A chromatographic column that is easily disassembled

Abstract

This application relates to a disassembleable chromatographic column, specifically a liquid chromatography column. The column includes a column tube with caps threaded to both ends. Sealing plugs are detachably installed at both ends of the column tube, penetrating the caps and extending to their outer sides. A portion of the sealing plug extends into an opening at the end of the column tube. A filter element is installed within the mounting cavity. An axial through-hole is formed in the middle of the sealing plug. A rubber joint is fitted onto the end of the sealing plug extending beyond the caps. Both ends of the opening communicate with the rubber joint and the mounting cavity, respectively. A sealing structure is installed on the outer wall of the portion of the sealing plug extending into the opening of the column tube, sealing the space between the inner wall of the column tube and the sealing plug. This application improves the ease of disassembly and assembly of the chromatographic column for users.

Description

Technical Field

[0001] This application relates to the field of liquid chromatography columns, and more particularly to a chromatographic column that is easy to disassemble. Background Technology

[0002] A chromatographic column, also known as a chromatography column, is a high-efficiency physical separation technique. It is commonly used in analytical chemistry in conjunction with appropriate detection methods. Its principle is to separate the various substances by utilizing the differences in their partition coefficients, adsorption capacities, and other affinities between two phases. As the site and tool for chromatographic separation, the liquid chromatography column plays a decisive role in the separation effect.

[0003] In existing technologies, common chromatographic columns mainly include column tubes (mostly made of stainless steel), packing material, connectors (generally made of stainless steel), ferrules (generally made of stainless steel), pressure caps, sealing rings, filter plates, screws (generally made of stainless steel), connecting pipes (generally made of stainless steel), etc.

[0004] However, in common chromatographic columns, components such as ferrules, pressure caps, sealing rings, and filter plates are all installed separately at both ends of the column tube. When users want to open the end of the chromatographic column to clean the inside, disassembly and assembly are inconvenient and need improvement. Utility Model Content

[0005] To improve the ease of disassembly and assembly of chromatographic columns for operators, this application provides a chromatographic column that is easy to disassemble.

[0006] The chromatographic column that is easy to disassemble provided in this application adopts the following technical solution:

[0007] A disassembleable chromatographic column includes a column tube with caps threaded to both ends. Sealing plugs are detachably installed at the ends of the column tube, penetrating the caps and extending to the outside of the caps. An installation cavity is provided at the end of the sealing plug extending into the column tube, where a filter element is installed. A through hole is axially formed in the middle of the sealing plug. A rubber joint is fitted onto the end of the sealing plug extending beyond the caps. Both ends of the column tube communicate with the rubber joint and the installation cavity, respectively.

[0008] A sealing structure is installed on the outer wall of the portion of the sealing plug that extends into the end port of the column tube. The sealing structure is sealed between the inner wall of the column tube and the sealing plug.

[0009] By adopting the above technical solution, when it is necessary to remove the sealing plugs at both ends of the column tube, the user can unscrew the caps, allowing them to slide away from the column tube until the caps are completely separated from the ends of the column tube. Subsequently, the user can remove the sealing plugs. Since the filter plate is located within the mounting cavity of the sealing plug, the user can remove the filter plate at the same time as removing the sealing plug, effectively improving the ease of assembly and disassembly of the chromatography column. The rubber connectors facilitate the connection of the chromatography column to external tubing during use.

[0010] Preferably, both ends of the column tube are provided with threaded connection parts, the inner side wall of the cap is provided with internal threads, the cap is threadedly installed on the threaded connection parts, and the cap is provided with a through hole for the sealing plug to extend out.

[0011] The sealing plug is integrally formed with a limiting protrusion ring, and the upper and lower sides of the limiting protrusion ring abut against the end of the cap and the threaded connection.

