Oil-in-water emulsion cosmetic

Abstract

To provide cosmetics that offer both effective improvement of skin blemishes and wrinkles and a pleasant user experience. [Solution] (A) Glycine derivative or salt thereof, (B) Nicotinic acid or derivative thereof, (C) an alkyl-modified carboxyvinyl polymer, (D) an oil, and (E) water, comprising an oil-in-water emulsion cosmetic. This cosmetic contains 0.3 to 5% by mass of component (A) based on the total amount of the cosmetic.

Description

[Technical Field]

[0001] This invention relates to an oil-in-water emulsion cosmetic. [Background technology]

[0002] In cosmetics, the feel of the product is an important characteristic, and there is much research being done to improve it. It is known that incorporating alkyl-modified carboxyvinyl polymer as an emulsifier can provide a refreshing feel and suppress stickiness after application (Patent Document 1).

[0003] On the other hand, niacinamide is known as a drug that can improve skin blemishes and wrinkles. Furthermore, Reference 2 discloses the combination of anionic polymers in topical skin preparations containing niacinamide, and that alkyl-modified carboxyvinyl polymers can be used as such anionic polymers.

[0004] However, our own research has shown that when niacinamide is combined with alkyl-modified carboxyvinyl polymer, the refreshing feeling during use may be insufficient, and the usability-improving effect of alkyl-modified carboxyvinyl polymer may not be fully realized. For this reason, there has been a desire to further improve the usability of cosmetics combining niacinamide and alkyl-modified carboxyvinyl polymer. [Prior art documents] [Patent Documents]

[0005] [Patent Document 1] International Publication No. 2023 / 047979 Specification [Patent Document 2] International Publication No. 2021 / 075413 [Overview of the Initiative]

[0006] The present invention provides a cosmetic composition that fully exhibits the effect of niacinamide in improving skin blemishes and wrinkles, and the refreshing feel of alkyl-modified carboxyvinyl polymer.

[0007] The present invention provides the following: [1] (A) The following formula (1): [ka] (In the formula, R 1 and R 2 Each of these is independently a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, an aralkyl group, an aminomethylcarbonyl group, an amidino group, an alkylcarbonyl group, an alkenylcarbonyl group, an arylcarbonyl group, or an aralkylcarbonyl group. R 3 These are a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, or an aralkyl group. However, R 1 , R 2 , and R 3 (They cannot simultaneously become hydrogen atoms.) A glycine derivative or salt thereof represented by (B) Nicotinic acid or its derivatives, (C) Alkyl-modified carboxyvinyl polymer, (D) Oils and (E)Water An oil-in-water emulsion cosmetic comprising, An oil-in-water emulsion cosmetic in which the amount of component (A) is blended is 0.3 to 5% by mass of the total amount of the cosmetic. [2] The oil-in-water emulsion cosmetic composition according to [1], wherein the aforementioned component (A) comprises glycylglycine or a salt thereof. [3] The oil-in-water emulsion cosmetic composition according to [1] or [2], wherein the (B) component comprises nicotinamide. [4] The water-in-oil type emulsified cosmetic according to any one of [1] to [3], wherein the blending amount of the component (B) is 3 to 10% by mass based on the total amount of the cosmetic. [5] The water-in-oil type emulsified cosmetic according to any one of [1] to [4], wherein the component (C) contains an (acrylates / acrylic acid alkyl (C10-30)) cross-polymer. [6] The water-in-oil type emulsified cosmetic according to any one of [1] to [5], wherein the component (D) contains silicone oil. [7] The water-in-oil type emulsified cosmetic according to any one of [1] to [6], further containing (F) carboxyvinyl polymer.

[0008] According to the present invention, there is provided a cosmetic that achieves both the effects of niacinamide and the effects of an alkyl-modified carboxyvinyl polymer. More specifically, according to the present invention, a cosmetic excellent in improving skin spots and wrinkles and in freshness during use can be realized. DETAILED DESCRIPTION OF THE INVENTION

[0009] The water-in-oil type emulsified cosmetic according to the present invention (hereinafter sometimes simply referred to as "cosmetic") comprises (A) a glycine derivative or a salt thereof, (B) nicotinic acid or a derivative thereof, (C) an alkyl-modified carboxyvinyl polymer, (D) an oil component, and (E) water and comprises the following. Each of these components and further components that can be blended will be described below.

