Small specimen sampling device

By designing a small specimen collection device consisting of a fixed-shape paper bag and easily breakable or water-soluble staining capsules, the problems of cumbersome specimen collection and contamination loss were solved, achieving an efficient and convenient specimen staining and wrapping process.

CN223650275UActive Publication Date: 2025-12-09SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV
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Patent Information

Application Number
CN202423125761.8
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-17
Publication Date
2025-12-09
Estimated Expiration
2034-12-17

AI Technical Summary

Technical Problem

In existing technologies, the process of collecting small specimens is cumbersome and can easily lead to tissue loss and contamination. In particular, due to the small amount of tissue, the shape and wrapping method of the embedding paper are not fixed, which makes the operation difficult. Furthermore, the process of adding staining solution can easily cause specimen contamination and loss.

Method used

Design a small specimen collection device that includes a paper bag and a staining capsule. The paper bag has a fixed-shaped opening and contains a staining capsule. The staining capsule is a fragile or water-soluble capsule. After the small specimen is placed through the opening, the staining capsule is pressed to allow the staining solution to flow out, simplifying the operation and preventing contamination and loss.

Benefits of technology

It improves material collection efficiency, reduces tissue loss and contamination, is easy to operate, has a fixed wrapping method, makes the dyeing process more reliable, and avoids the trouble caused by manual folding.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of medical instruments, and discloses a small specimen sampling device which comprises a paper bag and a dyeing capsule, the paper bag is provided with a bag opening, the dyeing capsule is arranged in the paper bag, the dyeing capsule is filled with dyeing liquid, the dyeing liquid is used for dyeing a small specimen, and the dyeing capsule is an easily-broken capsule or a water-soluble capsule. Small specimens can be put into the paper bag from the bag opening, the small specimens can be wrapped without folding by adopting the paper bag, the operation is convenient, the efficiency is high, the small specimens are not easy to lose, the paper bag shape and the wrapping mode are fixed, and the small specimens are easy to take out after dehydration. After a small specimen is placed in the paper bag, the paper bag is pressed to crush the dyeing capsule, so that the dyeing liquid flows out, the small specimen is dyed with the dyeing liquid, when the dyeing capsule is a water-soluble capsule, the dyeing capsule is broken when encountering water carried by the small specimen, the dyeing liquid flows out for dyeing, and specimen pollution and loss caused by dripping of the dyeing liquid are prevented.
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Description

Technical Field

[0001] This utility model relates to the field of medical device technology, and in particular to a small specimen collection device. Background Technology

[0002] Currently, the hospital's pathology department receives tissue specimens from across the hospital. Among these, core needle aspiration and fine needle biopsy specimens, endoscopic specimens such as those from gastrointestinal endoscopy and colonoscopy, and cervical biopsy specimens are referred to as small specimens. These small specimens are typically about 1cm × 0.1cm × 0.1cm in size. Pathological diagnosis of these small specimens is crucial, as most require determining the benign or malignant nature of the lesion, directly impacting the patient's next treatment plan. These small specimens are exceptionally valuable due to their small volume, and because of this, pathologists and technicians must exercise extreme caution during the sampling and dehydration processes. Any tissue loss or contamination would be a major liability incident.

[0003] Because the tissues are so small, directly placing them into a perforated embedding cassette would result in tissue loss. Therefore, in pathology, the current procedure for collecting such small specimens involves first placing the tissue on embedding paper, applying eosin (the staining agent), wrapping the tissue with the embedding paper, and then placing it in an embedding cassette for further dehydration. The process for collecting small specimens involves numerous manual steps: selecting embedding paper, placing the tissue, applying eosin, wrapping the tissue, and placing it in the embedding cassette. This is very tedious and significantly impacts the work schedule.

[0004] Furthermore, the embedding paper currently being purchased is quite large. After being purchased, the technical team cuts it into smaller pieces with a utility knife. The size and shape of the cut pieces are not fixed (they are mostly square or diamond-shaped), and sometimes the sampling doctors cannot select suitable paper. Moreover, different sampling doctors use different methods to wrap tissue with the embedding paper. Some place the tissue in the center of the paper, fold it along one diagonal, then fold the other two corners towards the center, and finally fold the two folded corners towards the center again. Others place the tissue in the center of the paper and roll up the embedding paper with tweezers. Still others place the tissue and wrap it in a very arbitrary way. In short, the shape of the embedding paper is not fixed, and the way the tissue is wrapped varies from person to person. All of these factors bring difficulties to the sampling doctors and subsequent work (because the embedding paper needs to be opened later to embed and impregnate the tissue with paraffin).

