the first barrier platform 1141 and the second barrier platform 1142. Two locking spaces are provided, namely the first locking space 1214 and the second locking space 1215. The first barrier platform 1141 and the second barrier platform 1142 cooperate with the first locking space 1214 and the second locking space 1215 of the second housing 12 to form two gates, which can prevent excessive liquid from flowing from the surface of the detection paper 20 to the coupling layer 23 or even to the nitrocellulose layer 24 and affecting the detection results.

[0068] In some embodiments of this utility model, a first sidewall 1123 is provided on the side of the liquid inlet 112 facing the observation hole 111, and a first buffer space 1143 is formed between the first sidewall 1123 and the first barrier platform 1141, the first buffer space 1143 being connected to the first channel 118. In this embodiment, as... Figure 13 and 14 As shown, the arrow indicates the direction of liquid flow. The first barrier stage 1141 will block most of the liquid sample in the first buffer space 1143. At this time, part of the liquid sample flows through the gap between the first barrier stage 1141 and the detection sample layer 22, and the other part is directly absorbed by the detection sample layer 22 from its internal capillary action and rises.

[0069] In this embodiment, a second buffer space 1144 is formed between adjacent barrier platforms, and the second buffer space 1144 is connected to the first channel 118. For example... Figure 13 and 15As shown, the arrows indicate the direction of liquid flow. The second barrier stage 1142 will block the remaining liquid sample within the second buffer chamber. At this time, part of the liquid sample flows through the gap between the second barrier stage 1142 and the detection sample layer 22, while the other part is directly absorbed by the detection sample layer 22 through capillary action and rises. Specifically, in this embodiment, as... Figure 6 As shown, the first housing 11 is also provided with a first abutment platform 1151 and a second abutment platform 1152 on the side facing the second housing 12. The first abutment platform 1151 and the second abutment platform 1152 gently press the connection between the sample layer 22 and the coupling material layer 23 and the connection between the coupling material layer 23 and the nitrocellulose layer 24, respectively, to ensure that the liquid flows smoothly forward for chromatography.

[0070] In some embodiments of this utility model, such as Figure 7 As shown, the fixed platform 121 also includes a third limiting part 1216, a fourth limiting part 1217, and a fifth limiting part 1218. The two ends of the third limiting part 1216 along the width direction of the second housing 12 are connected to the fourth limiting part 1217 and the fifth limiting part 1218 respectively. The third limiting part 1216, the fourth limiting part 1217, and the fifth limiting part 1218 enclose a limiting space 1219. The limiting space 1219 has an opening structure. One end of the support part 1211 away from the liquid inlet hole 112 extends into the limiting space 1219 through the opening structure. One end of the detection paper 20 away from the liquid inlet hole 112 abuts against the third limiting part 1216, the fourth limiting part 1217, and the fifth limiting part 1218 respectively. In this embodiment, the third limiting part 1216, the fourth limiting part 1217, and the fifth limiting part 1218 can enclose and form a limiting space 1219. The other end of the test paper 20 can enter the limiting space 1219 through the opening structure and be located on the support part 1211. The test paper 20 located in the limiting space 1219 can abut against the third limiting part 1216, the fourth limiting part 1217, and the fifth limiting part 1218 respectively, ensuring the limiting and fixing of the other end of the test paper 20, and further improving the positioning and fixing of the test paper 20 in the first accommodating cavity.

[0071] In some embodiments of this utility model, such as Figure 6 and 7As shown, one of the first housing 11 and the second housing 12 is provided with a positioning boss 117, and the other of the first housing 11 and the second housing 12 is provided with a positioning groove. The positioning boss 117 and the positioning groove are interlocked. In this embodiment, the periphery of the first housing 11 facing the second housing 12 is provided with multiple positioning bosses 117, and the periphery of the second housing 12 facing the first housing 11 is provided with multiple positioning grooves. Each positioning groove and a positioning boss 117 are interlocked, thereby realizing the fixing and fastening of the first housing 11 and the second housing 12. To meet the user's usage requirements, after the first and second housings are fastened, the gap between them should be uniform and ≤0.2mm; in addition, when the cover 30 is not installed, after the first and second housings are fastened, the gap between them should be ≤0.5mm when they are dropped freely from a height of 1-1.3m.

