A reaction vessel for the production of pharmaceutical intermediates

Abstract

This utility model relates to the field of reaction vessels and discloses a reaction vessel for the production of pharmaceutical intermediates. The vessel includes a tank body with multiple support legs installed at the bottom. A partition is installed inside the tank, with guide holes on the partition. A drive motor is installed at the top of the tank body, and the output shaft of the drive motor extends into the tank body and is equipped with a stirring mechanism. A rotating shaft is rotatably mounted on the partition, and multiple side stirring rods are fixedly mounted on the rotating shaft. A connecting shaft is rotatably mounted on the partition, and a second side stirring rod is fixedly mounted on the connecting shaft. A temperature sensor is installed on the inner wall of the tank body. The stirring mechanism includes a drive shaft and a main stirring rod, with the drive shaft fixedly mounted on the output shaft of the drive motor. This utility model has the following advantages and effects: By using the main stirring rod, side stirring rods (first and second), and other stirring rods at different speeds, the materials are thoroughly mixed. Combined with precise temperature control, the reaction effect and product quality are improved.

Description

Technical Field

[0001] This utility model relates to the field of reaction vessel technology, and in particular to a reaction vessel for the production of pharmaceutical intermediates. Background Technology

[0002] In the production of pharmaceutical intermediates, reaction vessels are indispensable key equipment, mainly used to realize the chemical reactions required for the production of pharmaceutical intermediates. The reactions of pharmaceutical intermediates have extremely high requirements for the uniformity of material mixing and the precise control of reaction temperature, as these factors directly affect the quality and yield of pharmaceutical intermediates.

[0003] However, existing reaction vessels for pharmaceutical intermediate production have some shortcomings in practical use. Some reaction vessels have a relatively simple stirring structure, typically relying solely on a single stirring shaft to drive the impeller for stirring. This can easily lead to uneven mixing of materials in different areas of the vessel, especially when the vessel volume is large, causing material stratification and affecting the completeness and stability of the reaction.

[0004] Meanwhile, the temperature control of some reaction vessels is not precise enough, and the temperature during the reaction process cannot be monitored and adjusted in real time. Temperature fluctuations may affect the synthesis quality of pharmaceutical intermediates. Therefore, we propose a reaction vessel for the production of pharmaceutical intermediates to solve the above problems. Utility Model Content

[0005] The purpose of this invention is to provide a reaction vessel for the production of pharmaceutical intermediates. By using a main stirring rod, a first side stirring rod, and a second side stirring rod at different speeds, the materials can be fully mixed. Combined with precise temperature control, the reaction effect and product quality are improved.

[0006] The above-mentioned technical objective of this utility model is achieved through the following technical solution: a reaction vessel for the production of pharmaceutical intermediates, comprising a vessel body, multiple support legs installed at the bottom of the vessel body, a partition plate installed inside the vessel body, guide holes provided on the partition plate, a drive motor installed at the top of the vessel body, the output shaft of the drive motor extending into the vessel body and provided with a stirring mechanism, a rotating shaft rotatably mounted on the partition plate, multiple side stirring rods fixedly mounted on the rotating shaft, a connecting shaft rotatably mounted on the partition plate, and a side stirring rod fixedly mounted on the connecting shaft, and a temperature sensor installed on the inner wall of the vessel body.

[0007] By adopting the above technical solution, the materials are fully mixed by using the main stirring rod, side stirring rod one, and side stirring rod two at different speeds. Combined with precise temperature control, the reaction effect and product quality are improved.

[0008] A further feature of this invention is that the stirring mechanism includes a drive shaft and main stirring rods. The drive shaft is fixedly mounted on the output shaft of the drive motor, and multiple main stirring rods are fixedly mounted on the drive shaft. The main stirring rods are located between the rotating shaft and the connecting shaft, and the distance between the rotating shaft and the drive shaft is different from the distance between the connecting shaft and the drive shaft.

[0009] By adopting the above technical solution, the mixing ranges of the main stirring rod and the first and second side stirring rods can be matched without overlapping, thereby increasing the mixing coverage while avoiding interference between components.

[0010] A further feature of this invention is that: a feed pipe is installed on the top of the tank body, and the feed pipe passes through the partition; a discharge pipe is installed on one side of the tank body; a rotating disk is fixedly installed on the drive shaft; and an annular plate one and an annular plate two are fixedly installed at the bottom of the rotating disk, with the annular plate two located inside the annular plate one.

