Autoimmune cell sorting kit

Abstract

The utility model discloses an autoimmune cell sorting kit which comprises a main body unit and a control unit, the main body unit comprises a box body, the top of the box body is rotatably connected with a box cover, a plurality of containing grooves are formed in the box body, and first rubber arc-shaped clamps and second rubber arc-shaped clamps are arranged in the containing grooves. When the box cover is opened to drive a connecting plate to rotate and an extrusion plate moves to no longer extrude a wedge-shaped pressed plate, a movable plate and a first rubber arc-shaped clamp are driven to move in the direction far away from a second rubber arc-shaped clamp under the resilience force of a second spring, so that the first rubber arc-shaped clamp and the second rubber arc-shaped clamp automatically loosen a reagent bottle; therefore, the reagent bottle can be conveniently taken out; when the box cover is covered, the box cover drives a connecting plate to rotate, the connecting plate rotates to drive an extruding plate to move, and when the extruding plate extrudes a wedge-shaped pressed plate, the extruding plate drives a moving plate and a first rubber arc-shaped clamp to move towards a direction close to a second rubber arc-shaped clamp, namely, when the box cover is covered, a reagent bottle can be automatically clamped.

Description

Technical Field

[0001] This invention relates to the field of reagent kit technology, and in particular to an autologous immune cell sorting reagent kit. Background Technology

[0002] Autologous immune cell sorting is an important biotechnology that involves isolating specific immune cells from a mixed cell population. This technology is significant for studying the function of immune cells, treating autoimmune diseases, and developing new treatment methods. Autologous immune cell sorting involves several steps and requires the use of reagent bottles, kits, and other tools for sample transport during the testing process.

[0003] Publication No. CN 209797984 U discloses a reagent kit for sorting CD8+ T cells using biological nanomagnetic beads. Two support plates are fixedly connected to opposite sides with arc-shaped clamps. A first spring is fixedly connected to the outer wall of the first and second telescopic rods. The end of the first spring away from the first and second telescopic rods is fixedly connected to the side wall of the support plate. This can effectively reduce the vibration force on the box and prevent damage to the reagent bottles inside, while also making it easy to pull the support plates.

[0004] The aforementioned patent uses a combination of arc-shaped clamps and springs to hold and fix reagent bottles. However, when placing the reagent bottles, it is necessary to move the corresponding clamps one by one to place the reagent bottle between two clamps. The same steps are required when taking them out. The state of the clamps cannot be automatically controlled according to the needs, making the operation cumbersome and impractical. Utility Model Content

[0005] (I) Purpose of the utility model

[0006] In view of this, the purpose of this utility model is to propose an autologous immune cell sorting kit. The technical problem to be solved is that existing kits require moving the corresponding clamps one by one when placing the reagent bottles in order to place the reagent bottles between two clamps. The same steps are required when taking them out. The state of the clamps cannot be automatically controlled according to the needs, which makes the operation cumbersome and the practicality poor.

[0007] (II) Technical Solution

[0008] To achieve the above technical objectives, this utility model provides an autologous immune cell sorting kit:

[0009] It includes a main unit and a control unit. The main unit includes a box body with a lid rotatably connected to the top. The box body has multiple storage slots, each containing a first and a second rubber arc-shaped clamp. A storage cylinder is fixed to the bottom inner wall of each storage slot. The control unit includes a rectangular rod. The box body has an inner cavity. Both ends of the rectangular rod are fixed to the inner walls of the inner cavity. A sliding rod is fixed to the side of the first rubber arc-shaped clamp away from the second rubber arc-shaped clamp. The sliding rod passes through the box body and slides within it. Two movable plates are slidably connected within the inner cavity. One end of the sliding rod extending into the inner cavity is fixed to the corresponding movable plate. The inner cavity is equipped with a drive assembly for moving the first rubber arc-shaped clamp. When the first rubber arc-shaped clamp approaches the second rubber arc-shaped clamp, it clamps the reagent bottle. When the first rubber arc-shaped clamp moves away from the second rubber arc-shaped clamp, it releases the reagent bottle.

[0010] Preferably, the driving assembly includes a pressing plate that slides on the outside of the rectangular rod, and a wedge-shaped pressure plate is fixed on one side of each of the two moving plates that are close to each other. The two sides of the pressing plate that are close to the wedge-shaped pressure plate are inclined surfaces.

