Skin cleansing spray

Abstract

To provide a skin cleanser composition that is used in an unconventional method.SOLUTION: A spray agent for skin cleansing, which contains (A) a surfactant and (B) an amphiphilic ester and has a pH of 3 to 8, while being contained in a spray container, is capable of exhibiting excellent cleansing power, while being reduced in the skin irritancy of a skin cleanser composition, and is able to provide a novel use that is different from conventional uses in which the skin cleanser composition is foamed before application to the skin, said novel use being direct spraying of the skin cleanser composition onto the skin.SELECTED DRAWING: None

Description

[Technical field]

[0001] The present invention relates to a spray agent for cleansing the skin which is sprayed directly onto the skin. [Background technology]

[0002] As products for cleaning the skin and keeping it clean, various skin cleansing compositions such as face washes, body soaps, shampoos, etc. are provided. In the mechanism by which skin cleansing compositions cleanse the skin, the surfactant adsorbs to dirt, reducing the surface tension between the dirt and water, and, together with the mechanical force due to friction, causes the dirt to float up in the water. In order to make such a cleaning mechanism work effectively, it is necessary to incorporate the surfactant at a critical micelle concentration or higher.

[0003] On the other hand, the current situation is that the cleaning power of surfactants is too strong, which causes skin irritation, resulting in skin troubles such as dry skin. For this reason, various formulations have been proposed that devise combinations and amounts of cleaning ingredients in order to make the action on the skin milder. Among them, since it is recognized that the foam formed during cleaning reduces the friction generated by direct contact between the skin and fingers, it is generally accepted that a formulation that improves foam quality such as foaming power and foam retention is excellent as a formulation that makes the action on the skin milder.

[0004] For this reason, in recent years, various pump foamer-type skin cleansers have been proposed, and they have attracted attention not only for their convenience of easily obtaining good quality foam, but also for their gentleness to the skin. Specifically, Patent Document 1 discloses a liquid skin cleansing agent product comprising a foamer container and a liquid skin cleansing agent composition filled in the foamer container, the liquid skin cleansing agent composition containing (A) 3-10% by mass of a specific fatty acid salt having a linear or branched monovalent hydrocarbon group having 7-21 carbon atoms, (B) a specific copolymer of dimethyldiallylammonium chloride and acrylic acid and / or acrylamide, and (C) a sugar alcohol, and the mass ratio (A) / (B) of the content of the component (A) to the content of the component (B) is 20-250. Patent Document 2 discloses a skin cleansing composition characterized in that the cleansing agent contains (a) 2-9% by mass of fatty acid salt, (b) 0.5-4% by mass of lauryldimethylaminoacetate betaine, and (c) 1-10% by mass of one or more dihydric alcohols, and the sum of the blending amounts (mass%) of the (a) and (b) components (a)+(b) is 3-10% by mass, and the blending amount ratio (b) / (a) is 0.1-0.5, filled in a former container. Patent Document 3 discloses a cleansing composition discharged from a former container, which contains (a) lauryldimethylaminoacetate betaine and (b) 4-15% by mass of a higher fatty acid soap formed from a fatty acid having 5-25 carbon atoms and having a specific composition. [Prior art documents] [Patent documents]

[0005] [Patent Document 1] International Publication No. 2014 / 003114 [Patent Document 2] JP 2016-098182 A [Patent Document 3] International Publication No. 2017 / 081897 Summary of the Invention [Problem to be solved by the invention]

[0006] Pump foamer-type skin cleansing compositions contain a relatively small amount of surfactant, and in this respect, they tend to cause less irritation to the skin than solid or semi-solid skin cleansing compositions. On the other hand, since the pump foamer-type skin cleansing composition is premised on being discharged in a foam state, it is unavoidable from the viewpoint of its composition to contain the minimum amount of surfactant required to exert foaming power.

[0007] In addition, various skin cleansers have been created for the purpose of removing body fluids such as sebum and sweat, dirt, etc., excluding skin cleansers for makeup removal (cleansing), but all of them, without exception, are premised on being foamed before application to the skin, and it is also common knowledge that foaming well before washing is preferable in terms of reducing friction on the skin. Although foam can reduce physical friction by being placed between the skin and the hands, the foam itself is rubbed against the skin, which in itself generates physical friction and is still irritating to the skin. Irritation remains a concern, especially for skin that is sensitive to irritants.

[0008] As such, there is a limit to how much the burden of skin cleansing agents can be reduced by using them in the same way as before. For this reason, it is considered necessary to develop skin cleansing agents that are less irritating to the skin than ever before so that they can be used on sensitive skin.

[0009] Therefore, an object of the present invention is to provide a skin cleansing composition that is used in a manner different from conventional methods. [Means for solving the problem]

[0010] The present inventors came up with the novel idea of ​​directly spraying a skin cleansing composition onto the skin without foaming it beforehand, in order to further reduce skin irritation. They also found that by making an amphiphilic ester coexist with a surfactant and adjusting the pH to 3 to 8, effective cleansing power can be obtained without foaming it beforehand. The present invention was completed through further investigations based on this finding.

[0011] That is, the present invention provides the following aspects. Item 1. A skin cleansing spray containing (A) a surfactant and (B) an amphiphilic ester, having a pH of 3 to 8, and contained in a spray container. Item 2. The skin cleansing spray according to Item 1, wherein the spray container is a pump spray container. Item 3. The skin cleansing spray according to Item 1, wherein the spray container is an aerosol spray container. Item 4. The skin cleansing spray according to any one of Items 1 to 3, wherein the component (B) is selected from the group consisting of dicarboxylate bis(polyoxyalkylene alkyl ether) esters, dicarboxylate dialkoxyalkyl esters, and polyglyceryl-10 (eicosadioate / tetradecanedioate). Item 5. The skin cleansing spray according to any one of Items 1 to 4, wherein the dicarboxylic acid bis(polyoxyalkylene alkyl ether) ester is cyclohexane-1,4-dicarboxylate bisethoxydiglycol. Item 6. The skin cleansing spray according to any one of items 1 to 5, wherein the content of the component (A) is 0.025 to 2% by weight. Item 7. The skin cleansing spray according to any one of Items 1 to 6, which is applied to sensitive skin. Effect of the Invention

[0012] According to the present invention, the skin cleansing composition can exert excellent cleansing power while reducing skin irritation, and therefore, unlike the conventional use in which the skin is foamed before application to the skin, a new use can be provided in which the skin cleansing composition is directly sprayed onto the skin for application. Since cleaning is possible without foaming beforehand, the amount of surfactant blended in the skin cleansing liquid composition can be significantly reduced compared to the amount blended in conventional skin cleansing liquid compositions, which makes it possible to further reduce skin irritation. Therefore, the skin cleansing spray agent can be suitably used for cleaning skin that has become sensitive to irritation. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0013] The skin cleansing spray of the present invention is characterized by containing (A) a surfactant (hereinafter sometimes referred to as component (A)) and (B) an amphiphilic ester (hereinafter sometimes referred to as component (B)), adjusted to a predetermined pH, and contained in a spray container. The skin cleansing spray of the present invention will be described in detail below.