[0011] By adopting the above technical solution, the feed pipe and discharge pipe facilitate the entry and exit of materials, and the setting of annular plate one and annular plate two provides a stable structure for the transmission of multiple stirring components, thus ensuring smooth material flow and laying the foundation for stirring transmission.

[0012] A further feature of this invention is that a driving mechanism is provided between the first annular plate and the rotating shaft, and a transmission mechanism is provided between the second annular plate and the connecting shaft. The driving mechanism includes a rack and a driven gear. The rack is fixedly installed on the inner wall of the first annular plate, and the driven gear is fixedly installed at the top of the connecting shaft, and the rack and the driven gear mesh with each other.

[0013] By adopting the above technical solution, power transmission is achieved through the meshing of rack and pinion, resulting in high and stable transmission efficiency, and ensuring that the rotating shaft can rotate synchronously and stably with the annular plate.

[0014] A further feature of this invention is that the transmission mechanism includes a rack and a driven gear. The rack is mounted on the outer side of the annular plate and the driven gear is fixedly mounted on the top of the connecting shaft, and the driven bevel gear meshes with the rack.

[0015] By adopting the above technical solution, and also by using the meshing transmission of rack and pinion, the connecting shaft can rotate with the rotation of the second annular plate, thereby ensuring the stable operation of the second side stirring rod to enhance the stirring effect.

[0016] A further feature of this invention is that: a chamber is provided on the tank body, a heating wire is installed in the chamber, a temperature sensor is installed on the inner wall of the tank body, and a controller is installed on one side of the tank body, and the heating wire and the temperature sensor are electrically connected to the controller.

[0017] By adopting the above technical solutions, a complete temperature monitoring and control system is formed, which can accurately control the reaction temperature in real time, providing a suitable and stable temperature environment for the reaction of pharmaceutical intermediates.

[0018] The beneficial effects of this utility model are:

[0019] (1) When using this pharmaceutical intermediate production reaction vessel, first add the required raw materials into the vessel through the feed pipe. Start the drive motor, the drive motor drives the drive shaft to rotate, and the drive shaft drives the main stirring rod to rotate, so as to stir the raw materials.

[0020] (2) The drive shaft drives the rotating disk to rotate, and the rotating disk drives the first and second annular plates to rotate. The first annular plate drives the rotating shaft to rotate through the meshing of the first rack and the first driven gear, so that the first side stirring rod rotates and stirs; the second annular plate drives the connecting shaft to rotate through the meshing of the second rack and the second driven gear, so that the second side stirring rod rotates and stirs.

[0021] (3) During the stirring process, the temperature sensor monitors the temperature inside the tank in real time and sends the temperature information to the controller. The controller controls the operation of the heating wire according to the temperature to ensure that the reaction takes place at a suitable temperature. After the reaction is completed, the discharge pipe is opened to discharge the generated pharmaceutical intermediate. Attached Figure Description

[0022] To more clearly illustrate the technical solutions in the embodiments of this utility model, the drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0023] Figure 1 This is a three-dimensional structural schematic diagram of a reaction vessel for the production of pharmaceutical intermediates according to this utility model;

[0024] Figure 2 This is a partial cross-sectional view of a reaction vessel for producing pharmaceutical intermediates according to this utility model.

[0025] Figure 3 This is a partial three-dimensional structural schematic diagram of a reaction vessel for the production of pharmaceutical intermediates according to this utility model;

[0026] Figure 4 This is a partial bottom-view three-dimensional structural diagram of a reaction vessel for the production of pharmaceutical intermediates according to this utility model.

[0027] In the diagram, 101 is the tank body; 102 is the support leg; 103 is the partition plate; 104 is the feed pipe; 105 is the discharge pipe; 201 is the drive motor; 202 is the drive shaft; 203 is the main stirring rod; 204 is the guide hole; 301 is the rotating shaft; 302 is the first side stirring rod; 303 is the first driven gear; 401 is the connecting shaft; 402 is the second side stirring rod; 403 is the second driven gear; 501 is the rotating disk; 502 is the first annular plate; 503 is the first rack; 601 is the second annular plate; 602 is the second rack; 701 is the chamber; 702 is the heating wire; 703 is the temperature sensor; and 704 is the controller. Detailed Implementation

[0028] The technical solution of this utility model will now be clearly and completely described with reference to specific embodiments. Obviously, the described embodiments are only a part of the embodiments of this utility model, and not all of them. All other embodiments obtained by those skilled in the art based on the embodiments of this utility model without creative effort are within the scope of protection of this utility model.

