Nucleoside monomer mixing equipment
By designing the mixing and vibration components of the nucleoside monomer mixing device, the problem of uneven mixing of nucleoside monomers was solved, achieving uniform mixing and temperature monitoring, and improving mixing efficiency and stability.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-04-09
- Publication Date
- 2026-03-13
AI Technical Summary
In existing technologies, during the mixing process of nucleoside monomers, some nucleoside monomers tend to adhere to the inner wall of the mixing tank, resulting in uneven mixing and affecting the mixing effect.
A nucleoside monomer mixing device was designed, comprising a mixing component and a vibration component. The mixing is achieved by stirring with a stirring blade and scraping the inner wall of the raw material with a scraper. Temperature changes are monitored by a thermometer, and the vibration component prevents the material from adhering to the inner wall by vibrating up and down to shake off any adhering material.
This technology enables uniform mixing of nucleoside monomers and real-time temperature monitoring, improving mixing efficiency, avoiding the influence of adhesion to the inner wall, and ensuring the stability and efficiency of the mixing process.
Smart Images
Figure CN223988397U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the technical field of nucleoside monomer processing devices, specifically a nucleoside monomer mixing device. Background Technology
[0002] Nucleoside monomers are essential raw materials for the synthesis of genetic material (DNA and RNA) in living organisms. They consist of a base and a pentose sugar (ribose or deoxyribose) linked by a glycosidic bond. Nucleoside monomers include ordinary nucleoside monomers and modified nucleoside monomers. Ordinary nucleoside monomers are further divided into deoxyribonucleosides and ribonucleosides.
[0003] In the existing technology, the process of mixing nucleoside monomers usually involves putting the nucleoside monomers into the inside of a mixing tank and mixing them by rotating the stirring blades.
[0004] Existing technologies for mixing nucleoside monomers have some shortcomings. During the stirring process inside the mixing tank, some nucleoside monomers tend to adhere to the inner wall of the mixing tank, resulting in uneven mixing and affecting the mixing effect. To address this, we propose a nucleoside monomer mixing device. Utility Model Content
[0005] The purpose of this invention is to provide a nucleoside monomer mixing device that solves the problems mentioned in the background art.
[0006] To achieve the above objectives, this utility model provides the following technical solution: a nucleoside monomer mixing device, comprising a mounting plate and a mixing assembly disposed above the mounting plate. The mixing assembly includes a mixing tank disposed above the mounting plate, with a feed inlet at the top and a discharge outlet at the front. A valve is fixedly connected to the outer wall of the other end of the discharge outlet. A guide platform is fixedly connected to the bottom of the inner wall of the mixing tank. A first drive motor is fixedly connected to the top of the mixing tank. A first output shaft is fixedly connected to the output end of the first drive motor. The first output shaft movably passes through the top of the mixing tank and extends into the interior of the mixing tank. A stirring blade is fixedly connected to the outer wall of the middle part of the first output shaft. A connecting plate is fixedly connected to the bottom of the first output shaft. A scraper is fixedly connected to the other end of the connecting plate. The bottom of the scraper is slidably connected to the surface of the guide platform. By setting up the mixing assembly, the nucleoside monomers can be stirred and mixed by rotating the stirring blade.
[0007] Preferably, the mixing assembly further includes a temperature collector fixedly connected to the top of the mounting plate. A wire is fixedly connected to the top of the temperature collector, and the outer wall of the other end of the wire is fixedly connected to the inner wall of the side of the mixing tank. A thermometer is fixedly connected to the other end of the wire, and the side wall of the thermometer is fixedly connected to the inner wall of the mixing tank. During the stirring and mixing of nucleoside monomers inside the mixing tank, the operator can turn on the thermometer to measure the temperature inside the mixing tank. This facilitates real-time monitoring of the temperature inside the mixing tank during the stirring process. The monitored temperature is transmitted to the temperature collector via the wire, allowing the operator to observe the internal temperature of the mixing tank in real time and obtain the temperature change inside the mixing tank during the stirring and mixing of nucleoside monomers.
