Elisa plate support and elisa plate with same

Abstract

The elisa plate support comprises an elisa plate body, a plurality of placing grooves are formed in the elisa plate body, an array of sample cups are placed in each placing groove, and limiting assemblies are arranged on the front side and the rear side of the elisa plate body and can lock the array of sample cups in the placing grooves. The front-and-back movement is limited; the adjacent independent sample cups are connected into a whole in a pressing and buckling manner, so that relative shaking is reduced; the bottom limiting groove is preliminarily positioned and supported from below. The multiple fixing structures effectively avoid shaking of the sample cup during transfer or vibration, the risk of liquid overflow is reduced, sample loss and cross contamination are reduced, and the accuracy and reliability of experimental results are improved.

Description

Technical Field

[0001] This utility model relates to the field of enzyme-linked immunosorbent assay (ELISA) plate technology, and in particular to an ELISA plate support and an ELISA plate having the support. Background Technology

[0002] In enzyme-linked immunosorbent assays (ELISA), ELISA plates play a crucial role in determining the purity, concentration, and ratio of antigens, antibodies, and labeled antibodies or antigens involved in the immunological reaction; as well as the type, concentration, ionic strength, pH value, reaction temperature, and time of the buffer solution. ELISA plates also play an indispensable role in bacterial endotoxin testing. In bacterial endotoxin testing, the ELISA plate, as the container for the reaction between the Limulus Amebocyte Lysate (LAL) reagent and the sample, participates in the entire process of bacterial endotoxin testing and influences its results.

[0003] Currently available ELISA plates, while capable of accommodating multiple sets of sample cups arranged side-by-side, are prone to shaking during plate transfer due to external force or vibration. Because existing ELISA plates lack an effective fixation structure, liquid spillage is common during shaking, leading to sample loss, potential cross-contamination, and compromised accuracy and reliability of experimental results. To address these issues, we propose an ELISA plate holder and an ELISA plate incorporating this holder. Utility Model Content

[0004] The purpose of this section is to outline some aspects of embodiments of the present invention and to briefly describe some preferred embodiments. Simplifications or omissions may be made in this section, as well as in the abstract and title of the present invention, to avoid obscuring the purpose of these documents, and such simplifications or omissions should not be construed as limiting the scope of the present invention.

[0005] Therefore, the purpose of this invention is to provide an ELISA plate holder and an ELISA plate with the holder, which can solve the problem that although current ELISA plates on the market can accommodate multiple sets of sample cups arranged side by side, in actual operation, when the ELISA plate needs to be transferred, external force or vibration during the movement can easily cause the sample cups to shake. Because existing ELISA plates lack an effective fixing structure, liquid is prone to spillage during shaking, which not only causes sample loss but may also lead to cross-contamination, affecting the accuracy and reliability of experimental results.

[0006] To solve the above-mentioned technical problems, this utility model provides an enzyme-labeled plate holder and an enzyme-labeled plate having the holder, and adopts the following technical solution: it includes an enzyme-labeled plate body, the enzyme-labeled plate body has multiple placement slots inside, each placement slot has a row of sample cups placed inside, and the enzyme-labeled plate body has limiting components on the front and rear sides.

[0007] The limiting component includes two fixing rods, both of which are fixedly installed on the surface of the ELISA plate body. A baffle is fixedly provided at the end of each fixing rod away from the ELISA plate body. First limiting plates are fixedly provided at both ends of the sample cups. Limiting holes are provided on the surface of each of the two first limiting plates. Second limiting plates are slidably provided on the outside of the two fixing rods. Limiting posts that match the limiting holes are fixedly provided on the surface of the second limiting plates. Springs are sleeved on the outside of each of the two fixing rods.

[0008] Preferably, the array of sample cups includes multiple independent sample cups, and each independent sample cup has a locking plate and a buckle plate fixedly installed on its front and rear sides, respectively, and the buckle plate is connected to the adjacent locking plate by a snap-fit ​​connection.

