Liquid absorption device and automatic chemiluminescence analysis equipment

Abstract

The utility model discloses a liquid suction device and automatic chemiluminescence analysis equipment. The liquid suction device comprises a mounting frame, a liquid suction pipe and a liquid suction pipe, the linear motor is mounted on the mounting frame; the linear guide rail is fixed on the mounting frame and the guiding direction of the linear guide rail is the same as the driving direction of the linear motor; the sliding seat is driven by the linear motor to do linear motion and is connected to the linear guide rail in a sliding mode in the guiding direction of the linear guide rail; the liquid suction assembly is connected to the sliding seat; the liquid suction assembly is provided with a liquid suction needle which does linear motion synchronously with the sliding base and is used for sucking liquid. The linear motor cancels a mechanical intermediate transmission link from the motor to the liquid suction needle, so that the transmission error and the lag phenomenon are reduced, the response time is greatly shortened, the liquid suction operation can be automatically completed in a shorter time, and the rapid and automatic liquid suction requirement of large-scale high-speed chemiluminescence analysis equipment is met.

Description

TECHNICAL FIELD

[0001] The utility model relates to in-vitro diagnosis analysis equipment technical field, concretely relates to a kind of liquid suction device and automatic chemiluminescence analysis equipment. BACKGROUND

[0002] In the in-vitro diagnosis analysis equipment such as full-automatic chemiluminescence immunoassay instrument, the reactant mixed with to-be-measured sample and reagent is usually placed in reaction cup to carry out mixing, incubation and cleaning separation after step, then signal reagent is added in reaction cup to measure optical signal or electrical signal, so that the measurement and analysis of target analyte contained in to-be-measured sample are realized.

[0003] The existing full-automatic chemiluminescence immunoassay instrument includes rack, photometric disc device, liquid injection mechanism and grabbing mechanism installed above the rack; the photometric disc device is provided with a plurality of circumferentially arranged reaction cups, and the reaction cup is the mixing, reaction and incubation place of to-be-measured sample and reagent; the photometric disc device drives the reaction cup to rotate to realize the mixing of internal reactant. In order to realize the separation of free label and immune complex label in the reaction cup, the unbound component in the reaction cup is usually sucked by using liquid suction needle; the liquid suction needle needs to be able to make lifting motion to suck the liquid in the reaction cup when working.

[0004] In the prior art, the liquid suction device basically adopts the mode of rotary motor + belt transmission to drive the liquid suction needle to make vertical lifting motion; the response speed and liquid suction speed of such liquid suction device are slow, and only the automatic liquid suction demand of full-automatic chemiluminescence immunoassay instrument with small number of reaction cups in photometric disc and slow rotation speed of photometric disc can be met, and it is difficult to meet the high-speed test requirement of to-be-measured sample of high-speed automatic chemiluminescence immunoassay instrument. Therefore, how to overcome the restriction of liquid suction device on the realization of high-speed test of full-automatic chemiluminescence immunoassay instrument is a technical problem to be solved urgently at present. UTILITY MODEL CONTENTS

[0005] Therefore, the utility model provides a kind of liquid suction device and automatic chemiluminescence analysis equipment to solve the technical problem that the response speed and liquid suction speed of existing liquid suction device are slow, and the structure is complex, which restricts the realization of high-speed test of automatic chemiluminescence analysis equipment.

[0006] To solve the above technical problems, the technical scheme of the utility model is as follows:

[0007] A kind of liquid suction device, comprising:

[0008] mounting frame;

[0009] linear motor, installed on the mounting frame;

[0010] linear guide rail, fixed on the mounting frame, and the guide direction thereof is same as the driving direction of the linear motor;

[0011] a sliding seat driven by the linear motor to move linearly and slide along the guiding direction of the linear guide rail;

[0012] a liquid suction assembly connected to the sliding seat, the liquid suction assembly being provided with a liquid suction needle moving linearly synchronously with the sliding seat and used for suction of liquid.