[0008] Preferably, a vibration assembly is provided at the bottom of the mounting plate. The vibration assembly includes a support frame fixedly connected to the bottom of the mounting plate. A second drive motor is fixedly connected to the inner wall of the bottom of the support frame. A second output shaft is fixedly connected to the output end of the second drive motor. A circular plate is fixedly connected to the top of the second output shaft. The outer wall of the circular plate is slidably connected to the inner wall of the mounting plate. A first protrusion is fixedly connected to the top of the circular plate. A second protrusion is slidably connected to the top of the first protrusion. The top of the second protrusion is fixedly connected to the bottom of the mixing tank. A limit block is fixedly connected to the outer wall of the bottom of the mixing tank. A limit rod is fixedly connected to the inner wall of the limit block. The bottom of the limit rod is fixedly connected to the top of the mounting plate. A spring is fixedly connected to the bottom of the limit block. The other end of the spring is fixedly connected to the top of the mounting plate. By providing the vibration assembly, when the nucleoside monomers are being stirred and mixed inside the mixing tank, to prevent the mixing tank from... Nucleoside raw materials adhere to the inner wall of the mixing drum, affecting the mixing effect. Therefore, it is necessary to vibrate the mixing drum to shake off the nucleoside raw materials adhering to the inner wall. At this time, the operator turns on the second drive motor, causing the second output shaft to rotate. During the rotation of the second output shaft, the circular plate rotates, which in turn causes the first protrusion to rotate. During the rotation of the first protrusion, its top contacts the outer wall of the second protrusion and squeezes the second protrusion, causing the second protrusion to move the mixing drum upward. This causes the limiting block on the outer wall of the mixing drum to move upward along the outer wall of the limiting rod. When the first protrusion stops squeezing the second protrusion, it moves downward under the action of the mixing drum's own gravity, causing the limiting block to move downward along the outer wall of the limiting rod and compressing the spring. Repeating this process can generate up-and-down vibration of the mixing drum, thereby facilitating the shaking off of the nucleoside raw materials adhering to the inner wall of the mixing drum during the mixing process.
[0009] Preferably, the bottom of the mounting plate is fixedly connected with two support legs, which are symmetrically distributed along the center plane of the mounting plate. By setting two support legs at the bottom of the mounting plate, a stable support function for the mounting plate can be achieved.
[0010] Preferably, the number of stirring blades is several sets, and the several sets of stirring blades are arranged in a linear array along the outer wall of the first output shaft. By setting multiple sets of stirring blades, the nucleoside raw materials inside the mixing tank can be uniformly stirred and mixed.
[0011] Preferably, the bottom of the first output shaft is fixedly connected to the top of the connecting plate, and the bottom of the connecting plate is fixedly connected to the top of one end of the scraper.
[0012] Preferably, the outer wall of the circular plate is adapted to the inner wall of the mounting plate, the top of the circular plate is fixedly connected to the bottom of the first protrusion, and the top of the first protrusion is slidably connected to the bottom of the second protrusion.
[0013] Preferably, there are six limiting blocks, all of equal size, arranged in a circumferential array along the central axis of the mixing drum. By setting six limiting blocks, the mixing drum can be limited during the up-and-down vibration process, thereby improving the stability of the mixing drum during the up-and-down vibration process.
[0014] This invention provides a nucleoside monomer mixing device. This nucleoside monomer mixing device has the following beneficial effects:
[0015] (1) This nucleoside monomer mixing equipment, by setting up a mixing component, allows the operator to feed the nucleoside raw material into the mixing tank from the inside of the feed inlet when it is necessary to stir and mix the nucleoside monomer. Then, by turning on the first drive motor, the first output shaft is driven to rotate. During the rotation of the first output shaft, the nucleoside raw material can be stirred and mixed. When the first output shaft rotates, it also drives the connecting plate to rotate. During the rotation of the connecting plate, it causes the scraper to rotate, so that the scraper can scrape the nucleoside raw material on the surface of the guide platform, so that the mixed nucleoside monomer falls into the through groove inside the guide platform. After the nucleoside monomer is mixed, By opening the valve, the operator can discharge the nucleoside raw material from the discharge port, thereby collecting the nucleoside raw material and improving the mixing effect of the device on nucleoside monomers. During the stirring and mixing of nucleoside monomers inside the mixing tank, the operator can turn on the thermometer to measure the temperature inside the mixing tank. This allows for real-time monitoring of the temperature inside the mixing tank during the stirring process. The monitored temperature is transmitted to the temperature collector via a wire, allowing the operator to observe the temperature inside the mixing tank in real time and obtain the temperature change inside the mixing tank during the stirring and mixing of nucleoside monomers.
