Cartridge fixing structure and molecular diagnosis analyzer

Through the design of the card box fixed structure, the stable limit of the card box is used to achieve the stable limit of the card box, which solves the problem of the loosening of the kit box and affects the detection results, and improves the stability and accuracy of the detection results.

WO2025021042A1PCT designated stage expired Publication Date: 2025-01-30GUANGDONG RUNPENG BIOLOGICAL TECH CO LTD
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Patent Information

Application Number
PCT/CN2024/106511
Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
Priority Date
2023-07-21
Filing Date
2024-07-19
Publication Date
2025-01-30

AI Technical Summary

Technical Problem

In the prior art, the reagent cartridge is prone to loosening during use, and the connection method is not stable enough, which affects the detection results.

Method used

A card box fixed structure is designed, including the first fixed part, the first voltage part, the second pressure parts, the connected parts, and the supporting parts. Points to be connected to achieve limits and stable card boxes.

Benefits of technology

Effectively avoid loosening the card box during use, ensuring that the connection installation of the card box is more stable and reliable, and improves the accuracy of the test results.

✦ Generated by Eureka AI based on patent content.

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    Figure CN2024106511_30012025_PF_FP_ABST
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Abstract

Provided are a cartridge fixing structure and a molecular diagnosis analyzer, relating to the technical field of cartridge fixing. The cartridge fixing structure comprises a first fixing member, a first abutting member, a second abutting member, a linkage member and a bearing member, wherein the first fixing member is provided with a slot, which is configured to accommodate a cartridge; the first abutting member is movably arranged on the first fixing member, the second abutting member is movably arranged on the first fixing member, and the first abutting member and the second abutting member are respectively located on two sides of the slot; and the linkage member is connected to both the first abutting member and the second abutting member, and is configured to simultaneously drive the first abutting member and the second abutting member to move, such that the first abutting member and the second abutting member respectively abut against positioning points on the two sides of the cartridge so as to implement limiting, thus ensuring that the connection and installation of the cartridge are more stable and reliable.
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Description

A card box fixing structure and molecular diagnostic analyzer

[0001] CROSS-REFERENCE TO RELATED APPLICATIONS

[0002] This application claims priority to Chinese patent application number 202310906247.9, filed with the China Patent Office on July 21, 2023, entitled “A Cartridge Fixing Structure and Molecular Diagnostic Analyzer,” the entire contents of which are incorporated by reference into this application. Technical Field

[0003] The present disclosure relates to the technical field of cartridge fixing, and in particular to a cartridge fixing structure and a molecular diagnostic analyzer. Background Art

[0004] Nucleic acid extraction using centrifugal column or magnetic bead methods in biotechnology generally requires four steps: lysis, binding, washing, and elution, followed by subsequent steps such as nucleic acid hybridization, polymerase chain reaction, and molecular detection. Molecular detection technology is developing towards accuracy, convenience, sensitivity, automation, and integration. However, due to the inherent technical complexity of molecular detection, there are relatively few fully automated instrument platforms from sample to result. These fully automated instrument platforms are relatively complex in structure, and reagents are generally placed in reagent cartridges for various detection and extraction operations during nucleic acid extraction.

[0005] If the reagent cartridge becomes loose during use or the connection method of the cartridge is not stable enough, it will ultimately affect the test results.

[0006] Summary of the Invention

[0007] The present disclosure provides a cartridge fixing structure and a molecular diagnostic analyzer, which can make the cartridge connection more stable and reliable, and prevent the cartridge from becoming loose during use, thereby affecting the final detection result.

[0008] The embodiments of the present disclosure may be implemented as follows:

[0009] An embodiment of the present disclosure provides a card box fixing structure, which includes:

[0010] a first fixing member, the first fixing member being provided with a card slot, the card slot being configured to accommodate the card cartridge;

[0011] A first pressing member, the first pressing member is movably disposed on the first fixing member;

[0012] a second pressing member, the second pressing member being movably disposed on the first fixing member, and the first pressing member and the second pressing member being respectively located on two sides of the card slot;

[0013] A linkage member, the linkage member simultaneously connects the first pressing member and the second pressing member, and is configured to simultaneously drive the first pressing member and the second pressing member to move, so that the first pressing member and the second pressing member respectively abut against the positioning points on both sides of the card box, thereby achieving position limiting;

[0014] The supporting member is arranged below the card slot to be configured as a supporting card box.

[0015] Optionally, the first pressing member includes a first pushing member and a first side pressure rod, the first pushing member is rotatably connected to the first fixing member, and the first pushing member is connected to the linkage member, the first side pressure rod is connected to the first pushing member, and the first side pressure rod and the first fixing member are rotatably connected, and the first pushing member is configured to rotate relative to the first fixing member under the action of an external force, thereby driving the first side pressure rod to rotate relative to the first fixing member until the first side pressure rod abuts against the positioning point of the card box.

[0016] Optionally, the first side pressure rod includes a first connecting portion and a first pressing portion, the first connecting portion and the first pressing portion are connected, the middle portion of the first connecting portion is connected to the first pushing member, and an end of the first connecting portion away from the first pressing portion is hinged to the first fixing member, and the first pressing portion is configured to abut against the positioning point of the card box.

