Resuscitation heating device for cell cryopreservation tube
By designing a cell cryopreservation tube resuscitation heating device, and using a placement plate and a limiting rod to stir the water in the tank, the problem of controlling the temperature difference between the inside and outside of the cryopreservation tube and the resuscitation rate was solved, achieving uniform heating and rapid resuscitation.
Patent Information
- Application Number
- CN202423233474.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-26
- Publication Date
- 2025-12-19
- Estimated Expiration
- 2034-12-26
AI Technical Summary
Traditional water bath heating methods result in large temperature differences between the inside and outside of cryopreservation tubes. During the thawing process, the temperature gradient affects cell survival rate, and the upward movement of hot water and downward movement of cold water make it difficult to control the thawing rate.
Design a cell cryopreservation tube revival heating device. The cryopreservation tube is made to sway left and right in a water tank by a placement plate, and the water in the tank is stirred by a limiting rod. Combined with a diversion plate, the water flow is promoted to avoid static water heat difference and uneven temperature.
Accelerate the thawing speed of materials inside cryovials, ensure uniform heating, prevent asynchronous thawing at the top and bottom, and improve cell thawing results.
Smart Images

Figure CN223688338U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model belongs to cell cryopreservation technical field, especially, relate to a cell cryopreservation tube recovery heating device. BACKGROUND
[0002] In biomedical research and clinical applications, long-term preservation of cell samples is crucial. Cell cryopreservation technology can effectively inhibit cell metabolic activity by placing cell samples in an ultra-low temperature environment (such as liquid nitrogen), prolonging cell life, and providing stable cell resources for subsequent experimental research and clinical applications. Traditional cell recovery methods mainly rely on water bath heating, i.e. immersing the cryopreservation tube in a constant temperature water bath at about 37°C. Although this method is simple and easy to implement, it still has some problems.
[0003] Firstly, water bath heating can cause uneven heating. When the cryopreservation tube is heated in water, due to the limited flowability of the water bath, it is easy to cause a large temperature difference between the inside and outside of the cryopreservation tube, resulting in a temperature gradient during cell recovery, affecting the recovery effect. In the water bath heating process, if the heated water is not stirred in time, the hot water will float up and the cold water will sink down, causing large temperature fluctuations in the upper and lower layers of water during the water bath process, making it difficult to accurately control the rate of cell recovery, which has a significant impact on cell survival rate.
[0004] Therefore, we provide a cell cryopreservation tube recovery heating device to solve the above problems. INVENTION CONTENTS
[0005] The utility model aims at providing a cell cryopreservation tube recovery heating device, through the action of the placement plate, the device can make the cryopreservation tube constantly shake left and right in the water tank while recovering and heating in the water tank. This setting can use the limiting rod to stir the water in the water tank while shaking the cryopreservation tube, making the materials inside the cryopreservation tube shake, which can more fully accept the external water temperature heating through the cryopreservation tube wall, thereby accelerating the recovery speed of the materials inside the cryopreservation tube, solving the problem of the existing cryopreservation tube in water heating, due to the limited flowability of the water bath, it is easy to cause a large temperature difference between the inside and outside of the cryopreservation tube, resulting in a temperature gradient during cell recovery, affecting the recovery effect.
[0006] To solve the above technical problems, the utility model is realized by the following technical scheme: the utility model is a cell cryopreservation tube recovery heating device, including the base, both sides of the base are fixed with the support;
[0007] The top end of the support is fixed with the sliding groove, and the sliding groove is connected with the sliding block on the top.
[0008] Two sliding blocks are fixed with the placement plate.
[0009] One end of the support is fixed with a motor, and the bottom of the support is fixed with a bearing;
[0010] The inner ring of the bearing is fixed with a transmission rod, one end of the transmission rod is fixed with an adjusting rod, and the adjusting rod is internally provided with an adjusting groove;
[0011] The motor output shaft penetrates the support, one end of the motor output shaft is fixed with a movable rod, and one end of the movable rod is fixed with a movable block;
[0012] The movable block slides in the adjusting groove;
[0013] One side of the sliding block is fixed with a moving rod, and the moving rod slides in the adjusting groove;
[0014] The upper surface of the base is movably connected with a water tank.
