A high-pressure cell culture chamber with quick opening and closing functions

By designing a fast opening and closing structure in the high-pressure cell culture chamber, using the combination of three-flap clamps and rotating rods, the problem of cumbersome operation of the hatch door is solved, and the effect of quickly closing and opening the hatch door is achieved.

CN117801947BActive Publication Date: 2025-03-04CHINESE PEOPLES LIBERATION ARMY NAVAL SPECIALTY MEDICAL CENT
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Patent Information

Application Number
CN202311271372.3
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2023-09-28
Publication Date
2025-03-04
Estimated Expiration
2043-09-28

AI Technical Summary

Technical Problem

The operation of closing and opening the doors of the existing high-pressure cell culture chamber is troublesome, and it requires loosening and locking bolts one by one, resulting in cumbersome operation.

Method used

A fast opening and closing structure is designed, using a combination of three-flap clamps and rotary rods. The three-flap clamps are clamped by rotating the rotary rods, and the limiting rods are limited by the slight movement of the moving blocks, thereby quickly closing and opening the hatch door.

Benefits of technology

It realizes the quick opening and closing of the hatch door, and the operation is relatively simple, which improves the efficiency of the hatch door.

✦ Generated by Eureka AI based on patent content.

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    Figure CN117801947B_ABST
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Abstract

The present invention discloses a high-pressure cell culture chamber with a quick opening and closing function. The chamber door is pushed toward the hatch direction, the rotating shaft rotates, the chamber door is closed, the opening of the chamber door is docked with the hatch, and the opening of the chamber door is accommodated in the three-petal clamp. The rotating rod is rotated, and under the drive of the positive and negative screw teeth, the first petal part and the second petal part of the three-petal clamp move relatively close to each other to realize the clamping of the chamber door by the three-petal clamp, and the moving block is slightly moved forward, and the left and right limit rods pass through the long strip holes of the limit block, and the left limit rod is just limited to the left end of the long strip hole, and the right limit rod is just limited to the right end of the long strip hole, so as to realize the quick closing of the chamber door; the moving block is slightly moved backward, the left limit rod and the right limit rod do not pass through the long strip holes of the limit block, and the rotating rod is rotated in the opposite direction. Under the drive of the positive and negative screw teeth, the first petal part and the second petal part of the three-petal clamp move away from each other in the opposite direction, and the chamber door is pushed in the direction away from the hatch, and the rotating shaft rotates to open the chamber door, so as to realize the quick opening of the chamber door.
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Description

Technical Field

[0001] The invention relates to the technical field of cell culture devices, in particular to a high-pressure cell culture chamber with quick opening and closing functions. Background Art

[0002] This unit and the university have previously jointly designed a high-pressure cell culture chamber and applied for a patent, with the application number 2018115822134. The fixing structure of the door and the cabin of the high-pressure cell culture chamber is: bolt bayonet holes are respectively set on the extended fixed corners of the four corners of the door, and bolt seats are respectively set at the four corner positions of the door frame of the cabin body corresponding to the door. The bolt seat is centrally connected to the bolt, and the movable end of the bolt is inserted into the bolt bayonet and locked by the nut, so that the door is sealed and fastened outside the door frame of the cabin body. When the door needs to be closed, this fixing structure requires the movable ends of the four bolts to be respectively inserted into the corresponding bolt bayonet holes, and then the nuts on the four bolts are locked to close the door. When the door needs to be opened, this fixing structure requires the bolts at the four corner positions to be loosened one by one, and then the movable ends of the four bolts are respectively pulled out from their corresponding bolt bayonet holes to open the door. The operation of closing and opening the door is relatively troublesome. The designer of the present invention has designed a quick opening and closing structure so that the door can be opened and closed quickly. Summary of the invention

[0003] The present invention aims at the problems and shortcomings of the prior art and provides a novel high-pressure cell culture chamber with quick opening and closing functions.

[0004] The present invention solves the above technical problems through the following technical solutions:

[0005] The present invention provides a high-pressure cell culture chamber with a quick opening and closing function, which is characterized in that the high-pressure cell culture chamber is a horizontal cylindrical single-chamber one-door structure, including a chamber body, one end of the chamber body adopts a standard elliptical head, the other end of the chamber body is sleeved and fixed with a fixed ring frame, and the other end is provided with a hatch, a three-petal clamp is fixed on the fixed ring frame along the edge of the hatch, a left limiting rod is fixed to the top outer side of the first petal of the three-petal clamp, and a right limiting rod is fixed to the top outer side of the second petal relative to the third petal, a left inverted U-shaped moving frame is fixed to the top outer surface of the first petal of the three-petal clamp, and a right inverted U-shaped moving frame is fixed to the top outer surface of the second petal relative to the third petal, a rotating rod is penetrated through the top of the left inverted U-shaped moving frame and the top of the right inverted U-shaped moving frame, a forward screw thread is provided on the left part of the rotating rod, and a reverse screw thread is provided on the right part of the rotating rod, the top of the left inverted U-shaped moving frame is located on the forward screw thread, and the top of the right inverted U-shaped moving frame is located on the reverse screw thread.

