A cleaning device for anti-clogging injection needles in liquid chromatographs

Abstract

This invention provides a cleaning device for anti-clogging injection needles in liquid chromatographs, comprising: an ultrasonic cleaner; a rinsing assembly for rinsing the anti-clogging injection needles installed on the rear side of the ultrasonic cleaner; a cleaning tank inside the upper side of the ultrasonic cleaner, in which a placement rack is movably placed; multiple fixing brackets for hanging the anti-clogging injection needles are movably placed on the upper side of the placement rack; and the rinsing assembly includes a vertical plate, on the top of which a drive box is fixed. Compared with the prior art, this invention has the following advantages: the ultrasonic cleaner, in conjunction with multiple fixing brackets, can stably clean the anti-clogging injection needles, avoiding affecting the ultrasonic cleaning effect; the rinsing assembly, through multi-liquid rinsing, can thoroughly clean the anti-clogging injection needles after ultrasonic cleaning, and hot water rinsing can avoid the residue of other liquids.

Description

Technical Field

[0001] This utility model belongs to the field of laboratory equipment cleaning technology, and specifically relates to a cleaning device for anti-clogging injection needles of liquid chromatographs. Background Technology

[0002] Existing anti-clogging needle cleaning devices for liquid chromatographs often struggle to completely remove residual substances from the needle's inner wall when dealing with viscous samples or high-molecular-weight precipitates using traditional backflushing and ultrasonic cleaning methods. Incompletely removed viscous samples or high-molecular-weight precipitates accumulate over time, gradually clogging the needle and affecting the instrument's normal operation and the accuracy of experimental results. Furthermore, residual substances can cause cross-contamination, leading to deviations in analytical results between different samples and reducing the reliability of experimental data. These drawbacks primarily stem from the strong adsorption properties of viscous samples, which easily adhere to the needle's inner wall, forming stubborn residues; while high-molecular-weight precipitates further increase the difficulty of cleaning due to intermolecular forces and changes in their physical morphology.

[0003] Conventional solutions include increasing back pressure, extending sonication time, and using strong solvents for cleaning, but these methods all have significant drawbacks. For example, excessively high back pressure may damage the needle or reduce its sealing performance; prolonged sonication is not only inefficient but may also damage the needle material; while strong solvent cleaning is effective, it is costly and may pose environmental pollution risks. Therefore, we aim to design a novel needle cleaning device to address this problem. Utility Model Content

[0004] In view of the shortcomings of the existing technology, the purpose of this utility model is to provide a cleaning device for anti-clogging injection needles for liquid chromatographs, so as to solve the problems mentioned in the background art.

[0005] This utility model is achieved through the following technical solution: a cleaning device for anti-clogging injection needles for liquid chromatographs, comprising: an ultrasonic cleaner, a rinsing component for rinsing the anti-clogging injection needles is installed on the rear side of the ultrasonic cleaner, a cleaning tank is provided inside the upper side of the ultrasonic cleaner and a placement rack is movably placed therein, and multiple fixing racks for hanging anti-clogging injection needles are movably placed on the upper side of the placement rack.

[0006] The rinsing assembly includes a vertical plate, a drive box is fixed to the top of the vertical plate, a rinsing tube for conveying rinsing fluid is installed on the lower front side of the drive box, a lifting platform is movably installed on the lower front side of the vertical plate, a receiving cylinder is movably installed on the upper side of the lifting platform, and a fixing bracket for fixing the anti-clogging injection needle is fixed in the middle of the inside of the receiving cylinder.

[0007] In a preferred embodiment, the fixing frame includes a hanging bracket, with a U-shaped support welded to the left and right sides of the hanging bracket. The hanging bracket has an I-shaped structure, and its upper surface has multiple limiting holes extending downwards to accommodate anti-clogging injection needles. The inner diameter of the limiting holes is smaller than the diameter of the tip of the anti-clogging injection needle.

