Liquid chromatograph with automatic sample injection correction device

Abstract

The utility model relates to the technical field of liquid chromatographs, and discloses a liquid chromatograph with an automatic sample injection correction device, which comprises a machine body, a controller arranged on the machine body, a shell fixedly mounted on the outer wall of one side of the machine body, and a metering pump fixedly mounted on the inner wall of one side, close to the machine body, in the shell, the outer wall of one side of the metering pump away from the machine body is fixedly connected with a sampling pipe. According to the utility model, the correction block is matched with the correction groove, so that the sampling process of a sample in a test tube by the sample injection tube can be corrected, and the influence on normal sampling of the sample caused by deviation of the sample injection tube in the sampling process is avoided; a second servo motor in the lifting assembly is matched with a receiver fixedly mounted on the second servo motor through an emitter fixedly mounted on a sample introduction disc to trigger the second servo motor to start, and a sample introduction pipe and a test tube in a placement groove can be subjected to secondary correction in the matching process of the emitter and the receiver; and the tail end of the sample introduction tube can accurately extend into the test tube for sampling.

Description

Technical Field

[0001] This utility model relates to the field of liquid chromatography technology, and in particular to a liquid chromatograph with an automatic sample injection correction device. Background Technology

[0002] Liquid chromatography (LC) is an important tool in modern analytical chemistry, and its core function is to efficiently separate and accurately detect complex samples. Among its components, the automated sampler is a key module for achieving high-throughput analysis, significantly improving detection efficiency and reducing human error.

[0003] Traditional automated samplers typically use mechanical transmission to rotate the sample tray and use injection needles to sequentially extract different samples. However, in practical applications, long-term operation of the mechanical structure can lead to cumulative errors, or positioning misalignment due to differences in sample container dimensions. This can result in misalignment between the injection needle and the sample vial, affecting sampling accuracy or even causing needle damage or sample contamination, severely limiting the reliability of the test results. Furthermore, existing technologies often rely on preset programs to control the rotation angle, lacking real-time feedback and dynamic correction mechanisms. When mechanical errors exceed the tolerance, timely feedback cannot be obtained. To address these issues, we propose a liquid chromatograph with an automatic injection correction device. Utility Model Content

[0004] The present invention aims to solve the technical problems existing in the prior art and provide a liquid chromatograph with an automatic sample injection correction device.

[0005] To achieve the above objectives, the present invention adopts the following technical solution: a liquid chromatograph with an automatic injection calibration device, comprising a body, a controller mounted on the body, an outer shell fixedly mounted on one side of the body, a metering pump fixedly mounted on the inner wall of the outer shell near the body, an injection tube fixedly connected to the outer wall of the metering pump away from the body, the injection tube consisting of a pipe and a sampling needle at the end of the pipe, a delivery pipe fixedly connected to the side wall of the metering pump, which is connected to the injection port on the body, an automatic injection assembly located at the lower end of the injection tube inside the outer shell, the automatic injection assembly including a rotatable injection disc, an extension cover fixedly mounted on the outer wall of the outer shell corresponding to the injection disc, a movable door rotatably mounted on the extension cover, a calibration groove formed on the upper surface of the injection disc, a fixing plate for supporting the automatic injection assembly on the bottom surface of the outer shell, a lifting assembly below the fixing plate, an electric telescopic rod fixedly mounted on the top inner wall of the outer shell, and a calibration block for cooperating with the calibration groove fixedly mounted on the lower end of the electric telescopic rod.

[0006] Preferably, the automatic sample feeding assembly further includes a first servo motor fixedly mounted on the upper surface of the fixed plate, the sample feeding disk being fixedly connected to the output end of the first servo motor, and a plurality of placement slots being provided through the upper surface of the sample feeding disk, each of the plurality of placement slots being provided with a clamping structure.

