Coagulation reagent management method and system

Abstract

The present application relates to the technical field of medical devices, in particular to a coagulation reagent management method and system. The management system comprises a first reagent container, the first reagent container has at least two first reagent cavities, the at least two first reagent cavities are independently arranged to correspond to the required reagents for coagulation test items respectively, so that the first reagent container can independently complete a preset number of coagulation test items. In this way, the reagents can be managed through each coagulation test item during the reagent management and detection process, and the traditional situation of one kind of reagent being sufficient while another kind of reagent being insufficient will not occur, thereby improving the detection efficiency and saving the reagent cost. At the same time, the first reagent container is used to independently complete a preset number of coagulation test items, which also facilitates the one-time loading and replacement of the required reagents for the corresponding coagulation test items, effectively improving the efficiency of the user in loading and replacing the reagents.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of medical devices, in particular to a coagulation reagent management method and system. BACKGROUND

[0002] In the current fully automatic coagulation analyzer, coagulation reagents usually use a single glass bottle or plastic bottle as a carrier to support testing. Different types of coagulation reagents need to be packaged in different specifications of glass bottles or plastic bottles. Due to the limitations of the processing technology of commonly used glass bottles or plastic bottles, the tolerance of the bottle bottom changes greatly, plus the influence of the diameter of the large-capacity reagent bottle, which leads to the difficulty in controlling the residual amount of reagents. In the fully automatic coagulation analysis, it often causes the residual amount of reagents to increase significantly, resulting in an increase in the user's testing cost.

[0003] The existing coagulation reagent adopts the independent packaging form of mixed reagent and trigger reagent. Due to the difficulty in controlling the residual amount of reagents, the lack of mixed reagents or trigger reagents often occurs during testing, which requires users to replace reagents. Users are not easy to judge before testing whether the reagents in the current instrument can support how many tests of a certain test project, whether reagents need to be added in time, thus bringing a lot of inconvenience to reagent management. In addition, the current coagulation reagents are stored in glass bottles or plastic bottles with a general nominal volume. In the actual testing process, the instrument detects the remaining reagent height in real time to determine the remaining test quantity supported by the current reagent combined with the diameter information of the reagent bottle. Due to the large residual amount of reagents, users are difficult to complete the rated test quantity according to the nominal volume, resulting in an increase in the user's single test cost. At the same time, the real-time liquid level detection technology puts forward more complex requirements for the detection speed of the fully automatic coagulation analyzer and the reliability of the whole instrument. SUMMARY

[0004] Therefore, it is necessary to provide a coagulation reagent management method and system to solve the problem of difficulty in controlling the reagent volume in the traditional coagulation reagent packaging.

[0005] A coagulation reagent management system comprises:

[0006] A first reagent container is used to contain a predetermined amount of reagent required for a certain coagulation test project in a coagulation analyzer. The first reagent container has at least two first reagent cavities, which are independently arranged to correspond to the reagent required for the coagulation test project, so that the first reagent container can independently complete a predetermined number of coagulation test projects.

[0007] In one of the embodiments, the coagulation reagent management system further comprises a second reagent container having a second reagent container cavity, the second reagent container being used to contain additional reagents required for the customized coagulation test item, and the second reagent container being used simultaneously with the first reagent container to complete the customized coagulation test item.

[0008] In one of the embodiments, the coagulation reagent management system further comprises:

[0009] a reagent disk, the reagent disk being provided with a plurality of installation positions, each of the installation positions being used to install the first reagent container or the second reagent container; and

[0010] a controller, the controller being used to control the display device to display the installation positions of the first reagent container and the second reagent container on the reagent disk, and to control the display device to display detailed information of the reagents contained in the first reagent container and the second reagent container.

[0011] In one of the embodiments, the controller comprises a control interface, the control interface being used for a user to select the specified first reagent container and / or the second reagent container.

[0012] Alternatively, the controller can select the first reagent container and / or the second reagent container according to preset rules.

[0013] In one of the embodiments, the coagulation reagent management system further comprises a scanner connected to the controller, the scanner being used to acquire the installation position information of the first reagent container and the second reagent container, and to acquire the detailed information of the reagents contained in the first reagent container and the second reagent container, and to transmit the acquired installation position information and the detailed information of the reagents to the controller.

[0014] In one of the embodiments, the coagulation reagent management system further comprises a transfer mechanism arranged at one side of the reagent disk, the transfer mechanism being used to install the first reagent container and / or the second reagent container into the corresponding installation position, or to remove the specified first reagent container and / or the second reagent container from the installation position.