[0011] Preferably, a first hinge seat is fixed to the top of the extrusion plate, and a second hinge seat is fixed to the inner wall of the box cover. A connecting plate is rotatably connected inside the first hinge seat, and the end of the connecting plate away from the first hinge seat is rotatably connected to the second hinge seat.

[0012] Preferably, a second spring is sleeved on the outer side of the slide rod, one end of the second spring abuts against the inner wall of the inner cavity, and the other end of the second spring abuts against the moving plate.

[0013] Preferably, a cylindrical body is fixed to the inner wall of the storage groove, and a column is slidably connected inside the cylindrical body. The end of the column away from the cylindrical body is fixed to a second rubber arc-shaped clamp.

[0014] Preferably, the cylinder body has multiple guide grooves, and the outer side of the column body has multiple guide rods fixed thereon, with the guide rods slidingly engaged in the corresponding guide grooves.

[0015] Preferably, a first spring is provided inside the cylinder, with one end of the first spring abutting against the column and the other end of the first spring abutting against the inner wall of the storage groove.

[0016] As can be seen from the above technical solutions, this application has the following beneficial effects:

[0017] 1. When it is necessary to remove the reagent bottle from the reagent kit, open the lid to make the connecting plate rotate. When the connecting plate rotates, it causes the squeezing plate to move away from the wedge-shaped pressure plate. When the squeezing plate moves to the point where it no longer squeezes the wedge-shaped pressure plate, the second spring's rebound force causes the moving plate and the first rubber arc clamp to move away from the second rubber arc clamp, so that the first rubber arc clamp and the second rubber arc clamp automatically release the reagent bottle, making it easy to remove the reagent bottle.

[0018] 2: When it is necessary to place the reagent bottle into the reagent kit, place the reagent bottle into the storage tube, and then close the lid to make the connecting plate rotate. When the connecting plate rotates, it causes the squeezing plate to move closer to the wedge-shaped pressure plate, so that the squeezing plate squeezes the wedge-shaped pressure plate. When the wedge-shaped pressure plate is squeezed, it causes the moving plate and the first rubber arc clamp to move closer to the second rubber arc clamp. That is, when the lid is closed, the reagent bottle can be automatically clamped to prevent the reagent bottle from being damaged.

[0019] 3: Due to the arrangement of the cylinder, column, and first spring, when the first and second rubber arc clamps hold the reagent bottle, the column moves into the cylinder and compresses the first spring. This process plays a buffering role, preventing the squeezing force between the first and second rubber arc clamps from damaging the reagent bottle. Attached Figure Description

[0020] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on the provided drawings without creative effort.

[0021] Figure 1 A schematic diagram of the structure of an autologous immune cell sorting kit provided by this utility model;

[0022] Figure 2 Another structural schematic diagram of an autologous immune cell sorting kit provided by this utility model;

[0023] Figure 3 Provided by this utility model Figure 2 Schematic diagram of the structure at point A;

[0024] Figure 4 A partial structural disassembly diagram of the box body provided by this utility model;

[0025] Figure 5 Provided by this utility model Figure 4 A schematic diagram of the structure at point B.

[0026] Figure Descriptions: 100, Main Unit; 101, Box Body; 102, Box Lid; 103, Storage Slot; 104, First Rubber Arc Clip; 105, Second Rubber Arc Clip; 106, Storage Cylinder; 107, Cylinder Body; 108, Column; 109, Guide Slot; 110, Guide Rod; 111, First Spring; 200, Control Unit; 201, Rectangular Rod; 202, Inner Cavity; 203, Extrusion Plate; 204, Sliding Rod; 205, Moving Plate; 206, Wedge-Shaped Pressure Plate; 207, First Hinge Seat; 208, Second Hinge Seat; 209, Connecting Plate; 210, Second Spring. Detailed Implementation

[0027] The following description is exemplary in nature and is not intended to limit the scope, application, or use of this disclosure. It should be understood that in all these figures, the same or similar reference numerals indicate the same or similar parts and features. The figures are merely schematic representations of the concept and principles of embodiments of this disclosure and do not necessarily show the specific dimensions and scale of the various embodiments of this disclosure. Certain details or structures of embodiments of this disclosure may be exaggerated in particular portions of certain figures.

