O / w-type low-viscosity emulsion composition containing adenosine phosphate

Abstract

To provide a low viscosity (less than 10000 mPa s) O / W type emulsion composition containing adenosine phosphate and / or a salt thereof and an acrylic acid-alkyl methacrylate copolymer having good emulsion stability.SOLUTION: There is provided an O / W type emulsion composition which comprises adenosine phosphate and / or a salt thereof, an acrylic acid-alkyl methacrylate copolymer, an oil and water and further comprises a water-soluble polymer selected from a swelling-type thickener, an associative thickener, polysaccharides and derivatives thereof, and a mixture thereof and / or a pH adjuster which is an organic alkali and has a viscosity of less than 10000 mPa s.SELECTED DRAWING: None

Description

[Technical field]

[0001] The present application relates to an O / W type low-viscosity emulsion composition containing adenosine phosphate and / or a salt thereof, and an acrylic acid / alkyl methacrylate copolymer. [Background technology]

[0002] Adenosine phosphate is known to have moisturizing and whitening effects, and various cosmetics containing adenosine phosphate have already been investigated (eg, Patent Document 1) and are on the market. Alkyl acrylate copolymers are known as polymeric emulsifiers suitable for the formulation of gel creams and emulsions that have a refreshing and fresh feel when used. [Prior art documents] [Patent documents]

[0003] [Patent Document 1] International Publication No. 2002 / 41853

[0004] The disclosures of all prior art documents cited in this specification are hereby incorporated by reference. Summary of the Invention [Problem to be solved by the invention]

[0005] The present inventors attempted to develop a low-viscosity (less than 10,000 mPa s) O / W type emulsion composition containing adenosine phosphate and an acrylic acid / alkyl methacrylate copolymer, but encountered the problem of being unable to obtain a composition with good emulsion stability.The objective of the present invention is to provide a low-viscosity (less than 10,000 mPa s) O / W type emulsion composition with good emulsion stability that contains adenosine phosphate and / or a salt thereof and an acrylic acid / alkyl methacrylate copolymer. [Means for solving the problem]

[0006] The present inventors have conducted extensive research to solve the above-mentioned problems and have unexpectedly found that a specific water-soluble polymer and a specific pH adjuster each improve the emulsion stability of a composition containing adenosine phosphate and / or a salt thereof and an acrylic acid / alkyl methacrylate copolymer. In addition, it has been found that the feel of the composition when used can be further improved by further adding a non-crystalline high-melting point oil having a melting point of 30°C or higher; a gelling agent for the oil-based component; and / or a silicone feel improver.

[0007] That is, the present application provides the following aspects of the invention.

[0008] [1] An O / W type emulsion composition comprising component (A), component (B), component (E), and component (F), and also comprising component (C) and / or component (D), and having a viscosity of less than 10,000 mPa s (e.g., 200 to 10,000 mPa s, 300 to 9,000 mPa s, 500 to 8,000 mPa s, 1,000 to 5,000 mPa s, 1,500 to 3,000 mPa s): Component (A): Adenosine phosphate and / or its salt; Component (B): acrylic acid-alkyl methacrylate copolymer; Component (C): a water-soluble polymer selected from a swelling type thickener, an associative type thickener, a polysaccharide and its derivatives, and a mixture thereof; Component (D): pH adjuster which is an organic alkali; Ingredient (E): Oil; Ingredient (F): Water.

[0009] [2] The composition according to [1], wherein the component (B) is an acrylic acid / alkyl methacrylate copolymer having a molecular weight of 100,000 to 5,000,000.

[0010] [3] The composition according to [1] or [2], wherein the component (B) is an acrylate / alkyl methacrylate copolymer having an alkyl group with 8 to 35 carbon atoms.

[0011] [4] The composition according to any one of [1] to [3], wherein the component (B) is an (acrylates / C10-30 alkyl acrylate) crosspolymer.

[0012] [5] Component (C) is a swelling type thickener selected from sodium polyacrylate, ammonium polyacrylate, acrylamide / sodium acrylate copolymer, vinylpyrrolidone / 2-acrylamido-2-methylpropanesulfonic acid copolymer, a mixture of polyacrylic acid amide and sodium polyacrylate, sodium acrylate / 2-acrylamido-2-methylpropanesulfonic acid copolymer, hydroxyethyl acrylate / 2-acrylamido-2-methylpropanesulfonic acid copolymer, and mixtures thereof; an associative thickener selected from polyacrylic acid associative thickeners, polyvinyl alcohol, polyvinyl thickeners, polyether associative thickeners, polyglycol associative thickeners, maleic anhydride copolymer associative thickeners, polyamide associative thickeners, polyester associative thickeners, hydrophobized cellulose ester associative thickeners, urethane associative thickeners, polycarboxylic acid associative thickeners, and mixtures thereof; Polysaccharides and derivatives thereof selected from xanthan gum, guar gum, carrageenan, tamarind gum, quince seed gum, sclerotium gum, agar, cationized xanthan gum, cationized cellulose, hydroxypropyl starch phosphate and mixtures thereof; and The composition according to any one of [1] to [4], wherein the water-soluble polymer is selected from the mixture thereof.

[0013] [6] Component (C) is a swelling type thickener selected from sodium polyacrylate, ammonium polyacrylate, acrylamide / sodium acrylate copolymer, vinylpyrrolidone / 2-acrylamido-2-methylpropanesulfonic acid copolymer, a mixture of polyacrylic acid amide and sodium polyacrylate, sodium acrylate / 2-acrylamido-2-methylpropanesulfonic acid copolymer, hydroxyethyl acrylate / 2-acrylamido-2-methylpropanesulfonic acid copolymer, and mixtures thereof; a urethane associative thickener selected from (PEG-240 / Decyltetradeceth-20 / HDI) copolymer, (PEG-150 / Stearyl alcohol / SMDI) copolymer, (PEG-150 / Decyl alcohol / SMDI) copolymer, polyurethane-59, and mixtures thereof; and The composition according to any one of [1] to [5], wherein the water-soluble polymer is selected from the mixture thereof.

[0014] [7] The composition according to any one of [1] to [6], wherein the component (C) is selected from sodium polyacrylate, (PEG-240 / decyltetradeceth-20 / HDI) copolymer, and a mixture thereof.

[0015] [8] The composition according to any one of [1] to [7], wherein the component (C) is sodium polyacrylate.

[0016] [9] The composition according to any one of [1] to [8], wherein the component (D) is a pH adjuster which is an organic alkali selected from the group consisting of tromethamine, aminomethylpropanediol, aminomethylpropanol, arginine, and mixtures thereof.

[0017]

[10] The composition according to any one of [1] to [9], wherein component (D) is tromethamine, arginine, or a mixture thereof.

[0018]

[11] The composition according to any one of [1] to

[10] , wherein the component (D) is tromethamine.

[0019]

[12] The composition according to any one of [1] to

[11] , which contains a component (C) and has a component (C) / component (A) (weight ratio) of 0.01 to 30 (preferably 0.01 to 20, more preferably 0.02 to 10, more preferably 0.03 to 5, still more preferably 0.04 to 0.8, or 0.1 to 0.5).

[0020]

[13] The composition according to any one of [1] to

[12] , which contains a component (C) and has a weight ratio of component (C) / (component (A)+component (B)) of 0.005 to 20 (preferably 0.01 to 10, more preferably 0.02 to 5, even more preferably 0.01 to 1.5, still more preferably 0.04 to 0.7, or 0.1 to 0.3).

[0021]

[14] The composition according to any one of [1] to

[13] , which has a pH of 5.5 to 7.5 (preferably pH 6 to 7, for example pH 6.5 to 7).

[0022]

[15] The composition according to any one of [1] to

[14] , which contains a component (D) and has a pH of 5.5 to 7.5 (preferably pH 6 to 7, for example pH 6.5 to 7).

[0023]

[16] Does not contain an inorganic alkaline pH adjuster, or The composition according to any one of [1] to

[15] , which contains an inorganic alkaline pH adjuster and has a weight ratio of inorganic alkaline pH adjuster / component (D) of 0.1 or less (preferably 0.01 or less).