[0012] By adopting the above technical solution, when installing the sealing plug, the limiting protrusion ring can restrict the position of the sealing plug and the position of the cap, which makes it easy for the user to quickly fix the sealing plug to the end of the column tube, while fixing the length of the part of the sealing plug that extends into the column tube.

[0013] Preferably, the mounting cavity includes a mounting portion and a flow guiding portion. The mounting portion is adapted to the shape of the filter element, and the flow guiding portion is arranged in an outwardly expanding tapered shape along the direction away from the limiting protrusion ring. The end of the flow guiding portion away from the filter element is connected to the through hole.

[0014] The inner wall of the mounting cavity extends inward and is provided with an extension portion. The extension portion is located on the side of the mounting portion away from the flow guide portion, and the filter is limited and installed between the flow guide portion and the extension portion.

[0015] By adopting the above technical solution, the flow guide part is arranged in an approximately funnel shape to guide the liquid flowing in through the through hole, so that the liquid is filtered evenly through the filter plate. The extension part restricts the position of the filter plate and can confine the filter plate within the mounting part.

[0016] Preferably, the sealing structure includes two sealing rings, and the sealing plug has two annular grooves. The two sealing rings are respectively embedded in the two annular grooves, and both sealing rings abut against the inner wall of the column tube between the annular grooves.

[0017] By adopting the above technical solution, the two sealing rings are pressed tightly between the inner wall of the column tube and the annular groove, which can provide double sealing protection for the installation of the plug and improve the sealing effect of the sealing plug.

[0018] Preferably, a positioning protrusion is integrally formed on the inner sidewall of the rubber joint, and a positioning platform is provided at the end of the threaded connection part, with the positioning protrusion being engaged on the positioning platform.

[0019] By adopting the above technical solution, and through the combination and use of the positioning protrusion and the positioning platform, users can quickly position the rubber joint.

[0020] Preferably, the outer edge of the end of the threaded connection is provided with a chamfer.

[0021] By adopting the above technical solution, the bevel setting makes it easier for users to quickly insert the threaded connection into the cap when installing the cap.

[0022] In summary, the easily disassembled chromatographic column of this application has at least one of the following beneficial technical effects:

[0023] 1. When it is necessary to remove the sealing plugs at both ends of the column tube, the user can unscrew the cap and slide it away from the column tube until the cap is completely separated from the end of the column tube; then, the user can remove the sealing plug. Since the filter plate is located in the installation cavity inside the sealing plug, the user can remove the filter plate at the same time as removing the sealing plug, which can effectively improve the convenience of the user in disassembling and assembling the chromatography column.

[0024] 2. The guide section is approximately funnel-shaped to guide the liquid flowing in through the through hole, so that the liquid is filtered evenly through the filter plate. The extension section restricts the position of the filter plate and can confine the filter plate within the mounting section. Attached Figure Description

[0025] Figure 1 This is a schematic diagram illustrating the overall structure of the chromatographic column in an embodiment of this application.

[0026] Figure 2 This is a schematic diagram illustrating the internal structure of a chromatographic column in an embodiment of this application.

[0027] Figure 3 This is a schematic diagram illustrating the overall structure of the mounting cavity in an embodiment of this application.

[0028] Explanation of reference numerals in the attached drawings: 1. Column tube; 11. Threaded connection; 2. Cap; 21. Insertion hole; 3. Sealing plug; 31. Mounting cavity; 311. Mounting part; 312. Flow guide part; 32. Through hole; 33. Limiting protrusion ring; 34. Extension part; 35. Positioning platform; 4. Filter plate; 5. Rubber joint; 51. Positioning protrusion ring; 6. Sealing ring. Detailed Implementation

[0029] The following combination Figures 1-2 This application will be described in further detail.