[0007] Preferably, the lifting assembly includes two fixed brackets fixedly installed on the inner wall of the bottom surface of the housing, a cam rotatably installed between the two fixed brackets, the outer wall of the cam contacting the bottom surface of the fixed plate, and a second servo motor fixedly installed on the bottom surface of the housing at the position corresponding to the cam, the output end of the second servo motor being fixedly connected to the outer wall of the cam.

[0008] Preferably, spring support legs are fixedly installed at the four corners of the bottom surface of the fixing plate, and the ends of the spring support legs are fixedly connected to the inner wall of the bottom surface of the outer shell.

[0009] Preferably, the clamping structure includes a limiting rod that is slidably connected to the sample injection plate. A clamping block is fixedly installed at the end of the limiting rod. A spring is fixedly connected to the outer wall of the clamping block near the sample injection plate. The spring is located outside the limiting rod and the other end of the spring is fixedly connected to the inner wall of the sample injection plate.

[0010] Preferably, transmitters are fixedly installed on the outer wall of the sample inlet plate at corresponding positions of the multiple placement slots, and receivers for use with the transmitters are fixedly installed on the second servo motor, with the receivers electrically connected to the second servo motor.

[0011] Preferably, a support tray is also fixedly installed on the outer wall of the output end of the first servo motor below the sample inlet plate.

[0012] Beneficial effects

[0013] This invention provides a liquid chromatograph with an automatic sample injection correction device. It has the following features:

[0014] Beneficial effects:

[0015] This liquid chromatograph with an automatic injection calibration device can calibrate the process of the injection tube taking samples from the inside of the test tube by cooperating with the calibration block and calibration tank. This avoids deviations in the injection tube during the sampling process that may affect the normal sampling. In addition, the second servo motor in the lifting component is triggered by a transmitter fixedly installed on the injection plate and a receiver fixedly installed on the second servo motor. During the process of the transmitter and receiver cooperating, the injection tube and the test tube in the placement tank can be calibrated a second time to ensure that the end of the injection tube can accurately extend into the inside of the test tube for sampling. Attached Figure Description

[0016] To more clearly illustrate the embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings in the following description are merely exemplary, and those skilled in the art can derive other embodiments based on the provided drawings without creative effort.

[0017] The structures, proportions, sizes, etc. illustrated in this specification are only for the purpose of assisting those skilled in the art in understanding and reading the content disclosed herein, and are not intended to limit the implementation conditions of this utility model. Therefore, they have no substantial technical significance. Any modifications to the structure, changes in the proportions, or adjustments to the size, without affecting the effects and objectives that this utility model can produce, should still fall within the scope of the technical content disclosed in this utility model.

[0018] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0019] Figure 2 This is a schematic diagram of the interior of the outer shell of this utility model;

[0020] Figure 3 This is a schematic diagram of the sample inlet disk structure of this utility model;

[0021] Figure 4 This is a schematic diagram of the clamping structure of this utility model;

[0022] Figure 5 This utility model Figure 3 Enlarged structural diagram at point A in the middle.