[0014] (A) Surfactant The skin cleansing spray of the present invention contains a surfactant as component (A). The surfactant is not particularly limited, but from the viewpoint of suppressing irritation to the skin, preferred examples include anionic surfactants, nonionic surfactants, amphoteric surfactants, natural surfactants, etc. As the surfactant, one of anionic surfactants, nonionic surfactants, amphoteric surfactants, and natural surfactants may be used alone, or two or more of them may be used in any combination.

[0015] Examples of the anionic surfactant used in the present invention include carboxylic acid type, sulfonic acid type, sulfate type, and phosphate type surfactants.

[0016] Specific examples of carboxylic acid type surfactants include saturated or unsaturated fatty acids having 6 to 22 carbon atoms, such as octanoic acid, decanoic acid, lauric acid, myristic acid, palmitic acid, and stearic acid; and N-acylamino acids having saturated or unsaturated N-acyl groups having 8 to 24 carbon atoms, such as an octanoyl group, a decanoyl group, a lauroyl group, a myristoyl group, a palmitoyl group, and a cocoyl group (carboxylic acid type amino acid anionic surfactants).

[0017] Examples of the carboxylic acid type amino acid anionic surfactant include N-acylamino acids having a saturated or unsaturated N-acyl group having 8 to 24 carbon atoms, such as an octanoyl group, a decanoyl group, a lauroyl group, a myristoyl group, a palmitoyl group, and a cocoyl group. Examples of the N-acylamino acids in the carboxylic acid type amino acid anionic surfactant include N-acylsarcosine, N-acylaspartic acid, N-acylglutamic acid, and N-acyl-N-methyl-β-alanine. More specific examples of the carboxylic acid type amino acid anionic surfactant include N-lauroylsarcosine, cocoylsarcosine, N-lauroylaspartic acid, cocoylaspartic acid, N-lauroylglutamic acid, cocoylglutamic acid, N-lauroyl-N-methyl-β-alanine, and cocoylmethylalanine.

[0018] Specific examples of sulfonic acid type surfactants include esters of fatty acids having 6 to 22 carbon atoms, such as cocoyl isethionic acid, and isethionic acid; alkylsulfonic acids having 6 to 22 carbon atoms, such as hexanesulfonic acid, octanesulfonic acid, decanesulfonic acid, and dodecanesulfonic acid; alkylbenzenesulfonic acids having an alkyl group having 10 to 16 carbon atoms, such as alkylbenzenesulfonic acid; and N-acyl-N-methyltaurines (sulfonic acid type amino acid anionic surfactants) having saturated or unsaturated N-acyl groups having 8 to 24 carbon atoms, such as an octanoyl group, a decanoyl group, a lauroyl group, a myristoyl group, a palmitoyl group, and a cocoyl group.

[0019] Examples of the sulfonic acid type amino acid anionic surfactant include N-acyl-N-methyltaurine having a saturated or unsaturated N-acyl group having 8 to 24 carbon atoms, such as an octanoyl group, a decanoyl group, a lauroyl group, a myristoyl group, a palmitoyl group, a cocoyl group, etc. More specific examples of the sulfonic acid type amino acid anionic surfactant include N-myristoyl-N-methyltaurine, N-lauroyl-N-methyltaurine, and cocoyl methyltaurine.

[0020] Specific examples of sulfate ester surfactants include esters of saturated or unsaturated fatty acids having 10 to 22 carbon atoms, such as lauryl sulfate and myristyl sulfate, and sulfate.Specific examples of phosphate ester surfactants include esters of saturated or unsaturated fatty acids having 8 to 24 carbon atoms, such as lauryl phosphoric acid, and phosphoric acid.

[0021] These anionic surfactants may be in the form of a salt, for example, an alkali metal salt such as a sodium salt or a potassium salt; a triethanolamine (TEA) salt; an ammonium salt, or the like.

[0022] Among these anionic surfactants, from the viewpoint of obtaining better skin irritation reduction properties and cleaning power, preferably carboxylic acid type surfactants and sulfonic acid type surfactants are mentioned, and more preferably carboxylic acid type amino acid anionic surfactants and sulfonic acid type amino acid anionic surfactants are mentioned. Carboxylic acid type amino acid anionic surfactants and sulfonic acid type amino acid anionic surfactants are preferably used from the viewpoint of suppressing the feeling of tension due to insufficient moisture retention, or from the viewpoint of suppressing the feeling of tension due to insufficient moisture retention and cleaning power, when the pH of the skin cleaning spray of the present invention is, for example, 3 to 6. More specifically, carboxylic acid type amino acid anionic surfactants and sulfonic acid type amino acid anionic surfactants are preferably used from the viewpoint of suppressing the feeling of tension due to insufficient moisture retention, when the pH of the skin cleaning spray of the present invention is, for example, 3 to 4, and are preferably used from the viewpoint of suppressing the feeling of tension due to insufficient moisture retention and cleaning power, when the pH is, for example, 5 to 6.

[0023] Furthermore, among these, from the viewpoint of cleaning power and / or reduced skin irritation, etc., preferred examples include N-acyl glutamic acid and N-acylaspartic acid having a saturated or unsaturated acyl group having 8 to 24 carbon atoms, and fatty acid amide sulfonic acids having 8 to 22 carbon atoms and salts thereof, more preferred examples include cocoyl glutamic acid, N-lauroyl aspartic acid, cocoyl methyl taurine and salts thereof, and even more preferred examples include triethanolamine cocoyl glutamate, sodium N-lauroyl aspartate, and sodium cocoyl methyl taurine.

