Raw material sterilization equipment for pharmaceutical production

Abstract

The utility model relates to the technical field of medicine sterilization, and discloses raw material sterilization equipment for medicine production, which comprises a drying bin, the left end of the drying bin is fixedly connected with a connecting bin, the middle part of the top end of the drying bin is fixedly connected with a driving motor, and the driving end of the driving motor is fixedly connected with a transmission rod; a reciprocating screw rod is fixedly connected to the bottom end of the transmission rod, a moving frame is connected to the outer wall of the reciprocating screw rod through a moving set, a first filter screen is fixedly connected to the top end of the connecting bin, a plurality of circulating fans are fixedly connected to the inner wall of the first filter screen, and a wind shell is connected to the bottom end of the connecting bin through a conveying set; the left side of the top end of the drying bin is fixedly connected with a feeding pipe, and the right side of the top end of the drying bin is fixedly connected with an exhaust pipe. In the utility model, the raw material accumulation body is effectively depolymerized into a discrete particle state, so that the penetration rate of hot air is improved, the device is ensured to smoothly heat the drying bin, and the continuous circulating sterilization of hot air is ensured.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical sterilization technology, and in particular to raw material sterilization equipment used in pharmaceutical production. Background Technology

[0002] The quality and safety of medicines are directly related to people's health and safety. Raw materials used in the production of medicines, such as Chinese medicinal herbs and chemical raw materials, may be contaminated by various microorganisms, including bacteria, fungi, and viruses, during collection, transportation, and storage. If these microorganisms are not effectively killed, the raw material sterilization equipment will use high-temperature dry air to oxidize and denature the proteins in the microorganisms, causing them to die, thereby ensuring the normal use of medicines.

[0003] Existing sterilization equipment typically uses simple agitation devices such as stirring paddles and agitating rakes, which can only perform basic stirring or agitation functions and cannot meet the special needs of pharmaceutical raw materials during sterilization and drying. Many pharmaceutical raw materials are powders, granules, or fibers, and traditional agitation devices cannot effectively disperse these materials, resulting in uneven distribution of materials within the equipment.

[0004] In response to this technical problem, this application proposes a raw material sterilization device for pharmaceutical production. Utility Model Content

[0005] The purpose of this invention is to address the shortcomings of existing technologies by proposing a raw material sterilization device for pharmaceutical production. The raw material accumulation is effectively deagglomerated into discrete particles, ensuring improved hot air penetration and guaranteeing smooth heating of the drying chamber by the device, thus ensuring continuous circulation and sterilization of hot air.

[0006] To achieve the above objectives, the present invention provides the following technical solution:

[0007] A raw material sterilization device for pharmaceutical production includes a drying chamber. A connecting chamber is fixedly connected to the left end of the drying chamber. A drive motor is fixedly connected to the middle of the top of the drying chamber. A transmission rod is fixedly connected to the drive end of the drive motor. A reciprocating lead screw is fixedly connected to the bottom end of the transmission rod. A moving frame is connected to the outer wall of the reciprocating lead screw via a moving assembly. A filter screen is fixedly connected to the top of the connecting chamber. Several circulating fans are fixedly connected to the inner wall of the filter screen. A fan casing is connected to the bottom of the connecting chamber via a conveying assembly. A feeding pipe is fixedly connected to the left side of the top of the drying chamber. An exhaust pipe is fixedly connected to the right side of the top of the drying chamber. A sealing plate is connected to the inner wall of the feeding pipe via a sealing assembly.

[0008] Furthermore, the moving assembly includes a slider sleeved on the outer wall of the reciprocating lead screw, the outer wall of the slider being fixedly connected to the inner wall of the moving frame.

[0009] Furthermore, a fixed shell is fixedly connected to the bottom of the inner wall of the drying chamber, and the outer wall of the bottom of the movable frame is slidably connected to and penetrates the inner wall of the fixed shell.

[0010] Furthermore, a stirring blade is fixedly connected to the outer wall of the transmission rod, and a flipping plate is fixedly connected to all four sides of the outer wall of the movable frame.

[0011] Furthermore, a heater is installed at the front end of the connecting chamber and extends through it, and a controller is provided on the outer wall of the front end of the drying chamber.