[0005] In addition, when multiple small specimens need to be collected at the same time, spreading out multiple small embedding papers on the sampling table at the same time can easily cause tissue loss and contamination. When using a pipette to draw eosin from the bottle and drop it onto the tissue, and then putting the pipette back into the bottle, this process has to be repeated for each small specimen. During this process, it is very likely that small tissues will be accidentally sucked into the pipette because the pipette opening is too close to the tissue, resulting in the loss of the tissue specimen. Utility Model Content

[0006] The purpose of this invention is to provide a small specimen collection device that is highly efficient and reduces tissue loss and contamination.

[0007] To achieve the above objectives, this utility model provides a small specimen collection device, including a paper bag and a staining capsule. The paper bag has an opening, and the staining capsule is placed inside the paper bag. The staining capsule is filled with a staining solution, which is used to stain the small specimen. The staining capsule is an easily breakable capsule or a water-soluble capsule.

[0008] As a preferred embodiment, the paper bag includes a bag body, which includes a first bag piece and a second bag piece. The bottom, left and right portions of the first bag piece and the second bag piece are connected, while the top portions of the first bag piece and the second bag piece are not connected to form the bag opening.

[0009] As a preferred embodiment, the paper bag includes a bag body, which has a trapezoidal structure, and the bag opening is located on the side of the bag body with the longer bottom edge.

[0010] As a preferred embodiment, the paper bag includes a bag body and a bag flap, the bag flap being formed by folding an extension of the upper part of the bag body and used to cover the bag opening.

[0011] As a preferred embodiment, the paper bag further includes a fixing strip, the two ends of which are respectively connected to the outer side of the bag body, and the fixing strip and the bag body form an opening through which the bag cover can be inserted.

[0012] As a preferred embodiment, the bag body includes a first bag piece and a second bag piece. The bottom, left and right portions of the first bag piece and the second bag piece are connected, but the upper portions of the first bag piece and the second bag piece are not connected to form the bag opening. The length of the first bag piece is greater than the length of the second bag piece, so that the portion of the upper portion of the first bag piece that extends beyond the second bag piece forms the bag cover.

[0013] As a preferred embodiment, the first bag piece includes a body and a bag cap. Both the body and the second bag piece are trapezoidal structures. The body and the bottom, left and right sides of the second bag piece are connected. The body and the top of the second bag piece are not connected to form the bag opening. The top of both the body and the second bag piece has a longer bottom edge. The bag cap is connected to the top of the body.

[0014] As a preferred embodiment, the two inner sides of the paper bag are respectively provided with a protrusion and a recess, and the protrusion and the recess are fitted together.

[0015] As a preferred option, the staining solution is eosin.

[0016] As a preferred embodiment, the dyeing capsule is a water-soluble capsule, and the dyeing capsule includes a water-soluble film, which is a PVA film.

[0017] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0018] This invention utilizes a paper bag with a pre-filled opening, allowing small specimens to be placed inside. The paper bag eliminates the need for folding, making the process convenient, efficient, and less prone to loss. Furthermore, the paper bags are mass-produced with a fixed shape and wrapping method, ensuring easy removal after dehydration. Inside the paper bag is a staining capsule filled with staining solution. The capsule can be either easily broken or water-soluble. When the specimen is placed in the bag, pressing the bag breaks the capsule, allowing the staining solution to flow out and stain the specimen. When the capsule is water-soluble, since the specimen is stored in a water-containing sample bottle, it will be wet when removed. Therefore, placing the specimen in the paper bag causes the capsule to break upon contact with water, allowing the staining solution to flow out and stain the specimen, preventing contamination and loss due to dripping staining solution. Attached Figure Description

[0019] Figure 1 This is a schematic diagram of the small specimen collection device according to Embodiment 1 of this utility model.

[0020] Figure 2 This is a schematic diagram of the small specimen collection device according to Embodiment 2 of this utility model.

[0021] Figure 3 This is a schematic diagram of the small specimen collection device according to Embodiment 3 of this utility model.

[0022] In the diagram, 1-paper bag; 101-bag opening; 102-first bag piece; 1021-bag cap; 1022-body part; 103-second bag piece; 104-protrusion; 105-recess; 2-dyed capsule. Detailed Implementation

[0023] The specific embodiments of this utility model will be described in further detail below with reference to the accompanying drawings and examples. The following examples are used to illustrate this utility model, but are not intended to limit its scope.

[0024] In the description of this utility model, it should be noted that the terms "center," "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description. They do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation on this utility model. In addition, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0025] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0026] Furthermore, in the description of this utility model, unless otherwise stated, "a plurality of" means two or more.

