Rapid cell microscopic image acquisition device based on biotechnology

Abstract

The utility model relates to the technical field of medical instruments, and discloses a biotechnology cell microscopic image rapid acquisition device, which comprises an acquisition device body, a clamping mechanism comprises a clamping guide block, the outer part of the bottom of the clamping guide block is fixedly connected to the inner top of the acquisition device body, and the outer part of the bottom of the clamping guide block is fixedly connected to the inner top of the acquisition device body. A plurality of clamping blocks are slidably connected to the interior of the clamping guide block, a rotating shaft is rotatably connected to the interior of the clamping guide block, a connecting block is fixedly connected to the exterior of the bottom of the rotating shaft, and a linkage block is rotatably connected to the bottom of the connecting block. According to the utility model, the two electric push rods fixed in the collector body through the mounting blocks are started, the two sliding blocks are pushed to get close to each other through the electric push rods, so that the two clamping blocks fixedly connected with the sliding blocks are driven to slide, and the two clamping blocks are driven to slide through the cooperation of the linkage blocks rotatably connected to the bottoms of the clamping blocks and the connecting blocks; and the four clamping blocks are driven to slide synchronously.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, and in particular to a rapid acquisition device for biotechnology cell microscopic images. Background Technology

[0002] The acquisition of biochemical cell microscopic images typically relies on microscopy techniques such as optical microscopy, electron microscopy, and confocal microscopy. These microscopes magnify cells and their internal structures, allowing researchers to observe characteristics such as cell morphology, size, distribution, and functional state. The purpose of cell image acquisition is to gain a deeper understanding of the biological characteristics, functional mechanisms, and responses of cells under different environments. This is crucial for fields such as biomedical research, disease diagnosis, and drug development, helping to reveal key information such as cell behavior, pathological changes, and molecular processes. Through high-resolution microscopic images, researchers can more accurately analyze the dynamic changes of cells, thereby promoting the development and innovation of biotechnology.

[0003] Rapid cell microscopy image acquisition devices in biotechnology typically integrate high-resolution microscopes, automated acquisition systems, and image processing software. These devices convert real-time cell images into digital signals using high-speed cameras and optical sensors, rapidly capturing changes in cells under different times and conditions. In terms of working principle, the devices utilize optical or laser scanning technology to image cells, while simultaneously employing an automated platform to precisely adjust parameters such as microscope focal length and image exposure time to obtain high-quality cell images. Image processing algorithms then rapidly extract key cell features and perform real-time analysis. These devices improve the efficiency and accuracy of cell image acquisition and are widely used in research fields such as cell biology and drug screening.

[0004] In existing technologies, some rapid acquisition devices for biotechnological cell microscopy images are susceptible to external factors, causing the culture dish to shake during the acquisition process. This shaking typically originates from equipment vibration, improper operation, or environmental factors. Shaking can lead to microscope focus misalignment or image blurring, thus affecting the clarity and quality of cell images. Ultimately, this can affect the accuracy of image analysis and even lead to erroneous biological conclusions, especially when performing dynamic cell observation or high-resolution imaging. Therefore, this paper proposes a rapid acquisition device for biotechnological cell microscopy images to address these issues. Utility Model Content

[0005] To overcome the above shortcomings, this utility model provides a rapid acquisition device for biotechnology cell microscopic images, which aims to improve the problem that some existing rapid acquisition devices for biotechnology cell microscopic images are affected by the shaking of the culture dish during the acquisition process due to external factors, thus affecting the final acquisition effect.

[0006] To achieve the above objectives, the present invention adopts the following technical solution: a rapid acquisition device for biotechnology cell microscopic images, comprising an acquisition body, a support frame fixedly connected to the top of the acquisition body, a collection camera fixedly connected to the bottom of the support frame, a clamping mechanism fixedly connected inside the acquisition body, a heat preservation mechanism fixedly connected inside the acquisition body, a top cover slidably connected inside the acquisition body, a sealing ring fixedly connected to the outside of the top cover, and two lifting blocks fixedly connected to the top of the top cover;

[0007] The clamping mechanism includes a clamping guide block, the bottom of which is fixedly connected to the top of the inside of the collector body. Multiple clamping blocks are slidably connected inside the clamping guide block. A rotating shaft is rotatably connected inside the clamping guide block. A connecting block is fixedly connected to the bottom of the rotating shaft. A linkage block is rotatably connected to the bottom of the connecting block. The top of the linkage block is rotatably connected to the bottom of the clamping block. A drive assembly is fixedly connected to the bottom of the clamping block.

