Closed pathogen detection card box

Abstract

The utility model discloses a closed pathogen detection card box, and belongs to the field of pathogen detection. A closed pathogen detection card box comprises a shell and a carrier placed in the shell, a bearing plate is arranged in the shell, the carrier is placed on the surface of the bearing plate, a transmission structure is arranged in the carrier and can drive the bearing plate to move horizontally, a plurality of liquid taking devices are arranged at the top of the shell, and the liquid taking devices are arranged on the surface of the bearing plate. The bottom end of the liquid taking device penetrates through the shell and extends into the shell, the liquid taking device can enable a reagent stored in the liquid taking device to drop on the surface of the carrier in the horizontal moving process of the carrier, the transmission structure comprises a screw rod movably connected to the interior of the shell through a bearing, and a transmission block is fixedly connected to the bottom of the bearing plate; according to the utility model, on the basis of ensuring the sealing performance, reagents are sequentially dropped on the surface of a carrier for reaction, so that the safety and the accuracy of the detection process are ensured, and meanwhile, the interference of an external environment is avoided.

Description

Technical Field

[0001] This utility model relates to the field of pathogen detection technology, and in particular to a closed pathogen detection cartridge. Background Technology

[0002] Pathogen detection is the process of identifying the specific microorganism causing the infection through various laboratory testing methods. Pathogens include a variety of microorganisms such as bacteria, viruses, fungi, mycoplasma, chlamydia, and spirochetes. After these pathogens invade the human body through various routes, they can infect different organs, leading to disease. Detecting the nucleic acid of pathogens using polymerase chain reaction (PCR), nucleic acid probe hybridization technology, and real-time quantitative PCR technology is a crucial step in confirming the diagnosis in microbiological testing.

[0003] For example, patent application number 201611012226.9 published on the China Patent Network, entitled "A Closed Pathogen Detection Kit," includes an outer ring layer and an inner ring layer. The inner ring layer is fitted inside the outer ring layer, and a heat insulation layer is provided between the outer and inner ring layers. The heat insulation layer is filled with heat insulation cotton material. The bottom of the outer ring layer is fixed to a shock-absorbing pad. A temperature sensor is provided on one side of the inner wall of the inner ring layer, adjacent to a reagent tank. The reagent tank is located on a base and corresponds to a sampling device. The sampling device is movably connected to a slide rail, which is located on the top of the outer ring layer. A roller is connected to one side of the sampling device, and a knob is provided on the side wall of the outer ring layer, which is associated with the reagent tank. This invention features fast detection speed, good sealing, and can simultaneously detect multiple samples without cross-infection, effectively avoiding contamination by pathogenic microorganisms and operator infection.

[0004] However, the existing pathogen detection process requires the sequential addition of different reaction reagents. When the pipette used to carry the reagents is replaced, the sealing effect inside the cartridge is lost, causing the internal reagents to come into contact with and become contaminated by the external environment, affecting the accuracy of the detection and easily leading to the contamination of the working environment. Utility Model Content

[0005] The purpose of this invention is to solve the problem that the sealing effect of the cartridge is affected when changing a large number of reagents in the prior art, and to propose a closed pathogen detection cartridge.

[0006] To achieve the above objectives, the present invention adopts the following technical solution:

[0007] A closed pathogen detection cartridge, including a casing;

[0008] A carrier placed inside the outer shell;

[0009] The shell has a support plate inside, and the carrier is placed on the surface of the support plate. The carrier has a transmission structure inside, which can drive the support plate to move horizontally. The top of the shell has several liquid dispensers, the bottom of which penetrates the shell and extends into the interior of the shell. During the horizontal movement of the carrier, the liquid dispensers can drip the reagents stored inside onto the surface of the carrier.

[0010] As a preferred technical solution of this application, the transmission structure includes a screw movably connected inside the housing via a bearing, a transmission block fixedly connected to the bottom of the bearing plate, the transmission block being sleeved on the surface of the screw and threadedly connected to the screw, the left end of the screw penetrating the housing and extending to the left side of the housing, and a torsion block located outside the housing being fixedly connected to the left end of the screw.

[0011] As a preferred technical solution of this application, the left side of the outer shell is set to be hollow, and both ends of the left side of the outer shell are hinged to cover plates, which can seal the outer shell and also be used to take out the carrier.