[0016] (2) This nucleoside monomer mixing equipment, by setting a vibration component, when the nucleoside monomer is being stirred and mixed inside the mixing tank, in order to avoid the nucleoside raw material adhering to the inner wall of the mixing tank and thus affecting the stirring effect, it is necessary to vibrate the mixing tank to facilitate the shaking off of the nucleoside raw material on the inner wall of the mixing tank. At this time, the operator turns on the second drive motor to cause the second output shaft to rotate. During the rotation of the second output shaft, the circular plate will rotate, and during the rotation of the circular plate, the first protrusion will rotate. During the rotation of the first protrusion, its top will contact the outer wall of the second protrusion and squeeze the second protrusion, causing the second protrusion to move the mixing tank upward, causing the limiting block on the outer wall of the mixing tank to move upward along the outer wall of the limiting rod. When the first protrusion no longer squeezes the second protrusion, it will move downward under the action of the mixing tank's own gravity, and cause the limiting block to move downward along the outer wall of the limiting rod, and compress the spring. Repeating this process can achieve up and down vibration of the mixing tank, thereby facilitating the shaking off of the nucleoside raw material adhering to the inner wall of the mixing tank during the stirring process. Attached Figure Description
[0017] Figure 1 This is a three-dimensional structural diagram of the present invention;
[0018] Figure 2 This is a partial cross-sectional view of the present invention;
[0019] Figure 3This is a partial cross-sectional view of the hybrid component in this utility model;
[0020] Figure 4 This is a schematic diagram of the structure of the hybrid component in this utility model;
[0021] Figure 5 This is a schematic diagram of the bottom structure of the vibration component in this utility model;
[0022] Figure 6 This is a schematic diagram of the vibration component in this utility model.
[0023] In the diagram: 1. Mounting plate; 2. Support leg; 31. Mixing component; 311. Mixing tank; 312. Feed inlet; 313. Discharge outlet; 314. Valve; 315. Temperature collector; 316. Wire; 317. Thermometer; 318. First drive motor; 319. First output shaft; 3110. Stirring blade; 3111. Guide platform; 3112. Connecting plate; 3113. Scraper; 32. Vibration component; 321. Support frame; 322. Second drive motor; 323. Second output shaft; 324. Circular plate; 325. First protrusion; 326. Second protrusion; 327. Limiting block; 328. Limiting rod; 329. Spring. Detailed Implementation
[0024] To provide a clearer understanding of the technical features, objectives, and effects of this utility model, the specific embodiments of this utility model are now described with reference to the accompanying drawings.
[0025] A preferred embodiment of the nucleoside monomer mixing device provided by this utility model is, for example... Figures 1 to 6As shown: A nucleoside monomer mixing device includes a mounting plate 1 and a mixing assembly 31 disposed above the mounting plate 1. The mixing assembly 31 includes a mixing tank 311 disposed above the mounting plate 1. The top of the mixing tank 311 has a feed inlet 312, and the front of the mixing tank 311 has a discharge outlet 313. A valve 314 is fixedly connected to the outer wall of the other end of the discharge outlet 313. A guide platform 3111 is fixedly connected to the bottom of the inner wall of the mixing tank 311. A first drive motor 318 is fixedly connected to the top of the mixing tank 311. A first output shaft 319 is fixedly connected to the output end of the first drive motor 318. The first output shaft 319 movably passes through the top of the mixing tank 311 and extends into the interior of the mixing tank 311. A stirring blade 3110 is fixedly connected to the outer wall of the middle part of the first output shaft 319. A connecting plate 3112 is fixedly connected to the bottom of the first output shaft 319. A scraper 3113 is fixedly connected to the other end of the connecting plate 3112. The bottom of the scraper 3113 is connected to the guide platform 3111. The surface sliding connection of 11, through the setting of the mixing component 31, when it is necessary to stir and mix nucleoside monomers, the operator puts the nucleoside raw material into the mixing tank 311 from the inside of the feed port 312. Then, by turning on the first drive motor 318, the first output shaft 319 is driven to rotate. During the rotation of the first output shaft 319, the nucleoside raw material can be stirred and mixed. When the first output shaft 319 rotates, it also drives the connecting plate 3112 to rotate. During the rotation of the connecting plate 3112, the scraper 3113 will rotate, so that the scraper 3113 can scrape the nucleoside raw material on the surface of the guide platform 3111, so that the mixed nucleoside monomers fall into the through groove inside the guide platform 3111. After the nucleoside monomers are mixed, the operator can open the valve 314 to make the nucleoside raw material discharge from the discharge port 313, thereby realizing the collection of nucleoside raw materials and improving the mixing effect of the device on nucleoside monomers.
