Joint inspection device

Abstract

According to the joint detection device, a suction and spitting assembly is used for sucking liquid or spitting liquid so as to collect or separate samples, a reaction tank assembly comprises at least one reaction tank unit, the suction and spitting assembly is used for separating the collected samples to the reaction tank unit so as to prepare sample liquid, a main detection assembly is connected with the reaction tank assembly, and the main detection assembly is connected with the reaction tank assembly. The main detection assembly is used for performing main item detection on the sample liquid, and the sub-detection module is connected with a reaction tank assembly of the main detection module through a liquid path pipeline, so that a sub-item reagent provided by the sub-reagent supply assembly is conveyed to the reaction tank assembly through the sub-power assembly, and the prepared sample liquid is conveyed to the sub-detection assembly; the sub-detection assembly is used for performing sub-item detection on the sample liquid. Based on the mode, the combined detection operation of saccharification detection and blood routine examination can be realized.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of in vitro diagnosis sample detection, in particular to a combined detection device. BACKGROUND

[0002] In the prior art, different types of sample detection are usually configured with corresponding types of sample detection devices, such as blood routine detection devices dedicated to blood routine detection of samples, or glycosylation detection devices dedicated to glycosylation detection of samples.

[0003] The defect of the prior art is that the blood routine detection device cannot perform combined detection of glycosylation detection and blood routine detection, and the glycosylation detection device cannot perform combined detection of glycosylation detection and blood routine detection, that is, the current sample detection device can only perform detection of the type it can perform, and cannot realize combined detection of glycosylation detection and blood routine detection. CONTENT OF THE INVENTION

[0004] The technical problem solved by the present application is how to realize combined detection of glycosylation detection and blood routine detection.

[0005] To solve the above technical problem, the first technical solution adopted by the present application is a combined detection device, comprising: a main detection module comprising suction and discharge assemblies, reaction pool assemblies, and a main detection assembly arranged at intervals; a sub-detection module comprising a sub-reagent supply assembly, a sub-power assembly, and a sub-detection assembly arranged at intervals and connected in sequence, the sub-detection module being independent of other assemblies of the combined detection device; the suction and discharge assemblies are used for suction or discharge of liquid to collect or separate samples; the reaction pool assemblies comprise at least one reaction pool unit, the suction and discharge assemblies are used to separate the collected samples to the reaction pool units to prepare sample liquid; the main detection assembly is connected to the reaction pool assemblies, and the main detection assembly is used to detect the main project of the sample liquid; the sub-detection module is connected to the reaction pool assemblies of the main detection module through a liquid path pipeline, so as to transport the sub-project reagent provided by the sub-reagent supply assembly to the reaction pool assemblies through the sub-power assembly, and transport the prepared sample liquid to the sub-detection assembly; the sub-detection assembly is used to detect the sub-project of the sample liquid.

[0006] The combined detection device further comprises a common control assembly; the main detection module comprises a blood routine detection module, and the sub-detection module comprises a glycosylation detection module; the common control assembly is connected to units in the suction and discharge assemblies, units in the reaction pool assemblies, units in the blood routine detection module, and the sub-power assembly and the sub-detection assembly in the glycosylation detection module.

[0007] The joint inspection device further comprises a main control assembly and a sub-control assembly; the main detection module comprises a routine blood detection module, and the sub-detection module comprises a glycation detection module; the sub-control assembly is connected with the sub-power assembly and the sub-detection assembly in the glycation detection module respectively, and the main control assembly is connected with the unit in the suction and discharge assembly, the unit in the reaction pool assembly, the unit in the routine blood detection module and the sub-control assembly respectively.

[0008] The number of liquid path circuits connected between the glycation detection module and other modules in the joint inspection device is less than or equal to 2, and the number of circuit lines connected between the glycation detection module and other modules in the joint inspection device is less than or equal to 3.

[0009] The liquid path circuits connected between the glycation detection module and other modules in the joint inspection device include a sample liquid conveying path and a waste liquid conveying path, and the circuit lines connected between the glycation detection module and other modules in the joint inspection device include a power supply line, a network port line and a serial port line for connecting other modules.

[0010] The joint inspection device further comprises a power supply assembly; the power supply assembly is connected with the main control assembly and the sub-control assembly respectively, and is used for supplying power for the main control assembly and the sub-control assembly; the main control assembly is used for stopping the glycation detection module from working to shield the glycation detection module.

[0011] The main detection module comprises a routine blood detection module, and the sub-detection module comprises a glycation detection module; the at least one reaction pool unit comprises a common reaction pool unit; the common reaction pool unit is connected with the routine blood detection module and the glycation detection module respectively, and is used for preparing sample liquid corresponding to the routine blood detection and preparing sample liquid corresponding to the glycation detection.

