Combined type forced distribution mechanism for piston and lower cover plate of chromatographic column

Abstract

A combined forced distribution mechanism of a chromatographic column piston and a lower cover plate comprises a piston body and a lower cover plate body, fine holes are formed in the bottom of the lower cover plate body, piston liquid flow grooves are formed in the surface of the piston body, lower cover plate liquid flow grooves are formed in the surface of the lower cover plate body, and the piston liquid flow grooves are communicated with the lower cover plate liquid flow grooves. The thin holes, the piston liquid flow grooves and the lower cover plate liquid flow grooves are formed in the surfaces of the piston body and the lower cover plate body in a direct machining mode. A liquid flow groove in a first distribution piece in an original distribution mode is directly machined in the piston body, so that one distribution piece is reduced, secondary liquid flow distribution can be achieved only through one distribution piece, only one time is needed for assembling and positioning, machining and assembling are simpler and more convenient, and the production efficiency is improved. And a circular hole-shaped structure on the distribution sheet is changed into the *-shaped groove, so that the liquid distribution area of the distribution sheet is increased, and the distribution of high-speed liquid flow on the cross section is more uniform.

Description

TECHNICAL FIELD

[0001] The utility model belongs to the field of chromatographic column, specifically speaking is the combined type forced distribution mechanism of chromatographic column piston and lower cover plate. BACKGROUND

[0002] Chromatographic column is the column pipe filled with stationary phase filler to separate mixed components, it bears the separation function in chromatographic system, the traditional big diameter dynamic axial compression column distribution mechanism is to ensure that the liquid flow is evenly distributed in the radial direction of the column head, will take at least twice or more times of liquid flow distribution, the current liquid flow distribution is completed by distribution sheet, that is to say, at least two or more distribution sheets, because the piston surface must be close to the first distribution sheet, the first distribution sheet must be close to the second distribution sheet, and different distribution sheet combinations also require strict positioning, how many distribution sheets need to be positioned several times, resulting in very high processing and assembly precision of distribution sheet, otherwise it will cause liquid flow distribution to be blocked or fail.

[0003] The liquid flow outlet on the last stage distribution sheet in the tradition is circular hole, that is to say, in the case of high-speed liquid flow pump, the liquid flow is finally sprayed in the form of fine point when flowing out of the distribution sheet, therefore the big diameter dynamic axial compression column becomes countless parallel thin chromatographic columns, the laminar elution effect in the axial direction cannot be guaranteed in the operation process of chromatographic column, and often presents a final "V" separation, the separation efficiency and purification effect are difficult to satisfy people.

[0004] Therefore, the combined type forced distribution mechanism of chromatographic column piston and lower cover plate is provided to solve the above problems. CONTENT OF THE UTILITY MODEL

[0005] In order to solve the above technical problems, the utility model provides the following technical scheme:

[0006] The combined type forced distribution mechanism of chromatographic column piston and lower cover plate, including piston body and lower cover plate body, the bottom of lower cover plate body is provided with a fine hole, the surface of piston body is provided with a piston liquid flow groove, and the surface of lower cover plate body is provided with a lower cover plate liquid flow groove.

[0007] Further, in the utility model, the fine hole, the piston liquid flow groove and the lower cover plate liquid flow groove are all provided on the surface of the piston body and the lower cover plate body by direct machining.

[0008] Further, in the utility model, the liquid flow grooves and the lower cover plate liquid flow grooves are uniformly distributed on the surface of the piston body and the lower cover plate body.

[0009] Further, in the utility model, the lower cover plate liquid flow groove diverges outward in the form of "rice" with the fine hole as the center.