[0023] Legend: 1. Body; 2. Outer shell; 3. Extension cover; 4. Movable door; 5. Sample inlet tray; 6. Controller; 7. Support tray; 8. First servo motor; 9. Fixing plate; 10. Spring support leg; 11. Electric telescopic rod; 12. Calibration block; 13. Delivery pipe; 14. Metering pump; 15. Sample inlet tube; 16. Second servo motor; 17. Cam; 18. Fixing frame; 19. Calibration groove; 20. Transmitter; 21. Clamping block; 22. Limiting rod; 23. Spring; 24. Receiver. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0025] like Figure 1-5 As shown, a liquid chromatograph with an automatic sample injection calibration device includes a body 1, which is the main body of the liquid chromatograph. Samples can be analyzed by inputting them into the body 1; this is prior art and will not be described in detail here. A controller 6 is installed on the body 1. A housing 2 is fixedly installed on one side of the outer wall of the body 1. A metering pump 14 is fixedly installed on the inner wall of the housing 2 near the body 1. An injection tube 15 is fixedly connected to the outer wall of the metering pump 14 away from the body 1. The injection tube 15 consists of a pipe and a sampling needle at the end of the pipe. A delivery tube 13 is fixedly connected to the side wall of the metering pump 14. The sample inlet on the body 1 is connected to the delivery pipe 13. An automatic sample feeding assembly is located inside the outer shell 2 at the lower end of the sample feeding pipe 15. The automatic sample feeding assembly includes a rotatable sample feeding disc 5. An extension cover 3 is fixedly installed on the outer wall of the outer shell 2 at a position corresponding to the sample feeding disc 5. A movable door 4 is rotatably installed on the extension cover 3. A calibration groove 19 is opened on the upper surface of the sample feeding disc 5. A fixing plate 9 for supporting the automatic sample feeding assembly is provided on the bottom surface of the outer shell 2, and a lifting assembly is provided below the fixing plate 9. An electric telescopic rod 11 is fixedly installed on the inner top wall of the outer shell 2. The lower end of the electric telescopic rod 11 is fixedly installed with the calibration groove. The calibration block 12 is used in conjunction with the sample inlet plate 5. Multiple placement slots are provided on the sample inlet plate 5, each containing a test tube filled with a sample. The lifting assembly can raise the fixing plate 9 and the automatic sample inlet assembly as a whole, allowing the sampling needle at the end of the sample inlet tube 15 to insert into the test tube for sampling. After the sample inlet plate 5 rotates the test tube to be sampled to directly below the sample inlet tube 15, the calibration block 12 is moved downwards by extending the electric telescopic rod 11. A pressure sensor is installed inside the calibration slot 19. The calibration block 12, positioned directly above the sample inlet plate 5, engages with the calibration slot 19 and compresses it. If the pressure sensor inside plate 9 indicates that the test tube in the placement slot is directly below the injection tube 15, the injection plate 5 can be raised by the lifting component to successfully sample through the injection tube 15. Conversely, if the pressure sensor inside plate 9 indicates that the test tube placed on the injection plate 5 is not in the correct position from the sampling position of the injection tube 15, the first servo motor 8 needs to be driven to rotate the injection plate 5 to correct its position before the lifting component can be used to raise the fixing plate 9 and the automatic injection component together. Then, the injection tube 15 can be inserted into the test tube to sample. The shape of the correction slot 19 is determined by the number of placement slots opened on the injection plate 5.

[0026] like Figure 2As shown, the automatic sample feeding assembly also includes a first servo motor 8 fixedly mounted on the upper surface of the fixing plate 9. The sample feeding disk 5 is fixedly connected to the output end of the first servo motor 8. Multiple placement slots are opened through the upper surface of the sample feeding disk 5, and clamping structures are provided inside the multiple placement slots. The first servo motor 8 can drive the sample feeding disk 5 to rotate. The angle of rotation of the sample feeding disk 5 in a single rotation is related to the number of placement slots opened on the sample feeding disk 5. The multiple placement slots opened on the sample feeding disk 5 are equidistantly distributed. The first servo motor 8 drives the sample feeding disk 5 to rotate once, which can rotate the adjacent placement slot to below the sample feeding tube 15. The clamping structure can clamp and fix the test tube placed inside the placement slot.

[0027] like Figure 2 As shown, the lifting assembly includes two fixed brackets 18 fixedly installed on the inner wall of the bottom surface of the housing 2. A cam 17 is rotatably installed between the two fixed brackets 18. The outer wall of the cam 17 contacts the bottom surface of the fixed plate 9. A second servo motor 16 is also fixedly installed on the bottom surface of the housing 2 at the corresponding position of the cam 17. The output end of the second servo motor 16 is fixedly connected to the outer wall of the cam 17. The cam 17 is driven to rotate by the second servo motor 16. The outer wall of the cam 17 is always in contact with the bottom surface of the fixed plate 9. Therefore, when the cam 17 rotates one revolution, the fixed plate 9 and the automatic sample feeding assembly fixedly installed on the fixed plate 9 can be lifted upward once.