[0012] Furthermore, the sealed assembly includes a fixed ring fixedly connected to the inner wall of the delivery tube, a spring fixedly connected to the bottom end of the fixed ring, the front end of the spring fixedly connected to the outer wall of the bottom end of the sealed plate, and the rear end of the sealed plate rotatably connected to the bottom end of the fixed ring.

[0013] Furthermore, a second filter screen is fixedly connected to the top of the exhaust pipe, and a third filter screen is fixedly connected to the top of the air casing.

[0014] Furthermore, the conveying assembly includes a conveying pipe fixedly connected to the bottom of the connecting chamber, and the right end of the conveying pipe is fixedly connected to and penetrates the outer wall of the air casing.

[0015] This utility model has the following beneficial effects:

[0016] 1. In this utility model, the chemical to be sterilized is put into the drying chamber through the feeding pipe. The drive motor is started, the transmission rod rotates, and the stirring blade rotates and stirs. At the same time, the transmission rod causes the reciprocating screw to rotate synchronously. The screw drives the slider, which makes the moving frame move back and forth along the inner side of the fixed shell. Its flipping plate flips the raw material. The stirring and flipping work together to fully disperse the raw material, so that it is heated evenly and can be fully sterilized.

[0017] 2. In this utility model, when the circulating fan starts, it draws in filtered air from filter screen one, heats it into hot air through the heater, pours it into the air casing through the delivery pipe, passes through filter screen three and enters the drying chamber to heat and sterilize the chemical raw materials. The spring force causes the sealing plate to close at the fixed ring to prevent the raw materials from leaking out. Filter screen two intercepts the raw materials and discharges the air in the chamber, ensuring that the device can smoothly heat the drying chamber. Attached Figure Description

[0018] Figure 1 This is a perspective view of the raw material sterilization equipment for pharmaceutical production proposed in this utility model.

[0019] Figure 2 This is a half-sectional view of the connecting compartment of the raw material sterilization equipment for pharmaceutical production proposed in this utility model;

[0020] Figure 3 This is a half-sectional view of the drying chamber of the raw material sterilization equipment for pharmaceutical production proposed in this utility model;

[0021] Figure 4 This is a half-sectional view of the movable frame of the raw material sterilization equipment for pharmaceutical production proposed in this utility model;

[0022] Figure 5 This is a cross-sectional view of the air casing of the raw material sterilization equipment for pharmaceutical production proposed in this utility model;

[0023] Figure 6 This is a half-sectional view of the feeding pipe of the raw material sterilization equipment for pharmaceutical production proposed in this utility model.

[0024] Legend:

[0025] 1. Drying chamber; 2. Connecting chamber; 3. Heater; 4. Feeding pipe; 5. Exhaust pipe; 6. Drive motor; 7. Filter screen one; 8. Transmission rod; 9. Fixing ring; 10. Filter screen two; 11. Stirring blade; 12. Fixing shell; 13. Conveying pipe; 14. Circulating fan; 15. Fan casing; 16. Filter screen three; 17. Reciprocating screw; 18. Moving frame; 19. Flipping plate; 20. Slider; 21. Spring; 22. Sealing plate. Detailed Implementation

[0026] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0027] Reference Figure 1 , Figure 3 and Figure 4 An embodiment of this utility model provides a raw material sterilization device for pharmaceutical production, comprising a drying chamber 1, a connecting chamber 2 fixedly connected to the left end of the drying chamber 1, a drive motor 6 fixedly connected to the middle of the top of the drying chamber 1, a transmission rod 8 fixedly connected to the drive end of the drive motor 6, a reciprocating screw 17 fixedly connected to the bottom end of the transmission rod 8, a slider 20 sleeved on the outer wall of the reciprocating screw 17, the outer wall of the slider 20 fixedly connected to the inner wall of the movable frame 18, a fixed shell 12 fixedly connected to the bottom end of the inner wall of the drying chamber 1, the outer wall of the bottom end of the movable frame 18 slidably connected to and penetrating the inner wall of the fixed shell 12, a stirring blade 11 fixedly connected to the outer wall of the transmission rod 8, and a flipping plate 19 fixedly connected to all four sides of the outer wall of the movable frame 18.