[0024] These anionic surfactants may be used alone or in combination of two or more.

[0025] Examples of the nonionic surfactant used in the present invention include ester type, ether type, ester-ether type, alkanolamide type, alkylglycoside type, and alcohol type surfactants.

[0026] Nonionic surfactants are preferably used from the viewpoints of detergency and reduced skin irritation when the pH of the skin cleansing spray of the present invention is, for example, 5 to 8, preferably 5 to 6. Specific examples of ester-type surfactants include mono- or diesters of saturated or unsaturated fatty acids having 8 to 20 carbon atoms and glycerin, such as glycol dilaurate, glycol monostearate, glycol distearate, glyceryl monolaurate, glyceryl dilaurate, glyceryl monostearate, and glyceryl distearate; sorbitan fatty acid esters; and sucrose fatty acid esters.

[0027] Specific examples of the ether type surfactant include polyoxyethylene alkyl ether, polyoxyethylene alkyl phenyl ether, polyoxyethylene polyoxypropylene glycol, and the like.

[0028] Examples of ester / ether type surfactants include polyoxyethylene hydrogenated castor oil, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene hexitane fatty acid ester, and sorbitan fatty acid ester polyethylene glycol.

[0029] Specific examples of alkanolamide surfactants include cocamide DEA (coconut oil fatty acid diethanolamide), lauric acid diethanolamide, oleic acid diethanolamide, and stearic acid diethanolamide.

[0030] Specific examples of alkyl glycoside surfactants include octyl glucoside, decyl glucoside, and lauryl glucoside.

[0031] Examples of the alcohol-based surfactant include cetanol, stearyl alcohol, and oleyl alcohol.

[0032] Among these nonionic surfactants, from the viewpoint of obtaining better skin irritation reduction properties and cleaning power, preferably, ester / ether type surfactants and alkanolamide type surfactants are used, more preferably, polyoxyethylene hydrogenated castor oil and cocamide DEA are used, and even more preferably, polyoxyethylene hydrogenated castor oil is used.

[0033] These nonionic surfactants may be used alone or in combination of two or more.

[0034] Examples of the amphoteric surfactant that can be used in the present invention include alkyl betaine type, fatty acid amidopropyl betaine type, and amine oxide type surfactants.

[0035] Specific examples of alkyl betaine type surfactants include lauryl dimethyl amino acetate betaine, stearyl dimethyl amino acetate betaine, and octadecyl aminomethyl dimethyl sulfopropyl betaine.

[0036] Specific examples of fatty acid amidopropyl betaine type amphoteric surfactants include amidobetaines (amino acid-based amphoteric surfactants) such as cocamidopropyl betaine, and sulfobetaines such as cocamidopropyl hydroxysultaine.

[0037] Specific examples of the amine oxide type amphoteric surfactant include lauryl dimethylamine N-oxide and oleyl dimethylamine N-oxide.

[0038] These amphoteric surfactants may be in the form of a salt, for example, an alkali metal salt such as a sodium salt or a potassium salt; a triethanolamine (TEA) salt; an ammonium salt, or the like.

[0039] Among these amphoteric surfactants, from the viewpoint of obtaining better skin irritation reduction and cleaning power, fatty acid amidopropyl betaine type surfactants are preferred, more preferably amidobetaines (amino acid-based amphoteric surfactants) such as cocamidopropyl betaine, and even more preferably cocamidopropyl betaine.

[0040] These amphoteric surfactants may be used alone or in combination of two or more.

[0041] Examples of natural surfactants that can be used in the present invention include lecithin and lysolecithin; saponins such as quillaja saponin, soybean saponin, yucca saponin, soja saponin, beet saponin, adzuki bean saponin, carrot saponin, tea seed saponin, loofah saponin, and Centella saponin.

[0042] Lecithin is a mixture of phospholipids such as phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, and phosphatidylinositol, and other components such as triglycerides, fatty acids, and carbohydrates from vegetable oils, and is a well-known component in pharmaceuticals, quasi-drugs, and cosmetics.

[0043] The lecithin may be natural lecithin derived from animals or plants (e.g., soybean lecithin, egg yolk lecithin, etc.), a chemically treated product of natural lecithin, or a purified product of natural lecithin. Examples of chemically treated natural lecithin include hydrogenated lecithin obtained by hydrogenation (e.g., fully hydrogenated lecithin and partially hydrogenated lecithin), and hydroxylated lecithin obtained by hydroxylation. Examples of purified natural lecithin include lecithin with an increased phosphatidylcholine content using a solvent such as acetone.

[0044] Examples of lysolecithin include the lyso form of the above-mentioned lecithin (natural lecithin, chemically treated natural lecithin, and purified natural lecithin). Lysolecithin has a structure in which the fatty acid at the 2-position of phosphatidylcholine has been removed by hydrolysis (dissolution) of lecithin with an enzyme such as phospholipase A2.

[0045] Among these natural surfactants, from the viewpoint of obtaining better skin irritation reduction properties and cleaning power, preferred are lecithin, lysolecithin, and saponin, more preferred are lecithin and lysolecithin, and even more preferred is lysolecithin.

[0046] These natural surfactants may be used alone or in combination of two or more.

[0047] The content of the (A) component in the skin cleansing spray of the present invention is not particularly limited and can be appropriately determined according to the cleaning power to be imparted. Since the skin cleansing spray of the present invention can clean the skin without applying physical friction, the amount of surfactant in the skin cleansing spray can be significantly reduced compared to the amount contained in the conventional skin cleansing liquid composition, and the cleaning power can be effectively exerted even with a small amount of surfactant that does not inherently exert effective cleaning power. From this viewpoint, the content of the (A) component in the skin cleansing spray of the present invention is preferably 0.025 to 2% by weight. Furthermore, from the viewpoint of further suppressing skin irritation and a feeling of tightness due to insufficient moisturization, the upper limit of the above content range of the (A) component may be 1.5% by weight or less, preferably 1% by weight or less, more preferably 0.9% by weight or less, even more preferably 0.6% by weight or less, and even more preferably 0.2% by weight or less. On the other hand, from the viewpoint of obtaining better detergency, the lower limit of the range of the content of the (A) component is preferably 0.1 wt % or more, more preferably 0.5 wt % or more, even more preferably 1.5 wt % or more, and particularly preferably 1.8 wt % or more.

