Ultrasonic heating module for nucleic acid extraction device and nucleic acid extraction device

Abstract

This application discloses an ultrasonic heating module for a nucleic acid extraction device and the nucleic acid extraction device itself. The ultrasonic heating module includes: a mounting frame assembly with a first space and a second space arranged longitudinally adjacent to each other, the second space accommodating a reagent tube that moves laterally; a mounting plate arranged vertically and movably disposed in the first space; an ultrasonic unit disposed on the mounting plate and used to output ultrasonic waves; a heating unit disposed on the mounting plate and located on one side of the ultrasonic unit, the heating unit being used to perform a heating function; and a driving component drivingly connected to the mounting plate. This ultrasonic heating module for a nucleic acid extraction device has the advantages of simple structure, low energy consumption, and small space occupation.

Description

Technical Field

[0001] This application belongs to the field of nucleic acid extraction technology, specifically relating to an ultrasonic heating module and a nucleic acid extraction device for use in a nucleic acid extraction apparatus. Background Technology

[0002] Nucleic acid extraction devices (such as nucleic acid extractors) belong to the field of molecular detection equipment and are widely used in various fields such as disease control centers, clinical disease diagnosis, blood transfusion safety, forensic identification, environmental microbiology testing, food safety testing, animal husbandry, and molecular biology research. Before nucleic acid extraction, nucleic acid extraction devices lyse the reagents in the reagent tubes. To reduce adverse effects on intracellular substances in the reagents, an ultrasonic unit is typically used for ultrasonic lysis, and a heating module is used for heating. However, existing nucleic acid extraction devices require multiple drivers to separately power the ultrasonic unit and the heating module, resulting in complex structures, high energy consumption, and large overall space requirements, making them inconvenient for transportation or direct placement in biosafety cabinets. Utility Model Content

[0003] The purpose of this application is to provide an ultrasonic heating module for a nucleic acid extraction device and a nucleic acid extraction device. The ultrasonic heating module for the nucleic acid extraction device has the advantages of simple structure, low energy consumption and small space occupation.

[0004] To achieve the above objectives, the first aspect of this application provides an ultrasonic heating module for a nucleic acid extraction apparatus, the ultrasonic heating module comprising:

[0005] The mounting frame assembly has a first space and a second space that are longitudinally adjacent to each other, the second space being used to accommodate reagent tubes that move laterally.

[0006] Mounting plates are vertically distributed and can be moved longitudinally within the first space;

[0007] An ultrasonic unit, mounted on a mounting plate, is used to output ultrasonic waves;

[0008] The heating unit is mounted on the mounting plate and located on one side of the ultrasonic unit. The heating unit is used to realize the heating function.

[0009] The driver component is connected to the mounting plate.

[0010] In embodiments of this application, the ultrasound unit includes:

[0011] Ultrasonic mounting components are mounted on the mounting plate;

[0012] An ultrasonic probe is mounted on an ultrasonic mounting assembly, and the end of the ultrasonic probe facing the reagent tube has a first arc-shaped wall for fitting against the outer peripheral wall of the reagent tube.

[0013] In embodiments of this application, the ultrasonic unit further includes a first elastic component disposed on the ultrasonic mounting assembly and capable of elastically pressing the ultrasonic probe against the reagent tube.

[0014] In embodiments of this application, the heating unit includes:

[0015] Heated mounting components are mounted on the mounting plate;

[0016] A heating element is mounted on a heating mounting assembly, and the end of the heating element facing the reagent tube has a second arc-shaped wall for fitting against the outer peripheral wall of the reagent tube.

[0017] In embodiments of this application, the heating assembly includes:

[0018] The first heat insulation element is installed on the heating mounting assembly;

[0019] The second heat insulation element is disposed on the heating mounting assembly and located on the side of the first heat insulation element near the reagent tube, and a mounting cavity is formed on the second heat insulation element;

[0020] A heating element is disposed between the first heat insulation element and the second heat insulation element;

[0021] A heat-conducting component is embedded in the mounting cavity and abuts against the heating component, and a second arc-shaped wall is formed on the heat-conducting component.