[0015] In one of the embodiments, the coagulation reagent management system further comprises a first label arranged on the first reagent container, the first label comprising at least the name information of the reagent contained in the first reagent container, and the test item information and the total test number information supported by the reagent contained in the first reagent container.

[0016] In one of the embodiments, the bottom of the first reagent container cavity comprises a tapered portion, an inner diameter area of the tapered portion gradually decreasing along the direction of gravity.

[0017] In one of the embodiments, the bottom of the first reagent container cavity further comprises a cylindrical portion and a spherical bottom surface, the tapered portion, the cylindrical portion and the spherical bottom surface being arranged in sequence and smoothly connected along the direction of gravity.

[0018] In one of the embodiments, the first reagent container further comprises a reagent bottle base and a reagent bottle cap, the reagent bottle cap is arranged on the reagent bottle base and is located at the side of the opening of the first reagent cavity, the reagent bottle cap is provided with a suction port corresponding to the opening of the first reagent cavity, and a puncture film is arranged at the suction port, and an easy-to-tear film is heat-sealed above the puncture film.

[0019] In one of the embodiments, the puncture film is made of soft rubber material, and a cross-shaped, a hoshi-shaped or a triangular opening is arranged at the center of the puncture film.

[0020] A coagulation reagent management method, comprising the following steps:

[0021] allocating reagents according to a coagulation test item set by a coagulation analyzer;

[0022] containing predetermined reagents required for the coagulation test item in a first reagent container, wherein the first reagent container has at least two first reagent cavities, and the at least two first reagent cavities are independently arranged to correspond to the predetermined reagents required for the coagulation test item one by one;

[0023] using the reagents in the first reagent container to complete the coagulation test item.

[0024] In one of the embodiments, the coagulation reagent management method further comprises the following steps:

[0025] obtaining a total test number supported by the predetermined reagents contained in the first reagent container;

[0026] recording a completed test number supported by the predetermined reagents contained in the first reagent container;

[0027] obtaining a remaining test number according to the total test number and the completed test number.

[0028] In one of the embodiments, the coagulation reagent management method further comprises the following steps:

[0029] obtaining the remaining test number, and replacing the first reagent container when the obtained remaining test number is 0.

[0030] In one of the embodiments, the coagulation reagent management method further comprises the following steps:

[0031] transporting the first reagent container with the remaining test number of 0 from the installation position to a waste hole or a buffer area; and

[0032] automatically or manually placing another first reagent container containing predetermined reagents into the installation position.

[0033] In one of the embodiments, the coagulation reagent management method further comprises the following steps:

[0034] When a custom coagulation test item needs to be performed, additional reagents required for the custom coagulation test item are accommodated in a second reagent container, the second reagent container having a second reagent accommodating cavity for accommodating the additional reagents;

[0035] The custom coagulation test item is performed using the reagents in the first reagent container and the second reagent container;

[0036] Or the custom coagulation test item is performed using the reagents in the single or multiple second reagent containers.

[0037] The beneficial effects of the present application include:

[0038] By adopting the first reagent container including at least two reagent accommodating cavities to accommodate the predetermined reagents required for a coagulation test item, the first reagent container can independently perform a preset number of the coagulation test items. In this way, the reagents can be managed by each coagulation test item in both reagent management and detection processes, and the traditional situation of one reagent being sufficient while another reagent being insufficient does not occur, thereby improving the detection efficiency and saving the reagent cost. At the same time, by independently performing a preset number of coagulation test items through the first reagent container, it is also convenient to load and replace the reagents required for the corresponding coagulation test items at one time, effectively improving the efficiency of the user to load and replace the reagents. BRIEF DESCRIPTION OF DRAWINGS

[0039] Figure 1 A structure diagram of a coagulation reagent management system provided by an embodiment of the present application;

[0040] Figure 2 A structure diagram of a coagulation reagent management system provided by an embodiment of the present application; Figure 1 A structure exploded diagram of the first reagent container in the structure shown in FIG. 1;

[0041] Figure 3 A structure exploded diagram of the first reagent container in the structure shown in FIG. 1; Figure 1 A structure cross-sectional view diagram of the installation of the first reagent container and the reagent disc in the structure shown in FIG. 1;

[0042] Figure 4 A structure exploded diagram of the first reagent container in the structure shown in FIG. 1; Figure 1 A structure exploded diagram of the first reagent container in the structure shown in FIG. 1;

[0043] Figure 5 A structure diagram of a coagulation reagent management system provided by another embodiment of the present application;

[0044] Figure 6 A flowchart of a coagulation reagent management method provided by an embodiment of the present application.