[0030] This application discloses a chromatographic column that is easy to disassemble. (Refer to...) Figure 1 and Figure 2 It mainly includes a column tube 1, which is filled with filler. Caps 2 are threaded to both ends of the column tube 1. Sealing plugs 3 are detachably installed at the ends of the column tube 1. A circular hole is opened through the cap 2 for the sealing plug 3 to pass through. The sealing plug passes through the cap 2 and extends to the outside of the cap 2. An installation cavity 31 is opened at the end of the sealing plug extending into the ends of the column tube 1's ports 3. Filter plates 4 are installed in the installation cavity 31. A through hole 32 is opened axially in the middle of the sealing plug 3. A rubber joint 5 is fitted onto the end of the sealing plug 3 extending out of the cap 2. Both ends of the column tube are connected to the rubber joint 5 and the installation cavity 31, respectively. A sealing structure is installed on the outer wall of the portion of the sealing plug 3 extending into the end port of the column tube 1. The sealing structure is sealed between the inner wall of the column tube 1 and the sealing plug 3.

[0031] When it is necessary to remove the sealing plugs 3 at both ends of the column tube 1, the user can unscrew the cap 2, causing it to slide away from the column tube 1 until the cap 2 is completely separated from the end of the column tube 1. Then, the user can remove the sealing plug 3. Since the filter plate is located in the mounting cavity 31 within the sealing plug 3, the user can remove the filter plate 4 at the same time as removing the sealing plug 3, effectively improving the ease of disassembly and assembly of the chromatography column. The rubber connector 5 facilitates the connection of the chromatography column to external pipelines during use.

[0032] Reference Figure 2 Both ends of the column tube 1 are provided with threaded connection parts 11, and the inner side wall of the cap 2 is provided with internal threads. The cap 2 is threadedly installed on the threaded connection part 11. The cap 2 has a through hole 21 for the sealing plug 3 to extend out. The sealing plug 3 is integrally formed with a limiting protrusion ring 33, and the upper and lower sides of the limiting protrusion ring 33 are pressed between the cap 2 and the end of the threaded connection part 11.

[0033] When the sealing plug 3 is installed, the limiting protrusion 33 can restrict the position of the sealing plug 3 and the position of the cap 2, which makes it easy for the user to quickly fix the sealing plug 3 to the end of the column tube 1, and at the same time fixes the length of the part of the sealing plug 3 that extends into the column tube 1.

[0034] Reference Figure 2 and Figure 3The mounting cavity 31 includes a mounting part 311 and a flow guide part 312. The mounting part 311 is adapted to the shape of the filter element 4. The flow guide part 312 is arranged in an outwardly expanding cone shape in the direction away from the limiting protrusion ring 33. The end of the flow guide part 312 away from the filter element 4 is connected to the through hole 32. An extension part 34 is provided inwardly on the inner wall of the mounting cavity 31. The extension part 34 is located on the side of the mounting part 311 away from the flow guide part 312. The filter element 4 is limited and installed between the flow guide part 312 and the extension part 34.

[0035] The guide portion 312 is arranged in an approximately funnel shape to guide the liquid flowing in through the through hole 32, so that the liquid is filtered evenly through the filter plate. The extension portion 34 restricts the position of the filter plate 4, which can confine the filter plate within the mounting portion 311.

[0036] Reference Figure 2 The sealing structure includes two sealing rings 6. The sealing plug 3 has two annular grooves. The two sealing rings 6 are respectively embedded in the two annular grooves. Both sealing rings 6 are pressed against the inner wall of the column tube 1 between the annular grooves.

[0037] Two sealing rings 6 are pressed tightly between the inner wall of the column tube 1 and the annular groove, which can provide double sealing protection for the installation of the plug and improve the sealing effect of the sealing plug 3.

[0038] Reference Figure 2 A positioning protrusion ring 51 is integrally formed on the inner side wall of the rubber joint 5, and a positioning platform 35 is provided at the end of the threaded connection part 11, with the positioning protrusion ring 51 being engaged on the positioning platform 35.

[0039] By using the positioning protrusion 51 in conjunction with the positioning platform 35, users can quickly position the rubber joint 5.

