Fermentation tank for enzyme preparation production
By incorporating a compressed air distributor and stirring blades within the fermenter, the problem of uneven dissolved oxygen was solved, achieving efficient oxygen supply and uniform mixing, thereby improving fermentation efficiency and quality.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- JILIN AOGU BIOTECHNOLOGY CO LTD
- Filing Date
- 2025-05-21
- Publication Date
- 2026-04-28
AI Technical Summary
The existing fermenters have low and uneven dissolved oxygen levels, which leads to a decline in fermentation efficiency and quality. In particular, in large fermenters, oxygen has difficulty penetrating to the core area, resulting in low dissolved oxygen transfer efficiency.
First and second compressed air distributors are installed at the bottom of the fermenter to distribute oxygen evenly through aeration pipes. Combined with the design of stirring blades to enhance turbulence, and with the help of dissolved oxygen sensors and gas flow control valves for dynamic adjustment, the oxygen supply is ensured to be uniform.
It significantly improves dissolved oxygen uniformity and oxygen transfer efficiency, ensuring sufficient oxygen supply in all areas of the fermenter, enhancing fermentation efficiency and material mixing uniformity, and preventing contamination by miscellaneous bacteria.
Smart Images

Figure CN224172743U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of enzyme preparation processing technology, and in particular to a fermenter for enzyme preparation production. Background Technology
[0002] Fermentation is one of the core steps in enzyme preparation production. It mainly involves using fermenters to provide a controlled fermentation environment for microorganisms or cells, and by precisely controlling parameters such as temperature, pH, dissolved oxygen, and nutrient supply, it enables the efficient expression and accumulation of enzymes.
[0003] In the field of enzyme production, dissolved oxygen level is a core factor determining the fermentation efficiency and product quality of aerobic enzyme preparations. For example, the fermentation of aerobic enzyme preparations such as cellulase and amylase requires ensuring a good dissolved oxygen level in the fermenter to guarantee efficient fermentation.
[0004] Some existing fermenters rely on a single air inlet design, which leads to uneven oxygen distribution within the tank. This is especially true in large fermenters, where oxygen has difficulty penetrating to the core area and cannot mix well with the fermentation broth. This results in low dissolved oxygen transfer efficiency and uneven dissolved oxygen distribution within the tank, thereby reducing fermentation efficiency and quality.
[0005] Therefore, it is necessary to provide a fermenter for the production of enzyme preparations with high dissolved oxygen content and uniform dissolved oxygen. Utility Model Content
[0006] To address the technical problem of low fermentation efficiency caused by low and uneven dissolved oxygen levels in existing fermenters, this invention provides a fermenter for enzyme preparation production.
[0007] A high-dissolved-oxygen fermenter for enzyme preparation production includes a tank body with a heating jacket fixedly fitted to the outside. A feed inlet is located at the top of the tank body. A rotating motor is located above the tank body, and a rotating shaft is located inside the tank body. Several stirring blades are symmetrically arranged on both sides of the rotating shaft, and one end of the rotating shaft is connected to the output shaft of the rotating motor. Several equally spaced protrusions are provided at the top and bottom ends of the stirring blades. A first compressed air distributor and a second compressed air distributor are located at the bottom of the tank body. Several aeration pipes are spaced apart between the first and second compressed air distributors. Each aeration pipe has several aeration holes, and one end of each aeration pipe is connected to the first compressed air distributor, and the other end is connected to the second compressed air distributor. The first and second compressed air distributors are each connected to an oxygen supply mechanism via an air inlet pipe. A sterilization filter and a gas flow control valve are provided on the air inlet pipe. A dissolved oxygen sensor for detecting the dissolved oxygen level inside the tank body is also provided on the inner side wall of the tank body.
[0008] Preferably, the heating jacket includes a box disposed outside the tank, the box containing a heat-conducting medium, and the heat-conducting medium containing a plurality of constant-temperature heating tubes.
[0009] Preferably, the housing is provided with a heat-conducting medium inlet and a heat-conducting medium outlet.
[0010] Preferably, a temperature sensor for detecting the temperature inside the tank is provided at the top of the tank body.
[0011] Preferably, the dissolved oxygen sensor is an optical dissolved oxygen sensor; and the sterilization filter is a hydrophobic sterilization filter.