[0045] BRIEF DESCRIPTION OF DRAWINGS

[0046] 100-First reagent container;

[0047] 110 - first reagent cavity

[0048] 111 - conical portion; 112 - cylindrical portion; 113 - spherical bottom surface

[0049] 120 - reagent bottle base; 121 - anti-skid portion

[0050] 130 - reagent bottle cap; 131 - liquid suction port; 132 - puncture film; 133 - easy-to-tear film

[0051] 140 - push rod slot

[0052] 150 - mechanical hand gripping hole

[0053] 200 - second reagent container

[0054] 210 - second reagent cavity

[0055] 300 - reagent disc

[0056] 310 - mounting position

[0057] 400 - liquid suction needle DETAILED DESCRIPTION

[0058] In order to make the objectives, technical solutions, and advantages of the present application clearer, the coagulation reagent management method and system of the present application will be further described in detail below with reference to the embodiments and in conjunction with the drawings. It should be understood that the specific embodiments described herein are only used to explain the present application and should not be used to limit the present application.

[0059] It should be noted that when an element is referred to as being "on" another element, it can be directly on the other element or there can be an intervening element. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements can be present. In contrast, when an element is referred to as being "directly on" another element, there are no intervening elements present. The terms "vertical", "horizontal", "left", "right", and the like as used herein are used for explanation purposes only.

[0060] Referring to Figure 1 and Figure 2 An embodiment of the present application provides a coagulation reagent management system, which includes a first reagent container 100 for containing predetermined reagents required for a predetermined coagulation test item in a coagulation analysis instrument. The first reagent container 100 has at least two first reagent cavities 110, which are independently arranged to correspond to the predetermined reagents required for the coagulation test item, so that the first reagent container 100 can independently complete a predetermined number of coagulation test items.

[0061] Specifically, assume that the reagents required for a certain coagulation test item are a mixing reagent Rl and a trigger reagent R2. The first reagent container 100 has two first reagent cavities 110, which respectively contain the mixing reagent Rl and the trigger reagent R2. When the mixing reagent Rl and the trigger reagent R2 are filled, the added mixing reagent Rl and the trigger reagent R2 belong to the same batch and have the same shelf life. The mixing reagent Rl and the trigger reagent R2 added at the same time are added in a ratio according to the required reagent amount for the coagulation test item. For example, assume that 50 uL of the mixing reagent Rl and 100 uL of the trigger reagent R2 are required for each test, then the total volume of Rl:R2 = 1:2 is filled during filling. In this way, the first reagent container 100 can support the preset number of tests for the coagulation test item, and ensure that the remaining amount of the two reagents is substantially the same after each test, and there is no situation that one reagent is sufficient and the other reagent is insufficient. In other embodiments, if the reagents required for a certain coagulation test item are multiple, then the first reagent container 100 can also be designed to have multiple first reagent cavities 110 to respectively contain the multiple required reagents in a ratio. Alternatively, two or more first reagent containers 100 can also be combined to test the coagulation test item. Each first reagent container 100 can have two first reagent cavities 110, and each first reagent cavity 110 of each first reagent container 100 is filled with reagents in a ratio according to the amount of each reagent.

[0062] In addition, in the coagulation test item, some items only require the trigger reagent R2 and do not require the mixing reagent Rl. For these test items, such as the PT item, at least two first reagent cavities 110 in the first reagent container 100 supporting the item can only have the required trigger reagent R2 in one of the first reagent cavities 110, and the other first reagent cavities 110 are not filled with reagents and are empty. Alternatively, all the first reagent cavities 110 can be filled with the required trigger reagent R2. For example, as shown in FIG. 1C, the first reagent container 100 has two first reagent cavities 110, one of which contains the first reagent required for any coagulation test item, and the other of which contains the second reagent corresponding to the first reagent, or contains the first reagent, or is empty. Thus, two or one reagents can be contained in the first reagent container 100 according to the supported coagulation test item, so that the corresponding coagulation test item can be smoothly performed without the user adding reagents himself / herself. Figure 2

[0063] ​When each first reagent container 100 is filled, the total number of tests supported by each first reagent container 100 for the coagulation test item, and the reagent type, name, batch number, expiration date, and the like of the filled reagent can be directly given. In one embodiment, the coagulation reagent management system further includes a first label (not shown) provided on the first reagent container 100. The first label contains at least the name of the reagent contained in the first reagent container 100, and the test item information and the total number of tests supported by the reagent contained in the first reagent container 100. The first label can be a bar code, a two-dimensional code, or an RFID reader / writer (Radio Frequency Identification Reader / Writer). When each first reagent container 100 is shipped, the information is written into the first label and fixed on the corresponding first reagent container 100. Thus, the detailed information of the reagent contained in each first reagent container 100 can be obtained by acquiring the information on the first label. In specific use, by reading the information on the first label, the coagulation test item and the total number of tests supported by the first reagent container 100 can be obtained. After each test is completed, the number of tests supported by the first reagent container 100 is recorded, and then the remaining number of tests can be accurately obtained according to the total number of tests and the number of tests supported. In this way, the remaining number of tests of the reagent does not need to be counted by using the liquid level detection technology as in the prior art, and the problem of inaccurate results caused by mechanical errors is overcome, and the instrument test speed and the overall reliability are improved.