[0024]

[17] The composition according to any one of [1] to

[16] , wherein the weight ratio of component (C) / component (B) is 0.05 to 60 (preferably 0.1 to 30, more preferably 0.1 to 20, even more preferably 0.1 to 10, still more preferably 0.1 to 5, still more preferably 0.5 to 4, or 0.3 to 1).

[0025]

[18] The composition according to any one of [1] to

[17] , containing 0.001 to 10 wt% of component (A) (preferably 0.01 to 10 wt%, more preferably 0.1 to 7 wt%, more preferably 0.2 to 5 wt%, even more preferably 0.3 to 4 wt%, still more preferably 0.4 to 3.5 wt%, 1 to 5 wt%, or 0.4 to 5 wt%).

[0026]

[19] The composition according to any one of [1] to

[18] , containing 0.05 to 2 wt % (preferably 0.1 to 1.5 wt %, more preferably 0.15 to 1 wt %, even more preferably 0.15 to 0.8 wt %, and still more preferably 0.2 to 0.4 wt %) of component (B).

[0027]

[20] The composition according to any one of [1] to

[19] , containing 0.01 to 10 wt % (preferably 0.01 to 8 wt %, more preferably 0.03 to 4 wt %, more preferably 0.1 to 4 wt %, even more preferably 0.1 to 2 wt %, and still more preferably 0.2 to 0.8 wt %) of component (C).

[0028]

[21] The composition according to any one of [1] to

[20] , containing 0.1 to 50% by weight (preferably 1 to 30% by weight, more preferably 2 to 25% by weight, more preferably 3 to 23% by weight, even more preferably 4 to 20% by weight, still more preferably 5 to 16% by weight, or 5 to 8% by weight) of component (E).

[0029]

[22] The composition according to any one of [1] to

[21] , containing 20 to 99% by weight (preferably 30 to 99% by weight, more preferably 40 to 99% by weight, more preferably 50 to 99% by weight, even more preferably 60 to 95% by weight, and even more preferably 70 to 90% by weight) of component (F).

[0030]

[23] The composition according to any one of [1] to

[22] , wherein component (E) contains component (G) selected from a non-crystalline high melting point oil agent having a melting point of 30°C or higher; a gelling agent for oil-based components; a silicone feel improver; and a mixture thereof.

[0031]

[24] Component (G) is A non-crystalline high melting oil having a melting point of 30°C or higher selected from the group consisting of non-crystalline triglycerides having a melting point of 30°C or higher, non-crystalline fatty acid sterol esters having a melting point of 30°C or higher, petrolatum, and mixtures thereof; a gelling agent for oily components selected from fatty acid inulin, fatty acid dextrin, polyglycerin, dibutyl ethylhexanoyl glutamide, dibutyl lauroyl glutamide, sodium dilauroyl glutamate lysine, (vinyl dimethicone / methicone silsesquioxane) crosspolymer, PEG / PPG-19 / 19 dimethicone, and mixtures thereof; a silicone feel modifier selected from amino modified silicones, silicone waxes, polyether modified silicones, highly polymerized dimethicones, silicone waxes, silicone emulsions, silicone powders, and mixtures thereof; and The mixture The composition according to any one of claims 23 to 24, wherein the composition is selected from the group consisting of

[0032]

[25] The composition according to

[23] or

[24] , wherein component (G) is selected from the group consisting of caprylic / capric / myristic / stearic triglyceride, Theobroma grandiflorum seed butter, di(octyldodecyl / phytosteryl / behenyl) lauroyl glutamate, fatty acid inulin (e.g., inulin stearate), fatty acid dextrin (e.g., dextrin myristate), amino-modified silicone (e.g., aminopropyl dimethicone), silicone wax (e.g., stearyl dimethicone), and mixtures thereof.

[0033]

[26] The composition according to any one of

[23] to

[25] , wherein the component (G) is selected from the group consisting of caprylic / capric / myristic / stearic triglyceride, Theobroma grandiflorum seed butter, di(octyldodecyl / phytosteryl / behenyl) lauroyl glutamate, and mixtures thereof.

[0034]

[27] The composition according to any one of

[23] to

[25] , wherein component (G) is selected from fatty acid inulin (e.g., stearate inulin), fatty acid dextrin (e.g., myristate dextrin), and a mixture thereof.

[0035]

[28] The composition according to any one of

[23] to

[25] , wherein the component (G) is selected from amino-modified silicones (e.g., aminopropyl dimethicone), silicone waxes (e.g., stearyl dimethicone), and mixtures thereof.

[0036]

[29] The composition according to any one of

[23] to

[28] , wherein component (E) contains component (G) in an amount of 0.1 to 50% by weight (preferably 1 to 30% by weight, and more preferably 2.5 to 25% by weight).

[0037]

[30] The composition according to any one of

[23] to

[26] and

[29] , wherein component (G) is a non-crystalline high melting point oil having a melting point of 30°C or higher, and component (E) contains component (G) in an amount of 0.01 to 50% by weight (preferably 0.1 to 40% by weight, and more preferably 6 to 25% by weight).

[0038]

[31] The composition according to any one of

[23] to

[25] ,

[27] , and

[29] , wherein component (G) is a gelling agent for the oily component, and component (E) contains component (G) in an amount of 0.01 to 50% by weight (preferably 0.1 to 20% by weight, and more preferably 2.5 to 6.25% by weight).

[0039]

[32] The composition according to any one of

[23] to

[25] ,

[28] , and

[29] , wherein component (G) is the silicone feel improver, and component (E) contains component (G) in an amount of 0.01 to 50% by weight (preferably 0.1 to 20% by weight, more preferably 0.5 to 15% by weight, and further preferably 1 to 10% by weight).

[0040]

[33] The composition according to any one of

[23] to

[32] , containing 0.001 to 10 wt % (preferably 0.01 to 10 wt %, more preferably 0.1 to 7 wt %, more preferably 0.1 to 5 wt %, even more preferably 0.2 to 3 wt %, and still more preferably 0.2 to 2 wt %) of component (G).

[0041]

[34] Ingredient (H): Water-soluble moisturizer The composition according to any one of [1] to

[33] , further comprising:

[0042]

[35] The composition according to any one of [1] to

[34] , wherein component (H) is a water-soluble moisturizer selected from low-polarity polyhydric alcohols (e.g., butylene glycol, bisethoxydiglycol cyclohexane-1,4-dicarboxylate, dipropylene glycol, PEG / PPG / polybutylene glycol-8 / 5 / 3 glycerin, POE methyl glucoside), sugars (e.g., glyceryl glucoside, diglycerin, trehalose, sorbitol fermentation polysaccharide liquid), film-forming agents (e.g., pullulan, PVP, gum arabic), and mixtures thereof.

[0043]

[36] Component (A): Adenosine phosphate and / or its salt; Component (B): (acrylates / C10-30 alkyl acrylate) crosspolymer; Component (C): Crosslinked sodium polyacrylate and / or (PEG-240 / Decyltetradeceth-20 / HDI) copolymer (preferably crosslinked sodium polyacrylate); Ingredient (E): Oil; and Ingredient (F): Water, The composition according to any one of [1] to

[35] , having a viscosity of 1,500 to 8,000 mPa s.

[0044]

[37] The composition according to

[36] , wherein the weight ratio of component (C) / (component (A)+component (B)) is 0.04 to 0.7.

[0045]

[38] Component (A): adenosine phosphate and / or a salt thereof 1.5 to 3.5% by weight; Component (B): (acrylates / C10-30 alkyl acrylate) crosspolymer 0.2 to 0.4% by weight; Component (C): 0.04 to 0.8% by weight of crosslinked sodium polyacrylate and / or (PEG-240 / Decyltetradeceth-20 / HDI) copolymer (preferably crosslinked sodium polyacrylate); Component (E): oil content 5 to 8% by weight; and Ingredient (F): Water, The composition according to any one of [1] to

[37] , having a viscosity of 1,500 to 8,000 mPa s.

[0046]

[39] Component (A): Adenosine phosphate and / or its salt; Component (B): (acrylates / C10-30 alkyl acrylate) crosspolymer; Component (D): tromethamine and / or arginine; Ingredient (E): Oil; and Ingredient (F): Water, The composition according to any one of [1] to

[38] , having a viscosity of 1,500 to 8,000 mPa s and a pH of 6 to 7.