[0026] The mixing assembly 31 also includes a temperature collector 315 fixedly connected to the top of the mounting plate 1. A wire 316 is fixedly connected to the top of the temperature collector 315. The outer wall of the other end of the wire 316 is fixedly connected to the inner wall of the side of the mixing tank 311. A thermometer 317 is fixedly connected to the other end of the wire 316. The side wall of the thermometer 317 is fixedly connected to the inner wall of the mixing tank 311. During the stirring and mixing of nucleoside monomers inside the mixing tank 311, the operator can turn on the thermometer 317 to measure the temperature inside the mixing tank 311. This facilitates real-time monitoring of the temperature inside the mixing tank 311 during the stirring process. The monitored temperature is transmitted to the temperature collector 315 through the wire 316, allowing the operator to observe the internal temperature of the mixing tank 311 in real time and obtain the temperature change inside the mixing tank 311 during the stirring and mixing of nucleoside monomers.
[0027] A preferred embodiment of the nucleoside monomer mixing device provided by this utility model is, for example... Figures 1 to 6 As shown: A vibration assembly 32 is provided at the bottom of the mounting plate 1. The vibration assembly 32 includes a support frame 321 fixedly connected to the bottom of the mounting plate 1. A second drive motor 322 is fixedly connected to the inner wall of the bottom of the support frame 321. A second output shaft 323 is fixedly connected to the output end of the second drive motor 322. A circular plate 324 is fixedly connected to the top of the second output shaft 323. The outer wall of the circular plate 324 is slidably connected to the inner wall of the mounting plate 1. A first protrusion 325 is fixedly connected to the top of the circular plate 324. A second protrusion 326 is slidably connected to the top of the first protrusion 325. The top of the two protrusions 326 is fixedly connected to the bottom of the mixing tank 311. A limiting block 327 is fixedly connected to the outer wall of the bottom of the mixing tank 311. A limiting rod 328 is fixedly connected to the inner wall of the limiting block 327. The bottom of the limiting rod 328 is fixedly connected to the top of the mounting plate 1. A spring 329 is fixedly connected to the bottom of the limiting block 327. The other end of the spring 329 is fixedly connected to the top of the mounting plate 1. By setting the vibration component 32, when the nucleoside monomer is being stirred and mixed inside the mixing tank 311, in order to prevent the nucleoside raw material from adhering to the inner wall of the mixing tank 311, the vibration component 32 is used. This can affect the mixing effect, so the mixing tank 311 needs to be vibrated to shake off the nucleoside raw materials on the inner wall of the mixing tank 311. At this time, the operator turns on the second drive motor 322, causing the second output shaft 323 to rotate. During the rotation of the second output shaft 323, the circular plate 324 will rotate, and during the rotation of the circular plate 324, the first protrusion 325 will rotate. During the rotation of the first protrusion 325, its top will contact the outer wall of the second protrusion 326 and squeeze the second protrusion 326, so that the second The protrusion 326 moves the mixing barrel 311 upward, causing the limiting block 327 on the outer wall of the mixing barrel 311 to move upward along the outer wall of the limiting rod 328. When the first protrusion 325 stops pressing the second protrusion 326, it will move downward under the action of the mixing barrel 311's own weight, causing the limiting block 327 to move downward along the outer wall of the limiting rod 328 and compress the spring 329. Repeating this process can achieve up-and-down vibration of the mixing barrel 311, thereby facilitating the shaking off of the nucleoside raw materials adhering to the inner wall of the mixing barrel 311 during the stirring process.