[0064] It is worth noting that the information contained in the first label includes not only the reagent name, the supported test item, and the total number of tests supported, but also the production date of the reagent, the expiration date (such as the sealed expiration date or the expiration date after opening), the ID code of the reagent container, and / or the calibration information, and the like.

[0065] The coagulation reagent management system of the present embodiment uses a first reagent container 100 including at least two reagent cavities to contain the predetermined reagent required for a coagulation test item, and the first reagent container 100 can independently complete the predetermined number of tests of the coagulation test item. In this way, the reagent can be managed by each coagulation test item in the reagent management and detection process, and the situation that one reagent is sufficient while another reagent is insufficient does not occur, thereby improving the detection efficiency and saving the reagent cost. At the same time, the first reagent container 100 is used to independently complete the predetermined number of tests of the coagulation test item, which facilitates the one-time loading and replacement of the reagent required for the corresponding coagulation test item, and effectively improves the efficiency of the user in loading and replacing the reagent.

[0066] Referring to Figure 4As shown, in one implementable manner, the bottom of the first reagent cavity 110 includes a conical portion 111, the inner diameter area of ​​which gradually decreases along the direction of gravity. By designing the first reagent cavity 110 with a conical portion 111 at the bottom, reagent at the bottom can be easily aspirated, reducing the bottom dead volume and reagent residue, thereby effectively saving reagent and reducing reagent costs. For example, as... Figure 4 As shown, the bottom of the first reagent cavity 110 includes a conical portion 111, a cylindrical portion 112, and a spherical bottom surface 113 arranged sequentially along the direction of gravity. The conical portion 111, the cylindrical portion 112, and the spherical bottom surface 113 are smoothly connected. The conical portion 111 facilitates the accumulation of reagent at the spherical bottom surface 113, while the cylindrical portion 112 increases the amount of reagent that can be accumulated at the bottom of the first reagent cavity 110, making it easier for the aspiration needle 400 to draw up the reagent.

[0067] See Figure 2 In one embodiment, the first reagent container 100 further includes a reagent bottle base 120 and a reagent bottle cap 130. The reagent bottle cap 130 is disposed on the reagent bottle base 120 and located on the side where the opening of the first reagent cavity 110 is located. The reagent bottle cap 130 has a suction port 131 corresponding to the opening of the first reagent cavity 110. A puncture membrane 132 is disposed at the suction port 131, and an easy-tear film 133 is heat-sealed on top of the puncture membrane 132.

[0068] It is understood that the first reagent cavity 110 can be directly formed on the reagent bottle base 120. See also Figure 2 In one embodiment, the reagent bottle base 120 has at least two chambers, and the inner wall of each chamber forms a first reagent cavity 110 for containing reagents. In actual production, at least two chambers can be molded on a single reagent bottle base 120 to form an integral first reagent container 100 with at least two first reagent cavities 110. The reagent bottle base 120 is provided with a reagent bottle cap 130, which has a suction port 131. The suction port 131 is provided with a puncture membrane 132 and an easy-tear membrane 133. The puncture membrane 132 is a structure that integrates sealing and anti-evaporation functions with a puncture function. Figure 4 As shown, the puncture membrane 132 can be made of soft rubber, with a cross-shaped, star-shaped, or triangular opening in its center to allow the aspiration needle 400 to be inserted smoothly. Alternatively, the puncture membrane 132 can be a completely sealed membrane made of soft rubber, without any openings. When the aspiration needle 400 needs to aspirate liquid from the first reagent cavity 110, it can simply puncture the puncture membrane 132. Figure 2As shown, the puncture film 132 and the reagent bottle cap 130 can be independent structures. In other embodiments, the reagent bottle cap 130 and the puncture film 132 can also be designed as an integrated soft gel puncture cover structure. The easy-to-tear film 133 can be a single film corresponding to each liquid suction port 131. The easy-to-tear film 133 can also be a long strip of easy-to-tear film, which can simultaneously seal multiple liquid suction ports 131. By providing the easy-to-tear film 133, the reagent can be reliably sealed after the first reagent container 100 is filled with reagent, and the easy-to-tear film 133 can be easily removed to activate the reagent during use. By providing the puncture film 132, the amount of reagent volatilization after activation can be greatly reduced, the in-machine stability of the reagent can be improved, and the detection performance can be improved.