[0047]

[40] Component (A): adenosine phosphate and / or a salt thereof 1.5 to 3.5% by weight; Component (B): (acrylates / C10-30 alkyl acrylate) crosspolymer 0.2-0.4% by weight; Component (D): tromethamine, aminomethylpropanediol, and / or arginine; Component (E): oil content 5 to 8% by weight; and Ingredient (F): Water, The composition according to any one of [1] to

[39] , having a viscosity of 1,500 to 8,000 mPa s and a pH of 6 to 7.

[0048]

[41] The composition according to any one of [1] to

[40] , which is a lotion; an emulsion selected from an emollient emulsion, a milky lotion, a nourishing emulsion, and a cleansing emulsion; a cream selected from an emollient cream, a massage cream, a cleansing cream, and a makeup cream; or a lip cream.

[0049]

[42] The composition according to any one of [1] to

[41] , which is applied or sprayed onto the skin.

[0050]

[43] A method for producing an O / W type emulsion composition having a viscosity of less than 10,000 mPa s, comprising mixing component (A), component (B), component (E), and component (F) in the presence of component (C) and / or component (D): Component (A): Adenosine phosphate and / or its salt; Component (B): acrylic acid-alkyl methacrylate copolymer; Component (C): a water-soluble polymer selected from a swelling type thickener, an associative type thickener, a polysaccharide and its derivatives, and a mixture thereof; Component (D): pH adjuster which is an organic alkali; Ingredient (E): Oil; Ingredient (F): Water.

[0051]

[44] A method for improving emulsion stability of an O / W type emulsion composition containing components (A), (B), (E), and (F) and having a viscosity of less than 10,000 mPa s, comprising adding component (C) and / or component (D): Component (A): Adenosine phosphate and / or its salt; Component (B): acrylic acid-alkyl methacrylate copolymer; Component (C): a water-soluble polymeric polysaccharide and its derivative selected from a swelling type thickener, an associative type thickener, a polysaccharide and its derivative, and a mixture thereof; Component (D): pH adjuster which is an organic alkali; Ingredient (E): Oil; Ingredient (F): Water.

[0052]

[45] A method for improving the usability of an O / W type emulsion composition containing components (A), (B), (E), and (F) and having a viscosity of less than 10,000 mPa s, comprising adding component (C) and / or component (D): Component (A): Adenosine phosphate and / or its salt; Component (B): acrylic acid-alkyl methacrylate copolymer; Component (C): a water-soluble polymer selected from a swelling type thickener, an associative type thickener, a polysaccharide and its derivatives, and a mixture thereof; Component (D): pH adjuster which is an organic alkali; Ingredient (E): Oil; Ingredient (F): Water.

[0053] [Section 1] An O / W type emulsion composition comprising component (A), component (B), component (E), and component (F), and also containing component (C) and / or component (D), and having a viscosity of less than 10,000 mPa s: Component (A): Adenosine phosphate and / or its salt; Component (B): acrylic acid-alkyl methacrylate copolymer; Component (C): a water-soluble polymer selected from a swelling type thickener, an associative type thickener, a polysaccharide and its derivatives, and a mixture thereof; Component (D): pH adjuster which is an organic alkali; Ingredient (E): Oil; Ingredient (F): Water. [Section 2] Item 2. The composition according to item 1, wherein component (B) is an acrylic acid / alkyl methacrylate copolymer having a molecular weight of 100,000 to 5,000,000. [Section 3] Component (C) is a swelling type thickener selected from sodium polyacrylate, ammonium polyacrylate, ammonium polyacrylate, acrylamide / sodium acrylate copolymer, vinylpyrrolidone / 2-acrylamido-2-methylpropanesulfonic acid copolymer, mixtures of polyacrylic acid amide and sodium polyacrylate, sodium acrylate / 2-acrylamido-2-methylpropanesulfonic acid copolymer, hydroxyethyl acrylate / 2-acrylamido-2-methylpropanesulfonic acid copolymer and mixtures thereof; a urethane associative thickener selected from PEG-240 / Decyltetradeceth-20 / HDI copolymer, PEG-150 / Stearyl alcohol / SMDI copolymer, PEG-150 / Decyl alcohol / SMDI copolymer, Polyurethane-59, and mixtures thereof; and Item 3. The composition according to item 1 or 2, wherein the water-soluble polymer is selected from the mixture. [Section 4] The composition according to any one of items 1 to 3, wherein component (D) is a pH adjuster that is an organic alkali selected from tromethamine, aminomethylpropanediol, aminomethylpropanol, arginine, and mixtures thereof. [Section 5] 5. The composition according to any one of items 1 to 4, comprising component (C) and having a weight ratio of component (C) / component (A) of 0.01 to 30. [Section 6] 6. The composition according to any one of items 1 to 5, further comprising a component (C), and a weight ratio of component (C) / (component (A)+component (B)) is 0.005 to 20. [Section 7] 7. The composition according to any one of items 1 to 6, comprising component (C) and having a component (C) / component (B) (weight ratio) of 0.05 to 60. [Section 8] Item 8. The composition according to any one of items 1 to 7, having a pH of 5.5 to 7.5. [Section 9] Component (A): Adenosine phosphate and / or its salt; Component (B): (acrylates / C10-30 alkyl acrylate) crosspolymer; Component (C): Crosslinked sodium polyacrylate and / or (PEG-240 / Decyltetradeceth-20 / HDI) copolymer; Ingredient (E): Oil; and Ingredient (F): Water, and having a viscosity of 1,500 to 10,000 mPa·s. [Section 10] Component (A): Adenosine phosphate and / or its salt; Component (B): (acrylates / C10-30 alkyl acrylate) crosspolymer; Component (D): tromethamine and / or arginine; Ingredient (E): Oil; and Ingredient (F): Water, 10. The composition according to any one of items 1 to 9, having a viscosity of 1,500 to 10,000 mPa·s and a pH of 6 to 7. [Section 11] Contains 0.001 to 10% by weight of component (A), Contains 0.05 to 2% by weight of component (B), Contains 0.1 to 50% by weight of component (E); The composition according to any one of items 1 to 10. [Section 12] 12. The composition according to any one of items 1 to 11, comprising 0.01 to 10% by weight of component (C). [Section 13] Component (A): 0.4 to 3.5% by weight of adenosine phosphate and / or a salt thereof; Component (B): (acrylates / C10-30 alkyl acrylate) crosspolymer 0.2 to 0.4% by weight; Component (C): Cross-linked sodium polyacrylate and / or (PEG-240 / Decyltetradeceth-20 / HDI) copolymer 0.04-0.8% by weight; Component (E): oil content 5 to 8% by weight; and Ingredient (F): Water, and having a viscosity of 1,500 to 10,000 mPa·s. [Section 14] Component (A): 0.4 to 3.5% by weight of adenosine phosphate and / or a salt thereof; Component (B): (acrylates / C10-30 alkyl acrylate) crosspolymer 0.2-0.4% by weight; Component (D): tromethamine, aminomethylpropanediol, and / or arginine; Component (E): oil content 5 to 8% by weight; and Ingredient (F): Water, Item 14. The composition according to any one of items 1 to 13, comprising: [Section 15] Does not contain inorganic alkaline pH adjusters or 15. The composition according to any one of items 1 to 14, further comprising an inorganic alkaline pH adjuster, and the inorganic alkaline pH adjuster / component (D) (weight ratio) is 0.1 or less. [Section 16] Component (E) is A non-crystalline high melting oil having a melting point of 30°C or higher selected from the group consisting of non-crystalline triglycerides having a melting point of 30°C or higher, non-crystalline fatty acid sterol esters having a melting point of 30°C or higher, petrolatum, and mixtures thereof; a gelling agent for oily components selected from fatty acid inulin, fatty acid dextrin, polyglycerin, dibutyl ethylhexanoyl glutamide, dibutyl lauroyl glutamide, sodium dilauroyl glutamate lysine, (vinyl dimethicone / methicone silsesquioxane) crosspolymer, PEG / PPG-19 / 19 dimethicone, and mixtures thereof; a silicone feel modifier selected from amino modified silicones, silicone waxes, polyether modified silicones, highly polymerized dimethicones, silicone waxes, silicone emulsions, silicone powders, and mixtures thereof; and The mixture 16. The composition according to any one of items 1 to 15, comprising a component (G) selected from the following, and component (E) contains 0.1 to 50% by weight of component (G). [Section 17] 17. The composition according to any one of items 1 to 16, comprising 0.1 to 5% by weight of component (G). [Section 18] Ingredient (H): Water-soluble moisturizer Item 18. The composition according to any one of items 1 to 17, further comprising: Effect of the Invention

[0054] The present invention provides an O / W type emulsion composition with good emulsion stability and low viscosity (less than 10,000 mPa s) containing adenosine phosphate and / or its salt and acrylic acid / alkyl methacrylate copolymer. Furthermore, the feel of the composition when used can be improved by adding a non-crystalline high melting point oil with a melting point of 30°C or higher, a gelling agent for oily components, and / or a silicone feel improver.

