Sample storing and taking device for prostatic cancer PCA3 detection

Abstract

The utility model discloses a prostate cancer PCA3 detection sample storing and taking device which comprises a cylinder, a piston is slidably connected to the interior of the cylinder, a pull rod is connected to the piston, a pressing plate is connected to the end, extending out of the cylinder, of the pull rod, an adjusting ring is connected to the outer side wall of the cylinder, an adjusting rod is arranged in the adjusting ring in a penetrating mode, and the pressing plate is connected to the outer side wall of the cylinder. The adjusting ring is provided with a positioning piece used for limiting sliding of the adjusting rod, one end of the adjusting rod is connected with a limiting block, and the outer side wall of the drawing rod is connected with a positioning block used for abutting against the limiting block. According to the volume of a sample needing to be sucked, the position of the adjusting rod is adjusted, a worker pulls the drawing rod through the pressing plate to suck the sample, and when the sample in the barrel reaches the specific volume, the positioning block on the drawing rod abuts against the limiting block to limit the piston to continue to move, so that the sample of the specific volume is quickly sucked, the structure is accurate, and operation is convenient. Efficiency is high, and time and labor are saved.

Description

TECHNICAL FIELD

[0001] The present application relates to the field of biological experimental equipment, and particularly to a sample access device for prostate cancer PCA3 detection. BACKGROUND

[0002] PCA3 is a new prostate cancer antigen 3. Generally, PCA3 test requires collecting 20-30 ml of the first segment of the excreted urine after DRE. About 2 ml of the urine sample is placed in a transport test tube containing a dissolution buffer containing a ribonuclease inhibitor (if there is no inhibitor, mRNA will be destroyed within 20 minutes). The transport test tube is sent to a special laboratory overnight at room temperature (which can also be frozen). Some authors use urine sediment instead of urine samples to check all cells and cell fragments, and generally use urine samples. In the prior art, the urine sample needs to be filled into the test tube, and the test tube is used as a storage device. However, a cover, a cap or a plug needs to be added during transportation to prevent the sample from spilling out. Not only is the operation cumbersome, but it is also easy to contaminate hands or objects, which is very inconvenient.

[0003] At present, a patent with publication number CN214503015U discloses a sample access device for prostate cancer PCA3 detection, which comprises an inner cylinder and an outer cylinder which is selectively adjusted outside the inner cylinder. The outer cylinder is extended outside the inner cylinder at the upper end of the inner cylinder. A piston is installed inside the inner cylinder. The upper end of the piston is fixed with a pull rod. The end of the pull rod extending out of the inner cylinder is provided with a squeezing handle. The lower end of the outer cylinder is provided with an outer cylinder end plate. The lower end of the inner cylinder is provided with an inner cylinder end plate. A first eccentric hole is arranged on the outer cylinder end plate. A second eccentric hole which can be aligned with the first eccentric hole is arranged on the inner cylinder end plate. The lower end of the outer cylinder is provided with a liquid outlet nozzle which is in communication with the first eccentric hole.

[0004] For the above-mentioned related technology, the inventors believe that the following defects exist: when the detection personnel sucks the sample through the above-mentioned access device, the specific volume of the sample cannot be quickly and accurately sucked, which may lead to insufficient or excessive volume of the sucked sample, and the efficiency is low, so it needs to be improved. CONTENT OF THE UTILITY MODEL

[0005] In view of the defects of the prior art, the present application provides a sample access device for prostate cancer PCA3 detection, which aims to solve the above-mentioned problems.

[0006] A sample access device for prostate cancer PCA3 detection, comprising a cylinder, a piston slidably connected in the cylinder, a pull rod connected to the piston, a pressing plate connected to the end of the pull rod extending out of the cylinder, an adjusting ring connected to the outer sidewall of the cylinder, an adjusting rod penetrating through the adjusting ring, a positioning member installed on the adjusting ring for limiting the sliding of the adjusting rod, a limiting block connected to one end of the adjusting rod, and a positioning block connected to the outer sidewall of the pull rod for abutting against the limiting block.

[0007] By adopting the technical scheme, the position of the adjusting rod is adjusted according to the volume of the sample to be sucked, the staff pulls the pull rod by pressing the plate, the sample is sucked, when the sample in the barrel reaches a specific volume, the positioning block on the pull rod is in contact with the limiting block, the movement of the piston is limited, the specific volume of the sample is quickly completed, the structure is accurate, the efficiency is high, and time and labor are saved.

[0008] Optionally, the positioning member comprises a positioning plate, a positioning column and at least two elastic columns, the adjusting ring is provided with a positioning groove for clamping the positioning plate, the bottom wall of the positioning groove is provided with a through hole for the positioning column to pass through and at least two limiting grooves for clamping the elastic columns, the circumferential outer side wall of the elastic column is in close contact with the circumferential inner side wall of the limiting groove, and the outer side wall of the adjusting rod is provided with at least two adjusting holes for inserting the positioning column along the length direction of the adjusting rod.