[0015] The utility model further sets up: the chute is "T" type structure, the sliding block inner wall and the chute top match.
[0016] The utility model further sets up: the both sides of chute are all opened limit slot, the both sides of sliding block inner wall are all fixed with limit block;
[0017] The limit block and the limit slot are slidably connected.
[0018] The utility model further sets up: the upper surface of placing plate is opened with a plurality of placing holes;
[0019] The top of the placing hole is fixed with a protective tube, and the bottom of the protective tube is fixed with a limiting rod away from the placing hole;
[0020] The bottom of the limiting rod is fixed with a placing tube, and the surface of the placing tube is provided with a plurality of through holes.
[0021] The utility model further sets up: the upper surface of base is fixed with a positioning block, and the bottom of the water tank is provided with a plurality of positioning holes;
[0022] The positioning block is matched with the positioning hole.
[0023] The utility model further sets up: the both sides of water tank are all fixed with a shunt plate, and one end of the shunt plate is fixed with a plurality of water outlets;
[0024] The shunt plate is connected with a water pump through a first water pipe away from the water outlet, and the input end of the water pump is connected with the water tank through a second water pipe.
[0025] The utility model further sets up: the bottom of the water tank is opened with a placing groove, and the installing plate is slidably connected in the placing groove;
[0026] One side of the installing plate is fixed with a plurality of heating rods.
[0027] The utility model has the following beneficial effects:
[0028] 1、 the utility model discloses the action of placing plate, this device can make the freeze -storage tube in the water tank recovers heating simultaneously, constantly shakes in the water tank left and right, this setting can use the water in water tank with the stirring of spacing rod, shakes the freeze -storage tube simultaneously, makes the material in the freeze -storage tube shake, can be more fully through the freeze -storage tube pipe wall and accept the heating of external water temperature, with this accelerates the recovery speed of freeze -storage tube internal material.
[0029] 2、 the utility model discloses the action of the shunt plate, this device further makes the water flow in the water tank, compared with recovering heating in the still water, avoids appearing the hot water in the still water and sinking, prevents the problem of the different thawing speed of the same freeze -storage tube upper end and lower end. BRIEF DESCRIPTION OF DRAWINGS
[0030] In order to more clearly illustrate the technical scheme of the embodiment of the utility model, the following will be needed to use the drawing of the embodiment to introduce briefly, obviously, the drawing in the following description only some embodiments of the utility model, for those skilled in the art, under the premise of not paying creative labor, can also obtain other drawings according to these drawings.
[0031] Figure 1 It is the structural diagram of a cell freeze -storage tube recovery heating device of the utility model.
[0032] Figure 2 It is the rear view angle structural diagram of the utility model.
[0033] Figure 3 It is the side view angle structural diagram of the utility model.
[0034] Figure 4 It is the base structure diagram of the utility model.
[0035] Figure 5 It is the water tank external structure diagram of the utility model Figure 4 It is the local enlarged view of A in the middle.
[0036] Figure 6 It is the water tank external structure diagram of the utility model
[0037] In the drawing, the component list represented by each sign is as follows:
[0038] 1-base, 2-bracket, 3-slots, 4-slides, 5-put the plate, 6-motor, 7-bearing, 8-transmission rod, 9-adjusting rod, 10-adjusting slot, 11-movable rod, 12-movable block, 13-moving rod, 14-water tank, 15-limiting groove, 16-limiting block, 17-put the hole, 18-protective tube, 19-limiting rod, 20-put the tube, 21-through hole, 22-positioning block, 23-positioning hole, 24-shunt plate, 25-water outlet, 26-water pump, 27-put the groove, 28-mounting plate, 29-heating rod. DETAILED DESCRIPTION
[0039] It should be noted that the embodiments and features in the embodiments in the present application can be combined with each other without conflict. The present application will be described in detail below with reference to the drawings and in combination with the embodiments.
[0040] It should be noted that, unless otherwise specified, all technical and scientific terms used in the present application have the same meaning as generally understood by those skilled in the art to which the present application belongs.