[0028] Specifically: After the chemicals to be sterilized are precisely added into the sealed drying chamber 1 through the dispensing pipe 4, the operator starts the drive motor 6. This motor drives the transmission rod 8 to rotate axially through the reduction mechanism 7. The transmission rod 8, connected by a keyway, synchronously drives two sets of stirring blades 11 to rotate circumferentially along the central axis of the drying chamber 1 at a speed of 15-25 r / min. Its spiral blade design can perform three-dimensional stirring of the chemical raw materials in the chamber. At the same time, the end of the transmission rod 8 is linked to the reciprocating screw 17 through the bevel gear set 16. The spiral groove of the reciprocating screw 17 and the slider 20... The guide pins form a precise fit, driving the moving frame 18 to reciprocate linearly along the linear guide rail 21 inside the fixed shell 12 by ±50mm. The eight sets of flipping plates 19 spaced apart on the moving frame 18 form a wave-like flipping trajectory during the reciprocating stroke, which, together with the rotational motion of the stirring blade 11, forms a compound motion mode. This bidirectional dynamic action causes the chemical raw materials in the drying chamber 1 to be simultaneously subjected to radial centrifugal throwing and axial wave-like pushing, effectively agglomerating the raw material accumulation into discrete particles, ensuring improved hot air penetration, and ultimately achieving uniform heating of the entire area of ​​the chemical raw materials during the sterilization and drying process.

[0029] Reference Figure 2 , Figure 5 and Figure 6 A filter screen 7 is fixedly connected to the top of the connecting chamber 2. Several circulating fans 14 are fixedly connected to the inner wall of the filter screen 7. A conveying pipe 13 is fixedly connected to the bottom of the connecting chamber 2. The right end of the conveying pipe 13 is fixedly connected to the outer wall of the fan casing 15 and passes through it. A dispensing pipe 4 is fixedly connected to the left side of the top of the drying chamber 1. An exhaust pipe 5 is fixedly connected to the right side of the top of the drying chamber 1. A fixing ring 9 is fixedly connected to the inner wall of the dispensing pipe 4. A spring 21 is fixedly connected to the bottom of the fixing ring 9. The front end of the spring 21 is fixedly connected to the outer wall of the bottom of the sealing plate 22. The rear end of the sealing plate 22 is rotatably connected to the bottom of the fixing ring 9. A heater 3 is installed at the front end of the connecting chamber 2 and passes through it. A controller is set on the outer wall of the front end of the drying chamber 1. A filter screen 10 is fixedly connected to the top of the exhaust pipe 5. A filter screen 16 is fixedly connected to the top of the fan casing 15.

[0030] Specifically: When the circulating fan 14 starts at a speed of 1200 r / min, the negative pressure generated by its centrifugal impeller draws in ambient air at a flow rate of 3.5 m / s from the filter screen 7. This filter screen is made of 304 stainless steel and has a multi-layer composite filtration structure with a precision of 5 μm, which can effectively intercept suspended particulate matter ≥ PM5 in the air. The pre-filtered air then enters the spiral duct 2, and when it passes through the high-efficiency electric heater 3, it is heated to the set temperature of 85±2℃ by the PID temperature control module to form clean hot air. The heated air is then transported to the annular fan housing 15 through the insulated conveying pipe 13 at a pressure of 0.8 MPa, and passes through 48 groups of evenly distributed filters on the surface of the fan housing. The conical nozzle 17 accelerates the material to 15 m / s and passes through the porous titanium alloy filter screen 16 with a pore size of 0.3 mm and an opening rate of 62%, forming a laminar flow state. Finally, it uniformly covers the surface of the material inside the drying chamber 1 at a 45° angle. During this process, the spring 21, through a pre-compression force of 50 N, pushes the silicone sealing ring 23 of the sealing plate 22 to tightly fit against the mirror flange of the fixing ring 9, forming an IP67-level seal. This ensures that the inside of the drying chamber 1 maintains a positive pressure environment of 0.02-0.05 MPa. Simultaneously, the double-layer sintered metal filter screen 10, with an outer pore size of 0.5 mm and an inner pore size of 0.2 mm, intercepts chemical raw material particles while allowing the 600 particles / cm² distributed on its surface to pass through. 2 Micropores of 0.8m 3 With an exhaust rate of / min, a dynamic gas-solid separation system is formed inside the drying chamber 1, which ensures continuous circulation of hot air for sterilization and avoids cross-contamination caused by raw material leakage.

