Eccentric grinding structure and tissue dissociation instrument

Abstract

The utility model belongs to the technical field of test and inspection equipment, and discloses an eccentric grinding structure and a tissue dissociation instrument, a crushing box performs circular motion along the wall surface above a grinding box deviating from the circle center, the crushing box drives a second grinding strip and a scattering block to rotate, and the second grinding strip and a first grinding strip are matched to grind tissues on the side wall of the grinding box; the third grinding strip and the fourth grinding strip are matched to grind the tissue on the bottom surface of the grinding box, the tough tissue can be effectively ground no matter where the tough tissue is located, the grinding efficiency is high, the bottom plate is arranged above the ground, the grinding structure is arranged above the bottom plate, and a crushing box for filtering the tissue is arranged above the bottom plate; a crushing cutter for crushing tissue is arranged in the crushing box, a grinding box for containing the tissue is fixedly arranged on the top face of the bottom plate, a second grinding strip used for grinding the tissue on the side wall of the grinding box is fixedly arranged below the crushing box, and a scattering block used for grinding the tissue on the bottom face of the grinding box is arranged below the second grinding strip.

Description

Technical Field

[0001] This utility model belongs to the technical field of laboratory testing equipment, specifically, it relates to an eccentric grinding structure and a tissue dissociation instrument. Background Technology

[0002] An eccentric grinding structure and tissue dissociation instrument: The eccentric grinding structure is the core component of the tissue dissociation instrument used to achieve mechanical dissociation. It efficiently breaks up tissues and reduces damage to cell viability through planar grinding force.

[0003] The prior art discloses a tissue grinder with a vertical structure (CN202322943684.6), which relates to the field of laboratory testing equipment. The present invention includes a body, and a mounting block is installed at the bottom of the body through a buffer mechanism. A noise reduction mechanism is provided at the bottom of the mounting block.

[0004] Tough tissues are usually difficult to grind, requiring them to be cut into small pieces before grinding. Existing grinding methods are relatively conventional, using a vertical structure to make the test tube holder swing up and down at high frequency, which makes it difficult to grind tough tissues quickly, resulting in low grinding efficiency.

[0005] In view of this, this utility model is proposed. Utility Model Content

[0006] To solve the aforementioned technical problem of low grinding efficiency, the basic concept of the technical solution adopted by this utility model is: an eccentric grinding structure, including a base plate, which is set above the ground;

[0007] The grinding structure is located above the base plate. A crushing box for filtering the tissue is located above the base plate. A crushing blade for crushing the tissue is located inside the crushing box. A grinding box containing the tissue is fixed on the top surface of the base plate. A second grinding strip for grinding the tissue on the side wall of the grinding box is fixed below the crushing box. A loose block for grinding the tissue on the bottom surface of the grinding box is located below the second grinding strip.

[0008] In a preferred embodiment of the present invention, the crushing box has several filter holes inside, and several second grinding strips are arranged in a ring on the bottom surface of the crushing box. One end of each second grinding strip is fixedly connected to the bottom surface of the crushing box, and the other end of each second grinding strip is fixedly connected to the wall surface of the scattered block. The scattered block is a cone, and several third grinding strips are fixedly provided on the bottom surface of the scattered block. The third grinding strips are arranged in a ring.

[0009] In a preferred embodiment of this utility model, the grinding structure further includes a support tube, a transmission rod, and a first servo motor. Each of the three ends of the crushing box is rotatably connected to one end of a transmission rod, the other end of a transmission rod is fixedly connected to the rotating shaft of the first servo motor, the other ends of the other two transmission rods are rotatably connected to one end of a support tube, the other ends of the two support tubes are fixedly connected to the top surface of the base plate, and the first servo motor is fixedly mounted on the top surface of the base plate.

[0010] In a preferred embodiment of the present invention, the grinding structure further includes an L-shaped rod and a second servo motor. One end of the L-shaped rod is fixed to the outer wall of the crushing box, and one end of the crushing blade is rotatably connected to the other end of the L-shaped rod. The second servo motor is fixed to the top surface of the L-shaped rod, and the rotating shaft of the second servo motor is fixedly connected to one end of the crushing blade.

[0011] In a preferred embodiment of the present invention, the grinding structure further includes a bottom cover, a plurality of first grinding strips are fixedly provided on the wall of the grinding box, an opening is provided on the bottom surface of the grinding box, a hinge is provided at the bottom of the opening, the bottom cover is hinged to the opening through the hinge, the bottom cover is locked to the bottom surface of the grinding box through a latch, and a plurality of fourth grinding strips are fixedly provided in a ring on the bottom surface of the inner wall of the grinding box, and the fourth grinding strips are fixedly connected to the grinding box.