[0022] In embodiments of this application, the heating unit further includes a temperature sensor disposed on the heating element and used to detect the temperature of the heating element.

[0023] In embodiments of this application, the heating unit further includes a second elastic component disposed on the heating mounting assembly and capable of elastically pressing the heat-conducting element against the reagent tube.

[0024] In embodiments of this application, the ultrasonic heating module further includes a guide assembly disposed on the mounting bracket assembly and used for moving and guiding the mounting plate.

[0025] In embodiments of this application, the ultrasonic heating module further includes a limiting component disposed on the mounting bracket assembly and used to limit the movement distance of the mounting plate.

[0026] A second aspect of this application provides a nucleic acid extraction device, which includes the ultrasonic heating module described above for a nucleic acid extraction device.

[0027] As shown in the above technical solution, the ultrasonic heating module includes a mounting frame assembly, a mounting plate, an ultrasonic unit, a heating unit, and a driving component. The mounting frame assembly forms a first space and a second space that are longitudinally adjacent to each other. The second space is used to accommodate reagent tubes that move laterally. The mounting plate is vertically distributed and longitudinally movable within the first space. The ultrasonic unit is mounted on the mounting plate and outputs ultrasonic waves. The heating unit is mounted on the mounting plate and located on one side of the ultrasonic unit, and performs the heating function. The driving component is driven to connect with the mounting plate. This ultrasonic heating module has a simple structure, and only one driving component is needed to drive the movement of the ultrasonic unit and the heating unit. This type of ultrasonic heating module has fewer driving components, reducing energy consumption and shrinking the overall size of the ultrasonic heating module.

[0028] Other features and advantages of the embodiments of this application will be described in detail in the following detailed description section. Attached Figure Description

[0029] The accompanying drawings are provided to further illustrate the embodiments of this application and form part of the specification. They are used together with the following detailed description to explain the embodiments of this application, but do not constitute a limitation on the embodiments of this application. For those skilled in the art, other drawings can be obtained based on the structures shown in these drawings without any inventive effort. In the drawings:

[0030] Figure 1 This is a first-view structural diagram of the ultrasonic heating module in an embodiment of this application;

[0031] Figure 2 This is a second-view structural diagram of the ultrasonic heating module in an embodiment of this application;

[0032] Figure 3 This is a third-view structural diagram of the ultrasonic heating module in an embodiment of this application;

[0033] Figure 4 This is a fourth-view structural diagram of the ultrasonic heating module in the embodiments of this application;

[0034] Figure 5 This is a schematic diagram of the nucleic acid extraction device in the embodiments of this application.

[0035] Explanation of reference numerals in the attached figures

[0036] 1-Mounting frame assembly; 101-First space; 102-Second space; 103-Support column; 104-Support plate; 2-Reagent tube; 3-Mounting plate; 301-First hollow part; 302-Second hollow part; 4-Ultrasonic unit; 401-Ultrasonic mounting assembly; 402-Ultrasonic probe; 4021-First arc-shaped wall; 403-First connecting rod; 5-Heating unit; 501-Heating mounting assembly; 5011-Second connecting rod; 502-Heating... Components; 5021-Second arc-shaped wall; 5022-First heat insulation component; 5023-Second heat insulation component; 5024-Heating component; 5025-Heat conducting component; 6-Drive component; 601-Screw section; 602-Motor section; 7-Control mounting plate; 8-Ultrasonic control board; 9-Main control board; 10-Guide assembly; 1001-Guide rail; 1002-Slider; 11-Limiting assembly; 1101-Detection section; 1102-Baffle section; 12-Drive mounting component. Detailed Implementation

[0037] The specific embodiments of this application will be described in detail below with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are for illustration and explanation only and are not intended to limit this application.