[0008] In a preferred embodiment, a lead screw for driving the lifting platform and two guide rods for guiding and limiting the lifting platform are installed on the rear side of the vertical plate. The lower end of the lead screw is rotatably connected to the boss on the rear side of the vertical plate through a bearing.

[0009] In a preferred embodiment, a servo motor and a right-angle reducer are installed inside the rear side of the drive box to drive the lead screw to rotate. Three diaphragm liquid pumps are installed inside the front side of the drive box. The three diaphragm liquid pumps are connected to storage cylinders containing methanol, isopropanol, and hot water respectively via hoses. The three diaphragm liquid pumps are also connected to the upper side of the flushing tube via hoses and a three-way solenoid valve. A three-way pipe connector is provided on the upper side of the flushing tube. In actual use, the storage cylinders for methanol, isopropanol, and hot water can be set externally, as needed, as long as they can normally supply methanol, isopropanol, and hot water. The three-way solenoid valve and the three-way pipe connector can both be commercially available products, as long as they can respectively deliver methanol, isopropanol, and hot water. The lower end of the flushing tube is provided with a connector for sealing connection with the top of the anti-clogging injection needle and for delivering flushing fluid into the anti-clogging injection needle.

[0010] In a preferred embodiment, the rear side of the lifting platform is connected to the lead screw via a bushing and a nut, the middle part of the lifting platform is slidably connected to the middle of the vertical plate, and a strip-shaped groove is provided in the middle of the vertical plate from top to bottom.

[0011] In a preferred embodiment, the bottom of the receiving cylinder is connected to a drain pipe and connected to an external wastewater recovery device, and the upper side of the receiving cylinder is designed to be open.

[0012] In a preferred embodiment, the second fixing frame includes a top plate with a through hole extending downward through the middle for placing an anti-clogging injection needle. A fixed half-ring is fixed on the right side of the upper surface of the top plate, and a movable half-ring is magnetically mounted on the left side of the upper surface of the top plate. Both the fixed half-ring and the movable half-ring are made of permanent magnet material, and both have a rubber film layer at their opposite ends for impact protection. The fixed half-ring and the movable half-ring are connected by magnetic attraction, allowing for quick fixing and quick disassembly of the anti-clogging injection needle.

[0013] In a preferred embodiment, a cylindrical hole is formed between the fixed half-ring and the movable half-ring, and its axis is collinear with the axis of the through hole on the top plate. The axis of the through hole on the top plate is collinear with the axis of the flushing pipe. Three legs arranged in an equilateral triangle structure are welded to the lower surface of the top plate and fixedly connected to the bottom of the receiving cylinder.

[0014] After adopting the above technical solution, the beneficial effects of this utility model are: 1. By setting up an ultrasonic cleaner, which is equipped with multiple fixing brackets, the anti-clogging injection needles can be cleaned stably. Their relatively neat placement prevents excessive collisions between the anti-clogging injection needles and keeps them at a certain distance from each other, thus avoiding affecting the ultrasonic cleaning effect.

[0015] 2. The flushing assembly is designed to thoroughly clean the anti-clogging injection needle after ultrasonic cleaning by using a multi-liquid flushing method. Hot water flushing prevents the residue of other liquids, ensuring that there are no impurities inside the anti-clogging injection needle. This helps to improve the flushing effect on the anti-clogging injection needle and solves the problem that traditional backflushing and ultrasonic cleaning methods are unable to completely remove the residual substances on the inner wall of the needle, which gradually cause the injection needle to become clogged over time. Attached Figure Description

[0016] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0017] Figure 1 This is a schematic diagram of the overall structure of a liquid chromatograph anti-clogging injection needle cleaning device according to the present invention.

[0018] Figure 2 This is a schematic diagram of the ultrasonic cleaner structure of a liquid chromatograph anti-clogging injection needle cleaning device according to the present invention.

[0019] Figure 3 This is a schematic diagram showing the connection between the fixing frame and the placement frame of the anti-clogging injection needle cleaning device for liquid chromatograph according to this utility model.