[0031] Working Principle: When the chemicals to be sterilized are added into the drying chamber 1 through the dispensing pipe 4, the drive motor 6 is started, driving the transmission rod 8 to rotate. This rotation of the transmission rod 8 causes the stirring blade 11 to rotate, which in turn causes the reciprocating screw 17 to rotate synchronously. The reciprocating screw 17 then drives the slider 20, causing the moving frame 18 to reciprocate along the inner side of the fixed shell 12. During this movement, the moving frame 18 drives the flipping plate 19 to agitate the chemical materials in the drying chamber 1. Combined with the stirring of the stirring blade 11, this ensures the chemical materials in the drying chamber 1 are thoroughly dispersed, resulting in uniform heating and facilitating the sterilization process. The raw materials are thoroughly sterilized. When the circulating fan 14 starts, it draws in the filtered air from the filter screen 7 and heats it with the heater 3. The heated air is then pumped into the fan housing 15 through the delivery pipe 13 and passes through the filter screen 16 to heat the drying chamber 1. The hot air sterilizes the chemical raw materials. The spring 21 closes the sealing plate 22 at the fixing ring 9, preventing the chemical raw materials in the drying chamber 1 from leaking out. The filter screen 10 can intercept the chemical raw materials while expelling the air in the drying chamber 1, thus facilitating the heating of the drying chamber 1.

[0032] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. Raw material sterilization equipment for pharmaceutical production, comprising a drying bin (1), characterized in that: The left end of the drying bin (1) is fixedly connected with a connecting bin (2), the top end of the drying bin (1) is fixedly connected with a driving motor (6), the driving end of the driving motor (6) is fixedly connected with a transmission rod (8), the bottom end of the transmission rod (8) is fixedly connected with a reciprocating screw rod (17), the outer wall of the reciprocating screw rod (17) is connected with a moving frame (18) through a moving group, the top end of the connecting bin (2) is fixedly connected with a filter screen one (7), the inner wall of the filter screen one (7) is fixedly connected with a plurality of circulating fans (14), the bottom end of the connecting bin (2) is connected with a wind shell (15) through a conveying group, the top end of the drying bin (1) is fixedly connected with a feeding pipe (4) on the left side, the top end of the drying bin (1) is fixedly connected with an exhaust pipe (5) on the right side, the inner wall of the feeding pipe (4) is connected with a sealing plate (22) through a sealing group.

2. The raw material sterilization apparatus for pharmaceutical production according to claim 1, characterized by: The moving group comprises a sliding block (20) sleeved on the outer wall of the reciprocating screw rod (17), and the outer wall of the sliding block (20) is fixedly connected to the inner wall of the moving frame (18).

3. The raw material sterilization apparatus for pharmaceutical production according to claim 1, characterized by: The inner wall of the drying bin (1) is fixedly connected with a fixed shell (12) at the bottom end, and the bottom end of the moving frame (18) is slidingly connected to the inner wall of the fixed shell (12) and penetrates through.

4. The raw material sterilization apparatus for pharmaceutical production according to claim 1, characterized by: The outer wall of the transmission rod (8) is fixedly connected with a stirring blade (11), and the outer wall of the moving frame (18) is fixedly connected with a turnover plate (19) on four sides.

5. The raw material sterilization apparatus for pharmaceutical production according to claim 1, characterized by: The front end of the connecting bin (2) is provided with a heater (3) and penetrates through, and the outer wall of the front end of the drying bin (1) is provided with a controller.

6. The raw material sterilization apparatus for pharmaceutical production according to claim 1, characterized by: The sealing group comprises a fixed ring (9) fixedly connected to the inner wall of the feeding pipe (4), a spring (21) fixedly connected to the bottom end of the fixed ring (9), and the spring (21) is fixedly connected to the outer wall of the bottom end of the sealing plate (22), and the rear end of the sealing plate (22) is rotatably connected to the bottom end of the fixed ring (9).

7. The raw material sterilization apparatus for pharmaceutical production according to claim 1, characterized by: The top end of the exhaust pipe (5) is fixedly connected with a filter screen two (10), and the top end of the wind shell (15) is fixedly connected with a filter screen three (16).

8. The raw material sterilization apparatus for pharmaceutical production according to claim 1, characterized by: The conveying group comprises a conveying pipe (13) fixedly connected to the bottom end of the connecting bin (2), and the right end of the conveying pipe (13) is fixedly connected to the outer wall of the wind shell (15) and penetrates through.

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