[0072] In some embodiments, applying a suitable amount of adhesive to the positioning groove or the boss 117 before fastening the first housing 11 and the second housing 12 significantly enhances the bonding strength between the upper and lower housings. The types of adhesive include, but are not limited to, silicone, acrylic, epoxy resin, and rubber. Curing methods after adhesive application include, but are not limited to, heating, ultraviolet irradiation, pressurization, humidification, and vibration. Methods for fixing the upper and lower housings also include, but are not limited to, ultrasonic welding. After the first housing 11 and the second housing 12 are fastened together, high-frequency vibration is applied to the outer surface of the contact surface between the first housing 11 and the second housing 12. The acoustic energy is transmitted to the contact surface of the two housings through the welding head, generating heat through friction between the materials. This causes the materials at the tightly contacted parts to locally melt or soften, and under a certain pressure, the melted materials solidify, forming a strong connection. ② Laser welding. After the first housing 11 and the second housing 12 are fastened together, a high-power-density laser beam is applied to the outer surface of the contact surface between the first housing 11 and the second housing 12, and the laser beam is focused on the area. The high power density of the laser beam can make the heated material melt and mix rapidly, and then solidify again during the cooling process to complete a firm connection.

[0073] In some embodiments of this utility model, such as Figure 1 and 2 As shown, the liquid detection device also includes a transparent component 40, which can be a transparent sticker or glass. The transparent sticker is affixed to the observation hole 111. In this embodiment, the transparent sticker prevents dust and other impurities from entering the first receiving cavity through the observation hole 111 and thus reaching the detection paper 20, thereby improving the detection accuracy of the detection paper 20. It also facilitates the interpretation of results by preventing liquid from splashing into the observation hole 111 during urine application. The transparent sticker is made of transparent plastic film material, with one side being adhesive, and is affixed to the observation hole 111.

[0074] Specifically, in this embodiment, the observation hole 111 has a suitable opening width for easy result interpretation, and a ring of flat tracks 1111 surrounds the observation hole 111 for attaching a transparent sticker. Considering the tester's ease of observation of the test results, the adhesive layer on the back of the transparent sticker should avoid the result display area, as the adhesive layer may obstruct the tester's view. The type of adhesive includes, but is not limited to: silicone, acrylic, epoxy resin, rubber, etc. The curing methods after applying the adhesive include, but are not limited to: heating, ultraviolet irradiation, pressurization, humidification, vibration, etc. In some embodiments, the connection between the transparent sticker and the observation hole 111 also includes: interference fit. The transparent sticker is directly embedded into the groove of the observation hole.

[0075] In some embodiments of this utility model, such as Figure 1 As shown, in some embodiments of this utility model, the liquid inlet 112 includes multiple partitions 1121 and multiple orifices 1122. The partitions 1121 are spaced apart along the length of the housing assembly to divide the liquid inlet 112 into multiple orifices 1122. The number of orifices 1122 is 'a', and the number of partitions 1121 is 'b', where a = b + 1. In this embodiment, three partitions 1121 can divide the liquid inlet 112 into four orifices 1122. Each orifice 1122 has a certain space, capable of holding a suitable volume of urine sample and retaining a sufficient amount of liquid sample to ensure the normal progress of the chromatography reaction. Multiple orifices 112 allow the liquid sample to pass through more quickly and reach the detection quantity, improving the rapid throughput of the liquid sample. After quantification, the sample is captured and fixed within the four orifices 1122, preventing excess sample from overflowing and improving reliability.

[0076] Specifically, the liquid inlet 112 is designed with a grid (three partitions 1121 divide the liquid inlet 112 into four holes 1122, which quickly intercepts a sufficient amount of liquid sample. The housing assembly is equipped with two gates (i.e., the first barrier stage 1141 and the second barrier stage 1142). The gates and the surface of the test paper 20 are left with a certain gap, which can ensure that the liquid can be slowly and normally chromatographically separated while intercepting excessive liquid, preventing the sample from rushing directly to the observation hole 111 at the back due to excessive kinetic energy when urinating). This ensures that a sufficient amount of sample is available to complete the chromatographic reaction, while also avoiding the adverse effects caused by excessive sample. This improves the ease of use of the product and also improves the stability and reliability of the test reagent.

