Cosmetic composition comprising galactomyces, having skin-soothing, moisture-retaining, skin tone-enhancing, and skin barrier-improving properties
The cosmetic composition addresses skin aging and barrier deterioration by incorporating Galactomyces and natural ingredients, enhancing skin health through soothing, moisture retention, and barrier improvement with minimal irritation.
Patent Information
- Application Number
- PCT/KR2024/013002
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2024-08-20
- Filing Date
- 2024-08-30
- Publication Date
- 2026-02-26
AI Technical Summary
Existing cosmetic products fail to effectively address skin aging, skin barrier deterioration, and skin irritation while being environmentally friendly and rich in natural ingredients.
A cosmetic composition containing Galactomyces fermentation filtrate, rice lees distillate, SH-oligopeptide-1, plant extract, skin conditioning agents, pH adjusting agents, surfactants, skin softeners, metal ion sequestering agents, film-forming agents, and thickeners, which are formulated to promote skin soothing, moisture retention, and skin barrier improvement, while preventing aging and damage.
The composition exhibits significant skin soothing, moisture retention, skin tone improvement, and skin barrier enhancement, with minimal irritation, and promotes skin cell regeneration, offering an environmentally friendly solution using upcycled rice lees and natural ingredients.
Abstract
Description
Cosmetic composition containing galactomyces for skin soothing, moisture retention, skin tone and skin barrier improvement
[0001] The present invention relates to a cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone and skin barrier improvement, and more specifically, to a cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone and skin barrier improvement, which contains a large amount of natural ingredients and thus causes less skin irritation, is environmentally friendly by upcycling rice lees, and is rich in Galactomyces, vitamins, minerals and organic acid ingredients, thereby exhibiting effects such as skin soothing, moisture retention, skin tone, skin barrier and skin tone improvement, and which prevents skin aging and skin damage and promotes skin cell regeneration to improve skin health.
[0002] The skin is the body's primary defense barrier and protects the body's organs from external environmental stimuli such as changes in temperature and humidity, ultraviolet rays, and pollutants.
[0003] However, as the human body ages, the secretion of various hormones that internally regulate metabolism decreases, and the function and activity of immune cells decline, which reduces the biosynthesis of immune proteins and biological components necessary for the body.
[0004] Additionally, externally, the skin's cleansing function is weakened and aging is accelerated due to physical and chemical stimulation and stress caused by increased ultraviolet rays, free radicals, and active oxygen due to environmental pollution such as ozone layer destruction.
[0005] In order to prevent this phenomenon and maintain healthier and more beautiful skin, efforts are being made to maintain the skin's natural functions and activate skin cells by adding physiologically active substances obtained from various known animals, plants, and microorganisms to cosmetics, thereby effectively inhibiting skin aging. In particular, many anti-aging and wrinkle-improving products using plant ingredients are being developed.
[0006] Recently, methods using fermented products of fermented strains have been attempted to improve skin health. Fermented products of fermented strains are known to have the function of activating natural moisturizing factors (NMF) to supply moisture to skin cells and help form a natural moisturizing barrier, the most representative of which is Galactomyces.
[0007] Galactomyces is one of the natural yeasts used for fermentation with nuruk. As it was discovered that the skin of the craftsmen who make nuruk in breweries is fine, clear, and elastic, interest in the effectiveness of Galactomyces fermentation, a natural yeast, and the various effective ingredients contained within it is increasing.
[0008] Meanwhile, efforts are being made to develop various cosmetics to improve phenomena such as collagen destruction, decreased collagen synthesis, loss of elastin, and melanin pigmentation due to deterioration of skin physiology, which occur in the skin epidermis and dermis.
[0009] The purpose of the present invention is to provide a cosmetic composition for skin soothing, moisture retention, skin tone and skin barrier improvement, which contains a large amount of natural ingredients, is environmentally friendly by upcycling rice lees, and contains abundant Galactomyces, vitamins, minerals and organic acid components, and exhibits effects such as skin soothing, moisture retention, skin tone, skin barrier and skin tone improvement, and prevents skin aging and skin damage and promotes skin cell regeneration to improve skin health.
[0010] The object of the present invention is achieved by providing a cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone and skin barrier improvement, characterized in that the cosmetic composition comprises Galactomyces fermentation filtrate, rice lees distillate, SH-oligopeptide-1, plant extract, skin conditioning agent, pH adjusting agent, surfactant, skin softener, metal ion sequestering agent, film forming agent and thickener.