[0055] In one embodiment, the present disclosure provides an O / W type emulsion composition (hereinafter, may be referred to as the “composition of the present invention”) comprising component (A), component (B), component (E), and component (F), and further comprising component (C) and / or component (D), and having a viscosity of less than 10,000 mPa s: Component (A): Adenosine phosphate and / or its salt; Component (B): acrylic acid-alkyl methacrylate copolymer; Component (C): a water-soluble polymer selected from a swelling type thickener, an associative type thickener, a polysaccharide and its derivatives, and a mixture thereof; Component (D): pH adjuster which is an organic alkali; Ingredient (E): Oil; Ingredient (F): Water.

[0056] By adding component (C) and / or component (D), the emulsion stability and / or usability of a low-viscosity O / W type emulsion composition containing adenosine phosphate and / or a salt thereof and an acrylic acid / alkyl methacrylate copolymer can be improved.

[0057] In the present application, the term "O / W type emulsion composition" refers to an emulsion composition in which oil is dispersed in an aqueous phase. The method for testing whether an emulsion composition is O / W type is not particularly limited, and it can be tested by commonly used methods (e.g., dispersion method, electrical conductivity method, dye method, dilution method, and refractive index method).

[0058] In one embodiment, the viscosity of the composition of the present invention is less than 10,000 mPa·s. Preferred viscosity ranges of the composition of the present application may vary depending on the application, form, etc., and include 200 to 10,000 mPa·s, 300 to 9,000 mPa·s, 500 to 8,000 mPa·s, 1,000 to 5,000 mPa·s, and 1,500 to 3,000 mPa·s. Furthermore, examples of the lower limit of the viscosity of the composition of the present invention include 200 mPa·s, 300 mPa·s, 500 mPa·s and 800 mPa·s, and examples of the upper limit include 1,000 mPa·s, 2,000 mPa·s, 3,000 mPa·s, 4,000 mPa·s, 5,000 mPa·s, 6,000 mPa·s, 7,000 mPa·s, 8,000 mPa·s, 9,000 mPa·s and 10,000 mPa·s, and preferred examples of the range can be represented by a combination of the lower limit and the upper limit.

[0059] In the present disclosure, the viscosity of the composition is measured using a single cylindrical rotational viscometer (B-type viscometer, Tokyo Keiki BM type) with rotor No. 1 to 4 under conditions of 25°C, 12 rpm or 30 rpm, and 1 minute. Alternatively, it may be measured by a method equivalent to the above method.

[0060] In the present application, examples of adenosine phosphate include adenosine monophosphate (adenosine 2' monophosphate, adenosine 3' monophosphate, adenosine 5' monophosphate, etc.), adenosine diphosphate (adenosine 5' diphosphate, etc.), adenosine triphosphate (adenosine 5' triphosphate, etc.), adenosine 3',5' cyclic phosphate, etc.), which may be used alone or in any combination of two or more kinds.

[0061] In the present application, the adenosine phosphate salt is not particularly limited as long as it can be incorporated into cosmetics, external medicines or quasi-drugs.Specific examples of the adenosine phosphate salt include alkali metal salts such as sodium salt and potassium salt; alkaline earth metal salts such as calcium salt, magnesium salt and barium salt; basic amino acid salts such as arginine and lysine; ammonium salts such as ammonium salt and tricyclohexylammonium salt; various alkanolamine salts such as monoethanolamine salt, diethanolamine salt, triethanolamine salt, monoisopropanolamine salt, diisopropanolamine salt and triisopropanolamine salt.The adenosine phosphate salt may be used alone or in any combination of two or more.

[0062] The amount of component (A) contained in the composition of the present invention varies depending on the use and form of the composition, but can be appropriately selected, for example, from the range of 0.001 to 10% by weight based on the total weight of the composition. Examples of preferred ranges include 0.01 to 10% by weight, more preferably 0.1 to 7% by weight, more preferably 0.2 to 5% by weight, even more preferably 0.3 to 4% by weight, and even more preferably 0.4 to 3.5% by weight. Examples of more preferred ranges include 1 to 5% by weight and 0.4 to 5% by weight. Furthermore, examples of lower limits of the range of the amount of component (A) contained in the composition of the present invention include 0.001 weight%, 0.01 weight%, 0.1 weight%, 0.3 weight%, 0.4 weight%, 0.5 weight%, 0.7 weight%, and 1 weight%, and examples of upper limits include 1 weight%, 2 weight%, 3 weight%, 3.5 weight%, 4 weight%, 5 weight%, 7 weight%, and 10 weight%, and preferred examples of the range can be represented by a combination of the lower limit and the upper limit.

[0063] In the present application, the acrylic acid alkyl methacrylate copolymer is not particularly limited, but examples thereof include acrylic acid alkyl methacrylate copolymers having a molecular weight of 100,000 to 5,000,000. Examples of acrylic acid alkyl methacrylate copolymers include acrylic acid alkyl methacrylate copolymers having an alkyl group with 8 to 35 carbon atoms, more preferably acrylic acid alkyl methacrylate copolymers having 10 to 30 carbon atoms (e.g., (acrylates / alkyl acrylate (C10-30)) crosspolymers, etc.). In addition, these structures are not limited and are appropriately selected depending on the purpose. In the composition of the present invention, one type of acrylic acid alkyl methacrylate copolymer may be used alone, or two or more types of acrylic acid alkyl methacrylate copolymers may be used in combination.

[0064] The amount of component (B) contained in the composition of the present invention varies depending on the application and form of the composition, but can be appropriately selected, for example, from the range of 0.05 to 2% by weight relative to the total weight of the composition, more preferably 0.1 to 1.5% by weight, more preferably 0.15 to 1% by weight, even more preferably 0.15 to 0.8% by weight, and even more preferably 0.2 to 0.4% by weight. Furthermore, examples of lower limits of the range of the amount of component (B) contained in the composition of the present invention include 0.05, 0.1 weight%, 0.15 weight%, and 0.2 weight%, and examples of upper limits include 0.4 weight%, 0.6 weight%, 0.7 weight%, 0.8 weight%, 1 weight%, 1.5 weight%, and 2 weight%, and preferred examples of the range can be represented by a combination of the lower limit and the upper limit.

[0065] Examples of the water-soluble polymer of component (C) that may be contained in the composition of the present invention include swelling type thickeners, associative type thickeners, polysaccharides and derivatives thereof, and these may be used alone or in any combination of two or more.

[0066] Examples of swelling type thickeners include alkali swelling type thickeners, such as sodium polyacrylate (e.g., cross-linked sodium polyacrylate), ammonium polyacrylate, acrylamide / sodium acrylate copolymer, vinylpyrrolidone / 2-acrylamido-2-methylpropanesulfonic acid copolymer, mixtures of polyacrylic acid amide and sodium polyacrylate, sodium acrylate / 2-acrylamido-2-methylpropanesulfonic acid copolymer, and hydroxyethyl acrylate / 2-acrylamido-2-methylpropanesulfonic acid copolymer. These may be used alone or in any combination of two or more.