[0038] Embodiments of this application provide an ultrasonic heating module for a nucleic acid extraction device, such as... Figures 1-4 As shown, the ultrasonic heating module includes:

[0039] Mounting frame assembly 1, on which a first space 101 and a second space 102 are formed adjacently along the longitudinal direction, the second space 102 being used to accommodate a reagent tube 2 that moves laterally.

[0040] Mounting plate 3 is vertically distributed and longitudinally movable in the first space 101;

[0041] Ultrasonic unit 4 is mounted on mounting plate 3 and is used to output ultrasonic waves;

[0042] Heating unit 5 is mounted on mounting plate 3 and located on one side of ultrasonic unit 4. Heating unit 5 is used to realize heating function.

[0043] The driver component 6 is connected to the mounting plate 3.

[0044] Specifically, the ultrasonic heating module in this embodiment is suitable for nucleic acid extraction devices (such as...). Figure 5As shown, the nucleic acid extraction device also includes multiple reagent tubes 2 for containing reagents. The mounting frame assembly 1 includes multiple support columns 103 and a support plate 104 arranged horizontally. The multiple support columns 103 are located below the support plate 104 and distributed at the four corners of the support plate 104. The first space 101 and the second space 102 are both located below the support plate 104. The nucleic acid extraction device also includes a lateral movement assembly arranged laterally in the second space 102. The multiple reagent tubes 2 are arranged on the lateral movement assembly. The above arrangement allows each reagent tube 2 to move laterally in the second space 102. The multiple reagent tubes 2 are loaded with different types of solutions (such as a mixture of lysis buffer and sample, buffer solution, elution buffer, etc.). Before the mounting plate 3 moves longitudinally, the lateral position of each reagent tube 2 is adjusted by the lateral movement assembly so that the reagent tube 2 loaded with the sample is aligned with the ultrasonic unit 4, and / or the reagent tube 2 corresponding to the reagent that needs to be heated is aligned with the heating unit 5. Then, under the driving action of the driving component 6, the mounting plate 3 moves longitudinally in the first space 101, thereby moving the ultrasonic unit 4 and the heating unit 5 together longitudinally to approach the reagent tube 2. After the mounting plate 3 is in place (at this time, the ultrasonic unit 4 is in contact with the reagent tube 2 containing the sample, and / or the heating unit 5 is in contact with the reagent tube 2 corresponding to the reagent that needs to be heated), the ultrasonic unit 4 turns on the ultrasonic function and outputs ultrasonic waves to the reagent tube 2. The reagent tube 2 then transfers the energy of the ultrasonic waves to the sample in the reagent tube 2. The high-frequency sound wave energy of the ultrasonic waves can break the cells so that the substances inside the cells (such as nucleic acids) flow out. After the heating unit 5 turns on the heating function, it can heat the reagents (such as the mixture of lysis buffer and sample) in the reagent tube 2, which helps the cells in the sample to release nucleic acids more quickly, laying the foundation for subsequent nucleic acid extraction. In this embodiment, the ultrasonic heating module has a simple structure, and only one driving component 6 is needed to drive the movement of the ultrasonic unit 4 and the heating unit 5. Compared with the prior art, the ultrasonic heating module with this structure has a reduced number of driving components 6, a reduced power consumption of a single driving component, a reduced standby power consumption of a single driving component, and a smaller overall size of the ultrasonic heating module.

[0045] Furthermore, the driving component 6 in this embodiment can be selected as a lead screw motor, a linear motor, a telescopic cylinder, or a synchronous belt assembly. In this embodiment, the driving component 6 is preferably a lead screw motor, which includes a lead screw portion 601 and a motor portion 602. The ultrasonic heating module also includes a driving mounting component 12 at the bottom of the support plate 104. The lead screw portion 601 is disposed on the driving mounting component 12 and distributed longitudinally. The motor portion 602 is movably disposed on the lead screw portion 601 and connected to the mounting plate 3. When the motor portion 602 moves along the lead screw portion 601, it can move synchronously with the mounting plate 3, thereby realizing the longitudinal movement of the ultrasonic unit 4 and the heating unit 5. Furthermore, the mounting plate 3 is provided with a first hollow portion 301 for the lead screw portion 601 to pass through longitudinally, so as to avoid motion interference between the mounting plate 3 and the lead screw motor.