[0027] Example 1

[0028] like Figure 1 As shown, a preferred embodiment of the present invention provides a small specimen collection device, comprising a paper bag 1 and a staining capsule 2. The paper bag 1 has a bag opening 101, and the staining capsule 2 is disposed inside the paper bag 1. The staining capsule 2 is filled with staining solution, which is used to stain the small specimen. The staining capsule 2 is an easily breakable capsule or a water-soluble capsule. This embodiment uses a paper bag 1 with a bag opening 101. Small specimens can be placed into the paper bag 1 through the bag opening 101. Using the paper bag 1, the small specimens can be wrapped without folding, which is convenient, efficient, and less likely to be lost. Moreover, the paper bag 1 is mass-produced with a fixed shape and wrapping method, and it is easy to remove after dehydration. A staining capsule 2 is placed inside the paper bag 1. The staining capsule 2 is filled with staining solution. The staining capsule 2 is an easily breakable capsule or a water-soluble capsule. When the small specimen is placed into the paper bag 1, pressing the paper bag 1 will break the staining capsule 2, allowing the staining solution to flow out and stain the small specimen. When the staining capsule 2 is a water-soluble capsule, since the small specimen is stored in a sample bottle containing water, the small specimen will be wet when it is taken out of the sample bottle. Therefore, when the small specimen is placed into the paper bag 1, the staining capsule 2 will break upon contact with water, allowing the staining solution to flow out for staining, preventing specimen contamination and loss caused by dripping staining solution.

[0029] In this embodiment, the paper bag 1 includes a bag body, which includes a first bag piece 102 and a second bag piece 103. The bottom, left, and right sides of the first bag piece 102 and the second bag piece 103 are connected, while the top parts of the first bag piece 102 and the second bag piece 103 are not connected to form a bag opening 101. In this embodiment, the paper bag 1 is made by folding a piece of paper in half and pressing the two sides together, thereby connecting the bottom, left, and right sides of the first bag piece 102 and the second bag piece 103 while leaving the top parts unconnected. The first bag piece 102 and the second bag piece 103 are mechanically connected, reducing the use of adhesives and avoiding the addition of other substances during the specimen staining process.

[0030] Furthermore, the paper bag 1 in this embodiment includes a bag body with a trapezoidal structure. The bag opening 101 is located on the side with the longer bottom edge of the bag body. That is, the upper length of the bag body is greater than the lower length. The longer bottom edge of the bag body is the bag opening 101, which facilitates the placement of specimens into the paper bag 1. After the staining capsule 2 is placed into the paper bag 1, the staining capsule 2 is located on the side with the shorter bottom edge of the bag body (i.e., the lower part of the bag body). In this embodiment, the length of the staining capsule 2 is 1-3 mm shorter than the lower part of the bag body. Due to the small gap, the staining capsule 2 can be secured at the lower part of the bag body, preventing the staining capsule 2 from falling out of the paper bag 1. More specifically, the paper bag 1 in this embodiment has an isosceles trapezoidal structure. The length of the upper part of the bag body is more than twice the length of the lower part of the bag body. Setting the upper part of the bag body, where the bag opening 101 is located, to be longer makes it easier to place small specimens into the paper bag 1.

[0031] The paper bag material in this embodiment is the same as the wrapping paper.

[0032] Example 2

[0033] The difference between this embodiment and Embodiment 1 is that, based on Embodiment 1, this embodiment further explains the structure of the paper bag 1.

[0034] like Figure 2As shown, the paper bag 1 in this embodiment includes a bag body and a bag lid 1021. The bag lid 1021 is formed by folding the upper part of the bag body and is used to cover the bag opening 101. The bag lid 1021 further prevents small specimens from being lost after being placed in the paper bag 1. Furthermore, since the small specimens are small, the paper bag 1 in this embodiment is also small. By adding the bag lid 1021, when placing the small specimen, the bag lid 1021 is first held against the surface, and then the second bag flap 103 is lifted, thus facilitating the opening of the bag opening 101 and increasing the ease of placing the small specimen into the bag opening 101. Moreover, after the small specimen is placed in the paper bag 1, the bag lid 1021 is closed, which also prevents the staining solution from splashing out when the staining capsule 2 breaks, maintaining the sampling environment and allowing the staining solution to contact the small specimen as much as possible. In this embodiment, the bag cover 1021 is formed by extending and folding the upper part of the bag body. Only a portion of the upper part of the bag body needs to be extended to form the bag cover 1021. The bag cover 1021 is integral with the bag body, which reduces the connection steps between the bag cover 1021 and the bag body when setting the bag cover 1021 separately, thus reducing costs.