[0013] By using the above technical scheme, in the liquid suction process of the liquid suction device, the linear motor directly drives the sliding seat and the liquid suction assembly to move vertically along the guiding direction of the linear guide rail, and when the liquid suction needle is lowered into the reaction cup, the liquid suction needle can suck the liquid in the reaction cup, thereby realizing automatic liquid suction operation of the chemiluminescence analysis equipment. Compared with the existing rotary motor indirectly driving the liquid suction needle to move vertically through a belt transmission mechanism, since the linear motor cancels the mechanical intermediate transmission link between the motor and the liquid suction needle, transmission error and hysteresis are reduced, the response time of the liquid suction needle moving vertically is greatly shortened, the reaction is sensitive and fast, the liquid suction operation can be automatically completed in a shorter time, the rapid automatic liquid suction requirement of large-scale high-speed chemiluminescence analysis equipment is met, and the problem that the existing liquid suction device restricts the realization of high-speed testing of the full-automatic chemiluminescence analysis equipment due to slow liquid suction response speed, slow liquid suction speed and complex structure is overcome.

[0014] Further, the mounting frame comprises a vertically arranged support plate and a horizontally arranged motor mounting plate; one end of the support plate is fixed on a photodisk device of the chemiluminescence analysis equipment, the motor mounting plate is fixed on the other end of the support plate, and the linear motor is mounted on the side of the motor mounting plate away from the support plate.

[0015] By using the above technical scheme, one end of the support plate is directly fixed on the photodisk device of the chemiluminescence analysis equipment, and the linear motor is mounted on the side of the motor mounting plate away from the support plate, so that the modular design of the liquid suction device and the photodisk device can be realized, the space occupation of the liquid suction device is reduced, and the volume of the entire full-automatic chemiluminescence analysis equipment is further reduced. In addition, the linear motor is mounted on the side of the motor mounting plate away from the support plate, so that the linear motor can be as far away from the photodisk device as possible, and the influence of heat generated by the linear motor on the internal reactants of the photodisk device during operation of the linear motor is avoided.

[0016] Further, the support plate is a plastic part.

[0017] By using the above technical scheme, the support plate is designed as a plastic part, so that the influence of heat generated by the linear motor on the internal reactants of the photodisk device during operation of the linear motor is avoided.

[0018] Further, the support plate is a frame-shaped structure with an internal hollow space, and the sliding seat is located at least partially in the internal hollow space of the support plate.

[0019] By adopting the above technical scheme, the compactness of the liquid suction device can be further improved, and the space occupation of the liquid suction device can be reduced.

[0020] Further, the mounting frame is provided with a position detection sensor, and the sliding seat is connected with a stroke stopper that moves synchronously with the sliding seat; when the position detection sensor detects the stroke stopper signal, the position detection sensor sends an induction signal to the controller to control the linear motor to stop running.

[0021] By adopting the above technical scheme, the position detection sensor and the stroke stopper can limit the movement stroke of the sliding seat and the liquid suction needle.

[0022] Further, the position detection sensor is an optical coupling switch, and the stroke stopper is an optical coupling piece.

[0023] Further, the linear motor is a linear stepping motor.

[0024] By adopting the above technical scheme, the linear stepping motor has the advantages of small size, light weight, short response time, high transmission stiffness, stable thrust, high movement precision, small wear, long service life, and the like, and can be stably operated for a long time.

[0025] Further, the liquid suction assembly further comprises a buffer seat fixed to the sliding seat, a needle sleeve fixed to the outside of the liquid suction needle, and a locking piece for locking the needle sleeve on the buffer seat; the buffer seat is provided with a through hole for the liquid suction needle to pass through.

[0026] By adopting the above technical scheme, the liquid suction needle is installed on the sliding seat through the buffer seat, which can provide certain buffering protection to avoid damage to the liquid suction needle; and the locking piece is arranged to facilitate replacement of the needle sleeve and the liquid suction needle, and different models of liquid suction needles can be selected according to needs.