[0012] The main detection module comprises a routine blood detection module, and the sub-detection module comprises a glycation detection module; the at least one reaction pool unit comprises a routine blood reaction pool unit and a glycation reaction pool unit; the routine blood reaction pool unit is connected with the routine blood detection module, and the glycation reaction pool unit is connected with the glycation detection module; the routine blood reaction pool unit is used for preparing sample liquid corresponding to the routine blood detection, and the glycation reaction pool unit is used for preparing sample liquid corresponding to the glycation detection.

[0013] The suction and discharge assembly comprises a pipette needle, a three-way valve, a first liquid driving unit, a first storage unit, a second liquid driving unit and a second storage unit; the liquid stored in the first storage unit is different from the liquid stored in the second storage unit; the pipette needle is connected with a common port of the three-way valve, a first branch port of the three-way valve is connected with a first end of the first liquid driving unit, a second end of the first liquid driving unit is connected with the first storage unit, a second branch port of the three-way valve is connected with a first end of the second liquid driving unit, and a second end of the second liquid driving unit is connected with the second storage unit.

[0014] To solve the above technical problems, the second technical solution adopted by the present application is: a joint inspection device, comprising: a routine blood test module, including a suction and spitting assembly, a reaction pool assembly, and a routine blood test assembly arranged at intervals; a glycation test module, including a glycation reagent supply assembly, a glycation power assembly, and a glycation test assembly arranged at intervals and connected in sequence; the suction and spitting assembly is used for liquid suction or spitting to collect or separate samples; the reaction pool assembly includes at least one reaction pool unit, the suction and spitting assembly is used to separate the collected sample to the reaction pool unit to prepare sample liquid; the routine blood test assembly is connected to the reaction pool assembly, and the routine blood test assembly is used for routine blood test of the sample liquid; the glycation test module is connected to the reaction pool assembly of the routine blood test module through a liquid path pipeline, and the glycation test assembly is used for glycation test of the sample liquid.

[0015] The beneficial effects of the present application are: different from the prior art, in the technical solution of the present application, the suction and spitting assembly is used for liquid suction or spitting to collect or separate samples, the reaction pool assembly includes at least one reaction pool unit, the suction and spitting assembly is used to separate the collected sample to the reaction pool unit to prepare sample liquid, the main detection assembly is connected to the reaction pool assembly, and the main detection assembly is used for main item detection of the sample liquid, the sub-detection module is connected to the reaction pool assembly of the main detection module through a liquid path pipeline, so as to transport the sub-item reagent provided by the sub-reagent supply assembly to the reaction pool assembly through the sub-power assembly, and transport the prepared sample liquid to the sub-detection assembly, and the sub-detection assembly is used for sub-item detection of the sample liquid. Based on the above-mentioned mode, the main detection module and the sub-detection module can be arranged in the joint inspection device, the suction and spitting assembly separates the collected sample to the corresponding reaction pool unit in the reaction pool assembly, thereafter, the sample liquid required by the main detection assembly can be prepared in the reaction pool assembly for main item detection by the main detection assembly, and the sub-item reagent can be transported to the reaction pool assembly by the reagent supply assembly to prepare the sample liquid required by the sub-detection assembly for sub-item detection by the main detection assembly. In practice, the main item detection can be routine blood test, and the sub-item detection can be glycation test, so as to realize joint inspection operation of glycation test and routine blood test in the same device. BRIEF DESCRIPTION OF DRAWINGS

[0016] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings needed in the embodiment description will be briefly introduced as follows. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can also be obtained by those skilled in the art without creative labor.

[0017] Figure 1 is a structural schematic diagram of an embodiment of the joint inspection device of the present application;

[0018] Figure 2 is a structural schematic diagram of an embodiment of the joint inspection device of the present application;

[0019] Figure 3 is a structural schematic diagram of an embodiment of the joint inspection device of the present application;

[0020] Figure 4 is a structural schematic diagram of an embodiment of the joint inspection device of the present application;

[0021] Figure 5 is a structural schematic diagram of an embodiment of the suction and discharge assembly and the reaction cell assembly of the present application.

[0022] The reference signs are as follows: 1, main detection module; 11, suction and discharge assembly; 111, pipette; 112, three-way valve; 113, first liquid driving unit; 114, first storage unit; 115, second liquid driving unit; 116, second storage unit; 12, reaction cell assembly; 13, main detection assembly; 2, sub detection module; 21, sub reagent supply assembly; 22, sub power assembly; 23, sub detection assembly; 3, liquid path support assembly; 4, common control assembly; 5, main control assembly; 6, sub control assembly. DETAILED DESCRIPTION

[0023] The technical solutions in the embodiments of the present application will be described clearly and completely below with reference to the drawings in the embodiments of the present application. It can be understood that the specific embodiments described herein are only used to explain the present application, but not to limit the present application. In addition, it should be noted that, for the convenience of description, only the parts related to the present application are shown in the drawings, but not all the structures. Based on the embodiments in the present application, all the other embodiments obtained by those skilled in the art without creative labor fall within the scope of the present application.