[0046] Furthermore, the ultrasonic heating module in this embodiment also includes a control mounting plate 7 and a control module that is communicatively connected to the ultrasonic unit 4, the heating unit 5, and the driving component 6. The control mounting plate 7 is vertically arranged above the support plate 104. The control module includes an ultrasonic control board 8 and a main control board 9 disposed on the control mounting plate 7. The ultrasonic control board 8 is communicatively connected to the ultrasonic unit 4 and is used to control the ultrasonic unit 4. The main control board 9 is communicatively connected to the ultrasonic control board 8, the heating unit 5, and the driving component 6 and is used to control the heating unit 5 and the driving component 6 and to interact with the ultrasonic control board 8.

[0047] In one embodiment of this application, the ultrasound unit 4 includes:

[0048] Ultrasonic mounting assembly 401 is mounted on mounting plate 3;

[0049] An ultrasonic probe 402 is mounted on an ultrasonic mounting assembly 401. The end of the ultrasonic probe 402 facing the reagent tube 2 has a first arc-shaped wall 4021 for fitting against the outer peripheral wall of the reagent tube 2.

[0050] Specifically, the ultrasonic mounting assembly 401 includes multiple first connecting rods 403, and the ultrasonic unit 4 also includes an ultrasonic mounting plate 3 distributed vertically. The multiple first connecting rods 403 are longitudinally arranged on the mounting plate 3 and are rectangularly distributed. The ultrasonic mounting plate 3 is mounted on the multiple first connecting rods 403 (the multiple first connecting rods 403 pass through the four corners of the ultrasonic mounting plate 3 and connect to it). The ultrasonic probe 402 is mounted on the ultrasonic mounting plate 3 (i.e., in this embodiment, the ultrasonic probe 402 is mounted on the ultrasonic mounting assembly 401 via the ultrasonic mounting plate 3) and is communicatively connected to the ultrasonic control board 8. In this embodiment, the ultrasonic probe 402 is longitudinally distributed and can be optionally a piezoelectric ceramic transducer. The mounting plate 3 has a second perforated portion 302 for some of the ultrasonic probe 402 to pass through. Furthermore, since the ultrasound probe 402 is attached to the reagent tube 2 through the first arc-shaped wall 4021, the contact area between the two is relatively large (compared to the point contact between the ultrasound probe 402 and the reagent tube 2). Therefore, the ultrasound probe 402 can directly transmit ultrasonic energy to the reagent tube 2 through the first arc-shaped wall 4021. The position where the reagent tube 2 contacts the first arc-shaped wall 4021 directly and centrally receives the ultrasonic energy. That is, the ultrasonic energy is focused at the position in the reagent tube 2 corresponding to the first arc-shaped wall 4021 and transmitted to the reagent more efficiently, which improves the intensity of the ultrasonic energy received by the reagent and thus improves the efficiency of cell ultrasonic lysis in the reagent.

[0051] In one embodiment of this application, the ultrasonic unit 4 further includes a first elastic component disposed on the ultrasonic mounting assembly 401 and capable of elastically pressing the ultrasonic probe 402 against the reagent tube 2.