[0020] Figure 4 This is a schematic diagram of the rinsing component structure of a liquid chromatograph anti-clogging injection needle cleaning device according to the present invention.

[0021] Figure 5 This is a schematic diagram of the fixing frame structure of the anti-clogging injection needle cleaning device for liquid chromatograph according to the present invention.

[0022] Figure 6 This is a schematic diagram of the fixing frame two of the anti-clogging injection needle cleaning device for liquid chromatograph according to the present invention.

[0023] In the diagram, 100-ultrasonic cleaner, 110-cleaning tank, 120-placement rack, 130-fixed frame one, 131-bracket, 132-hanging bracket, 133-limiting hole;

[0024] 200-Flushing assembly, 210-Vertical plate, 220-Lifting platform, 230-Receiving cylinder, 240-Fixed frame II, 241-Top plate, 242-Modible half ring, 243-Fixed half ring, 244-Outrigger, 250-Flushing pipe, 260-Drive box. Detailed Implementation

[0025] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0026] As the first embodiment of this utility model:

[0027] Please see Figures 1 to 6 A cleaning device for anti-clogging injection needles for liquid chromatographs includes: an ultrasonic cleaner 100, a rinsing assembly 200 for rinsing the anti-clogging injection needles installed on the rear side of the ultrasonic cleaner 100, a cleaning pool 110 provided inside the upper side of the ultrasonic cleaner 100 and a placement rack 120 movably placed therein, and a plurality of fixing racks 130 for hanging anti-clogging injection needles movably placed on the upper side of the placement rack 120.

[0028] The rinsing assembly 200 includes a vertical plate 210, a drive box 260 fixed to the top of the vertical plate 210, a rinsing tube 250 for conveying rinsing fluid installed on the lower front side of the drive box 260, a lifting platform 220 movably installed on the lower front side of the vertical plate 210, a receiving tube 230 movably installed on the upper side of the lifting platform 220, and a fixing bracket 240 for fixing the anti-clogging injection needle fixed in the middle inside the receiving tube 230.

[0029] The fixed frame 130 includes a bracket 132. A U-shaped support 131 is welded to the left and right sides of the bracket 132. The bracket 132 has an I-shaped structure, and its upper surface extends downward to form multiple limiting holes 133 for placing anti-clogging injection needles. The inner diameter of the limiting holes 133 is smaller than the diameter of the tip of the anti-clogging injection needle.

[0030] Specifically, by setting up the ultrasonic cleaner 100, in actual use, multiple anti-clogging injection needles to be cleaned are placed one by one in the limiting holes 133 on the fixing bracket 130. Then, the multiple fixing brackets 130 are placed on the placement rack 120 in the cleaning tank 110 of the ultrasonic cleaner 100. The ultrasonic cleaner 100 is started to clean the anti-clogging injection needles for 15 to 25 minutes. After that, the anti-clogging injection needles can be taken out one by one for the next rinsing work. The ultrasonic cleaner 100, together with the multiple fixing brackets 130, can stably clean the anti-clogging injection needles. Their relatively neat placement prevents excessive collision between the anti-clogging injection needles and maintains a certain distance between them, which can avoid affecting the effect of ultrasonic cleaning.

[0031] As a second embodiment of this utility model:

[0032] Please see Figures 1 to 6 The rear side of the vertical plate 210 is equipped with a lead screw for driving the lifting platform 220 and two guide rods for guiding and limiting the lifting platform 220. The lower end of the lead screw is rotatably connected to the boss on the rear side of the vertical plate 210 through a bearing.

