Lymphatic system testing device

Abstract

To provide a lymphatic system examination device suitable for lymphatic system examination in a lower half of a subject's body.SOLUTION: A lymphatic system examination device is equipped with a placing part 21 on which a subject S injected with fluorescent dye in the lymphatic system stands, and includes a body part 2 for having a lower half L of the body of the subject S positioned in an imaging region R on the placing part 21, an illumination part 3 for irradiating the lower half L of the body with excitation light, and an imaging part 4 for detecting fluorescence emitted from the lower half L of the body according to the irradiation of the excitation light. The illumination part 3 and the imaging part 4 are arranged on one side in an X-direction with respect to the imaging region R. The body part 2 further includes a regulation part 26. The regulation part 26 is arranged along an upper end part Ra of the imaging region R, and regulates movement of the subject S to the one side in the X-direction.SELECTED DRAWING: Figure 3

Description

[Technical Field]

[0001] The present invention relates to a lymphatic system testing device. [Background technology]

[0002] The lymphatic system is a network that functions as a circulatory system for lymphatic fluid, and is composed of lymph nodes, lymphatic vessels, etc. A known testing method for diagnosing lymphatic system diseases (e.g., lymphedema) involves irradiating a predetermined site of a subject, whose lymphatic system has been injected with a fluorescent dye such as indocyanine green, with excitation light, and detecting fluorescence emitted from the predetermined site in response to the irradiation of the excitation light, thereby obtaining a fluorescent image of the predetermined site (see, for example, Patent Document 1). [Prior art documents] [Patent documents]

[0003] [Patent Document 1] Japanese Patent Application Publication No. 2019-118803 Summary of the Invention [Problem to be solved by the invention]

[0004] The devices used in the above-described tests have a problem in that the irradiation range of excitation light and the detection range of fluorescence are limited to a narrow range, making it difficult to efficiently test the lymphatic system in the lower body of a subject.

[0005] An object of the present invention is to provide a lymphatic system examination device suitable for examining the lymphatic system in the lower body of a subject. [Means for solving the problem]

[0006] The lymphatic system examination device of the present invention is [1] "a lymphatic system examination device having a mounting section on which a subject whose lymphatic system has been injected with a fluorescent dye stands, and comprising: a main body section for positioning the lower body of the subject in an imaging area on the mounting section; an illumination section for irradiating the lower body with excitation light; and an imaging section for detecting fluorescence emitted from the lower body in response to the irradiation with the excitation light, wherein the illumination section and the imaging section are arranged on one side of the imaging area in a first horizontal direction, and the main body section further has a restriction section that is arranged along the upper end of the imaging area and restricts movement of the subject to the one side in the first horizontal direction."

[0007] In the lymphatic system examination device described in [1] above, the illumination unit and the imaging unit are arranged on one side in the first horizontal direction of the imaging area in which the lower half of the subject's body is located, and a restricting unit arranged along the upper end of the imaging area restricts movement of the subject to that side in the first horizontal direction. This makes it possible to maintain constant the distance between the illumination unit and the lower half of the subject's body and the distance between the imaging unit and the lower half of the subject's body, and to suppress shaking of the lower half of the subject's body. Therefore, the lymphatic system examination device described in [1] above can obtain a fluorescent image of the lower half of the subject's body that is appropriate for examining the lymphatic system in the lower half of the body.

[0008] The lymphatic system examination device of the present invention may be [2] "the lymphatic system examination device described in the above [1], further comprising a first plate for brightness calibration arranged on a surface of the restriction part on the side of the imaging part, the first plate extending in a second horizontal direction perpendicular to the first horizontal direction." The lymphatic system examination device described in [2] can adjust the brightness of each acquired fluorescent image.

[0009] The lymphatic system examination device of the present invention may be [3] "the lymphatic system examination device described in [1] or [2] above, further comprising a scale arranged on the surface of the restriction part on the side of the imaging part, the restriction part extending in a second horizontal direction perpendicular to the first horizontal direction." With the lymphatic system examination device described in [3], the size of each part of the lower body can be determined from the acquired fluorescent image.