[0012] As a preferred technical solution of this application, connecting blocks are fixedly connected to both sides of the bearing plate, and a pressure plate is movably connected to the surface of the connecting block through a pin. The side of the pressure plate away from the connecting block contacts the top of the carrier.

[0013] As a preferred technical solution of this application, both sides of the inner wall of the outer shell are fixedly connected to the extrusion frame. The left side of the extrusion frame is set to be inclined upward. During the movement of the bearing plate carrying the pressure plate, the pressure plate gradually contacts the smallest inclined surface of the extrusion frame and swings downward.

[0014] As a preferred technical solution of this application, a spring plate is fixedly connected to the inner side of the pressure plate, and the side of the spring plate away from the pressure plate is in contact with the surface of the bearing plate, and the spring plate can support the pressure plate.

[0015] As a preferred technical solution of this application, guide rods are fixedly connected to both ends of the right side of the outer shell. A sleeve block is sleeved on the surface of the guide rod. An extension plate is fixedly connected to the top of the sleeve block. The side of the extension plate away from the sleeve block extends to the top of the outer shell and is fixedly connected to liquid dispensing plates located on both sides of the liquid dispenser. There are two liquid dispensing plates, which are symmetrical to each other. The inner side of the liquid dispensing plate is set to be inclined inward. During the horizontal movement of the liquid dispensing plate, the inclined surface can squeeze the liquid dispenser.

[0016] As a preferred technical solution of this application, the right end of the screw passes through the outer shell and the sleeve block in sequence and extends to the right side of the sleeve block. The surface of the screw is threadedly connected to a push plate that is sleeved on the surface of the guide rod. The right side of the push plate can contact the surface of the sleeve block and push the sleeve block to move horizontally with the liquid dispensing plate.

[0017] As a preferred technical solution of this application, a support plate is fixedly connected to the right side of the outer shell, and the side of the support plate away from the outer shell extends to the right side of the screw and is movably connected to the screw.

[0018] As a preferred technical solution of this application, a compression spring is sleeved on the surface of the screw, located on the right side of the sleeve block, and the side of the compression spring away from the sleeve block contacts the surface of the support plate.

[0019] Compared with the prior art, the present invention provides a closed pathogen detection cartridge, which has the following beneficial effects:

[0020] 1. This closed pathogen detection cartridge allows reagents to be dropped sequentially onto the carrier surface for reaction while ensuring airtightness, thus ensuring the safety and accuracy of the detection process and avoiding interference from the external environment.

[0021] 2. This closed pathogen detection cartridge, through the combination of screw, transmission block and torsion block, realizes a simple and effective transmission structure, which can drive the carrier plate to move horizontally. It is not only easy to operate, but also can accurately control the moving distance and speed of the carrier, thereby ensuring that the reagent can be accurately dripped onto the designated position on the carrier surface.

[0022] 3. This closed pathogen detection cartridge features a perforated left side with a hinged cover, facilitating easy handling and placement of the carrier while maintaining the airtightness of the casing. This ensures the detection process is unaffected by the external environment and improves detection accuracy.

[0023] 4. This closed pathogen detection cartridge, by setting connecting blocks and pressure plates on both sides of the carrier plate, can effectively fix the carrier and prevent it from shifting or tipping over during movement, ensuring that the reagent can be accurately dripped onto the carrier surface, thus improving the reliability of the detection.

[0024] 5. This closed pathogen detection cartridge, through the cooperation of the squeezing frame and the pressure plate set on the inner wall of the outer shell, allows the pressure plate to gradually contact the smallest inclined surface of the squeezing frame and swing downward during the movement of the carrier plate. This not only further stabilizes the carrier but also avoids excessive pressure on the carrier by the pressure plate, thus protecting the integrity of the carrier.

[0025] 6. This closed pathogen detection cartridge has a spring plate inside the pressure plate to support it and prevent it from sagging or deforming when there is no external force. This ensures that the pressure plate can always maintain good contact with the carrier, thereby improving the stability of the detection.

[0026] 7. This closed pathogen detection cartridge, through the combination of guide rod, sleeve block, extension plate and liquid dispensing plate, realizes a mechanism that can automatically squeeze the liquid dispenser to release reagents, which not only simplifies the operation steps, but also improves the accuracy and consistency of reagent release.