[0006] Two fixed bases are fixed at intervals at the middle position of one side of the fixed ring frame and close to the position of the three-petal clamp, a vertical fixed rod is fixed between the two fixed bases, the upper and lower parts of the vertical fixed rod are respectively provided with rotating shafts, the two rotating shafts are fixedly connected to the elliptical cabin door through a connecting block, a fixed column is fixed on the top of the cabin door, a fixed limiting ring is provided on the fixed column, a moving block is provided on the fixed column, the moving block is limited between the limiting ring and the top of the cabin door, a waist-shaped hole is provided on the moving block to enable the moving block to move slightly forward and backward on the fixed column, a limiting block is fixed on the front end of the moving block, and a long strip hole is provided on the limiting block.

[0007] The hatch door is pushed toward the hatch direction, the rotating shaft rotates, the hatch door is closed, the hatch opening is docked with the hatch, the hatch opening is accommodated in the three-petal clamp, the rotating rod is rotated, and under the drive of the forward screw thread and the reverse screw thread, the first petal and the second petal of the three-petal clamp move closer to each other to achieve the three-petal clamp clamping the hatch door, the moving block is slightly moved forward, the left limit rod and the right limit rod pass through the elongated hole of the limit block, and the left limit rod is just limited to the left end of the elongated hole of the limit block, and the right limit rod is just limited to the right end of the elongated hole of the limit block, thereby achieving rapid closing of the hatch door.

[0008] The moving block is slightly moved backward, and the left limit rod and the right limit rod do not pass through the long hole of the limit block. The rotating rod is rotated in the opposite direction. Driven by the forward screw thread and the reverse screw thread, the first petal and the second petal of the three-petal clamp move away from each other, pushing the hatch away from the hatch, and the rotating shaft rotates to open the hatch, thereby realizing the rapid opening of the hatch.

[0009] When the hatch needs to be closed, the present invention only needs to rotate the rotating rod so that the three-petal clamp clamps the hatch, and then slightly move the moving block forward so that the left limit rod and the right limit rod on the three-petal clamp are limited in the long strip hole of the limit block, so that the hatch can be quickly closed. When the hatch needs to be opened, the moving block only needs to slightly move backward so that the left limit rod and the right limit rod are not in the long strip hole of the limit block, and the rotating rod is rotated in the opposite direction so that the three-petal clamp releases the hatch. The operation is relatively simple, and the hatch can be quickly opened and closed. BRIEF DESCRIPTION OF THE DRAWINGS

[0010] Figure 1-3 This is a schematic diagram of the three-dimensional structure of a high-pressure cell culture chamber with quick opening and closing functions according to a preferred embodiment of the present invention. DETAILED DESCRIPTION

[0011] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0012] like Figure 1-3 As shown, this embodiment provides a high-pressure cell culture chamber with a quick opening and closing function. The high-pressure cell culture chamber is a horizontal cylindrical single-chamber one-door structure. One end of the high-pressure cell culture chamber adopts a standard elliptical head. The material steel grade of the high-pressure cell culture chamber is 16MnR. The design pressure of the high-pressure cell culture chamber is 2.5MPa and the maximum working pressure is 2MPa.

[0013] The high-pressure cell culture chamber comprises a chamber body 1, one end of which adopts a standard elliptical head, the other end of which is sleeved and fixed with a fixed ring frame 2, and the other end is provided with a hatch 3, a three-petal clamp 4 is fixed on the fixed ring frame 2 along the edge of the hatch 3, a left limiting rod 5 is fixed to the top outer side of the first petal of the three-petal clamp 4, and a right limiting rod 6 is fixed to the top outer side of the second petal, a left inverted U-shaped moving frame 7 is fixed to the top outer surface of the first petal of the three-petal clamp 4, and a right inverted U-shaped moving frame 8 is fixed to the top outer surface of the second petal, and the top and right inverted U-shaped moving frames 7 and 8 are fixed to the top and right of the left inverted U-shaped moving frame 7. A rotating rod 9 is passed through the top of the U-shaped movable frame 8, and a forward screw thread is provided on the left portion of the rotating rod 9 and a reverse screw thread is provided on the right portion (although not shown in the figure, the forward screw thread and the reverse screw thread are existing components, and how the forward screw thread and the reverse screw thread are fixed on the rod is an existing technology). The top of the left inverted U-shaped movable frame 7 is located on the forward screw thread, and the top of the right inverted U-shaped movable frame 8 is located on the reverse screw thread. The rotating rod 9 is covered with a blind plate cover 10, and the left side of the blind plate cover 10 is sleeved on the left side of the rotating rod 9, and the right side of the blind plate cover 10 is sleeved on the right side of the rotating rod 9, and the forward screw thread and the reverse screw thread are placed in the blind plate cover 10.

