NGS detection sample collector

By designing an NGS sample collector with a triangular collection component and a conical collection frame, the problems of leakage and contamination during sample transfer were solved, achieving aseptic collection and protection of samples.

CN224001396UActive Publication Date: 2026-03-17JIANGSU YIMI BIOTECHNOLOGY CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-03-07
Publication Date
2026-03-17

AI Technical Summary

Technical Problem

Existing samplers are prone to leakage and contamination by external impurities during sample transfer, leading to sample contamination.

Method used

An NGS sample collector was designed, which uses a triangular collection component and a conical collection frame. Impurities are prevented from entering by the limiting of the rotating plate and the guiding of the guide plate, and the sample is collected by the conical groove to avoid leakage.

Benefits of technology

It effectively blocks external impurities, prevents sample contamination, and ensures the integrity and purity of the sample during the transfer process.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of NGS detection, and discloses an NGS detection sample collector which comprises a collector assembly, a lifting sampling assembly, a lower collecting assembly and a collecting assembly, the collector assembly comprises a shell, a handle is installed on the outer wall of the shell, a cover plate is arranged on the top of the shell, and a positioning groove is formed in the bottom of the cover plate; according to the NGS detection sample collector, the symmetrical rotating plates are arranged on the outer walls of the two sides of the triangular collecting assembly, the triangular collecting assembly can be limited and protected by the triangular collecting assembly in the storage process, when the triangular collecting assembly descends, the rotating plates can be opened, external impurities can be effectively separated, and the collection efficiency of the NGS detection sample collector is improved. Furthermore, the impurity blocking capability of the equipment can be effectively improved, and the impurities can be effectively prevented from being collected together; the collecting frame is a conical groove, so that after the collecting frame is in contact with the sample, the medicine can be collected, and the leakage of the medicine can be effectively avoided.
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Description

Technical Field

[0001] This utility model relates to the field of NGS detection technology, specifically to an NGS detection sample collector. Background Technology

[0002] Sterility testing is a method for checking whether drugs, medical devices, raw materials, excipients, and other products subject to pharmacopoeia requirements are sterile. Traditional sterility testing methods mainly include pharmacopoeia sterility testing, adenosine triphosphate (ATP) bioluminescence assay, and nucleic acid amplification assay, but different methods have their own characteristics and limitations (Song Guangyan, Feng Zhen, Pan Yingying, Research on the Application of Flow Cytometry in Drug Sterility Testing. Chinese Pharmacist, 2012, 21(2):p.342-345). In the fields of drug and medical device production, distribution, and regulation, sterility testing is a necessary means to ensure drug quality and reduce adverse drug reactions, especially for high-risk sterile preparations, where sterility testing is of great significance.

[0003] Existing samplers are prone to leakage during sample transfer when collecting cell-derived drugs. Furthermore, external impurities are also collected along with the sampler during the collection process, which can easily lead to sample contamination. Therefore, an NGS detection sample collector is proposed. Utility Model Content

[0004] This utility model provides the following technical solution: an NGS sample collector, comprising a collector assembly, a lifting sampling assembly, a lower collection assembly, and a collection assembly.

[0005] As a preferred technical solution of this utility model, the collector assembly includes a housing, a handle is installed on the outer wall of the housing, a cover plate is provided on the top of the housing, a positioning groove is installed on the bottom of the cover plate, a guide plate is provided on the inner wall of the housing, and a positioning post is provided on the inner wall of the housing.

[0006] As a preferred technical solution of this utility model, the lifting sampling assembly includes a main guide block disposed on the inner wall of the housing, a connecting rod installed on the top of the main guide block, a cutting board installed on the side of the connecting rod away from the main guide block, a limiting groove formed on the outer wall of the main guide block, a guide groove formed on the outer wall of the main guide block, a telescopic rod provided on the inner wall of the limiting groove, a U-shaped positioning frame installed on the outer wall of the telescopic rod, and a spring sleeved on the outer wall of the telescopic rod.

[0007] As a preferred technical solution of this utility model, the lower collection component includes a triangular collection component disposed on the outer wall of the main guide block, the outer wall of the triangular collection component is provided with a rotating plate, and the inner wall of the rotating plate is equipped with a rotating component.

[0008] As a preferred technical solution of this utility model, the rotating assembly includes a left connecting block disposed on the outer wall of the rotating plate, a left connecting arm installed on the outer wall of the left connecting block, a right connecting block installed on the side of the rotating plate away from the left connecting block, a right connecting arm installed on the outer wall of the right connecting block, and a positioning shaft provided on the outer wall of the right connecting arm.

[0009] As a preferred embodiment of this utility model, the acquisition component includes an installation shaft disposed on the outer wall of the main guide block, an extension rod mounted on the side of the installation shaft away from the main guide block, a connecting plate mounted on the side of the extension rod away from the installation shaft, a fixing rod disposed on the outer wall of the connecting plate, and an acquisition frame disposed on the outer wall of the fixing rod.

