Drug balloon dilatation catheter
By designing an interlaced braided wire support and drug delivery port on the balloon dilation catheter, the problems of restenosis after dilation and poor drug delivery were solved, achieving the effects of active drug delivery and rapid drug absorption.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-21
- Publication Date
- 2026-03-24
AI Technical Summary
Existing balloon dilation catheters are prone to restenosis after dilation and have poor drug delivery effects, especially radial perforation catheters that affect the balloon structure or are blocked by the blood vessel wall, leading to drug delivery failure.
A drug delivery balloon dilation catheter was designed, comprising a balloon, a stent made of multiple interwoven braided filaments, and a delivery system. By setting a drug delivery port on the side of the braided filaments away from the balloon, the knots at the intersections of the braided filaments are used to press against the blood vessel wall, forming a drug delivery space when the balloon dilates, thus achieving active drug delivery.
This allows for effective drug delivery during balloon dilation, improving the drug's efficacy and ensuring that the medication can directly target the stenotic lesion and be rapidly absorbed.
Smart Images
Figure CN224024038U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to medical instrument technical field, especially relate to a active dosing formula medicine balloon dilatation catheter of good dosing effect. BACKGROUND
[0002] For the patient of vascular stenosis, the common treatment means currently is percutaneous transluminal angioplasty, and the instrument used in percutaneous transluminal angioplasty is balloon dilatation catheter, which is used to expand the narrow blood vessel, and the traditional balloon dilatation catheter has problems such as difficult to expand the stenosis and restenosis after expansion.
[0003] In order to solve the problem of restenosis after expansion, a drug balloon dilatation catheter is invented, and most of these balloon dilatation catheters give medicine by impregnating medicine on the outer wall of the balloon or by hanging a micro drug capsule, and the medicine effect depends on the dissolution degree of the drug capsule in the blood, which belongs to passive drug delivery, and some balloon dilatation catheters have radial through pipes on the balloon, and the medicine is directly injected through the radial through pipes, which can actively give medicine, but the radial through pipes will affect the overall structure of the balloon, and the outlet of the radial through pipe is easy to be blocked by the blood vessel wall during balloon expansion, resulting in failure of drug delivery. SUMMARY
[0004] The utility model aims at overcoming the shortcomings in the prior art, and provides a drug balloon dilatation catheter.
[0005] To achieve the above-mentioned purpose, the utility model adopts the technical scheme of a drug balloon dilatation catheter, which comprises:
[0006] a balloon;
[0007] a stent, which is covered on the surface of the balloon and is composed of a plurality of interlaced braided wires;
[0008] a delivery system, which is used to deliver the balloon and the stent to the stenosis and give medicine, and comprises an inner tube, an intermediate tube and an outer tube arranged from inside to outside;
[0009] The intermediate tube and the outer tube form a medicine liquid cavity, one end of the stent is hot-melted between the intermediate tube and the outer tube, and the other end is covered on the tip portion of the balloon, the braided wire is hollow inside to form a medicine delivery cavity in communication with the medicine liquid cavity, a plurality of medicine delivery holes are arranged on the side of the braided wire away from the balloon and spaced along the extending direction of the braided wire, the medicine delivery holes are in communication with the medicine delivery cavity, the nodes at the intersections of the braided wires protrude from the surface of the stent, when the balloon is expanded, the nodes abut against the blood vessel wall at the stenosis lesion to form a medicine delivery space between the single braided wire and the blood vessel wall, and the medicine liquid flowing from the medicine liquid cavity can be released to the medicine delivery space through the medicine delivery cavity and the medicine delivery holes.
[0010] Preferably, the cross-sectional shape of the braided wire is trapezoidal, the side of the braided wire in contact with the balloon is the long side of the trapezoid, and the side of the braided wire away from the balloon is the short side of the trapezoid, and the medicine delivery holes are arranged on the short side.
[0011] Further preferably, the length of the long side is 0.1mm-10mm, the length of the short side is 0.05mm-5mm, and the height of the trapezoid is 0.15mm-10mm.