[0069] In other embodiments, the first reagent container cavity 110 can also be formed by a separate bottle, which is integrated into a reagent bottle base 120 to form a first reagent container 100 with at least two first reagent container cavities 110. As an example, the reagent bottle base 120 includes at least two fixing grooves, each of which is fixed with a reagent bottle, and the inner wall of the reagent bottle forms a first reagent container cavity 110 for containing reagent. A puncture film 132 can be provided at the bottle opening of each reagent bottle, and an easy-to-tear film 133 can be heat-sealed above the puncture film 132. Through the easy-to-tear film 133 and the puncture film 132, reliable sealing of the unactivated reagent can be achieved, while reducing the amount of reagent volatilization after activation, improving the in-machine stability of the reagent, and improving the detection performance.

[0070] Referring to Figure 2 As shown, in one embodiment, the reagent bottle base 120 is provided with an anti-slip portion 121. The anti-slip portion 121 is an anti-slip cone or anti-slip cone hole, or anti-slip stripes provided on the side wall of the reagent bottle base 120. By providing the anti-slip portion 121, the user can easily grasp the first reagent container 100.

[0071] Referring to Figure 1 As an implementable way, the coagulation reagent management system further includes a second reagent container 200, and the second reagent container 200 has a second reagent container cavity 210. The second reagent container 200 is used to contain additional reagents required for a self-defined coagulation test item, and the second reagent container 200 is used together with the first reagent container 100 to complete the self-defined coagulation test item. By adding the second reagent container 200, the reagents in the second reagent container 200 can be combined with the reagents in the first reagent container 100 to complete the self-defined coagulation test item, thereby meeting the needs of customers using a variety of third-party reagents, and realizing open reagent management and use.

[0072] Specifically, the first reagent container 100 contains the predetermined reagents required by the test items provided by the instrument, and the second reagent container 200 contains the third-party reagents, i.e. the additional reagents required by the user-defined coagulation test items. There can be multiple second reagent containers 200, each of which is used to place a kind of third-party reagent, so that the multiple second reagent containers 200 and the first reagent container 100 can jointly complete the user-defined coagulation test items. The second reagent container 200 can be provided with a second label, which can include information such as reagent type, name, production date, expiration date (such as sealed expiration date or opened expiration date), ID code of the reagent container, and the like.

[0073] In other embodiments, the reagents in the second reagent container 200 can also be used individually according to actual needs to complete corresponding coagulation test items. For example, the PT item only needs to use the trigger reagent R2. At this time, the second reagent container 200 can be used to contain a certain amount of R2 to support the completion of a preset number of PT items.

[0074] Referring to Figure 1 , as an implementable way, the coagulation reagent management system further includes a reagent tray 300 and a controller (not shown). The reagent tray 300 is provided with a plurality of mounting positions 310, each of which is used to mount the first reagent container 100 or the second reagent container 200. The controller is used to control the display device (not shown) to display the mounting positions of the first reagent container 100 and the second reagent container 200 on the reagent tray 300, and to control the display device to display the detailed information of the reagents contained in the first reagent container 100 and the second reagent container 200. It can be understood that, as shown in Figure 1 , the reagent tray 300 can be a circular reagent tray, and the plurality of mounting positions 310 are distributed along the circumferential direction of the reagent tray 300. As shown in Figure 5 , the reagent tray 300 can also be a rectangular reagent tray, and the plurality of mounting positions 310 can be distributed along the longitudinal direction of the reagent tray 300. The reagent bottle base 120 of the first reagent container 100 can be provided with a fixing structure, such as an elastic buckle, for fixing the first reagent container 100 to the reagent tray 300. Correspondingly, the reagent tray 300 is provided with a structure cooperating with the fixing structure on the reagent bottle base 120, such as two pin holes cooperating with the elastic buckle.

[0075] Each installation site 310 of the reagent disc 300 can be provided with a position label containing information such as the ID of the installation site 310. The display device can have display areas corresponding to the shape of the reagent disc 300 and each installation site 310 one by one. It can be understood that one installation site 310 can only correspond to the installation of one first reagent container 100 or one second reagent container 200. The reagent disc 300 can only be installed with first reagent containers 100 or second reagent containers 200. The reagent disc 300 can also be installed with both first reagent containers 100 and second reagent containers 200. Assuming that the reagent disc 300 is installed with multiple first reagent containers 100, when the first reagent container 100 is installed at a certain installation site 310, the controller can obtain the information of the first label on the first reagent container 100 and the information of the position label of the installation site 310, and bind the two together to be displayed on the corresponding position of the display area of the display device.