[0010] As a preferred embodiment of this utility model, the guide plate and the positioning post are symmetrically distributed on the inner wall of the shell, and the guide plate and the main guide block are slidably connected.

[0011] As a preferred embodiment of this utility model, the extension rod and the connecting plate are integrated into one device, and multiple fixing rods are distributed in a circumferential array on the outer wall of the connecting plate.

[0012] As a preferred embodiment of this utility model, the positioning shaft passes through the left connecting arm and the right connecting arm, and the left connecting arm and the right connecting arm are rotatably connected.

[0013] As a preferred embodiment of this utility model, the rotating plates are symmetrically distributed on the outer wall of the triangular collecting assembly, and the rotating plates are rotatably connected to the triangular collecting assembly.

[0014] In a preferred embodiment of this utility model, the limiting groove is sleeved with the positioning post, and the limiting groove and the positioning post are slidably connected.

[0015] Compared with the prior art, the present invention has the following beneficial effects:

[0016] This NGS sample collector features symmetrical rotating plates on the outer walls of a triangular collection component. During storage, the triangular collection component is protected by its own rotating plates, which open as it descends to effectively separate external impurities. This enhances the device's ability to block impurities and prevents them from being collected simultaneously. Furthermore, the collection rack has a conical groove, allowing it to collect the drug after contacting the sample, effectively preventing drug leakage. Attached Figure Description

[0017] Figure 1 A schematic diagram of a three-dimensional structure of an NGS sample collector;

[0018] Figure 2 This is a schematic diagram of the collector component in an NGS sample collector.

[0019] Figure 3 This is a schematic diagram of the lifting sampling component in an NGS sample collector.

[0020] Figure 4 This is a schematic diagram of the lower collection component in an NGS sample collector.

[0021] Figure 5 This is a schematic diagram of the rotating component in an NGS sample collector;

[0022] Figure 6 This is a schematic diagram of the acquisition component in an NGS sample acquisition device.

[0023] In the diagram: 100, collector assembly; 110, housing; 120, handle; 130, cover plate; 140, positioning groove; 150, guide plate; 160, positioning column; 200, lifting sampling assembly; 210, connecting rod; 220, cutting board; 230, main guide block; 240, limiting groove; 250, guide groove; 260, U-shaped positioning frame; 270, telescopic rod; 280, spring; 300, lower collection assembly; 310, triangular collection assembly; 320, rotating plate; 330, rotating assembly; 331, left connecting block; 332, left connecting arm; 333, right connecting block; 334, right connecting arm; 335, positioning shaft; 400, collection assembly; 410, mounting shaft; 420, extension rod; 430, connecting plate; 440, fixing rod; 450, collection frame. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0025] Please see Figure 1-6An NGS sample collector includes a collector assembly 100, a lifting sampling assembly 200, a lower collection assembly 300, and a collection assembly 400. The collector assembly 100 includes a housing 110, a handle 120 mounted on the outer wall of the housing 110, a cover plate 130 on the top of the housing 110, a positioning groove 140 mounted on the bottom of the cover plate 130, a guide plate 150 on the inner wall of the housing 110, and a positioning post 160 on the inner wall of the housing 110. The guide plate 150 and the positioning post 160, located within the housing 110, guide the main guide block 230 during lifting and lowering. The lifting sampling assembly 200 includes a main guide block 230 disposed on the inner wall of the housing 110, with a handle 120 mounted on the top of the main guide block 230. A connecting rod 210 has a cutting board 220 mounted on the side away from the main guide block 230. A limiting groove 240 and a guide groove 250 are provided on the outer wall of the main guide block 230. A telescopic rod 270 is provided on the inner wall of the limiting groove 240. A U-shaped positioning frame 260 is mounted on the outer wall of the telescopic rod 270. A spring 280 is sleeved on the outer wall of the telescopic rod 270. When the main guide block 230 descends, the positioning post 160 contacts the U-shaped positioning frame 260, and the spring 280 is compressed. After collection, the main guide block 230 is reset. The lower collection assembly 300 includes a triangular collection assembly 310 disposed on the outer wall of the main guide block 230. A rotating plate 320 is provided on the outer wall of the triangular collection assembly 310. A rotating assembly 330 is installed on the inner wall of the rotating plate 320. The rotating assembly 330 includes a left connecting block 331 disposed on the outer wall of the rotating plate 320. A left connecting arm 332 is installed on the outer wall of the left connecting block 331. A right connecting block 333 is installed on the side of the rotating plate 320 away from the left connecting block 331. A right connecting arm 334 is installed on the outer wall of the right connecting block 333. A positioning shaft 335 is provided on the outer wall of the right connecting arm 334. The acquisition assembly 400 includes a mounting shaft 410 disposed on the outer wall of the main guide block 230. An extension rod 420 is installed on the side of the mounting shaft 410 away from the main guide block 230. A connecting plate 430 is installed on the side of the extension rod 420 away from the mounting shaft 410. A fixing rod 440 is provided on the outer wall of the connecting plate 430. The wall is equipped with a collection frame 450, in which the connecting plate 430, fixing rod 440, and collection frame 450 are integrated. The collection frame 450 has a conical groove, which allows it to collect the drug after contacting the sample. The guide plate 150 and positioning post 160 are symmetrically distributed on the inner wall of the housing 110, and the guide plate 150 is slidably connected to the main guide block 230. The extension rod 420 and connecting plate 430 are integrated, and multiple fixing rods 440 are distributed in a circumferential array on the outer wall of the connecting plate 430. The positioning shaft 335 passes through the left connecting arm 332 and the right connecting arm 334, and the left connecting arm 332 and the right connecting arm 334 are rotatably connected.This design allows for the limiting of the left connecting arm 332 and the right connecting arm 334 during operation. The rotating plate 320 is symmetrically distributed on the outer wall of the triangular collecting assembly 310, and is rotatably connected to the triangular collecting assembly 310. The limiting groove 240 is sleeved with the positioning post 160, and is also slidably connected to it. This ensures that when the main guide block 230 slides inside the housing 110, the guide plate 150 and the positioning post 160 can limit the movement of the main guide block 230, effectively preventing positional displacement of the main guide block 230 during movement.