[0024] The terms "first", "second", "third", etc. in the present application are only for descriptive purpose, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of the technical features indicated. Therefore, the features defined with "first", "second", "third" can explicitly or implicitly include at least one of the features. In the description of the present application, the meaning of "multiple" is at least two, such as two, three, etc., unless otherwise explicitly specified. All directional indications (such as up, down, left, right, front, back, etc.) in the embodiments of the present application are only used to explain the relative position relationship, movement condition, etc. between components in a certain posture (as shown in the drawings), and if the certain posture changes, the directional indications also change accordingly. In addition, the terms "include" and "have" and any variations thereof are intended to cover non-exclusive inclusion. For example, a process, method, system, product or device including a series of steps or units is not limited to the listed steps or units, but can optionally include steps or units not listed, or can optionally include other steps or units inherent to the process, method, product or device.

[0025] Reference to "embodiments" herein means that the specific features, structures or characteristics described in connection with the embodiments can be included in at least one embodiment of the present application. The phrase appears at various places in the specification does not necessarily all refer to the same embodiments, nor is it necessarily independent or alternative embodiments to other embodiments. It is explicitly and implicitly understood by those skilled in the art that the embodiments described herein can be combined with other embodiments.

[0026] The present application proposes a joint detection device, referring to Figures 1 to 4 , Figure 1 is one of the structural schematic diagrams of an embodiment of the joint detection device of the present application, Figure 2 is another structural schematic diagram of an embodiment of the joint detection device of the present application, Figure 3 is a third structural schematic diagram of an embodiment of the joint detection device of the present application, Figure 4 is a fourth structural schematic diagram of an embodiment of the joint detection device of the present application, as Figures 1 to 4 shown, the joint detection device includes a main detection module 1 and a sub-detection module 2.

[0027] The main detection module 1 includes a suction and discharge assembly 11, a reaction pool assembly 12, and a main detection assembly 13 arranged at intervals.

[0028] The sub-detection module 2 includes a sub-reagent supply assembly 21, a sub-power assembly 22, and a sub-detection assembly 23 arranged at intervals and connected in sequence, and the sub-detection module 2 is arranged independently of other assemblies of the joint detection device.

[0029] It should be noted that, as Figure 2 and Figure 3As shown, the joint detection device can also be provided with a liquid path support assembly 3, which can be used to transport liquid between any two components in the main detection module 1 and the sub-detection module 2. In an example, the main detection module 1 can include a routine blood detection module, and the sub-detection module 2 can include a glycosylation detection module. The joint detection device can also integrate a blood sedimentation detection module, a specific protein detection module, and other types of detection devices. Alternatively, the main detection module 1 can be any type of detection module, and the sub-detection module 2 can be any other type of detection module, to achieve the integration of more types of detection devices and perform more types of joint detection operations. Here, no limitation is made.

[0030] The suction and discharge assembly 11 is used for suction or discharge of liquid to collect or separate samples. Specifically, the suction and discharge assembly 11 can have a pipette and a corresponding liquid driving unit connected thereto. The liquid driving unit can provide positive pressure or negative pressure to the pipette. When the opening of the pipette is in the sample, the suction force can be provided to perform suction to collect the sample. When the opening of the pipette is on the corresponding container, the discharge can be performed to separate the sample.

[0031] The reaction cell assembly 12 includes at least one reaction cell unit. The suction and discharge assembly 11 is used to separate the collected sample to the reaction cell unit to prepare sample liquid. Specifically, at least one reaction cell unit can be provided in the reaction cell assembly 12. Each reaction cell unit can be understood as a reaction cell for preparing sample liquid. After the sample collected by the suction and discharge assembly 11 is separated into the corresponding reaction cell unit, the corresponding reagent can be added to prepare the corresponding sample liquid for sample detection. For example, the sample and the diluent can be mixed to obtain the sample liquid required for routine blood detection. The sample and the hemolytic agent can be mixed to obtain the sample liquid required for glycosylation detection. The sample and other types of reagents can be mixed to obtain the sample liquid for corresponding applications. Here, no limitation is made.

[0032] The main detection assembly 13 is connected to the reaction cell assembly 12, and is used to perform main item detection on the sample liquid. Specifically, when the main detection module 1 includes a routine blood detection module, the routine blood detection module is connected to the reaction cell assembly 12. The main detection assembly 13 belonging to the routine blood detection module can be used to perform routine blood detection. The routine blood detection module can be used to perform routine blood detection on the sample liquid to obtain routine blood detection results. The routine blood detection can generally include red blood cell count (RBC), hemoglobin (Hb), white blood cell (WBC), white blood cell differential count, and platelet (PLT) detection. Other types of routine blood detection items can also be included. Here, no limitation is made.