[0017] Optionally, the first connecting portion and the first pressing portion are both L-shaped.

[0018] Optionally, the first pushing member includes a first pushing rod and a first connecting rod, the first pushing rod and the first fixing member are rotatably connected, one end of the first pushing rod is connected to the linkage member, the other end of the first pushing rod is rotatably connected to the first connecting rod, and the first side pressure rod is connected to the first connecting rod.

[0019] Optionally, the first pressing member further includes a second side pressure rod, the second side pressure rod is connected to the first connecting rod, the second side pressure rod and the first fixing member are rotatably connected, and the second side pressure rod and the first side pressure rod are spaced apart.

[0020] Optionally, the card box fixing structure also includes a lock and a first elastic member. The first elastic member is arranged on the first fixing member. The first elastic member and the lock are in contact with each other. The lock is configured to be lockably connected to the linkage member under the elastic force of the first elastic member.

[0021] Optionally, the card box fixing structure also includes a reset elastic member, one end of the reset elastic member abuts against the first fixing member, and the other end of the reset elastic member is connected to the end of the first connecting rod away from the first push rod. When the lock is locked, the first connecting rod squeezes the reset elastic member so that the reset elastic member is in a compressed state. When the lock is unlocked, the first connecting rod is reset under the elastic force of the reset elastic member.

[0022] Optionally, the lock includes a buckle portion, a guide column and a pushing end, the guide column and the pushing end are respectively located on both sides of the buckle portion, and the guide column and the pushing end are both connected to the buckle portion, the first elastic member is sleeved on the guide column, and the linkage member is provided with a buckle groove, the inner wall of the buckle groove abuts against the buckle portion, and the buckle portion and the linkage member can be locked and connected.

[0023] Optionally, the first fixing member includes a left first fixing member and a right first fixing member, and the left first fixing member and the right first fixing member are connected to define a card slot.

[0024] Optionally, a sliding groove is provided on the edge of the card slot, the sliding groove is connected to the card slot, and the sliding groove is configured to limit the side wall of the card box.

[0025] Optionally, the supporting member includes a bottom plate and a second fixing member, the second fixing member is arranged below the card slot, the first fixing member and the second fixing member are both arranged on the bottom plate, and the second fixing member is configured to support the card box.

[0026] Optionally, the second fixing member includes an accommodating portion and a second elastic member, and the second elastic member is arranged below the accommodating portion. When the card box is inserted into the card slot and pressure is applied to the accommodating portion, the second elastic member connected to the accommodating portion is compressed so that the card box can be elastically engaged and fixed.

[0027] Optionally, the upper part of the accommodating portion has an accommodating groove, the lower part of the accommodating portion has a guide rod, the second elastic member is sleeved on the outer circumference of the guide rod, and a through hole is opened on the bottom plate. The guide rod can be slidably accommodated in the through hole, so that the accommodating portion can move up and down along the setting direction of the guide rod, thereby causing the second elastic member to be compressed or restored.

[0028] Optionally, the receiving portion includes a heating component, and the heating component is configured to control the temperature of the card box located in the receiving portion.

[0029] Optionally, the cartridge includes a sample chamber and an elution chamber, and the second fixing member is disposed below both the sample chamber and the elution chamber, and is configured to perform temperature control on the sample chamber and the elution chamber.

[0030] The present disclosure also provides another card box fixing structure, which includes:

[0031] a first fixing member, the first fixing member being provided with a card slot, the card slot being configured to accommodate the card cartridge;

[0032] A first pressing member, the first pressing member is movably disposed on the first fixing member;

[0033] a second pressing member, the second pressing member being movably disposed on the first fixing member, and the first pressing member and the second pressing member being respectively located on both sides of the card slot; the first pressing member and the second pressing member being configured to abut against positioning points on both sides of the card box, respectively, thereby achieving position limiting; and

[0034] The supporting member includes two second fixing members, both of which are arranged below the card slot, and the two second fixing members are configured to jointly support the card box placed in the card slot.

[0035] An embodiment of the present disclosure further provides a molecular diagnostic analyzer comprising any of the above described cartridge fixing structures.

[0036] The beneficial effects of the cartridge fixing structure and molecular diagnostic analyzer of the disclosed embodiments include, for example:

[0037] The card box fixing structure includes a first fixing member, a first pressing member, a second pressing member, a linkage member and a supporting member. The first fixing member is provided with a card slot, and the card slot is configured to accommodate the card box. The first pressing member is movably arranged on the first fixing member, and the second pressing member is movably arranged on the first fixing member, and the first pressing member and the second pressing member are respectively located on both sides of the card slot. The linkage member connects the first pressing member and the second pressing member at the same time, and the linkage member is configured to simultaneously drive the first pressing member and the second pressing member to move, so that the first pressing member and the second pressing member respectively abut against the positioning points on both sides of the card box, thereby realizing limiting. The supporting member is arranged below the card slot to be configured to support the card box. When the card box fixing structure is in use, the card slot of the first fixing part can accommodate the card box, the card box is placed in the card slot, the supporting part supports the card box, and the linkage part simultaneously drives the first pressing part and the second pressing part to move, so that the first pressing part and the second pressing part respectively abut against the positioning points on both sides of the card box, thereby fixing the card box in the card slot, realizing the limiting function, ensuring that the connection and installation of the card box are more stable and reliable, and avoiding the card box from loosening during use, thereby affecting the final detection result.