[0035] Optionally, the paper bag 1 also includes a fixing strip, the two ends of which are connected to the outer side of the bag body, forming an opening through which the bag cover 1021 can be inserted. The bag cover 1021 passes between the fixing strip and the outer side of the bag body, thereby securing the bag cover 1021.

[0036] Specifically, the bag body in this embodiment includes a first bag piece 102 and a second bag piece 103. The bottom, left, and right portions of the first bag piece 102 and the second bag piece 103 are connected, while the upper portions of the first bag piece 102 and the second bag piece 103 are not connected to form a bag opening 101. The length of the first bag piece 102 is greater than the length of the second bag piece 103, so that the portion of the upper part of the first bag piece 102 that extends beyond the second bag piece 103 forms a bag flap 1021. The bag flap 1021 is integral with the first bag piece 102.

[0037] Furthermore, the first bag piece 102 includes a body portion 1022 and a bag flap 1021. Both the body portion 1022 and the second bag piece 103 are trapezoidal structures. The bottom, left, and right portions of the body portion 1022 and the second bag piece 103 are connected, while the upper portions of the body portion 1022 and the second bag piece 103 are not connected to form the bag opening 101. The upper portions of both the body portion 1022 and the second bag piece 103 have their respective base sides longer. The bag flap 1021 is connected to the upper portion of the body portion 1022. In this embodiment, the body portion 1022, the bag flap 1021, and the second bag piece 103 are trapezoidal structures of the same shape and size, and all three are isosceles trapezoids. The main body 1022, the bag cap 1021, and the second bag piece 103 are the same in shape and size. When the bag cap 1021 is closed, the bag cap 1021 will overlap the bottom of the second bag piece 103, which is the bottom of the entire bag body. Therefore, when the bag cap 1021 is closed, the dyeing capsule 2 can be squeezed at the same time, further improving efficiency.

[0038] The other structures in this embodiment are the same as in Embodiment 1, and will not be described again here.

[0039] Example 3

[0040] The difference between this embodiment and embodiment two is that, based on embodiment two, this embodiment provides a further explanation of paper bag 1.

[0041] like Figure 3 As shown, in this embodiment, the two opposite inner sides of the paper bag 1 are respectively provided with a protrusion 104 and a recess 105, and the protrusion 104 and the recess 105 are fitted together. In production, the recess 105 is pressed into the first bag sheet 102 and the protrusion 104 is pressed into the second bag sheet 103 by stamping. After the dye capsule 2 is placed into the paper bag 1, the protrusion 104 is pressed into the recess 105 to prevent the dye capsule 2 from falling off. Moreover, when placing a small specimen, the protrusion 104 can be dislodged from the recess 105 by opening the second bag sheet 103. In this embodiment, the protrusion 104 and the recess 105 are located in the middle of the paper bag 1.

[0042] The other structures in this embodiment are the same as in Embodiment 2, and will not be described again here.

[0043] Example 4

[0044] The difference between this embodiment and embodiment three is that, based on embodiment three, this embodiment further explains the dyeing capsule 2.

[0045] In this embodiment, the staining solution is eosin. It should be noted that the staining solution can be replaced with other staining solutions as needed for staining the specimen, such as hematoxylin, a mixture of hematoxylin and eosin, gentian violet, etc.

[0046] In this embodiment, the dyeing capsule 2 is a water-soluble capsule, which includes a water-soluble film, namely a PVA film. The PVA (polyvinyl alcohol) film has high water absorption and dissolves easily in water, thereby increasing the rupture rate of the dyeing capsule 2.

[0047] When the staining capsule 2 is an easily broken capsule, the capsule wall of the staining capsule 2 is designed to be thin so that the staining capsule 2 can be broken by pressing lightly, allowing the staining solution to flow out.

[0048] The other structures in this embodiment are the same as in Embodiment 3, and will not be described again here.

[0049] The working process of this utility model is as follows: Press the two sides of the paper bag 1 with two fingers and squeeze to make the first bag piece 102 and the second bag piece 103 of the paper bag 1 arch outward, the protrusion 104 comes out from the depression 105, the bag mouth 101 is open, after taking the small specimen out of the sample bottle with tweezers, put the small specimen into the paper bag 1 through the bag mouth 101, cover the bag with the bag cap 1021, when the bag cap 1021 covers the second bag piece 103, squeeze the staining capsule 2 at the bottom of the paper bag 1, the staining capsule 2 ruptures when it comes into contact with the water carried on the small specimen and the pressure, the staining solution flows out, so that the small specimen comes into contact with the staining solution, and then the paper bag 1 is put into the embedding box. After the dehydrator completes the tissue dehydration, the technical team performs tissue embedding and paraffin infiltration.