[0009] Preferably, a pressing block is fixedly provided on the outside of the second limiting plate, the spring is located between the enzyme labeling plate body and the pressing block, and the baffle is located between the second limiting plate and the pressing block.

[0010] Preferably, each of the placement slots has multiple limiting slots inside, and the bottom of each individual sample cup is respectively placed in the corresponding limiting slot.

[0011] Preferably, a support body is provided directly below the enzyme-labeled plate body, and the support body includes four independently placed plates.

[0012] Preferably, each of the four independently placed plates is fixedly provided with a limiting frame on its top, and the enzyme-labeled plate body is inserted into the corresponding limiting frame.

[0013] In summary, this utility model has at least one of the following beneficial effects: 1. Through the cooperation of the limiting components, the entire row of sample cups can be locked in the placement groove, restricting their forward and backward movement; adjacent independent sample cups are connected by snap-fit ​​to form a whole, reducing relative shaking; the bottom limiting groove provides initial positioning and support from below. The multiple fixing structures effectively prevent sample cups from shaking during transfer or vibration, reducing the risk of liquid spillage, reducing sample loss and cross-contamination, and improving the accuracy and reliability of experimental results.

[0014] 2. The four independently placed plates of the support body are equipped with a limiting frame at the top, which can be used to insert the ELISA plate body and restrict its movement from the bottom and sides; the spring of the limiting component provides continuous reset force, and locking and unlocking operations are convenient. The overall structure not only enhances the stability of the ELISA plate during transfer and operation, but also simplifies the installation and replacement process of sample cups, improving the convenience and efficiency of experimental operations. Attached Figure Description

[0015] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0016] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0017] Figure 2 This is a schematic diagram of the structure of the enzyme-labeled plate of this utility model;

[0018] Figure 3 This is a cross-sectional view of the side structure of the enzyme-labeled plate body of this utility model;

[0019] Figure 4 For the present utility model Figure 3 Enlarged schematic diagram of the structure at point A in the middle;

[0020] Figure 5 This is a schematic diagram of the internal structure of the placement slot of this utility model.

[0021] The components represented by each number in the attached diagram are as follows: 1. Plate body; 2. Placement slot; 3. Sample cups; 4. Fixing rod; 5. Baffle; 6. First limiting plate; 7. Limiting hole; 8. Second limiting plate; 9. Limiting post; 10. Spring; 11. Individual sample cup; 12. Locking plate; 13. Buckle plate; 14. Pressing block; 15. Limiting slot; 16. Support body; 17. Individual placement plate; 18. Limiting frame. Detailed Implementation

[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0023] The following is in conjunction with the appendix Figure 1 —5. This utility model will be described in further detail.

[0024] In this embodiment, to address the problem that while current ELISA plates on the market can accommodate multiple sets of sample cups arranged side-by-side, during actual operation, external force or vibration during transfer can easily cause the sample cups to shake. Because existing ELISA plates lack an effective fixing structure, liquid can easily spill during shaking, leading to sample loss and potential cross-contamination, affecting the accuracy and reliability of experimental results. This invention discloses an ELISA plate holder and an ELISA plate with the holder.

[0025] The plate includes an enzyme-labeled plate body 1, which has multiple placement slots 2 inside. Each placement slot 2 contains a row of sample cups 3. Limiting components are provided on the front and rear sides of the enzyme-labeled plate body 1.

[0026] The limiting component includes two fixing rods 4, both of which are fixedly installed on the surface of the enzyme-labeled plate body 1. A baffle 5 is fixedly provided at the end of each fixing rod 4 away from the enzyme-labeled plate body 1. First limiting plates 6 are fixedly provided at both ends of the sample cups 3. Limiting holes 7 are provided on the surface of each of the two first limiting plates 6. Second limiting plates 8 are slidably provided on the outside of the two fixing rods 4. Limiting posts 9 that are adapted to the limiting holes 7 are fixedly provided on the surface of the second limiting plates 8. Springs 10 are sleeved on the outside of each of the two fixing rods 4.