[0009] By adopting the technical scheme, after the position of the adjusting rod is adjusted, the positioning plate is clamped into the positioning groove, and the positioning column on the positioning plate is sequentially inserted into the through hole and the limiting groove, and the elastic column on the positioning plate is clamped into the limiting groove, so that the positioning plate is prevented from being separated from the positioning groove.

[0010] Optionally, one end of the positioning column is connected with a semispherical guide block.

[0011] By adopting the technical scheme, the guide block can give the positioning column a guiding effect, so that the positioning column can be quickly inserted into the adjusting hole.

[0012] Optionally, the side, in contact with the limiting block, of the limiting block is connected with an elastic shock pad.

[0013] By adopting the technical scheme, the shock pad can buffer part of the impact force of the limiting block on the limiting block.

[0014] Optionally, a support strip is connected between the limiting block and the adjusting rod.

[0015] By adopting the technical scheme, the support strip can improve the connection firmness between the limiting block and the adjusting rod, so as to avoid the fracture between the limiting block and the adjusting rod as much as possible.

[0016] Optionally, the barrel is made of polypropylene material.

[0017] In summary, the present application has at least one of the following beneficial technical effects:

[0018] 1、According to the volume of the sample to be taken, adjust the position of the adjusting rod, the staff pulls the pull rod by pressing the plate, and the sample is taken, when the sample in the cylinder reaches a certain volume, the positioning block on the pull rod is in contact with the limiting block, which limits the piston to continue to move, thereby quickly completing the sample taking of a certain volume, the structure is accurate, efficient, time-saving and labor-saving.

[0019] 2、Adjust the position of the adjusting rod, then insert the positioning plate into the positioning groove, and at the same time make the positioning column on the positioning plate inserted into the through hole and the limiting groove in sequence, and the elastic column on the positioning plate is inserted into the limiting groove, thereby limiting the positioning plate from separating from the positioning groove.

[0020] 3、The support strip can improve the connection firmness between the limiting block and the adjusting rod, thereby avoiding the fracture between the limiting block and the adjusting rod as much as possible. BRIEF DESCRIPTION OF DRAWINGS

[0021] Figure 1 is a structural schematic diagram of an embodiment of the present application.

[0022] Figure 2 is an explosion schematic diagram of an embodiment of the present application.

[0023] Figure 3 is Figure 2 an enlarged schematic diagram of area A in

[0024] BRIEF DESCRIPTION OF DRAWINGS:

[0025] 1, cylinder; 2, support strip; 3, pull rod; 31, positioning block; 4, pressing plate; 5, adjusting ring; 51, positioning groove; 52, through hole; 53, limiting groove; 6, adjusting rod; 61, adjusting hole; 7, positioning piece; 71, positioning plate; 72, positioning column; 721, guide block; 73, elastic column; 8, limiting block; 81, shock pad. DETAILED DESCRIPTION

[0026] In order to facilitate the understanding of the present application, the present application will be described in more detail below in combination with the drawings and specific embodiments. It should be noted that when an element is described as "fixed to" another element, it can be directly on another element, or one or more intervening elements can be present therebetween. When an element is described as "connected" to another element, it can be directly connected to another element, or one or more intervening elements can be present therebetween. The terms "vertical", "horizontal", "left", "right" and similar expressions used in the present specification are only for illustrative purposes.

[0027] Unless otherwise defined, all technical and scientific terms used in the present disclosure have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used in the description of the application herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application. All publications, patent applications, patents, and other references mentioned in this specification are herein incorporated by reference in their entirety for the purpose of describing and disclosing, for example, the methodologies described in such publications that might be used in connection with the application.

[0028] The embodiments of the present application disclose a sample access device for prostate cancer PCA3 detection. Referring to Figure 1 and Figure 2 , the device comprises a barrel 1, a piston slidably connected in the barrel 1, a pull rod 3 fixedly connected to the piston, and a pressing plate 4 fixedly connected to an end of the pull rod 3 extending out of the barrel 1. The barrel 1 is made of polypropylene material, thus the barrel 1 has good chemical resistance and can resist most acids, alkalis and solvents.

[0029] Referring to Figure 2 and Figure 3 , an adjusting ring 5 is fixedly connected to an outer side wall of the barrel 1, an adjusting rod 6 is provided in the adjusting ring 5, a positioning member 7 for limiting sliding of the adjusting rod 6 is installed on the adjusting ring 5, a limiting block 8 is fixedly connected to one end of the adjusting rod 6, and a positioning block 31 for abutting against the limiting block 8 is fixedly connected to an outer side wall of the pull rod 3. The position of the adjusting rod 6 is adjusted according to the volume of the sample to be sucked, and the sample is sucked by pulling the pull rod 3 through the pressing plate 4. When the sample in the barrel 1 reaches a specific volume, the positioning block 31 on the pull rod 3 abuts against the limiting block 8, thereby limiting the piston from moving further, so that the sample of the specific volume is quickly sucked. The structure is accurate and efficient, and time and labor are saved.