[0011] According to a preferred feature of the present invention, the cosmetic composition for skin soothing, moisture retention, skin tone and skin barrier improvement containing Galactomyces comprises 100 parts by weight of Galactomyces fermentation filtrate, 10 to 30 parts by weight of rice lees distillate, 0.01 to 0.1 parts by weight of SH-oligopeptide-1, 0.1 to 1 parts by weight of plant extract, 1.5 to 2.5 parts by weight of skin conditioning agent, 0.1 to 0.5 parts by weight of pH adjusting agent, 0.5 to 1.5 parts by weight of surfactant, 4 to 6 parts by weight of skin softener, 0.04 to 0.06 parts by weight of metal ion sequestering agent, 0.1 to 0.3 parts by weight of film forming agent and 0.1 to 0.5 parts by weight of thickener, wherein the rice lees distillate comprises 100 parts by weight of Galactomyces fermentation filtrate, 10 to 30 parts by weight of rice lees distillate, 0.01 to 0.1 parts by weight of SH-oligopeptide-1, 0.1 to 1 part by weight of plant extract, 1.5 to 2.5 parts by weight of skin conditioning agent, 0.1 to 0.5 parts by weight of pH adjusting agent, 0.5 to 1.5 parts by weight of surfactant, 4 to 6 parts by weight of skin softener, 0.04 to 0.06 parts by weight of metal ion sequestering agent, 0.1 to 0.3 parts by weight of film forming agent and 0.1 to 0.5 parts by weight of thickener. A sterilized rice lees powder is prepared by mixing 10 to 50 parts by weight of sterilized rice lees powder and 1 to 5 parts by weight of alcohol, removing solids, and then distilling the mixture. The sterilized rice lees powder is prepared by sterilizing rice lees by heating at a temperature of 80 to 90°C for 20 to 40 minutes, and then drying and grinding the same. The alcohol is composed of at least one selected from the group consisting of butylene glycol, 1,2-hexanediol, and 1,3-propanediol. The plant extract is prepared by mixing aloe vera leaf extract, centella asiatica extract, licorice root extract, dandelion extract, safflower extract, ginkgo biloba extract, pomegranate extract, and mulberry bark extract in a weight ratio of 1:1:1:1:1:1:1:1.
[0012] According to a more preferred feature of the present invention, the cosmetic composition for skin soothing, moisture retention, skin tone and skin barrier improvement containing Galactomyces further contains 0.1 to 0.3 parts by weight of a water-soluble mineral and 0.01 to 0.1 parts by weight of a tissue regeneration agent per 100 parts by weight of the Galactomyces fermentation filtrate, wherein the water-soluble mineral is prepared by calcining coral or shells at a temperature of 850 to 950°C for 60 to 120 minutes and then powdering them into 800 to 1000 meshes, and the tissue regeneration agent is composed of at least one selected from the group consisting of polynucleotides, polydeoxyribonucleotides and hydrolyzed DNA.
[0013] The cosmetic composition for skin soothing, moisture retention, skin tone and skin barrier improvement containing Galactomyces according to the present invention contains a large amount of natural ingredients, so it causes little skin irritation, is environmentally friendly as it is made by upcycling rice lees, and contains abundant Galactomyces, vitamins, minerals and organic acid ingredients, so it exhibits effects such as skin soothing, moisture retention, skin tone, skin barrier and skin tone improvement, and exhibits an excellent effect of preventing skin aging and skin damage and promoting skin cell regeneration to improve skin health.
[0014] Hereinafter, preferred embodiments of the present invention and the properties of each component will be described in detail. However, this is intended to be a detailed description to enable a person having ordinary knowledge in the technical field to which the present invention pertains to easily carry out the invention, and does not mean that the technical idea and scope of the present invention are limited thereby.
[0015]
[0016] The cosmetic composition for skin soothing, moisture retention, skin tone and skin barrier improvement containing Galactomyces according to the present invention comprises Galactomyces fermentation filtrate, rice lees distillate, SH-oligopeptide-1, plant extract, skin conditioning agent, pH adjusting agent, surfactant, skin softener, metal ion sequestering agent, film forming agent and thickener, and comprises 100 parts by weight of Galactomyces fermentation filtrate, 10 to 30 parts by weight of rice lees distillate, 0.1 to 1 part by weight of SH-oligopeptide-1, 0.1 to 1 part by weight of plant extract, 1.5 to 2.5 parts by weight of skin conditioning agent, 0.1 to 0.5 parts by weight of pH adjusting agent, 0.5 to 1.5 parts by weight of surfactant, 4 to 6 parts by weight of skin softener, 0.04 to 0.5 parts by weight of metal ion sequestering agent. It is preferable that it consists of 0.06 parts by weight of a film-forming agent, 0.1 to 0.3 parts by weight of a film-forming agent, and 0.1 to 0.5 parts by weight of a thickener.
[0017]
[0018] The above Galactomyses Ferment Filtrate is a substance filtered after fermenting Galactomyces yeast, also known as Pitera, and is manufactured by inoculating Lactomyces with lactic acid bacteria, fermenting at a temperature of 20 to 40°C for 20 to 30 hours, and then subjecting the fermented product to a process of sterilization filtration after cell destruction, centrifugation, and membrane filtration.
[0019] At this time, the lactic acid bacteria may be Lactobacillus plantarum or Lactobacillus rhamnosus.
[0020] Galactomyces fermentation filtrate manufactured through the above process is rich in vitamins, minerals, amino acids, enzymes, organic acids, yeast peptides, etc., and is effective in removing dead skin cells and maintaining moisture, and not only improves skin texture, but also provides a skin whitening effect that improves skin elasticity and tone, and adjusts the skin's natural rhythm and balance to provide lively and healthy skin.
[0021] In addition, the particles are small and have good skin penetration, and they have a detoxifying function that breaks down toxic substances through the decomposition action of microorganisms. The lactic acid contained in Galatomyces shows low skin irritation while also showing an excellent removal effect on dead skin cells.
[0022]
[0023] The above rice lees distillate contains 10 to 30 parts by weight, and is manufactured through a process of mixing 100 parts by weight of Galactomyces fermentation filtrate, 10 to 50 parts by weight of sterilized rice lees powder, and 1 to 5 parts by weight of alcohol, removing solids, and then distilling. The rice lees distillate manufactured through the above process is rich in not only Galactomyces components but also amino acids and fatty acids, and has a detoxifying and moisturizing effect, and exhibits an environmentally friendly effect because it upcycles discarded rice lees.
