Simple magnetic bead separation nucleic acid extraction device

Abstract

The utility model belongs to the technical field of nucleic acid extraction equipment, and particularly relates to a simple magnetic bead separation nucleic acid extraction device which comprises a test tube placing plate, test tube placing holes are formed in the surface of the test tube placing plate, nucleic acid extraction test tubes are arranged in the test tube placing holes, and supporting plates are installed at the front end and the rear end of the lower surface of the test tube placing plate. The bottom end of the supporting plate is mounted on one side of the top end of the box body, a plate type electromagnet is arranged on one side of the nucleic acid extraction test tube and mounted on the outer wall of one side of a mounting plate, and the bottom end of the mounting plate is mounted at the top end of the box body. The nucleic acid extraction test tube is simple in overall structure, an operator can conveniently adsorb magnetic beads on the inner wall of one side of the nucleic acid extraction test tube to perform washing and elution operation, the operator does not need to manually operate a magnet to enable the magnetic beads to be adsorbed on the inner wall of one side of the nucleic acid extraction test tube, the operator can conveniently perform washing and elution operation, and the practicability is high.

Description

TECHNICAL FIELD

[0001] The utility model belongs to nucleic acid extraction equipment technical field especially, it relates to a simple and easy magnetic bead separation nucleic acid extraction device. BACKGROUND

[0002] At present, the most used nucleic acid extraction technology is magnetic bead separation nucleic acid extraction technology, when nucleic acid is extracted by using magnetic bead separation nucleac acid extraction technology, magnetic bead method nucleic acid extraction can be generally divided into four steps: lysis-coupling-washing-elution.

[0003] Through the search, patent announcement No. CN211420131U discloses a simple and easy magnetic bead separation nucleic acid extraction device, which comprises an incubator, a top plate is arranged on the top of the incubator, a heating assembly is arranged at the bottom of the incubator, the heating assembly comprises a heat conducting block, the inner side of the heat conducting block is fixedly connected with a heating pipe, a heating wire is sleeved on the surface of the heating pipe, a support plate is installed on one side of the top plate, a first pressing plate and a second pressing plate are slidably installed above the top plate, a first gear rack is installed on the first pressing plate, a second gear rack is installed on the second pressing plate, a first rotating shaft and a second rotating shaft are rotatably installed on the support plate, the first rotating shaft and the second rotating shaft are located on one side of the top plate and are respectively provided with a first gear and a second gear, the first gear and the first gear rack are meshed with each other, a temperature sensor is installed in the incubator, and a processor is installed outside the incubator. It can ensure that the incubator is constant temperature during cultivation, improve the quality and extraction efficiency of nucleic acid extraction, and also enable the cultivation device to be automatically closed, thereby avoiding temperature alternation with the outside.

[0004] The existing simple and easy magnetic bead separation nucleic acid extraction device is inconvenient for the operator to operate the pipette gun to mix and process the nucleic acid extraction test tube when the operator performs the washing and elution operation, and therefore a simple and easy magnetic bead separation nucleic acid extraction device is proposed to solve the existing problems. UTILITY MODEL CONTENTS

[0005] In view of the deficiencies of the prior art, the utility model provides a simple and easy magnetic bead separation nucleic acid extraction device to solve the problems in the background art.

[0006] To solve the above technical problems, the utility model provides the following technical scheme:

[0007] The utility model provides a simple nucleic acid extraction device of magnetic bead separation, including test tube placement plate, the surface of test tube placement plate is equipped with test tube placement hole, is provided with nucleic acid extraction test tube in test tube placement hole, the front and back both ends of test tube placement plate lower surface all are equipped with support plate, and the bottom of support plate is installed in the top one side of box, one side of nucleic acid extraction test tube is provided with plate type electromagnet, and plate type electromagnet is installed on one side outer wall of mounting plate, and the bottom of mounting plate is installed in the top of box, the bottom four corner places of box all are equipped with sucking disc, the other side top of box is sequentially provided with second power indicator, switch button and timer from left to right.

[0008] Further, the top and bottom of the plate type electromagnet are provided with a fixed ear on one side, and the fixed ear is fixedly connected with the mounting plate through a fastening bolt.

[0009] Further, an arc-shaped groove is formed on the outer wall of one side of the plate type electromagnet, and the inner wall of the arc-shaped groove is in contact with the outer wall of the nucleic acid extraction test tube.

[0010] Further, the inside bottom of the box is provided with a storage battery.