[0010] (A) Glycine derivative or a salt thereof The cosmetic according to the present invention comprises a glycine derivative or a salt thereof (hereinafter sometimes referred to as component (A)). The glycine derivative is represented by the formula (1). [Chemical formula] (In the formula, R 1 and R 2is, independently of each other, a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, an aralkyl group, an aminomethylcarbonyl group, an amidino group, an alkylcarbonyl group, an alkenylcarbonyl group, an arylcarbonyl group, or an aralkylcarbonyl group, R 3 is a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, or an aralkyl group. However, R 1 R 2 and R 3 will not simultaneously be hydrogen atoms.

[0011] The component (A) may be a salt of a glycine derivative represented by the formula (1). The type of the salt is not particularly limited as long as it is a pharmacologically acceptable salt, and examples thereof include hydrochloride, sulfate, phosphate, hydrobromide, sodium salt, potassium salt, magnesium salt, calcium salt, magnesium salt, ammonium salt, etc. Examples of the organic salt include acetate, lactate, maleate, fumarate, tartrate, methanesulfonate, p-toluenesulfonate, triethanolamine salt, amino acid salt, etc. The component (A) preferably contains glycylglycine.

[0012] One or more kinds of the component (A) can be blended. The blending amount of the component (A) is 0.3 to 5% by mass, preferably 0.5 to 3% by mass, and more preferably 1 to 2% by mass based on the total mass of the cosmetic.

[0013] (B) Nicotinic acid or its derivative The cosmetic according to the present invention comprises nicotinic acid or its derivative (hereinafter sometimes referred to as the component (B)). Nicotinic acid derivatives are well known as those giving a whitening effect in cosmetics, and in the present invention, its effect is sufficiently exhibited and the effect of improving skin spots and wrinkles is high.

[0014] (B) The component can be arbitrarily selected and used from those used in cosmetic applications and pharmaceutical applications, for example Nicotinic acid, Nicotinamide, Benzyl nicotinate, Nicotinate tocopherol, and β-butoxy nicotinate It is preferable that the substance be selected from the group consisting of the above, and it is particularly preferable that the substance be nicotinamide.

[0015] In the cosmetic composition according to the present invention, the amount of component (B) can be arbitrarily selected depending on the purpose, but it is preferably 3 to 10% by mass, and more preferably 4 to 8% by mass, based on the total mass of the cosmetic composition. Increasing the amount tends to make the effect of component (B) stronger, but even if the amount exceeds a certain level, it becomes difficult to obtain an effect proportional to the amount, so it is preferable to keep it within the above range.

[0016] (C) Alkyl-modified carboxyvinyl polymer, The cosmetic composition according to the present invention comprises (C) an alkyl-modified carboxyvinyl polymer (hereinafter sometimes referred to as component (C)). Component (C) is an alkyl acrylate methacrylate copolymer, which is a polymer in which at least a portion of the carboxyl groups of a polymer having acrylic acid or methacrylic acid as the main chain are esterified with an alkyl group. The alkyl group linked by the ester bond may be linear or branched, and its carbon number is preferably 10 to 30. Component (C) is preferably a crosspolymer in which polymers or copolymers containing alkyl acrylate or alkyl methacrylate as polymerization units are crosslinked with each other. Component (B) preferably includes, for example, acrylates / alkyl acrylate (C10-30) crosspolymer.

[0017] (C) Component may be included in one or more combinations. The amount of component (C) is preferably 0.005 to 1.5% by mass, and more preferably 0.01 to 0.5% by mass, relative to the total amount of the cosmetic.

[0018] (D) Oil The cosmetic composition according to the present invention comprises (D) an oil component. Examples of component (D) include silicone oil, hydrocarbon oil, higher fatty acid, higher alcohol, ester oil, liquid oil, solid oil, semi-solid oil, etc., and is preferably silicone oil or hydrocarbon oil, and more preferably silicone oil.