[0041] In the present application, unless otherwise stated, the orientation such as "up, down" is generally with respect to the direction shown in the drawings, or with respect to the vertical, perpendicular or gravity direction; similarly, for the convenience of understanding and description, "left, right" is generally with respect to the left and right shown in the drawings; "inner, outer" refers to the inner and outer of the contour of each component itself, but the above orientation words are not used to limit the present application.
[0042] Specific embodiment one, please refer to Figures 1-6 The utility model discloses a cell cryopreservation tube recovery heating device, including base 1, both sides of base 1 are fixed with bracket 2, the top of bracket 2 is fixed with the slot 3, and the top of slot 3 is slidably connected with slide 4, and two slides 4 are fixed with the put plate 5 between, one end of a bracket 2 is fixed with motor 6, and the bottom of bracket 2 is fixed with bearing 7, and the inner ring of bearing 7 is fixed with transmission rod 8, and one end of transmission rod 8 is fixed with adjusting rod 9, and adjusting rod 9 is internally provided with adjusting slot 10, and the output shaft of motor 6 penetrates bracket 2, and one end of the output shaft of motor 6 is fixed with movable rod 11, and one end of movable rod 11 is fixed with movable block 12, and movable block 12 slides in adjusting slot 10, and one side of slide 4 is fixed with moving rod 13, and moving rod 13 slides in adjusting slot 10, and the upper surface of base 1 is movably connected with water tank 14.
[0043] Specifically, the slot 3 is a "T" type structure, and the inner wall of the slide 4 is matched with the top of the slot 3.
[0044] Further, the slot 3 is provided with a limiting groove 15 on both sides, and the inner wall of the slide 4 is fixed with a limiting block 16 on both sides; the limiting block 16 is slidably connected with the limiting groove 15.
[0045] The operation process of the embodiment is as follows: in use, the cell cryopreservation tube needing resuscitation and heating is placed in the placement hole 17, the water tank 14 is filled with warm water at a suitable temperature, and the motor 6 is turned on. The output shaft of the motor 6 continuously rotates forward and reversely. When it rotates, the movable rod 11 at one end of the motor 6 is driven to rotate. When the movable rod 11 rotates, the movable block 12 at one end of the movable rod 11 slides in the adjusting groove 10 formed on the surface of the adjusting rod 9. At this time, the other end of the adjusting rod 9 drives the moving rod 13 inside to move. The moving rod 13 drives the sliding block 4 at one end thereof to slide to the other end of the sliding groove 3. When the sliding block 4 reaches the end, the output shaft of the motor 6 reversely rotates, that is, through the rotation of the movable rod 11 and the adjusting rod 9, the sliding block 4 is driven to move to the other end of the sliding groove 3. When the sliding block 4 moves, it drives the placement plate 5 and the cryopreservation tube inside to move in the water tank 14. The device can make the cryopreservation tube resuscitate and heat in the water tank 14 while continuously shaking left and right in the water tank 14. This arrangement can stir the water in the water tank 14 by the limiting rod 19 while shaking the cryopreservation tube, so that the material inside the cryopreservation tube is shaken, and the cryopreservation tube wall can more fully receive the external water heating to accelerate the resuscitation speed of the material inside the cryopreservation tube.
[0046] Specific embodiment two, please refer to Figures 3-6 On the basis of the specific embodiment one, a plurality of placement holes 17 are formed on the upper surface of the placement plate 5. The top of each placement hole 17 is fixed with a protective pipe 18. The bottom of the placement hole 17 away from the protective pipe 18 is fixed with a limiting rod 19. The upper surface of the base 1 is fixed with a positioning block 22. The bottom of the water tank 14 is provided with a plurality of positioning holes 23. The positioning block 22 is matched with the positioning hole 23.
[0047] Specifically, the water tank 14 is fixed with a flow dividing plate 24 on both sides. The flow dividing plate 24 is fixed with a plurality of water outlets 25 at one end. The flow dividing plate 24 is connected with a water pump 26 through a first water pipe at the end away from the water outlet 25. The input end of the water pump 26 is connected with the water tank 14 through a second water pipe.
[0048] Further, the bottom of the water tank 14 is provided with a placement groove 27. The installation plate 28 is slidably connected in the placement groove 27. The installation plate 28 is fixed with a plurality of heating rods 29 on one side.