[0024] The rice lees distillate manufactured through the above process is not only rich in vitamins, minerals, amino acids, enzymes, organic acids, and yeast peptides due to the use of Galactomyces fermentation filtrate, but also exhibits excellent skin improvement effects due to the extraction of various useful ingredients contained in the rice lees.
[0025] At this time, the sterilized rice lees powder is manufactured by heating the rice lees at a temperature of 80 to 90°C for 20 to 40 minutes to sterilize them, and then drying and grinding them. The drying is preferably performed by putting the sterilized rice lees into a drying device or the like so that the moisture content is 12% or less, and then grinding them into a particle size of 0.01 to 0.1 millimeters using a grinder.
[0026] The sterilized rice lees powder manufactured through the above process is mixed with the Galactomyces fermentation filtrate and alcohol component in a state where the fungi contained in the rice lees have been removed, and thus the effective ingredient contained in the rice lees powder has an improved elution efficiency, thereby acting as a skin conditioning agent that exhibits a skin improvement effect. However, if the content of the sterilized rice lees powder is less than 10 parts by weight, the above effect is minimal, and if the content of the sterilized rice lees powder exceeds 50 parts by weight, the distillation process cannot proceed properly, which is not preferable.
[0027] In addition, it is preferable that the alcohol is comprised of at least one selected from the group consisting of butylene glycol, 1,2-hexanediol and 1,3-propanediol, which are contained in an amount of 1 to 5 parts by weight and have a mass concentration of 60 to 80%, and which not only improves the elution efficiency of the effective ingredient contained in the sterilized rice lees powder, but also plays a role in improving the preservation property by inhibiting deterioration of the cosmetic composition manufactured through the present invention.
[0028] If the content of the alcohol is less than 1 part by weight, the above effect is minimal, and if the content of the alcohol exceeds 5 parts by weight, the above effect is not significantly improved, and the skin irritation of the cosmetic composition manufactured through the present invention may increase, which is not preferable.
[0029] In addition, if the content of the rice lees distillate is less than 10 parts by weight, the above effect is minimal, and if the content of the rice lees distillate exceeds 30 parts by weight, the above effect is not significantly improved, and the content of galactomyces fermentation filtrate, water-soluble minerals, and beta-sitosterol is relatively excessively reduced, which may lower the functionality of the cosmetic composition, which is not preferable.
[0030]
[0031] The above SH-oligopeptide-1 is contained in an amount of 0.01 to 0.1 parts by weight and promotes the growth of epithelial cells through its role as an epithelial cell growth factor. It transmits a signal through the epidermal growth factor receptor (EGFR) on the cell membrane and induces cell division, thereby promoting the growth of epithelial cells.
[0032] In addition, the above SH-oligopeptide-1 promotes the proliferation of epithelial cells and dermal cells, promotes the cell proliferation of fibroblasts that synthesize collagen, a component of the dermis, induces the secretion of factors that promote angiogenesis and other regeneration in damaged skin areas, and plays a key role in skin regeneration, such as minimizing scars in wound areas.
[0033] At this time, the SH-oligopeptide-1 can be produced from E. coli as a single-chain human recombinant peptide, and in addition to the skin regeneration effect as described above, it exhibits a whitening effect by improving skin tone, exhibits an anti-inflammatory effect to relieve skin inflammation, and promotes collagen production to exhibit a skin wrinkle improvement effect.
[0034] If the content of the above SH-oligopeptide-1 is less than 0.01 part by weight, the above effect is minimal, and if the content of the above SH-oligopeptide-1 exceeds 0.1 part by weight, the above effect is not significantly improved, but the manufacturing cost increases excessively, which is not desirable.
[0035]
[0036] The plant extract is contained in an amount of 0.1 to 1 part by weight, and is preferably composed of at least one selected from the group consisting of aloe vera leaf extract, centella asiatica extract, licorice root extract, dandelion extract, safflower extract, ginkgo biloba extract, pomegranate extract, and mulberry bark extract, and serves to impart effects such as skin moisturizing, skin soothing, skin whitening, and wrinkle improvement to the cosmetic composition manufactured through the present invention.
[0037] At this time, the plant extract can be prepared by mixing 800 to 1200 parts by weight of an ethanol aqueous solution having a mass concentration of 65 to 75% with 100 parts by weight of the pulverized product prepared by drying ingredients such as aloe vera leaves, purslane, licorice root, dandelion, safflower, ginkgo, pomegranate, and mulberry at room temperature and then grinding the resulting product, and then performing immersion extraction at a temperature of 65 to 75°C for 10 to 15 hours.
[0038] If the content of the plant extract manufactured through the above process is less than 0.1 part by weight, the above effect is minimal, and if the content of the plant extract exceeds 1 part by weight, the above effect is not significantly improved, but the formulation stability or usability of the cosmetic composition may be deteriorated, which is not preferable.
[0039]
[0040] The above skin conditioning agent is contained in an amount of 1.5 to 2.5 parts by weight and plays a role in improving dry or damaged skin, reducing skin peeling, and restoring skin elasticity, and is preferably composed of polyglyceryl-3 methyl glucose distearate and ethylhexylglycerin, and is more preferably composed of a mixture of 100 parts by weight of polyglyceryl-3 methyl glucose distearate and 2 to 3 parts by weight of ethylhexylglycerin.