[0033] The rear of the drive box 260 houses a servo motor and a right-angle reducer to drive the lead screw. The front of the drive box 260 houses three diaphragm pumps, which are connected via hoses to storage containers containing methanol, isopropanol, and hot water, respectively. These pumps are also connected to the upper side of the flushing pipe 250 via hoses and a three-way solenoid valve. A three-way connector is located on the upper side of the flushing pipe 250. In actual use, the storage containers for methanol, isopropanol, and hot water can be externally located, depending on requirements, as long as they can supply methanol, isopropanol, and hot water normally. The three-way solenoid valve and connector can be readily available products on the market, ensuring the separate delivery of methanol, isopropanol, and hot water. The lower end of the flushing pipe 250 has a connector for sealing the top of the anti-clogging injection needle and delivering flushing fluid into the needle.

[0034] The rear side of the lifting platform 220 is connected to the lead screw via a bushing and a screw nut. The middle part of the lifting platform 220 is slidably connected to the middle of the vertical plate 210, and a strip-shaped groove is provided in the middle of the vertical plate 210 from top to bottom.

[0035] The bottom of the receiving cylinder 230 is connected to a sewage pipe and is connected to an external sewage recovery device. The upper side of the receiving cylinder 230 is designed to be open.

[0036] The second mounting bracket 240 includes a top plate 241. A through hole is formed in the middle of the top plate 241 to accommodate the anti-clogging injection needle. A fixed half-ring 243 is fixed on the right side of the upper surface of the top plate 241, and a movable half-ring 242 is magnetically mounted on the left side of the upper surface of the top plate 241. Both the fixed half-ring 243 and the movable half-ring 242 are made of permanent magnet material, and both of their opposite ends are provided with a rubber film layer for anti-collision. The fixed half-ring 243 and the movable half-ring 242 are connected by magnetic attraction, which allows for quick fixing and quick disassembly of the anti-clogging injection needle.

[0037] A cylindrical hole is formed in the middle of the fixed half ring 243 and the movable half ring 242. Its axis is collinear with the axis of the through hole on the top plate 241. The axis of the through hole on the top plate 241 is collinear with the axis of the flushing pipe 250. Three legs 244 distributed in an equilateral triangle structure are welded to the lower surface of the top plate 241 and fixedly connected to the bottom of the receiving cylinder 230.

[0038] Based on the first embodiment described above, in actual use, the ultrasonically cleaned anti-clogging injection needle is placed on the second fixing frame 240. Then, the upper part of the anti-clogging injection needle is fixed to the second fixing frame 240 using the movable half-ring 242 in conjunction with the fixed half-ring 243 (the diameter of the hole between the fixed half-ring 243 and the movable half-ring 242 matches the diameter of the upper part of the anti-clogging injection needle, allowing for quick fixation). Then, the servo motor drive screw at the rear of the drive box 260 is activated to raise the lifting platform 220 until the top of the anti-clogging injection needle abuts against the lower end of the flushing tube 250. A manual sealing connection is then made. Subsequently, the diaphragm pump connected to the storage tanks of methanol, isopropanol, and hot water is started sequentially. First, methanol is delivered to flush the anti-clogging injection needle. Then, the methanol delivery is stopped, and isopropanol is delivered next. The anti-clogging injection needle is flushed with methanol, then the flow of isopropanol is stopped, and finally hot water is used for flushing. After flushing (the flushing time of methanol, isopropanol and hot water can be set according to actual needs), the connection between the flushing tube 250 and the anti-clogging injection needle can be disconnected, the lifting platform 220 is lowered, and the anti-clogging injection needle can be removed. This operation can be repeated to continuously flush the anti-clogging injection needle. The flushing component 200 can thoroughly clean the anti-clogging injection needle after ultrasonic cleaning by using multi-liquid flushing. After hot water flushing, other liquid residues can be avoided, so that there are no impurities left inside the anti-clogging injection needle, which helps to improve the flushing effect of the anti-clogging injection needle. This solves the problem that traditional backflushing and ultrasonic cleaning methods are difficult to completely remove the residual substances on the inner wall of the needle, which gradually cause the injection needle to become blocked over time.

