Medicament mixing device
By designing a multi-cylinder structure and a stirring roller driven drug mixing device, the mixing deficiencies of existing devices were solved, enabling independent mixing and low-temperature treatment of solid and liquid drugs, thus meeting the requirements of precision and drug activity in small-dose experiments.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- 刘世杰
- Filing Date
- 2025-05-19
- Publication Date
- 2026-04-21
AI Technical Summary
Existing drug mixing devices cannot simultaneously mix powdered materials, liquid materials, and solid-liquid mixtures. Furthermore, residual materials in the equipment may cause cross-influence, and the heat generated by friction can affect drug activity, making it difficult to meet the needs of small-dose trials.
A pharmaceutical mixing device was designed, comprising a first mixing cylinder, a second mixing cylinder, and a third mixing cylinder. It includes an inner cylinder and a stirring roller, and is equipped with a cooling component to achieve separate mixing of solid and liquid pharmaceuticals in a low-temperature environment. The stirring roller is driven to rotate at high speed by a servo motor and a stepper motor to ensure uniform mixing and pharmaceutical activity.
It enables independent mixing of solid and liquid drugs, avoiding cross-influence, maintaining drug activity, and meeting the precision and accuracy requirements of small-dose trials.
Smart Images
Figure CN224142058U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of pharmaceutical mixing technology, specifically a pharmaceutical mixing device. Background Technology
[0002] In tumor research, "traditional Chinese medicine intervention in tumor growth" refers to a class of intervention strategies that utilize traditional Chinese medicine (including natural drugs, herbal drugs, animal drugs, and mineral drugs) or its effective components to inhibit tumor development, delay progression, or enhance the effects of radiotherapy and chemotherapy through multiple mechanisms such as regulating the body's physiological functions, inhibiting tumor cell proliferation, inducing tumor cell apoptosis, blocking tumor angiogenesis, and regulating the microenvironment.
[0003] Traditional Chinese medicine requires mixing to form a pharmaceutical preparation for analysis and research. Most existing pharmaceutical mixing devices are single mixing cylinders, unable to simultaneously mix powdered materials, liquid materials, or solid-liquid mixtures. Residual materials in the equipment may cause cross-contamination, and the heat generated by friction during mixing may affect the activity of the medicine. For example, some medicines require a low-temperature reaction environment, which a simple mixing cylinder lacks. Furthermore, research experiments typically require small-scale experimental instruments, which current equipment often cannot meet. Utility Model Content
[0004] The purpose of this invention is to provide a pharmaceutical mixing device to solve the problems mentioned in the background art.
[0005] To achieve the above objectives, this utility model provides the following technical solution: a pharmaceutical mixing device, comprising a shell, a first mixing cylinder disposed inside the shell, a second mixing cylinder disposed inside the shell on one side of the first mixing cylinder, an inner cylinder disposed inside both the first and second mixing cylinders, and holes disposed at the bottom ends of both inner cylinders, a first stirring roller disposed inside the inner cylinder of the first mixing cylinder, a spiral stirring roller disposed inside the inner cylinder of the second mixing cylinder, a wall scraping assembly disposed on the upper outer surface of the spiral stirring roller, a separate discharge port disposed at the bottom ends of both the first and second mixing cylinders, a combined discharge port disposed at the bottom ends of the two opposite separate discharge ports of the first and second mixing cylinders, and a third mixing cylinder connected to the bottom ends of the two combined discharge ports, a mixing discharge port disposed at the bottom end of the third mixing cylinder, and a cooling assembly disposed on the outer surfaces of the first, second, and third mixing cylinders.
[0006] The drug mixing device of this invention is designed for small-dose drug testing research. Therefore, the consideration of precision is particularly important. The device not only needs to meet the needs of drug mixing in the experiment, but also requires a series of operations such as ultrasonic dissolution, light protection and heating in a relatively closed environment. Therefore, there are high requirements for the precision and reliability of the device. It is on this basis that the above-mentioned mixing device was designed.
[0007] Preferably, a first discharge port is provided on both sides of the shell below the two separate discharge ports, and a second discharge port is provided on one side of the shell below the mixing discharge port. A collection vessel can be placed at the positions of the two first discharge ports and the second discharge port. After the first mixing cylinder and the second mixing cylinder separately mix the solid powder and the liquid medicine, they are discharged through the two separate discharge ports for collection. The solid and liquid medicines are mixed in the third mixing cylinder, and after the mixing is completed, they can be discharged through the mixing discharge port.