[0012] Preferably, the inner wall of the tank is provided with a plurality of annular grooves along the direction near the bottom of the tank, and an annular heat-insulating transparent tube is installed in each of the annular grooves, and an annular ultraviolet lamp is installed in each of the heat-insulating transparent tubes.
[0013] Preferably, the feed inlet includes a feed pipe disposed at the top of the tank body, and each feed pipe is provided with a feed hopper. Inside the feed pipe, a diversion screen plate is provided along the direction close to the feed pipe outlet.
[0014] Preferably, a discharge port is provided on one side of the bottom of the tank, and a first solenoid valve is provided on both the inlet and the outlet.
[0015] The beneficial effects of this utility model are as follows: This utility model provides a fermenter for enzyme preparation production. By setting a first compressed air distributor and a second compressed air distributor at the bottom of the tank body, and connecting the first and second compressed air distributors at both ends with several aeration pipes, oxygen in the air inlet pipe is evenly distributed to each aeration pipe through the first and second compressed air distributors. The oxygen is then released into the fermentation liquid in the form of microbubbles through the aeration holes of the aeration pipes. This significantly increases the gas-liquid contact area, improves dissolved oxygen uniformity, and enhances oxygen transfer efficiency, thereby ensuring that all areas of the tank body receive sufficient oxygen supply and effectively improving fermentation efficiency. At the same time, by setting protrusions at the top and bottom of the stirring blades, the turbulence of the stirred liquid can be enhanced, thereby improving the stirring effect, making the material mix more uniform, increasing the dissolved oxygen rate of the material in the tank body, and thus improving the fermentation effect.
[0016] In addition, a dissolved oxygen sensor is installed to monitor the dissolved oxygen level in the tank in real time, and in conjunction with a gas flow control valve, the oxygen supply can be dynamically adjusted; a sterilization filter is also installed to ensure that the oxygen introduced is sterile and to prevent bacteria from contaminating the materials in the tank. Attached Figure Description
[0017] Figure 1 A three-dimensional structural diagram of a fermenter for enzyme preparation production provided by this utility model;
[0018] Figure 2 A simplified structural diagram of the aeration pipe, the first compressed air distributor, and the second compressed air distributor provided by this utility model.
[0019] Attached Figure Labels
[0020] 1. Tank body; 2. Heating jacket; 3. Feed inlet; 31. Feed pipe; 32. Feed hopper; 33. Diverter screen; 4. Rotary motor; 5. Rotating shaft; 6. Agitator blades; 7. Protrusion; 8. First compressed air distributor; 9. Second compressed air distributor; 10. Aeration pipe; 11. Aeration hole; 12. Sterilization filter; 13. Gas flow control valve; 14. Dissolved oxygen sensor; 15. Temperature sensor; 16. Ring ultraviolet lamp; 17. Air inlet pipe. Detailed Implementation
[0021] The embodiments described below are merely some embodiments of this utility model, and not all embodiments. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without inventive effort are within the scope of protection of this utility model.
[0022] refer to Figure 1 As shown, refer to Figure 1 As shown, this utility model discloses a fermenter for enzyme preparation production, including a tank body 1, with a feed inlet 3 at the top of the tank body 1; and a discharge outlet (not shown in the figure) on one side of the bottom of the tank body 1. Both the feed inlet and the discharge outlet are equipped with a first solenoid valve (not shown in the figure).
[0023] Specifically, the feed inlet 3 includes a feed pipe 31 located at the top of the tank body 1, and each feed pipe 31 is provided with a feed hopper 32. Inside the feed pipe 31, a diversion screen plate 33 is provided along the direction close to the outlet of the feed pipe 31.
[0024] The diversion sieve plate 33 disperses the material entering the tank 1 into multiple fine streams through the sieve hole structure, avoiding local accumulation caused by concentrated material feeding, and can significantly increase the contact area between the material and the fermentation liquid, promoting the rapid utilization of substrate by microorganisms, thereby improving the synthesis efficiency of enzyme preparations.
[0025] A heating jacket 2 is fixedly fitted onto the outside of the tank body 1. The heating jacket 2 includes a box 21 disposed outside the tank body 1. The box 21 contains a heat-conducting medium, and a plurality of constant-temperature heating tubes 22 are disposed within the heat-conducting medium. The box 21 is provided with a heat-conducting medium inlet 23 and a heat-conducting medium outlet 24. A temperature sensor 15 for detecting the temperature inside the tank body 1 is provided at the top of the tank body 1. In this invention, the heat-conducting medium is water.