[0038] The molecular diagnostic analyzer includes the above-mentioned cartridge fixing structure, and accordingly has the technical effect of the cartridge fixing structure. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] In order to more clearly illustrate the technical solutions of the embodiments of the present disclosure, the following briefly introduces the drawings required for use in the embodiments. It should be understood that the following drawings only illustrate certain embodiments of the present disclosure and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other relevant drawings can be obtained based on these drawings without any creative work.

[0040] FIG1 is a schematic structural diagram of a card box fixing structure provided by this embodiment from a first perspective;

[0041] FIG2 is a structural diagram of a card box fixing structure provided by this embodiment from a second perspective;

[0042] FIG3 is a schematic structural diagram of a card box fixing structure provided by this embodiment from a third perspective;

[0043] FIG4 is a schematic structural diagram of a card box fixing structure provided by this embodiment from a fourth perspective;

[0044] FIG5 is a schematic structural diagram of a card box fixing structure provided by this embodiment from a fifth perspective;

[0045] FIG6 is a schematic structural diagram of the second fixing member provided in this embodiment.

[0046] Icons: 10-first fixing member; 11-left fixing member; 12-right fixing member; 20-first pressing member; 21-first push rod; 22-first side pressure rod; 221-first connecting portion; 222-first pressing portion; 23-first connecting rod; 24-second side pressure rod; 241-second connecting portion; 242-second pressing portion; 30-second pressing member; 40-linkage member; 41-snap-on groove; 50-lock; 51-snap-on portion; 52-guide column; 53-pushing end; 60-first elastic member; 70-locking pressure plate; 101-card slot; 80-second fixing member; 81-accommodating portion; 811-accommodating groove; 812-guide rod; 82-second elastic member; 90-bottom plate; 100-card box fixing structure. DETAILED DESCRIPTION

[0047] To make the objectives, technical solutions, and advantages of the embodiments of the present disclosure more clear, the technical solutions of the embodiments of the present disclosure will be clearly and completely described below in conjunction with the accompanying drawings of the embodiments of the present disclosure. Obviously, the described embodiments are only some of the embodiments of the present disclosure, but not all of them. Generally, the components of the embodiments of the present disclosure described and shown in the drawings herein can be arranged and designed in various different configurations.

[0048] Therefore, the following detailed description of the embodiments of the present disclosure provided in the accompanying drawings is not intended to limit the scope of the present disclosure as claimed, but merely represents selected embodiments of the present disclosure. All other embodiments obtained by ordinary technicians in this field based on the embodiments of the present disclosure without making any creative efforts shall fall within the scope of protection of the present disclosure.

[0049] It should be noted that similar reference numerals and letters denote similar items in the following drawings, and therefore, once an item is defined in one drawing, it does not need to be further defined or explained in subsequent drawings.

[0050] In the description of the present disclosure, it should be noted that if the terms "upper", "lower", "inside", "outside", etc. appear, the orientation or position relationship indicated is based on the orientation or position relationship shown in the accompanying drawings, or is the orientation or position relationship in which the invented product is usually placed when used. It is only for the convenience of describing the present disclosure and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, it cannot be understood as a limitation on the present disclosure.

[0051] In addition, the terms "first", "second", etc., if used, are merely used to distinguish and describe, and should not be understood as indicating or implying relative importance.

[0052] It should be noted that, in the absence of conflict, the features in the embodiments of the present disclosure may be combined with each other.

[0053] Nucleic acid extraction using centrifugal column or magnetic bead methods in biotechnology generally requires four steps: lysis, binding, washing, and elution, followed by subsequent steps such as nucleic acid hybridization, polymerase chain reaction, and molecular detection. Molecular detection technology is developing towards accuracy, convenience, sensitivity, automation, and integration. However, due to the inherent technical complexity of molecular detection, there are relatively few fully automated instrument platforms from sample to result. These fully automated instrument platforms are relatively complex in structure, and reagents are generally placed in reagent cartridges for various detection and extraction operations during nucleic acid extraction.

[0054] If the reagent cartridge becomes loose during use or the connection method of the cartridge is not stable enough, it will ultimately affect the test results.

[0055] To address the aforementioned issues, referring to Figures 1-6 , this embodiment provides a molecular diagnostic analyzer comprising a cartridge securing structure 100. This molecular diagnostic analyzer effectively addresses the aforementioned technical issues, enabling a more stable and reliable cartridge connection, preventing the cartridge from loosening during use and potentially affecting the final test results.