[0011] Further, the front wall of the box is provided with a first power indicator and a USB charging interface, and the first power indicator is located on one side of the USB charging interface.

[0012] Through the above technical scheme, the simple nucleic acid extraction device of magnetic bead separation provided by the utility model has at least the following beneficial effects:

[0013] 1. When the operator needs to perform washing and elution operations, the operator can make the plate type electromagnet be powered on through the switch button. After the plate type electromagnet is powered on, it has a certain magnetism. After the plate type electromagnet has magnetism, the magnetic beads are adsorbed on the outer wall of the nucleic acid extraction test tube in contact with the plate type electromagnet. When the magnetic beads do not need to be adsorbed, the operator only needs to power off the plate type electromagnet and lose the magnetism. Thus, the utility model is convenient for the operator to adsorb the magnetic beads on the inner wall of one side of the nucleic acid extraction test tube to perform washing and elution operations. The operator does not need to manually operate the magnet to adsorb the magnetic beads on the inner wall of one side of the nucleic acid extraction test tube. This facilitates the operator to hold the liquid handling gun to mix and process the fluid in the nucleic acid extraction test tube, and facilitates the operator to perform washing and elution operations.

[0014] 2. The utility model discloses a timer setting, when the fluid in the nucleic acid extraction test tube is washed or eluted and mixed, the fluid in the nucleic acid extraction test tube needs to be rested for a period of time, at this time, the operator can carry out timing operation through the timer, which is convenient for the operator to carry out subsequent operation, avoids the fluid after washing or elution and rests for too short time to cause the nucleic acid extraction effect to reduce, and has high practicality. BRIEF DESCRIPTION OF DRAWINGS

[0015] The accompanying drawings, which are included to provide a further understanding of the utility model, form a part of this application and are incorporated herein to constitute a part of the description:

[0016] Figure 1 The utility model provides a simple magnetic bead separation nucleic acid extraction device's three -dimensional structure schematic diagram Figure 1 ;

[0017] Figure 2 The utility model provides a simple magnetic bead separation nucleic acid extraction device's three -dimensional structure schematic diagram Figure 2 ;

[0018] Figure 3 The utility model provides a simple magnetic bead separation nucleic acid extraction device's front view internal structure schematic drawing;

[0019] Figure 4 The utility model provides a simple magnetic bead separation nucleic acid extraction device's plate type electromagnet structure schematic drawing;

[0020] Figure 5 The utility model provides a simple magnetic bead separation nucleic acid extraction device's test tube placement plate structure schematic drawing.

[0021] In the drawing: 1, nucleic acid extraction test tube;2, test tube placement plate;201, support plate;202, test tube placement hole;3, plate type electromagnet;301, fixed ear;302, arc recess;4, mounting plate;5, box;501, sucking disc;502, first power indicator;503, USB charging interface;504, second power indicator;505, switch button;506, timer;507, battery. DETAILED DESCRIPTION

[0022] The technical scheme in the utility model embodiments will be described clearly and completely below with reference to the accompanying drawings in the utility model embodiments. Obviously, the described embodiments are only part of the embodiments of the utility model and not all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of the utility model.

[0023] Please refer to Figures 1 to 5The utility model discloses a simple and easy magnetic bead separation nucleic acid extraction device mainly includes test tube placing plate 2: the surface of test tube placing plate 2 is seted up test tube placing hole 202, is provided with nucleic acid extraction test tube 1 in test tube placing hole 202, the front and rear both ends of test tube placing plate 2 lower surface all are installed with support plate 201, and the bottom end of support plate 201 is installed in the top end one side of box 5, and one side of nucleic acid extraction test tube 1 is provided with plate type electromagnet 3, and plate type electromagnet 3 is installed on one side outer wall of mounting plate 4, and the bottom end of mounting plate 4 is installed in the top end of box 5, and the bottom end four corners of box 5 all are installed with sucking disc 501, and the setting of sucking disc 501 is convenient for operating personnel and is adsorbed in the surface of workbench with the utility model whole, avoids the utility model whole and produces the condition of sliding on the workbench, strengthens the stability of the utility model whole when placing, and the other side of the top end of box 5 is sequentially provided with second power -on indicator 504, switch button 505 and timer 506 from left to right,