[0041]
[0042] The pH regulator is contained in an amount of 0.1 to 0.5 parts by weight and is preferably composed of citric acid, and plays a role in improving the preservative properties by controlling the acidity of the cosmetic composition manufactured through the present invention.
[0043]
[0044] The surfactant is contained in an amount of 0.5 to 1.5 parts by weight and plays a role in ensuring that the oil phase and the water phase constituting the cosmetic composition manufactured through the present invention are evenly mixed to exhibit uniform physical properties. It is preferably composed of PEG-100 stearate and polysorbate 20, and it is more preferably composed of 100 parts by weight of PEG-100 stearate mixed with 20 to 30 parts by weight of polysorbate 20.
[0045] If the content of the surfactant is less than 0.5 parts by weight, the above effect is minimal, and if the content of the surfactant exceeds 1.5 parts by weight, the above effect is not significantly improved, but skin irritation may increase excessively, which is not preferable.
[0046]
[0047] The above skin softener is contained in an amount of 4 to 6 parts by weight and serves to provide a cosmetic composition having the function of softening the skin by removing dead skin cells formed on the skin, and is preferably composed of dimethicone, a silicone-based synthetic oil.
[0048] As mentioned above, dimethicone, a silicone-based synthetic oil, has an excellent skin softening effect by adding fatty acids to silicone, and the fatty acids stabilize the silicone, giving the skin a softer feel.
[0049] If the content of the above skin softener is less than 4 parts by weight, the above effect is minimal, and if the content of the above skin softener exceeds 6 parts by weight, the above effect is not significantly improved, but the manufacturing cost excessively increases, and the skin barrier improvement effect of the cosmetic composition manufactured through the present invention may be reduced, which is not preferable.
[0050]
[0051] The above metal ion sequestering agent is contained in an amount of 0.04 to 0.06 parts by weight and is composed of disodium EDTA. It removes calcium and magnesium ions that have no affinity with cosmetic raw materials, and iron and copper ions that affect oxidation of finished products, thereby preventing deterioration of the cosmetic composition manufactured through the present invention and improving the preservation property.
[0052] If the content of the above metal ion sequestering agent is less than 0.04 parts by weight, the above effect is minimal, and if the content of the above metal ion sequestering agent exceeds 0.06 parts by weight, the above effect is not significantly improved, but the manufacturing cost increases excessively, which is not preferable.
[0053]
[0054] The above film-forming agent is contained in an amount of 0.1 to 0.3 parts by weight and is made of polyacrylate-13, and forms a film on the surface of the skin to protect the moisture of the skin.
[0055] If the content of the film-forming agent is less than 0.1 part by weight, the above effect is minimal, and if the content of the film-forming agent exceeds 0.3 part by weight, the above effect is not significantly improved, but the functionality of the cosmetic composition may be reduced, which is not preferable.
[0056]
[0057] The above thickener is contained in an amount of 0.1 to 0.5 parts by weight and is made of polyisobutene, and serves to increase the viscosity of the cosmetic composition manufactured through the present invention, thereby improving the skin application ability.
[0058] If the content of the thickener is less than 0.1 part by weight, the above effect is minimal, and if the content of the thickener exceeds 0.3 parts by weight, the above effect is not significantly improved, but the stickiness of the cosmetic composition produced may increase excessively, which may deteriorate the feeling of use, and thus it is not preferable.
[0059]
[0060] In addition, the cosmetic composition for skin soothing, moisture retention, skin tone and skin barrier improvement containing the Galactomyces may further contain 0.1 to 0.3 parts by weight of a water-soluble mineral and 0.01 to 0.1 parts by weight of a tissue regeneration substance per 100 parts by weight of the Galactomyces fermentation filtrate.
[0061] The water-soluble mineral is contained in an amount of 0.1 to 0.3 parts by weight and is manufactured by calcining coral or shells at a temperature of 850 to 950°C for 60 to 120 minutes and then pulverizing them into 800 to 1000 meshes. The water-soluble mineral manufactured through the above process not only supplies various mineral ingredients to the cosmetic composition manufactured through the present invention to improve the skin improvement effect, but also provides antibacterial properties to exhibit the effect of inhibiting deterioration.
[0062] At this time, the shells may be oyster shells, abalone shells, and pearl oyster shells.
[0063] In the process of manufacturing the above water-soluble mineral, if the calcination temperature is lower than 850°C or the calcination time is lower than 60 minutes, the calcination of coral or shells does not proceed properly, so the above effect is minimal. In addition, if the calcination temperature exceeds 950°C or the calcination time exceeds 120 minutes, the calcination process at a high temperature continues even after the coral or shells are calcined, so the above effect is no longer improved and it is not desirable in terms of energy efficiency.
[0064] In addition, the water-soluble mineral is manufactured as a powder having a particle size of 800 to 1000 mesh as described above. If the particle size of the water-soluble mineral is less than 800 mesh, the particle size is too large, so the water solubility is lowered and the feeling of use of the cosmetic composition may be deteriorated. If the particle size of the water-soluble mineral exceeds 1000 mesh, the particle size of the water-soluble mineral is too small, so it easily scatters and the water solubility may be lowered due to the clumping phenomenon between the water-soluble mineral particles, which is not preferable.