[0027] 8. This closed pathogen detection cartridge, through a push plate connected by a screw thread, can contact the sleeve block and push it to move horizontally, thereby driving the liquid extraction plate to squeeze the liquid extractor, so that the release of reagents and the movement of the carrier can be carried out synchronously, ensuring the continuity and accuracy of detection.

[0028] 9. The closed pathogen detection cartridge provides stable support and limit for the screw through the support plate on the right side of the outer shell, preventing it from shifting or falling off during rotation. This ensures the stability and reliability of the transmission structure.

[0029] 10. This closed pathogen detection cartridge, through the compression spring sleeved on the screw surface, can provide a return force after the push plate moves, so that the sleeve block and liquid collection plate can return to the initial position, preparing for the next reagent release. This not only improves the reusability of the mechanism, but also simplifies the operation steps. Attached Figure Description

[0030] Figure 1 This is a schematic diagram of the structure of this utility model;

[0031] Figure 2 This is a schematic diagram of the right-side structure of this utility model;

[0032] Figure 3 This is a schematic diagram of the left-side structure of this utility model;

[0033] Figure 4 This is a partial structural schematic diagram of the present invention;

[0034] Figure 5 This is a bottom view of a partial structure of the present invention;

[0035] Figure 6 For the present utility model Figure 2 Enlarged structural diagram at point A in the middle.

[0036] In the diagram: 1. Outer shell; 2. Carrier; 3. Support plate; 4. Transmission structure; 5. Liquid dispenser; 6. Screw; 7. Transmission block; 8. Torsion block; 9. Cover plate; 10. Connecting block; 11. Pressure plate; 12. Squeezing frame; 13. Spring plate; 14. Guide rod; 15. Sleeve block; 16. Extension plate; 17. Liquid dispensing plate; 18. Pushing plate; 19. Support plate; 20. Compression spring. Detailed Implementation

[0037] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments of the present utility model. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of the present utility model without creative effort are within the protection scope of the present utility model.

[0038] Example 1:

[0039] Reference Figures 1-6 A closed pathogen detection cartridge, including a housing 1;

[0040] The carrier 2 is placed inside the outer casing 1;

[0041] The outer casing 1 has a support plate 3 inside, and the carrier 2 is placed on the surface of the support plate 3. The carrier 2 has a transmission structure 4 inside, which drives the support plate 3 to move horizontally. Several liquid dispensers 5 are located on the top of the outer casing 1, with their bottom ends penetrating the outer casing 1 and extending into its interior. During the horizontal movement of the carrier 2, the liquid dispensers 5 can drip the reagents stored inside onto the surface of the carrier 2. This ensures the reagents are dripped onto the surface of the carrier 2 sequentially for reaction while maintaining a tight seal, ensuring the safety and accuracy of the detection process and avoiding interference from the external environment. The transmission structure 4 includes a screw 6 movably connected to the inside of the outer casing 1 via a bearing, and the bottom of the support plate 3... A transmission block 7 is fixedly connected to the screw 6. The transmission block 7 is sleeved on the surface of the screw 6 and threadedly connected to the screw 6. The left end of the screw 6 passes through the outer shell 1 and extends to the left side of the outer shell 1. A torsion block 8 located outside the outer shell 1 is fixedly connected to the left end of the screw 6. The left side of the outer shell 1 is hollowed out. Both ends of the left side of the outer shell 1 are hinged to cover plates 9. The cover plates 9 can seal the outer shell 1 and are also used to remove the carrier 2. Connecting blocks 10 are fixedly connected to both sides of the bearing plate 3. A pressure plate 11 is movably connected to the surface of the connecting block 10 through a pin. The side of the pressure plate 11 away from the connecting block 10 contacts the top of the carrier 2. An extrusion frame 12 is fixedly connected to both sides of the inner wall of the outer shell 1. The left side of the extrusion frame 12 is provided with The pressure plate 11 is tilted upwards. As the support plate 3 carries the pressure plate 11, the pressure plate 11 gradually contacts the surface of the extrusion frame 12 with the smallest tilt and swings downwards. A spring plate 13 is fixedly connected to the inner side of the pressure plate 11. The side of the spring plate 13 away from the pressure plate 11 contacts the surface of the support plate 3. The spring plate 13 can support the pressure plate 11. Guide rods 14 are fixedly connected to both ends of the right side of the outer shell 1. A sleeve block 15 is sleeved on the surface of the guide rod 14. An extension plate 16 is fixedly connected to the top of the sleeve block 15. The side of the extension plate 16 away from the sleeve block 15 extends to the top of the outer shell 1 and is fixedly connected to the liquid dispensing plates 17 located on both sides of the liquid dispenser 5. There are two liquid dispensing plates 17, which are symmetrical to each other. The inner side of the liquid dispensing plate 17... The side is set to be inclined inward. During the horizontal movement of the liquid dispensing plate 17, the inclined surface can squeeze the liquid dispenser 5. The right end of the screw 6 passes through the outer shell 1 and the sleeve block 15 in sequence and extends to the right side of the sleeve block 15. The surface of the screw 6 is threadedly connected to a push plate 18 that is sleeved on the surface of the guide rod 14. The right side of the push plate 18 can contact the surface of the sleeve block 15 and push the sleeve block 15 to carry the liquid dispensing plate 17 to move horizontally. The right side of the outer shell 1 is fixedly connected to a support plate 19. The side of the support plate 19 away from the outer shell 1 extends to the right side of the screw 6 and is movably connected to the screw 6. The surface of the screw 6 is sleeved with a compression spring 20 located on the right side of the sleeve block 15. The side of the compression spring 20 away from the sleeve block 15 contacts the surface of the support plate 19.