[0010] The lymphatic system examination device of the present invention may be [4] "the lymphatic system examination device according to any one of the above [1] to [3], further comprising a second plate for brightness calibration detachable from the main body, the second plate being arranged on the main body so as to be positioned in the imaging area while contacting the restriction portion from the side opposite to the imaging portion." The lymphatic system examination device according to [4] allows the brightness of the fluorescent image to be adjusted for each lymphatic system examination device.

[0011] The lymphatic system examination device of the present invention may be [5] "the lymphatic system examination device according to any one of the above [1] to [4], further comprising a distance sensor arranged on the one side of the imaging region in the first horizontal direction and measuring the distance to the lower body located in the imaging region." The lymphatic system examination device according to [5] can accurately grasp the position of the lower body of the subject in the first horizontal direction. [Effects of the Invention]

[0012] According to the present invention, it is possible to provide a lymphatic system examination device suitable for examining the lymphatic system in the lower body of a subject. [Brief explanation of the drawings]

[0013] [Figure 1] 1 is a perspective view of a lymphatic system examination device according to an embodiment; [Figure 2] FIG. 2 is a perspective view of the device main body shown in FIG. [Figure 3] 3 is a cross-sectional view of the device body taken along line III-III shown in FIG. 2. FIG. [Figure 4] 4 is a cross-sectional view of the device body taken along line IV-IV shown in FIG. 3. FIG. [Figure 5] 4 is a cross-sectional view of the device body taken along line VV shown in FIG. 3. [Figure 6] FIG. 3 is a cross-sectional view of a restriction portion shown in FIG. 2. [Figure 7]FIG. 10 is a cross-sectional view of the device body on which the second plate for brightness calibration is disposed. [Figure 8] FIG. 2 is a diagram showing a visible light image of an object. [Figure 9] FIG. 9 is a diagram showing a display unit on which multiple types of fluorescent images of the object shown in FIG. 8 are displayed. [Figure 10] FIG. 10 is a plan view of a device main body according to a modified example. DETAILED DESCRIPTION OF THE INVENTION

[0014] Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings. In each drawing, the same or corresponding parts are designated by the same reference numerals, and duplicated explanations will be omitted.

[0015] The lymphatic system examination device 1 shown in Fig. 1 is a device that performs an examination of the lymphatic system of the lower body of a subject S in order to diagnose a lymphatic system disease (e.g., lymphedema). More specifically, the lymphatic system examination device 1 is a device that irradiates excitation light onto the lower body of a subject S, whose lymphatic system has been injected with a fluorescent dye such as indocyanine green, and detects fluorescence emitted from the lower body in response to the irradiation with the excitation light, thereby obtaining a fluorescent image of the lower body. Hereinafter, the vertical direction will be referred to as the Z direction, the first horizontal direction will be referred to as the X direction, and the second horizontal direction perpendicular to the first horizontal direction will be referred to as the Y direction.

[0016] As shown in FIG. 1, the lymphatic system testing device 1 includes a device main body 10, a control unit 11, a display unit 12, and an input unit 13. The control unit 11 is composed of a processing unit and a storage unit. The processing unit of the control unit 11 is a computer device composed of a processor, memory, storage, communication devices, etc., and processes various data by executing software (programs). The storage unit of the control unit 11 is a hard disk or the like, and stores various data. The display unit 12 is a display or the like, and displays various data to the operator. The input unit 13 is a mouse, keyboard, etc., and accepts input of various data from the operator.

[0017] As shown in Figures 2, 3, 4, and 5, the device main body 10 includes a main body section 2. The main body section 2 has a base section 21 and a support section 22. In the main body section 2, the base section 21 is the section on which the subject S stands, and the support section 22 is the section located on one side of the base section 21 in the X direction. The main body section 2 positions the lower body L of the subject S (i.e., the section from the lower abdomen to the toes) in the imaging area R on the base section 21. A plurality of casters 23 are attached to the underside of each of the base section 21 and the support section 22. This allows the device main body 10 to move smoothly.