[0065] In addition, if the content of the water-soluble mineral is less than 0.1 part by weight, the above effect is minimal, and if the content of the water-soluble mineral exceeds 0.3 part by weight, the above effect is not significantly improved, but the manufacturing cost may be excessively increased, which is not preferable.
[0066] In addition, the tissue regeneration material is contained in an amount of 0.01 to 0.1 parts by weight, and is preferably composed of at least one selected from the group consisting of polynucleotides, polydeoxyribonucleotides, and hydrolyzed DNA.
[0067] The tissue regeneration material composed of the above components has effects such as promoting growth factor production, promoting angiogenesis, inducing fibrocyte differentiation, and reducing inflammation. The produced growth factors contribute to the differentiation and growth of fibroblasts, promote the production of collagen and extracellular matrix (ECM), and induce differentiation of capillaries, thereby regenerating tissue.
[0068] In addition, due to its excellent skin regeneration ability when stimulating adenosine A2a receptors in the skin, it has the effect of restoring oil-water balance, reducing sebum secretion and improving skin texture, and it also supplements elastic fibers that have decreased due to aging, increasing skin elasticity, and has the effect of improving wrinkles and increasing the overall rate of new cells, thus providing a whitening effect.
[0069] If the content of the above tissue regeneration material is less than 0.01 part by weight, the above effect is minimal, and if the content of the above tissue regeneration material exceeds 0.1 part by weight, the above effect is not significantly improved, but the preservative properties or formulation stability of the cosmetic composition may be excessively reduced, which is not preferable.
[0070]
[0071] A cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone and skin barrier improvement, comprising the above ingredients, may be formulated as one selected from the group consisting of skin lotion, skin softener, skin toner, astringent, lotion, milk lotion, moisture lotion, nourishing lotion, cream, massage cream, nourishing cream, moisture cream, hand cream, foundation, essence, nourishing essence, pack, soap, cleansing foam, cleansing lotion, cleansing cream, body cream, body lotion, body oil, body essence and body cleanser. In this case, in addition to the cosmetic composition manufactured through the present invention, any base ingredient for manufacturing the above formulation is not particularly limited and may be used as an ingredient that can generally be used in the manufacture of cosmetic formulations.
[0072]
[0073] Hereinafter, a method for manufacturing a cosmetic composition containing Galactomyces according to the present invention for skin soothing, moisture retention, skin tone and skin barrier improvement, and the physical properties of a cosmetic composition manufactured by the manufacturing method will be described with examples.
[0074]
[0075] <Manufacturing Example 1> Manufacturing of Galactomyces fermentation filtrate
[0076] 0.1 part by weight of lactic acid bacteria (Lactobacillus plantarum) was inoculated onto 100 parts by weight of Galactomyces, and fermented at a temperature of 30℃ for 24 hours. After the fermented product was crushed, centrifuged, and membrane filtered, a Galactomyces fermentation filtrate was prepared.
[0077]
[0078] <Manufacturing Example 2> Manufacturing of sterilized rice lees powder
[0079] The rice lees were sterilized by heating at a temperature of 85℃ for 30 minutes, and the sterilized rice lees were placed in a drying device and dried to have a moisture content of 12% or less. The dried rice lees were then placed in a grinder and ground to a particle size of 0.05 mm to produce sterilized rice lees powder.
[0080]
[0081] <Manufacturing Example 3> Manufacturing of rice lees distillate
[0082] 100 parts by weight of the Galactomyces fermentation filtrate manufactured through the above Manufacturing Example 1 was mixed with 30 parts by weight of the sterilized rice lees powder manufactured through the above Manufacturing Example 2 and 3 parts by weight of alcohol (butylene glycol, 1,2-hexanediol and 1,3-propanediol mixed in a weight ratio of 1:1:1) and stirred at a speed of 200 rpm for 30 minutes to prepare a mixture. After removing the solid content from the prepared mixture and distilling it, a rice lees distillate was prepared.
[0083]
[0084] <Manufacturing Example 4> Manufacturing of plant extracts
[0085] Aloe vera leaves, purslane, licorice root, dandelion, safflower, ginkgo biloba, pomegranate and mulberry bark were mixed in a weight ratio of 1:1:1:1:1:1:1:1:1:1, dried and ground, 100 parts by weight of the prepared ground product was mixed with 1000 parts by weight of an ethanol aqueous solution having a mass concentration of 70%, and a plant extract was prepared by performing a immersion extraction at a temperature of 70℃ for 12 hours and then removing the solids.
[0086]
[0087] <Manufacturing Example 5> Manufacturing of water-soluble minerals
[0088] After calcining the shell (oyster) at a temperature of 900℃ for 90 minutes, the calcined shell was crushed into 900 mesh to produce a water-soluble mineral.