[0027] Specifically: Two fixing rods 4 are symmetrically distributed in parallel and are fixed to the front and rear end surfaces of the enzyme-labeled plate body 1 by welding or bolts, with their axes perpendicular to the arrangement direction of the sample cups 3. The baffle 5 adopts a rectangular flat plate structure with a side length greater than the outer diameter of the fixing rod 4, and is used to limit the sliding stroke of the second limiting plate 8. The first limiting plate 6 is a long strip of metal plate or engineering plastic plate, which is vertically fixed to the front and rear end surfaces of the sample cups 3. The limiting hole 7 is circular or waist-shaped, with a diameter slightly larger than the outer diameter of the fixing rod 4, ensuring that the first limiting plate 6 can slide freely along the fixing rod 4. The limiting post 9 is a cylindrical protrusion structure, coaxially set with the limiting hole 7, and its diameter is clearance-fitted with the inner diameter of the limiting hole 7 to ensure the locking effect after insertion. The spring 10 is a compression spring 10. In the initial state, one end is pressed against the surface of the enzyme-labeled plate body 1, and the other end is pressed against the inner side of the second limiting plate 8, providing continuous reset elastic force.

[0028] The entire row of sample cups 3 includes multiple independent sample cups 11. Each independent sample cup 11 has a locking plate 12 and a buckle plate 13 fixedly installed on its front and rear sides, respectively. The buckle plate 13 is connected to the adjacent locking plate 12 by a snap-fit ​​connection.

[0029] Specifically, when adjacent independent sample cups 11 come together, the wedge-shaped surface of the buckle plate 13 pushes the barb of the locking plate 12 to elastically deform until the buckle plate 13 is fully embedded in the slot, forming a self-locking snap connection.

[0030] A pressing block 14 is fixedly installed on the outside of the second limiting plate 8, the spring 10 is located between the enzyme labeling plate body 1 and the pressing block 14, and the baffle 5 is located between the second limiting plate 8 and the pressing block 14.

[0031] Each placement slot 2 has multiple limiting slots 15 inside, and the bottom of each individual sample cup 11 is respectively placed in the corresponding limiting slot 15;

[0032] Specifically, the limiting groove 15 is a circular groove with the same number of rows and columns as the number of sample cups 3 arranged in the whole row. The edge of the groove is chamfered to facilitate the insertion and removal of sample cups.

[0033] Below the ELISA plate body 1, there is also a support body 16, which includes four independently placed plates 17.

[0034] Each of the four independently placed plates 17 has a fixed limiting frame 18 on its top, and the enzyme labeling plate body 1 is inserted into the corresponding limiting frame 18.

[0035] Specifically, the limiting frame 18 is used to limit the position of the ELISA plate body 1 to prevent movement and shaking.