[0018] The main body 2 further includes a frame 24 and a wall 25. The frame 24 is composed of a first frame 241 and a second frame 242. The first frame 241 is attached to the mounting portion 21, and the second frame 242 is attached to the support portion 22. The wall 25 is composed of a first wall 251 and a second wall 252. The first wall 251 is attached to the mounting portion 21 via the first frame 241, and the second wall 252 is attached to the support portion 22 via the second frame 242. The unit composed of the support portion 22, the second frame 242, and the second wall 252 is detachable from the unit composed of the mounting portion 21, the first frame 241, and the first wall 251. As an example, the width of each unit in the X direction and the width of each unit in the Y direction are 70 cm or less. This improves the portability of each unit.

[0019] The wall 25 forms a housing 250 on the mounting section 21 and the support section 22. The housing 250 defines an imaging area R on the mounting section 21. An opening 25a is formed in the housing 250 so as to face the mounting section 21 across the imaging area R. The waist of the subject S is located inside the opening 25a. In other words, the wall 25 forms the opening 25a inside which the subject S is placed. The inner surface of the housing 250 is, for example, black. Note that the first wall 251 has a wall portion 251a opposite to the second wall 252 that forms a door. This allows the subject S to get on and off the mounting section 21.

[0020] The main body 2 further includes a restricting portion 26. The restricting portion 26 is disposed along the upper end portion Ra of the imaging region R. The restricting portion 26 restricts movement of the subject S to one side (the support portion 22 side) in the X direction. In this embodiment, the restricting portion 26 extends in the Y direction along the upper end portion Ra of the imaging region R, and is hung across the first frame 241 while crossing the opening 25a. As shown in FIG. 6, the restricting portion 26 is composed of a bar material 261 and a cushion material 262. The bar material 261 is a core material hung across the first frame 241. The cushion material 262 is an elastic material wrapped around the bar material 261.

[0021] 2, 3, 4, and 5, the device main body 10 further includes an illumination unit 3, an imaging unit 4, and a distance sensor 5. The illumination unit 3, the imaging unit 4, and the distance sensor 5 are arranged on one side in the X direction (the support unit 22 side) of the imaging region R. The housing 250 accommodates the illumination unit 3, the imaging unit 4, and the distance sensor 5 on the support unit 22.

[0022] The illumination unit 3 irradiates the lower body L with excitation light. The illumination unit 3 has a first light-emitting region 31 and a second light-emitting region 32 arranged side by side and spaced apart in the Y direction. The first light-emitting region 31 and the second light-emitting region 32 each extend in the Z direction facing the imaging region R. The first light-emitting region 31 and the second light-emitting region 32 are arranged so that the closer they are to the imaging region R in the X direction, the farther they are from each other in the Y direction. The first light-emitting region 31 includes multiple first light-emitting portions 31a, and the second light-emitting region 32 includes multiple second light-emitting portions 32a. The illumination unit 3 has a function of adjusting the light emission intensity of each first light-emitting portion 31a and each second light-emitting portion 32a. Each of the first light-emitting portion 31a and the second light-emitting portion 32a is composed of multiple LEDs that emit light having a center wavelength of, for example, 735 nm. The illumination unit 3 is attached to the second frame 242. That is, the illumination unit 3 is supported by the support unit 22 via the second frame 242.

[0023] The imaging unit 4 detects fluorescence emitted from the lower body L in response to irradiation with excitation light. The imaging unit 4 faces the imaging region R across the region between the first light-emitting region 31 and the second light-emitting region 32. The imaging unit 4 is disposed on one side in the X direction (the opposite side to the imaging region R) of the illumination unit 3. In other words, the illumination unit 3 is located between the imaging region R and the imaging unit 4 in the X direction. The imaging unit 4 is located in the center of the imaging region R when viewed from the X direction. In this embodiment, the imaging unit 4 is attached to a bar member 242a, which is a member of the second frame 242 extending upward from the support unit 22 side. In other words, the imaging unit 4 is supported by the support unit 22 via the second frame 242.

[0024] As an example, the imaging unit 4 is composed of a photodetector, a filter arranged in front of the photodetector, and a lens arranged in front of the filter. The photodetector uses an area sensor (e.g., CCD, CMOS, etc.) that is sensitive to fluorescence (e.g., light in the near-infrared region). The filter uses a vapor deposition filter that selectively transmits fluorescence. The filter may include an absorption filter to remove the effects of oblique light. The lens uses a wide-angle lens so that the entire lower body L can be imaged.