[0056] Please refer to Figures 1 to 4. The card box fixing structure 100 includes a first fixing member 10, a first pressing member 20, a second pressing member 30, a linkage member 40 and a supporting member. The first fixing member 10 is provided with a card slot 101, and the card slot 101 is configured to accommodate the card box. The first pressing member 20 is movably arranged on the first fixing member 10, and the second pressing member 30 is movably arranged on the first fixing member 10, and the first pressing member 20 and the second pressing member 30 are respectively located on both sides of the card slot 101. The linkage member 40 connects the first pressing member 20 and the second pressing member 30 at the same time. The linkage member 40 is configured to simultaneously drive the first pressing member 20 and the second pressing member 30 to move, so that the first pressing member 20 and the second pressing member 30 respectively abut against the positioning points on both sides of the card box, thereby realizing limiting. The supporting member is arranged below the card slot 101 to be configured to support the card box.

[0057] In this embodiment, the first fixing member 10 includes a left fixing member 11 and a right fixing member 12, which are connected to define a slot 101. The left fixing member 11 and the right fixing member 12 are connected to form the first fixing member 10, which facilitates assembly and maintenance of internal components and disassembly.

[0058] Optionally, the number of the left fixing members 11 is two, and the two left fixing members 11 are respectively arranged on both sides of the right fixing member 12 .

[0059] Among them, the left fixing part 11 and the right fixing part 12 are both block-shaped structural parts, and end plates are provided at both ends of the right fixing part 12. The middle part of the end plate is fixedly connected to the right fixing part 12, and the end plate is vertically arranged to the right fixing part 12. The edge of the end plate is connected to the left fixing part 11, so that there is a gap between the left fixing part 11 and the right fixing part 12, thereby forming a card slot 101.

[0060] More preferably, a slide groove is provided on the edge of the card slot 101, the slide groove being connected to the card slot 101 and configured to limit the sidewalls of the card box. Optionally, a stopper is provided on both sides of the card box, the position of the stopper being adapted to the position of the slide groove. When the card box is placed in the card slot 101, the stopper is located in the slide groove, thereby limiting the card box and restricting its horizontal movement.

[0061] In order to improve the problem that the card box is easy to loosen and the connection method of the card box is not stable and reliable enough, which affects the reagent detection results, the card box fixing structure 100 provided in this embodiment is used. During use, the card box is first placed in the card slot 101 of the first fixing member 10, and then the first pressing member 20 and the second pressing member 30 are moved simultaneously through the linkage member 40, so that the first pressing member 20 and the second pressing member 30 are respectively abutted against the positioning points on the side of the card box. The first pressing member 20 and the second pressing member 30 can jointly limit the card box, that is, the positioning points of the card box can be quickly and accurately fixed and limited, so that the card box can be stably set in the card slot 101.

[0062] In this embodiment, the card case has a rectangular parallelepiped structure, with two positioning points provided on each side of the card case. The first pressing member 20 simultaneously abuts the two positioning points on one side of the card case, and the second pressing member 30 simultaneously abuts the two positioning points on the other side of the card case, thereby achieving an optimal positioning effect and ensuring the stability of the card case connection and installation. In other embodiments, the number of positioning points on both sides of the card case may be increased or decreased, and this is not specifically limited here.

[0063] Optionally, in order to facilitate the removal of the card cartridge placed in the card slot 101 , a notch is provided on the edge of the card slot 101 . The notch can facilitate the operator to remove the card cartridge in the card slot 101 , thereby achieving quick and stable removal.

[0064] Optionally, there may be multiple notches, and all of the notches are connected to the card slot 101. The notches in this embodiment are square in structure.

[0065] In this embodiment, the first pressing member 20 includes a first pushing member and a first side pressure rod 22. The first pushing member is rotatably connected to the first fixing member 10, and the first pushing member is connected to the linkage member 40. The first side pressure rod 22 is connected to the first pushing member, and the first side pressure rod 22 and the first fixing member 10 are rotatably connected. The first pushing member is configured to rotate relative to the first fixing member 10 under the action of an external force, thereby driving the first side pressure rod 22 to rotate relative to the first fixing member 10 until the first side pressure rod 22 abuts against the positioning point of the card box.

[0066] Optionally, the first pushing member includes a first push rod 21 and a first connecting rod 23, the first push rod 21 is rotatably connected to the first fixing member 10, one end of the first push rod 21 is connected to the linkage member 40, the other end of the first push rod 21 is rotatably connected to the first connecting rod 23, and the first side pressure rod 22 is connected to the first connecting rod 23.

[0067] In this embodiment, the first push rod 21 is formed by welding two strip rods, which are arranged at an obtuse angle. The end of one strip rod is connected to the linkage member 40, and the end of the other strip rod is connected to the first connecting rod 23.

[0068] More preferably, the first connecting rod 23 is a long rod structure.

[0069] In this embodiment, the first pressure member 20 includes a first push rod 21, a first side pressure rod 22 and a first connecting rod 23. The first push rod 21 is rotatably connected to the first fixing member 10. One end of the first push rod 21 is connected to the linkage member 40, and the other end of the first push rod 21 is rotatably connected to the first connecting rod 23. The first side pressure rod 22 is connected to the first connecting rod 23, and the first side pressure rod 22 is rotatably connected to the first fixing member 10. The first push rod 21 is configured to rotate relative to the first fixing member 10 under the action of external force, thereby driving the first connecting rod 23 to move, and then the first side pressure rod 22 is driven by the first connecting rod 23 to rotate relative to the first fixing member 10 until the first side pressure rod 22 abuts against the positioning point of the card box.