[0040] Reference Figure 2 The outer edge of the threaded connection part 11 is provided with a bevel. The bevel is provided to facilitate the user to quickly insert the threaded connection part 11 into the cap 2 when installing the cap 2.

[0041] The implementation principle of the easily disassembled chromatographic column proposed in this application embodiment is as follows: When it is necessary to disassemble the sealing plugs 3 at both ends of the column tube 1, the user can screw the cap 2 so that the cap 2 slides away from the column tube 1 until the cap 2 is completely separated from the end of the column tube 1; then, the user can take out the sealing plug 3. Since the filter plate is located in the installation cavity 31 inside the sealing plug 3, the user can take out the filter 4 at the same time as taking out the sealing plug 3, which can effectively improve the convenience of the user in disassembling and assembling the chromatographic column.

[0042] The above are all preferred embodiments of this application and are not intended to limit the scope of protection of this application. Therefore, all equivalent changes made in accordance with the structure, shape and principle of this application should be covered within the scope of protection of this application.

Claims

1. A chromatographic column that is easy to disassemble, characterized in that, The system includes a column tube (1), with caps (2) threaded to both ends of the column tube (1). Sealing plugs (3) are detachably installed at the ends of the column tube (1). The sealing plugs (3) penetrate the caps (2) and extend to the outside of the caps (2). An installation cavity (31) is provided at the end of the sealing plugs (3) that extends into the column tube (1). A filter (4) is installed in the installation cavity (31). A through hole (32) is provided in the middle of the sealing plugs (3) along the axial direction. A rubber joint (5) is fitted at the end of the sealing plugs (3) that extends out of the caps (2). The two ends of the column tube (1) are connected to the rubber joint (5) and the installation cavity (31) respectively. A sealing structure is installed on the outer wall of the portion of the sealing plug (3) that extends into the end port of the column tube (1), and the sealing structure is sealed between the inner wall of the column tube (1) and the sealing plug (3).

2. The easily disassembled chromatographic column according to claim 1, characterized in that, Both ends of the column tube (1) are provided with threaded connection parts (11), the inner side wall of the cap (2) is provided with internal threads, the cap (2) is threadedly installed on the threaded connection part (11), and the cap (2) is provided with a through hole (21) for the sealing plug (3) to extend out. The sealing plug (3) is integrally formed with a limiting protrusion ring (33), and the upper and lower sides of the limiting protrusion ring (33) abut against the end of the cap (2) and the threaded connection (11).

3. The easily disassembled chromatographic column according to claim 2, characterized in that, The mounting cavity (31) includes a mounting part (311) and a flow guide part (312). The mounting part (311) is adapted to the shape of the filter (4). The flow guide part (312) is arranged in an outwardly expanding cone shape in the direction away from the limiting protrusion ring (33). The end of the flow guide part (312) away from the filter (4) is connected to the through hole (32). The inner wall of the mounting cavity (31) is provided with an extension (34) extending inward. The extension (34) is located on the side of the mounting part (311) away from the guide part (312). The filter (4) is limited and installed between the guide part (312) and the extension (34).

4. The easily disassembled chromatographic column according to claim 3, characterized in that, The sealing structure includes two sealing rings (6), and the sealing plug (3) has two annular grooves. The two sealing rings (6) are respectively embedded in the two annular grooves, and the two sealing rings (6) are pressed against the inner wall of the column tube (1) between the annular grooves.

5. A chromatographic column that is easy to disassemble according to claim 4, characterized in that, The inner wall of the rubber joint (5) is integrally formed with a positioning protrusion (51), and the end of the threaded connection part (11) is provided with a positioning platform (35), and the positioning protrusion (51) is engaged on the positioning platform (35).

6. A chromatographic column that is easy to disassemble according to claim 5, characterized in that, The outer edge of the end of the threaded connection (11) is provided with a chamfer.

Images