[0012] Further preferably, the length of the long side is 0.7mm-3mm, the length of the short side is 0.5mm-1mm, and the height of the trapezoid is 0.2mm-2mm.
[0013] Preferably, the diameter of the medicine delivery hole is 0.05mm-1mm.
[0014] Further preferably, the diameter of the medicine delivery hole is 0.1mm-0.5mm.
[0015] Preferably, the braided wire is spirally wound on the surface of the balloon, when the balloon is not expanded, the braided wire is in s shape, and when the balloon is expanded, the braided wire is transformed from s shape to straight line shape to provide necessary deformation amount.
[0016] Further preferably, after the balloon is completely depressurized, the braided wire returns to s shape.
[0017] Preferably, the braided wire has at least three wires, and the number of nodes is not less than 12.
[0018] Preferably, the end portion of the inner tube protruding from the balloon is wrapped with a tip tube, and the tip tube is used to fold and block the tip portion of the inner tube, the balloon and the end portion of the stent.
[0019] Thanks to the above technical scheme, the present application has the following advantages compared with the prior art:
[0020] The drug balloon dilatation catheter provided by the utility model, comprising a balloon, a stent covered on the surface of the balloon and formed by interlaced weaving of a plurality of braided wires, a conveying system for conveying the balloon and the stent to a stenosis lesion and performing drug delivery, the conveying system comprising an inner tube, an intermediate tube and an outer tube, a drug liquid cavity is formed between the intermediate tube and the outer tube, one end of the stent is hot-melted between the intermediate tube and the outer tube, the other end is covered on the tip portion of the balloon, the braided wire is hollow, a drug delivery cavity is formed in communication with the drug liquid cavity, a plurality of drug delivery holes are arranged on the side of the braided wire away from the balloon, the drug delivery holes are distributed along the extension direction of the braided wire and are in communication with the drug delivery cavity, the nodes at the interlaced positions of the braided wire protrude from the surface of the stent, when the balloon is dilated, the nodes can abut against the blood vessel wall of the stenosis lesion, thereby forming a drug delivery space between the single braided wire and the blood vessel wall, the drug liquid flowing from the drug liquid cavity can be released to the drug delivery space through the drug delivery cavity and the drug delivery holes, active drug delivery is realized, and the drug delivery effect is good. BRIEF DESCRIPTION OF DRAWINGS
[0021] Figure 1 is the front view schematic diagram of the preferred embodiment of the utility model.
[0022] Figure 2 is Figure 1 the local enlarged schematic diagram of the single braided wire in the intermediate tube.
[0023] Figure 3 is Figure 2 the sectional view schematic diagram of the A-A direction in the intermediate tube.
[0024] Wherein: 10. balloon; 20. stent; 21. braided wire; 22. node; 30. conveying system; 31. inner tube; 311. guide wire cavity; 32. intermediate tube; 321. filling cavity; 33. outer tube; 34. tip tube; 41. drug liquid cavity; 42. drug delivery cavity; 43. drug delivery hole; 51. developing ring; 52. catheter seat. DETAILED DESCRIPTION
[0025] As Figures 1 to 3As shown, the utility model provides a drug balloon dilatation catheter, including balloon 10, support 20, conveying system 30, wherein, balloon 10 plays the role of dilating support, balloon 10 burst pressure is at least 8atm, in this embodiment, the material of balloon 10 is nylon 12, the burst pressure of balloon 10 is 12atm, support 20 is covered on the surface of balloon 10, support 20 is formed by the interlaced weaving of multiple braided filaments 21, conveying system 30 is used to convey balloon 10 and support 20 to narrow lesion and carries out administration, conveying system 30 includes the inner tube 31, intermediate tube 32 and outer tube 33 that are coaxially arranged in turn from inside to outside, the cavity in the inner tube 31 constitutes the guide wire cavity 311, the cavity between the inner tube 31 and intermediate tube 32 constitutes the filling cavity 321, and the intermediate tube 32 and outer tube 33 constitute the liquid chamber 41, one end of support 20 is hot melt between the intermediate tube 32 and outer tube 33, and the other end is covered in the tip portion of balloon 10, the braided filament 21 is hollow inside, forms the medicine delivery cavity 42 that communicates with the liquid chamber 41, the side of braided filament 21 away from balloon 10 is equipped with multiple administration holes 43 that are spaced apart along its extension direction, the administration hole 43 is communicated with the medicine delivery cavity 42, and the node 22 at the interlaced place of braided filament 21 protrudes from the surface (the surface where single-layer braided filament 21 is located) of support 20, when balloon 10 expands, the node 22 is tightly pressed against the blood vessel wall of narrow lesion, forms the administration space between single braided filament 21 and the blood vessel wall, makes the drug solution flowing from the liquid chamber 41 be released to the administration space through the medicine delivery cavity 42 and administration hole 43, realizes active administration, since balloon 10 is in the expanded state when administering, will prevent part of blood flow, makes the blood vessel wall of narrow lesion be in the higher drug solution concentration, thereby rapidly absorbing effective component, and the administration effect is good.