[0070] It should be noted that the first push rod 21, the first connecting rod 23 and the first side pressure rod 22 together constitute a connecting rod structure, one end of the first connecting rod 23 is hinged to the first push rod 21, the first connecting rod 23 and the first side pressure rod 22 are hinged, the first push rod 21 and the first fixing member 10 are hinged, and the first push rod 21 rotates around the hinge point relative to the first fixing member 10 under the action of external force, and the first connecting rod 23 rotates under the push of the first push rod 21, thereby driving the first side pressure rod 22 to rotate, and finally abutting against the positioning point on the side of the card box.

[0071] Optionally, the first side pressure rod 22 includes a first connecting portion 221 and a first pressing portion 222, the first connecting portion 221 and the first pressing portion 222 are connected, the middle part of the first connecting portion 221 is connected to the connecting rod, and the end of the first connecting portion 221 away from the first pressing portion 222 is hinged to the first fixing member 10, and the first pressing portion 222 is configured to abut against the positioning point of the card box.

[0072] It can be understood that the structure of the contact surface of the first pressing portion 222 contacting the positioning point of the cartridge is adapted to the structure of the positioning point.

[0073] In this embodiment, the first connecting portion 221 and the first pressing portion 222 are both L-shaped.

[0074] Optionally, the first connecting portion 221 rotates along with the first connecting rod 23 , and the first pressing portion 222 rotates counterclockwise to press downwards against a positioning point on the side of the card box, thereby achieving position limiting.

[0075] It should be noted that the first pressing member 20 further includes a second side pressure rod 24, which is connected to the first connecting rod 23 and rotatably connected to the first fixing member 10. The second side pressure rod 24 is spaced apart from the first side pressure rod 22. The first side pressure rod 22 and the second side pressure rod 24 are respectively configured to abut different positioning points on the same side of the cartridge.

[0076] It can be understood that the second side pressure rod 24 includes a second connecting portion 241 and a second pressing portion 242, the second connecting portion 241 and the second pressing portion 242 are connected, the middle part of the second connecting portion 241 is connected to the connecting rod, and the end of the second connecting portion 241 away from the second pressing portion 242 is hinged to the first fixing member 10, and the second pressing portion 242 is configured to abut against the positioning point of the card box.

[0077] Optionally, the second push rod, the second connecting rod and the second side pressure rod 24 together form a connecting rod structure, one end of the second connecting rod is hinged to the second push rod, the second connecting rod is hinged to the second side pressure rod 24, the second push rod and the first fixing member 10 are hinged, and the second push rod rotates around the hinge point relative to the first fixing member 10 under the action of external force, and the second connecting rod rotates under the push of the second push rod, thereby driving the second side pressure rod 24 to rotate, and finally abutting against the positioning point on the side of the card box.

[0078] In this embodiment, the linkage member 40 is a rod-shaped structure, and a plurality of connecting holes are provided on the linkage member 40. The ends of the first push rod 21 and the second push rod are respectively arranged in different connecting holes, so that the connecting rod can simultaneously drive the first push rod 21 and the second push rod to move when moving.

[0079] In this embodiment, both the first pressing member 20 and the second pressing member 30 move in the card slot 101 , thereby achieving contact or release with the positioning points on the side of the card box.

[0080] It should also be noted that, in order to ensure the stability of the position between the first pressing member 20 and the second pressing member 30 and the positioning points on the side of the cartridge, the cartridge fixing structure 100 further includes a lock 50 and a first elastic member 60. The first elastic member 60 is provided on the first fixing member 10, and the first elastic member 60 abuts against the lock 50. The lock 50 is configured to be lockably connected to the linkage member 40 under the elastic force of the first elastic member 60. In the case where the first pressing member 20 and the second pressing member 30 abut against the positioning points on the side of the cartridge respectively, the lock 50 locks the linkage member 40 to ensure the stability of the abutment. After the lock 50 and the linkage member 40 are unlocked, the linkage member 40 can drive the first pressing member 20 and the second pressing member 30 to separate from the positioning points on the side of the cartridge, thereby releasing the position limit on the cartridge.

[0081] A groove is formed on the side of the first fixing member 10 , and the first elastic member 60 is disposed in the groove, with one end of the first elastic member 60 abutting against the wall of the groove, and the other end of the first elastic member 60 abutting against the lock buckle 50 .

[0082] Optionally, the lock 50 includes a buckle portion 51, a guide column 52 and a pushing end 53, the guide column 52 and the pushing end 53 are respectively located on both sides of the buckle portion 51, and the guide column 52 and the pushing end 53 are both connected to the buckle portion 51, the first elastic member 60 is sleeved on the guide column 52, and the buckle portion 51 and the linkage member 40 can be locked and connected.