[0029] When a component is described as being "set on" another component, it can be directly on the other component or it can be in an intervening component. "Set on" indicates a mode of existence, which can be a connection, installation, fixed connection, active connection, etc. When a component is described as being "connected" to another component, it can be directly connected to the other component or it may be in an intervening component.

[0030] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0031] See Figures 1-4 This utility model provides a reaction vessel for the production of pharmaceutical intermediates, including a tank body 101. Multiple support legs 102 are installed at the bottom of the tank body 101. A partition 103 is installed inside the tank body 101, and a guide hole 204 is provided on the partition 103. A drive motor 201 is installed at the top of the tank body 101. The output shaft of the drive motor 201 extends into the tank body 101 and is equipped with a stirring mechanism. A rotating shaft 301 is rotatably mounted on the partition 103, and multiple side stirring rods 302 are fixedly mounted on the rotating shaft 301. A connecting shaft 401 is rotatably mounted on the partition 103, and a second side stirring rod 402 is fixedly mounted on the connecting shaft 401. A temperature sensor 703 is installed on the inner wall of the tank body 101.

[0032] Specifically, the stirring mechanism includes a drive shaft 202 and main stirring rods 203. The drive shaft 202 is fixedly mounted on the output shaft of the drive motor 201, and multiple main stirring rods 203 are fixedly mounted on the drive shaft 202.

[0033] Specifically, the main stirring rod 203 is located between the rotating shaft 301 and the connecting shaft 401, and the distance between the rotating shaft 301 and the drive shaft 202 is different from the distance between the connecting shaft 401 and the drive shaft 202.

[0034] Specifically, a feed pipe 104 is installed on the top of the tank 101, and the feed pipe 104 passes through the partition 103. A discharge pipe 105 is installed on one side of the tank 101.

[0035] Specifically, a rotating disk 501 is fixedly installed on the drive shaft 202, and an annular plate 502 and an annular plate 601 are fixedly installed at the bottom of the rotating disk 501. The annular plate 601 is located inside the annular plate 502.

[0036] Specifically, a driving mechanism is provided between the annular plate 502 and the rotating shaft 301, and a transmission mechanism is provided between the annular plate 601 and the connecting shaft 401.

[0037] Specifically, the drive mechanism includes a rack 503 and a driven gear 303. The rack 503 is fixedly installed on the inner wall of the annular plate 502, and the driven gear 303 is fixedly installed at the top of the connecting shaft 401, and the rack 503 meshes with the driven gear 303.

[0038] Specifically, the transmission mechanism includes a rack 602 and a driven gear 403. The rack 602 is mounted on the outer side of the annular plate 601, and the driven gear 403 is fixedly mounted on the top of the connecting shaft 401, and the driven bevel gear meshes with the rack 602.

[0039] Specifically, a chamber 701 is provided on the tank body 101, and a heating wire 702 is installed in the chamber 701.

[0040] Specifically, a temperature sensor 703 is installed on the inner wall of the tank 101, and a controller 704 is installed on one side of the tank 101. The heating wire 702 and the temperature sensor 703 are both electrically connected to the controller 704.

[0041] Working principle: When using this pharmaceutical intermediate production reaction vessel, the required raw materials are first added into the vessel body 101 through the feed pipe 104. The drive motor 201 is started, which drives the drive shaft 202 to rotate, and the drive shaft 202 drives the main stirring rod 203 to rotate, thus stirring the raw materials.

[0042] Simultaneously, the drive shaft 202 drives the rotating disk 501 to rotate, and the rotating disk 501 drives the annular plate 502 and the annular plate 601 to rotate. The annular plate 502 drives the rotating shaft 301 to rotate through the meshing of the rack 503 and the driven gear 303, causing the side stirring rod 302 to rotate and stir; the annular plate 601 drives the connecting shaft 401 to rotate through the meshing of the rack 602 and the driven gear 403, causing the side stirring rod 402 to rotate and stir.

[0043] Furthermore, the rotational speed of the main stirring rod 203 is directly determined by the drive shaft 202, while the rotational speeds of the first side stirring rod 302 and the second side stirring rod 402 differ due to their respective transmission ratios. This design of different rotational speeds can generate multiple material flows of varying intensities, creating a more complex convection and turbulence state within the tank 101. The main stirring rod 203 agitates the material in the middle at a certain rotational speed, forming the main stirring flow field; the first side stirring rod 302 and the second side stirring rod 402 agitate the side areas at different rotational speeds, breaking the stable flow state formed by a single rotational speed, allowing materials in different areas to mix, collide, and contact more fully, greatly reducing the mixing time, improving mixing efficiency, ensuring that the pharmaceutical intermediate reaction can proceed uniformly and fully, and effectively improving the reaction effect and product quality.