[0042] Specifically, when this closed pathogen detection cartridge is in operation / use: First, the entire cartridge consists of an outer shell 1, inside which is a support plate 3. The carrier 2 to be tested is placed on the support plate 3. Multiple liquid dispensers 5 are installed on the top of the outer shell 1 for storing and releasing reagents. The cartridge is designed with a transmission structure 4 inside, the core of which is a screw 6 that is movably connected to the inside of the outer shell 1 via a bearing. A transmission block 7 is fixed to the bottom of the support plate 3. This transmission block 7 is sleeved on the screw 6 and threadedly connected to the screw 6. Therefore, when the screw 6 rotates, the transmission block 7 will move along the length of the screw 6, thereby driving the support plate 3 and the carrier 2 on it to move horizontally. The screw 6 is driven by a torsion block 8 fixed to the left end of the outer casing 1, which is manually rotated by the user. The left side of the outer casing 1 is designed to be hollow, with cover plates 9 at both ends, which are hinged to the outer casing 1 to maintain the airtightness of the outer casing 1 and facilitate the user to open the cover plates 9 to take out or put in the carrier 2. On both sides of the carrier plate 3, there are connecting blocks 10 fixed, and pressure plates 11 are movably connected to these connecting blocks 10 by pins. One side of the pressure plate 11 contacts the top of the carrier 2 to keep it stable during the movement of the carrier 2. The inner walls of the outer casing 1 are equipped with compression frames 12 on both sides, and the left side is designed to be inclined upwards. When the carrier plate 3 moves with the pressure plate 11, The pressure plate 11 gradually contacts the smallest inclined surface of the extrusion frame 12 and swings downward under its action, further stabilizing the carrier 2. When the carrier 2 is placed on the surface of the support plate 3, the torsion block 8 on the left side of the rotating screw 6 drives the screw 6 to rotate. The rotation of the screw 6 causes the support plate 3 and the carrier 2 on it to move horizontally. During the movement of the carrier 2, the pressure plate 11 maintains the stability of the carrier 2 under the action of the extrusion frame 12. At the same time, the rotation of the screw 6 also drives the push plate 18 to move. After the push plate 18 contacts the sleeve block 15, it pushes the sleeve block 15 and the liquid-collecting plate 17 on it to move horizontally. During the movement, the inclined surface of the liquid-collecting plate 17 squeezes the liquid collector. The liquid dispenser 5 at the bottom releases reagent onto the surface of the carrier 2. When the carrier 2 moves to the position of the next liquid dispenser 5, the push plate 18 continues to move, pushing the liquid dispensing plate 17 to squeeze the liquid dispenser 5 again and release the next reagent. This process is repeated until all the reagents are dripped onto the surface of the carrier 2 in sequence. After the reagents react with the carrier 2, the user can detect the presence of pathogens by observing the changes in the carrier 2. After the test is completed, the user can manually rotate the torsion block 8 of the screw 6 to return the push plate 18 to the initial position under the action of the compression spring 20, in preparation for the next test. At the same time, the cover plate 9 can be opened to remove the carrier 2 for further analysis or processing.