[0036] The specific working principle is as follows: The groove 2 inside the ELISA plate body 1 accommodates a row of sample cups 3. The bottom of each independent sample cup 11 is attached to the corresponding circular limiting groove 15. The chamfered edge of the groove facilitates picking and placing and provides initial positioning and support from the bottom. Adjacent independent sample cups 11 are connected by the wedge-shaped surface of the buckle plate 13 pushing the barb of the locking plate 12 to elastically deform and embed into the slot to form a self-locking buckle connection, so that multiple sample cups become a whole and reduce relative shaking. Two fixing rods 4 are symmetrically fixed to the surface of the front and rear limiting components of the ELISA plate body 1, with their axes perpendicular to the sample cup arrangement direction. A baffle 5 restricts the sliding stroke of the second limiting plate 8. A first limiting plate 6 is vertically fixed to the front and rear ends of the entire row of sample cups 3, with the limiting hole 7 slightly larger than the outer diameter of the fixing rods 4. A limiting post 9 is coaxial with the limiting hole 7 and has a clearance fit. A spring 10 initially presses against the inner side of the ELISA plate body 1 and the second limiting plate 8, providing a reset elastic force. During initial locking, the spring 10's elastic force causes the limiting post 9 to insert into the limiting hole 7, locking the entire row of sample cups 3 within the placement slot 2 and restricting its forward and backward movement. When unlocking, pressing the pressing block 14 pushes the second limiting plate 8 to compress the spring 10, causing the limiting post 9 to disengage from the limiting hole 7. After release, the spring 10 resets, causing the limiting post 9 to re-insert into the limiting hole 7 and lock. A support body 16 with four independently placed plates 17 and a top limiting frame 18 is inserted into the ELISA plate body 1, restricting its movement from the bottom and sides to prevent shaking and enhance overall stability. The overall workflow is as follows: When installing sample cups, the individual sample cups 11 are snapped together and placed into the placement slot 2 so that the bottom fits against the limiting slot 15. When locking the sample cups, the spring 10 causes the limiting post 9 to automatically insert into the limiting hole 7 for fixation. When placing the ELISA plate, it is inserted into the limiting frame 18 for limitation. During transfer and operation, the limiting component and the support body 16 work together to prevent the sample cups from shaking and avoid liquid spillage and contamination. When changing sample cups, press the pressing block 14 to unlock and remove the old sample cup. After placing the new sample cup, release the pressing block 14 to reset and lock.

[0037] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus.

[0038] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. An enzyme-linked immunosorbent assay (ELISA) plate holder and an ELISA plate having the holder, comprising an ELISA plate body (1), characterized in that: The enzyme label plate body (1) has multiple placement slots (2) inside, and each placement slot (2) has a row of sample cups (3) inside. The enzyme label plate body (1) has limiting components on both the front and rear sides. The limiting component includes two fixing rods (4), both fixing rods (4) are fixedly installed on the surface of the enzyme labeling plate body (1), and baffles (5) are fixedly provided at the ends of the two fixing rods (4) away from the enzyme labeling plate body (1). First limiting plates (6) are fixedly provided at both ends of the entire sample cup (3), and limiting holes (7) are opened on the surfaces of the two first limiting plates (6). Second limiting plates (8) are slidably provided on the outside of the two fixing rods (4), and limiting posts (9) that are adapted to the limiting holes (7) are fixedly provided on the surface of the second limiting plates (8). Springs (10) are sleeved on the outside of the two fixing rods (4).

2. The enzyme-linked immunosorbent assay (ELISA) plate holder and the ELISA plate having the holder according to claim 1, characterized in that: The array of sample cups (3) includes multiple independent sample cups (11). Each independent sample cup (11) has a locking plate (12) and a buckle plate (13) fixedly installed on its front and rear sides respectively. The buckle plate (13) is connected to the adjacent locking plate (12) by a snap-fit ​​connection.

3. The enzyme-linked immunosorbent assay (ELISA) plate holder and the ELISA plate having the holder according to claim 1, characterized in that: A pressing block (14) is fixedly provided on the outside of the second limiting plate (8), the spring (10) is located between the enzyme label plate body (1) and the pressing block (14), and the baffle (5) is located between the second limiting plate (8) and the pressing block (14).

4. The enzyme-linked immunosorbent assay (ELISA) plate holder and the ELISA plate having the holder according to claim 2, characterized in that: Each of the placement slots (2) has multiple limiting slots (15) inside, and the bottom of each of the independent sample cups (11) is respectively placed in the corresponding limiting slot (15).

5. The enzyme-linked immunosorbent assay (ELISA) plate holder and the ELISA plate having the holder according to claim 1, characterized in that: The ELISA plate body (1) is also provided with a support body (16) directly below it. The support body (16) includes four independently placed plates (17).

6. The enzyme-linked immunosorbent assay (ELISA) plate holder and the ELISA plate having the holder according to claim 5, characterized in that: Each of the four independent placement plates (17) is fixedly provided with a limiting frame (18) on its top, and the enzyme label plate body (1) is inserted into the corresponding limiting frame (18).

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