[0012] In a preferred embodiment of the present invention, a baffle is fixedly provided on the top surface of the crushing box, the end of the crushing blade passes through the baffle and is rotatably connected to the baffle, a feed inlet is provided on the top surface of the baffle, and a cover is provided above the feed inlet.

[0013] In a preferred embodiment of the present invention, a retaining ring is provided on the top surface of the base plate, a protective cover is provided above the retaining ring, the protective cover engages with the retaining ring, and a side plate is provided on one side of the base plate and is fixedly connected to the side plate.

[0014] A tissue dissociation apparatus includes a dissociation apparatus body, wherein the dissociation apparatus body is provided with all of the above-mentioned eccentric grinding structures, the dissociation apparatus body includes a main body, an insulated box and a guide body, and the bottom surface of the side plate is fixedly connected to the top surface of the main body.

[0015] Compared with the prior art, the present invention has the following advantages:

[0016] 1. The crushing box moves in a circular motion off-center along the wall above the grinding box. The crushing box drives the second grinding strip and the scattered blocks to rotate. The second grinding strip and the first grinding strip work together to grind the structure on the side wall of the grinding box. The third grinding strip and the fourth grinding strip work together to grind the structure on the bottom surface of the grinding box. No matter where the tough structure is located, it can be effectively ground, and the grinding efficiency is high.

[0017] 2. The crushing blade rotates to break down large pieces of tough material. When the material is broken down to a certain extent, the crushing box shakes continuously, and small pieces of tough material fall through the filter holes onto the loose material. They slide down the conical wall of the loose material into the crushing box, where the tough material is evenly distributed. This even distribution increases the grinding area and allows for rapid grinding.

[0018] The specific embodiments of this utility model will be described in further detail below with reference to the accompanying drawings. Attached Figure Description

[0019] In the attached diagram:

[0020] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0021] Figure 2 This is a schematic diagram of the grinding structure of this utility model;

[0022] Figure 3 This is a schematic diagram of the crushing box of this utility model;

[0023] Figure 4 This is a schematic diagram of the second grinding bar of this utility model;

[0024] Figure 5 This is a schematic diagram of the scattered block of this utility model;

[0025] Figure 6 This is a schematic diagram of the grinding box of this utility model.

[0026] In the diagram: 1. Protective cover; 2. Side plate; 3. Base plate; 4. Snap ring; 5. Grinding box; 6. Crushing box; 7. First grinding strip; 8. Support tube; 9. Transmission rod; 10. First servo motor; 11. L-bar; 12. Second servo motor; 13. Crushing blade; 14. Second grinding strip; 15. Scattered block; 16. Third grinding strip; 17. Fourth grinding strip; 18. Baffle; 19. Bottom cover. Detailed Implementation

[0027] To make the objectives, technical solutions, and advantages of the embodiments of this utility model clearer, the technical solutions in the embodiments will be clearly and completely described below with reference to the accompanying drawings. The following embodiments are used to illustrate this utility model.

[0028] An eccentric grinding structure, such as Figure 1 , Figure 3 , Figure 4 , Figure 5 and Figure 6As shown, a base plate 3 is positioned above the ground. A grinding structure is positioned above the base plate 3. A crushing box 6 for filtering the material is positioned above the base plate 3. A crushing blade 13 for crushing the material is positioned inside the crushing box 6. A grinding box 5 containing the material is fixed to the top surface of the base plate 3. A second grinding strip 14 for grinding the material on the side wall of the grinding box 5 is fixed to the bottom surface of the grinding box 6. A scattered block 15 for grinding the material on the bottom surface of the grinding box 5 is positioned below the second grinding strip 14. A support tube 8, a transmission rod 9, and a first servo motor 10 are also present. Each of the three ends of the crushing box 6 is rotatably connected to one end of a transmission rod 9. The other end of one transmission rod 9 is fixedly connected to the rotating shaft of the first servo motor 10. The other two transmission rods 9... The other end of each is rotatably connected to one end of a support tube 8, and the other end of the two support tubes 8 is fixedly connected to the top surface of the base plate 3. The first servo motor 10 is fixedly mounted on the top surface of the base plate 3. The grinding structure also includes a bottom cover 19. Several first grinding strips 7 are fixedly mounted on the wall of the grinding box 5. An opening is opened on the bottom surface of the grinding box 5. A hinge is provided at the bottom of the opening. The bottom cover 19 is hinged to the opening through the hinge. The bottom cover 19 is locked to the bottom surface of the grinding box 5 through a latch. Several fourth grinding strips 17 are fixedly mounted in a ring on the bottom surface of the inner wall of the grinding box 5. The fourth grinding strips 17 are fixedly connected to the grinding box 5. The scattered block 15 is a cone. Several third grinding strips 16 are fixedly mounted on the bottom surface of the scattered block 15. The third grinding strips 16 are distributed in a ring.