[0028] Reference Figure 1-5 :

[0029] In one embodiment of this utility model, an autologous immune cell sorting kit is provided, including a main unit 100 and a control unit 200. The main unit 100 includes a box body 101, with a box cover 102 rotatably connected to the top of the box body 101. Multiple storage slots 103 are provided inside the box body 101, and a first rubber arc-shaped clamp 104 and a second rubber arc-shaped clamp 105 are disposed within each storage slot 103. A storage cylinder 106 is fixed to the inner wall of the bottom of the storage slot 103. The control unit 200 includes a rectangular rod 201, and an inner cavity 202 is provided inside the box body 101. The two ends of the rectangular rod 201 are fixed to the inner walls on both sides of the inner cavity 202. A sliding rod 204 is fixed to the side of the rubber arc clamp 104 away from the second rubber arc clamp 105. The sliding rod 204 passes through the box body 101 and slides within the box body 101. Two moving plates 205 are slidably connected within the inner cavity 202. One end of the sliding rod 204 extending into the inner cavity 202 is fixed to the corresponding moving plate 205. A driving component for driving the first rubber arc clamp 104 to move is provided within the inner cavity 202. When the first rubber arc clamp 104 moves closer to the second rubber arc clamp 105, it can clamp the reagent bottle. When the first rubber arc clamp 104 moves away from the second rubber arc clamp 105, it can release the reagent bottle.

[0030] The drive assembly includes a pressing plate 203 that slides on the outside of a rectangular rod 201. Two moving plates 205 are fixed with wedge-shaped pressure plates 206 on their sides that are close to each other. The pressing plate 203 has inclined surfaces on both sides near the wedge-shaped pressure plates 206. A first hinge seat 207 is fixed to the top of the pressing plate 203. A second hinge seat 208 is fixed to the inner wall of the cover 102. A connecting plate 209 is rotatably connected inside the first hinge seat 207. One end of the connecting plate 209 away from the first hinge seat 207 is rotatably connected to the second hinge seat 208. A second spring 210 is sleeved on the outside of the slide rod 204. One end of the second spring 210 abuts against the inner wall of the inner cavity 202, and the other end of the second spring 210 abuts against the moving plate 205.

[0031] In use, when it is necessary to remove the reagent bottle from the reagent kit, first open the lid 102. When the lid 102 is opened, it causes the connecting plate 209 to rotate. As the connecting plate 209 rotates, it causes the squeezing plate 203 to move away from the wedge-shaped pressure plate 206. When the squeezing plate 203 moves to the point where it no longer squeezes the wedge-shaped pressure plate 206, the second spring 210, under its restoring force, causes the moving plate 205 to move. This causes the moving plate 205 to move the first rubber arc-shaped clamp 104 away from the second rubber arc-shaped clamp 105, thus automatically releasing the reagent bottle from the first and second rubber arc-shaped clamps, making it easy to remove the reagent bottle. When it is necessary to put the reagent bottle back into the reagent kit, when the lid is opened... After closing the lid 102, place the reagent bottle into the storage tube 106, and then close the lid 102 again. When the lid 102 is closed, it will cause the connecting plate 209 to rotate. When the connecting plate 209 rotates, it will cause the squeezing plate 203 to move closer to the wedge-shaped pressure plate 206, so that the squeezing plate 203 squeezes the wedge-shaped pressure plate 206. When the wedge-shaped pressure plate 206 is squeezed, it will cause the moving plate 205 and the sliding rod 204 to move. When the sliding rod 204 moves, it will cause the first rubber arc clamp 104 to move closer to the second rubber arc clamp 105, so that the first rubber arc clamp 104 and the second rubber arc clamp 105 clamp the reagent bottle tightly. That is, when the lid 102 is closed, the reagent bottle can be automatically clamped to avoid damage to the reagent bottle.

[0032] In addition, a cylindrical body 107 is fixed to the inner wall of the storage groove 103, and a column 108 is slidably connected inside the cylindrical body 107. One end of the column 108 away from the cylindrical body 107 is fixed to the second rubber arc-shaped clamp 105. Multiple guide grooves 109 are opened inside the cylindrical body 107, and multiple guide rods 110 are fixed to the outside of the column 108. The guide rods 110 are slidably engaged in the corresponding guide grooves 109. A first spring 111 is provided inside the cylindrical body 107. One end of the first spring 111 abuts against the column 108, and the other end of the first spring 111 abuts against the inner wall of the storage groove 103.