[0049] The operation process of the embodiment is as follows: in use, the water pump 26 is turned on. The output end of the water pump 26 pumps the warm water in the water tank 14 into the flow dividing plate 24, and then sprays out through the water outlets 25 arranged on both sides of the water tank 14 to spray the outer wall of the cryopreservation tube. The device further makes the water in the water tank 14 flow. Compared with resuscitation and heating in still water, the device avoids the situation that hot water floats and cold water sinks in still water, and prevents the problem that the upper and lower ends of the same cryopreservation tube thaw out asynchronously.
[0050] In the description of the specification, the description of the terms "one embodiment", "an example", "a specific example" and the like means that the specific features, structures, materials or characteristics described in connection with the embodiment or example are included in at least one embodiment or example of the utility model. In the specification, the illustrative description of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.
[0051] The preferred embodiments of the utility model disclosed above are only used for helping to set forth the utility model. The preferred embodiments do not describe all the details exhaustively, and also do not limit the utility model to only the specific implementation manners described. Obviously, according to the content of the specification, many modifications and changes can be made. The specification selects and specifically describes these embodiments, in order to better explain the principles and practical applications of the utility model, so that the persons skilled in the art can well understand and utilize the utility model. The utility model is limited only by the claims and the whole scope and equivalents thereof.
Claims
1. A cell cryo tube thawing and heating device comprising a base (1) characterised in that: Both sides of the base (1) are fixed with support (2); The top of the support (2) is fixed with a sliding groove (3), and the top of the sliding groove (3) is slidably connected with a sliding block (4); The two sliding blocks (4) are fixed with a placing plate (5); One end of one of the supports (2) is fixed with a motor (6), and the bottom of the support (2) is fixed with a bearing (7); The inner ring of the bearing (7) is fixed with a transmission rod (8), one end of the transmission rod (8) is fixed with an adjusting rod (9), and the inside of the adjusting rod (9) is provided with an adjusting groove (10); The output shaft of the motor (6) penetrates the support (2), one end of the output shaft of the motor (6) is fixed with a movable rod (11), and one end of the movable rod (11) is fixed with a movable block (12); The movable block (12) slides in the adjusting groove (10); One side of one of the sliding blocks (4) is fixed with a moving rod (13), and the moving rod (13) slides in the adjusting groove (10); The upper surface of the base (1) is movably connected with a water tank (14).
2. The cell cryotube thawing device of claim 1, wherein, The sliding groove (3) is "T" shaped structure, the inner wall of the sliding block (4) matches the top of the sliding groove (3).
3. The cell cryo tube thawing and heating device of claim 1, wherein, The two sides of the sliding groove (3) are provided with limiting grooves (15), and the two sides of the inner wall of the sliding block (4) are fixed with limiting blocks (16); The limiting block (16) and the limiting groove (15) are slidably connected.
4. The cell cryotube thawing device of claim 1, wherein, The upper surface of the placing plate (5) is provided with a plurality of placing holes (17); The top of the placing hole (17) is fixed with a protective tube (18), and the bottom of the placing hole (17) away from the protective tube (18) is fixed with a limiting rod (19); The bottom of the limiting rod (19) is fixed with a placing tube (20), and the surface of the placing tube (20) is provided with a plurality of through holes (21).
5. The cell cryo tube thawing and heating device of claim 1, wherein, The upper surface of the base (1) is fixed with a positioning block (22), and the bottom of the water tank (14) is provided with a plurality of positioning holes (23); The positioning block (22) matches the positioning hole (23).
6. The cell cryotube thawing device of claim 1, wherein, The two sides of the water tank (14) are fixed with a shunt plate (24), and one end of the shunt plate (24) is fixed with a plurality of water outlets (25); One end of the shunt plate (24) away from the water outlet (25) is connected with a water pump (26) through a first water pipe, and the input end of the water pump (26) is connected with the water tank (14) through a second water pipe.
7. The cell cryotube thawing and heating device of claim 1, wherein, The bottom of the water tank (14) is provided with a placing groove (27), and the inside of the placing groove (27) is slidably connected with a mounting plate (28); One side of the mounting plate (28) is fixed with a plurality of heating rods (29).