[0052] Specifically, the ultrasonic mounting plate 3 is movably mounted on a plurality of first connecting rods 403 (such as hexagonal screws). The first elastic component includes a plurality of first springs (not shown in the figure). The plurality of first springs correspond one-to-one with the plurality of first connecting rods 403. The first springs are sleeved on the first connecting rods 403, and one end of the first spring abuts against the ultrasonic mounting plate 3, and the other end of the first spring abuts against the mounting plate 3. The first elastic component not only prevents the ultrasonic probe 402 from impacting the reagent tube 2, thus acting as a shock absorber for the ultrasonic probe 402, but also ensures that the ultrasonic probe 402 remains elastically pressed against the reagent tube 2 even when there are errors in the installation, manufacturing, or operation of the driving component 6 and / or the ultrasonic unit 4. This ensures that the ultrasonic probe 402 can effectively perform its ultrasonic function. For example, if the driving component 6 drives the mounting plate 3 to move beyond a preset distance (when there are no errors in the installation, manufacturing, or operation of the driving component 6 and / or the ultrasonic unit 4, the first arc-shaped wall 4021 will be in close contact with the outer peripheral wall of the reagent tube 2), the elastic contraction of the first elastic component will prevent the ultrasonic probe 402 from changing the position of the reagent tube 2 and will also ensure that the first arc-shaped wall 4021 is in close contact with the outer peripheral wall of the reagent tube 2, thus expanding the allowable range of installation, manufacturing, and operation errors of the driving component 6 and / or the ultrasonic unit 4.

[0053] In one embodiment of this application, the heating unit 5 includes:

[0054] Heating mounting assembly 501 is mounted on mounting plate 3;

[0055] Heating component 502 is disposed on heating mounting component 501. The end of heating component 502 facing reagent tube 2 has a second arc-shaped wall 5021 for adhering to the outer peripheral wall of reagent tube 2.

[0056] Specifically, the heating mounting assembly 501 includes multiple second connecting rods 5011 arranged parallel to each other on a vertical plane. The second connecting rods 5011 are inserted into the mounting plate 3, and the upper and lower ends of the heating assembly 502 are respectively connected to the multiple second connecting rods 5011. After the mounting plate 3 is moved into place, the heating assembly 502 transfers heat to the reagent tube 2 through the second arc-shaped wall 5021. Since the heating assembly 502 is in contact with the reagent tube 2 through the second arc-shaped wall 5021, the contact area between the two is large, which helps to ensure the uniformity of heating of the reagent tube 2. That is, the setting of the second arc-shaped wall 5021 can improve the uniform heating effect of the reagent.

[0057] In one embodiment of this application, the heating assembly 502 includes:

[0058] The first heat insulation element 5022 is disposed on the heating mounting assembly 501;

[0059] The second heat insulation element 5023 is disposed on the heating mounting assembly 501 and located on the side of the first heat insulation element 5022 near the reagent tube 2, and a mounting cavity is formed on the second heat insulation element 5023;

[0060] The heating element 5024 is disposed between the first heat insulation element 5022 and the second heat insulation element 5023;

[0061] The heat-conducting element 5025 is embedded in the mounting cavity and abuts against the heating element 5024, and the second arc-shaped wall 5021 is formed on the heat-conducting element 5025.

[0062] Specifically, the first heat insulation element 5022 and the second heat insulation element 5023 are both made of heat insulation material (such as polypropylene) and are both connected to multiple second connecting rods 5011. The heating element 5024 can be a PI heating film and is connected to the main control board 9. The first heat insulation element 5022 and the second heat insulation element 5023 work together to provide good heat preservation for the heating element 5024 and prevent the heat emitted by the heating element 5024 from dissipating outward. The heat conduction element 5025 is made of heat conduction material (such as aluminum alloy) so that the heat conduction element 5025 can transfer the heat emitted by the heating element 5024 to the reagent tube 2 more efficiently through the second arc-shaped wall 5021.

[0063] In one embodiment of this application, the heating unit 5 further includes a temperature sensor disposed on the heating element 5024 and used to detect the temperature of the heating element 5024.

[0064] Specifically, the temperature sensor (not shown in the figure) is connected to the main control board 9 and its temperature detection end is in contact with the heating element 5024. The temperature sensor detects the temperature of the heating element 5024 and sends the detection result to the main control board 9. If the main control board 9 determines that the temperature of the heating element 5024 has reached the preset temperature based on the above detection result, it immediately controls the heating element 5024 to stop heating, which can prevent the heating unit 5 from overheating and being damaged.