[0025] The distance sensor 5 measures the distance to the lower body L located in the imaging region R. The distance sensor 5 may be, for example, an ultrasonic distance sensor or an optical distance sensor using a triangulation method or a ToF method. The distance sensor 5 faces the imaging region R across the region between the first light-emitting region 31 and the second light-emitting region 32. The distance sensor 5 is disposed on one side of the illumination unit 3 in the X direction (the opposite side to the imaging region R). When viewed from the X direction, the distance sensor 5 is located at the center of the imaging region R in the Y direction. In this embodiment, the distance sensor 5 is attached to a bar member 242b, which is a member of the second frame 242 extending downward from the opposite side to the support unit 22. In other words, the distance sensor 5 is supported by the support unit 22 via the second frame 242. Based on the distance measured by the distance sensor 5, the light emission intensity of the illumination unit 3 may be adjusted so that the intensity of the excitation light irradiated on the lower body L is uniform. Such adjustment of the light emission intensity of the illumination unit 3 may be performed based on the intensity of the excitation light detected by a separately provided photodetector.

[0026] As shown in FIG. 3 , the device main body 10 includes a camera 6. The camera 6 is attached to the first frame 241 so as to face the mounting portion 21 and not be within the field of view of the imaging unit 4. The housing 250 accommodates the camera 6 on the mounting portion 21. The space inside the housing 250 is made into a darkroom by a cover 7 that covers the opening 25a when the camera 6 is worn by the subject S. The camera 6 captures images of the feet of the subject S in the darkroom space inside the housing 250. Therefore, the camera 6 may be configured with a lighting device and an imaging device, or may be configured with only an imaging device such as an infrared camera. The image captured by the camera 6 is displayed on the display unit 12 and shown to the subject S. The camera 6 may be attached to the restriction unit 26 or the second frame 242. When the camera 6 is configured with a lighting device and an imaging device, the lighting device may be separated from the imaging device.

[0027] As shown in FIG. 5, the mounting unit 21 is provided with a positioning unit 8 that indicates the standing position of the subject S. In this embodiment, the positioning unit 8 includes a footprint 81 when the subject S faces the imaging unit 4, and a footprint 82 when the subject S faces away from the imaging unit 4. Each of the footprints 81, 82 is a mark formed on the mounting surface 21a of the mounting unit 21. The positioning unit 8 is imaged by the camera 6.

[0028] As shown in FIG. 6, a first plate 14 and a scale 15 are attached to a surface 26a of the restriction portion 26 facing the imaging portion 4. The first plate 14 is a plate for brightness calibration. As an example, the first plate 14 is made of multiple types of materials (e.g., cloth and acrylic plate) that emit fluorescent light with different intensities in response to irradiation with excitation light. The scale 15 is a member having graduations indicating length. As shown in FIG. 7, a second plate 16 is detachably attached to the main body portion 2. The second plate 16 is arranged on the main body portion 2 so as to be positioned in the imaging region R while contacting the restriction portion 26 from the side opposite the imaging portion 4. The second plate 16 is a plate for brightness calibration, and is, for example, an acrylic plate.

[0029] In the lymphatic system examination device 1 configured as described above, the control unit 11 is electrically connected to each of the illumination unit 3, the imaging unit 4, the distance sensor 5, the camera 6, the display unit 12, and the input unit 13. The control unit 11 controls the illumination unit 3 to emit excitation light as a flash in synchronization with the imaging timing of the imaging unit 4. This makes it possible to suppress changes in the amount of excitation light irradiated on the lower body L when the lower body L is imaged. The control unit 11 generates a fluorescent image of the lower body L based on the fluorescence detected by the imaging unit 4 and controls the display unit 12 to display the fluorescent image of the lower body L. The control unit 11 stores fluorescent images of the lower body L previously generated for the subject S and can control the display unit 12 to display the previously generated fluorescent image of the lower body L and the newly generated fluorescent image of the lower body L side by side. The control unit 11 can also control the display unit 12 to display the visible light image of the lower body L and the fluorescent image of the lower body L side by side. Furthermore, the control unit 11 can control the display unit 12 so that a portion of at least one image (visible light image, fluorescent image) of the lower body L is enlarged based on instructions input to the control unit 11 via the input unit 13.