[0067] Examples of associative thickeners include polyacrylic acid associative thickeners: for example, acrylic acid copolymers, (acrylates / vinyl neodecanoate) crosspolymers, ((acrylates / steareth-20 methacrylate) crosspolymers, (acrylates / steareth-20 methacrylate) copolymers, (acrylates / beheneth-25 methacrylate) copolymers, (acrylates / steareth-20 itaconate) copolymers), etc.; polyvinyl alcohol; polyvinyl thickeners; polyether associative thickeners. Polyglycol-based associative thickeners, maleic anhydride copolymer-based associative thickeners, polyamide-based associative thickeners, polyester-based associative thickeners, hydrophobized cellulose ester-based associative thickeners, urethane associative thickeners, such as (PEG-240 / decyltetradeceth-20 / HDI) copolymer, (PEG-150 / stearyl alcohol / SMDI) copolymer, (PEG-150 / decyl alcohol / SMDI) copolymer, polyurethane-59, and polycarboxylic acid associative thickeners. These may be used alone or in any combination of two or more.

[0068] Examples of polysaccharides and derivatives thereof include cationized xanthan gum, cationized cellulose, xanthan gum, guar gum, carrageenan, tamarind gum, quince seed gum, sclerotium gum, hydroxypropyl starch phosphate, and agar. These may be used alone or in any combination of two or more.

[0069] In the composition of the present invention, the amount of component (C) is not particularly limited as long as the emulsifiability of the composition is stable and / or the composition exhibits a good feeling of use, but the weight ratio of component (C) to component (A) (component (C) / component (A)) is, for example, 0.01 to 30, preferably 0.01 to 20, more preferably 0.02 to 10, more preferably 0.03 to 5, and even more preferably 0.04 to 0.8. Another preferred range is 0.1 to 0.5. Furthermore, examples of the lower limit of component (C) / component (A) (weight ratio) include 0.01, 0.02, 0.03, 0.04, 0.1, 0.2, and 0.5, and examples of the upper limit include 0.5, 0.8, 1, 1.5, 2, 3, 5, 10, 20, and 30, and preferred examples of the range can be represented by a combination of the lower limit and the upper limit.

[0070] In the composition of the present invention, the amount of component (C) is, for example, the weight ratio of component (C) to the total of components (A) and (B) (component (C) / (component (A)+component (B)) is 0.005 to 20, preferably 0.01 to 10, more preferably 0.02 to 5, even more preferably 0.01 to 1.5, and even more preferably 0.04 to 0.7. Another preferred range is 0.1 to 0.3. Furthermore, examples of the lower limit of component (C) / (component (A)+component (B) (weight ratio) include 0.005, 0.01, 0.02, 0.03, 0.04, and 0.1, and examples of the upper limit include 0.3, 0.7, 1, 1.5, 2, and 5. Preferred examples of the range can be represented by a combination of the lower limit and the upper limit.

[0071] In the composition of the present invention, the amount of component (C) is not particularly limited as long as the emulsifiability of the composition is stable and / or the composition exhibits a good feeling of use, but the weight ratio of component (C) to component (B) (component (C) / component (B)) is, for example, 0.05 to 60, preferably 0.1 to 30, more preferably 0.1 to 20, even more preferably 0.1 to 10, even more preferably 0.1 to 5, and even more preferably 0.5 to 4. Another preferred range is 0.3 to 1. Furthermore, examples of the lower limit of component (C) / component (B) (weight ratio) include 0.05, 0.1, 0.2, 0.3, 0.5, and 1, and examples of the upper limit include 60, 30, 20, 15, 10, 8, 5, 4, 3, 2, and 1, and preferred examples of the range can be represented by a combination of the lower limit and the upper limit.

[0072] The amount of component (C) contained in the composition of the present invention can be appropriately selected, for example, from the range of usually 0.01 to 10% by weight relative to the total weight of the composition, preferably 0.01 to 8% by weight, more preferably 0.03 to 4% by weight, more preferably 0.1 to 4% by weight, even more preferably 0.1 to 2% by weight, and even more preferably 0.2 to 0.8% by weight. Furthermore, examples of lower limits of the range of the amount of component (C) contained in the composition of the present invention include 0.001 weight%, 0.01 weight%, 0.03 weight%, 0.1 weight%, and 0.2 weight%, and examples of upper limits include 10 weight%, 7 weight%, 5 weight%, 3 weight%, 2 weight%, 1 weight%, and 0.8 weight%, and preferred examples of the range can be represented by a combination of the lower limit and the upper limit.

[0073] Examples of the organic alkali pH adjuster of component (D) include tromethamine, aminomethylpropanediol, aminomethylpropanol, and arginine. These may be used alone or in any combination of two or more.

[0074] The preferred pH of the composition of the present invention varies depending on the application of the composition, and may be, for example, pH 5.5 to 7.5 (preferably pH 6 to 7, e.g., pH 6.5 to 7). To adjust the pH of the composition of the present invention, a pH adjuster other than component (D) (e.g., inorganic alkali pH adjuster (e.g., potassium hydroxide, sodium hydroxide)) may be used within a range in which the effect on emulsion stability and / or usability is not a problem. When component (D) and an inorganic alkali are used together, the weight ratio of the inorganic alkali pH adjuster to component (D) in the composition of the present invention (inorganic alkali pH adjuster / component (D)) is preferably 0.1 or less (more preferably 0.01 or less). In one embodiment, an organic alkali may be used in the composition of the present invention from the viewpoint of suppressing discoloration and / or odor change over time of the composition.

[0075] In the composition of the present invention, the amount of component (D) is not particularly limited as long as the emulsion stability and / or usability of the composition are good, and varies depending on the amount of component (A), the types and amounts of other components, and the preferred pH of the composition. For example, the weight ratio of component (D) to component (A) (component (D) / component (A)) is 0.01 to 50 (e.g., 0.05 to 40, 0.1 to 30, 0.1 to 20, 0.1 to 10). Furthermore, examples of the lower limit of component (D) / component (A) (weight ratio) include 0.01, 0.05, and 0.1, and examples of the upper limit include 2, 5, 10, 20, 40, and 50, and preferred examples of the range can be represented by a combination of the lower limit and the upper limit.

[0076] In the composition of the present invention, the oil content of component (E) is not particularly limited. in particular, Fats and oils such as vegetable oils such as peanut oil, sesame oil, soybean oil, safflower oil, avocado oil, sunflower oil, corn oil, rapeseed oil, menju oil, castor oil, camellia oil, coconut oil, olive oil, poppy seed oil, cacao oil, and jojoba oil, and animal fats and oils such as beef tallow, lard, and wool oil; Hydrocarbon liquid oils such as Vaseline, liquid paraffin, squalane, hydrogenated polyisobutene, and α-olefin oligomers; Higher fatty acid esters such as isopropyl myristate, isopropyl isostearate, myristyl myristate, cetyl ethylhexanoate, cetyl palmitate, cetyl isooctanoate, isocetyl myristate, n-butyl myristate, octyldodecyl myristate, isopropyl linoleate, propyl ricinoleate, isopropyl ricinoleate, pentaerythritol tetraoctanoate, isobutyl ricinoleate, heptyl ricinoleate, diethyl sebacate, and diisopropyl adipate; fatty acid sterol esters such as phytosteryl isostearate and di(phytosteryl / octyldodecyl) lauroyl glutamate; lanolins and derivatives thereof such as lanolin, liquid lanolin, and lanolin wax; waxes such as white beeswax, spermaceti, and wood wax; Higher fatty alcohols such as cetyl alcohol, stearyl alcohol, behenyl alcohol, batyl alcohol, and chimyl alcohol; Waxes; Higher fatty acids such as stearic acid, oleic acid, and palmitic acid; Mixture of mono-, di- and triglycerides of saturated or unsaturated fatty acids having 12 to 18 carbon atoms; Examples of the silicone oil include chain silicones such as methylpolysiloxane, dimethylpolysiloxane, methylphenylpolysiloxane, and methylhydrogenpolysiloxane; cyclic silicones such as cyclopentasiloxane, decamethylcyclopentasiloxane, octamethylcyclotetrasiloxane, and methylcyclosiloxane; crosslinked silicones such as crosslinked methylpolysiloxane and crosslinked methylphenylpolysiloxane; and modified silicones modified with, for example, polyoxyethylene or polyoxypropylene.