[0077] Specifically, in this embodiment, the sample liquid during the loading process is the result of the combined action of the liquid inlet 112, multiple barrier stages, and multiple contact stages, which enables precise fluid control of the liquid and improves reliability and accuracy.

[0078] Specifically, such as Figure 11As shown, in other embodiments of this utility model, the test paper 20 can also be a dry chemical test paper, which is composed of a dry chemical sample layer 27, a dry chemical reaction layer 28, and a second PVC base layer 26. The dry chemical sample layer 27 and the dry chemical reaction layer 28 are located on the same side of the second PVC base layer 26 and are connected. The dry chemical sample layer 27 is correspondingly arranged with the liquid inlet hole 112, and the dry chemical reaction layer 28 is correspondingly arranged with the observation hole 111.

[0079] Specifically, in this embodiment, the liquid detection device is compatible with colloidal gold test strips or dry chemical test strips, and can be adapted to more application scenarios.

[0080] Specifically, in this embodiment, such as Figure 12 As shown, the overlap area 291 between the sample layer and the coupling agent layer, and the overlap area 292 between the coupling agent layer and the nitrocellulose layer, ensure close contact between the three key areas of the test strip, ensuring that the sample passes through each area in sequence and reacts fully.

[0081] Furthermore, in this embodiment, such as Figure 3 , 4 As shown in Figures 5 and 8, a recess 31 is provided on the inner side of the opening of the cover 30, and a protrusion 113 is provided on the outer side of the shell assembly, so that the cover 30 and the shell assembly are locked together by the engagement of the protrusion 113 and the recess 31. Multiple recesses 31 and protrusions 113 are provided, with each recess 31 engaging with one protrusion 113. Furthermore, the liquid detection device of this invention eliminates the need for urine cups and droppers, as well as absorbent cotton and indicators, allowing non-professionals to complete the test with simple operation. During use, urine is simply poured onto the inlet 112 of the device for a few seconds to complete the collection and testing of the urine sample, avoiding the complex operations and associated risks of sample contamination and biosafety during sample collection, transfer, and addition. The simple structural design ensures sufficient sample volume for the chromatographic reaction while avoiding adverse effects caused by excessive sample volume, improving the ease of use of the product and the stability and reliability of the detection reagents. In addition, existing devices are often only applicable to colloidal gold test strips or dry chemical test strips, while the liquid detection device of this invention can hold both colloidal gold test strips and dry chemical test strips, thus realizing multiple uses of one device.

[0082] Furthermore, the production process of the colloidal gold / fluorescent test paper or dry chemical test paper in this utility model is as follows: The colloidal gold / fluorescent test paper or dry chemical test paper is placed in the first accommodating cavity, and the test paper 20 is placed within the first snap-fit ​​space 1214, the second snap-fit ​​space 1215, and the limiting space 1219, so that the support part 1211 is fixed to the support part 1211. Then, the positioning protrusion 117 of the first housing 11 is aligned with the positioning groove of the second housing 12, and the first housing 11 and the second housing 12 are pressed together tightly. Then, the cover 30 is fitted onto the front end of the housing assembly, so that the concave point 31 on the cover 30 and the protrusion 113 of the housing assembly are locked together. Then, the adhesive side of the transparent sticker is attached to the flat track 1111 of the observation hole 111. Furthermore, the detection process of the colloidal gold / fluorescent test paper or dry chemical test paper in this utility model is as follows: remove the cover 30, hold the end of the detection device, make one end of the liquid inlet hole 112 vertically downward, and pour urine into the liquid inlet hole 112 for 3-5 seconds. Close the cover 30, place the liquid detection device horizontally on a plane and start timing. After standing for the set time, read the detection result through the observation hole 111 to complete the detection.

[0083] Compared to traditional urine testing devices, the liquid detection device in this invention has fewer components and fewer operating steps, resulting in higher efficiency, greater ease of use, more controllable sample volume, and higher success rate and reliability of test results. The safety and convenience of the product are greatly improved. This device is particularly suitable for home self-testing in everyday environments, providing safer and more reliable test results.

[0084] In addition, the liquid detection device has a highly compatible structural design. It can be fitted with colloidal gold test strips for the detection of HCG (human chorionic gonadotropin) and LH (luteinizing hormone), or with dry chemical test strips for the detection of urine pH (acidity and alkalinity) and uric acid. This high compatibility greatly expands its application scenarios.