[0027] An automatic chemiluminescence analysis device comprises the liquid suction device as described above.

[0028] By adopting the above technical scheme, the liquid suction device has the advantages of fast response speed and short liquid suction time, so that the automatic chemiluminescence analysis device can complete high-speed testing on a large number of samples to be tested, and improve the testing efficiency.

[0029] Further, the photometric disc device is further included; the photometric disc device comprises a housing body installed on a rack, a photometric disc rotatingly arranged in the housing body, a photometric disc top cover arranged on the opening of the housing body; a plurality of reaction cups are arranged in the photometric disc, a liquid suction hole is arranged on the photometric disc top cover, the lower end of the mounting rack is fixed on the upper end of the photometric disc top cover, and the liquid suction needle and the liquid suction hole are arranged opposite to each other.

[0030] In summary, the technical scheme of the utility model has the following advantages:

[0031] 1. The independent linear motor is used as the driving part, the liquid suction operation can be automatically completed in a shorter time, and the rapid automatic liquid suction requirement of the large-scale high-speed chemiluminescence analysis equipment is matched;

[0032] 2. The plastic part is used as the support plate, the influence of the heat generated in the working process of the linear motor on the internal reaction or other modules of the photometric disc device can be avoided;

[0033] 3. The modular design and layout of the liquid suction device compress the volume of the liquid suction device, and the volume of the whole automatic chemiluminescence analysis equipment can be reduced. BRIEF DESCRIPTION OF DRAWINGS

[0034] In order to more clearly illustrate the specific embodiment of the utility model or the technical scheme in the prior art, the following will briefly introduce the drawings needed to be used in the specific embodiment or the prior art description, and obviously, the drawings in the following description are some embodiments of the utility model, and for those skilled in the art, other drawings can be obtained without creative labor on the basis of these drawings.

[0035] Figure 1 It is a schematic view of the connection relationship between the liquid suction device and the photometric disc device in the automatic chemiluminescence analysis equipment in the embodiment of the utility model.

[0036] Figure 2 It is a schematic view of the structure of the liquid suction device in the embodiment of the utility model.

[0037] The reference signs are explained as follows: 100, liquid suction device; 200, rack; 300, photometric disc device; 310, housing body; 320, photometric disc top cover; 110, mounting rack; 111, support plate; 112, motor mounting plate; 120, linear motor; 121, screw rod; 130, linear guide rail; 140, sliding seat; 151, liquid suction needle; 152, buffer seat; 153, needle sleeve; 154, locking part; 160, optical coupling switch; 170, optical coupling piece; 180, joint fixing plate; 190, pipeline joint. DETAILED DESCRIPTION

[0038] The technical solutions of the present application will be described clearly and completely in connection with the drawings. Obviously, the described embodiments are some of the embodiments of the present application, but not all the embodiments. Based on the embodiments of the present application, all the other embodiments obtained by those skilled in the art without creative labor fall within the scope of the present application.

[0039] In the description of the present application, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer" and the like indicate the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as limiting the present application. In addition, the terms "first", "second", "third" are only for the purpose of description, and cannot be understood as indicating or implying relative importance.

[0040] In the description of the present application, it should be noted that unless otherwise explicitly specified and limited, the terms "mounting", "connecting", "connecting" should be understood broadly, for example, it can be fixedly connected, or it can be detachably connected, or integrally connected; it can be mechanically connected, or it can be electrically connected; it can be directly connected, or it can be indirectly connected through an intermediate medium; it can be the communication inside two elements. For those skilled in the art, the specific meaning of the above terms in the present application can be understood according to the specific circumstances.

[0041] As shown in Figure 1 An automatic chemiluminescence analysis equipment shown in Fig. 2, comprising a liquid suction device 100, a rack 200 and a light measuring disc device 300; the light measuring disc device 300 is installed above the rack 200, and the liquid suction device 100 is installed above the light measuring disc device 300. Of course, the automatic chemiluminescence analysis equipment also includes a liquid injection device, a cup grabbing device and other devices not shown in the figure.