[0033] The sub-detection module 2 is connected with the reaction pool assembly 12 of the main detection module 1 through a liquid channel, so as to transport the sub-project reagent provided by the sub-reagent supply assembly 21 to the reaction pool assembly 12 through the sub-power assembly 22, and transport the prepared sample liquid to the sub-detection assembly 23. The sub-detection assembly 23 is used for sub-project detection of the sample liquid. For example, when the sub-detection module 2 includes a glycosylation detection module, the glycosylation detection module is connected with the reaction pool assembly 12, and the sub-detection assembly 23 belonging to the glycosylation detection module can be used for glycosylation detection. The sub-detection assembly 23 belonging to the glycosylation detection module can include an elution assembly and a detection assembly, the elution assembly includes a high-pressure pump, a six-way valve and a chromatographic column connected with each other, and the elution assembly is used for gradient elution of the prepared corresponding sample liquid to realize component separation; the detection assembly detects the sample liquid after component separation to obtain the detection result of glycosylation detection.

[0034] For example, it is assumed that the main detection module 1 includes a blood routine detection module, and the sub-detection module 2 includes a glycosylation detection module. The sample can be collected by controlling the suction and discharge assembly 11, and then the sample for blood routine detection is separated by controlling the suction and discharge assembly 11 in sequence, and the sample for glycosylation detection is separated by controlling the suction and discharge assembly 11. In the reaction pool assembly 12, if the sample for blood routine detection is separated first, and then the sample for glycosylation detection is separated, the suction and discharge assembly 11 can be cleaned with a hemolytic agent after the sample for blood routine detection is separated, and before the sample for glycosylation detection is separated, so as to reduce the possibility that the hemolytic agent in the sample liquid for glycosylation detection has a negative impact on blood routine detection. Similarly, if the sample for glycosylation detection is separated first, and then the sample for blood routine detection is separated, the suction and discharge assembly 11 can be cleaned with a diluent after the sample for glycosylation detection is separated, and before the sample for blood routine detection is separated, so as to reduce the possibility that the diluent in the sample liquid for blood routine detection has a negative impact on glycosylation detection, thereby reducing the possibility of cross contamination between glycosylation detection and blood routine detection.

[0035] Based on the above mode, the combined detection operation of glycosylation detection and blood routine detection can be realized in the combined detection device, or the combined detection operation of any other two different types of detection can be realized, which is not limited here. By independently and centrally arranging the components included in the sub-detection module 2, the sub-detection module 2 can be easily disassembled and maintained, and the function of the sub-detection module 2 can be configured or directly shielded as needed in actual use scenarios, without affecting the use of the main detection module 1 or the consumption of reagents and power caused by maintaining the sub-detection module 2.

[0036] Based on this, the overall efficiency of sample detection can be improved, and the consistency of samples used for glycation detection and blood routine detection can be improved by reducing the time for sample liquid preparation or transportation between different types of sample detection devices, or the consistency of samples used for any other two different types of detection can be improved, thereby improving the accuracy of sample detection.

[0037] Unlike the prior art, in the technical solution of the present application, the suction and discharge assembly 11 is used to suck or discharge liquid to collect or sub-sample the sample, the reaction pool assembly 12 includes at least one reaction pool unit, the suction and discharge assembly 11 is used to sub-sample the collected sample to the reaction pool unit to prepare the sample liquid, the main detection assembly 13 is connected to the reaction pool assembly 12, and the main detection assembly 13 is used to detect the main project of the sample liquid. The sub-detection module 2 is connected to the reaction pool assembly 12 of the main detection module 1 through a liquid path, so as to transport the sub-project reagent provided by the sub-reagent supply assembly 21 to the reaction pool assembly 12 through the sub-power assembly 22, and transport the prepared sample liquid to the sub-detection assembly 23, and the sub-detection assembly 23 is used to detect the sub-project of the sample liquid. Based on the above-mentioned manner, the main detection module 1 and the sub-detection module 2 can be provided in the combined detection device, the suction and discharge assembly 11 sub-samples the collected sample to the corresponding reaction pool unit in the reaction pool assembly 12, thereafter, the sample liquid required by the main detection assembly 13 can be prepared in the reaction pool assembly 12 for the main project detection of the main detection assembly 13, or the sub-project reagent can be transported to the reaction pool assembly 12 by the reagent supply assembly to prepare the sample liquid required by the sub-detection assembly 23 for the sub-project detection of the main detection assembly 13. In practice, the main project detection can be blood routine detection, and the sub-project detection can be glycation detection, so as to realize the combined detection operation of glycation detection and blood routine detection in the same device.

[0038] In an embodiment, as shown in Figure 1 and Figure 3 The main detection module 1 includes a blood routine detection module, and the sub-detection module 2 includes a glycation detection module, and the at least one reaction pool unit includes a common reaction pool unit.

[0039] The common reaction pool unit is connected to the blood routine detection module and the glycation detection module respectively, and is used to prepare the sample liquid corresponding to the blood routine detection and to prepare the sample liquid corresponding to the glycation detection.

[0040] Specifically, the main detection module 1 can include a blood routine detection module, the blood routine detection module can include the suction and discharge assembly 11, the reaction pool assembly 12, and the main detection assembly 13, the sub-detection module 2 can include a glycation detection module, the glycation detection module can include the sub-reagent supply assembly 21, the sub-power assembly 22, and the sub-detection assembly 23, the main detection assembly 13 can be used for blood routine detection, and the sub-detection assembly 23 can be used for glycation detection.