[0029] Turn on the power to the first servo motor 10. The first servo motor 10 drives one of the transmission rods 9 to rotate. The transmission rod 9 pulls one end of the crushing box 6. The crushing box 6 rotates with the transmission rod 9, and the other two transmission rods 9 rotate accordingly. The crushing box 6 moves in a circular motion off-center along the wall above the grinding box 5. The crushing box 6 drives the second grinding strip 14 and the scattered block 15 to rotate. The second grinding strip 14 and the first grinding strip 7 work together to grind the tissue on the side wall of the grinding box 5. The third grinding strip 16 and the fourth grinding strip 17 work together to grind the tissue on the bottom surface of the grinding box 5. No matter where the tough tissue is located, it can be effectively ground. The grinding efficiency is high. After grinding, open the latch and open the bottom cover 19. Brush the ground tissue from the opening into the test tube.

[0030] An eccentric grinding structure, such as Figure 1 and Figure 3As shown, the crushing box 6 has several filter holes inside. There are several second grinding strips 14 arranged in a ring on the bottom surface of the crushing box 6. One end of each second grinding strip 14 is fixedly connected to the bottom surface of the crushing box 6, and the other end of each second grinding strip 14 is fixedly connected to the wall of the scattered block 15. The grinding structure also includes an L-rod 11 and a second servo motor 12. One end of the L-rod 11 is fixedly mounted on the outer wall of the crushing box 6, and one end of the crushing blade 13 is rotatably connected to the other end of the L-rod 11. The second servo motor 12 is fixedly mounted on the top surface of the L-rod 11, and the rotating shaft of the second servo motor 12 is fixedly connected to one end of the crushing blade 13. A baffle 18 is fixedly mounted on the top surface of the crushing box 6. The end of the crushing blade 13 passes through the baffle 18 and is rotatably connected to the baffle 18. A feed inlet is opened on the top surface of the baffle 18, and a cover is provided above the feed inlet.

[0031] Open the cover above the feed inlet and put the large pieces of tough material into the crushing box 6. Turn on the power of the second servo motor 12, and the crushing blade 13 will rotate to crush the large pieces of tough material. When it is crushed to a certain extent, the crushing box 6 shakes continuously, and the small pieces of tough material fall through the filter holes onto the loose block 15. They slide down the conical wall of the loose block 15 into the crushing box 6. The tough material is evenly distributed on the grinding box 5. The even distribution can increase the grinding area and be ground quickly.

[0032] An eccentric grinding structure, such as Figure 1 As shown, a retaining ring 4 is provided on the top surface of the base plate 3, and a protective cover 1 is provided above the retaining ring 4. The protective cover 1 is engaged with the retaining ring 4. A side plate 2 is provided on one side of the base plate 3 and is fixedly connected to the side plate 2.

[0033] After placing the tissue into the fragmentation box 6, the protective cover 1 is snapped into the retaining ring 4 to prevent dust from affecting the tissue.

[0034] A tissue dissociation apparatus includes a dissociation apparatus body, which includes a main body, an insulated box, and a guide body. The bottom surface of the side plate (2) is fixedly connected to the top surface of the main body, the guide body is fixedly connected to the insulated box, and the insulated box is slidably connected to the top of the main body. It is worth noting that the main body, the insulated box, and the guide body have been disclosed in a fully automatic tissue dissociation apparatus (CN202421082261.8), and the specific implementation method will not be described in detail here.

[0035] The working principle of this utility model is as follows: Open the cover above the feed inlet and put large pieces of tough tissue into the crushing box 6. Turn on the power of the second servo motor 12, and the crushing blade 13 will rotate to crush the large pieces of tough tissue. When it is crushed to a certain extent, the crushing box 6 will shake continuously, and small pieces of tough tissue will fall through the filter holes onto the scattering block 15. They will slide down the conical wall of the scattering block 15 into the crushing box 6. The tough tissue will be evenly distributed on the grinding box 5. Even distribution can increase the grinding area and allow for rapid grinding. After the tissue is put into the crushing box 6, the protective cover 1 will be locked into the retaining ring 4 to prevent dust from affecting the tissue. Turn on the power of the first servo motor 10. One of the transmission rods 9 is driven to rotate, which pulls one end of the crushing box 6. The crushing box 6 rotates with the transmission rod 9, and the other two transmission rods 9 rotate accordingly. The crushing box 6 moves in a circular motion off-center along the wall above the grinding box 5. The crushing box 6 drives the second grinding strip 14 and the scattered block 15 to rotate. The second grinding strip 14 and the first grinding strip 7 work together to grind the tissue on the side wall of the grinding box 5. The third grinding strip 16 and the fourth grinding strip 17 work together to grind the tissue on the bottom surface of the grinding box 5. No matter where the tough tissue is located, it can be effectively ground, and the grinding efficiency is high. After grinding, the latch is opened, the bottom cover 19 is opened, and the ground tissue is brushed into the test tube from the opening.