[0019] Examples of silicone oils include linear polysiloxanes (e.g., dimethicone, diphenylsiloxyphenyl trimethicone, diphenylpolysiloxane, etc.), cyclic polysiloxanes (e.g., octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, dodecamethylcyclohexasiloxane, etc.), silicone resins forming a three-dimensional network structure, silicone rubber, various modified polysiloxanes (amino-modified polysiloxane, polyether-modified polysiloxane, alkyl-modified polysiloxane, fluorine-modified polysiloxane, etc.), acrylic silicones, etc., with linear polysiloxane being preferred.

[0020] Examples of hydrocarbon oils include isododecane, isohexadecane, isoparaffin, mineral oil (liquid paraffin), ozokerite, squalane, pristane, paraffin, ceresin, squalene, petrolatum, microcrystalline wax, and hydrogenated polydecene.

[0021] Examples of high-grade fatty acids include lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, undecylenic acid, tallic acid, isostearic acid, linoleic acid, linolenic acid, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

[0022] Examples of higher alcohols include straight-chain alcohols (e.g., lauryl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, myristyl alcohol, oleyl alcohol, cetostearyl alcohol, etc.) and branched-chain alcohols (e.g., lanolin alcohol, cholesterol, phytosterol, hexyldodecanol, isostearyl alcohol, octyldodecanol, etc.).

[0023] Examples of ester oils include octyl octanoate, nonyl nonanoate, cetyl octanoate, isopropyl myristate, octyldodecyl myristate, isopropyl palmitate, ethylhexyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, decyl oleate, hexyldecyl dimethyloctanoate, cetyl lactate, myristyl lactate, lanolin acetate, isocetyl stearate, isocetyl isostearate, 12-hydroxys Cholesteryl thearate, ethylene glycol di-2-ethylhexanoate, dipentaerythritol fatty acid ester, N-alkyl glycol monoisostearate, neopentyl glycol dicaprate, tripropylene glycol pivalate, diisostearyl malate, glyceryl di-2-heptylundecanoate, glyceryl diisostearate, trimethylolpropane tri-2-ethylhexanoate, trimethylolpropane triisostearate, tetra-2 - Pentaerythritol ethylhexanoate, glycerin tri-2-ethylhexanoate, glycerin trioctanoate, glycerin triisopalmitate, trimethylolpropane triisostearate, cetyl 2-ethylhexanoate-2-ethylhexyl palmitate, glycerin trimyristate, glyceride tri-2-heptylundecanoate, methyl castor oil fatty acid ester, oleyl oleate, acetoglyceride, 2-heptylundecyl palmitate, Examples include diisobutyl adipate, 2-octyldodecyl N-lauroyl-L-glutamic acid, di-2-heptylundecyl adipate, ethyl laurate, di-2-ethylhexyl sebacate, 2-hexyldecyl myristate, 2-hexyldecyl palmitate, 2-hexyldecyl adipate, diisopropyl sebacate, 2-ethylhexyl succinate, triethyl citrate, cetyl ethylhexanoate, and macadamia nut fatty acid phytosteryl.

[0024] Examples of liquid oils include avocado oil, camellia oil, macadamia nut oil, corn oil, olive oil, rapeseed oil, sesame oil, peach kernel oil, wheat germ oil, sasanqua oil, castor oil, linseed oil, safflower oil, cottonseed oil, elm oil, soybean oil, peanut oil, tea seed oil, kaya oil, rice bran oil, cinnamon oil, Japanese tuni oil, jojoba oil, germ oil, and triglycerin. Examples of solid oils include cocoa butter, coconut oil, hydrogenated coconut oil, palm oil, palm kernel oil, hydrogenated palm oil, Japanese wax kernel oil, hydrogenated oil, Japanese wax, and hydrogenated castor oil. Examples of semi-solid oils include shea butter, partially hydrogenated coconut oil, and partially hydrogenated jojoba oil.

[0025] (C) Component may be blended as one or more types. The amount of component (C) blended is preferably 30% by mass or less, more preferably 0.1 to 20% by mass, even more preferably 0.5 to 15% by mass, and particularly preferably 1.0 to 8.5% by mass, based on the total amount of the cosmetic.