[0008] Preferably, the top of the first mixing cylinder is provided with a powder material inlet, and the top of the second mixing cylinder is provided with a liquid material inlet. Both the powder material inlet and the liquid material inlet are equipped with solenoid valves. After the materials are put into the first mixing cylinder and the second mixing cylinder respectively, the solenoid valves are closed to prevent the materials from splashing out during mixing.
[0009] Preferably, the third mixing drum is equipped with a second stirring roller. When liquid and solid materials are put into the third mixing drum, the second stirring roller rotates to mix the materials thoroughly.
[0010] Preferably, a first mixing cylinder extends from the top of the first stirring roller, a second mixing cylinder extends from the top of the spiral stirring roller, and the bottom ends of the two inner cylinders extend into a first mixing cylinder and a second mixing cylinder respectively via columns. Servo motors are respectively installed at the extended ends of the first stirring roller, the spiral stirring roller, and the inner cylinders. The servo motors of the first stirring roller and the spiral stirring roller drive the first stirring roller and the spiral stirring roller to rotate at high speed, so that the materials are fully mixed. The servo motor of the inner cylinder contains a reducer, which can drive the inner cylinder to rotate at a certain angle.
[0011] Preferably, a third mixing cylinder extends from the bottom of the second stirring roller, and a stepper motor is installed at the extended end of the second stirring roller. The stepper motor drives the third mixing cylinder to rotate at high speed, so that the solid material and the liquid material are fully mixed.
[0012] Compared with the prior art, the beneficial effects of this utility model are:
[0013] 1. This drug mixing device consists of a miniature first mixing cylinder, a second mixing cylinder, and a third mixing cylinder. The first and second mixing cylinders each have an inner cylinder. The inner cylinder adjusts the feeding position of the mixed material, allowing for separate mixing of solid and liquid drugs. This avoids cross-contamination due to equipment residues. After the solid and liquid drugs are mixed separately, they can be fed into the third mixing cylinder for further mixing. This initial mixing of powdered materials and liquid drugs before mutual mixing reduces solid agglomeration. The drug mixing device can perform drug mixing operations in different states according to the different needs of traditional Chinese medicine intervention in tumor growth in tumor research.
[0014] 2. This pharmaceutical mixing device cools the first, second, and third mixing cylinders by enclosing them with cooling components and a shell, thus preventing the heat generated by material friction and pharmaceutical reaction during mixing from affecting the activity of the pharmaceuticals.
[0015] 3. This reagent mixing device has high internal precision, which can meet the needs of various small-dose drug tests. It is easy to operate and helps to improve the accuracy of test results. Attached Figure Description
[0016] Figure 1 This is a schematic diagram of the overall structure of this utility model;
[0017] Figure 2 This is a cross-sectional schematic diagram of the shell structure of this utility model;
[0018] Figure 3 This is a schematic cross-sectional view of the first mixing cylinder, the second mixing cylinder, and the third mixing cylinder of this utility model;
[0019] Figure 4 This is a cross-sectional schematic diagram of the first mixing cylinder structure of this utility model.
[0020] In the diagram: 1. Shell; 2. Liquid feed port; 3. First mixing cylinder; 4. Second mixing cylinder; 5. Powder material feed port; 6. First discharge port; 7. Second discharge port; 8. Cooling component; 9. Individual discharge port; 10. Third mixing cylinder; 11. Mixed discharge port; 12. Inner cylinder; 13. First stirring roller; 14. Collecting discharge port; 15. Wall scraping component; 16. Spiral stirring roller; 17. Second stirring roller; 18. Hole. Detailed Implementation
[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0022] like Figures 1 to 4As shown, the pharmaceutical mixing device of this embodiment includes a housing 1, inside which a first mixing cylinder 3 is disposed. A second mixing cylinder 4 is disposed inside the housing 1 on one side of the first mixing cylinder 3. Both the first mixing cylinder 3 and the second mixing cylinder 4 have inner cylinders 12, which are respectively matched with the first mixing cylinder 3 and the second mixing cylinder 4 and can rotate inside them. The bottom ends of both inner cylinders 12 are provided with holes 18. A first stirring roller 13 is disposed inside the inner cylinder 12 of the first mixing cylinder 3. The circumferential surface of the first stirring roller 13 is provided with several protrusions. When the first stirring roller 13 rotates, it stirs the corresponding inner cylinder 1... 