[0083] During operation, the first elastic member 60 is sleeved on the guide column 52, one end of the first elastic member 60 abuts against the wall of the groove, and the other end of the first elastic member 60 abuts against the wall of the buckling portion 51. The guide column 52 is movably arranged in the groove, and the guide column 52 is configured to limit the movement direction of the first elastic member 60. The buckling portion 51 and the linkage member 40 are buckled together to lock the linkage member 40. When the buckling portion 51 and the linkage member 40 need to be unlocked, the pushing end 53 is pressed so that the wall of the buckling portion 51 squeezes the first elastic member 60 and moves until the buckling portion 51 and the linkage member 40 are separated, and unlocking is achieved.

[0084] More preferably, the linkage member 40 is provided with a buckle groove 41, the inner wall of the buckle groove 41 abuts against the buckle portion 51 to achieve locking of the buckle portion 51 and the linkage member 40. The buckle portion 51 is provided with a buckle, the bottom of the buckle abuts against the inner wall of the buckle groove 41, thereby achieving locking of the buckle portion 51 and the linkage member 40.

[0085] In addition, the card box fixing structure 100 further includes a locking pressure plate 70 , which is disposed on the top surface of the lock 50 and is connected to the lock 50 and the side wall of the first fixing member 10 .

[0086] In this embodiment, there are two locking pressure plates 70, which are respectively connected to the two ends of the buckle part 51 and are configured to limit the movement of the buckle part 51. The locking pressure plates 70 can prevent the guide column 52 from popping out of the groove, thereby limiting the movement of the lock 50.

[0087] In this embodiment, the first elastic member 60 is a spring.

[0088] It should also be explained that, in order to facilitate the removal of the card box, the card box fixing structure 100 also includes a reset elastic member, one end of the reset elastic member abuts against the first fixing member 10, and the other end of the reset elastic member is connected to the end of the first connecting rod 23 away from the first push rod 21. When the lock 50 is locked, the first connecting rod 23 squeezes the reset elastic member so that the reset elastic member is in a compressed state. When the lock 50 is unlocked, the first connecting rod 23 is reset under the elastic force of the reset elastic member, thereby realizing rapid unlocking of the card box.

[0089] Optionally, the reset elastic member is a spring. When the first side pressure rod 22 and the second side pressure rod 24 abut the positioning point, the springs connected to the ends of the first connecting rod 23 and the second connecting rod are in a compressed state. After unlocking the linkage member 40, the first connecting rod 23 and the second connecting rod can move quickly under the elastic force of the spring, thereby driving the first side pressure rod 22 and the second side pressure rod 24 away from the positioning point.

[0090] Please refer to Figures 5 and 6. In this embodiment, the supporting member includes a second fixing member 80 and a base plate 90. The second fixing member 80 is arranged on the base plate 90, wherein the second fixing member 80 is arranged at the lower part of the card slot 101. The second fixing member 80 has a structure that is adapted to the lower part of the card box, so that when the card box is placed in the card slot 101, the second fixing member 80 can contact and cooperate with the adaptation structure to support the card box.

[0091] Optionally, the supporting member includes two second fixing members 80, both of which are disposed on the bottom plate 90 and below the card slot 101. The two second fixing members 80 are configured to jointly support the card cartridge placed in the card slot 101. In this way, the stability of the card cartridge placed in the card slot 101 can be ensured.

[0092] Optionally, the second fixing member 80 includes a accommodating portion 81 and a second elastic member 82, wherein the accommodating portion 81 is configured to accommodate part of the structure at the bottom of the card box when the card box is placed in the card slot 101 to support it, and the second elastic member 82 is arranged below the accommodating portion 81. When the card box applies pressure to the accommodating portion 81 along the insertion direction, the second elastic member 82 connected to the accommodating portion 81 is compressed so that the card box can be elastically fixed in an engageable manner.

[0093] It should be noted that an accommodating groove 811 is provided at the upper part of the accommodating portion 81, and a guide rod 812 is provided at the lower part of the accommodating portion 81. The second elastic member 82 can be a spring, which is sleeved on the outer periphery of the guide rod 812. A through hole adapted to the guide rod 812 is opened on the bottom plate 90, and the guide rod 812 can be slidably accommodated in the through hole so that the accommodating portion 81 can move up and down along the direction of the guide rod 812, and the second elastic member 82 is compressed or restored.

[0094] In other embodiments, the accommodating portion 81 further includes a heating component, which is configured to abut and heat the card box in the accommodating portion 81. Optionally, the heating component includes a heating element, a heat conductor, and a heat insulating member; wherein the heating element is configured to heat the portion of the card box located in the accommodating portion 81 to promote the biochemical reaction in the card box; one side of the heat conductor abuts the heating element, and the other side is configured as a accommodating groove 811, which is configured to heat the accommodated card box, and the heat insulating member can be provided with heat-insulating cotton in the portion where the heat conductor and the heating element are in contact with the outside world to reduce heat dissipation. A second fixing member 80 is provided at the bottom of the card slot 101, and the accommodating portion 81 of the second fixing member 80 and the second elastic member 82 are configured to fully abut the lower portion of the card box, so that the thermal contact between the heat conductor and the card box is closer, thereby improving the heating efficiency.