[0026] The constant-temperature heating tube 22 heats the heat-conducting medium inside the chamber 21, thereby transferring heat to the tank 1. This allows for preheating and drying of the tank 1 before production, creating a dry storage environment. It also allows for precise temperature control of the materials inside the tank 1 using the temperature sensor 15, maintaining a suitable temperature during enzyme production and ensuring efficient production. The presence of a heat-conducting medium inlet 21 and outlet 22 facilitates the replacement of the cooling medium and maintains its good thermal conductivity.
[0027] A rotating motor 4 is provided above the tank body 1, and a rotating shaft 5 is provided inside the tank body 1. Several stirring blades 6 are symmetrically arranged on both sides of the rotating shaft 5, and one end of the rotating shaft 5 is connected to the output shaft of the rotating motor 4. Several equally spaced protrusions 7 are provided at the top and bottom of the stirring blades 6.
[0028] Through the synergistic effect of the stirring blades and protrusions, micron-sized bubbles can be formed in tank 1, and the turbulent field formed by stirring can be strengthened. This enhances the turbulence of the stirred liquid, thereby improving the stirring effect, making the material mix more uniform, increasing the dissolved oxygen rate of the material in tank 1, and thus improving the fermentation effect.
[0029] The bottom of the tank 1 is provided with a first compressed air distributor 8 and a second compressed air distributor 9; a plurality of aeration pipes 10 are arranged at intervals between the first compressed air distributor 8 and the second compressed air distributor 9, each aeration pipe 10 is provided with a plurality of aeration holes 11, and each aeration pipe 10 is connected at one end to the first compressed air distributor 8 and at the other end to the second compressed air distributor 9; the first compressed air distributor 8 and the second compressed air distributor 9 are respectively connected to an oxygen supply mechanism through an air inlet pipe 17.
[0030] By installing a first compressed air distributor 8 and a second compressed air distributor 9 at the bottom of the tank 1, and connecting the two ends of the first compressed air distributor 8 and the second compressed air distributor 9 respectively with several aeration pipes 10, the oxygen in the air inlet pipe 17 is evenly distributed to each aeration pipe 10 through the first compressed air distributor 8 and the second compressed air distributor 9, and released into the fermentation liquid in the form of microbubbles through the aeration holes of the aeration pipes 10. This significantly increases the gas-liquid contact area, improves the uniformity of dissolved oxygen, and enhances the oxygen transfer efficiency, thereby ensuring that all areas in the tank 1 can obtain sufficient oxygen supply and effectively improve the fermentation efficiency.
[0031] The air inlet pipe 17 is equipped with a sterilization filter 12 and a gas flow control valve 13; the inner wall of the tank 1 is also equipped with a dissolved oxygen sensor 14 for detecting the dissolved oxygen content in the tank 1. In this embodiment, the dissolved oxygen sensor 14 is an optical dissolved oxygen sensor; the sterilization filter 12 is a hydrophobic sterilization filter.
[0032] By setting up a dissolved oxygen sensor 14 to monitor the dissolved oxygen level in tank 1 in real time, and cooperating with the gas flow control valve 13, the oxygen supply can be dynamically adjusted; by setting up a sterilization filter 12, microorganisms that may exist in the oxygen entering through the air inlet pipe 17 can be filtered out, ensuring that the oxygen is sterile and preventing bacteria from contaminating the materials in the tank.
[0033] The inner wall of the tank 1 is provided with a number of annular grooves (not shown in the figure) along the direction near the bottom of the tank 1. An annular heat-insulating transparent tube (not shown in the figure) is installed in each of the annular grooves, and an annular ultraviolet lamp 16 is installed in each of the heat-insulating transparent tubes.