[0033] It should be noted that, due to the arrangement of the cylinder 107, the column 108, and the first spring 111, when the first rubber arc clamp 104 moves and comes into contact with the reagent bottle, the reagent bottle moves closer to the second rubber arc clamp 105 and squeezes the second rubber arc clamp 105. This causes the second rubber arc clamp 105 to move the column 108 into the cylinder 107 and compress the first spring 111. As a result, the first rubber arc clamp 104 and the second rubber arc clamp 105 clamp the reagent bottle. The process of the column 108 moving into the cylinder 107 and compressing the first spring 111 plays a buffering role, preventing the squeezing force between the first rubber arc clamp 104 and the second rubber arc clamp 105 from damaging the reagent bottle.

[0034] The exemplary implementation of the solution proposed in this disclosure has been described in detail above with reference to preferred embodiments. However, those skilled in the art will understand that various modifications and alterations can be made to the above specific embodiments without departing from the spirit of this disclosure, and various combinations can be made to the various technical features and structures proposed in this disclosure without exceeding the protection scope of this disclosure, which is determined by the appended claims.

Claims

1. An autologous immune cell sorting kit, characterized in that, include: The main unit (100) includes a box body (101), a box cover (102) is rotatably connected to the top of the box body (101), a plurality of storage slots (103) are provided inside the box body (101), a first rubber arc clip (104) and a second rubber arc clip (105) are provided in the storage slots (103), and a storage tube (106) is fixed to the bottom inner wall of the storage slots (103); The control unit (200) includes a rectangular rod (201). An inner cavity (202) is formed inside the housing (101). Both ends of the rectangular rod (201) are fixed to the inner walls of both sides of the inner cavity (202). A sliding rod (204) is fixed to the side of the first rubber arc-shaped clamp (104) away from the second rubber arc-shaped clamp (105). The sliding rod (204) passes through the housing (101) and slides within the housing (101). Two movable parts are slidably connected within the inner cavity (202). Plate (205), one end of the slide rod (204) extending into the inner cavity (202) is fixed to the corresponding moving plate (205), the inner cavity (202) is provided with a driving component for driving the first rubber arc clamp (104) to move, and when the first rubber arc clamp (104) moves closer to the second rubber arc clamp (105), it can clamp the reagent bottle, and when the first rubber arc clamp (104) moves away from the second rubber arc clamp (105), it can release the reagent bottle.

2. The autologous immune cell sorting kit according to claim 1, characterized in that, The drive assembly includes a pressing plate (203) that slides on the outside of a rectangular rod (201). Two moving plates (205) are each fixed with a wedge-shaped pressure plate (206) on the side that is close to each other. The pressing plate (203) has inclined surfaces on both sides near the wedge-shaped pressure plate (206).

3. The autologous immune cell sorting kit according to claim 2, characterized in that, The top of the extrusion plate (203) is fixed with a first hinge seat (207), and the inner wall of the box cover (102) is fixed with a second hinge seat (208). A connecting plate (209) is rotatably connected inside the first hinge seat (207), and the end of the connecting plate (209) away from the first hinge seat (207) is rotatably connected to the second hinge seat (208).

4. The autologous immune cell sorting kit according to claim 1, characterized in that, A second spring (210) is sleeved on the outside of the slide rod (204). One end of the second spring (210) abuts against the inner wall of the inner cavity (202), and the other end of the second spring (210) abuts against the moving plate (205).

5. The autologous immune cell sorting kit according to claim 1, characterized in that, A cylindrical body (107) is fixed to the inner wall of the storage groove (103), and a column (108) is slidably connected inside the cylindrical body (107). One end of the column (108) away from the cylindrical body (107) is fixed to a second rubber arc-shaped clamp (105).

6. The autologous immune cell sorting kit according to claim 5, characterized in that, The cylinder (107) has multiple guide grooves (109) inside, and the column (108) has multiple guide rods (110) fixed on the outside. The guide rods (110) slide in the corresponding guide grooves (109).

7. The autologous immune cell sorting kit according to claim 6, characterized in that, A first spring (111) is provided inside the cylinder (107). One end of the first spring (111) abuts against the column (108), and the other end of the first spring (111) abuts against the inner wall of the storage groove (103).

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