[0048] (B) Amphiphilic ester The skin cleansing spray of the present invention contains an amphiphilic ester as component (B). Component (B) does not exhibit a cleansing effect by itself, but by coexisting with component (A), it is possible to improve the cleansing power of the skin cleansing spray while maintaining low irritation.

[0049] In the present invention, the amphiphilic ester is one that dissolves at 2% by mass or more at room temperature in ion-exchanged water adjusted to a conductivity of 70 to 110 μs / m, when measured according to the method specified in the general testing methods of the Japanese Pharmacopoeia, and also dissolves at 10% by mass or more in the oil agent isotridecyl isononanoate (Salacos 913, manufactured by Nisshin Oillio Group, Ltd.) at room temperature (25° C.), and excludes ester-based surfactants.

[0050] The amphiphilic ester is not particularly limited, but from the viewpoint of obtaining better skin irritation reduction and cleaning power, it is preferable to select from the group consisting of dicarboxylic acid bis(polyoxyalkylene alkyl ether) ester, dicarboxylic acid dialkoxy alkyl ester, and (eicosane diacid / tetradecanedioic acid) polyglyceryl-10. As the amphiphilic ester, any one of dicarboxylic acid bis(polyoxyalkylene alkyl ether) ester, dicarboxylic acid dialkoxy alkyl ester, and (eicosane diacid / tetradecanedioic acid) polyglyceryl-10 may be used alone, or two or more kinds may be used in combination. Among these amphiphilic esters, dicarboxylic acid bis(polyoxyalkylene alkyl ether) ester is more preferable from the viewpoint of obtaining better skin irritation reduction and cleaning power.

[0051] The dicarboxylic acid bis(polyoxyalkylene alkyl ether) ester used in the present invention is a diester compound of a dicarboxylic acid and a polyoxyalkylene alkyl ether. Specific examples of the dicarboxylic acid constituting the diester compound of the dicarboxylic acid bis(polyoxyalkylene alkyl ether) ester include, for example, oxalic acid, malonic acid, succinic acid, tartaric acid, malic acid, glutaric acid, adipic acid, pemelic acid, suberic acid, azelaic acid, sebacic acid, aspartic acid, glutamic acid, acetone dicarboxylic acid, phthalic acid, and cyclohexane-1,4-dicarboxylic acid. In addition, examples of the polyoxyalkylene alkyl ether constituting the diester compound include, for example, polyoxyethylene monoalkyl ether, and more specifically, for example, diethylene glycol monoethyl ether and triethylene glycol monoethyl ether.

[0052] Among these dicarboxylic acid bis(polyoxyalkylene alkyl ether) esters, from the viewpoint of obtaining better skin irritation reduction properties and cleaning power, preferred are diester compounds of cyclohexane-1,4-dicarboxylic acid and diethylene glycol monoethyl ether, specifically, a compound called cyclohexane-1,4-dicarboxylic acid bisethoxydiglycol, represented by the INCI name (International Cosmetic Ingredient Dictionary and Handbook, 13th Edition, Vol. 1, CTFA, 2010, p. 331): BIS-ETHOXYDIGLYCOL CYCLOHEXANE 1,4-DICARBOXYLATE, and diester compounds of succinic acid and diethylene glycol monoethyl ether, specifically, a compound called cyclohexane-1,4-dicarboxylic acid bisethoxydiglycol, represented by the INCI name (International Cosmetic Ingredient Dictionary and Handbook, 13th Edition, Vol. 1, CTFA, 2010, p. 331-332): BIS-ETHOXYDIGLYCOL Examples of the compound include bisethoxydiglycol succinate, which is represented by SUCCINATE, and more preferably bisethoxydiglycol cyclohexane-1,4-dicarboxylate.

[0053] In the present invention, a specific example of the bis-ethoxydiglycol cyclohexane-1,4-dicarboxylate is "Neosolue-Aqulio (trade name)" manufactured by Nippon Fine Chemicals Co., Ltd., etc. In addition, a specific example of the bis-ethoxydiglycol succinate is "High Aquostar DCS (trade name)" manufactured by Kokyu Alcohol Kogyo Co., Ltd., etc.

[0054] These dicarboxylic acid bis(polyoxyalkylene alkyl ether) esters may be used alone or in combination of two or more.

[0055] The dicarboxylic acid dialkoxyalkyl ester used in the present invention is a diester compound of a dicarboxylic acid and an alkoxy alcohol. Specific examples of the dicarboxylic acid constituting the diester compound of the dicarboxylic acid dialkoxyalkyl include oxalic acid, malonic acid, succinic acid, tartaric acid, malic acid, glutaric acid, adipic acid, pemelic acid, suberic acid, azelaic acid, sebacic acid, aspartic acid, glutamic acid, acetone dicarboxylic acid, phthalic acid, and cyclohexane-1,4-dicarboxylic acid. Examples of the alkoxy alcohol constituting the diester compound include 2-methoxyethanol and 2-ethoxyethanol.

[0056] Among these dicarboxylate dialkoxyalkyl esters, from the viewpoint of obtaining the effects of the present invention more satisfactorily, a diester compound of succinic acid and 2-ethoxyethanol, specifically diethoxyethyl succinate, is preferable.

[0057] These dicarboxylic acid dialkoxyalkyl esters may be used alone or in combination of two or more.

[0058] The polyglyceryl-10 (eicosane diacid / tetradecanedioic acid) used in the present invention is not particularly limited, but examples thereof include "Neosolue-Aqua (trade name)" and "Neosolue-AquaS (trade name)" manufactured by Nippon Fine Chemical Co., Ltd.

[0059] The content of the (B) component in the skin cleansing spray of the present invention is not particularly limited, but may be, for example, 0.1% by weight or more. From the viewpoint of obtaining better cleaning power and / or further reducing the feeling of tightness due to insufficient moisturization, the content of the (B) component is preferably 0.5% by weight or more, more preferably 1.5% by weight or more, more preferably 2% by weight or more. The upper limit of the range of the content of the (B) component is not particularly limited, but from the viewpoint of the stability of the skin cleansing spray, for example, it may be 5% by weight or less, preferably 4% by weight or less, more preferably 3% by weight or less.