[0008] As a further description of the above technical solution: the heat preservation mechanism includes a temperature sensor, the temperature sensor is fixedly connected to the outside of the collector body, a heating tube is fixedly connected to the inside of the collector body, one end of the heating tube is fixedly connected to a controller, a power cord is fixedly connected to the outside of the controller, the other end of the heating tube is fixedly connected to the inside of the collector body, and a protective block is slidably connected to the inside of the collector body.

[0009] As a further description of the above technical solution: the drive assembly includes two mounting blocks, the outside of which is fixedly connected to the inside of the collector body, and an electric push rod is fixedly connected inside the mounting block. Both ends of the electric push rod are fixedly connected to sliding blocks, and the tops of the two sliding blocks are fixedly connected to the bottom of the clamping block.

[0010] As a further description of the above technical solution: a culture dish is slidably connected to one side of a plurality of clamping blocks, a culture cap is rotatably connected to the outside of the culture dish, and a plurality of friction blocks are provided on the outside of the culture cap;

[0011] As a further description of the above technical solution: guide grooves are provided inside both sides of the clamping block, a guide block is provided inside the clamping guide block, and the outside of the guide block is slidably connected to the inside of the guide groove;

[0012] As a further description of the above technical solution: a sliding groove is provided inside the collector body, and the outside of the sliding block is slidably connected to the inside of the sliding groove;

[0013] As a further description of the above technical solution: the inside of the collector body is provided with a mounting groove, and the heating tube is externally fixedly connected to the inside of the mounting groove;

[0014] As a further description of the above technical solution: an adjustment groove is provided inside the rear side of the collector body, and the outside of the protective block is slidably connected to the inside of the adjustment groove.

[0015] This utility model has the following beneficial effects:

[0016] 1. In this utility model, two electric push rods fixed inside the collector body by the mounting block are activated. The electric push rods push two sliding blocks closer to each other, thereby causing two clamping blocks fixedly connected to the sliding blocks to slide. During the sliding of the clamping blocks, the linkage block and connecting block connected to the bottom of the clamping block are rotated to drive the four clamping blocks to slide synchronously, thereby ensuring the stability of the petri dish during the image collection process and improving the quality of the image collection results.

[0017] 2. In this utility model, a temperature sensor located inside the collector body detects the internal temperature of the collector body. When the internal temperature of the collector body is detected to be lower than the cell activity temperature, power is supplied to the controller through the power cord, and the controller is activated. The controller heats the heating tube and heats the internal temperature of the collector body through heat insulation, thereby ensuring that the internal temperature of the collector body is maintained at the cell activity temperature, thereby improving the quality of cells and ultimately improving the quality of image collection. Attached Figure Description

[0018] Figure 1 This is a three-dimensional schematic diagram of a rapid acquisition device for biotechnology cell microscopic images proposed in this utility model;

[0019] Figure 2 This is a schematic diagram of the lifting block of a rapid acquisition device for biotechnology cell microscopic images proposed in this utility model;

[0020] Figure 3 This is a schematic diagram of the clamping block of a rapid acquisition device for biotechnology cell microscopic images proposed in this utility model;

[0021] Figure 4 This is a schematic diagram of the linkage block of a rapid acquisition device for biotechnology cell microscopic images proposed in this utility model.

[0022] Legend:

[0023] 1. Collector body; 2. Top cover; 3. Lifting block; 4. Support frame; 5. Collecting camera; 6. Sealing ring; 7. Temperature sensor; 8. Heating tube; 9. Controller; 10. Protective block; 11. Power cord; 12. Electric push rod; 13. Sliding block; 14. Mounting block; 15. Clamping guide block; 16. Clamping block; 17. Connecting block; 18. Linkage block; 19. Rotating shaft; 20. Petri dish; 21. Culture cover. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0025] Reference Figure 1 , Figure 3 , Figure 4 This utility model provides an embodiment of a rapid acquisition device for biotechnology cell microscopic images, including an acquisition body 1, which is the main structure of the entire device and has sufficient strength to withstand various operations and external influences. A support frame 4 is fixedly connected to the top of the acquisition body 1. The support frame 4 is located at the top of the acquisition body 1 and plays a supporting and fixing role. A collecting camera 5 is fixedly connected to the bottom of the support frame 4. The collecting camera 5 is fixed to the bottom of the support frame 4 and is mainly used to acquire cell images. A clamping mechanism is fixedly connected inside the acquisition body 1. The clamping mechanism is used to fix and clamp the culture dish 20. A heat preservation mechanism is fixedly connected inside the acquisition body 1. The heat preservation mechanism is designed to maintain the temperature inside the cell culture dish 20 and ensure that the growth environment of the cells is stable during the image acquisition process. A top cover 2 is slidably connected inside the acquisition body 1. The top cover 2 is used to close the upper part of the device to prevent the external environment from interfering with the cell culture process. A sealing ring 6 is fixedly connected to the outside of the top cover 2. Two lifting blocks 3 are fixedly connected to the top of the top cover 2.