[0026] The cross-sectional shape of the braided filament 21 is trapezoidal, one side of the braided filament 21 in contact with the balloon 10 is the long side of the trapezoid, the other side of the braided filament 21 away from the balloon 10 is the short side of the trapezoid, the administration hole 43 is arranged on the short side, preferably, the length of the long side of the trapezoid is 0.1mm-10mm, the length of the short side of the trapezoid is 0.05mm-5mm, the height of the trapezoid is 0.15mm-10mm, further preferably, the length of the long side of the trapezoid is 0.7mm-3mm, the length of the short side of the trapezoid is 0.5mm-1mm, the height of the trapezoid is 0.2mm-2mm, specifically to this embodiment, the length of the long side of the trapezoid is 1.4mm, the length of the short side of the trapezoid is 0.7mm, and the height of the trapezoid is 0.5mm, the diameter of the administration hole is preferably 0.05mm-1mm, further preferably, the diameter of the administration hole is 0.1mm-0.5mm, specifically to this embodiment, the diameter of the administration hole is 0.1mm.
[0027] Preferably, the braided wire 21 has at least three wires, and the number of the knots 22 is not less than 12, and in the embodiment, the braided wire 21 has three wires, and the number of the knots 22 is 12, and the braided wire 21 is made of a nickel-titanium material through a drawing process, and during the drawing, a trapezoidal tool is used, and the drug delivery hole 43 is made through a laser drilling process.
[0028] In the embodiment, the braided wire 21 is spirally wound on the surface of the balloon 10, and when the balloon 10 is not expanded, the braided wire 21 is in an s shape, and the diameter of each semicircle of the s shape is 5-8 mm, and when the balloon 10 is expanded, the braided wire 21 is transformed from the s shape to a straight line shape to provide a necessary deformation amount, and meanwhile, after the balloon 10 is completely depressurized, the braided wire 21 returns to the s shape, and during the manufacture of the stent, since the braided wire 21 has a certain softness due to the thin diameter, the single braided wire 21 can be only spirally wound on the balloon 10 and then staggered and attached, and does not need to be folded, and the staggered braiding effect of the long side of the braided wire 21 facing inward and the short side facing outward can be achieved.
[0029] In the embodiment, the part of the end of the inner tube 31 extending out of the balloon 10 is wrapped with a tip tube 34, and the tip tube 34 is used to gather the tip part of the balloon 10, the inner tube 31 and the end of the stent 20.