[0060] In the skin cleansing spray of the present invention, the ratio of the (A) component to the (B) component is not particularly limited and is determined by the above-mentioned respective contents. From the viewpoint of obtaining better skin irritation reduction properties and cleaning power, for example, the (B) component may be 0.1 to 100 parts by weight, preferably 0.1 to 10 parts by weight, more preferably 0.5 to 5 parts by weight, and even more preferably 1 to 5 parts by weight per part by weight of the (A) component.

[0061] Other Ingredients In addition to the above-mentioned components, the skin cleansing spray of the present invention may contain other bases and additives required for formulation, etc., within the scope of not impairing the effects of the present invention. Such additives are not particularly limited as long as they are pharma- ceutically acceptable, and examples thereof include aqueous bases such as water, lower alcohols having 1 to 5 carbon atoms (ethanol, isopropanol, etc.), and polyhydric alcohols (ethylene glycol, 1,3-butylene glycol (1,3-BG), propylene glycol, isoprene glycol, diethylene glycol, dipropylene glycol, polypropylene glycol, glycerin, etc.); preservatives (phenoxyethanol, methylparaben, propylparaben, benzoic acid, sodium benzoate, sorbic acid, etc.), flavoring agents (citral, 1,8-cineole, citronellal, farnesol, etc.), colorants (tar dyes (Brown No. 201, Blue No. 201, Yellow No. 4, Yellow No. 403, etc.), cacao dyes, chlorophyll, aluminum oxide, etc.), thickeners (hydroxypropylcellulose, hydroxyethylcellulose, crosslinked acrylic acid polymers, carboxyvinyl polymers, hypromellose, polyvinylpyrrolidone, sodium alginate, Examples of suitable additives include cellulose, ethyl cellulose, sodium carboxymethylcellulose, xanthan gum, carrageenan, etc.), pH adjusters (phosphoric acid, hydrochloric acid, formic acid, acetic acid, citric acid, glycolic acid, glucuronic acid, chloroacetic acid, succinic acid, fumaric acid, tartaric acid, maleic acid, malonic acid, malic acid, lactic acid, benzoic acid, potassium phosphate, dipotassium phosphate, disodium phosphate, trisodium phosphate, ammonium phosphate, pentasodium triphosphate, potassium citrate, sodium citrate (trisodium citrate), calcium citrate, sodium glycolate, sodium silicate, sodium succinate, trisodium sulfosuccinate, sodium fumarate, potassium tartrate, disodium tartrate, tetrapotassium pyrophosphate, disodium pyrophosphate, tetrasodium pyrophosphate, sodium borate, potassium sulfate, sodium hydrogen sulfate, sodium hydroxide, potassium hydroxide, triethanolamine, triisopropanolamine, etc., and preferably citric acid and potassium hydroxide.), wetting agents (sodium dl-pyrrolidone carboxylate solution, D-sorbitol solution, macrogol, etc.), stabilizers (dibutylhydroxytoluene, butylhydroxyanisole, sodium edetate, sodium metaphosphate, L-arginine, L-aspartic acid, DL-alanine, glycine, sodium erythorbate, propyl gallate, sodium sulfite, sulfur dioxide, chlorogenic acid, catechin, rosemary extract, etc.), antioxidants, ultraviolet absorbers, chelating agents, adhesives, buffers, dissolution aids, solubilizers, preservatives, and other additives. These substrates and additives may be used alone or in combination of two or more. The content of these substrates and additives can be appropriately set depending on the formulation, etc.

[0062] In addition to the above-mentioned components, the skin cleansing spray of the present invention may contain other pharmacological ingredients as necessary within the scope of not impairing the effects of the present invention. Examples of such pharmacological ingredients include vitamins (vitamin A, vitamin B1, vitamin B2, vitamin B5, vitamin B6, vitamin B12, vitamin C, vitamin D, vitamin K, niacin, folic acid, biotin, lycopene, etc.), antihistamines (diphenhydramine, diphenhydramine hydrochloride, etc.), local anesthetics (procaine, tetracaine, bupivacaine, mepivacaine, chloroprocaine, proparacaine, meprylcaine or salts thereof, orthocaine, oxethazaine, oxypolyethyleneoxydecane, Scotch extract, percaine, etc.), and the like. Examples of such pharmacological ingredients include minpase, tesitdesitin, etc.), anti-inflammatory agents (indomethacin, felbinac, diclofenac sodium, loxoprofen sodium, etc.), skin protectants (collodion, castor oil, etc.), blood circulation promoting ingredients (nonylic acid vanillylamide, nicotinic acid benzyl ester, capsaicin, chili pepper extract, etc.), cooling agents (menthol, camphor, borneol, peppermint water, peppermint oil, etc.), mucopolysaccharides (sodium chondroitin sulfate, glucosamine, hyaluronic acid, cationized hyaluronic acid (dihydroxypropyltrimonium hyaluronate, etc.), etc.). These pharmacological ingredients may be used alone or in combination of two or more. When these pharmacological ingredients are contained, the content may be appropriately set according to the type of pharmacological ingredient used, the expected effect, etc.

[0063] pH The pH of the skin cleansing spray of the present invention is adjusted to 3 to 8 from the viewpoint of reducing skin irritation and obtaining cleaning power. The preferred pH of the skin cleansing spray of the present invention may vary depending on the type of component (A), etc., but for example, when a carboxylic acid type amino acid anionic surfactant and / or a sulfonic acid type amino acid anionic surfactant is used as component (A), from the viewpoint of suppressing the feeling of tension due to insufficient moisture, or from the viewpoint of suppressing the feeling of tension due to insufficient moisture and cleaning power, it is preferably 3 to 6, more preferably 3 to 5, from the viewpoint of suppressing the feeling of tension due to insufficient moisture, it is even more preferably 3 to 4, and from the viewpoint of suppressing the feeling of tension due to insufficient moisture and cleaning power, it is even more preferably 5 to 6; when a nonionic surfactant is used as component (A), from the viewpoint of cleaning power and reducing skin irritation, it is preferably 5 to 8, more preferably 5 to 6. In the present invention, pH refers to the pH at 25°C.

[0064] form The skin cleansing spray of the present invention is in the form of a liquid or gel at room temperature. The viscosity of the skin cleansing spray of the present invention is 10,000 mPa·s or less, preferably 5,000 mPa·s or less at 20° C. The viscosity is measured using a BL viscometer (rotor No. 3, 6 rpm, 20° C.).