[0076] The controller can obtain the corresponding information in various ways. In one embodiment, the coagulation reagent management system further comprises a scanner (not shown) connected with the controller. The scanner is used to obtain the installation position information of the first reagent container 100 and the second reagent container 200, and obtain the detailed information of the reagents contained in the first reagent container 100 and the second reagent container 200, and transmit the obtained installation position information and the detailed information of the reagents to the controller. By scanning the position label of the installation site 310 to be installed, and the first label or the second label corresponding to the installation of the installation site 310, and sending the scanned information to the controller, the controller can obtain the corresponding information.

[0077] In one embodiment, the controller comprises a control interface (not shown) for the user to select a specified first reagent container 100 and / or second reagent container 200. It can be understood that the control interface can be a touch interface or a key interface, and the control interface is provided on the display device corresponding to the display area of the display device. Through the control interface, the user can select the specified first reagent container 100 and / or second reagent container 200 on the reagent disc 300 according to the needs to perform the coagulation test item in a touch or press manner.

[0078] Alternatively, the controller can select the first reagent container 100 and / or the second reagent container 200 according to a preset rule. The preset rule refers to a default selection rule written into the controller program, such as a rule of preferentially selecting a reagent container with an earlier production date for use, or a rule of preferentially using a reagent container that has been opened. Specifically, when a plurality of first reagent containers 100 are installed on the reagent disk 300, the controller has obtained the installation positions of the respective first reagent containers 100 and detailed information of the reagents contained therein. That is, the controller is aware of the positions of the respective first reagent containers 100, as well as information such as the coagulation test items supported by the first reagent containers 100 and the production dates of the reagents contained therein. Therefore, the controller can select a first reagent container 100 for use according to the preset rule, such as preferentially selecting a reagent container with an earlier production date for use, or preferentially selecting a first reagent container 100 that has been opened for use when the same coagulation test item is to be tested next time.

[0079] In one embodiment, the coagulation reagent management system further comprises a transfer mechanism (not shown) arranged on one side of the reagent disk 300. The transfer mechanism is used to install the first reagent container 100 and / or the second reagent container 200 into the corresponding installation position 310, or to remove the designated first reagent container 100 and / or the second reagent container 200 from the installation position 310. The transfer mechanism can be an electrically controlled push rod mechanism, and the reagent bottle base 120 of the first reagent container 100 can be provided with a push rod groove 140 for clamping with one end of the electrically controlled push rod. By means of the electrically controlled push rod, the reagent bottle base 120 can be installed onto the reagent disk 300 or detached from the reagent disk 300, thereby achieving automatic loading and unloading of the first reagent container 100. In other embodiments, the transfer mechanism can also be a mechanical hand, and the reagent bottle base can be provided with a mechanical hand gripping hole 150.

[0080] Referring to Figure 6 , one embodiment of the present application further provides a coagulation reagent management method, comprising the following steps:

[0081] allocating reagents according to a coagulation test item set by a coagulation analyzer;

[0082] containing predetermined reagents required for the coagulation test item in a first reagent container 100. As shown in Figure 2 , the first reagent container 100 has at least two first reagent cavities 110 arranged independently of each other to respectively and correspondingly contain predetermined reagents required for the coagulation test item;

[0083] completing the coagulation test item using the first reagent container 100.

[0084] The coagulation reagent management method can manage the reagents through each coagulation test item in the reagent management and detection processes, and the traditional situation of one reagent being sufficient while another reagent being insufficient does not occur, thereby improving the detection efficiency and saving the reagent cost. Meanwhile, the first reagent container 100 is used to independently complete the preset number of coagulation test items, and it is convenient to load and replace the reagents required by the corresponding coagulation test items at one time, thereby effectively improving the efficiency of the user in loading and replacing the reagents.

[0085] In one embodiment, the coagulation reagent management method further comprises the following steps: when a custom coagulation test item needs to be performed, accommodating the additional reagents required by the custom coagulation test item in the second reagent container 200, the second reagent container 200 having a second reagent cavity 210 for accommodating the additional reagents; using the reagents in the first reagent container 100 and the second reagent container 200 to complete the custom coagulation test item; or using the reagents in the single or multiple second reagent containers 200 to complete the custom coagulation test item.

[0086] By adding the second reagent container 200, the reagents in the second reagent container 200 can be combined with the reagents in the first reagent container 100 to complete the custom coagulation test item of the user, thereby being able to meet the needs of customers using a variety of third-party reagents, and realizing open reagent management and use. In addition, the container in the second reagent container 200 can also be used alone according to the actual needs to complete the custom coagulation test item of the user, thereby improving the flexibility of reagent management.