[0010] The utility model has the beneficial effects that:

[0011] The utility model discloses a liquid flow groove of original distribution mode's first distribution piece is directly processed to the piston body, thereby reducing a distribution piece, and only using a distribution piece can realize secondary liquid flow distribution, and assembly positioning also only needs once, and processing and assembly are more simple and convenient, the circular hole shape structure on the distribution piece is changed into the mi type recess, increases the liquid distribution area of distribution piece, and the distribution of high -speed liquid flow on the cross section is more uniform. BRIEF DESCRIPTION OF DRAWINGS

[0012] Fig. 1 It is the utility model piston body's elevation plane structure schematic diagram;

[0013] Fig. 2 It is the utility model lower cover plate body's elevation plane structure schematic diagram;

[0014] Fig. 3 It is the utility model fine hole and liquid flow groove's plane structure schematic diagram;

[0015] Fig. 4 It is the utility model piston body's real structure schematic diagram;

[0016] Fig. 5 It is the utility model lower cover plate body's real structure schematic diagram.

[0017] In the drawing:

[0018] 1, piston body;2, lower cover plate body;3, fine hole;4, piston liquid flow groove;5, lower cover plate liquid flow groove. DETAILED DESCRIPTION

[0019] In order to more understand the technical content of the utility model, specific embodiment is raised and is described as follows with the accompanying drawing.The aspects of the utility model are described with reference to the accompanying drawings in the present disclosure, and many illustrated embodiments are shown in the accompanying drawings.The embodiments of the present disclosure do not necessarily define all aspects of the utility model.It should be understood that the various concepts and embodiments introduced above, and those concepts and embodiments described in more detail below can be implemented in any one of many ways, because the concepts and embodiments disclosed by the utility model are not limited to any implementation manner.In addition, some aspects of the utility model can be used alone, or used in any appropriate combination with other aspects of the utility model.

[0020] Embodiment 1

[0021] As Figs. 1-5As shown in the first embodiment of the utility model, the embodiment provides the combined forced distribution mechanism of the piston and the lower cover plate of the chromatographic column, which comprises a piston body 1 and a lower cover plate body 2, the bottom of the lower cover plate body 2 is provided with a fine hole 3, the surface of the piston body 1 is provided with a piston liquid flow groove 4, and the surface of the lower cover plate body 2 is provided with a lower cover plate liquid flow groove 5.

[0022] As Figs. 1-5 As shown, the piston body 1 also constitutes a part of the forced distribution, and first-stage liquid flow distribution is carried out: the piston liquid flow groove 4 is uniformly distributed on the surface of the piston body 1, and when the liquid flow is pumped from the center hole position of the piston body 1 by the infusion pump, the liquid flow will first be uniformly distributed on the piston body 1, and can directly reach the end of each groove, which is equivalent to that the piston body 1 itself is a first distribution piece; the surface of the lower cover plate body 2 is uniformly provided with the piston liquid flow groove 4, and when the lower cover plate body 2 is combined with the piston body 1, the upper surface of the lower cover plate body 2 needs to be tightly attached to the surface of the piston body 1, at this time, the fine hole 3 on the lower cover plate body 2 only needs to be simply aligned with the end of the liquid flow distribution groove on the surface of the piston body 1, and the positioning operation is more convenient and easy to operate; the lower surface of the lower cover plate body 2 is provided with a plurality of independent liquid flow grooves, which are divergent outward in a "rice" shape with the fine hole 3 as the center, which is equivalent to second-stage liquid flow distribution, and the "rice" shape liquid flow groove enlarges the liquid flow distribution area, so that the liquid flow is more uniformly and widely distributed in the radial direction of the column head, and the laminar elution effect in the axial direction during the use and operation of the chromatographic column is also ensured as much as possible; in addition to the "rice" shape groove, the groove can also be a regular polygon.

[0023] Embodiment 2

[0024] Referring to Figs. 1-3 The second embodiment of the utility model is based on the previous embodiment.

[0025] In the embodiment, the fine hole 3, the piston liquid flow groove 4 and the lower cover plate liquid flow groove 5 are all provided on the surface of the piston body 1 and the lower cover plate body 2 by direct machining.

[0026] The piston liquid flow groove 4 and the lower cover plate liquid flow groove 5 are uniformly distributed on the surface of the piston body 1 and the lower cover plate body 2.