[0089]
[0090] <Example 1>
[0091] 100 parts by weight of the Galactomyces fermentation filtrate manufactured through the above Manufacturing Example 1, 20 parts by weight of the rice lees distillate manufactured through the above Manufacturing Example 3, 0.05 parts by weight of SH-oligopeptide-1, 0.5 parts by weight of the plant extract manufactured through the above Manufacturing Example 4, 2 parts by weight of a skin conditioning agent (mixture of 100 parts by weight of polyglyceryl-3 methyl glucose distearate and 2.5 parts by weight of ethylhexylglycerin), 0.3 parts by weight of a pH adjusting agent (citric acid), 1 part by weight of a surfactant (mixture of 25 parts by weight of polysorbate 20 and 100 parts by weight of PEG-100 stearate), 5 parts by weight of a skin softener (dimethicone), 0.05 parts by weight of a metal ion sequestering agent (disodium EDTA), and 0.2 parts by weight of a film forming agent (polyacrylate-13). 0.3 parts by weight of a thickener (polyisobutene) was added to a mixing device equipped with a stirrer and stirred at a speed of 150 rpm for 30 minutes to prepare a cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone, and skin barrier improvement.
[0092]
[0093] <Example 2>
[0094] Proceed in the same manner as in Example 1, but 100 parts by weight of the Galactomyces fermentation filtrate prepared through Manufacturing Example 1, 10 parts by weight of rice lees distillate, 0.01 part by weight of SH-oligopeptide-1, 0.1 part by weight of the plant extract prepared through Manufacturing Example 4, 1.5 parts by weight of a skin conditioning agent, 0.1 part by weight of a pH adjusting agent, 0.5 parts by weight of a surfactant, 4 parts by weight of a skin softener, 0.04 parts by weight of a metal ion sequestering agent, 0.1 part by weight of a film-forming agent, and 0.1 part by weight of a thickener were mixed to prepare a cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone, and skin barrier improvement.
[0095]
[0096] <Example 3>
[0097] Proceed in the same manner as in Example 1, but 100 parts by weight of the Galactomyces fermentation filtrate prepared through Manufacturing Example 1, 30 parts by weight of rice lees distillate, 0.1 part by weight of SH-oligopeptide-1, 1 part by weight of the plant extract prepared through Manufacturing Example 4, 2.5 parts by weight of a skin conditioning agent, 0.5 part by weight of a pH adjusting agent, 1.5 parts by weight of a surfactant, 6 parts by weight of a skin softener, 0.06 parts by weight of a metal ion sequestering agent, 0.3 part by weight of a film forming agent, and 0.5 part by weight of a thickener were mixed to prepare a cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone, and skin barrier improvement.
[0098]
[0099] <Example 4>
[0100] The same procedure as in Example 1 was followed, but 0.2 parts by weight of the water-soluble mineral prepared in Preparation Example 5 and 0.05 parts by weight of the tissue regeneration substance (polydeoxyribonucleotide) were further mixed with 100 parts by weight of the Galactomyces fermentation filtrate to prepare a cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone, and skin barrier improvement.
[0101]
[0102] <Example 5>
[0103] Proceed in the same manner as in Example 2, but 0.2 parts by weight of the water-soluble mineral prepared in Preparation Example 5 and 0.05 parts by weight of the tissue regeneration substance (polydeoxyribonucleotide) were further mixed with 100 parts by weight of the Galactomyces fermentation filtrate to prepare a cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone, and skin barrier improvement.
[0104]
[0105] <Example 6>
[0106] The same procedure as in Example 3 was followed, but 0.2 parts by weight of the water-soluble mineral prepared in Preparation Example 5 and 0.05 parts by weight of the tissue regeneration substance (polydeoxyribonucleotide) were further mixed with 100 parts by weight of the Galactomyces fermentation filtrate to prepare a cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone, and skin barrier improvement.
[0107]
[0108] <Comparative Example 1>
[0109] 100 parts by weight of the Galactomyces fermentation filtrate manufactured through the above Manufacturing Example 1, 2 parts by weight of a skin conditioning agent (mixture of 100 parts by weight of polyglyceryl-3 methyl glucose distearate and 2.5 parts by weight of ethylhexylglycerin), 0.3 parts by weight of a pH adjusting agent (citric acid), 1 part by weight of a surfactant (mixture of 25 parts by weight of polysorbate 20 and 100 parts by weight of PEG-100 stearate), 5 parts by weight of a skin softener (dimethicone), 0.05 parts by weight of a metal ion sequestering agent (disodium EDTA), 0.2 parts by weight of a film forming agent (polyacrylate-13), and 0.3 parts by weight of a thickener (polyisobutene) were placed in a mixing device equipped with a stirrer and stirred at a speed of 150 rpm for 30 minutes to produce a skin soothing composition containing Galactomyces. A cosmetic composition for improving moisture retention capacity, skin tone, and skin barrier was prepared.
[0110]
[0111] <Comparative Example 2>
[0112] Proceed in the same manner as in Example 1, but 100 parts by weight of the Galactomyces fermentation filtrate prepared through Manufacturing Example 1, 5 parts by weight of rice lees distillate, 0.001 part by weight of SH-oligopeptide-1, and 0.01 part by weight of the plant extract prepared through Manufacturing Example 4 were mixed to prepare a cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone, and skin barrier improvement.
[0113]
[0114] <Comparative Example 3>
[0115] Proceed in the same manner as in Example 1 above, but 100 parts by weight of the Galactomyces fermentation filtrate prepared through Manufacturing Example 1, 50 parts by weight of rice lees distillate, 1 part by weight of SH-oligopeptide-1, and 5 parts by weight of the plant extract prepared through Manufacturing Example 4 were mixed to prepare a cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone, and skin barrier improvement.