2. The solid materials inside the first mixing cylinder 3 are stirred and mixed. A spiral stirring roller 16 is installed inside the inner cylinder 12 of the second mixing cylinder 4. When the spiral stirring roller 16 rotates, it causes the liquid materials inside the corresponding inner cylinder 12 to generate vortices, so that the materials are fully mixed. A wall scraping assembly 15 is provided on the upper outer surface of the spiral stirring roller 16. The wall scraping assembly 15 matches the inner cylinder 12. When the wall scraping assembly 15 is driven to rotate by the spiral stirring roller 16, the outer surface of the wall scraping assembly 15 scrapes the inner wall of the corresponding inner cylinder 12, preventing the materials from sticking to the inner wall of the inner cylinder 12. The bottom ends of the first mixing cylinder 3 and the second mixing cylinder 4 are provided with separate discharge ports 9. The two separate discharge ports 9 are opposite to the first mixing cylinder 4. The bottom ends of the inner cylinder 3 and the second mixing cylinder 4 are respectively provided with a collection discharge port 14. The hole 18 opened at the bottom end of the inner cylinder 12 matches the individual discharge port 9 and the collection discharge port 14. When the inner cylinder 12 rotates, so that the hole 18 coincides with the individual discharge port 9, the material is discharged from the individual discharge port 9. When the inner cylinder 12 rotates, so that the hole 18 coincides with the collection discharge port 14, the material is discharged from the collection discharge port 14. The bottom ends of the two collection discharge ports 14 are connected to the third mixing cylinder 10. When mixing liquid and solid materials, the liquid and solid materials are respectively fed into the third mixing cylinder 10 from the two collection discharge ports 14 for mixing. The bottom of the third mixing cylinder 10 The first mixing cylinder 3, the second mixing cylinder 4, and the third mixing cylinder 10 are all equipped with a mixing discharge port 11. After the materials are fully mixed inside the third mixing cylinder 10, they can be discharged from the mixing discharge port 11. Cooling components 8 are provided on the outer surfaces of the first mixing cylinder 3, the second mixing cylinder 4, and the third mixing cylinder 10. There are three cooling components 8. The cooling components 8 contain copper pipes and circulating water tanks. The copper pipes are respectively wrapped around the outer surfaces of the first mixing cylinder 3, the second mixing cylinder 4, and the third mixing cylinder 10. Cooling liquid flows inside the copper pipes and circulates through the circulating water tank. The first mixing cylinder 3, the second mixing cylinder 4, and the third mixing cylinder 10 are cooled by heat exchange to prevent the temperature from being too high when the materials are mixed, which would affect the drug activity.
[0023] Specifically, a first discharge port 6 is provided on both sides of the shell 1 below the two separate discharge ports 9, and a second discharge port 7 is provided on one side of the shell 1 below the mixing discharge port 11. Collection containers can be placed at the positions of the two first discharge ports 6 and the two discharge ports 7. After the first mixing cylinder 3 and the second mixing cylinder 4 separately mix the solid powder and the liquid medicine, they are discharged through the two separate discharge ports 9 for collection. The solid and liquid medicines are mixed in the third mixing cylinder 10, and after the mixing is completed, they can be discharged through the mixing discharge port 11.
[0024] Furthermore, the top of the first mixing cylinder 3 is provided with a powder material inlet 5, and the top of the second mixing cylinder 4 is provided with a liquid material inlet 2. Both the powder material inlet 5 and the liquid material inlet 2 are equipped with solenoid valves. After the materials are put into the first mixing cylinder 3 and the second mixing cylinder 4 respectively, the solenoid valves are closed to prevent the materials from splashing out during mixing.
[0025] Furthermore, a second stirring roller 17 is provided inside the third mixing cylinder 10. When liquid and solid materials are put into the third mixing cylinder 10, the second stirring roller 17 rotates to mix the materials thoroughly.
[0026] Furthermore, a first mixing cylinder 3 extends from the top of the first stirring roller 13, and a second mixing cylinder 4 extends from the top of the spiral stirring roller 16. The bottom ends of the two inner cylinders 12 extend from the first mixing cylinder 3 and the second mixing cylinder 4 respectively through columns. Servo motors are installed at the extended ends of the first stirring roller 13, the spiral stirring roller 16 and the inner cylinder 12 respectively. The servo motors of the first stirring roller 13 and the spiral stirring roller 16 drive the first stirring roller 13 and the spiral stirring roller 16 to rotate at high speed, so that the materials are fully mixed. The servo motor of the inner cylinder 12 contains a reducer, which can drive the inner cylinder 12 to rotate at a certain angle.
[0027] Furthermore, a third mixing cylinder 10 extends from the bottom of the second stirring roller 17. A stepper motor is installed at the extended end of the second stirring roller 17. The stepper motor drives the third mixing cylinder 10 to rotate at high speed, so that the solid materials and liquid materials are fully mixed.