[0030] In this embodiment, the control unit 11 controls at least one of the illumination unit 3 and the image capture unit 4 to change at least one of the light emission time of the illumination unit 3 and the exposure time of the image capture unit 4, thereby generating multiple types of fluorescent images as fluorescent images of the lower body L, and controls the display unit 12 to display the multiple types of fluorescent images side by side. That is, the lymphatic system examination device 1 implements a lymphatic system examination method including the steps of: generating multiple types of fluorescent images as fluorescent images of the lower body L by controlling at least one of the illumination unit 3 and the image capture unit 4 to change at least one of the light emission time of the illumination unit 3 and the exposure time of the image capture unit 4 (i.e., to change the exposure amount in the image capture unit 4); and controlling the display unit 12 to display the multiple types of fluorescent images side by side.

[0031] In this lymphatic system examination method, the control unit 11 generates each of the multiple types of fluorescent images in a time of 1 second or less (i.e., 1 second or less after an image capturing instruction is input to the control unit 11 via the input unit 13). Note that the exposure amount in the image capturing unit 4 may be changed by changing at least one of the light emission time of the illumination unit 3, the light emission intensity of the illumination unit 3, the exposure time of the image capturing unit 4, the sensor gain of the image capturing unit 4, and the lens aperture of the image capturing unit 4.

[0032] FIG. 8 is a diagram showing a visible light image of an object, and FIG. 9 is a diagram showing a display unit 12 displaying multiple fluorescent images I of the object shown in FIG. 8. The object shown in FIG. 8 is an arm model with a fluorescent substance attached extending in the vertical direction and wrapped in white paper. The white paper covers the fluorescent substance in single, double, and triple layers, from top to bottom. The multiple fluorescent images I shown in FIG. 9 are images generated when the light emission time of the illumination unit 3 and the exposure time of the image capture unit 4 are set to 1000 ms, 500 ms, 250 ms, 125 ms, and 62.5 ms. In the single white paper area, if the light emission time of the illumination unit 3 and the exposure time of the image capture unit 4 are 500 ms or longer, the fluorescent substance appears much thicker than the actual fluorescent substance due to scattering of the fluorescent light. In the double white paper area, the fluorescent substance is visible when the light emission time of the illumination unit 3 and the exposure time of the image capture unit 4 are 125 ms or longer. In the triple white paper portion, the fluorescent material is visible when the light emission time of the illumination unit 3 and the exposure time of the image capture unit 4 are 500 ms or more. From the above, it can be seen that by adjusting at least one of the light emission time of the illumination unit 3 and the exposure time of the image capture unit 4, the state of the lymphatic system in the lower body L can be appropriately grasped.

[0033] As described above, in the lymphatic system examination device 1, the first light-emitting region 31 and the second light-emitting region 32 of the illumination unit 3 each extend in the Z direction while facing the imaging region R, and the imaging unit 4 faces the imaging region R via the region between the first light-emitting region 31 and the second light-emitting region 32. This allows excitation light to be uniformly irradiated onto the lower body L of the subject S located in the imaging region R, and fluorescence emitted from the lower body L in response to the uniform irradiation of excitation light can be detected. Therefore, the lymphatic system examination device 1 can acquire a fluorescent image of the lower body L of the subject S that is appropriate for examining the lymphatic system in the lower body L.

[0034] In the lymphatic system examination device 1, when viewed from the X direction, the imaging unit 4 is positioned at the center of the imaging region R. This makes it possible to prevent distortion from occurring in the acquired fluorescent image.

[0035] In the lymphatic system examination device 1, the illumination unit 3 is located between the imaging region R and the imaging unit 4 in the X direction. This allows the excitation light to be more uniformly irradiated onto the lower body L of the subject S located in the imaging region R.

[0036] In the lymphatic system examination device 1, the illumination unit 3 has a function of adjusting the light emission intensity of each of the first light-emitting portions 31 a and each of the second light-emitting portions 32 a. This allows the excitation light to be uniformly irradiated onto the lower body L of the subject S located in the imaging region R, depending on the shape of the lower body L, etc.