[0028] like Figure 2 As shown, spring support legs 10 are fixedly installed at the four corners of the bottom surface of the fixed plate 9, and the ends of the spring support legs 10 are fixedly connected to the inner wall of the bottom surface of the outer shell 2. The spring support legs 10 are legs that achieve elastic extension and retraction through the built-in spring 23. The four spring support legs 10 can support the four corners of the bottom surface of the fixed plate 9.

[0029] like Figure 4 As shown, the clamping structure includes a limiting rod 22 that is slidably connected to the sample inlet plate 5. A clamping block 21 is fixedly installed at the end of the limiting rod 22. A spring 23 is fixedly connected to the outer wall of the clamping block 21 near the sample inlet plate 5. The spring 23 is located outside the limiting rod 22 and the other end of the spring 23 is fixedly connected to the inner wall of the sample inlet plate 5. A chamfer is provided at the upper end of the clamping block 21. When test tubes of different diameters are placed in the placement slot, the outer wall of the test tube squeezes the clamping block 21, which causes the spring 23 to deform and contract. The limiting rod 22 can also contract into the sample inlet plate 5. Thus, the clamping structure can clamp test tubes of different diameters.

[0030] like Figure 5As shown, transmitters 20 are fixedly installed on the outer wall of the sample inlet plate 5 and at corresponding positions of multiple placement slots. A receiver 24 for use with the transmitter 20 is fixedly installed on the second servo motor 16. The receiver 24 is electrically connected to the second servo motor 16. When any transmitter 20 rotates to be directly above the receiver 24, the laser signal emitted by the transmitter 20 is received by the receiver 24. Then the second servo motor 16 can start to drive the cam 17 to rotate one revolution, and the fixed plate 9 is raised by the cam 17. The transmitter 20 and the receiver 24 are aligned by laser. The transmitter 20 can be a Lumentum HL63193DG, and the receiver 24 can be a First Sensor APD440A.

[0031] like Figure 2 As shown, a support tray 7 is fixedly installed on the outer wall of the output end of the first servo motor 8 below the sample inlet plate 5. When the test tube is placed inside the placement slot, the bottom of the test tube can be supported by the support tray 7.

[0032] The working principle of this utility model is as follows: During use, the user places different samples into the placement slots on the sample inlet tray 5. The clamping structure in the placement slots can hold test tubes of different diameters. Then, under the action of the first servo motor 8, the sample inlet tray 5 is driven to rotate. The angle of rotation of the sample inlet tray 5 in a single rotation is related to the number of placement slots on the sample inlet tray 5. Each rotation of the sample inlet tray 5 removes the test tube located below the sample inlet tube 15 and moves the test tube in the adjacent placement slot below the sample inlet tube 15 for automatic sampling. When the test tube is moved below the sample inlet tube 15, the transmitter 20, which is fixedly installed on the outer wall of the sample inlet tray 5 and corresponds to the placement slot, moves to directly above the receiver 24. At this time, the second servo motor 16 drives the cam 17 to rotate, which can raise the fixing plate 9 and the automatic sampling assembly as a whole, thereby allowing the sampling needle at the end of the sample inlet tube 15 to extend into the test tube for sampling. The sample inlet tray 5 rotates to rotate the test tube to be sampled. After moving to directly below the injection tube 15, the calibration block 12 is moved downward by extending the electric telescopic rod 11. If the calibration block 12, located directly above the injection plate 5, is engaged with the inside of the calibration groove 19 and squeezes the pressure sensor inside the calibration groove 19, it indicates that the test tube in the groove is directly below the injection tube 15. At this time, the injection plate 5 can be raised upward by the lifting component and the sample can be easily taken through the injection tube 15. Otherwise, it indicates that there is a deviation between the sample tube placed on the injection plate 5 and the sampling position of the injection tube 15. It is necessary to drive the first servo motor 8 to drive the injection plate 5 to rotate and correct the position of the injection plate 5 before the transmitter 20 and receiver 24 can trigger the lifting component to raise the fixing plate 9 and the automatic injection component as a whole. Then, the sample is inserted into the test tube through the injection tube 15 for sampling. Under the action of the metering pump 14, the injection tube 15 quantitatively samples, and then the sample is input into the body 1 for analysis through the delivery tube 13.