[0065] In one embodiment of this application, the heating unit 5 further includes a second elastic component disposed on the heating mounting assembly 501 and capable of elastically pressing the heat-conducting element 5025 onto the reagent tube 2.

[0066] Specifically, the second connecting rod 5011 (such as a hexagonal screw) is longitudinally movable on the mounting plate 3. The second connecting rod 5011 includes a connecting rod portion and a locking head. One end of the connecting rod portion is connected to the locking head, and the other end passes through the mounting plate 3 and connects to the first heat insulation member 5022 and the second heat insulation member 5023. The connecting rod portion is movable relative to the mounting plate 3. A second spring (not shown in the figure) is sleeved on the connecting rod portion, with one end abutting against the first heat insulation member 5022 and the other end abutting against the mounting plate 3. The second elastic component not only prevents the heat-conducting component 5025 from impacting the reagent tube 2, thus providing shock absorption and cushioning for the heat-conducting component 5025, but also ensures that the heat-conducting component 5025 remains elastically pressed against the reagent tube 2 even when there are installation, manufacturing, or operational errors in the driving component 6 and / or the heating unit 5. This ensures that the heat-conducting component 5025 effectively performs its heat-conducting function. For example, if the driving component 6 drives the mounting plate 3 to move beyond a preset distance (when there are no installation, manufacturing, or operational errors in the driving component 6 and / or the heating unit 5, the second arc-shaped wall 5021 will be in close contact with the outer peripheral wall of the reagent tube 2), the elastic contraction of the second elastic component will prevent the heat-conducting component 5025 from changing the position of the reagent tube 2, and will also ensure that the second arc-shaped wall 5021 is in close contact with the outer peripheral wall of the reagent tube 2, thus expanding the allowable range of installation, manufacturing, and operational errors of the driving component 6 and / or the heating unit 5.

[0067] In one embodiment of this application, the ultrasonic heating module further includes a guide assembly 10 disposed on the mounting bracket assembly 1 and used for moving and guiding the mounting plate 3.

[0068] Specifically, the guide assembly 10 includes a guide rail 1001 and a slider 1002. The guide rail 1001 is disposed at the bottom of the support plate 104 and distributed longitudinally. The slider 1002 is movably disposed on the guide rail 1001 and connected to the mounting plate 3. The above design further ensures the stability of the movement of the mounting plate 3, avoids the mounting plate 3 from deviating from its preset movement trajectory, and ensures that the ultrasonic unit 4 and the heating unit 5 can accurately perform ultrasonic and heating functions on the reagents in their respective reagent tubes 2.

[0069] In one embodiment of this application, the ultrasonic heating module further includes a limiting component 11 disposed on the mounting bracket assembly 1 and used to limit the movement distance of the mounting plate 3.

[0070] Specifically, the limiting component 11 can be a photoelectric sensor and includes a detection unit 1101 and a baffle unit 1102. The detection unit 1101 is located at the bottom of the support plate 104 and is communicatively connected to the main control board 9. The baffle unit 1102 is connected to the slider 1002. In this embodiment, if the detection unit 1101 can continuously detect the baffle unit 1102, it means that the mounting plate 3 has not yet moved into place. At this time, the main control board 9 controls the driving component 6 to continue to perform the driving action. If the detection unit 1101 can no longer continuously detect the baffle unit 1102, it means that the mounting plate 3 has moved into place. At this time, the main control board 9 controls the driving component 6 to stop performing the driving action to avoid the ultrasonic unit 4 and / or the heating unit 5 applying excessive pushing force to the reagent tube 2, which could cause the reagent tube 2 to be damaged or detached from the lateral moving component.

[0071] Furthermore, in this embodiment, the mounting plate 3 can be made of aluminum alloy. This material can ensure the structural strength of the mounting plate 3 while reducing its weight, which is beneficial for achieving a lightweight design of the ultrasonic heating module.

[0072] Another embodiment of this application provides a nucleic acid extraction device, which includes the ultrasonic heating module for nucleic acid extraction devices described in the above embodiments.