[0041] The pipetting component 11 can sequentially perform the sample separation operation of the sample liquid corresponding to the routine blood test and the sample separation operation of the sample liquid corresponding to the glycation test in the common reaction cell unit, and perform the preparation operation of the sample liquid corresponding to the routine blood test and the preparation operation of the sample liquid corresponding to the glycation test after the corresponding sample separation operation, respectively. The sequence of the two sample separation operations can be any sequence, which is not limited here.

[0042] For example, the sample separation operation and the preparation operation of the sample liquid corresponding to the routine blood test can be performed in the common reaction cell unit first, then the pipetting component 11 and the common reaction cell unit are cleaned, and then the sample separation operation and the preparation operation of the sample liquid corresponding to the glycation test are performed in the common reaction cell unit. Alternatively, the sample separation operation and the preparation operation of the sample liquid corresponding to the glycation test can be performed in the common reaction cell unit first, then the pipetting component 11 and the common reaction cell unit are cleaned, and then the sample separation operation and the preparation operation of the sample liquid corresponding to the routine blood test are performed in the common reaction cell unit.

[0043] Based on the above manner, the preparation of the sample liquid corresponding to the routine blood test and the sample liquid corresponding to the glycation test can be realized in the same reaction cell unit, the space volume required by the reaction cell assembly 12 is reduced, and the integration of the combined testing device is improved.

[0044] In an embodiment, as shown in Figure 2 and Figure 4 The main testing module 1 includes a routine blood test module, the sub-testing module 2 includes a glycation test module, and the at least one reaction cell unit includes a routine blood test reaction cell unit and a glycation test reaction cell unit.

[0045] The routine blood test reaction cell unit is connected to the routine blood test module, and the glycation test reaction cell unit is connected to the glycation test module. The routine blood test reaction cell unit is used to prepare the sample liquid corresponding to the routine blood test, and the glycation test reaction cell unit is used to prepare the sample liquid corresponding to the glycation test.

[0046] Specifically, the main testing module 1 can include a routine blood test module, the routine blood test module can include the pipetting component 11, the reaction cell assembly 12, and the main testing assembly 13, the sub-testing module 2 can include a glycation test module, the glycation test module can include the sub-reagent supply assembly 21, the sub-power assembly 22, and the sub-testing assembly 23, the main testing assembly 13 can be used to perform the routine blood test, and the sub-testing assembly 23 can be used to perform the glycation test.

[0047] The controllable suction and spitting assembly 11 performs sample dispensing of sample liquid corresponding to blood routine test in the blood routine reaction cell unit and sample dispensing of sample liquid corresponding to glycation test in the glycation reaction cell unit in sequence, and performs preparation of sample liquid corresponding to blood routine test and preparation of sample liquid corresponding to glycation test after the respective sample dispensing. The sequence of the two sample dispensing can be any sequence, and the preparation time of the two preparations can have no overlapping time or at least partial overlapping time, which is not limited here.

[0048] For example, the sample dispensing and preparation of sample liquid corresponding to blood routine test can be performed in the blood routine reaction cell unit first, then the controllable suction and spitting assembly 11 and the blood routine reaction cell unit are cleaned, and then the sample dispensing and preparation of sample liquid corresponding to glycation test are performed in the glycation reaction cell unit, or the sample dispensing and preparation of sample liquid corresponding to glycation test can be performed in the glycation reaction cell unit first, then the controllable suction and spitting assembly 11 and the glycation reaction cell unit are cleaned, and then the sample dispensing and preparation of sample liquid corresponding to blood routine test are performed in the blood routine reaction cell unit.

[0049] Based on the above mode, the preparation of sample liquid corresponding to blood routine test and sample liquid corresponding to glycation test can be realized in different reaction cell units, further reducing the possibility of cross contamination of blood routine test and glycation test, and improving the accuracy of sample detection.

[0050] In an embodiment, as shown in Figure 1 and Figure 2 The combined detection device further comprises a common control assembly 4. The main detection module 1 comprises a blood routine test module, and the sub detection module 2 comprises a glycation test module.

[0051] The common control assembly 4 is connected with units in the controllable suction and spitting assembly 11, units in the reaction cell assembly 12, units in the blood routine test module, and sub power assembly 22 and sub detection assembly 23 in the glycation test module, respectively.

[0052] Specifically, the main detection module 1 can comprise a blood routine test module, the blood routine test module can comprise the controllable suction and spitting assembly 11, the reaction cell assembly 12, and the main detection assembly 13, the sub detection module 2 can comprise a glycation test module, the glycation test module can comprise the sub reagent supply assembly 21, the sub power assembly 22, and the sub detection assembly 23, the main detection assembly 13 can be used for blood routine test, and the sub detection assembly 23 can be used for glycation test.