[0026] The clamping mechanism includes a clamping guide block 15. The main function of the clamping guide block 15 is to guide the sliding of the clamping block 16, ensure that the clamping force of the clamping block 16 is evenly distributed, and fix the culture dish 20. The bottom of the clamping guide block 15 is fixedly connected to the top of the inside of the collector body 1. Multiple clamping blocks 16 are slidably connected inside the clamping guide block 15. The clamping blocks 16 are connected to the clamping guide block 15 and are responsible for actually clamping the culture dish 20. The clamping block 16 has guide grooves on both sides that slide with the guide blocks to ensure a smooth clamping process. Guide grooves are also provided inside both sides of the clamping block 16. A guide block is located inside the clamping guide block 15. These guide blocks help the clamping block 16 slide smoothly within the guide grooves, reducing friction and ensuring clamping accuracy. The outer side of the guide block is slidably connected to the inside of the guide groove. A rotating shaft 19 is rotatably connected inside the clamping guide block 15. A connecting block 17 is fixedly connected to the bottom of the rotating shaft 19. A linkage block 18 is rotatably connected to the bottom of the connecting block 17. The rotating shaft 19 connects the various components of the clamping mechanism to ensure coordinated movements during clamping. Through the design of the linkage block 18, the clamping block 16 can be adjusted as needed to ensure stable clamping. The top of the linkage block 18 is rotatably connected to the bottom of the clamping block 16. A drive assembly is fixedly connected to the bottom of the clamping block 16. A culture dish 20 is slidably connected to the adjacent side of multiple clamping blocks 16. A culture cap 21 is rotatably connected to the outside of the culture dish 20. The culture dish 20 is used to contain cell culture medium and support cell growth. The culture cover 21 is used to cover the culture dish 20 to prevent the cells from being exposed to the external environment and to ensure stable culture conditions. The culture cover 21 has multiple friction blocks on its exterior.

[0027] The drive assembly includes two mounting blocks 14. The mounting blocks 14 provide fixed support for the electric push rod 12 and ensure the stable operation of the push rod. The external parts of the mounting blocks 14 are fixedly connected to the inside of the collector body 1. The electric push rod 12 is fixedly connected inside the mounting blocks 14. The electric push rod 12 drives the movement of the sliding block 13, thereby controlling the sliding and clamping action of the clamping block 16. The two ends of the electric push rod 12 are fixedly connected to the sliding blocks 13. The sliding blocks 13 achieve smooth movement of the clamping block 16 through sliding connection with the sliding groove. The tops of the two sliding blocks 13 are fixedly connected to the bottom of the clamping block 16. The inside of the collector body 1 is provided with a sliding groove, and the outside of the sliding blocks 13 is slidably connected to the inside of the sliding groove.

[0028] Reference Figure 1 , Figure 2The insulation mechanism includes a temperature sensor 7, which monitors the internal temperature and feeds the data back to the controller 9 to ensure that the device can automatically adjust the temperature. The temperature sensor 7 is externally fixedly connected to the inside of the collector body 1. A heating tube 8 is fixedly connected inside the collector body 1. The heating tube 8 is used to heat the insulation area to keep the internal temperature of the device within a suitable range for cell growth. One end of the heating tube 8 is fixedly connected to the controller 9. The controller 9 receives the data from the temperature sensor 7 and controls the operation of the heating tube 8 to precisely adjust the temperature of the device. A power cord 11 is externally fixedly connected to the controller 9. The other end of the heating tube 8 is fixedly connected inside the collector body 1. A protective block 10 is slidably connected inside the collector body 1. The protective block 10 is used to protect the heating tube 8 and the temperature control system, and can also prevent the external environment from interfering with the internal temperature of the device. An installation groove is opened inside the collector body 1. The heating tube 8 is externally fixedly connected inside the installation groove. An adjustment groove is opened inside the rear side of the collector body 1. The protective block 10 is externally slidably connected inside the adjustment groove.

[0029] Working principle: The two lifting blocks 3 on the top of the top cover 2 facilitate the opening of the top cover 2, while the sealing ring 6 on the outside of the top cover 2 provides a sealed space inside the collector body 1, thereby reducing the influence of the external environment on cell image collection.