[0036] It is understood that this utility model has been described through some embodiments, and those skilled in the art will recognize that various changes or equivalent substitutions can be made to these features and embodiments without departing from the spirit and scope of this utility model. Furthermore, under the teachings of this utility model, these features and embodiments can be modified to adapt to specific situations and materials without departing from the spirit and scope of this utility model. Therefore, this utility model is not limited to the specific embodiments disclosed herein, and all embodiments falling within the scope of the claims of this application are within the protection scope of this utility model.

Claims

1. An eccentric grinding structure, characterized in that, include The base plate (3) is set above the ground; The grinding structure is set above the base plate (3). A crushing box (6) for filtering the tissue is set above the base plate (3). A crushing knife (13) for crushing the tissue is set inside the crushing box (6). A grinding box (5) for storing tissue is fixed on the top surface of the base plate (3). A second grinding strip (14) for grinding the tissue on the side wall of the grinding box (5) is fixed below the crushing box (6). A scattered block (15) for grinding the tissue on the bottom surface of the grinding box (5) is set below the second grinding strip (14).

2. The eccentric grinding structure according to claim 1, characterized in that, The crushing box (6) has several filter holes inside. There are several second grinding strips (14) arranged in a ring on the bottom surface of the crushing box (6). One end of each second grinding strip (14) is fixedly connected to the bottom surface of the crushing box (6), and the other end of each second grinding strip (14) is fixedly connected to the wall surface of the scattered block (15). The scattered block (15) is a cone. Several third grinding strips (16) are fixedly provided on the bottom surface of the scattered block (15). The third grinding strips (16) are arranged in a ring.

3. The eccentric grinding structure according to claim 2, characterized in that, The grinding structure also includes a support tube (8), a transmission rod (9) and a first servo motor (10). The three ends of the crushing box (6) are rotatably connected to one end of a transmission rod (9), the other end of a transmission rod (9) is fixedly connected to the rotating shaft of the first servo motor (10), the other ends of the other two transmission rods (9) are rotatably connected to one end of a support tube (8), the other ends of the two support tubes (8) are fixedly connected to the top surface of the base plate (3), and the first servo motor (10) is fixedly mounted on the top surface of the base plate (3).

4. The eccentric grinding structure according to claim 3, characterized in that, The grinding process also includes an L-bar (11) and a second servo motor (12). One end of the L-bar (11) is fixed to the outer wall of the crushing box (6), and one end of the crushing blade (13) is rotatably connected to the other end of the L-bar (11). The second servo motor (12) is fixed to the top surface of the L-bar (11), and the rotation shaft of the second servo motor (12) is fixedly connected to one end of the crushing blade (13).

5. The eccentric grinding structure according to claim 4, characterized in that, The grinding structure also includes a bottom cover (19), and a number of first grinding strips (7) are fixedly provided on the wall of the grinding box (5). An opening is provided on the bottom surface of the grinding box (5), and a hinge is provided at the bottom of the opening. The bottom cover (19) is hinged to the opening through the hinge. The bottom cover (19) is locked to the bottom surface of the grinding box (5) through a buckle. A number of fourth grinding strips (17) are fixedly provided in a ring on the bottom surface of the inner wall of the grinding box (5). The fourth grinding strips (17) are fixedly connected to the grinding box (5).

6. The eccentric grinding structure according to claim 5, characterized in that, The top surface of the crushing box (6) is fixedly provided with a baffle (18), the end of the crushing blade (13) passes through the baffle (18) and is rotatably connected to the baffle (18), the top surface of the baffle (18) is provided with a feed inlet, and a cover is provided above the feed inlet.

7. The eccentric grinding structure according to claim 6, characterized in that, The bottom plate (3) has a retaining ring (4) on its top surface. A protective cover (1) is provided above the retaining ring (4). The protective cover (1) is engaged with the retaining ring (4). A side plate (2) is provided on one side of the bottom plate (3) and is fixedly connected to the side plate (2).

8. A tissue dissociation apparatus, comprising an apparatus body, characterized in that, The dissociation apparatus body is provided with an eccentric grinding structure as described in any one of claims 1-7. The dissociation apparatus body includes a main body, an insulation box and a guide body, and the bottom surface of the side plate (2) is fixedly connected to the top surface of the main body.

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