[0042] As shown in Figure 1As shown, the photometric disc device 300 includes a housing 310 mounted on the rack 200, a photometric disc (not shown) rotatably arranged in the housing 310, and a photometric disc cover 320 arranged above the opening of the housing 310. The photometric disc has a plurality of reaction cups (not shown) arranged therein, which are mixing, reaction and incubation sites for samples and reagents. The side wall of the photometric disc is provided with a plurality of photometric holes corresponding to the reaction cups, and the side wall of the housing 310 is fixed with a light signal measuring assembly (not shown) for measuring the light emission of the reaction cup through the photometric hole. The photometric disc cover 320 is provided with a liquid suction hole, and the liquid suction device 100 is used to suck liquid from the reaction cup in the photometric disc through the liquid suction hole in the photometric disc cover 320; the liquid suction needle 151 of the liquid suction device 100 is located directly above the liquid suction hole. During the liquid suction process of the liquid suction device 100, the liquid suction needle 151 extends into the reaction cup of the photometric disc through the liquid suction hole in the photometric disc cover 320 to suck liquid, and the liquid suction needle 151 can move upward through the liquid suction hole after completing a liquid suction operation. It should be noted that the specific structure of the photometric disc device 300, the liquid injection device and other devices such as the cup grabbing device is a conventional design known to those skilled in the art, and is not closely related to the application point of the present application, and will not be described here. The liquid suction device 100 mainly protected by the present application will be described in detail below.

[0043] As shown in Figure 1 and Figure 2 The liquid suction device 100 includes a mounting bracket 110, a linear motor 120, a sliding seat 140 and a liquid suction assembly. The mounting bracket 110 is fixed to the upper end of the photometric disc cover 320; the linear guide rail 130 is fixed to one side of the mounting bracket 110 and has the same driving direction as the linear motor 120; the sliding seat 140 is driven by the linear motor 120 to move linearly, and the sliding seat 140 is slidably connected to the linear guide rail 130 along the guide direction of the linear guide rail 130; the liquid suction assembly 100 is connected to the sliding seat 140, and the liquid suction assembly 100 is provided with a liquid suction needle 151 for absorbing liquid and moving linearly synchronously with the sliding seat 140.

[0044] In this liquid aspiration device, during the automatic liquid aspiration process, the linear motor 120 directly drives the sliding seat 140 and the aspiration needle 151 to move vertically up and down along the guide direction of the linear guide rail 130. When the aspiration needle 151 descends into the reaction cup, it aspirates the liquid in the reaction cup, realizing the automatic liquid aspiration operation of the automated chemiluminescence analysis equipment. Compared with the existing method of indirectly driving the aspiration needle 151 through a belt drive mechanism using a linear motor 120 to drive the sliding seat 140 and the aspiration needle 151, this method eliminates the intermediate mechanical transmission link between the motor and the aspiration needle 151, reducing transmission errors and lag. The response time of the aspiration needle 151 is greatly shortened, resulting in a more sensitive and rapid response. It can automatically complete the liquid aspiration operation in a shorter time, thus meeting the rapid automatic liquid aspiration requirements of large-scale high-speed automated chemiluminescence analysis equipment. This overcomes the problems of slow liquid aspiration response speed, slow liquid aspiration speed, and complex structure of existing liquid aspiration devices, which restrict the high-speed testing of fully automated chemiluminescence analysis equipment.