[0087] In one embodiment, the coagulation reagent management method further comprises the following steps:

[0088] Obtaining the total test number supported by the predetermined reagents accommodated in the first reagent container 100;

[0089] Recording the completed test number supported by the predetermined reagents accommodated in the first reagent container 100;

[0090] Obtaining the remaining test number according to the total test number and the completed test number.

[0091] Specifically, the functions of obtaining, recording and calculating can be realized by the controller. When each first reagent container 100 is filled, the total test number of the coagulation test item supported by the respective first reagent container 100 is written into the first label. The controller can obtain the total test number by scanning the first label through the scanner. The controller can also automatically record the completed test number through the memory. Finally, the controller can calculate the remaining test number supported by the reagent in the first reagent container 100 according to the total test number and the completed test number. Therefore, it is no longer necessary to use technologies such as liquid level detection to count the remaining test number of the reagent as in the prior art, and the problem of inaccurate results caused by mechanical errors is overcome, and the test speed of the instrument and the overall reliability of the instrument are improved.

[0092] Further, the coagulation reagent management method further comprises the following steps:

[0093] Obtaining the remaining test number, and replacing the first reagent container 100 when the obtained remaining test number is 0.

[0094] It can be understood that the way of replacing the first reagent container 100 can be mechanical automatic replacement or manual replacement. When the mechanical automatic replacement is used, the controller sends a replacement instruction to the transfer mechanism, and the transfer mechanism removes the specified first reagent container 100 (i.e., the first reagent container 100 with a remaining test number of 0) from the corresponding mounting position 310. When the manual replacement is used, the controller controls the display device to display the position of the first reagent container 100 to be replaced, and then the user can manually remove the specified first reagent container 100 from the corresponding mounting position 310. Exemplarily, the replacement process includes transporting the first reagent container 100 with a remaining test number of 0 from the mounting position 310 to a waste hole (for disposal) or a buffer area (for the user to take away), and automatically or manually placing another first reagent container 100 containing the predetermined reagent into the mounting position 310.

[0095] The technical features of the above-described embodiments can be combined in any manner. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described, but as long as the combinations of the technical features do not contradict each other, they should be considered within the scope of the present disclosure.

[0096] The above-described embodiments only express several embodiments of the present application, and the description is relatively specific and detailed, but it should not be understood as a limitation on the scope of the patent. It should be noted that for ordinary skilled persons in the art, without departing from the concept of the present application, a number of modifications and improvements can be made, which are within the scope of the present application. Therefore, the protection scope of the present patent should be subject to the appended claims.

Claims

1. A coagulation reagent management system, characterized by, The system comprises: a plurality of first reagent containers for containing predetermined reagents required for a preset coagulation test item in a coagulation analyzer, each of the first reagent containers having at least two first reagent cavities arranged independently to correspondingly contain the predetermined reagents required for the coagulation test item, the predetermined reagents being mixed reagents and trigger reagents, and the two first reagent cavities containing the mixed reagents and the trigger reagents respectively, so that each of the first reagent containers can independently complete the preset number of coagulation test items; the first reagent container comprises a reagent bottle base, the reagent bottle base comprises at least two fixing grooves, each of the fixing grooves is fixed with a reagent bottle, the inner wall of the reagent bottle forms the first reagent cavity containing the reagent, the bottom of each of the first reagent cavities is a smooth spherical bottom surface, the predetermined reagents gather towards the spherical bottom surface, a puncture film is arranged at the bottle mouth of each of the reagent bottles, the puncture film is made of soft rubber material, and a cross-shaped, rice-shaped or triangular opening is formed at the center of the puncture film to enable a suction needle to pass through the puncture film and suck the predetermined reagents gathered on the spherical bottom surface; a reagent disc is provided with a plurality of mounting positions, the reagent bottle base of the first reagent container is provided with a fixing structure for fixing the first reagent container and the reagent disc, and the reagent disc is provided with a structure matched with the fixing structure on the reagent bottle base; a controller controls the suction needle to suck the predetermined reagents contained in the first reagent container to independently complete the preset number of coagulation test items.

2. The coagulation reagent management system according to claim 1, characterized in that, The fixing structure on the reagent bottle base of the first reagent container is an elastic buckle, and the structure matched with the fixing structure on the reagent bottle base on the reagent disc is a pin.