[0053] One common control assembly 4 can be used to control each module or assembly or unit in the combined detection device, so that the structure of the combined detection device is relatively low in complexity, low in construction cost, and convenient to maintain.

[0054] In an embodiment, as shown in Figure 3 and Figure 4 The combined detection device further comprises a main control assembly 5 and a sub-control assembly 6. The main detection module 1 comprises a routine blood detection module, and the sub-detection module 2 comprises a glycosylation detection module.

[0055] The sub-control assembly 6 is connected with the sub-power assembly 22 and the sub-detection assembly 23 in the glycosylation detection module respectively, and the main control assembly 5 is connected with the unit in the suction and discharge assembly 11, the unit in the reaction pool assembly 12, the unit in the routine blood detection module, and the sub-control assembly 6 respectively.

[0056] Specifically, the main detection module 1 can comprise a routine blood detection module, the routine blood detection module can comprise the suction and discharge assembly 11, the reaction pool assembly 12, and the main detection assembly 13, the sub-detection module 2 can comprise a glycosylation detection module, the glycosylation detection module can comprise the sub-reagent supply assembly 21, the sub-power assembly 22, and the sub-detection assembly 23, the main detection assembly 13 can be used for routine blood detection, and the sub-detection assembly 23 can be used for glycosylation detection.

[0057] A sub-control assembly 6 for controlling the glycosylation detection module can be provided, and a main control assembly 5 for controlling the unit in the suction and discharge assembly 11, the unit in the reaction pool assembly 12, the unit in the routine blood detection module, and the sub-control assembly 6 respectively can be provided. If the glycosylation detection function of the glycosylation detection module needs to be shielded, the main control assembly 5 can be used to control the glycosylation detection module to stop working at the software level based on the sub-control assembly 6, so as to shield the glycosylation detection function. For example, a function of timing shielding can be set to put the glycosylation detection module into hibernation or power-off, or the user can be prompted to maintain and clean the glycosylation detection module after a preset operation time, or the glycosylation detection module can be automatically powered off after the process ends or within a preset time after the process ends if the user does not respond. Based on the above-mentioned manner, the main control assembly 5 and the sub-control assembly 6 can be set in such a way that the glycosylation detection module is more convenient, the problem diagnosis is simpler, and the user operation is more flexible.

[0058] In an example, the glycosylation detection module and the sub-control assembly 6 can be an independently operable device for performing glycosylation detection independently. When glycosylation detection is not needed, the glycosylation detection module and the sub-control assembly 6 can be taken out separately from other modules in the combined detection device. The glycosylation detection device composed of the glycosylation detection module and the sub-control assembly 6 is more independent, and has higher flexibility in use.

[0059] Optionally, the number of liquid paths connected between the glycosylation detection module and other modules in the combined detection device is less than or equal to 2, and / or the number of circuit lines connected between the glycosylation detection module and other modules in the combined detection device is less than or equal to 3.

[0060] Specifically, the liquid channel pipes connected between the glycation detection module and other modules or components or units in the joint detection device respectively include a sample liquid conveying pipe and a waste liquid conveying pipe. The sample liquid conveying pipe can be specifically a pipe for conveying sample liquid between the glycation detection module and the reaction pool component 12, and the waste liquid conveying pipe can be specifically a pipe for conveying waste liquid between the glycation detection module and the reaction pool component 12, and the waste liquid in the joint detection device can be conveyed to the reaction pool component 12 and then discharged. The circuit lines connected between the glycation detection module and other modules or components or units in the joint detection device respectively include a power supply line, a network port line and a serial port line for connecting other modules. According to actual needs, the network port line and the serial port line can be replaced by other types of lines, or other types of lines can be added, which are not limited here.

[0061] Optionally, the joint detection device further comprises a power supply component.

[0062] The power supply component is connected with the main control component 5 and the sub-control component 6 respectively, and is used for supplying power to the main control component 5 and the sub-control component 6.

[0063] The main control component 5 is used for stopping the operation of the glycation detection module to shield the glycation detection module.

[0064] Specifically, if it is necessary to shield the glycation detection function of the glycation detection module, in addition to the method of controlling the sub-control component 6 to stop the operation of the glycation detection module through the main control component 5 at the software level as mentioned in the foregoing embodiments, the power supply component can also be controlled to stop supplying power to the sub-control component 6 and / or the glycation detection module based on the main control component 5 at the hardware level, so as to realize shielding of the glycation detection function at the software level and / or the hardware level.

[0065] Based on the above method, more methods can be used to control the start of the glycation detection module, thereby improving the use flexibility and reliability of the joint detection device.

[0066] In an embodiment, referring to Figure 5 , Figure 5 is a structural schematic diagram of an embodiment of the suction and discharge component and the reaction pool component, as Figure 5 shown, the suction and discharge component 11 further comprises a pipette needle 111, a three-way valve 112, a first liquid driving unit 113, a first storage unit 114, a second liquid driving unit 115 and a second storage unit 116, and the liquid stored in the first storage unit 114 and the liquid stored in the second storage unit 116 are different.