[0026] (E)Water The cosmetic composition according to the present invention comprises water (hereinafter sometimes referred to as component (E)). As the water, water used for cosmetics, quasi-drugs, etc., can be used, for example, purified water, ion-exchanged water, tap water, etc. The amount of water added is preferably 20 to 95% by mass, and more preferably 60 to 90% by mass, relative to the total amount of the cosmetic composition according to the present invention.

[0027] (F) Carboxyvinyl polymer The cosmetic composition according to the present invention contains the above components (A) to (E) as essential components, but may further contain a carboxyvinyl polymer (hereinafter sometimes referred to as component (F)). This carboxyvinyl polymer is a polymer of acrylic acid with acrylic acid as the main chain and crosslinked with pentaerythristyl ariether, sucrose ariether, or propylene ariether, and is different from component (C) and is not alkyl-modified. This component (F) functions as a thickener to adjust the viscosity of the cosmetic composition.

[0028] (F) One or more types of component (F) may be included. The amount of component (F) is preferably 0.001 to 5% by mass or less, and more preferably 0.01 to 3% by mass, relative to the total amount of the cosmetic.

[0029] (G) Optional component In addition to the above-mentioned components, the cosmetic composition according to the present invention may contain any other components commonly used in cosmetics and pharmaceuticals. Examples of optional components include those listed below, and one or more of these may be included as long as they achieve the effects of the present invention.

[0030] As an ingredient to stabilize the dispersion state of the cosmetic composition according to the present invention, surfactants, particularly nonionic surfactants, can be incorporated. The surfactant is not particularly limited as long as it is an surfactant commonly used in topical preparations such as cosmetics and quasi-drugs, and especially a nonionic surfactant, but for example, fatty acid polyoxyalkylene glyceryl such as PEG-60 glyceryl isostearate; polyoxyethylene hydrogenated castor oil such as PEG-40 hydrogenated castor oil, PEG-60 hydrogenated castor oil, PEG-100 hydrogenated castor oil; polyoxyethylene methylpolysiloxyethyl dimethicone such as PEG-3 dimethicone, PEG-9 dimethicone, PEG-10 dimethicone, PEG-12 dimethicone, PEG-9 polydimethylsiloxyethyl dimethicone Copolymers; polyglycerin fatty acid esters such as polyglyceryl-2 diisostearate and polyglyceryl-2 triisostearate; monoglycerin fatty acid esters such as glyceryl stearate and glyceryl oleate; polyoxyethylene sorbitan fatty acid esters such as polyoxyethylene sorbitan monooleate and polyoxyethylene sorbitan monostearate; sorbitan fatty acid esters such as sorbitan sesquioleate, sorbitan sesquiisostearate, sorbitan isostearate, and sorbitan palmitate can be used.

[0031] Alkylene oxide derivatives can be used to improve the user experience. Specifically, alkylene oxide derivatives represented by formula (2) can be used. R 4O-[(AO)a(EO)b]-R 5 (2) During the ceremony, R 4 and R 5 Each of these is an alkyl group having 1 to 4 carbon atoms, such as a methyl group, ethyl group, n-propyl group, isopropyl group, n-butyl group, sec-butyl group, tert-butyl group, etc., and preferably a methyl group or an ethyl group. AO is an oxyalkylene group having 3 or 4 carbon atoms, such as an oxypropylene group, an oxybutylene group, an oxyisobutylene group, an oxytrimethylene group, an oxytetramethine group, and so on, with an oxypropylene group or an oxybutylene group being preferred. EO stands for oxyethylene group. a and b are the average number of moles added of AO and EO, respectively, satisfying 1 ≤ a ≤ 70, preferably 2 ≤ a ≤ 70, and 1 ≤ b ≤ 70, preferably 2 ≤ b ≤ 70. a + b is preferably between 8 and 100.

[0032] The order in which AO and EO are added is not particularly limited. AO and EO may be added in a block pattern or randomly, but randomly is preferred. The block pattern may be not limited to two-tiered blocks, but may also consist of three or more tiered blocks.