[0065] container The container for storing the skin cleansing spray of the present invention is not particularly limited, as long as it is a spray type container. The spray type container in the present invention is one that discharges the content in a mist state, and is different from a pump foamer container that discharges the skin cleansing agent composition in a foam state.

[0066] In the present invention, by storing the skin cleansing spray in a spray container in this manner, the skin cleansing spray is directly applied to the skin by spraying without foaming before application to the skin. Therefore, application to the skin is easy and physical friction by hands or the like during application can be avoided. Examples of the spray container include a pump spray container, which is a non-aerosol spray container, and an aerosol spray container. The aperture (inner diameter of the nozzle) of the spray container is, for example, 0.01 to 3 mmφ, preferably 0.1 to 1 mmφ. When the spray container is a pump spray container, the spray amount per push is, for example, 0.05 to 1.2 g, preferably 0.1 to 0.3 g.

[0067] Purpose The skin cleansing spray of the present invention is used to remove body fluids such as oil and grease, sweat, and dirt from the skin, and is not used as a makeup remover (cleansing). The skin cleansing spray of the present invention is used by applying it directly to the skin without diluting it with water or foaming it. The amount of use per application varies depending on the concentration of the surfactant and the degree of dirt, but for example, when used for face washing, it is 0.5 to 3 g, preferably 1 to 2 g.

[0068] More specifically, the skin cleaning spray can be directly sprayed from a spray container onto the area to be cleaned without taking it in the hand. By directly applying the skin cleaning spray to the area to be cleaned in this way, cleaning can be performed simply by utilizing the mechanical force of the liquid flow without any physical friction such as friction between the skin of the area to be cleaned and the hand, or between the skin of the area to be cleaned and the air bubbles. Since the skin cleaning spray of the present invention is a formulation with excellent cleaning power, cleaning using the mechanical force of the liquid flow without physical friction can significantly reduce the burden on the skin during cleaning, making it possible to perform an extremely gentle cleaning method. This type of cleaning method that does not create foam allows for quick cleaning, is easy to realize that it is gentle on the skin with less surfactant, and is also easy to satisfy consumers who are highly conscious of pursuing skin-friendly cleaning. The skin cleaning spray of the present invention is particularly suitable for cleaning methods that do not cause physical friction on the skin as described above, but does not exclude the use method of applying the skin cleaning spray to the area to be cleaned and then scrubbing with hands or the like.

[0069] The site to be cleaned by the skin cleansing spray of the present invention is not particularly limited since any body part can be cleaned, and examples thereof include hands, hair, scalp, body, face, etc. Since the skin cleansing spray of the present invention is applied to the site to be cleaned by spraying, it is suitable for use on hair, scalp, and body from the viewpoint of ease of application. In addition, since the skin cleansing spray of the present invention can exhibit excellent cleaning power without foaming in advance, it is suitable for use on the face, which is sensitive to irritation. Furthermore, since the skin cleansing spray of the present invention has low irritation and excellent cleaning power, it is particularly preferable to use it on sensitive skin. Sensitive skin refers to skin that is chronically or temporarily hypersensitive to specific components of topical agents (e.g., surfactants, preservatives, fragrances, etc.) and ultraviolet rays. Preferred examples of sensitive skin to which the skin cleansing spray of the present invention is applied include skin that has become chronically or temporarily sensitive enough to feel irritation when a skin cleansing spray containing component (A) and not containing component (B) is applied, and particularly includes skin that has become chronically or temporarily sensitive enough to feel irritation when a skin cleansing spray containing, for example, 0.025 to 2 wt % of component (A), not containing component (B), and adjusted to a pH of 3 to 8 is applied.

[0070] After washing, the skin cleansing spray can be washed off with water. When washing off with water, it may be done in the same manner as normal face washing, but from the viewpoint of reducing the burden on the skin, it is preferable to wash off using the mechanical force of a water flow without applying friction with the hands.

[0071] In addition, the surfactant concentration of the skin cleansing spray of the present invention can be extremely low, so in this case, it is not necessary to rinse it off after cleaning. Therefore, the skin cleansing spray of the present invention is also suitable for wiping purposes in hospitals, for skin cleansing treatments such as face washing in beauty salons and beauty parlors, and for disaster supplies, etc. If it is not rinsed off, the skin cleansing spray remaining on the cleaned area may be absorbed and removed using a water-absorbent substrate such as a towel or tissue.

[0072] Manufacturing method The skin cleansing spray of the present invention is produced by mixing the above-mentioned components (A) and (B) and other components that are blended as necessary, preparing the mixture to have a predetermined form and pH, and then storing the mixture in a spray container. When the mixture is stored in an aerosol spray container as a spray container, the mixture is stored together with a propellant such as gas before production. EXAMPLES

[0073] The present invention will be described in more detail below with reference to examples, but the present invention is not limited to these.

[0074] [Reference test example] Skin cleansing sprays were prepared with the compositions shown in Tables 1 to 4. Details of each component shown in Tables 1 to 4 are as follows. The skin cleansing sprays shown in Tables 1 to 4 are liquids, and all had a viscosity at 20°C (measured with a BL viscometer (Brookfield B-type viscometer) rotor No. 3, 6 rpm) in the range of 5000 mPa s or less, and the pH at 25°C was in the range of 3 to 8 except for Reference Example 1 (pH at 25°C was about 10). Sodium laurate (NOF Corp. "NonSal LN-1" (product name) TEA-Cocoyl Glutamate (Amisoft CT-12S (product name) manufactured by Ajinomoto Co., Inc.) Sodium methyl cocoyl taurate (NOF Corp. "Diapon K-SF (product name)") Sodium N-lauroyl aspartate solution (20% by weight) (Asahi Kasei Fine Chemical Corporation's "Aminoformer FLDS-L (product name)") Polyoxyethylene lauryl ether acetate (Kao Corporation "Kao Akipo RLM-45 (product name)") Cocamide DEA ("Amizol CDE-G (product name)" manufactured by Kawaken Fine Chemical Co., Ltd.) PEG-60 hydrogenated castor oil (polyoxyethylene hydrogenated castor oil; "NIKKOL HCO-60 (product name)" manufactured by Nikko Chemicals Co., Ltd.) Polyoxyethylene sorbitan monostearate (Kao Corporation, Rheodor TW-S120V) Glycerol mono-2-ethylhexyl ether (SEPPIC "sensiva SC 50 JP (product name)”) Cocamidopropyl betaine ("Softazoline CPB (product name)" manufactured by Kawaken Fine Chemicals Co., Ltd.) Lauryl hydroxysulfobetaine solution (30% by weight) ("Amphitol 20HD" (product name) manufactured by Kao Corporation) Lysolecithin ("Lysolecithin Kyowa" manufactured by Kyowa Hakko Bio Co., Ltd.) Quillaja japonica extract (Maruzen Pharmaceutical Co., Ltd. "Quillaja japonica extract BG", saponin content 5% by weight) Cyclohexane-1,4-dicarboxylate bisethoxydiglycol ("Neosolue-Aqulio" (product name) manufactured by Nippon Fine Chemical Co., Ltd.) Bisethoxydiglycol succinate ("High Aquostar DCS (product name)" manufactured by Kokyu Alcohol Kogyo Co., Ltd.)