[0067] The pipetting needle 111 is connected to a common port of the three-way valve 112, a first branch port of the three-way valve 112 is connected to a first end of the first liquid driving unit 113, a second end of the first liquid driving unit 113 is connected to the first storage unit 114, a second branch port of the three-way valve 112 is connected to a first end of the second liquid driving unit 115, and a second end of the second liquid driving unit 115 is connected to the second storage unit 116.

[0068] Specifically, for example, the liquid stored in the first storage unit 114 can be a hemolytic agent, and the liquid stored in the second storage unit 116 can be a diluent. After the sample is split in the reaction pool assembly 12, if the sample liquid required for the preparation of the glycosylated detection is needed in the reaction pool assembly 12, the first liquid driving unit 113 can be controlled to suck the hemolytic agent and spit the hemolytic agent into the reaction pool assembly 12 for preparation of the sample liquid. If the sample liquid required for the preparation of the blood routine detection is needed in the reaction pool assembly 12, the second liquid driving unit 115 can be controlled to suck the diluent and spit the diluent into the reaction pool assembly 12 for preparation of the sample liquid.

[0069] Based on the above mode, the suction and spitting assembly 11 can have the ability to add different types of sample liquids required for detection, thereby improving the multiplicity of the suction and spitting assembly 11, and further improving the integration of the combined detection device.

[0070] The application also provides a combined detection device, as shown in Figures 1 to 4 The combined detection device includes a main detection module 1 and a sub-detection module 2.

[0071] The main detection module 1 can be a blood routine detection module, and the sub-detection module 2 can be a glycosylated detection module.

[0072] The blood routine detection module includes a suction and spitting assembly 11, a reaction pool assembly 12, and a main detection assembly 13.

[0073] The glycosylated detection module includes a sub-reagent supply assembly 21, a sub-power assembly 22, and a sub-detection assembly 23 which are sequentially connected and arranged at intervals. The sub-detection module 2 is independent of other assemblies of the combined detection device.

[0074] The suction and spitting assembly 11 is used for liquid suction or liquid spitting to collect or split the sample.

[0075] The reaction pool assembly 12 includes at least one reaction pool unit, and the suction and spitting assembly 11 is used to split the collected sample to the reaction pool unit for preparation of the sample liquid.

[0076] The blood routine detection assembly is connected to the reaction pool assembly 12, and the blood routine detection assembly is used for blood routine detection of the sample liquid.

[0077] The glycosylation detection module is connected with the reaction pool assembly 12 of the blood routine detection module through a liquid path pipeline, so as to transport the sub-project reagent provided by the sub-reagent supply assembly 21 to the reaction pool assembly 12 through the sub-power assembly 22, and transport the prepared sample liquid to the sub-detection assembly 23. The sub-detection assembly 23 is used for glycosylation detection of the sample liquid.

[0078] In the technical solution of the present application, the suction and discharge assembly is used for suction or discharge of liquid to collect or sub-sample the sample, the reaction pool assembly includes at least one reaction pool unit, the suction and discharge assembly is used for sub-sampling the collected sample to the reaction pool unit to prepare the sample liquid, the main detection assembly is connected with the reaction pool assembly, the main detection assembly is used for main project detection of the sample liquid, the sub-detection module is connected with the reaction pool assembly of the main detection module through a liquid path pipeline, so as to transport the sub-project reagent provided by the sub-reagent supply assembly to the reaction pool assembly through the sub-power assembly, and transport the prepared sample liquid to the sub-detection assembly, and the sub-detection assembly is used for sub-project detection of the sample liquid. Based on the above-mentioned mode, the main detection module and the sub-detection module can be arranged in the combined detection device, the suction and discharge assembly sub-samples the collected sample to the corresponding reaction pool unit in the reaction pool assembly, thereafter, the sample liquid required by the main detection assembly can be prepared in the reaction pool assembly for main project detection of the main detection assembly, and the sub-project reagent can be transported to the reaction pool assembly by the reagent supply assembly to prepare the sample liquid required by the sub-detection assembly for sub-project detection of the main detection assembly. In practice, the main project detection can be blood routine detection, and the sub-project detection can be glycosylation detection, so that the combined detection operation of glycosylation detection and blood routine detection in the same device is realized.

[0079] The above-mentioned is only the embodiment of the present application, and does not limit the patent scope of the present application, and any equivalent structure or equivalent flow transformation based on the content of the specification and the drawings, or direct or indirect application in other related technical fields, are also included in the patent protection scope of the present application.