[0033] Specific examples of alkylene oxide derivatives include, PEG / PPG-10 / 10 dimethyl ether, PEG / PPG-9 / 2 dimethyl ether, PEG / PPG-14 / 7 Dimethyl Ether, PEG / PPG-17 / 4 Dimethyl Ether, PEG / PPG-6 / 14 Dimethyl Ether, PEG / PPG-15 / 5 Dimethyl Ether, PEG / PPG-25 / 25 dimethyl ether, PEG / PBG-9 / 2 Dimethyl Ether, PEG / PBG-14 / 7 Dimethyl Ether, PEG / PPG-10 / 10 diethyl ether, PEG / PPG-10 / 10 dipropyl ether, PEG / PPG-10 / 10 dibutyl ether, Examples include PEG / PPG-36 / 41 polydimethyl ether.

[0034] Examples of humectants include polyethylene glycol, propylene glycol, dipropylene glycol (DPG), glycerin, 1,3-butylene glycol (BG), erythritol, xylitol, sorbitol, maltitol, chondroitin sulfate, hyaluronic acid, mucoitin sulfate, carotenoid acid, atelocollagen, cholesteryl-12-hydroxystearate, sodium lactate, bile salts, dl-pyrrolidone carboxylate, short-chain soluble collagen, Rosa rugosa extract, Achillea millefolium extract, and Melilotus extract.

[0035] Examples of lower alcohols include ethanol, 1-propanol, 2-propanol, isobutyl alcohol, and t-butyl alcohol.

[0036] As a thickening agent, one can be selected from those generally known as thickening agents, excluding component (F) mentioned above. Examples include gum arabic, carrageenan, karaya gum, tragacanth gum, carob gum, quince seed (marmelo), casein, dextrin, gelatin, sodium pectinate, sodium araginate, methylcellulose, ethylcellulose, CMC, hydroxyethylcellulose, hydroxypropylcellulose, PVA, PVM, PVP, sodium polyacrylate, locust bean gum, guar gum, tamarind gum, dialkyldimethylammonium sulfate cellulose, xanthan gum, aluminum magnesium silicate, bentonite, hectorite, aluminum magnesium silicate (bee gum), laponite, anhydrous silicic acid, etc.

[0037] Examples of metal ion chelating agents include 1-hydroxyethane-1,1-diphosphonic acid, tetrasodium 1-hydroxyethane-1,1-diphosphonic acid, disodium edetate, trisodium edetate, tetrasodium edetate, sodium citrate, sodium polyphosphate, sodium metaphosphate, gluconic acid, phosphoric acid, citric acid, succinic acid, edetate, and trisodium ethylenediaminehydroxyethyl triacetate.

[0038] Examples of neutralizing agents include 2-amino-2-methyl-1-propanol, 2-amino-2-methyl-1,3-propanediol, potassium hydroxide, sodium hydroxide, triethanolamine, and sodium carbonate.

[0039] Examples of pH adjusting agents include buffering agents such as lactate-sodium lactate, citrate-sodium citrate, and succinate-sodium succinate. Examples of antioxidants include dibutylhydroxytoluene, butylhydroxyanisole, sodium pyrosulfite, and gallic acid esters. Examples of preservatives include para-hydroxybenzoic acid esters such as methylparaben, ethylparaben, and butylparaben, as well as benzoic acid, salicylic acid, sorbic acid, parachlormethacresol, hexachlorophene, benzalkonium chloride, chlorhexidine chloride, trichlorocarbanilide, photosensitizer, and phenoxyethanol.