[0045] like Figure 1 and Figure 2 As shown, in some embodiments, the mounting bracket 110 includes a vertically arranged support plate 111 and a horizontally arranged motor mounting plate 112. The bottom end of the support plate 111 is fixed to the upper edge of the measuring optical disc top cover 320, and the motor mounting plate 112 is fixed to the top of the support plate 111 by screws. The linear motor 120 is mounted on the side of the motor mounting plate 112 facing away from the support plate 111. This design allows for modular design of the liquid aspiration device 100 and the measuring optical disc device 300, reducing the space occupied by the liquid aspiration device 100, and thus helping to reduce the overall size of the fully automated chemiluminescence analyzer. Furthermore, mounting the linear motor 120 on the side of the motor mounting plate 112 facing away from the support plate 111 keeps the linear motor 120 as far away from the measuring optical disc device 300 as possible, avoiding the influence of heat generated by the linear motor 120 during operation on the reactants inside the measuring optical disc device 300. In other alternative embodiments, the mounting bracket 110 is not limited to the above-described structure consisting of only a single support plate 111 and a single motor mounting plate 112. For example, two vertically arranged support plates 111 can also be arranged side by side, with the motor mounting plate 112 fixed to the top of the two support plates 111.

[0046] In some embodiments, the motor mounting plate 112 is a metal part, and the support plate 111 is a plastic part. The plastic support plate 111 can prevent the heat generated during the operation of the linear motor 120 from affecting the internal reactants or other devices of the optical disc measuring device 300.

[0047] In some embodiments, the support plate 111 is a frame-shaped structure with an internal hollow space, a portion of the sliding seat 140 is located in the internal hollow space of the support plate 111, and the linear guide rail 130 is fixed to one side of the support plate 111. In this way, the space of the support plate 111 can be fully utilized, the structural compactness of the liquid suction device 100 is improved, and the space occupation of the liquid suction device 100 is reduced.

[0048] In some embodiments, the mounting frame 110 is fixed with a position detection sensor, and the sliding seat 140 is fixed with a stroke stop piece that moves synchronously with the sliding seat 140. When the position detection sensor detects a stroke stop piece signal, the position detection sensor sends a sensing signal to the controller to instruct the controller to control the linear motor 120 to stop running. The position detection sensor and the stroke stop piece can limit the movement stroke of the sliding seat 140 and the liquid suction needle 151. Preferably, the position detection sensor is an optical coupling switch 160, and the stroke stop piece is an optical coupling piece 170. In alternative embodiments, the position detection sensor can also be a micro switch or a direct-acting stroke switch or other various forms of position detection sensors.

[0049] In some embodiments, the linear motor 120 is a linear stepping motor. The linear stepping motor has the advantages of small size, light weight, short response time, high transmission stiffness, stable thrust, high motion accuracy, small wear, long service life, and the like, and can be stably operated for a long time.

[0050] In some embodiments, the liquid suction assembly includes a buffer seat 152 fixed to the sliding seat 140 by a screw, a needle sleeve 153 sleeved and fixed outside the liquid suction needle 151, and a locking member 154 for locking the needle sleeve 153 on the buffer seat 152. The buffer seat 152 is provided with a through hole through which the liquid suction needle 151 passes. The liquid suction needle 151 is installed on the sliding seat 140 through the buffer seat 152, which can provide certain buffer protection to avoid damage to the liquid suction needle 151. The locking member 154 is arranged to facilitate replacement of the needle sleeve 153 and the liquid suction needle 151, and different models of liquid suction needles 151 can be selected as needed. The locking member 154 is specifically a locking nut.

[0051] In some embodiments, one side of the motor mounting plate 112 is further fixed with a connector fixing plate 180, the connector fixing plate 180 is installed with a pipeline connector 190, one end of the pipeline connector 190 can be connected with the needle sleeve 153, and the other end of the pipeline connector 190 can be connected with a liquid suction pump and a liquid collection cylinder. After the liquid suction needle 151 is inserted into the reaction cup, the liquid suction pump provides negative pressure, the liquid sucked by the liquid suction needle 151 flows to the liquid collection cylinder through the liquid guide pipe and the pipeline connector 190, and automatic liquid suction operation is realized.

[0052] In summary, the liquid suction device and the automatic chemiluminescence analysis equipment have the following advantages.

