Detection kit with multiple regions

Abstract

The detection kit comprises a kit body, a sample area is arranged at one end of the kit body, a pipette tip area, a combination area and a detection area are arranged behind the sample area, multiple rows of cleaning areas and a first reagent area are arranged in the combination area, and the first reagent area and the detection area are each provided with a plurality of placement positions. The cleaning area is also provided with a plurality of cleaning positions, the number of the cleaning positions corresponds to the number of the placing positions, by adopting the method and the side-by-side arrangement mode, the kit body can be used for detecting a plurality of items while the length of the kit body is not prolonged, and each item is provided with the corresponding cleaning position, so that compared with the structure of a single cleaning position in the prior art, the detection efficiency is improved. According to the method, the condition of cross contamination between product reagents can be effectively avoided, and the detection accuracy is improved; the length of the kit can be effectively reduced, and the cost of a single product can be reduced in the aspects of production, transportation and the like; and the matching degree of the instrument can be increased in the aspect of instrument matching.

Description

Technical Field

[0001] This utility model relates to the field of biochemical detection reagent technology, and in particular to a detection kit with multiple zones. Background Technology

[0002] Existing reagent kits are typically divided into multiple sections, such as Figure 1 As shown, from left to right, the reagent areas are: sample area, cleaning area, pipette tip area, reagent a area, and reagent b area. Each area performs a different function. For example, the sample area is used to place the collected samples, the cleaning area is used to clean the pipette tips, and the pipette tip area is used to place the pipette tips. After the test is completed, the pipette tips need to be cleaned. However, the existing reagent kits are limited by volume and usually only have one cleaning area, while the test items are multiple. During the process of changing pipettes, all test reagents are cleaned in one place, which can easily cause the pipette tips to adsorb other reagents, resulting in contamination. Ultimately, this may lead to deviations in the test results. Furthermore, according to the existing partitioning, adding a cleaning area would increase the reagent kit's lifespan and make it more troublesome and difficult to adapt to the instrument.

[0003] Therefore, there is an urgent need to design a multi-zone detection kit to overcome the shortcomings of one or more of the existing technologies mentioned above. Utility Model Content

[0004] The technical solution adopted by this utility model to solve the above-mentioned technical problems is: a multi-zone detection kit, characterized in that it includes: a kit body, a sample area at one end of the kit body, a pipette tip area at the rear of the sample area, a combination area at the rear of the pipette tip area, a detection area at the rear of the combination area, multiple rows of cleaning areas and a first reagent area in the combination area, both the first reagent area and the detection area having a number of placement positions, and the number of placement positions in the first reagent area and the detection area corresponding to the number of placement positions in the detection area, and the cleaning area also having a number of cleaning positions, the number of cleaning positions corresponding to the number of placement positions.

[0005] In a preferred embodiment, the bottom of the detection area is transparent.

[0006] In a preferred embodiment, the bottom of both the placement position and the cleaning position are U-shaped.

[0007] In a preferred embodiment, there is at least one cleaning position and one placement position.

[0008] The beneficial effects of this utility model are as follows: by arranging the reagents side by side, the reagent kit can perform multiple tests without extending the length of the kit body, and each test has a corresponding cleaning position. Compared with the existing single cleaning position structure, this application can effectively avoid cross-contamination between product reagents and improve the accuracy of detection; it can also effectively reduce the length of the reagent kit, thereby reducing the cost per unit in terms of production and transportation; and it can also increase the compatibility of instruments. Attached Figure Description

[0009] Figure 1 This is a schematic diagram of the existing technology;

[0010] Figure 2 This is a schematic diagram of the structure of this utility model;

[0011] Figure 3 This is a bottom view of the present invention.

[0012] In the picture:

[0013] 10. Reagent kit body; 11. Sample area; 12. Pipette tip area; 13. Combination area; 131. First reagent area; 132. Cleaning area; 133. Cleaning position; 134. Placement position; 14. Detection area. Detailed Implementation

[0014] To make the above-mentioned objects, features, and advantages of this utility model more apparent and understandable, the specific embodiments of this utility model will be described in detail below with reference to the accompanying drawings. Many specific details are set forth in the following description to provide a full understanding of this utility model. However, this utility model can be implemented in many other ways different from those described herein, and those skilled in the art can make similar modifications without departing from the spirit of this utility model. Therefore, this utility model is not limited to the specific embodiments disclosed below.

[0015] In the description of the embodiments of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "connection" and "installation" should be interpreted broadly. For example, "connection" can be a detachable connection or a non-detachable connection; it can be a direct connection or an indirect connection through an intermediate medium. Furthermore, "connection" can be a direct connection or an indirect connection through an intermediate medium. "Fixed" means that the relative positional relationship remains unchanged after the connection. The directional terms mentioned in the embodiments of this utility model, such as "inner," "outer," "top," and "bottom," are only for reference to the directions in the accompanying drawings. Therefore, the directional terms used are for better and clearer explanation and understanding of the embodiments of this utility model, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on the embodiments of this utility model.

[0016] In this embodiment of the invention, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Therefore, a feature defined with "first" and "second" may explicitly or implicitly include one or more of that feature.

[0017] In this embodiment of the utility model, "and / or" is merely a description of the relationship between related objects, indicating that three relationships can exist. For example, A and / or B can represent three situations: A exists alone, A and B exist simultaneously, and B exists alone. Additionally, the character " / " in this document generally indicates that the preceding and following related objects have an "or" relationship.