[0077] The amount of component (E) contained in the composition of the present invention can be appropriately selected, for example, from the range of usually 0.1 to 50% by weight relative to the total weight of the composition, preferably 1 to 30% by weight, more preferably 2 to 25% by weight, more preferably 3 to 23% by weight, even more preferably 4 to 20% by weight, and even more preferably 5 to 16% by weight, 5 to 8% by weight, for example. Furthermore, examples of lower limits of the range of the amount of component (E) contained in the composition of the present invention include 0.1 weight%, 1 weight%, 2 weight%, 3 weight%, 4 weight%, and 5 weight%, and examples of upper limits include 50 weight%, 30 weight%, 27 weight%, 25 weight%, 23 weight%, 20 weight%, and 16 weight%, and preferred examples of the range can be represented by a combination of the lower limit and the upper limit.

[0078] In the composition of the present invention, component (E) may contain component (G) selected from a non-crystalline high melting point oil agent having a melting point of 30° C. or higher, a gelling agent for oily components, a silicone feel improver, and mixtures thereof. By blending component (G) in the composition of the present invention, the usability of the composition of the present invention can be further improved.

[0079] By blending a non-crystalline high melting point oil having a melting point of 30° C. or higher in the composition of the present invention, the thickness and richness of the composition when used can be improved, while the stickiness is unexpectedly alleviated and the freshness can be improved. It is usually difficult to ensure emulsion stability when blending a high melting point oil in an emulsion composition containing a polymer emulsifier, but by selecting a non-crystalline high melting point oil, it can be easily blended in the emulsion composition.

[0080] Examples of non-crystalline high melting point oils include: Non-crystalline triglycerides with a melting point of 30°C or higher: for example, tri(caprylic / capric / myristic / stearic)glyceryl, Theobroma grandiflorum seed butter, shea butter, hydrogenated palm oil, hydrogenated jojoba oil, jojoba butter, cocoa butter, palm oil, palm kernel oil, hardened oil, coconut oil fatty acid, PEG-60 almond fatty acid glyceryl, African mango kernel butter, hydrogenated cocoglyceryl, lanolin fatty acid; Vaseline; Non-crystalline fatty acid sterol esters having a melting point of 30°C or higher: for example, macadamia nut fatty acid phytosteryl, polyoxyethylene phytosterol (5E.O.), sunflower seed oil fatty acid phytosteryl, lauroyl glutamate di(octyldodecyl / phytosteryl / behenyl), dimer dilinoleyl dimer dilinoleate bis(behenyl / isostearyl / phytosteryl), dimer dilinoleate (phytosteryl / isostearyl / cetyl / stearyl / behenyl), (raspberry seed oil / tocopherol succinate) aminopropanediol esters, adipate diglyceryl mixed fatty acid esters, bisdiglyceryl polyacyladipate-2), Examples include: These may be used alone or in any combination of two or more.

[0081] By blending a gelling agent for oily components in the composition of the present invention, the thickness and richness of the composition when used can be improved, while the stickiness can be surprisingly alleviated and the freshness can be improved. By blending a gelling agent for oily components, the viscosity of the oil phase can be increased, and the oil release after application of the composition of the present invention can be delayed to adjust the spreadability of the oil, and not only thickness and smoothness but also a fresh feel can be imparted.

[0082] Examples of gelling agents for oily components include fatty acid inulin (e.g., stearate inulin), fatty acid dextrin (e.g., myristate dextrin), polyglycerin, dibutyl ethylhexanoyl glutamide, dibutyl lauroyl glutamide, sodium dilauroyl glutamate lysine, (vinyl dimethicone / methicone silsesquioxane) crosspolymer, hydrogenated polydecene, hydrogenated (styrene / isoprene) copolymer, silylated silica, and PEG / PPG-19 / 19 dimethicone. These may be used alone or in any combination of two or more.

[0083] By incorporating a silicone feel improver into the composition of the present invention, the feel of the composition when used can be reduced to a less sticky state, increased freshness, and unexpectedly improved body and thickness.

[0084] Examples of silicone feel improvers include amino-modified silicones (e.g., aminopropyl dimethicone), silicone waxes (e.g., stearyl dimethicone, bisPEG-18 methyl ether dimethyl silane, alkyl (C26-28) dimethicone, alkyl (C26-28) methicone, bisstearoxydimethylsilane, (acrylates / stearyl acrylate / dimethicone methacrylate) copolymer, (acrylates / behenyl acrylate / dimethicone methacrylate) copolymer), polyether-modified silicones, highly polymerized dimethicone, silicone wax, silicone emulsion, and silicone powder. These may be used alone or in any combination of two or more.

[0085] The amount of component (G) is not particularly limited as long as the emulsion stability and / or usability of the composition are good. For example, component (G) is contained in an amount of 0.1 to 50% by weight, preferably 1 to 30% by weight, and more preferably 2.5 to 25% by weight, per 100% by weight of component (E). Furthermore, examples of the lower limit of the range of the amount of component (G) contained in 100% by weight of component (E) include 0.1% by weight, 0.5% by weight, 1% by weight, 2% by weight, 2.5% by weight, and 5% by weight, and examples of the upper limit of the range include 50% by weight, 40% by weight, 35% by weight, 30% by weight, and 25% by weight, and preferred examples of the range can be represented by a combination of the lower limit and the upper limit.

[0086] Furthermore, when component (G) is a non-crystalline high melting point oil having a melting point of 30°C or higher, the amount of component (G) is, for example, 0.01 to 50 wt%, preferably 0.1 to 40 wt%, and more preferably 6 to 25 wt%, per 100 wt% of component (E). Furthermore, examples of the lower limit of the range of the amount of component (G) contained in 100% by weight of component (E) include 0.01% by weight, 0.02% by weight, 0.1% by weight, 1% by weight, 3% by weight, and 6% by weight, and examples of the upper limit of the range include 50% by weight, 40% by weight, 30% by weight, and 25% by weight, and preferred examples of the range can be represented by a combination of the lower limit and the upper limit.

[0087] Furthermore, when component (G) is a gelling agent for oily components, the amount of component (G) is, for example, 0.01 to 50% by weight, preferably 0.1 to 20% by weight, and more preferably 2.5 to 6.25% by weight, per 100% by weight of component (E). Furthermore, examples of the lower limit of the range of the amount of component (G) contained in 100% by weight of component (E) include 0.01% by weight, 0.1% by weight, 0.5% by weight, 1% by weight, 2% by weight, and 2.5% by weight, and examples of the upper limit of the range include 50% by weight, 30% by weight, 20% by weight, 10% by weight, and 6.25% by weight, and preferred examples of the range can be represented by a combination of the lower limit and the upper limit.

[0088] Furthermore, when component (G) is a silicone feel improver, the amount of component (G) is, for example, 0.01 to 50% by weight, preferably 0.1 to 20% by weight, more preferably 0.5 to 15% by weight, and even more preferably 1 to 10% by weight, per 100% by weight of component (E). Furthermore, examples of the lower limit of the range of the amount of component (G) contained in 100% by weight of component (E) include 0.01% by weight, 0.1% by weight, 0.5% by weight, 1% by weight, 2% by weight, and 3% by weight, and examples of the upper limit of the range include 50% by weight, 30% by weight, 20% by weight, 15% by weight, and 10% by weight, and preferred examples of the range can be represented by a combination of the lower limit and the upper limit.

[0089] The amount of component (G) that can be contained in the composition of the present invention can be appropriately selected, for example, from the range of usually 0.001 to 10% by weight relative to the total weight of the composition, preferably 0.01 to 10% by weight, more preferably 0.1 to 7% by weight, more preferably 0.1 to 5% by weight, even more preferably 0.2 to 3% by weight, and even more preferably 0.2 to 2% by weight. Furthermore, examples of lower limits of the range of the amount of component (G) that can be contained in the composition of the present invention include 0.001 weight%, 0.01 weight%, 0.1 weight%, 0.2 weight%, 0.5 weight%, 0.7 weight%, and 1 weight%, and examples of upper limits include 1 weight%, 2 weight%, 2.5 weight%, 3 weight%, 5 weight%, 7 weight%, and 10 weight%, and preferred examples of the range can be represented by a combination of the lower limit and the upper limit.

[0090] The composition of the present invention may contain a water-soluble moisturizing agent (H). By incorporating a water-soluble moisturizing agent, the feeling of use of the composition of the present invention can be improved.