[0053] 1. The independent linear motor 120 is used as the lifting driving element, the liquid suction operation can be automatically completed in a shorter time, the automatic chemiluminescence analysis equipment can complete high-speed testing on a large number of samples to be tested, and the testing efficiency is improved; the problem that the liquid suction device 100 in the prior art is slow in response and liquid suction speed, thereby restricting the realization of high-speed testing of the automatic chemiluminescence analysis equipment is overcome.

[0054] 2. The support plate 111 is designed by using a plastic element, the influence of heat generated in the working process of the linear motor 120 on the internal reagent or other device modules of the photodisk device 300 can be avoided.

[0055] 3. The modular design layout of the liquid suction device 100 compresses the volume of the liquid suction device 100, and is beneficial to reducing the volume of the entire automatic chemiluminescence analysis equipment.

[0056] Obviously, the above embodiments are only examples for clearly illustrating, and are not intended to limit the embodiments. Based on the above description, other different forms of changes or variations can be made by those skilled in the art. Here, all the embodiments are not enumerated, and the changes or variations which are derived from the embodiments are still within the protection scope of the utility model.

Claims

1. A liquid absorbing device, characterized by comprising: The application relates to a liquid suction device. The device comprises a mounting frame (110), a linear motor (120) mounted on the mounting frame (110), a linear guide rail (130) fixed on the mounting frame (110) and having the same driving direction as the linear motor (120), a sliding seat (140) driven by the linear motor (120) to move linearly and connected to the linear guide rail (130) to slide along the guide direction of the linear guide rail (130), and a liquid suction assembly connected to the sliding seat (140) and provided with a liquid suction needle (151) for sucking liquid and moving linearly synchronously with the sliding seat (140). The mounting frame (110) comprises a vertical support plate (111) and a horizontal motor mounting plate (112), one end of the support plate (111) is fixed on a light measuring disc device (300), the motor mounting plate (112) is fixed on the other end of the support plate (111), and the linear motor (120) is mounted on the side of the motor mounting plate (112) away from the support plate (111). The support plate (111) is a plastic part. The support plate (111) is a frame-shaped structure with an internal hollow space, and at least a part of the sliding seat (140) is located in the hollow space inside the support plate (111). The mounting frame (110) is provided with a position detection sensor, and the sliding seat (140) is connected with a stroke stopper (170) moving synchronously with the sliding seat (140); when the position detection sensor detects the stroke stopper signal, the position detection sensor sends an induction signal to a controller to control the linear motor (120) to stop running.

2. The liquid absorbing device according to claim 1, wherein The position detection sensor is an optical coupling switch (160), and the stroke stopper is an optical coupling piece (170).

3. The liquid absorbing device according to claim 2, wherein The linear motor (120) is a linear stepping motor.

4. The liquid absorbing device according to claim 2, wherein The liquid suction assembly further comprises a buffer seat (152) fixed to the sliding seat (140), a needle sleeve (153) fixedly sleeved on the outside of the liquid suction needle (151), and a locking member (154) for locking the needle sleeve (153) on the buffer seat (152); the buffer seat (152) is provided with a through hole for the liquid suction needle (151) to pass through.

5. The liquid absorbing device according to claim 1, wherein The application further relates to a liquid suction device as claimed in any one of claims 1-8.

6. The liquid absorbing device according to claim 5, wherein The application further relates to a light measuring disc device (300), which comprises a housing (310) mounted on a rack (200), a light measuring disc rotatably arranged in the housing (310), and a light measuring disc top cover (320) arranged above the opening of the housing (310); the light measuring disc is provided with a plurality of reaction cups, the light measuring disc top cover (320) is provided with a liquid suction hole, the lower end of the mounting frame (110) is fixed to the upper end of the light measuring disc top cover (320), and the liquid suction needle (151) and the liquid suction hole are arranged opposite to each other.

7. The liquid absorbing device according to claim 5, wherein ​ 8. The liquid absorbing device according to claim 1, wherein ​ 9. An automated chemiluminescence analysis apparatus characterized by comprising: ​ 10. The automated chemiluminescence assay apparatus according to claim 9, wherein ​

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