[0037] In the lymphatic system examination device 1, the first light-emitting region 31 and the second light-emitting region 32 are arranged so that the closer they are to the imaging region R in the X direction, the farther they are from each other in the Y direction. This allows the excitation light to be more uniformly irradiated onto the lower body L of the subject S located in the imaging region R.

[0038] Furthermore, in the lymphatic system examination device 1, the illumination unit 3 and the imaging unit 4 are disposed on one side in the X direction of the imaging region R in which the lower body L of the subject S is located, and a restricting unit 26 disposed along the upper end Ra of the imaging region R restricts movement of the subject S to one side in the X direction. This makes it possible to maintain constant the distance between the illumination unit 3 and the lower body L of the subject S and the distance between the imaging unit 4 and the lower body L of the subject S, and to prevent the lower body L of the subject S from shaking. Therefore, the lymphatic system examination device 1 can acquire a fluorescent image of the lower body L appropriate for examining the lymphatic system of the lower body L of the subject S.

[0039] In the lymphatic system examination device 1, the restriction unit 26 extends in the Y direction, and the first plate 14 for brightness calibration is disposed on the surface 26a of the restriction unit 26 on the imaging unit 4 side. This allows the brightness of each acquired fluorescent image to be adjusted.

[0040] In the lymphatic system examination device 1, the restriction portion 26 extends in the Y direction, and the scale 15 is disposed on the surface 26a of the restriction portion 26 on the side of the imaging portion 4. This allows the size of each part of the lower body L to be ascertained from the acquired fluorescent image.

[0041] In the lymphatic system examination device 1, the second plate 16 for brightness calibration is placed on the main body 2 so that it is positioned in the imaging region R while contacting the restriction portion 26 from the side opposite to the imaging unit 4. This allows the brightness of the fluorescent image to be adjusted for each lymphatic system examination device 1.

[0042] In the lymphatic system examination device 1, a distance sensor 5 is disposed on one side in the X direction with respect to the imaging region R. This makes it possible to accurately grasp the position of the lower body L of the subject S in the X direction.

[0043] Furthermore, in the lymphatic system examination device 1 (and the lymphatic system examination method described above), at least one of the light emission time of the illumination unit 3 and the exposure time of the imaging unit 4 is changed, thereby generating multiple types of fluorescent images as fluorescent images of the lower body L of the subject S, and the multiple types of fluorescent images are displayed side by side. Although the intensity of the fluorescence changes depending on the state of the lymphatic system in the lower body L, the state of the lymphatic system in the lower body L can be appropriately grasped from the multiple types of fluorescent images generated and displayed as described above. Therefore, the lymphatic system examination device 1 (and the lymphatic system examination method described above) makes it possible to appropriately perform an examination of the lymphatic system in the lower body L of the subject S.

[0044] In the lymphatic system examination device 1, the control unit 11 generates each of the multiple types of fluorescent images in a time of 1 second or less, thereby making it possible to acquire the multiple types of fluorescent images while suppressing blurring of the lower body L of the subject S.

[0045] In the lymphatic system examination device 1, the control unit 11 controls the illumination unit 3 to emit the excitation light as a flash. This makes it possible to acquire multiple types of fluorescent images while suppressing changes in the amount of excitation light irradiated onto the lower body L of the subject S.

[0046] In the lymphatic system examination device 1, the control unit 11 stores previously generated fluorescent images of the lower body L of the subject S, and controls the display unit 12 to display previously generated fluorescent images of the lower body L and newly generated fluorescent images of the lower body L side by side. This makes it possible to appropriately grasp changes over time in the state of the lymphatic system in the lower body L of the subject S.

[0047] Furthermore, in the lymphatic system examination device 1, the placement unit 21 on which the subject S stands is provided with a positioning unit 8 that indicates the position at which the subject S is standing. This makes it possible to maintain a constant distance between the illumination unit 3 and the lower body L of the subject S and a constant distance between the imaging unit 4 and the lower body L of the subject S, and also makes it possible to align the orientation of both feet of the subject S with respect to the illumination unit 3 and the imaging unit 4 in a predetermined direction. Therefore, the lymphatic system examination device 1 can acquire a fluorescent image of the lower body L of the subject S that is appropriate for examining the lymphatic system in the lower body L.