[0024] The one side of plate type electromagnet 3 top end and bottom end is installed with fixed lug 301, and the fixed lug 301 is fixedly connected with mounting plate 4 through fastening bolt, so that the maintenance personnel can disassemble, replace or maintain plate type electromagnet 3, the one side outer wall of plate type electromagnet 3 is provided with arc-shaped groove 302, the inner wall of arc-shaped groove 302 is in contact with the outer wall of nucleic acid extraction test tube 1, the inside bottom end of box 5 is installed with storage battery 507, the setting of storage battery 507, and the storage battery 507 can provide electric energy for the utility model, the front end wall of box 5 is provided with first power-on indicator 502 and USB charging interface 503, the setting of USB charging interface 503 can charge storage battery 507 through USB charging interface 503, and first power-on indicator 502 is located at one side of USB charging interface 503.

[0025] When the operator needs to carry out washing and elution operation, the operator makes the plate-shaped electromagnet 3 be powered on through the switch button 505, the plate-shaped electromagnet 3 has certain magnetism after being powered on, the plate-shaped electromagnet 3 has magnetism and then can adsorb the magnetic beads on the outer wall of the nucleic acid extraction test tube 1 in contact with the plate-shaped electromagnet 3, when the magnetic beads do not need to be adsorbed, the operator only needs to power off the plate-shaped electromagnet 3 and lose magnetism, so that the utility model is convenient for the operator to adsorb the magnetic beads on the inner wall of one side of the nucleic acid extraction test tube 1 to carry out washing and elution operation, the operator does not need to manually operate the magnet to make the magnetic beads adsorbed on the inner wall of one side of the nucleic acid extraction test tube 1, the operator is convenient to hold the liquid handling gun to mix and process the fluid in the nucleic acid extraction test tube 1, the operator is convenient to carry out washing and elution operation, when the fluid in the nucleic acid extraction test tube 1 is mixed and operated to wash or elute, the fluid in the nucleic acid extraction test tube 1 needs to be placed for a period of time, at this time, the operator can carry out timing operation through the timer 506, the operator is convenient to carry out subsequent operation, and the situation that the nucleic acid extraction effect is reduced due to that the fluid after washing or elution is placed for too short time is avoided.

[0026] It should be noted that the terms "comprising", "containing" or any other similar term are intended to encompass non-exclusive inclusions, such that a process, method, article, or apparatus that comprises a list of elements does not include those elements solely, but can also include other elements not expressly listed or inherent to such process, method, article, or apparatus.

[0027] Although the embodiments of the utility model have been shown and described, it can be understood by those skilled in the art that various changes, modifications, replacements and variations can be made to these embodiments without departing from the principles and spirits of the utility model, the scope of the utility model is defined by the appended claims and their equivalents.

Claims

1. A simple magnetic bead separation nucleic acid extraction device, characterized by, The utility model provides a nucleic acid extraction device, including test tube placement plate (2): the surface of test tube placement plate (2) is set with test tube placement hole (202), be provided with nucleic acid extraction test tube (1) in test tube placement hole (202), the front and rear both ends of test tube placement plate (2) lower surface are all installed with support plate (201), and the bottom end of support plate (201) is installed in the top end one side of box (5), one side of nucleic acid extraction test tube (1) is provided with plate electromagnet (3), plate electromagnet (3) is installed in one side outer wall of mounting plate (4), and the bottom end of mounting plate (4) is installed in the top end of box (5), the bottom end four corner places of box (5) all are installed with sucking disc (501), the other side top end of box (5) is sequentially provided with second power -on indicator (504), switch button (505) and timer (506) from left to right.

2. The simple magnetic bead separation nucleic acid extraction device according to claim 1, characterized by, The top end and the bottom end of the plate electromagnet (3) are provided with a fixed ear (301) on one side, and the fixed ear (301) is fixedly connected with the mounting plate (4) through a fastening bolt.

3. The simple magnetic bead separation nucleic acid extraction device according to claim 1, characterized by, An arc-shaped groove (302) is formed on the outer wall of one side of the plate electromagnet (3), and the inner wall of the arc-shaped groove (302) is in contact with the outer wall of the nucleic acid extraction test tube (1).

4. The simple magnetic bead separation nucleic acid extraction device according to claim 1, characterized by, The inside bottom end of the box (5) is provided with a storage battery (507).

5. The simple magnetic bead separation nucleic acid extraction device according to claim 1, characterized by, The front end wall of the box (5) is provided with a first power-on indicator (502) and a USB charging interface (503), and the first power-on indicator (502) is located on one side of the USB charging interface (503).

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