[0091] Examples of water-soluble moisturizing agents include low polarity polyhydric alcohols (e.g., butylene glycol, cyclohexane-1,4-dicarboxylate bisethoxydiglycol, dipropylene glycol, PEG / PPG / polybutylene glycol-8 / 5 / 3 glycerin, POE methyl glucoside), sugars (e.g., glyceryl glucoside, diglycerin, trehalose, sorbitol fermentation polysaccharide liquid), and film-forming agents (e.g., pullulan, PVP, gum arabic). These may be used alone or in any combination of two or more.

[0092] The amount of component (H) that can be contained in the composition of the present invention can be appropriately selected, for example, from the range of 0.001 to 50% by weight relative to the total weight of the composition, preferably 0.01 to 30% by weight, more preferably 0.1 to 20% by weight, and even more preferably 0.5 to 10% by weight. Furthermore, examples of lower limits of the range of the amount of component (H) that can be contained in the composition of the present invention include 0.001 weight%, 0.01 weight%, 0.1 weight%, 0.5 weight%, and 1 weight%, and examples of upper limits include 1 weight%, 2 weight%, 3 weight%, 5 weight%, 7 weight%, 10 weight%, 20 weight%, 25 weight%, and 30 weight%, and preferred examples of the range can be represented by a combination of the lower limit and the upper limit.

[0093] The amount of water (component (F)) contained in the composition of the present invention is not particularly limited and varies depending on the amounts of other components, but can be appropriately selected, for example, from the range of usually 20 to 99% by weight based on the total weight of the composition, preferably 30 to 99% by weight, more preferably 40 to 99% by weight, more preferably 50 to 99% by weight, even more preferably 60 to 95% by weight, and even more preferably 70 to 90% by weight. Furthermore, examples of the lower limit of the range of the amount of component (F) contained in the composition of the present invention include 20% by weight, 30% by weight, 40% by weight, 50% by weight, 60% by weight, and 70% by weight, and examples of the upper limit include 99% by weight, 95% by weight, and 90% by weight, and preferred examples of the range can be represented by a combination of the lower limit and the upper limit.

[0094] The compositions of the present invention may optionally contain a chelating agent (eg, edetate, etidronic acid, sodium polyphosphate, sodium metaphosphate).

[0095] Each component that can be incorporated in the composition of the present invention may be in the form of a hydrate.

[0096] The composition of the present invention can be prepared in various forms by combining pharma- ceutically or cosmetically acceptable bases and carriers in addition to the above-mentioned components. As the pharma-ceutically or cosmetically acceptable bases and carriers, conventionally known ones can be used. In addition, the composition of the present invention can be blended with various known components blended in external compositions applied to the skin or mucous membranes, such as cosmetics and external pharmaceuticals and quasi-drugs, as necessary. Examples of such ingredients include solvents (e.g., cyclomethicone, macadamiate phytosteryl, alkyl benzoate (C12-15), diethylaminohydroxybenzoyl hexyl benzoate), surfactants (e.g., isostearic acid), cleaning bases (e.g., coconut oil fatty acid PEG-7 glyceryl), colorants (dyes, pigments), fragrances, preservatives, germicides ((antibacterial agents) such as parabens and phenoxyethanol), thickeners (e.g., carboxyvinyl polymers), antioxidants, metal sequestering agents, refreshing agents, deodorants, moisturizers (e.g., glycerin and pentylene glycol), ultraviolet absorbing agents (e.g., 2-ethylhexyl paramethoxycinnamate and octocrylene), ultraviolet scattering agents, vitamins, plant extracts, skin astringents (e.g., ethanol), anti-inflammatory agents (anti-inflammatory agents), skin whitening agents, cell activators, vasodilators, blood circulation promoters, and skin function enhancers.

[0097] The composition of the present invention can be used as an external composition to be applied or sprayed onto the skin. Specifically, the composition of the present invention can be used as an external preparation (dermatological preparation) such as a cosmetic, an external medicine, or an external quasi-drug.

[0098] The form of the composition of the present invention is not particularly limited as long as it can be applied to the skin, and examples thereof include paste, mousse, gel, liquid, emulsion, suspension, cream, ointment, solid, sheet, aerosol, spray, and liniment. In particular, examples of the composition as a cosmetic product include lotion; emulsion such as emollient emulsion, milky lotion, nourishing emulsion, and cleansing emulsion; cream such as emollient cream, massage cream, cleansing cream, and makeup cream; and lip cream. EXAMPLES

[0099] The present invention will be described below with reference to test examples and formulation examples, but the present invention is not limited to these.

[0100] Test Example 1 The skin emulsion compositions of Examples 1 to 6 and Comparative Examples 1 to 3 were prepared by mixing the various components according to the formulation shown in Table 1. Specifically, components 1 to 6, 8, and 9 in the table were mixed while adjusting the pH with component 7, and then mixed uniformly to obtain a gel. Component 10 was mixed uniformly with the obtained gel to form an emulsification. The viscosity and pH of the resulting emulsion composition were measured, and its stability was confirmed by a centrifugation method and a 60°C accelerated test. The pH was measured at room temperature of 25° C. using a pH meter F-52 (manufactured by Horiba, Ltd.). The viscosity was measured using a Brookfield viscometer. Specifically, the viscosity was measured at room temperature (25°C) using a BM type viscometer (Tokyo Keiki Co., Ltd.), rotor No. 3, 12 rpm, and 60 seconds. The unit is mPa·s. The stability was measured using a centrifuge. Specifically, the samples were centrifuged using a himac SCT5BA centrifuge (Hitachi Co., Ltd.) at 2000 rpm for 60 seconds, and the degree of separation was evaluated visually (×: completely separated, ◎: no change).

[0101] [Table 1]

[0102] As shown in Table 1, the emulsion stability of Comparative Examples 1 to 3, which contained a carboxyvinyl polymer, was poor. In contrast, Examples 1 to 6, which contained cross-linked sodium polyacrylate or (PEG-240 / decyltetradeceth-20 / HDI) copolymer, each of which is a water-soluble polymer, showed good emulsion stability.

[0103] Test Example 2 The skin emulsion compositions of Examples 7 to 9 and Comparative Example 4 were prepared by mixing the various components according to the formulation shown in Table 2. Specifically, components 1 to 3 and 8 in the table were mixed while adjusting the pH with components 4 to 7, and then mixed uniformly to obtain a gel. Component 9 was mixed uniformly into the obtained gel to emulsify it. The pH and emulsion stability were measured in the same manner as in Test 1. In addition, the obtained emulsion composition was allowed to stand in a thermostatic chamber at 60° C., and the color and aroma were evaluated by sensory evaluation after two weeks.

[0104] [Table 2]

[0105] As shown in Table 2, the emulsion stability of Comparative Example 4, which contained potassium hydroxide, an inorganic alkali, was poor, and slight discoloration and significant odor were observed. In contrast, Examples 7 to 9, which contained the organic alkali tromethamine, aminomethylpropanediol, or arginine, respectively, showed good emulsion stability, with discoloration results equal to or better than those of Comparative Example 4, and with odor changes better than those of Comparative Example 4.

[0106] Test Example 3-1 The components were mixed according to the formulation shown in Table 3-1 to prepare emulsion compositions for skin in Examples 10 to 13 and Comparative Examples 5 to 6. Specifically, components 1 to 3 and 5 to 7 in the table were mixed while adjusting the pH with component 4, and mixed uniformly to obtain a gel. Components 8 to 12 were mixed with the obtained gel and emulsified.