3. The coagulation reagent management system of claim 1, wherein, A transfer mechanism is arranged on one side of the reagent disc, and the transfer mechanism is used to mount the first reagent container to the corresponding mounting position or remove the specified first reagent container from the mounting position and transport it to a waste hole to discard the first reagent container; the controller controls the transfer mechanism to mount the first reagent container to be loaded to the corresponding mounting position of the reagent disc, so that the fixing structure arranged on the reagent bottle base of the first reagent container is matched with the matched structure at the corresponding mounting position of the reagent disc to mount the first reagent container to the corresponding mounting position, and controls the transfer mechanism to remove the first reagent container to be discarded from the mounting position and transport it to the waste hole to discard the first reagent container.

4. The coagulation reagent management system of claim 1, wherein, Each of the first reagent cavities of each of the first reagent containers is filled with reagents according to the proportion of the amount of each reagent.

5. The coagulation reagent management system of claim 3, wherein, A second reagent container having a second reagent cavity is further included, and the second reagent container is used to contain additional reagents required for a self-defined coagulation test item, and the second reagent container is used simultaneously with the first reagent container to complete the self-defined coagulation test item.

6. The coagulation reagent management system according to claim 5, wherein Each of the mounting positions is used for mounting the first reagent container or the second reagent container respectively; and The controller is used for controlling the display device to display the mounting positions of the first reagent container and the second reagent container on the reagent disk, and controlling the display device to display detailed information of reagents contained in the first reagent container and the second reagent container.

7. The coagulation reagent management system according to claim 6, characterized in that, The controller comprises a control interface used for a user to select a specified first reagent container and / or a specified second reagent container; Alternatively, the controller is capable of selecting the first reagent container and / or the second reagent container according to preset rules.

8. The coagulation reagent management system of claim 6, wherein, Further comprising a scanner connected with the controller, the scanner is used for acquiring mounting position information of the first reagent container and the second reagent container, and acquiring detailed information of reagents contained in the first reagent container and the second reagent container, and transmitting the acquired mounting position information and the detailed information of the reagents to the controller.

9. The coagulation reagent management system of claim 6, wherein, The transfer mechanism is used for mounting the second reagent container to the corresponding mounting position, or removing the specified second reagent container from the mounting position.

10. The coagulation reagent management system of claim 1, wherein, Further comprising a first label arranged on the first reagent container, the first label at least contains name information of a reagent contained in the first reagent container, and test item information and total test number information supported by the reagent contained in the first reagent container.

11. The coagulation reagent management system of claim 1, wherein, The bottom of the first reagent container cavity comprises a tapered portion, an inner diameter area of the tapered portion gradually decreases along the gravity direction.

12. The coagulation reagent management system of claim 11, wherein, The bottom of the first reagent container cavity further comprises a cylindrical portion, the tapered portion, the cylindrical portion and the spherical bottom surface are sequentially arranged and smoothly connected along the gravity direction.

13. The coagulation reagent management system of claim 1, wherein, The first reagent container further comprises a reagent bottle cap arranged on the reagent bottle base and located on a side of the opening of the first reagent container cavity, the reagent bottle cap is provided with a liquid suction port corresponding to the opening of the first reagent container cavity, the puncture film is arranged at the liquid suction port, and a layer of easy-to-tear film is heat-sealed above the puncture film.

14. A coagulation reagent management method characterized by, The coagulation reagent management system of any one of claims 1-13 comprises the following steps: allocating reagents according to a certain coagulation test item set by a coagulation analyzer; containing the predetermined reagent required for the coagulation test item in a first reagent container, wherein the first reagent container has at least two first reagent cavities, and the at least two first reagent cavities are independently arranged to correspond to the predetermined reagent required for the coagulation test item one by one; using the reagents in the first reagent container to complete the coagulation test item.

15. The coagulation reagent management method according to claim 14, characterized by, Further comprising the following steps: obtaining the total test number supported by the predetermined reagent contained in the first reagent container; recording the completed test number supported by the predetermined reagent contained in the first reagent container; obtaining the remaining test number according to the total test number and the completed test number.

16. The coagulation reagent management method according to claim 15, characterized by, Further comprising the following steps: obtaining the remaining test number, and replacing the first reagent container when the obtained remaining test number is 0.

17. The coagulation reagent management method according to claim 16, characterized by, Further comprising the following steps: transporting the first reagent container with the remaining test number of 0 from the mounting position to a waste hole or a buffer area; and automatically or manually placing another first reagent container containing a predetermined reagent into the mounting position.

18. The coagulation reagent management method according to claim 14, characterized by, Further comprising the steps of: when a custom coagulation test item is required, accommodating additional reagents required for the custom coagulation test item in a second reagent container, the second reagent container having a second reagent accommodating cavity for accommodating the additional reagents; using the reagents in the first reagent container and the second reagent container to complete the custom coagulation test item; or using the reagents in the single or multiple second reagent containers to complete the custom coagulation test item.

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