[0050] In summary, this utility model embodiment provides a small specimen collection device. It uses a paper bag 1 with a bag opening 101 to place small specimens into the paper bag 1. The paper bag 1 allows for easy wrapping of the small specimens without folding, making it convenient, efficient, and less prone to loss. Furthermore, the paper bag 1 is mass-produced with a fixed shape and wrapping method, making it easy to remove after dehydration. A staining capsule 2 filled with staining solution is placed inside the paper bag 1. The staining capsule 2 is either easily ruptured or water-soluble. When the small specimen is placed in the paper bag 1, pressing the paper bag 1 breaks the staining capsule 2, allowing the staining solution to flow out and stain the specimen. When the staining capsule 2 is water-soluble, since the small specimen is stored in a water-containing sample bottle, it will be wet when removed from the sample bottle. Therefore, when the small specimen is placed in the paper bag 1, the staining capsule 2 will break upon contact with water, allowing the staining solution to flow out for staining, preventing specimen contamination and loss due to dripping staining solution. The device used in this embodiment of the invention makes it convenient and easy to collect small specimens. The device is simple and practical, and it also eliminates the need to add eosin, which can reduce tissue loss and tissue contamination during the collection of small specimens.

[0051] The above description is only a preferred embodiment of the present utility model. It should be noted that for those skilled in the art, several improvements and substitutions can be made without departing from the technical principles of the present utility model, and these improvements and substitutions should also be considered within the protection scope of the present utility model.

Claims

1. A small specimen collection device, characterized in that, The invention includes a paper bag (1) and a staining capsule (2). The paper bag (1) has an opening (101). The staining capsule (2) is located inside the paper bag (1). The staining capsule (2) is filled with staining solution. The staining solution is used to stain small specimens. The staining capsule (2) is a perforated capsule or a water-soluble capsule.

2. The small specimen collection device according to claim 1, characterized in that, The paper bag (1) includes a bag body, which includes a first bag piece (102) and a second bag piece (103). The bottom, left and right sides of the first bag piece (102) and the second bag piece (103) are connected, while the top of the first bag piece (102) and the second bag piece (103) are not connected to form the bag opening (101).

3. The small specimen collection device according to claim 1, characterized in that, The paper bag (1) includes a bag body, which has a trapezoidal structure, and the bag opening (101) is located on the side of the bag body with the longer bottom edge.

4. The small specimen collection device according to claim 1, characterized in that, The paper bag (1) includes a bag body and a bag flap (1021), the bag flap (1021) being formed by folding the upper part of the bag body and used to cover the bag opening (101).

5. The small specimen collection device according to claim 4, characterized in that, The paper bag (1) also includes a fixing strip, the two ends of which are respectively connected to the outer side of the bag body, and the fixing strip and the bag body form an opening through which the bag cover (1021) can be inserted.

6. The small specimen collection device according to claim 4, characterized in that, The bag body includes a first bag piece (102) and a second bag piece (103). The bottom, left and right parts of the first bag piece (102) and the second bag piece (103) are connected. The upper parts of the first bag piece (102) and the second bag piece (103) are not connected to form the bag opening (101). The length of the first bag piece (102) is greater than the length of the second bag piece (103), so that the part of the upper part of the first bag piece (102) that extends beyond the second bag piece (103) forms the bag cover (1021).

7. The small specimen collection device according to claim 6, characterized in that, The first bag piece (102) includes a body part (1022) and a bag cover (1021). The body part (1022) and the second bag piece (103) are both trapezoidal structures. The bottom, left and right parts of the body part (1022) and the second bag piece (103) are connected. The upper part of the body part (1022) and the second bag piece (103) are not connected to form the bag opening (101). The upper parts of the body part (1022) and the second bag piece (103) are each the side with a longer bottom edge. The bag cover (1021) is connected to the upper part of the body part (1022).

8. The small specimen collection device according to claim 1, characterized in that, The paper bag (1) has a protrusion (104) and a recess (105) on its two opposite inner sides, and the protrusion (104) and the recess (105) are fitted together.

9. The small specimen collection device according to claim 1, characterized in that, The staining solution is eosin.

10. The small specimen collection device according to claim 1, characterized in that, The dyeing capsule (2) is a water-soluble capsule, and the dyeing capsule (2) includes a water-soluble film, which is a PVA film.