[0044] During the stirring process, temperature sensor 703 monitors the temperature inside tank 101 in real time and sends the temperature information to controller 704. Controller 704 controls the operation of heating wire 702 according to the temperature to ensure that the reaction takes place at a suitable temperature. After the reaction is completed, discharge pipe 105 is opened to discharge the generated pharmaceutical intermediate.

[0045] The above provides a detailed description of a reaction vessel for producing pharmaceutical intermediates according to this utility model. Specific embodiments have been used to illustrate the principles and implementation methods of this utility model. The descriptions of these embodiments are merely for the purpose of helping to understand the method and core ideas of this utility model. It should be noted that those skilled in the art can make various improvements and modifications to this utility model without departing from its principles, and these improvements and modifications also fall within the protection scope of the claims of this utility model.

Claims

1. A reaction vessel for producing pharmaceutical intermediates, characterized in that, The device includes a tank (101), with multiple support legs (102) installed at the bottom of the tank (101), a partition (103) installed inside the tank (101), a guide hole (204) provided on the partition (103), and a drive motor (201) installed at the top of the tank (101). The output shaft of the drive motor (201) extends into the tank (101) and is provided with a stirring mechanism. A rotating shaft (301) is rotatably mounted on the partition (103), and a plurality of side stirring rods (302) are fixedly mounted on the rotating shaft (301). A connecting shaft (401) is rotatably mounted on the partition (103), and a side stirring rod (402) is fixedly mounted on the connecting shaft (401). A temperature sensor (703) is installed on the inner wall of the tank (101).

2. The reaction vessel for producing pharmaceutical intermediates according to claim 1, characterized in that: The stirring mechanism includes a drive shaft (202) and main stirring rods (203). The drive shaft (202) is fixedly mounted on the output shaft of the drive motor (201), and multiple main stirring rods (203) are fixedly mounted on the drive shaft (202).

3. The reaction vessel for producing pharmaceutical intermediates according to claim 2, characterized in that: The main stirring rod (203) is located between the rotating shaft (301) and the connecting shaft (401), and the distance between the rotating shaft (301) and the drive shaft (202) is different from the distance between the connecting shaft (401) and the drive shaft (202).

4. The reaction vessel for producing pharmaceutical intermediates according to claim 1, characterized in that: The top of the tank (101) is equipped with a feed pipe (104) that passes through the partition (103), and a discharge pipe (105) is installed on one side of the tank (101).

5. A reaction vessel for producing pharmaceutical intermediates according to claim 2, characterized in that: A rotating disk (501) is fixedly installed on the drive shaft (202). An annular plate one (502) and an annular plate two (601) are fixedly installed at the bottom of the rotating disk (501). The annular plate two (601) is located inside the annular plate one (502).

6. A reaction vessel for producing pharmaceutical intermediates according to claim 5, characterized in that: A driving mechanism is provided between the first annular plate (502) and the rotating shaft (301), and a transmission mechanism is provided between the second annular plate (601) and the connecting shaft (401).

7. A reaction vessel for producing pharmaceutical intermediates according to claim 6, characterized in that: The drive mechanism includes a rack (503) and a driven gear (303). The rack (503) is fixedly installed on the inner wall of the annular plate (502). The driven gear (303) is fixedly installed at the top of the connecting shaft (401), and the rack (503) meshes with the driven gear (303).

8. A reaction vessel for producing pharmaceutical intermediates according to claim 6, characterized in that: The transmission mechanism includes a rack (602) and a driven gear (403). The rack (602) is mounted on the outer side of the annular plate (601), and the driven gear (403) is fixedly mounted on the top of the connecting shaft (401). The driven bevel gear meshes with the rack (602).

9. A reaction vessel for producing pharmaceutical intermediates according to claim 1, characterized in that: The tank (101) has a chamber (701) and a heating wire (702) is installed in the chamber (701).

10. A reaction vessel for producing pharmaceutical intermediates according to claim 1, characterized in that: A temperature sensor (703) is installed on the inner wall of the tank (101), and a controller (704) is installed on one side of the tank (101). The heating wire (702) and the temperature sensor (703) are both electrically connected to the controller (704).

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