[0026] Working principle: When the device is needed, the worker holds the handle 120 and moves it to a suitable position, then presses down the cutting board 220, causing the triangular collection component 310 to move downward. After the triangular collection component 310 moves downward, the rotating plate 320 opens, and the sample is collected through the collection rack 450 inside the triangular collection component 310.

[0027] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. An NGS test sample collector, characterized in that, It comprises a collector assembly (100), a lifting sampling assembly (200), a lower collection assembly (300) and a collection assembly (400), The collector assembly (100) comprises a shell (110), the outer wall of the shell (110) is provided with a handle (120), the top of the shell (110) is provided with a cover plate (130), the bottom of the cover plate (130) is provided with a positioning groove (140), the inner wall of the shell (110) is provided with a guide plate (150), and the inner wall of the shell (110) is provided with a positioning column (160). The lifting sampling assembly (200) comprises a main guide block (230) arranged on the inner wall of the shell (110), the top of the main guide block (230) is provided with a connecting rod (210), the side away from the main guide block (230) of the connecting rod (210) is provided with a case plate (220), the outer wall of the main guide block (230) is provided with a limiting groove (240), the outer wall of the main guide block (230) is provided with a guide groove (250), the inner wall of the limiting groove (240) is provided with a telescopic rod (270), the outer wall of the telescopic rod (270) is provided with a U-shaped positioning frame (260), and the outer wall of the telescopic rod (270) is sleeved with a spring (280). The lower collection assembly (300) comprises a triangular collection assembly (310) arranged on the outer wall of the main guide block (230), and the outer wall of the triangular collection assembly (310) is provided with a rotating plate (320). The rotating assembly (330) comprises a left connecting block (331) arranged on the outer wall of the rotating plate (320), the outer wall of the left connecting block (331) is provided with a left connecting arm (332), the side away from the left connecting block (331) of the rotating plate (320) is provided with a right connecting block (333), the outer wall of the right connecting block (333) is provided with a right connecting arm (334), and the outer wall of the right connecting arm (334) is provided with a positioning shaft (335). The collection assembly (400) comprises a mounting shaft (410) arranged on the outer wall of the main guide block (230), the side away from the main guide block (230) of the mounting shaft (410) is provided with an extension rod (420), the side away from the mounting shaft (410) of the extension rod (420) is provided with a connecting disc (430), the outer wall of the connecting disc (430) is provided with a fixing rod (440), and the outer wall of the fixing rod (440) is provided with a collection frame (450).

2. The NGS test sample collector of claim 1, wherein: The guide plate (150) and the positioning column (160) are symmetrically arranged on the inner wall of the shell (110), and the guide plate (150) and the main guide block (230) are in sliding connection.

3. The NGS test sample collector of claim 1, wherein: The extension rod (420) and the connecting disc (430) are integrated devices, and a plurality of fixing rods (440) are arranged in a circumferential array on the outer wall of the connecting disc (430).

4. The NGS test sample collector of claim 1, wherein: The positioning shaft (335) penetrates the left connecting arm (332) and the right connecting arm (334), and the left connecting arm (332) and the right connecting arm (334) are in rotary connection.

5. The NGS test sample collector of claim 1, wherein: The rotating plates (320) are symmetrically arranged on the outer wall of the triangular collecting assembly (310), and the rotating plates (320) are rotationally connected with the triangular collecting assembly (310).

6. The NGS test sample collector of claim 1, wherein: The limiting grooves (240) are sleeved with the positioning columns (160), and the limiting grooves (240) and the positioning columns (160) are slidingly connected.