[0028] The method of use in this embodiment is as follows: In the research of traditional Chinese medicine intervention for tumor growth, it is necessary to mix different components of traditional Chinese medicine to prepare a drug. In the preparation of the drug, it may be necessary to mix liquid drugs separately, mix solid drugs separately, and mix liquid drugs with solid drugs. When mixing and dispensing the drug, the liquid drug is put into the inner cylinder 12 inside the second mixing cylinder 4 through the liquid feed port 2. The spiral stirring roller 16 rotates to generate a vortex in the liquid material to mix the drug. At the same time, the outer surface of the wall scraping component 15 scrapes the inner wall of the corresponding inner cylinder 12 to prevent the material from sticking to the inner wall of the inner cylinder 12. The solid material is put into the inner cylinder 12 inside the first mixing cylinder 3 through the powder material feed port 5. The first stirring roller 13 rotates to stir the solid material inside the corresponding inner cylinder 12. The mixing process is as follows: When the inner cylinder 12 rotates, causing the hole 18 to coincide with the individual discharge port 9, the material is discharged from the individual discharge port 9, allowing the separately mixed solid and liquid drugs to be removed. When the inner cylinder 12 rotates, causing the hole 18 to coincide with the collection discharge port 14, the material is discharged from the collection discharge port 14. The bottom ends of the two collection discharge ports 14 are connected to the third mixing cylinder 10. When mixing liquid and solid materials, the liquid and solid materials are fed into the third mixing cylinder 10 from the two collection discharge ports 14 respectively for mixing. After mixing, the material is discharged from the mixing discharge port 11. During the material mixing operation, the cooling component 8 cools the first mixing cylinder 3, the second mixing cylinder 4, and the third mixing cylinder 10 to prevent the temperature from being too high during material mixing, which could affect the drug activity.
[0029] It should be noted that the above embodiments are only used to illustrate the technical solution of this utility model and not to limit the technical solution. Although the applicant has described the utility model in detail with reference to the preferred embodiments, those skilled in the art should understand that any modifications or equivalent substitutions made to the technical solution of this utility model that do not depart from the spirit and scope of this technical solution should be covered within the scope of the claims of this utility model.
Claims
1. A medicament mixing device comprising a housing (1), characterised in that: The shell (1) is provided with a first mixing cylinder (3) inside, and a second mixing cylinder (4) is provided inside the shell (1) on one side of the first mixing cylinder (3). Both the first mixing cylinder (3) and the second mixing cylinder (4) are provided with inner cylinders (12). The bottom ends of the two inner cylinders (12) are provided with holes (18). The inner cylinder (12) of the first mixing cylinder (3) is provided with a first stirring roller (13), and the inner cylinder (12) of the second mixing cylinder (4) is provided with a spiral stirring roller (16). The upper outer surface of the spiral stirring roller (16) is provided with a scraper. The wall assembly (15) has a separate discharge port (9) at the bottom of the first mixing cylinder (3) and the second mixing cylinder (4). The bottom of the first mixing cylinder (3) and the second mixing cylinder (4) opposite to the two separate discharge ports (9) are respectively provided with a collection discharge port (14). The bottom of the two collection discharge ports (14) are connected to a third mixing cylinder (10). The bottom of the third mixing cylinder (10) is provided with a mixing discharge port (11). The outer surfaces of the first mixing cylinder (3), the second mixing cylinder (4) and the third mixing cylinder (10) are all provided with a cooling assembly (8).
2. The medicament mixing device of claim 1, wherein: The two individual discharge ports (9) are provided with a first discharge port (6) on both sides of the housing (1) below the two discharge ports (9), and the mixed discharge port (11) is provided with a second discharge port (7) on one side of the housing (1).
3. The medicament mixing device of claim 2, wherein: The top of the first mixing cylinder (3) is provided with a powder material feeding port (5), and the top of the second mixing cylinder (4) is provided with a liquid feeding port (2).
4. The medicament mixing device of claim 3, wherein: The third mixing cylinder (10) is equipped with a second stirring roller (17).
5. The medicament mixing device of claim 4, wherein: The top end of the first stirring roller (13) extends into a first mixing cylinder (3), the top end of the spiral stirring roller (16) extends into a second mixing cylinder (4), the bottom ends of the two inner cylinders (12) extend into a first mixing cylinder (3) and a second mixing cylinder (4) respectively through columns, and servo motors are respectively installed at the extension ends of the first stirring roller (13), the spiral stirring roller (16) and the inner cylinder (12).
6. The medicament mixing device of claim 5, wherein: A third mixing cylinder (10) extends from the bottom of the second stirring roller (17), and a stepper motor is installed at the extended end of the second stirring roller (17).