[0027] The lower cover plate liquid flow groove 5 is divergent outward in a "rice" shape with the fine hole 3 as the center.

[0028] As Figs. 1-3As shown, the lower surface of the lower cover plate body 2 has a plurality of independent liquid flow grooves, which are centered on the fine hole 3 and diverge outwardly in a "rice" shape, which corresponds to second-stage liquid flow distribution, and the "rice" shape liquid flow grooves enlarge the liquid flow distribution area, so that the liquid flow is more evenly and widely distributed in the radial direction of the column head, and the laminar flow elution effect in the axial direction during the use and operation of the chromatographic column is also ensured as much as possible.

[0029] In use, the piston body 1 also constitutes a part of forced distribution and performs first-stage liquid flow distribution, and the piston body 1 has piston liquid flow grooves 4 machined on the surface thereof and uniformly distributed on the surface of the piston body 1, and when the liquid flow is pumped from the center hole position of the piston body 1 by the infusion pump, the liquid flow will first be uniformly distributed on the piston body 1 and directly reach the end of each groove, so that the piston body 1 itself is a first distribution piece, and the surface of the lower cover plate body 2 has uniformly distributed lower cover plate liquid flow grooves 5, and when the surface of the lower cover plate body 2 is combined with the surface of the piston body 1, the fine hole 3 on the lower cover plate body 2 is simply aligned with the end of the liquid flow distribution groove on the surface of the piston body 1, so that the positioning operation is more convenient and easy to operate, and the lower surface of the lower cover plate body 2 has a plurality of independent liquid flow grooves, which are centered on the fine hole 3 and diverge outwardly in a "rice" shape, which corresponds to second-stage liquid flow distribution, and the "rice" shape liquid flow grooves enlarge the liquid flow distribution area, so that the liquid flow is more evenly and widely distributed in the radial direction of the column head, and the laminar flow elution effect in the axial direction during the use and operation of the chromatographic column is also ensured as much as possible.

[0030] The standard parts used in the present application can be purchased from the market, and can be ordered according to the description and drawings, and the specific connection mode of each part adopts the conventional means such as bolts, rivets and welding in the prior art, the mechanical parts and equipment adopt the conventional types in the prior art, the control mode is automatically controlled by a controller, and the control circuit of the controller can be realized by simple programming by a person skilled in the art, which is common knowledge in the art, and the present application is mainly used to protect mechanical devices, so the control mode and circuit connection will not be explained in detail.

[0031] Although the present application has been disclosed with reference to the preferred embodiments, it is not intended to limit the present application. Those skilled in the art can make various modifications and improvements without departing from the spirit and scope of the present application. Therefore, the protection scope of the present application shall be subject to the right claim.

Claims

1. Combined forced-dispensing mechanism for a chromatography column piston and lower cover plate, comprising a piston body (1) and a lower cover plate body (2), characterized in that: The bottom of the lower cover plate body (2) is provided with a fine hole (3), the surface of the piston body (1) is provided with a piston liquid flow groove (4), and the surface of the lower cover plate body (2) is provided with a lower cover plate liquid flow groove (5).

2. The combined forced-dispersion mechanism for a chromatography column piston and lower cover plate of claim 1, wherein: The fine hole (3), the piston liquid flow groove (4) and the lower cover plate liquid flow groove (5) are all directly machined on the surfaces of the piston body (1) and the lower cover plate body (2).

3. The combined forced-dispersion mechanism for a chromatography column piston and lower cover plate of claim 1 wherein: The piston liquid flow groove (4) and the lower cover plate liquid flow groove (5) are uniformly distributed on the surfaces of the piston body (1) and the lower cover plate body (2).

4. The combined forced-dispersion mechanism for a chromatography column piston and lower cover plate of claim 1 wherein: The lower cover plate liquid flow groove (5) diverges outward in a "rice” shape with the fine hole (3) as the center.

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