[0034] By installing annular heat-insulating transparent tubes in several grooves on the inner wall of tank 1, and installing an annular ultraviolet lamp 16 inside these tubes, ultraviolet disinfection can be performed on the inside of tank 1 before use. This kills bacteria inside tank 1, ensuring a sterile environment and preventing bacteria from affecting the production and fermentation of enzyme preparations, thus guaranteeing the normal progress of subsequent enzyme preparation production and fermentation. The annular heat-insulating transparent tubes can significantly reduce the impact of the heat generated by the annular ultraviolet lamp 16 during operation on the internal temperature of tank 1, thereby maintaining the stability of the internal temperature of tank 1. In this embodiment, the annular heat-insulating transparent tubes are made of high borosilicate glass, and the outer surface of the tubes is on the same plane as the inner wall of tank 1.
[0035] This invention provides a fermenter for enzyme preparation production. Oxygen from the air inlet pipe is evenly distributed to each aeration pipe via a first and second compressed air distributor, and released into the fermentation liquid in the form of microbubbles through the aeration holes 11 of the aeration pipe 10. This significantly increases the gas-liquid contact area, improves dissolved oxygen uniformity, and enhances oxygen transfer efficiency, ensuring sufficient oxygen supply to all areas within the tank and effectively improving fermentation efficiency. Simultaneously, by providing protrusions 7 at the top and bottom of the stirring blades 6, the turbulence of the stirred liquid is enhanced, thereby improving the stirring effect and making the material mix more uniform. This increases the dissolved oxygen rate of the material within the tank 1, thus improving the fermentation effect.
[0036] The above-disclosed embodiments are merely some preferred embodiments of the present utility model, and should not be construed as limiting the scope of the present utility model. Therefore, any equivalent changes made in accordance with the scope of the present utility model patent application shall still fall within the scope of the present utility model.
Claims
1. A fermenter for enzyme preparation production, comprising a tank body, characterized in that, A heating jacket is fixedly sleeved on the outside of the tank; a feed inlet is provided at the top of the tank; a rotating motor is provided above the tank; a rotating shaft is provided inside the tank; several stirring blades are symmetrically arranged on both sides of the rotating shaft; and one end of the rotating shaft is connected to the output shaft of the rotating motor; several equally spaced protrusions are provided at the top and bottom of the stirring blades respectively. The bottom of the tank is provided with a first compressed air distributor and a second compressed air distributor; a number of aeration pipes are provided between the first compressed air distributor and the second compressed air distributor, and each aeration pipe is provided with a number of aeration holes, and one end of each aeration pipe is connected to the first compressed air distributor and the other end is connected to the second compressed air distributor. The first compressed air distributor and the second compressed air distributor are respectively connected to an oxygen supply mechanism through an air inlet pipe; and the air inlet pipe is equipped with a sterilization filter and a gas flow control valve. The inner side wall of the tank is also equipped with a dissolved oxygen sensor for detecting the amount of dissolved oxygen inside the tank.
2. The fermenter for enzyme preparation production according to claim 1, characterized in that, The heating jacket includes a box set outside the tank body, the box body is filled with a heat-conducting medium, and the heat-conducting medium is provided with a number of constant temperature heating tubes.
3. The fermenter for enzyme preparation production according to claim 2, characterized in that, The housing is provided with a heat-conducting medium inlet and a heat-conducting medium outlet.
4. The fermenter for enzyme preparation production according to claim 1, characterized in that, A temperature sensor for detecting the temperature inside the tank is installed at the top of the tank.
5. A fermenter for enzyme preparation production according to claim 1, characterized in that, The dissolved oxygen sensor is an optical dissolved oxygen sensor; the sterilization filter is a hydrophobic sterilization filter.
6. A fermenter for enzyme preparation production according to claim 1, characterized in that, The inner wall of the tank is provided with several annular grooves along the direction near the bottom of the tank. Each annular groove is equipped with an annular heat-insulating transparent tube, and each heat-insulating transparent tube is equipped with an annular ultraviolet lamp.
7. A fermenter for enzyme preparation production according to claim 1, characterized in that, The housing is provided with a heat-conducting medium inlet and a heat-conducting medium outlet.
8. A fermenter for enzyme preparation production according to claim 1, characterized in that, The feed inlet includes a feed pipe located at the top of the tank, and each feed pipe is equipped with a feed hopper. Inside the feed pipe, a diversion screen plate is provided along the direction near the feed pipe outlet.
9. A fermenter for enzyme preparation production according to claim 1, characterized in that, A discharge port is provided on one side of the bottom of the tank, and a first solenoid valve is provided on both the inlet and the outlet.