[0075] <Cleaning power evaluation> The prepared skin cleansing sprays were evaluated for their cleansing power by 10 panelists specializing in cosmetic evaluation. Specifically, each skin cleansing spray was placed in a pump-type spray container (Takemoto Container Co., Ltd.'s "Z-155-C110 (trade name)" spray amount per push: 0.15 g), and 1.5 g was applied by spraying directly onto the face. The spray was left for about 5 seconds, and then the face was washed with water without touching the hands to the face. After holding the face with a towel to absorb the water, the feeling of removing dirt from the skin was scored by sensory evaluation based on the following index.

[0076] 5 points: Dirt was thoroughly removed 4 points: Dirt was removed 3 points: Neither 2 points: Not much dirt is removed 1 point: No dirt is removed at all

[0077] The scores obtained by the 10 panelists were totaled and the degree of cleaning power was evaluated according to the following classification. The results are shown in Tables 1 to 4. ◎: 45 points or more ○: 40 points or more and less than 45 points △: 35 points or more but less than 40 points ×: Less than 35 points

[0078] <Evaluation of tightness> The prepared skin cleansing sprays were evaluated for their feeling of tightness by 10 panelists specializing in cosmetic evaluation. Specifically, each skin cleansing spray was placed in a pump-type spray container ("Z-155-C110 (product name)" (amount sprayed per push is 0.15g) and 1.5g was applied by spraying directly onto the face. The product was left for about 5 seconds, after which the skin was washed with water without touching the face with hands. After holding the face with a towel to absorb the water, the feeling of tightness immediately after washing was evaluated by sensory evaluation and scored based on the following index. The stronger the feeling of tightness, the more insufficient moisture was indicated.

[0079] 5 points: No feeling of tightness at all 4 points: Almost no feeling of tension 3 points: Only a slight feeling of tightness 2 points: Feeling of tension 1 point: Strong feeling of tension

[0080] The scores obtained by the 10 panelists were totaled, and the degree of tightness was evaluated according to the following classification. The results are shown in Tables 3 and 4. ◎: 45 points or more ○: 40 points or more and less than 45 points △: 35 points or more but less than 40 points ×: Less than 35 points

[0081] <Cultured epidermis skin irritation test (in vitro evaluation of skin irritation)> The prepared skin cleansing spray was subjected to a cultured epidermis skin irritation test as follows. 1. Preparation of the Cultured Epidermal Model LabCyte EPI-MODEL24 The assay medium was warmed and added to a 24-well assay plate in 0.5 mL portions. The cultured epidermis model LabCyte EPI-MODEL24 (lot number: LCE24-180226-A) was transferred to the 24-well assay plate to which the assay medium had been added. After confirming that there were no air bubbles on the bottom of the culture cup, the cup was placed in a CO2 incubator and left to stand for at least 1 hour before exposure to the test substance.

[0082] 2. Test Substance Application and Washing Of the 24 epidermal models, 12 were used (the remaining ones were kept in preculture until the main test). The 24-well assay plate was removed from the CO2 incubator. The assay medium was warmed and added in 1.0 mL portions to the third row of the 24-well assay plate. 25 μL of the test substance (each skin cleansing spray agent) was dropped onto the cultured epidermis in the culture cup without using a pump-type spray container, and exposed to the entire surface. After 1, 5, and 10 minutes of exposure, the test substance was removed by suction, and the cultured epidermal model in the cup was washed with phosphate buffer solution (PBS) and transferred to the third row of the 24-well assay plate.

[0083] 3.MTT Test The MTT test is a method to detect the intracellular uptake of MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide]. This method measures cell viability by extracting the formazan dye produced when [de] is reduced by mitochondrial dehydrogenase inside the cell with an organic solvent and measuring the absorbance at 570 nm.

[0084] 10 mL of MTT medium was prepared with a final concentration of 0.5 mg / mL. The MTT medium was warmed and added in 0.5 mL portions to the fourth row of a 24-well assay plate. The cultured epidermal model was transferred to the fourth row of a 24-well assay plate and placed in a CO2 incubator to carry out the MTT reaction for 3 hours. After the MTT reaction was completed, the cultured skin was picked up with tweezers and transferred to a 1.5 mL microtube. 300 μL of isopropanol was added to the microtube to completely immerse the cultured epidermal model. After leaving it for 2 hours, the microtube was vortexed to extract the pigment. The extract (200 mL) was added to each well of a 96-well plate. In addition, 200 μL of isopropanol was added to A1 as a blank (negative control). The absorbance at 570 nm and 650 nm was measured using a microplate reader. The absorbance at 650 nm was subtracted from the absorbance at 570 nm to obtain the measured value, and the cell viability of the test substance was calculated according to the following formula.

[0085]

number

[0086] The cell viability was classified based on the following criteria, and the skin irritation was evaluated. The results are shown in Tables 3 and 4. ◎: 90% or more ○: 75% or more but less than 90% △: 65% or more but less than 75% ×: 50% or more but less than 65% ××: Less than 50%

[0087] As shown in Tables 1 to 4, no cleaning power was observed in the skin cleansing sprays (Reference Comparative Examples 1 to 10) containing a surfactant alone at a concentration of 0.025 to 2% by weight. In contrast, the skin cleansing sprays (Reference Examples 1 to 20) containing an amphiphilic ester (Reference Comparative Examples 11 to 15) that does not show cleaning power alone together with a surfactant at a concentration of 0.025 to 2% by weight were able to obtain excellent cleaning power by simply spraying the skin from a spray container and using the mechanical force of the liquid flow without any physical friction. In other words, it was shown that cleaning that is gentle on the skin is possible.