[0107] A sensory evaluation was carried out by four panelists for Examples 10 to 13 and Comparative Examples 5 to 6. With regard to the feel when used, the thicker the better, the richer the flavor, the less sticky the better, and the fresher the better. <Sensory evaluation score> The same amount of the test composition (0.1 g) was spread with a constant force on the inside of the forearm, and the thickness, richness, non-stickiness, and freshness were evaluated as follows, with Comparative Example 5 being set at 3 points, and the average score of the four panelists was calculated. 5: Significantly improved 4: Improved 3: No difference 2: It got worse 1: Significantly worsened

[0108] The sum of the average scores for thickness, richness, non-stickiness, and freshness was calculated as a total score, and the overall feel in use was evaluated based on this total score as follows: <Overall rating> ◎: Total score of 17 or more ⇒ Usability has been improved 〇: Total score between 13 and 17 ⇒ Usability has improved slightly △: Total score between 10 and 13 ⇒ No improvement in usability was observed ×: Total score less than 10 ⇒ Usability is deteriorating

[0109] [Table 3-1]

[0110] As shown in Table 3-1, Examples 10 to 13, which contain the non-crystalline high melting point oils caprylic / capric / myristic / stearic triglyceride, Theobroma grandiflorum seed butter, or di(octyldodecyl / phytosteryl / behenyl) lauroyl glutamate, showed improved usability compared to Comparative Example 5, which did not contain a non-crystalline high melting point oil. In Comparative Example 6, in which cetanol, a crystalline high melting point oil, was blended, a homogeneous composition was not obtained.

[0111] Test Example 3-2 The components were mixed according to the composition shown in Table 3-2 to prepare emulsion compositions for skin of Comparative Example 7 and Examples 14 to 15. The pH and viscosity of the obtained emulsion compositions for skin were measured in the same manner as in Test Example 1, and the feel during use was evaluated in the same manner as in Test Example 3-1.

[0112] [Table 3-2]

[0113] As shown in Table 3-2, Examples 14 to 15, which contain inulin stearate or dextrin myristate, respectively, as a gelling agent for oily components, showed an improved feel when used compared to Comparative Example 7, which did not contain a gelling agent for oily components.

[0114] Test Example 3-3 The components were mixed according to the composition shown in Table 3-3 to prepare emulsion compositions for skin of Comparative Example 8 and Examples 16 to 17. The pH and viscosity of the obtained emulsion compositions for skin were measured in the same manner as in Test Example 1, and the feel during use was evaluated in the same manner as in Test Example 3-1.

[0115] [Table 3-3]

[0116] As shown in Table 3-3, Examples 16-17, which contained the silicone feel modifiers aminopropyl dimethicone and stearyl dimethicone, respectively, showed improved feel when used compared to Comparative Example 8, which did not contain a silicone feel modifier.

[0117] Formulation examples of oil-in-water emulsion cosmetics All blend amounts are expressed as % by weight of the total product.

[0118] TIFF2025074109000006.tif103136

[0119] TIFF2025074109000007.tif90133

[0120] TIFF2025074109000008.tif108136

[0121] TIFF2025074109000009.tif77140

Claims

1. An O / W type emulsion composition comprising component (A), component (B), component (E), and component (F), and also containing component (C) and / or component (D), and having a viscosity of less than 10,000 mPa·s: Component (A): adenosine phosphate and / or its salt; Component (B): acrylic acid / alkyl methacrylate copolymer; Component (C): a water-soluble polymer selected from a swelling type thickener, an associative type thickener, a polysaccharide and its derivative, and a mixture thereof; Component (D): an organic alkali pH adjuster; Component (E): oil; Component (F): Water.

2. 2. The composition according to claim 1, wherein component (B) is an acrylic acid / alkyl methacrylate copolymer having a molecular weight of 100,000 to 5,000,000.

3. Component (C) is a swelling type thickener selected from sodium polyacrylate, ammonium polyacrylate, ammonium polyacrylate, acrylamide / sodium acrylate copolymer, vinylpyrrolidone / 2-acrylamido-2-methylpropanesulfonic acid copolymer, a mixture of polyacrylic acid amide and sodium polyacrylate, sodium acrylate / 2-acrylamido-2-methylpropanesulfonic acid copolymer, hydroxyethyl acrylate / 2-acrylamido-2-methylpropanesulfonic acid copolymer, and mixtures thereof; urethane associative thickeners selected from PEG-240 / Decyltetradeceth-20 / HDI copolymer, PEG-150 / Stearyl alcohol / SMDI copolymer, PEG-150 / Decyl alcohol / SMDI copolymer, Polyurethane-59, and mixtures thereof; and The composition according to claim 1 or 2, wherein the water-soluble polymer is selected from the mixture thereof.

4. The composition of any one of claims 1 to 3, wherein component (D) is a pH adjuster which is an organic alkali selected from tromethamine, aminomethylpropanediol, aminomethylpropanol, arginine, and mixtures thereof.

5. The composition according to any one of claims 1 to 4, which contains a component (C) and has a component (C) / component (A) (weight ratio) of 0.01 to 30.

6. The composition according to any one of claims 1 to 5, which contains a component (C) and has a weight ratio of component (C) / (component (A)+component (B)) of 0.005 to 20.

7. The composition according to any one of claims 1 to 6, which contains a component (C) and has a component (C) / component (B) (weight ratio) of 0.05 to 60.

8. The composition according to any one of claims 1 to 7, having a pH of from 5.5 to 7.

5.

9. Component (A): adenosine phosphate and / or its salt; Component (B): (acrylates / C10-30 alkyl acrylate) crosspolymer; Component (C): Crosslinked sodium polyacrylate and / or (PEG-240 / Decyltetradeceth-20 / HDI) copolymer; Component (E): oil; and Component (F): water, The composition according to any one of claims 1 to 8, comprising:

10. Component (A): adenosine phosphate and / or its salt; Component (B): (Acrylates / C10-30 alkyl acrylate) crosspolymer; Component (D): tromethamine and / or arginine; Component (E): oil; and Component (F): water, The composition according to any one of claims 1 to 9, having a viscosity of 1,500 to 10,000 mPa·s and a pH of 6 to 7.

11. Contains 0.001 to 10% by weight of component (A), Contains 0.05 to 2% by weight of component (B); Contains 0.1 to 50% by weight of component (E); The composition according to any one of claims 1 to 10.

12. The composition according to any one of claims 1 to 11, comprising 0.01 to 10% by weight of component (C).

13. Component (A): adenosine phosphate and / or a salt thereof 0.4 to 3.5% by weight; Component (B): (acrylates / alkyl acrylate (C10-30)) crosspolymer 0.2 to 0.4% by weight; Component (C): Crosslinked sodium polyacrylate and / or (PEG-240 / Decyltetradeceth-20 / HDI) copolymer 0.04-0.8% by weight; Component (E): oil 5 to 8% by weight; and Component (F): water, The composition according to any one of claims 1 to 12, comprising:

14. Component (A): adenosine phosphate and / or a salt thereof 0.4 to 3.5% by weight; Component (B): (acrylates / alkyl acrylate (C10-30)) crosspolymer 0.2-0.4 wt.%; Component (D): tromethamine, aminomethylpropanediol, and / or arginine; Component (E): oil 5 to 8% by weight; and Component (F): water, The composition according to any one of claims 1 to 13, having a viscosity of 1,500 to 10,000 mPa·s and a pH of 6 to 7.

15. Does not contain an inorganic alkaline pH adjuster, or The composition according to any one of claims 1 to 14, which contains an inorganic alkaline pH adjuster and has a weight ratio of inorganic alkaline pH adjuster / component (D) of 0.1 or less.

16. Component (E) is A non-crystalline high melting point oil having a melting point of 30° C. or higher selected from the group consisting of non-crystalline triglycerides having a melting point of 30° C. or higher, non-crystalline fatty acid sterol esters having a melting point of 30° C. or higher, petrolatum, and mixtures thereof; a gelling agent for oily components selected from fatty acid inulin, fatty acid dextrin, polyglycerin, dibutyl ethylhexanoyl glutamide, dibutyl lauroyl glutamide, sodium dilauroyl glutamate lysine, (vinyl dimethicone / methicone silsesquioxane) crosspolymer, PEG / PPG-19 / 19 dimethicone, and mixtures thereof; a silicone feel modifier selected from amino modified silicones, silicone waxes, polyether modified silicones, highly polymerized dimethicones, silicone waxes, silicone emulsions, silicone powders, and mixtures thereof; and The mixture The composition according to any one of claims 1 to 15, comprising a component (G) selected from the following, and component (G) is contained in component (E) in an amount of 0.1 to 50% by weight.

17. The composition according to any one of claims 1 to 16, comprising 0.1 to 5 wt% of component (G).

18. Component (H): Water-soluble moisturizer The composition according to any one of claims 1 to 17, further comprising:

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