A rapid detection pen for papaverine compounds

By designing a rapid detection pen for papaverine compounds, utilizing an imprinted polymer pen tip and a simple flow channel structure, combined with a color developer and acidic reagent, the problems of high cost and complex pretreatment of existing equipment are solved, achieving low-cost and rapid detection of papaverine and improving regulatory efficiency.

CN224286716UActive Publication Date: 2026-05-26SHANDONG UNIV OF POLITICAL SCI & LAW

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
SHANDONG UNIV OF POLITICAL SCI & LAW
Filing Date
2025-05-30
Publication Date
2026-05-26

AI Technical Summary

Technical Problem

Existing papaverine detection equipment is costly, inconvenient, and involves complex pretreatment processes, leading to regulatory lag.

Method used

Design a rapid detection pen for papaverine compounds, employing an imprinted polymer pen tip and a simple flow channel structure, combined with a color developer and an acidic reagent, to achieve portable on-site detection.

Benefits of technology

It enables low-cost, rapid, and portable detection of papaverine, simplifies the pretreatment process, provides on-site results, reduces testing costs, and improves regulatory efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

This utility model relates to a rapid detection pen for papaverine compounds, belonging to the field of poppy detection technology. It includes a handle and a pen tip. The pen tip is threaded to the bottom of the handle. A main channel is formed in the upper middle part of the pen tip. The handle is hollow inside, and an L-shaped pipe is installed at the bottom of the handle, communicating with the main channel. A liquid reservoir is connected to the top of the L-shaped pipe, and a display ball is connected to the top of the liquid reservoir. An outflow channel is formed at the bottom of the pen tip, and several micro-channels are formed between the outflow channel and the main channel. This device is small in size, has low cost per use, and eliminates complex pretreatment processes such as extraction, purification, and concentration. It can directly detect food samples, and the entire detection process can produce results on-site in just a few minutes, enabling direct monitoring of businesses using poppies.
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Description

Technical Field

[0001] This utility model relates to the field of poppy detection technology, and in particular to a rapid detection pen for poppy alkaloid compounds. Background Technology

[0002] Papaverine is an organic compound and a major alkaloid found in poppies. With the improvement of living standards, people are paying more and more attention to food safety, and papaverine is one of the main culprits endangering food safety. Because it can cause addiction and dependence, many unscrupulous merchants have added papaverine to various foods (such as hot pot and spicy hot pot). Therefore, inspectors regularly use specialized testing equipment to identify whether food contains papaverine.

[0003] Current methods for detecting poppies mainly rely on laboratory instrument analysis, such as high performance liquid chromatography-mass spectrometry (HPLC-MS) and gas chromatography-mass spectrometry (GC-MS). While these methods have high sensitivity and accuracy, they are expensive, involve complex pretreatment processes, and are not portable. They require samples to be taken back to the laboratory for testing, resulting in regulatory delays. Utility Model Content

[0004] This invention addresses the problems in the prior art by providing a rapid detection pen for papaverine compounds, achieved through the following technical solution:

[0005] A rapid detection pen for papaverine compounds includes a handle and a pen tip. The pen tip is threaded to the bottom of the handle. A main channel is formed in the upper middle part of the pen tip. The handle is hollow inside. An L-shaped pipe is installed at the bottom of the handle and communicates with the main channel. A liquid reservoir is connected to the top of the L-shaped pipe, and a display ball is connected to the top of the liquid reservoir. An outflow channel is formed at the bottom of the pen tip, and several micro-flow channels are formed between the outflow channel and the main channel.

[0006] The present invention is further configured such that: both the liquid storage ball and the display ball are connected to a liquid inlet pipe, the liquid inlet pipe is disposed through the side wall of the handle, and a first sealing plug is detachably installed at the liquid inlet end of the liquid inlet pipe.

[0007] The present invention is further configured such that: the pen tip material is an imprint polymer, and a second sealing plug is detachably installed in the outflow channel.

[0008] The present invention is further configured such that: the transverse tube of the L-shaped pipe penetrates the side wall of the handle and extends to the outside, and a rubber suction head is threadedly connected to the outer ring of the L-shaped pipe on the outside of the handle.

[0009] The present invention is further configured such that: a first valve is installed between the L-shaped pipe and the liquid storage ball, and a second valve is installed between the liquid storage ball and the display ball, and the switches of the first valve and the second valve both extend to the outside of the handle.

[0010] The present invention is further configured such that: an observation window is provided on the side wall of the handle, and a transparent plate is installed on the observation window.

[0011] In summary, the beneficial technical effects of this utility model are as follows:

[0012] This device is small in size and has low cost per use. It eliminates the need for complex pretreatment processes such as extraction, purification, and concentration, allowing direct testing of food samples. The entire testing process takes only a few minutes to produce results on-site, enabling direct monitoring of businesses using opium poppies. The imprinted polymer pen tip is heat-resistant and acid and alkali-resistant. The handle and internal structure can be reused after cleaning, further reducing costs. Visual operation is achieved through a transparent plate and observation window. Attached Figure Description

[0013] Figure 1 This is a schematic diagram illustrating the internal structure of this utility model.

[0014] Figure 2 This is the main view used to display this utility model.

[0015] Reference numerals: 1. Handle; 2. Pen tip; 3. Main channel; 4. L-shaped pipe; 5. Liquid reservoir; 6. Display ball; 7. Outflow channel; 8. Microflow channel; 9. Inlet pipe; 10. First sealing plug; 11. Second sealing plug; 12. Rubber suction tip; 13. First valve; 14. Second valve; 15. Observation window; 16. Transparent plate. Detailed Implementation

[0016] The present invention will be further described in detail below with reference to the accompanying drawings.