[0116]
[0117] The skin whitening, skin moisturizing, skin wrinkle improvement and skin elasticity improvement effects of the cosmetic compositions for skin soothing, moisture retention, skin tone and skin barrier improvement containing Galactomyces prepared through Examples 1 to 6 and Comparative Examples 1 to 3 were measured and shown in Table 1 below.
[0118] {However, the effects of skin whitening, skin moisturizing, skin wrinkle improvement and skin elasticity improvement were measured on 50 adult male and female test subjects in their 30s to 50s. 1 mL of the manufactured cosmetic composition was applied to the neck area twice a day at 12-hour intervals for 15 days, and then the average value was expressed using a 5-point scale.
[0119] 5 points: Much improved, 4 points: Somewhat improved, 3 points: No improvement, 2 points: Worse, 1 point: Much worse}
[0120] Skin classification Skin whitening Skin moisturizing Skin wrinkles Skin elasticity Example 14.54.54.44.4 Example 24.44.44.44.4 Example 34.64.64.64.4 Example 44.64.64.54.6 Example 54.54.64.54.5 Example 64.64.64.74.6 Comparative example 13.84.14.03.9 Comparative example 24.04.24.14.0 Comparative example 34.64.64.64.5
[0121] As shown in Table 1 above, it can be seen that the cosmetic compositions manufactured through Examples 1 to 6 of the present invention have superior skin whitening, skin moisturizing, skin wrinkle improvement, and skin elasticity improvement effects compared to the cosmetic compositions manufactured through Comparative Examples 1 to 2.
[0122] On the other hand, it can be seen that even if the rice lees distillate, SH-oligopeptide-1, and the plant extract manufactured through the above manufacturing example 4 are contained in excessive amounts, as in Comparative Example 3, the skin whitening, skin moisturizing, skin wrinkle improvement, and skin elasticity improvement effects of the cosmetic composition are not significantly improved.
[0123]
[0124] In addition, the skin barrier improvement effect of the cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone and skin barrier improvement manufactured through the above Example 1 was measured and shown in Tables 2 to 3 below.
[0125] {The effect of improving the skin barrier was measured by measuring the effect on the recovery of damaged skin barrier. The measurement of the recovery of damaged skin barrier was conducted by washing the forearms of 20 adult male and female test subjects in their 30s to 50s and allowing them to rest for 30 minutes under constant temperature and humidity (20 to 24°C, 40 to 50% RH) conditions.
[0126] However, the following experiment was conducted to measure the effect on the recovery of the skin barrier damaged by external physical stimuli. The skin barrier was damaged on the forearm area using the tape stripping method, and the cosmetic composition manufactured through Example 1 was applied for 1 week to measure the transepidermal water loss (TEWL, g / m 2 h) and skin color redness average were used to evaluate the degree of recovery and soothing. At this time, the unapplied condition was used as a control group. Transepidermal water loss and skin color redness were measured using a Vapometer (Delfin, Finland) and Antera 3D (Miravex, Ireland), respectively.
[0127] Transepidermal water loss (g / m) 2 h) Before physical stimulation induction After physical stimulation induction After 1 application After 1 week of application Example 17.04 17.019.826.85 Control group 7.06 17.21 12.95 10.02
[0128]
[0129] As shown in Table 2 above, the cosmetic composition manufactured through Example 1 of the present invention showed a decrease in the transepidermal water loss measurement value after one application and one week of application compared to the transepidermal water loss measurement value after physical stimulation, indicating that the skin barrier function was effectively improved.
[0130] Skin colorRedness averageBefore physical stimulationAfter physical stimulationAfter 1 applicationAfter 1 week of applicationExample 115.8425.5216.5514.25Control 16.0126.1218.8416.69
[0131]
[0132] As shown in Table 3 above, the cosmetic composition manufactured through Example 1 of the present invention showed a decrease in the skin color redness measurement value after one application and after one week of application compared to the skin color redness measurement value after physical stimulation, indicating that the skin was soothed.
[0133]
[0134] In addition, the antioxidant activity of the cosmetic compositions for skin soothing, moisture retention, skin tone and skin barrier improvement containing Galactomyces prepared through Examples 1 to 3 and Comparative Examples 1 to 3 was measured and shown in Table 4 below.
[0135] {However, the antioxidant activity of the cosmetic composition was measured using a method of measuring the antioxidant activity by the hydrogen electron donating ability of the cosmetic composition, and a mixed sample of 0.5 mL of the extracted sample and 35 mL of DPPH (1,1-diphenyl-2-picryl hydrazyl) reagent was mixed and reacted in the dark for 30 minutes, and the absorbance was measured at 517 nm, and calculated using the following equation.
[0136] Electron donating power = 100 - (A / B × 100)
[0137] A: Absorbance of the sample addition group
[0138] B: Absorbance of the group without sample addition
[0139] Antioxidant activity (%) Example 182.0 Example 280.4 Example 383.2 Comparative Example 170.3 Comparative Example 276.5 Comparative Example 383.4
[0140]
[0141] As shown in Table 4 above, it can be seen that the cosmetic compositions manufactured through Examples 1 to 3 of the present invention have superior antioxidant activity compared to the cosmetic compositions manufactured through Comparative Examples 1 to 2.
[0142] On the other hand, it can be seen that the cosmetic compositions manufactured through Comparative Examples 1 and 2 have relatively low antioxidant activity, and it can be seen that the cosmetic composition manufactured through Comparative Example 3 does not show a significant improvement in antioxidant activity compared to Example 3, despite containing an excessive amount of rice lees distillate and plant extract.