[0033] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claims. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A liquid chromatograph with an automatic sample injection calibration device, comprising a body (1), a controller (6) mounted on the body (1), and a housing (2) fixedly mounted on one side of the outer wall of the body (1), characterized in that: A metering pump (14) is fixedly installed on the inner wall of the outer casing (2) near the machine body (1). An inlet tube (15) is fixedly connected to the outer wall of the metering pump (14) away from the machine body (1). The inlet tube (15) consists of a pipe and a sampling needle at the end of the pipe. A delivery tube (13) is fixedly connected to the side wall of the metering pump (14). The delivery tube (13) connects to the inlet on the machine body (1). An automatic sampling assembly is installed inside the outer casing (2) at the lower end of the inlet tube (15). The automatic sampling assembly includes a rotatable sampling disc. (5) An extension cover (3) is fixedly installed on the outer wall of the outer shell (2) at the corresponding position of the injection plate (5). An movable door (4) is rotatably installed on the extension cover (3). A calibration groove (19) is opened on the upper surface of the injection plate (5). A fixing plate (9) for supporting the automatic injection component is provided on the bottom surface of the outer shell (2). A lifting component is provided below the fixing plate (9). An electric telescopic rod (11) is fixedly installed on the top inner wall of the outer shell (2). A calibration block (12) that works with the calibration groove (19) is fixedly installed at the lower end of the electric telescopic rod (11).

2. A liquid chromatograph with an automatic sample injection calibration device according to claim 1, characterized in that: The automatic sample feeding assembly also includes a first servo motor (8) fixedly installed on the upper surface of the fixing plate (9), the sample feeding disk (5) is fixedly connected to the output end of the first servo motor (8), and multiple placement slots are provided through the upper surface of the sample feeding disk (5), and clamping structures are provided inside the multiple placement slots.

3. A liquid chromatograph with an automatic sample injection calibration device according to claim 2, characterized in that: The lifting assembly includes two fixed brackets (18) fixedly installed on the inner wall of the bottom surface of the outer shell (2). A cam (17) is rotatably installed between the two fixed brackets (18). The outer wall of the cam (17) contacts the bottom surface of the fixed plate (9). A second servo motor (16) is also fixedly installed on the bottom surface of the outer shell (2) at the position corresponding to the cam (17). The output end of the second servo motor (16) is fixedly connected to the outer wall of the cam (17).

4. A liquid chromatograph with an automatic sample injection calibration device according to claim 3, characterized in that: Spring support legs (10) are fixedly installed at the four corners of the bottom surface of the fixed plate (9), and the ends of the spring support legs (10) are fixedly connected to the inner wall of the bottom surface of the outer shell (2).

5. A liquid chromatograph with an automatic sample injection calibration device according to claim 4, characterized in that: The clamping structure includes a limiting rod (22) that is slidably connected to the sample inlet plate (5). A clamping block (21) is fixedly installed at the end of the limiting rod (22). A spring (23) is fixedly connected to the outer wall of the clamping block (21) near the sample inlet plate (5). The spring (23) is located outside the limiting rod (22) and the other end of the spring (23) is fixedly connected to the inner wall of the sample inlet plate (5).

6. A liquid chromatograph with an automatic sample injection calibration device according to claim 5, characterized in that: The outer wall of the sample feeding plate (5) and the corresponding positions of the multiple placement slots are all fixedly installed with transmitters (20), and the second servo motor (16) is fixedly installed with a receiver (24) that works with the transmitter (20). The receiver (24) is electrically connected to the second servo motor (16).

7. A liquid chromatograph with an automatic sample injection calibration device according to claim 6, characterized in that: The outer wall of the output end of the first servo motor (8) is also fixedly installed with a support tray (7) below the sample feeding plate (5).

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