[0043] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. A closed pathogen detection cartridge, comprising a shell (1); a carrier (2) placed inside the shell (1); characterized in that The inside of the shell (1) is provided with a bearing plate (3), the carrier (2) is placed on the surface of the bearing plate (3), the inside of the carrier (2) is provided with a transmission structure (4), the transmission structure (4) can drive the bearing plate (3) to move horizontally, the top of the shell (1) is provided with a plurality of liquid taking devices (5), the bottom end of the liquid taking device (5) penetrates the shell (1) and extends to the inside of the shell (1), and the liquid taking device (5) can drop the reagent stored inside on the surface of the carrier (2) during the horizontal movement of the carrier (2).

2. The closed pathogen detection cartridge according to claim 1, wherein The transmission structure (4) comprises a screw rod (6) movably connected in the shell (1) through a bearing, the bottom of the bearing plate (3) is fixedly connected with a transmission block (7), the transmission block (7) is sleeved on the surface of the screw rod (6) and is in threaded connection with the screw rod (6), the left end of the screw rod (6) penetrates the shell (1) and extends to the left side of the shell (1), and the left end of the screw rod (6) is fixedly connected with a torsional block (8) located outside the shell (1).

3. The closed pathogen detection cartridge according to claim 1, wherein The left side of the shell (1) is provided in a hollow shape, both ends of the left side of the shell (1) are hingedly connected with cover plates (9), the cover plates (9) can seal the shell (1) and be used to take the carrier (2).

4. The closed pathogen detection cartridge according to claim 1, wherein Both sides of the bearing plate (3) are fixedly connected with connecting blocks (10), the surface of the connecting block (10) is movably connected with a pressing plate (11) through a pin shaft, and the side, away from the connecting block (10), of the pressing plate (11) is in contact with the top of the carrier (2).

5. The closed pathogen detection cartridge according to claim 4, wherein Both sides of the inner wall of the shell (1) are fixedly connected with extrusion frames (12), the left side of the extrusion frame (12) is provided in an upwardly inclined shape, and the pressing plate (11) gradually comes into contact with the smallest inclined surface of the extrusion frame (12) and swings downward during the movement of the bearing plate (3) carrying the pressing plate (11).

6. The closed pathogen detection cartridge according to claim 5, wherein, The inner side of the pressing plate (11) is fixedly connected with a spring plate (13), the side, away from the pressing plate (11), of the spring plate (13) is in contact with the surface of the bearing plate (3), and the spring plate (13) can support the pressing plate (11).

7. The closed pathogen detection cartridge according to claim 2, wherein Both ends of the right side of the shell (1) are fixedly connected with guide rods (14), the surface of the guide rod (14) is sleeved with a sleeve block (15), the top of the sleeve block (15) is fixedly connected with an extension plate (16), the side, away from the sleeve block (15), of the extension plate (16) extends to the top of the shell (1) and is fixedly connected with liquid taking plates (17) located on both sides of the liquid taking device (5), the number of the liquid taking plates (17) is two and they are mutually symmetrical, the inner side of the liquid taking plate (17) is provided in an inwardly inclined shape, and the liquid taking plate (17) can extrude the liquid taking device (5) by using the inclined surface during the horizontal movement of the liquid taking plate (17).

8. The closed pathogen detection cartridge according to claim 7, wherein The right end of the screw rod (6) penetrates the shell (1) and the sleeve block (15) in sequence and extends to the right side of the sleeve block (15), the surface of the screw rod (6) is threadedly connected with a pushing plate (18) sleeved on the surface of the guide rod (14), and the right side of the pushing plate (18) can contact the surface of the sleeve block (15) and push the sleeve block (15) to carry the liquid taking plate (17) to move horizontally.

9. The closed pathogen detection cartridge according to claim 8, wherein, The right side of the shell (1) is fixedly connected with a supporting plate (19), and the side, away from the shell (1), of the supporting plate (19) extends to the right side of the screw rod (6) and is movably connected with the screw rod (6).

10. The closed pathogen detection cartridge according to claim 9, wherein The surface of the screw rod (6) is sleeved with a compression spring (20) located at the right side of the sleeve block (15), and the side, away from the sleeve block (15), of the compression spring (20) is in contact with the surface of the supporting plate (19).

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