[0017] Example

[0018] like Figure 1-2 As shown, this utility model discloses a rapid detection pen for papaverine compounds, including a handle 1 and a pen tip 2. The pen tip 2 is threaded to the bottom of the handle 1. A main channel 3 is opened in the upper part of the pen tip 2. The handle 1 is hollow inside. An L-shaped pipe 4 is installed at the bottom of the handle 1. The L-shaped pipe 4 is connected to the main channel 3. A liquid storage ball 5 is connected to the top of the L-shaped pipe 4. A display ball 6 is connected to the top of the liquid storage ball 5. An outflow channel 7 is opened at the bottom of the pen tip 2. Several micro-flow channels 8 are opened between the outflow channel 7 and the main channel 3.

[0019] Both the liquid storage ball 5 and the display ball 6 are connected to a liquid inlet pipe 9. The liquid inlet pipe 9 is installed through the side wall of the handle 1, and a first sealing plug 10 is detachably installed at the liquid inlet end of the liquid inlet pipe 9.

[0020] The pen tip 2 is made of imprint polymer (MIP), and a second sealing plug 11 is detachably installed in the outflow channel 7.

[0021] The horizontal tube of the L-shaped pipe 4 passes through the side wall of the handle 1 and extends to the outside. The outer ring of the L-shaped pipe 4 on the outside of the handle 1 is threaded with a rubber suction head 12.

[0022] A first valve 13 is installed between the L-shaped pipe 4 and the liquid storage ball 5, and a second valve 14 is installed between the liquid storage ball 5 and the display ball 6. The switches of the first valve 13 and the second valve 14 both extend to the outside of the handle 1.

[0023] The handle 1 has an observation window 15 on its side wall, and the observation window 15 is fitted with a transparent plate 16.

[0024] The specific implementation method of this example is as follows: Before use, inject the colorimetric reagent into the reservoir ball 5 and the acidic reagent into the display ball 6, and seal them with the first sealing plug 10. When using, remove the second sealing plug 11, pinch the rubber suction head 12, place the pen tip 2 into the hot pot liquid or other liquid to be tested, release the rubber suction head 12 to allow the hot pot liquid to be drawn into the microfluidic channel 8 through the inlet tube 9. When the hot pot liquid entering the microfluidic channel 8 contains poppy, papaverine will bind to MIP and occupy the binding site of MIP. After the liquid to be tested is discharged through the rubber suction head 12, insert the second sealing plug, open the first valve 13 to allow the colorimetric reagent to enter the microfluidic channel 8 through the main channel 3. Since papaverine has already occupied the binding site of MIP, the liquid to be tested will be drawn into the microfluidic channel 8. Since most of the binding sites of MIPs are occupied, the chromogenic agent cannot bind to most of the MIPs. After inverting the device and opening the second valve 14, the chromogenic agent enters the display ball 6 and mixes with the acidic reagent, causing a color change. The concentration of poppies can be observed based on the degree of color change. When the test liquid does not contain poppies, the test liquid will not occupy the MIP sites, and the chromogenic agent will bind to all the MIPs after entering the microfluidic channel 8. Inverting the device so that the chromogenic agent does not change color after mixing with the acidic reagent proves that it does not contain poppies. After use, disassemble the pen tip 2, open the first sealing plug 10, the first valve 13 and the second valve 14, pour out the internal liquid and clean it for the next use.

[0025] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this utility model, and not to limit it. Although this utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of this utility model.

Claims

1. A rapid detection pen for papaverine compounds, comprising a handle (1) and a pen tip (2), characterized in that: The pen tip (2) is threaded to the bottom of the handle (1). A main channel (3) is provided in the upper part of the pen tip (2). The handle (1) is hollow inside. An L-shaped pipe (4) is installed at the bottom of the handle (1). The L-shaped pipe (4) is connected to the main channel (3). A liquid storage ball (5) is connected to the top of the L-shaped pipe (4). A display ball (6) is connected to the top of the liquid storage ball (5). An outflow channel (7) is provided at the bottom of the pen tip (2). Several micro-flow channels (8) are provided between the outflow channel (7) and the main channel (3).

2. The rapid detection pen for papaverine compounds according to claim 1, characterized in that: Both the liquid storage ball (5) and the display ball (6) are connected to a liquid inlet pipe (9). The liquid inlet pipe (9) passes through the side wall of the handle (1). The liquid inlet end of the liquid inlet pipe (9) is detachably fitted with a first sealing plug (10).

3. The rapid detection pen for papaverine compounds according to claim 1, characterized in that: The pen tip (2) is made of imprint polymer, and a second sealing plug (11) is detachably installed in the outflow channel (7).

4. The rapid detection pen for papaverine compounds according to claim 1, characterized in that: The transverse tube of the L-shaped pipe (4) passes through the side wall of the handle (1) and extends to the outside. The outer ring of the L-shaped pipe (4) on the outside of the handle (1) is threaded with a rubber suction head (12).

5. The rapid detection pen for papaverine compounds according to claim 1, characterized in that: A first valve (13) is installed between the L-shaped pipe (4) and the liquid storage ball (5), and a second valve (14) is installed between the liquid storage ball (5) and the display ball (6). The switches of the first valve (13) and the second valve (14) both extend to the outside of the handle (1).

6. The rapid detection pen for papaverine compounds according to claim 1, characterized in that: The handle (1) has an observation window (15) on its side wall, and the observation window (15) is fitted with a transparent plate (16).