[0030] Referring to Figure 2 and Figure 3 , the positioning member 7 comprises a positioning plate 71, a positioning column 72 and two elastic columns 73, and the elastic columns 73 are made of silica gel material. The adjusting ring 5 is provided with a positioning groove 51 for clamping the positioning plate 71, a through hole 52 for the positioning column 72 to pass through and two limiting grooves 53 for the elastic columns 73 to clamp are provided in a bottom wall of the positioning groove 51, the circumferential outer side wall of the elastic column 73 is close to the circumferential inner side wall of the limiting groove 53, and three adjusting holes 61 for the positioning column 72 to insert are provided in the outer side wall of the adjusting rod 6 along the length direction of the adjusting rod 6. After the position of the adjusting rod 6 is adjusted, the positioning plate 71 is clamped in the positioning groove 51, and the positioning column 72 on the positioning plate 71 is sequentially inserted into the through hole 52 and the limiting groove 53, and the elastic column 73 on the positioning plate 71 is clamped in the limiting groove 53, so as to limit the positioning plate 71 from separating from the positioning groove 51.

[0031] Referring to Figure 2 and Figure 3The end of the positioning column 72, away from the positioning plate 71, is fixedly connected with a semispherical guide block 721. The guide block 721 can provide a guide for the positioning column 72, thereby facilitating the quick insertion of the positioning column 72 into the adjusting hole 61.

[0032] With reference to Figure 2 and Figure 3 The side, in contact with the positioning block 31, of the limiting block 8 is fixedly connected with an elastic shock pad 81. Specifically, the shock pad 81 is made of silica gel. The shock pad 81 can buffer a part of the impact force of the positioning block 31 on the limiting block 8, thereby prolonging the service life of the positioning block 31 and the limiting block 8.

[0033] With reference to Figure 2 and Figure 3 The limiting block 8 and the adjusting rod 6 are fixedly connected with a support strip 2. The support strip 2 can improve the connection firmness between the limiting block 8 and the adjusting rod 6, thereby avoiding the breakage between the limiting block 8 and the adjusting rod 6 as much as possible.

[0034] The implementation principle of the sample access device for prostate cancer PCA3 detection according to the embodiment of the application is as follows: according to the volume of the sample to be sucked, the position of the adjusting rod 6 is adjusted, the sample is sucked by a worker through the pressing plate 4 to pull the pull rod 3, when the sample in the cylinder 1 reaches a specific volume, the positioning block 31 on the pull rod 3 is in contact with the limiting block 8, the movement of the piston is limited, thereby quickly completing the sample sucking of the specific volume, the structure is precise, the efficiency is high, and time and labor are saved.

[0035] The above are the preferred embodiments of the application, and do not limit the protection scope of the application, so that: all equivalent changes made according to the structure, shape, principle of the application should be covered in the protection scope of the application.

Claims

1. A sample storage and retrieval device for prostate cancer PCA3 detection, comprising a cylindrical body (1), a piston slidably connected inside the cylindrical body (1), a pull rod (3) connected to the piston, and a pressing plate (4) connected to one end of the pull rod (3) extending outside the cylindrical body (1), characterized in that: An adjusting ring (5) is connected to the outer wall of the cylinder (1). An adjusting rod (6) is inserted inside the adjusting ring (5). A positioning element (7) for limiting the sliding of the adjusting rod (6) is installed on the adjusting ring (5). A limit block (8) is connected to one end of the adjusting rod (6). A positioning block (31) for abutting against the limit block (8) is connected to the outer wall of the pull rod (3).

2. The sample storage and retrieval device for prostate cancer PCA3 detection according to claim 1, characterized in that: The positioning component (7) includes a positioning plate (71), a positioning post (72), and at least two elastic posts (73). The adjusting ring (5) has a positioning groove (51) for the positioning plate (71) to be inserted into. The bottom wall of the positioning groove (51) has a through hole (52) for the positioning post (72) to pass through and at least two limiting grooves (53) for the elastic posts (73) to be inserted into. The outer circumferential wall of the elastic post (73) is in close contact with the inner circumferential wall of the limiting groove (53). The outer wall of the adjusting rod (6) has at least two adjusting holes (61) spaced apart along the length of the adjusting rod (6) for the positioning post (72) to be inserted into.

3. The sample storage and retrieval device for prostate cancer PCA3 detection according to claim 2, characterized in that: One end of the positioning post (72) is connected to a hemispherical guide block (721).

4. The sample storage and retrieval device for prostate cancer PCA3 detection according to claim 1, characterized in that: The side of the limiting block (8) that contacts the positioning block (31) is connected to an elastic shock-absorbing pad (81).

5. A sample storage and retrieval device for prostate cancer PCA3 detection according to claim 1, characterized in that: A support bar (2) connects the limiting block (8) and the adjusting rod (6).

6. The sample storage and retrieval device for prostate cancer PCA3 detection according to claim 1, characterized in that: The cylinder (1) is made of polypropylene.

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