[0095] In other embodiments, the cartridge comprises a sample chamber and an elution chamber, and can be used for nucleic acid extraction and testing of biological samples. Optionally, the sample chamber is used to lyse the biological sample and release nucleic acids, while the elution chamber is used to provide a physical and chemical environment for eluting nucleic acids from the stationary phase. Because both require a certain temperature, the second fixture 80 can be disposed below the sample chamber and the elution chamber, respectively.

[0096] In summary, the embodiment of the present disclosure provides a cartridge fixing structure 100 and a molecular diagnostic analyzer, wherein the cartridge fixing structure 100 includes a first fixing member 10, a first pressing member 20, a second pressing member 30 and a linkage member 40. The first fixing member 10 is provided with a card slot 101, and the card slot 101 is configured to accommodate the cartridge. The first pressing member 20 is movably arranged on the first fixing member 10, and the second pressing member 30 is movably arranged on the first fixing member 10, and the first pressing member 20 and the second pressing member 30 are respectively located on both sides of the card slot 101, and the linkage member 40 simultaneously connects the first pressing member 20 and the second pressing member 30, and the linkage member 40 is configured to simultaneously drive the first pressing member 20 and the second pressing member 30 to move, so that the first pressing member 20 and the second pressing member 30 respectively abut against the positioning points on both sides of the cartridge, thereby realizing positioning limitation. When the card box fixing structure 100 is in use, the card slot 101 of the first fixing member 10 can accommodate the card box, and the card box is placed in the card slot 101. The linkage member 40 simultaneously drives the first pressing member 20 and the second pressing member 30 to move, so that the first pressing member 20 and the second pressing member 30 respectively abut against the positioning points on both sides of the card box, thereby fixing the card box in the card slot 101, realizing the limiting function, ensuring that the connection and installation of the card box is more stable and reliable, and avoiding the card box from loosening during use, thereby affecting the final detection result.

[0097] The molecular diagnostic analyzer includes the above-mentioned cartridge fixing structure 100 and correspondingly has the technical effects of the cartridge fixing structure 100 .

[0098] The above description is merely a specific embodiment of the present disclosure, but the scope of protection of the present disclosure is not limited thereto. Any changes or substitutions that can be easily conceived by a person skilled in the art within the technical scope disclosed in this disclosure should be included in the scope of protection of the present disclosure. Therefore, the scope of protection of the present disclosure should be based on the scope of protection of the claims. Industrial Applicability

[0099] When the cartridge fixing structure of the molecular diagnostic analyzer disclosed herein is in use, the slot of the first fixing member can accommodate the cartridge, the cartridge is placed in the slot, the supporting member supports the cartridge, and the linkage member simultaneously drives the first pressing member and the second pressing member to move, so that the first pressing member and the second pressing member respectively abut against the positioning points on both sides of the cartridge, thereby fixing the cartridge in the slot, achieving a limiting effect, ensuring that the connection and installation of the cartridge are more stable and reliable, and preventing the cartridge from loosening during use, thereby affecting the final detection result.

Claims

1. A card box fixing structure, characterized in that: include: A first fixing member (10), wherein the first fixing member (10) is provided with a card slot (101), and the card slot (101) is configured to accommodate a card box; A first pressing member (20), wherein the first pressing member (20) is movably disposed on the first fixing member (10); a second pressing member (30), wherein the second pressing member (30) is movably disposed on the first fixing member (10), and the first pressing member (20) and the second pressing member (30) are respectively located on two sides of the card slot (101); A linkage member (40), wherein the linkage member (40) is connected to the first pressing member (20) and the second pressing member (30) at the same time, and the linkage member (40) is configured to simultaneously drive the first pressing member (20) and the second pressing member (30) to move, so that the first pressing member (20) and the second pressing member (30) are respectively in contact with the positioning points on both sides of the card box, thereby achieving position limiting; A supporting member is arranged below the card slot (101) so as to be configured to support a card box.

2. The card box fixing structure according to claim 1, characterized in that: The first pressing member (20) includes a first pushing member and a first side pressure rod (22), the first pushing member is rotatably connected to the first fixing member (10), and the first pushing member is connected to the linkage member (40), the first side pressure rod (22) is connected to the first pushing member, and the first side pressure rod (22) and the first fixing member (10) are rotatably connected, the first pushing member is configured to rotate relative to the first fixing member (10) under the action of an external force, thereby driving the first side pressure rod (22) to rotate relative to the first fixing member (10) until the first side pressure rod (22) abuts against a positioning point of the card box.

3. The card box fixing structure according to claim 2, characterized in that: The first side pressure rod (22) includes a first connecting portion (221) and a first pressing portion (222), the first connecting portion (221) and the first pressing portion (222) are connected, the middle portion of the first connecting portion (221) is connected to the first pushing member, one end of the first connecting portion (221) away from the first pressing portion (222) is hinged to the first fixing member (10), and the first pressing portion (222) is configured to abut against a positioning point of the card box.

4. The card box fixing structure according to claim 3, characterized in that: The first connecting portion (221) and the first pressing portion (222) are both L-shaped.