[0048] In the lymphatic system examination device 1, the positioning unit 8 includes a foot print 81 when the subject S faces the imaging unit 4, and a foot print 82 when the subject S faces the opposite side of the imaging unit 4. This makes it possible to align the orientation of both feet of the subject S with respect to the illumination unit 3 and the imaging unit 4 in a predetermined direction when the subject S faces the imaging unit 4 and when the subject S faces the opposite side of the imaging unit 4.

[0049] In the lymphatic system examination device 1, a wall 25 constitutes a housing 250 that defines an imaging region R and houses the illumination unit 3 and the imaging unit 4, and an opening 25a inside which the subject S is placed is formed in the wall 25. This makes it possible to acquire a fluorescent image of the lower body L of the subject S while suppressing the effects of ambient light.

[0050] In the lymphatic system examination device 1, the cover 7 worn by the subject S covers the opening 25a. This makes it possible to obtain a fluorescent image of the lower body L of the subject S while more reliably suppressing the influence of ambient light.

[0051] In the lymphatic system inspection device 1, the support part 22 and the second wall part 252 are detachable from the mounting part 21 and the first wall part 251. This allows the portability of the lymphatic system inspection device 1 to be improved.

[0052] In the lymphatic system examination device 1, the camera 6 captures an image of the positioning unit 8. This allows the subject S to align his / her standing position with the positioning unit 8 while viewing the image captured by the camera 6, even when it is difficult for the subject S to directly view the positioning unit 8.

[0053] The present invention is not limited to the above-described embodiments. For example, as shown in Fig. 10, the surface 26b of the restricting unit 26 opposite the imaging unit 4 (see Fig. 3) may be a curved surface that curves to fit the lower abdomen of the subject S (i.e., concave toward the imaging unit 4). Furthermore, instead of or together with the foot impressions 81, 82, the positioning unit 8 may be a recessed or protruding portion provided on the placing surface 21a to fit the foot impression of the subject S. Furthermore, at least one of the illumination unit 3, the imaging unit 4, the distance sensor 5, the camera 6, and the restricting unit 26 may be attached to the frame 24 so as to enable at least one of position adjustment and angle adjustment. [Explanation of symbols]

[0054] 1...lymphatic system testing device, 2...main body, 3...illumination unit, 4...imaging unit, 5...distance sensor, 6...camera, 7...cover, 8...positioning unit, 11...control unit, 12...display unit, 14...first plate, 15...scale, 16...second plate, 21...placing unit, 22...support unit, 25...wall unit, 25a...opening, 26...regulating unit, 26a...surface, 31...first light-emitting area, 31a...first light-emitting portion, 32...second light-emitting area, 32a...second light-emitting portion, 81, 82...footprint, 250...housing, 251...first wall unit, 252...second wall unit, L...lower body, R...imaging area, Ra...upper end, S...subject.

Claims

1. a main body having a platform on which a subject whose lymphatic system has been injected with a fluorescent dye stands, the main body positioning the lower half of the subject's body in an imaging area on the platform; an illumination unit that irradiates the lower body with excitation light; an imaging unit that detects fluorescence emitted from the lower body in response to the irradiation of the excitation light; a first plate for brightness calibration; the illumination unit and the imaging unit are disposed on one side of the imaging area in a first horizontal direction, The main body portion further includes a restricting portion, the restricting unit is disposed along an upper end of the imaging area and restricts movement of the subject to the one side in the first horizontal direction; The lymphatic system examination device, wherein the first plate is disposed on a surface of the restriction portion on the imaging unit side, the restriction portion extending in a second horizontal direction perpendicular to the first horizontal direction.

2. The lymphatic system examination device according to claim 1 , further comprising: a scale disposed on a surface of the restriction portion, the surface extending in a second horizontal direction perpendicular to the first horizontal direction, on the imaging unit side.

3. a second plate for brightness calibration that is detachable from the main body; The lymphatic system examination device according to claim 1 , wherein the second plate is disposed in the main body so as to be positioned in the imaging area while contacting the restriction portion from the side opposite to the imaging portion.

4. The lymphatic system examination device according to claim 1 , further comprising a distance sensor disposed on the one side of the imaging region in the first horizontal direction, the distance sensor measuring a distance to the lower body located in the imaging region.

Images