[0030] The two electric push rods 12, which are fixed inside the collector body 1 by the mounting block 14, are activated. The electric push rods 12 push the two sliding blocks 13 closer to each other, thereby causing the two clamping blocks 16, which are fixedly connected to the sliding blocks 13, to slide. During the sliding of the clamping blocks 16, the four clamping blocks 16 slide synchronously with the cooperation of the linkage block 18 and the connecting block 17 connected to the bottom of the clamping blocks 16, thereby ensuring the stability of the culture dish 20 during the image collection process and improving the quality of the image collection results.

[0031] Temperature sensor 7, located inside the collector body 1, detects the internal temperature of the collector body 1. When the internal temperature of the collector body 1 is detected to be lower than the cell activity temperature, power is supplied to the controller 9 through the power cord 11. The controller 9 is then activated and heats the heating tube 8. The internal temperature of the collector body 1 is heated by heat insulation, thereby ensuring that the internal temperature of the collector body 1 is maintained at the cell activity temperature, thus improving the quality of the cells and ultimately improving the quality of image collection. Finally, the cells inside the culture dish 20 are captured and collected by the collection camera 5 at the bottom of the support frame 4.

[0032] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A rapid acquisition device for biotechnology cell microscopic images, comprising an acquisition unit (1), characterized in that: The top of the collector body (1) is fixedly connected to a support frame (4), the bottom of the support frame (4) is fixedly connected to a collecting camera (5), the inside of the collector body (1) is fixedly connected to a clamping mechanism, the inside of the collector body (1) is fixedly connected to a heat preservation mechanism, the inside of the collector body (1) is slidably connected to a top cover (2), the outside of the top cover (2) is fixedly connected to a sealing ring (6), and the top of the top cover (2) is fixedly connected to two lifting blocks (3). The clamping mechanism includes a clamping guide block (15), the bottom of which is fixedly connected to the top of the inside of the collector body (1). Multiple clamping blocks (16) are slidably connected inside the clamping guide block (15). A rotating shaft (19) is rotatably connected inside the clamping guide block (15). A connecting block (17) is fixedly connected to the bottom of the rotating shaft (19). A linkage block (18) is rotatably connected to the bottom of the connecting block (17). The top of the linkage block (18) is rotatably connected to the bottom of the clamping block (16). A drive assembly is fixedly connected to the bottom of the clamping block (16).

2. The rapid acquisition device for biotechnology cell microscopic images according to claim 1, characterized in that: The heat preservation mechanism includes a temperature sensor (7), which is externally fixedly connected to the inside of the collector body (1). A heating tube (8) is fixedly connected inside the collector body (1). A controller (9) is fixedly connected to one end of the heating tube (8). A power cord (11) is fixedly connected to the outside of the controller (9). The other end of the heating tube (8) is fixedly connected inside the collector body (1). A protective block (10) is slidably connected inside the collector body (1).

3. The rapid acquisition device for biotechnology cell microscopic images according to claim 1, characterized in that: The drive assembly includes two mounting blocks (14), the outside of which is fixedly connected to the inside of the collector body (1), and an electric push rod (12) is fixedly connected inside the mounting block (14). Sliding blocks (13) are fixedly connected to both ends of the electric push rod (12), and the tops of the two sliding blocks (13) are fixedly connected to the bottom of the clamping block (16).

4. The rapid acquisition device for biotechnology cell microscopic images according to claim 1, characterized in that: A culture dish (20) is slidably connected to one side of a plurality of clamping blocks (16), and a culture cap (21) is rotatably connected to the outside of the culture dish (20), and a plurality of friction blocks are provided on the outside of the culture cap (21).

5. The rapid acquisition device for biotechnology cell microscopic images according to claim 1, characterized in that: The clamping block (16) has guide grooves on both sides, and the clamping guide block (15) has a guide block inside. The outside of the guide block is slidably connected to the inside of the guide groove.

6. The rapid acquisition device for biotechnology cell microscopic images according to claim 3, characterized in that: The collector body (1) has a sliding groove inside, and the sliding block (13) is externally slidably connected to the inside of the sliding groove.

7. The rapid acquisition device for biotechnology cell microscopic images according to claim 2, characterized in that: The collector body (1) has an internal mounting groove, and the heating tube (8) is externally fixedly connected to the inside of the mounting groove.

8. The rapid acquisition device for biotechnology cell microscopic images according to claim 2, characterized in that: An adjustment groove is provided inside the rear side of the collector body (1), and the outside of the protective block (10) is slidably connected to the inside of the adjustment groove.

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