[0143]
[0144] In addition, the skin moisture improvement effect over time of the cosmetic composition for skin soothing, moisture retention, skin tone and skin barrier improvement containing Galactomyces manufactured through Example 1 and Comparative Example 1 was measured and shown in Table 5 below.
[0145] {However, the skin moisture improvement effect was measured on 50 adult male and female test subjects in their 30s to 50s, and the method was used to measure the moisture content of the area where the cosmetic composition was applied while applying 1 mL of the manufactured cosmetic composition to the face twice a day at 12-hour intervals for 4 weeks.}
[0146] Unit of use Before use Immediately after use After use for 2 weeks After use After use for 4 weeks Example 1% 35.23±5.11 53.33±5.15 5.12±5.25 7.12±5.1 Comparative example 135.25±5.10 42.72±6.04 6.26±5.44 6.03±5.2
[0147]
[0148] As shown in Table 1 above, it can be seen that the cosmetic composition manufactured through Example 1 of the present invention has a superior skin moisture improvement effect compared to the cosmetic composition manufactured through Comparative Example 1.
[0149]
[0150] In addition, the skin itching relief effect of the cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone and skin barrier improvement manufactured through Example 1 and Comparative Example 1 was measured and shown in Table 6 below.
[0151] {However, the skin itching relief effect was measured by applying 1 mL of the manufactured cosmetic composition to the itchy skin of 20 test subjects with skin itching twice a day at 12-hour intervals for 4 weeks, and measuring the itching index of the area where the cosmetic was applied using a 4-point scale and expressing it as the average value.
[0152] 0: No itching, 1: Slight itching, 2: Itching, 3: Severe itching
[0153] Before use 2 weeks after use 4 weeks after use Example 12.211.120.09
[0154]
[0155] As shown in Table 6 above, it can be seen that the cosmetic composition manufactured through Example 1 of the present invention has an excellent skin itching relief effect due to the process of chemical component detoxification by yeast.
[0156]
[0157] Therefore, the cosmetic composition for skin soothing, moisture retention, skin tone and skin barrier improvement containing Galactomyces according to the present invention contains a large amount of natural ingredients, so it causes less skin irritation, is environmentally friendly as it is made by upcycling rice lees, and is rich in Galactomyces, vitamins, minerals and organic acid ingredients, so it exhibits effects such as skin soothing, moisture retention, skin tone, skin barrier and skin tone improvement, and prevents skin aging and skin damage and promotes skin cell regeneration to improve skin health.
Claims
1. A cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone and skin barrier improvement, characterized by comprising Galactomyces fermentation filtrate, rice lees distillate, SH-oligopeptide-1, plant extract, skin conditioning agent, pH adjusting agent, surfactant, skin softener, metal ion sequestrant, film forming agent and thickener.
2. In claim 1, The cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone and skin barrier improvement comprises 100 parts by weight of Galactomyces fermentation filtrate, 10 to 30 parts by weight of rice lees distillate, 0.01 to 0.1 parts by weight of SH-oligopeptide-1, 0.1 to 1 part by weight of plant extract, 1.5 to 2.5 parts by weight of skin conditioning agent, 0.1 to 0.5 parts by weight of pH adjusting agent, 0.5 to 1.5 parts by weight of surfactant, 4 to 6 parts by weight of skin softener, 0.04 to 0.06 parts by weight of metal ion sequestering agent, 0.1 to 0.3 parts by weight of film forming agent and 0.1 to 0.5 parts by weight of thickener. The above rice lees distillate is prepared by mixing 10 to 50 parts by weight of sterilized rice lees powder and 1 to 5 parts by weight of alcohol with 100 parts by weight of Galactomyces fermentation filtrate, removing the solid content, and then distilling it. The above sterilized rice lees powder is manufactured by sterilizing rice lees by heating them at a temperature of 80 to 90°C for 20 to 40 minutes, and then drying and grinding them. The above alcohol is composed of at least one selected from the group consisting of butylene glycol, 1,2-hexanediol and 1,3-propanediol, A cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone and skin barrier improvement, characterized in that the plant extracts are aloe vera leaf extract, centella asiatica extract, licorice root extract, dandelion extract, safflower flower extract, ginkgo biloba extract, pomegranate extract and mulberry bark extract mixed in a weight ratio of 1:1:1:1:1:1:1:1:
1.
3. In claim 1, The cosmetic composition for skin soothing, moisture retention, skin tone and skin barrier improvement containing the above Galactomyces further contains 0.1 to 0.3 parts by weight of water-soluble mineral and 0.01 to 0.1 parts by weight of tissue regeneration substance per 100 parts by weight of the above Galactomyces fermentation filtrate. The above water-soluble mineral is manufactured by calcining coral or shells at a temperature of 850 to 950°C for 60 to 120 minutes and then powdering them into 800 to 1000 meshes. A cosmetic composition containing Galactomyces for skin soothing, moisture retention, skin tone and skin barrier improvement, characterized in that the tissue regeneration material comprises at least one selected from the group consisting of polynucleotides, polydeoxyribonucleotides and hydrolyzed DNA.
Citation Information
Patent Citations
Method for Preparing of Composition for Anti-Inflammatory and Skin Regeneration Using Polydeoxyribonucleotide
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Cosmetic composition containing water-soluble minerals and method for producing the same
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