[0030] During use, firstly, the balloon 10 is expanded through the inflation cavity 321, the balloon 10 drives the stent 20 to expand, and the stenosis lesion is expanded to a normal shape, and then, the expansion pressure is slightly reduced, the knots 22 are in contact with the blood vessel wall, and the single braided wire 21 is out of contact with the blood vessel wall, and a drug delivery space is formed between the single braided wire 21 and the blood vessel wall, at this time, the drug liquid required in the clinic is injected through the drug liquid cavity 41, and the drug liquid is delivered to the drug delivery space through the drug liquid cavity 41→the drug delivery cavity 42→the drug delivery hole 43, since the balloon 10 is still in the expanded state, part of the blood flow is blocked, the blood vessel wall at the stenosis lesion is in a relatively high drug liquid concentration, and thus the effective component is quickly absorbed.
[0031] It should be noted that the drug balloon dilatation catheter provided by the utility model must include a developing ring 51 and a catheter seat 52, the developing ring 51 is arranged on the inner tube 31 located in the balloon 10, and the catheter seat 52 is arranged at the end of the delivery system 30 away from the balloon 10 and located outside the body.
[0032] The above embodiment is only for describing the technical concept and characteristics of the utility model, and the purpose is to enable the person skilled in the art to understand the content of the utility model and implement it, and cannot limit the protection scope of the utility model. Any equivalent change or modification according to the spirit and essence of the utility model should be covered in the protection scope of the utility model.
Claims
1. A drug balloon dilatation catheter, comprising: a balloon; a stent, which is covered on the surface of the balloon, the stent being interlaced woven by a plurality of woven wires; a delivery system, which is used to deliver the balloon and the stent to a stenosis lesion and to administer drugs, the delivery system comprising, from inside to outside, an inner tube, an intermediate tube and an outer tube; characterized in that: a drug liquid cavity is formed between the intermediate tube and the outer tube, one end of the stent is heat-fused between the intermediate tube and the outer tube, and the other end is covered on the tip portion of the balloon, the woven wire is hollow inside to form a drug delivery cavity in communication with the drug liquid cavity, a plurality of drug administration holes are arranged on the side of the woven wire away from the balloon and spaced along the extension direction of the woven wire, the drug administration holes are in communication with the drug delivery cavity, and the nodes at the interlaced portions of the woven wire protrude from the surface of the stent, when the balloon is dilated, the nodes abut against the vessel wall of the stenosis lesion to form a drug administration space between a single woven wire and the vessel wall, so that the drug liquid flowing from the drug liquid cavity can be released to the drug administration space through the drug delivery cavity and the drug administration holes.
2. The drug balloon dilation catheter of claim 1, wherein: The cross-sectional shape of the woven wire is trapezoidal, the side of the woven wire in contact with the balloon is the long side of the trapezoid, and the side of the woven wire away from the balloon is the short side of the trapezoid, and the drug administration holes are arranged on the short side.
3. The drug balloon dilation catheter of claim 2, wherein: The length of the long side is 0.1-10 mm, the length of the short side is 0.05-5 mm, and the height of the trapezoid is 0.15-10 mm.
4. The drug balloon dilation catheter of claim 3, wherein: The length of the long side is 0.7-3 mm, the length of the short side is 0.5-1 mm, and the height of the trapezoid is 0.2-2 mm.
5. The drug balloon dilation catheter of claim 1, wherein: The diameter of the drug administration hole is 0.05-1 mm.
6. The drug balloon dilation catheter of claim 5, wherein: The diameter of the drug administration hole is 0.1-0.5 mm.
7. The drug balloon dilation catheter of claim 1, wherein: The woven wire is spirally wound on the surface of the balloon, when the balloon is not dilated, the woven wire is in an s shape, and when the balloon is dilated, the woven wire changes from an s shape to a straight line to provide a necessary deformation amount.
8. The drug balloon dilation catheter of claim 7, wherein: After the balloon is completely depressurized, the woven wire returns to an s shape.
9. The drug balloon dilation catheter of claim 1, wherein: The woven wire has at least three wires, and the number of nodes is not less than 12.
10. The drug balloon dilation catheter of claim 1, wherein: The portion of the end of the inner tube protruding from the balloon is wrapped with a tip tube, and the tip tube is used to fold and block the tip portion of the inner tube, the balloon and the end of the stent.