[0028] Furthermore, the bottom of the mounting plate 1 is fixedly connected with a support leg 2. There are two support legs 2, which are symmetrically distributed along the center plane of the mounting plate 1. By setting two support legs 2 at the bottom of the mounting plate 1, a stable support function for the mounting plate 1 can be achieved.
[0029] Furthermore, there are several sets of stirring blades 3110, and these sets of stirring blades 3110 are arranged in a linear array along the outer wall of the first output shaft 319. By setting multiple sets of stirring blades 3110, the nucleoside raw materials inside the mixing tank 311 can be uniformly stirred and mixed.
[0030] Furthermore, the bottom of the first output shaft 319 is fixedly connected to the top of the connecting plate 3112, and the bottom of the connecting plate 3112 is fixedly connected to the top of one end of the scraper 3113.
[0031] Furthermore, the outer wall of the circular plate 324 is adapted to the inner wall of the mounting plate 1, the top of the circular plate 324 is fixedly connected to the bottom of the first protrusion 325, and the top of the first protrusion 325 is slidably connected to the bottom of the second protrusion 326.
[0032] In addition, there are six limit blocks 327, all of equal size, arranged in a circular array along the central axis of the mixing barrel 311. By setting six limit blocks 327, the mixing barrel 311 can be limited during the up-and-down vibration process, thereby improving the stability of the mixing barrel 311 during the up-and-down vibration process.
[0033] Working principle: When it is necessary to stir and mix nucleoside monomers, the operator puts the nucleoside raw material into the mixing tank 311 through the inlet 312. Then, by turning on the first drive motor 318, the first output shaft 319 is rotated. During the rotation of the first output shaft 319, the nucleoside raw material can be stirred and mixed. When the first output shaft 319 rotates, it also drives the connecting plate 3112 to rotate. During the rotation of the connecting plate 3112, the scraper 3113 rotates, so that the scraper 3113 can scrape the nucleoside raw material on the surface of the guide platform 3111, so that the mixed nucleoside monomers fall into the through groove inside the guide platform 3111. After the nucleoside monomers are mixed, the operator opens the valve 314 to discharge the nucleoside raw material from the discharge port 313, thereby collecting the nucleoside raw material and improving the mixing effect of the device on nucleoside monomers.
[0034] During the mixing of nucleoside monomers inside the mixing tank 311, the operator turns on the thermometer 317 to measure the temperature inside the mixing tank 311. This allows for real-time monitoring of the temperature inside the mixing tank 311 during the mixing process. The monitored temperature is transmitted to the temperature collector 315 via the wire 316, enabling the operator to observe the internal temperature of the mixing tank 311 in real time and obtain the temperature change inside the mixing tank 311 during the mixing of nucleoside monomers.
[0035] During the mixing of nucleoside monomers inside the mixing tank 311, to prevent the nucleoside raw materials from adhering to the inner wall of the mixing tank 311 and thus affecting the mixing effect, it is necessary to vibrate the mixing tank 311 to shake off the nucleoside raw materials from the inner wall of the mixing tank 311. At this time, the operator turns on the second drive motor 322, causing the second output shaft 323 to rotate. During the rotation of the second output shaft 323, the circular plate 324 will rotate, and during the rotation of the circular plate 324, the first protrusion 325 will rotate. During the rotation of the first protrusion 325, its top will contact the second protrusion 325. The first protrusion 325 contacts the outer wall of the mixing drum 311 and presses the second protrusion 326, causing the second protrusion 326 to move upward with the mixing drum 311. This causes the limiting block 327 on the outer wall of the mixing drum 311 to move upward along the outer wall of the limiting rod 328. When the first protrusion 325 stops pressing the second protrusion 326, the mixing drum 311 will move downward under its own weight, causing the limiting block 327 to move downward along the outer wall of the limiting rod 328 and compress the spring 329. Repeating this process can generate up-and-down vibration of the mixing drum 311, thereby facilitating the shaking off of the nucleoside raw materials adhering to the inner wall of the mixing drum 311 during the stirring process.
[0036] The above description is merely an illustrative embodiment of this utility model and is not intended to limit the scope of this utility model. Any equivalent changes and modifications made by those skilled in the art without departing from the concept and principles of this utility model should fall within the protection scope of this utility model. Furthermore, it should be noted that the components of this utility model are not limited to the overall application described above. Each technical feature described in the specification of this utility model can be used individually or in combination as needed. Therefore, this utility model naturally covers other combinations and specific applications related to this application.