Claims

1. A joint inspection device, characterized in that, include: The main detection module includes a suction and discharge assembly, a reaction chamber assembly, and a main detection assembly arranged at intervals. The sub-detection module includes a sub-reagent supply component, a sub-power component, and a sub-detection component that are spaced apart and connected in sequence. The sub-detection module is set independently of the other components of the joint detection device. The aspiration and expulsion assembly is used for aspiration or expulsion of liquid to collect or separate samples. The reaction chamber assembly includes at least one reaction chamber unit, and the aspiration and dispensing assembly is used to dispense the collected sample into the reaction chamber unit for sample solution preparation. The main detection component is connected to the reaction cell component, and the main detection component is used to perform main item detection on the sample solution. The sub-detection module is connected to the reaction cell assembly of the main detection module via a liquid pipeline, so that the sub-reagent supply assembly provides the sub-item reagents to the reaction cell assembly through the sub-power assembly, and the prepared sample solution is delivered to the sub-detection assembly; the sub-detection assembly is used to perform sub-item detection on the sample solution.

2. The joint inspection device according to claim 1, characterized in that, The joint testing device also includes a common control component; the main testing module includes a routine blood test module, and the sub-testing module includes a glycated blood glucose test module; The common control component is connected to the unit in the aspiration and expulsion component, the unit in the reaction tank component, the unit in the blood routine detection module, and the sub-power component and the sub-detection component in the glycation detection module.

3. The joint inspection device according to claim 1, characterized in that, The joint detection device also includes a main control component and a sub-control component; the main detection module includes a blood routine detection module, and the sub-detection module includes a glycated blood glucose detection module; The sub-control components are respectively connected to the sub-power component and the sub-detection component in the glycation detection module, and the main control component is respectively connected to the unit in the aspiration and expulsion component, the unit in the reaction cell component, the unit in the blood routine detection module, and the sub-control components.

4. The joint inspection device according to claim 3, characterized in that, The number of liquid pipelines connecting the saccharification detection module to other modules in the joint inspection device is less than or equal to 2, and the number of electrical circuits connecting the saccharification detection module to other modules in the joint inspection device is less than or equal to 3.

5. The joint inspection device according to claim 4, characterized in that, The liquid pipelines connecting the saccharification detection module to other modules in the joint testing device include sample liquid delivery pipelines and waste liquid delivery pipelines. The circuit lines connecting the saccharification detection module to other modules in the joint testing device include power lines, network port lines, and serial port lines for connecting other modules.

6. The joint inspection device according to claim 3, characterized in that, The joint inspection device also includes a power supply assembly; The power supply component is connected to the main control component and the sub-control component respectively, and the power supply component is used to supply power to the main control component and the sub-control component; The main control component is used to disable the saccharification detection module by controlling it to stop operating.

7. The joint inspection device according to claim 1, characterized in that, The main detection module includes a routine blood count detection module, the sub-detection module includes a glycation end product (GA) detection module, and the at least one reaction cell unit includes a common reaction cell unit. The common reaction cell unit is connected to the routine blood test module and the glycated blood glucose test module respectively. The common reaction cell unit is used to prepare the sample solution corresponding to the routine blood test and the sample solution corresponding to the glycated blood glucose test.

8. The joint inspection device according to claim 1, characterized in that, The main detection module includes a routine blood count detection module, and the sub-detection module includes a glycation end product (GA) detection module; the at least one reaction chamber unit includes a routine blood count reaction chamber unit and a GA reaction chamber unit. The routine blood test reaction unit is connected to the routine blood test module, and the glycated blood glucose reaction unit is connected to the glycated blood glucose test module. The routine blood test reaction unit is used to prepare the sample solution corresponding to the routine blood test, and the glycated blood glucose reaction unit is used to prepare the sample solution corresponding to the glycated blood glucose test.

9. The joint inspection device according to claim 1, characterized in that, The aspiration and dispensing assembly includes a pipette, a three-way valve, a first liquid dispensing unit, a first storage unit, a second liquid dispensing unit, and a second storage unit. The liquid stored in the first storage unit is different from the liquid stored in the second storage unit. The pipette is connected to the common port of the three-way valve. The first branch port of the three-way valve is connected to the first end of the first liquid-driving unit. The second end of the first liquid-driving unit is connected to the first storage unit. The second branch port of the three-way valve is connected to the first end of the second liquid-driving unit. The second end of the second liquid-driving unit is connected to the second storage unit.

10. A joint inspection device, characterized in that, include: The blood routine test module includes an aspiration and expulsion assembly, a reaction chamber assembly, and a blood routine test assembly arranged at intervals; The saccharification detection module includes a saccharification reagent supply component, a saccharification power component, and a saccharification detection component that are spaced apart and connected in sequence; The aspiration and expulsion assembly is used for aspiration or expulsion of liquid to collect or separate samples. The reaction chamber assembly includes at least one reaction chamber unit, and the aspiration and dispensing assembly is used to dispense the collected sample into the reaction chamber unit for sample solution preparation. The routine blood test component is connected to the reaction cell component, and the routine blood test component is used to perform routine blood tests on the sample solution; The glycation detection module is connected to the reaction cell assembly of the blood routine detection module via a liquid pipeline, and the glycation detection assembly is used to perform glycation detection on the sample solution.

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