[0039] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A clogging-preventing sample injection needle cleaning device for a liquid chromatograph, comprising: An ultrasonic cleaner (100) is characterized in that a rinsing assembly (200) for rinsing anti-clogging injection needles is installed on the rear side of the ultrasonic cleaner (100), a cleaning tank (110) is provided inside the upper side of the ultrasonic cleaner (100) and a placement rack (120) is movably placed therein, and a plurality of fixing racks (130) for hanging anti-clogging injection needles are movably placed on the upper side of the placement rack (120). The rinsing assembly (200) includes a vertical plate (210), a drive box (260) is fixed to the top of the vertical plate (210), a rinsing tube (250) for conveying rinsing fluid is installed on the lower front side of the drive box (260), a lifting platform (220) is movably installed on the lower front side of the vertical plate (210), a receiving tube (230) is movably installed on the upper side of the lifting platform (220), and a fixing bracket (240) for fixing the anti-clogging injection needle is fixed in the middle inside the receiving tube (230).

2. The anti-plugging sample injection needle cleaning device for a liquid chromatograph according to claim 1, characterized in that: The fixing frame (130) includes a bracket (132). A U-shaped support (131) is welded to the left and right sides of the bracket (132). The bracket (132) has an I-shaped structure and multiple limiting holes (133) are formed through its upper surface to place anti-clogging injection needles. The inner diameter of the limiting holes (133) is smaller than the diameter of the tip of the anti-clogging injection needle.

3. The anti-plugging sample injection needle cleaning device for liquid chromatograph of claim 2, wherein: The rear side of the vertical plate (210) is equipped with a lead screw for driving the lifting platform (220) and two guide rods for guiding and limiting the lifting platform (220). The lower end of the lead screw is rotatably connected to the boss on the rear side of the vertical plate (210) through a bearing.

4. The anti-clogging injection needle cleaning device for liquid chromatograph as described in claim 1, characterized in that: The drive box (260) is equipped with a servo motor and a right-angle reducer for driving the lead screw to rotate. The drive box (260) is equipped with three diaphragm liquid pumps. The three diaphragm liquid pumps are connected to storage cylinders containing methanol, isopropanol and hot water respectively through hoses. The three diaphragm liquid pumps are connected to the upper side of the flushing pipe (250) through hoses and a three-way solenoid valve. A three-way pipe joint is provided on the upper side of the flushing pipe (250).

5. The anti-clogging injection needle cleaning device for liquid chromatograph as described in claim 1, characterized in that: The rear side of the lifting platform (220) is connected to the lead screw via a bushing and a screw nut. The middle part of the lifting platform (220) is slidably connected to the middle of the vertical plate (210), and a strip-shaped groove is provided in the middle of the vertical plate (210) from top to bottom.

6. The anti-clogging injection needle cleaning device for liquid chromatograph as described in claim 1, characterized in that: The bottom of the receiving cylinder (230) is connected to a sewage pipe and connected to an external sewage recovery device. The upper side of the receiving cylinder (230) is designed to be open.

7. The anti-clogging injection needle cleaning device for liquid chromatograph as described in claim 6, characterized in that: The second fixing frame (240) includes a top plate (241), with a through hole extending downward through the middle of the top plate (241) for placing an anti-clogging injection needle. A fixed half ring (243) is fixed on the right side of the upper surface of the top plate (241), and a movable half ring (242) is magnetically mounted on the left side of the upper surface of the top plate (241). Both the fixed half ring (243) and the movable half ring (242) are made of permanent magnet material, and both of them have a rubber film layer at their opposite ends for anti-collision.

8. The anti-clogging injection needle cleaning device for liquid chromatograph as described in claim 7, characterized in that: A cylindrical hole is formed between the fixed half-ring (243) and the movable half-ring (242), and its axis is collinear with the axis of the through hole on the top plate (241). The axis of the through hole on the top plate (241) is collinear with the axis of the flushing pipe (250). Three legs (244) arranged in an equilateral triangle structure are welded to the lower surface of the top plate (241) and fixedly connected to the bottom of the receiving cylinder (230).

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