[0085] The above description is merely a preferred embodiment of this utility model, but the protection scope of this utility model is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this utility model should be included within the protection scope of this utility model. Therefore, the protection scope of this utility model should be determined by the scope of the claims.

Claims

1. A liquid detection device, characterized in that, include: A housing assembly having a first accommodating cavity, and a liquid inlet and an observation hole respectively provided on the same side of the housing assembly, the liquid inlet and the observation hole respectively communicating with the first accommodating cavity; The test paper is disposed in the first accommodating cavity, with one end of the test paper corresponding to the position of the liquid inlet and the other end of the test paper corresponding to the position of the observation hole; A cover having a second receiving cavity, a portion of the housing assembly being received within the second receiving cavity, wherein the cover is detachably connected to the housing assembly and configured to block the liquid inlet.

2. The liquid detection device according to claim 1, characterized in that, The housing assembly includes a first housing and a second housing, which are fastened together and enclose to form the first accommodating cavity. The liquid inlet and the observation hole are both located on the first housing.

3. The liquid detection device according to claim 2, characterized in that, The second housing has a fixed platform on the side facing the first housing, and the first housing has a barrier platform on the side facing the second housing. The barrier platform is located on the side of the liquid inlet facing the observation hole. A first channel is formed between the barrier platform and the fixed platform. The first channel is used to accommodate the test paper. One side of the test paper is attached to the fixed platform, and there is a gap between the other side of the test paper and the barrier platform.

4. The liquid detection device according to claim 3, characterized in that, A first sidewall is provided on the side of the liquid inlet facing the observation hole, and a first buffer space is formed between the first sidewall and the barrier platform. The first buffer space is connected to the first channel.

5. The liquid detection device according to claim 3, characterized in that, The fixing platform includes a support portion, a first limiting portion, and a second limiting portion. The support portion is arranged along the length direction of the second housing. The first limiting portion and the second limiting portion are arranged on both sides of the support portion along the width direction of the second housing. There is a snap-fit ​​space between the first limiting portion and the second limiting portion. The blocking platform can snap into the snap-fit ​​space. The detection paper is located between the first limiting portion and the second limiting portion and is disposed between the support portion and the blocking platform.

6. The liquid detection device according to claim 5, characterized in that, The size of the support increases along the direction from the liquid inlet to the observation hole and along the arrangement direction from the first housing to the second housing.

7. The liquid detection device according to claim 5, characterized in that, The barrier platform is provided in multiple ways, the first limiting part is provided in multiple ways, and the second limiting part is provided in multiple ways. The first limiting part and the second limiting part correspond one-to-one. There is a snap-fit ​​space between each first limiting part and the corresponding second limiting part. Each barrier platform can snap-fit ​​with a snap-fit ​​space.

8. The liquid detection device according to claim 7, characterized in that, A second buffer space is formed between adjacent barrier platforms, and the second buffer space is connected to the first channel.

9. The liquid detection device according to claim 5, characterized in that, The fixed platform further includes a third limiting part, a fourth limiting part, and a fifth limiting part. The two ends of the third limiting part along the width direction of the second housing are respectively connected to the fourth limiting part and the fifth limiting part. The third limiting part, the fourth limiting part, and the fifth limiting part enclose a limiting space. The limiting space has an opening structure. The end of the support part away from the liquid inlet extends into the limiting space through the opening structure. The end of the detection paper away from the liquid inlet abuts against the third limiting part, the fourth limiting part, and the fifth limiting part.

10. The liquid detection device according to claim 2, characterized in that, One of the first housing and the second housing is provided with a positioning boss, and the other of the first housing and the second housing is provided with a positioning groove, wherein the positioning boss and the positioning groove are inserted into each other.

11. The liquid detection device according to any one of claims 1-10, characterized in that, The liquid detection device also includes a transparent component, which is attached to the observation hole.

12. The liquid detection device according to any one of claims 1-10, characterized in that, The liquid inlet includes multiple partitions and multiple holes. The partitions are spaced apart along the length of the housing assembly to divide the liquid inlet into multiple holes. The number of holes is a, and the number of partitions is b, where a = b + 1.

13. The liquid detection device according to any one of claims 1-10, characterized in that, The test paper is colloidal gold test paper, dry chemical test paper, or fluorescent test paper.

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