[0040] Examples of drugs include ascorbic acid (vitamin C), tranexamic acid, kojic acid, ellagic acid, arbutin, alkoxysalicylic acid, glycyrrhizic acid, tocopherol, retinol, and salts or derivatives thereof (e.g., sodium L-ascorbate, magnesium L-ascorbate ester salt, L-ascorbic acid glucoside, 2-O-ethyl-L-ascorbic acid, 3-O-ethyl-L-ascorbic acid, sodium 4-methoxysalicylate salt, potassium 4-methoxysalicylate salt, dipotassium glycyrrhizate, stearyl glycyrrhetinate, tocopherol acetate, retinol acetate, retinol palmitate, etc.), caffeine, tannins, verapamil, and so on. Examples include derivatives of licorice, glabridin, hot water extract of fire vine fruit, various herbal medicines, hydrolyzed silk, hydrolyzed conchiolin, tea extract, tormentilla root extract, angelica leaf / stem extract, aloe vera leaf extract, cherry leaf extract, angelica root extract, shiitake mushroom peel extract, iris root extract, spiny cypress / shrimp / kelp / green laver / unripe seaweed extract, cattail spike extract, Isodon leaf / stem extract, camellia seed extract, kelp / unripe seaweed extract, Bupleurum falcatum root extract, watercress leaf / stem extract, cassia bark extract, rosemary leaf oil, lavender oil, glutamic acid, trimethylglycine, chlorphenesin, menthoxypropanediol, etc.

[0041] In addition, UV absorbers, powdered ingredients, fragrances, etc., can be added as appropriate.

[0042] Examples of cosmetics according to the present invention include skincare cosmetics (e.g., lotions, emulsions, creams, serums, packs, masks, etc.), makeup cosmetics (e.g., foundations, makeup bases, etc.), skin cleansing products (e.g., facial cleansers, makeup removers, etc.), sunscreen cosmetics, ointments, etc. However, these forms are merely examples, and the cosmetics according to the present invention are not limited to these forms.

[0043] The cosmetic composition of the present invention is not particularly limited by the emulsification method and can be manufactured according to conventional methods. The average emulsion particle size is not particularly limited, but is preferably 0.1 to 30 μm, and more preferably 0.5 to 20 μm. The average emulsion particle size can be measured using a microscope. The viscosity is not particularly limited, but is preferably 100 to 100,000 mPa·s, more preferably 500 to 30,000 mPa·s, and particularly preferably 1,000 to 15,000 mPa·s. The viscosity can be measured at 30°C using a B-type viscometer. [Examples]

[0044] The present invention will be specifically described based on the following examples, but the present invention is not limited to these examples. Unless otherwise specified, the amounts are expressed as mass % of the total amount.

[0045] [Examples 1-3, Comparative Examples 1-3] Cosmetic compositions for each example and each comparative example were prepared using the formulations shown in Table 1.

[0046] Furthermore, the performance of these cosmetics was evaluated on a three-point scale from A (excellent) to C (insufficient) based on the level of freshness felt during use.

[0047] [Table 1]

Claims

1. (A) The following formula (1): 【Chemistry 1】 (In the formula, R １ and R ２ Each of these is independently a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, an aralkyl group, an aminomethylcarbonyl group, an amidino group, an alkylcarbonyl group, an alkenylcarbonyl group, an arylcarbonyl group, or an aralkylcarbonyl group. R ３ These are a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, or an aralkyl group. However, R １ , R ２ , and R ３ (They cannot simultaneously become hydrogen atoms.) A glycine derivative or salt thereof represented by (B) Nicotinic acid or its derivatives, (C) Alkyl-modified carboxyvinyl polymer, (D) Oils, and (E) Water An oil-in-water emulsion cosmetic comprising, An oil-in-water emulsion cosmetic in which the amount of component (A) is blended is 0.3 to 5% by mass relative to the total amount of the cosmetic.

2. The oil-in-water emulsion cosmetic composition according to claim 1, wherein component (A) comprises glycylglycine or a salt thereof.

3. The oil-in-water emulsion cosmetic composition according to claim 1, wherein the (B) component comprises nicotinamide.

4. The oil-in-water emulsion cosmetic according to claim 1, wherein the amount of component (B) is 3 to 10% by mass relative to the total amount of the cosmetic.

5. The oil-in-water emulsion cosmetic composition according to claim 1, wherein the (C) component comprises (acrylates / alkyl acrylate (C10-30)) crosspolymer.

6. The oil-in-water emulsion cosmetic composition according to claim 1, wherein the (D) component comprises silicone oil.

7. (F) The oil-in-water emulsion cosmetic composition according to claim 1, further comprising a carboxyvinyl polymer.

Images