5. The card box fixing structure according to any one of claims 2 to 4, characterized in that: The first pushing member includes a first pushing rod (21) and a first connecting rod (23); the first pushing rod (21) and the first fixing member (10) are rotatably connected; one end of the first pushing rod (21) is connected to the linkage member (40); the other end of the first pushing rod (21) is rotatably connected to the first connecting rod (23); and the first side pressure rod (22) is connected to the first connecting rod (23).

6. The card box fixing structure according to claim 5, characterized in that: The first pressing member (20) further comprises a second side pressure rod (24), the second side pressure rod (24) being connected to the first connecting rod (23), the second side pressure rod (24) being rotatably connected to the first fixing member (10), and the second side pressure rod (24) and the first side pressure rod (22) being spaced apart.

7. The card box fixing structure according to claim 5, characterized in that: The card box fixing structure (100) also includes a lock (50) and a first elastic member (60), wherein the first elastic member (60) is arranged on the first fixing member (10), the first elastic member (60) and the lock (50) are in abutment with each other, and the lock (50) is configured to be lockably connected to the linkage member (40) under the elastic force of the first elastic member (60).

8. The card box fixing structure according to claim 7, characterized in that: The card box fixing structure (100) also includes a reset elastic member, one end of the reset elastic member is in contact with the first fixing member (10), and the other end of the reset elastic member is connected to an end of the first connecting rod (23) away from the first push rod (21). When the lock catch (50) is locked, the first connecting rod (23) squeezes the reset elastic member so that the reset elastic member is in a compressed state. When the lock catch (50) is unlocked, the first connecting rod (23) is reset under the elastic force of the reset elastic member.

9. The card box fixing structure according to claim 7 or 8, characterized in that: The lock buckle (50) comprises a buckling portion (51), a guide column (52) and a pushing end (53), wherein the guide column (52) and the pushing end (53) are respectively located on both sides of the buckling portion (51), and the guide column (52) and the pushing end (53) are both connected to the buckling portion (51), the first elastic member (60) is sleeved on the guide column (52), the linkage member (40) is provided with a buckling groove (41), the inner wall of the buckling groove (41) is in abutment with the buckling portion (51), and the buckling portion (51) and the linkage member (40) are lockably connected.

10. The card box fixing structure according to any one of claims 1 to 9, characterized in that: The first fixing member (10) comprises a left fixing member (11) and a right fixing member (12), and the left fixing member (11) and the right fixing member (12) are connected to define the card slot (101).

11. The card box fixing structure according to any one of claims 1 to 10, characterized in that: A slide groove is provided on the edge of the card slot (101), the slide groove is in communication with the card slot (101), and the slide groove is configured to limit the side wall of the card box.

12. The card box fixing structure according to any one of claims 1 to 11, characterized in that: The supporting member comprises a bottom plate (90) and a second fixing member (80), wherein the second fixing member (80) is arranged below the card slot (101), the first fixing member (10) and the second fixing member (80) are both arranged on the bottom plate (90), and the second fixing member (80) is configured to support a card box.

13. The card box fixing structure according to claim 12, characterized in that: The second fixing member (80) includes a receiving portion (81) and a second elastic member (82), wherein the second elastic member (82) is arranged below the receiving portion (81), and when the card box is inserted into the card slot (101) and pressure is applied to the receiving portion (81), the second elastic member (82) connected to the receiving portion (81) is compressed so that the card box can be elastically engaged and fixed.

14. The card box fixing structure according to claim 13, characterized in that: The upper portion of the accommodating portion (81) has an accommodating groove (811), the lower portion of the accommodating portion (81) has a guide rod (812), the second elastic member (82) is sleeved on the outer periphery of the guide rod (812), the bottom plate (90) is provided with a through hole, the guide rod (812) can be slidably accommodated in the through hole, so that the accommodating portion (81) can move up and down along the setting direction of the guide rod (812), so that the second elastic member (82) is compressed or restored.

15. The card box fixing structure according to claim 13 or 14, characterized in that: The receiving portion (81) comprises a heating component, and the heating component is configured to control the temperature of the card box located in the receiving portion (81).

16. The card box fixing structure according to claim 15, characterized in that: The card box comprises a sample chamber and an elution chamber, and the second fixing member (80) is arranged under the sample chamber and the elution chamber at the same time, and is configured to control the temperature of the sample chamber and the elution chamber.

17. A card box fixing structure, characterized in that: include: A first fixing member (10), wherein the first fixing member (10) is provided with a card slot (101), and the card slot (101) is configured to accommodate a card box; A first pressing member (20), wherein the first pressing member (20) is movably disposed on the first fixing member (10); a second pressing member (30), the second pressing member (30) being movably disposed on the first fixing member (10), and the first pressing member (20) and the second pressing member (30) being respectively located on two sides of the card slot (101); the first pressing member (20) and the second pressing member (30) being configured to be able to abut against positioning points on two sides of the card box respectively, thereby achieving position limiting; and, A supporting member, the supporting member comprising two second fixing members (80), the two second fixing members (80) are both arranged below the card slot (101), and the two second fixing members (80) are configured to jointly support a card box placed in the card slot (101).

18. A molecular diagnostic analyzer, characterized in that: It comprises the card box fixing structure (100) as described in any one of claims 1-17.

Citation Information

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