Claims
1. A nucleoside monomer mixing apparatus comprising a mounting plate (1) and a mixing assembly (31) disposed above the mounting plate (1), characterised in that: The mixing assembly (31) comprises a mixing barrel (311) arranged above the mounting plate (1), the top of the mixing barrel (311) is provided with an inlet (312), the front of the mixing barrel (311) is provided with a discharge port (313), the other end of the discharge port (313) is fixedly connected with a valve (314), the inner wall of the bottom of the mixing barrel (311) is fixedly connected with a guide table (3111), the top of the mixing barrel (311) is fixedly connected with a first driving motor (318), the output end of the first driving motor (318) is fixedly connected with a first output shaft (319), the first output shaft (319) is movably penetrated through the top of the mixing barrel (311) and extends into the interior of the mixing barrel (311), the middle outer wall of the first output shaft (319) is fixedly connected with a stirring blade (3110), the bottom of the first output shaft (319) is fixedly connected with a connecting plate (3112), the other end of the connecting plate (3112) is fixedly connected with a scraper (3113), and the bottom of the scraper (3113) is slidably connected with the surface of the guide table (3111).
2. A nucleoside monomer mixing apparatus according to claim 1, wherein: The mixing assembly (31) further comprises a temperature collector (315) fixedly connected to the top of the mounting plate (1), the top of the temperature collector (315) is fixedly connected with a wire (316), the other end of the wire (316) is fixedly connected with the side inner wall of the mixing barrel (311), and the other end of the wire (316) is fixedly connected with a temperature measuring instrument (317).
3. The nucleoside monomer mixing apparatus of claim 1, wherein: The bottom of the mounting plate (1) is provided with a vibration assembly (32), the vibration assembly (32) comprises a support frame (321) fixedly connected to the bottom of the mounting plate (1), the bottom inner wall of the support frame (321) is fixedly connected with a second driving motor (322), the output end of the second driving motor (322) is fixedly connected with a second output shaft (323), the top of the second output shaft (323) is fixedly connected with a circular plate (324), the outer wall of the circular plate (324) is slidably connected with the inner wall of the mounting plate (1), the top of the circular plate (324) is fixedly connected with a first protrusion (325), the top of the first protrusion (325) is slidably connected with a second protrusion (326), the top of the second protrusion (326) is fixedly connected with the bottom of the mixing barrel (311), the outer wall of the bottom of the mixing barrel (311) is fixedly connected with a limiting block (327), the inner wall of the limiting block (327) is fixedly connected with a limiting rod (328), the bottom of the limiting rod (328) is fixedly connected with the top of the mounting plate (1), the bottom of the limiting block (327) is fixedly connected with a spring (329), and the other end of the spring (329) is fixedly connected with the top of the mounting plate (1).
4. The nucleoside monomer mixing apparatus of claim 1, wherein: The bottom of the mounting plate (1) is fixedly connected with support legs (2), the number of the support legs (2) is two, and the two support legs (2) are distributed in a symmetrical manner along the center of the mounting plate (1).
5. The nucleoside monomer mixing apparatus of claim 1, wherein: The number of the stirring blades (3110) is several groups, and the several groups of the stirring blades (3110) are linearly arranged along the outer wall of the first output shaft (319).
6. The nucleoside monomer mixing apparatus of claim 1, wherein: The bottom of the first output shaft (319) is fixedly connected with the top of the connecting plate (3112), and the bottom of the connecting plate (3112) is fixedly connected with the top of one end of the scraper (3113).
7. The nucleoside monomer mixing apparatus of claim 3, wherein: The outer wall of the circular plate (324) is matched with the inner wall of the mounting plate (1), the top of the circular plate (324) is fixedly connected with the bottom of the first protrusion (325), and the top of the first protrusion (325) is slidingly connected with the bottom of the second protrusion (326).
8. The nucleoside monomer mixing apparatus of claim 3, wherein: The number of the limiting blocks (327) is six, the six limiting blocks (327) are equal in size, and the six limiting blocks (327) are circularly arranged along the central axis of the mixing barrel (311).