[0018] References to "one embodiment" or "some embodiments" as used in this specification mean that one or more embodiments of the present invention include a specific feature, structure, or characteristic described in connection with that embodiment. Therefore, the phrases "in one embodiment," "in some embodiments," "in other embodiments," "in still other embodiments," etc., appearing in different parts of this specification do not necessarily refer to the same embodiment, but rather mean "one or more, but not all, embodiments," unless otherwise specifically emphasized. The terms "comprising," "including," "having," and variations thereof mean "including but not limited to," unless otherwise specifically emphasized. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0019] like Figures 2-3As shown, this utility model provides a multi-zone detection kit, characterized in that it includes: a kit body 10, a sample area 11 at one end of the kit body 10, a pipette tip area 12 at the rear of the sample area 11, a combination area 13 at the rear of the pipette tip area 12, a detection area 14 at the rear of the combination area 13, and multiple rows of cleaning areas 132 and a first reagent area 131 in the combination area 13. Both the first reagent area 131 and the detection area 14 are provided with a plurality of placement positions 134, and the number of placement positions 134 in the first reagent area 131 corresponds to the number of placement positions 134 in the detection area 14. The cleaning area 132 is also provided with a plurality of cleaning positions 133, and the number of cleaning positions 133 corresponds to the number of placement positions 134.

[0020] Specifically, the reagent kit body 10 is elongated. From left to right, the reagent kit body 10 has a sample area 11 for placing the collected sample, a pipette tip area 12 for placing pipette tips, a combination area 13 for placing the first reagent component and for cleaning pipette tips, and a detection area 14 for placing the second reagent component. The combination area 13 has a row of first reagent areas 131 and a row of cleaning areas 132. Each first reagent area 131 has at least one placement position 134, each cleaning area 132 has at least one cleaning position 133, and each detection area 14 also has at least one placement position 134. The number of placement positions 134 in the first reagent area 131 corresponds to the number of placement positions 134 in the detection area 14. For example, if there are eight placement positions 134 in the detection area 14, then the number of placement positions 134 in the first reagent area 131 corresponds to the number of placement positions 134 in the detection area 14. There are also eight placement positions 134 in the reagent area 131. In this embodiment, to avoid mixed cleaning and contamination of the pipette tips during recycling, the number of cleaning positions 133 corresponds to the number of placement positions 134 in the first reagent area 131, ensuring that each test item has a corresponding cleaning position 133, thereby avoiding mixed contamination and ensuring the accuracy of the test. The number of cleaning positions 133 and placement positions 134 depends on the usage requirements and can be eight, ten, twelve, sixteen, etc. When the number is large, the width of the reagent kit body 10 can be increased, the combination area 13 can be set in multiple rows, and the placement positions in the test area 14 can be reduced to accommodate more items. This method can increase the number of test items in the reagent kit without increasing the length of the reagent kit.

[0021] Furthermore, in this embodiment, to facilitate detection, the bottom area of ​​the detection area 14 is highly transparent so that optical detection light can enter from one side and exit from the other side to be received, thereby obtaining the detection result.

[0022] Furthermore, since there are generally requirements for liquid level height during testing to ensure accuracy, in this embodiment, in order to achieve a higher liquid level even with a smaller amount of testing liquid, the bottoms of the cleaning position 133 and the placement position 134 are both set in a U-shape. By reducing the bottom volume, the liquid level height is increased to facilitate testing.

[0023] In use, place the corresponding working solutions in the sample area 11, cleaning position 133, and placement position 134. Place the pipette tip in the pipette tip area 12. After preparation, according to the set pipetting volume, first transfer the working solution in the first reagent area 131 to the corresponding detection area 14. Then add the sample from the sample area 11 to the detection area 14. Mix the three working solutions and incubate them. After the reaction time is reached, the instrument performs optical detection through the transparent area at the bottom of the detection area 14. After completing the detection of one item, return the pipette tip to the cleaning position 133 corresponding to the pipetting for cleaning, and then proceed to the next detection item until all items are completed.

[0024] In summary, by arranging reagents side-by-side, the reagent kit can perform multiple tests without increasing its overall length, and each test has a corresponding cleaning station. Compared to the existing single-cleaning-station structure, this application effectively avoids cross-contamination between reagents, improving detection accuracy. It also effectively reduces the length of the reagent kit, lowering the cost per unit in production and transportation. Furthermore, it increases instrument compatibility.

[0025] This invention is not limited to the description in the specification and embodiments. Therefore, other advantages and modifications can be readily realized by those skilled in the art. Thus, without departing from the spirit and scope of the general concept as defined by the claims and their equivalents, this invention is not limited to the specific details, representative devices and illustrated examples shown and described herein.

Claims

1. A multi-region detection kit, characterized in that, include: The reagent kit body has a sample area at one end, a pipette tip area at the rear of the sample area, a combination area at the rear of the pipette tip area, and a detection area at the rear of the combination area. The combination area has multiple rows of cleaning areas and a first reagent area. Both the first reagent area and the detection area have several placement positions, and the number of placement positions in the first reagent area corresponds to the number of placement positions in the detection area. The cleaning area also has several cleaning positions, and the number of cleaning positions corresponds to the number of placement positions.

2. The detection kit with multiple zones according to claim 1, characterized in that, The bottom of the detection area is transparent.

3. The detection kit with multiple zones according to claim 1, characterized in that, Both the placement position and the cleaning position have a "U" shaped bottom.

4. The detection kit with multiple zones according to claim 1, characterized in that, There is at least one cleaning position and one placement position.

Images