[0073] In the description of this application, it should be understood that the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this application, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0074] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection, an electrical connection, or a connection that allows communication between components; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise expressly limited. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0075] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., refer to specific features, structures, materials, or characteristics described in connection with that embodiment or example, which are included in at least one embodiment or example of this application. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0076] Although embodiments of this application have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting this application. Those skilled in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of this application.

Claims

1. An ultrasonic heating module for a nucleic acid extraction device, characterized in that, The ultrasonic heating module includes: Mounting rack assembly (1) having a first space (101) and a second space (102) arranged longitudinally adjacent to each other, the second space (102) being used to accommodate a reagent tube (2) that moves laterally. Mounting plate (3) is vertically distributed and longitudinally movable in the first space (101); An ultrasonic unit (4) is mounted on the mounting plate (3) and is used to output ultrasonic waves; A heating unit (5) is disposed on the mounting plate (3) and located on the lateral side of the ultrasonic unit (4). The heating unit (5) is used to realize the heating function. The driving component (6) is driven to connect with the mounting plate (3).

2. The ultrasonic heating module for a nucleic acid extraction device according to claim 1, characterized in that, The ultrasound unit (4) includes: An ultrasonic mounting assembly (401) is disposed on the mounting plate (3); An ultrasonic probe (402) is disposed on the ultrasonic mounting assembly (401), and the end of the ultrasonic probe (402) facing the reagent tube (2) has a first arc-shaped wall (4021) for fitting against the outer peripheral wall of the reagent tube (2).

3. The ultrasonic heating module for a nucleic acid extraction device according to claim 2, characterized in that, The ultrasound unit (4) further includes a first elastic component disposed on the ultrasound mounting assembly (401) and capable of elastically pressing the ultrasound probe (402) onto the reagent tube (2).

4. The ultrasonic heating module for a nucleic acid extraction device according to claim 1, characterized in that, The heating unit (5) includes: A heating mounting assembly (501) is disposed on the mounting plate (3); A heating assembly (502) is disposed on the heating mounting assembly (501), and the end of the heating assembly (502) facing the reagent tube (2) has a second arc-shaped wall (5021) for fitting against the outer peripheral wall of the reagent tube (2).

5. The ultrasonic heating module for a nucleic acid extraction device according to claim 4, characterized in that, The heating assembly (502) includes: A first heat insulation element (5022) is disposed on the heating mounting assembly (501); The second heat insulation element (5023) is disposed on the heating mounting assembly (501) and located on the side of the first heat insulation element (5022) near the reagent tube (2), and a mounting cavity is formed on the second heat insulation element (5023); A heating element (5024) is disposed between the first heat insulation element (5022) and the second heat insulation element (5023); A heat-conducting element (5025) is embedded in the mounting cavity and abuts against the heating element (5024), and the second arc-shaped wall (5021) is formed on the heat-conducting element (5025).

6. The ultrasonic heating module for a nucleic acid extraction device according to claim 5, characterized in that, The heating unit (5) further includes a temperature sensor disposed on the heating element (5024) and used to detect the temperature of the heating element (5024).

7. The ultrasonic heating module for a nucleic acid extraction device according to claim 5, characterized in that, The heating unit (5) further includes a second elastic component disposed on the heating mounting assembly (501) and capable of elastically pressing the heat-conducting element (5025) onto the reagent tube (2).

8. The ultrasonic heating module for a nucleic acid extraction device according to claim 1, characterized in that, The ultrasonic heating module also includes a guide assembly (10) disposed on the mounting bracket assembly (1) and used to move and guide the mounting plate (3).

9. The ultrasonic heating module for a nucleic acid extraction device according to any one of claims 1-8, characterized in that, The ultrasonic heating module also includes a limiting component (11) disposed on the mounting bracket assembly (1) and used to limit the movement distance of the mounting plate (3).

10. A nucleic acid extraction device, characterized in that, The nucleic acid extraction device includes an ultrasonic heating module for a nucleic acid extraction device according to any one of claims 1-9.

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