[0088] In addition, as shown in Reference Examples 1 to 3, a skin cleansing spray containing more than 2% by weight of a surfactant alone can also provide excellent detergency simply by being directly applied to the skin by spraying. On the other hand, considering the skin irritation caused by the surfactant concentration shown in Reference Examples 1 to 3, when the surfactant concentration was set to 2% by weight or less as shown in Reference Examples 9 to 20, not only excellent detergency but also excellent low irritation was achieved. That is, it was shown that by setting the surfactant concentration of the skin cleansing spray directly applied to the skin by spraying to 0.025 to 2% by weight, gentle cleansing of the skin both physically and chemically becomes possible.

[0089]

Table 1

[0090]

Table 2

[0091]

Table 3

[0092]

Table 4

[0093] [Test Example] Skin cleansing sprays having the compositions shown in Tables 5 to 6 were prepared. The details of each component shown in Tables 5 to 6 are as shown in the reference test examples. The skin cleansing sprays shown in Tables 5 to 6 were expected, and their viscosities at 20°C (measured with a Brookfield viscometer (Model B viscometer manufactured by Brookfield Engineering Laboratories, Inc.), rotor No. 3, 6 rpm) were also all in the range of 5000 mPa·s or less.

[0094] <pH Measurement> For the prepared skin cleansing agent composition, the pH at 25°C was measured using a desktop pH meter (F-72) manufactured by HORIBA.

[0095] <Cleaning power evaluation> The prepared skin cleansing composition was evaluated for its detergency in the same manner as in the Reference Test Example, and the results are shown in Tables 5 to 6.

[0096] <Irritation Evaluation> The prepared skin cleansing compositions were evaluated for irritation by 10 panelists specializing in cosmetic evaluation. Specifically, each skin cleansing composition was placed in a pump-type spray container ("Z-155-C110 (product name)" (amount sprayed per push is 0.15 g) manufactured by Takemoto Container Co., Ltd.) and 1.5 g was applied by spraying directly onto the entire body. The composition was left for about 5 seconds, and then washed off with water without touching the skin with hands. After holding the skin with a towel to absorb the water, the irritation was evaluated by sensory evaluation and scored based on the following criteria.

[0097] 5 points: No irritation felt at all 4 points: I didn't feel much stimulation. 3 points: Slight irritation felt 2 points: I felt irritation 1 point: Strong stimulation felt

[0098] The scores obtained by the 10 panelists were totaled and the degree of irritation was evaluated according to the following classification. The results are shown in Tables 5 to 6. ◎: 45 points or more ○: 40 points or more and less than 45 points △: 35 points or more but less than 40 points ×: Less than 35 points

[0099] <Evaluation of tightness> The degree of the tightness was evaluated in the same manner as in the Reference Test Example, except that the evaluation of the tightness was performed not only immediately after washing, but also 5 minutes and 10 minutes after washing. The results are shown in Tables 5 and 6.

[0100] As shown in Tables 5-6, in the skin cleansing sprays (Examples 1-15) containing 2% by weight of surfactant, amphiphilic ester, and pH adjusted to 3-8, it was found that excellent cleansing power could be obtained simply by spraying directly onto the skin from a spray container, without any physical friction, and by utilizing the mechanical force of the liquid flow. In addition, in the skin cleansing sprays (Comparative Examples 1-5) containing 2% by weight of surfactant and amphiphilic ester, but with a pH below 3, irritation was increased, and depending on the type of surfactant, a decrease in cleansing power and an increase in tightness due to insufficient moisturization were observed, while in the skin cleansing sprays (Comparative Examples 6-10) containing a pH above 8, a increase in tightness due to insufficient moisturization were observed, and depending on the type of surfactant, an increase in irritation and a decrease in cleansing power were observed.

[0101] [Table 5]

[0102] [Table 6]

Claims

1. A skin cleansing spray agent containing (A) an anionic surfactant, a nonionic surfactant, an amphoteric surfactant, and / or a natural surfactant, and (B) an amphiphilic ester selected from the group consisting of a dicarboxylate bis(polyoxyalkylene alkyl ether) ester, a dicarboxylate dialkoxyalkyl ester, and polyglyceryl-10 (eicosadioate / tetradecanedioate), having a pH of 3 to 8, and contained in a spray-type container that is not a pump foamer container and discharges in a foam state, It is used to spray directly onto the hands, body, or face, and to cleanse using the mechanical force of the liquid flow, and then to rinse with water or to absorb and remove the skin cleansing spray remaining on the cleansed area using a water-absorbent substrate; and A skin cleansing spray that is not to be used as a makeup remover.

2. A skin cleansing spray agent containing (A) a surfactant as a cleansing component and (B) an amphiphilic ester selected from the group consisting of a dicarboxylate bis(polyoxyalkylene alkyl ether) ester, a dicarboxylate dialkoxyalkyl ester, and polyglyceryl-10 (eicosadioate / tetradecanedioate), having a pH of 3 to 8, and contained in a spray-type container that is not a pump foamer container and discharges the agent in a foam state, It is used to spray directly onto the hands, body, or face, and to cleanse using the mechanical force of the liquid flow, and then to rinse with water or to absorb and remove the skin cleansing spray remaining on the cleansed area using a water-absorbent substrate; and A skin cleansing spray that is not to be used as a makeup remover.

3. 3. The skin cleansing spray according to claim 1, wherein the spray container is a pump-type spray container.

4. 3. The skin cleansing spray according to claim 1, wherein the spray container is an aerosol spray container.

5. 5. The skin cleansing spray according to claim 1, wherein the dicarboxylic acid bis(polyoxyalkylene alkyl ether) ester is cyclohexane-1,4-dicarboxylate bisethoxydiglycol.

6. The skin cleansing spray according to any one of claims 1 to 5, wherein the content of the component (A) is 0.025 to 2% by weight.

7. The skin cleansing spray according to any one of claims 1 to 6, which is applied to sensitive skin.

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