[0014] Two fixed bases 21 are fixed at intervals at the middle position on the right side of the fixed ring frame 2 and close to the position of the three-petal clamp 4, a vertical fixed rod 11 is fixed between the two fixed bases 21, the upper and lower parts of the vertical fixed rod 11 are respectively sleeved with rotating shafts 12, the two rotating shafts 12 are fixedly connected to the elliptical hatch 14 through a connecting block 13, a fixed column 15 is fixed to the top of the hatch 14, a fixed limit ring 16 is sleeved on the fixed column 15, the fixed column 15 and the limit ring 16 are integrally formed, a moving block 17 is sleeved on the fixed column 15, the moving block 17 is limited between the limit ring 16 and the top of the hatch 14, a waist-shaped hole 18 is opened on the moving block 17 so that the moving block 17 can move slightly forward and backward on the fixed column 15, a limiting block 19 is fixed to the front end of the moving block 17, and a long hole 20 is opened on the limiting block 19.

[0015] A sliding cell culture tray 22 is arranged in the cabin 1 along the length direction. The cell culture tray 22 is hollow. For example, the opposite side walls in the cabin 1 are provided with slide grooves along the length direction. Slide blocks matching the slide grooves are provided on both sides of the cell culture tray 22, so that the cell culture tray 22 can slide along the corresponding slide grooves, making it convenient for the cell culture tray 22 to be taken out of the cabin 1 or put into the cabin 1.

[0016] A sliding collection tray 23 is provided inside the cabin 1 along the length direction and below the cell culture tray 22. The collection tray 23 is used to collect debris generated by the cell culture above. For example, slide grooves are provided along the length direction on the opposite side walls of the cabin 1, and sliding blocks matching the slide grooves are provided on both sides of the collection tray 23, so that the collection tray 23 can slide along the corresponding slide grooves, making it convenient for the collection tray 23 to be taken out of the cabin 1 or put into the cabin 1.

[0017] The hatch door 14 is pushed toward the hatch 3, the rotating shaft 12 rotates, the hatch door 14 is closed, the opening of the hatch door 14 is docked with the hatch 3, the opening of the hatch door 14 is accommodated in the three-petal clamp 4, and the rotating rod 9 is rotated. Driven by the forward screw thread and the reverse screw thread, the first petal and the second petal of the three-petal clamp 4 move relatively close to each other to achieve the three-petal clamp 4 clamping the hatch door 14, and the moving block 17 is slightly moved forward. The left limit rod 5 and the right limit rod 6 pass through the long hole 20 of the limit block 19, and the left limit rod 5 is just limited to the left end of the long hole 20 of the limit block, and the right limit rod 6 is just limited to the right end of the long hole 20 of the limit block, thereby realizing the rapid closing of the hatch door 14.

[0018] The moving block 17 is slightly moved backward, and the left limit rod 5 and the right limit rod 6 do not pass through the long hole 20 of the limit block 19. The rotating rod 9 is rotated in the opposite direction. Driven by the forward screw thread and the reverse screw thread, the first petal and the second petal of the three-petal clamp 4 move away from each other, pushing the hatch 14 away from the hatch 3, and the rotating shaft 12 rotates to open the hatch 14, thereby realizing the rapid opening of the hatch 14.

[0019] In this solution, the shape of the left limit rod 5 matches the shape of the left end of the elongated hole 20 of the limit block 19, and the shape of the right limit rod 6 matches the shape of the right end of the elongated hole 20 of the limit block 19, so that the left limit rod 5 and the right limit rod 6 can achieve better limiting with the left and right ends of the elongated hole 20 of the limit block 19.

[0020] In this solution, the three-petal clamp 4 is clamped to the cabin door 14 by rotating the rotating rod 9. Since the left limit rod 5 and the right limit rod 6 on the three-petal clamp 4 are limited in the long hole 20 of the limit block 19, even if the high pressure in the cabin body 1 impacts the three-petal clamp 4, the three-petal clamp 4 under the limiting action will not loosen to the left or right, and can always tightly hold the cabin door 14, so that the cabin door can be tightly locked.

[0021] In this solution, when the hatch 1 needs to be closed, it is only necessary to rotate the rotating rod 9 so that the three-petal clamp 4 clamps the hatch 14, and then slightly move the moving block 17 forward so that the left limit rod 5 and the right limit rod 6 on the three-petal clamp 4 are limited in the long hole 20 of the limit block 19, so that the hatch 14 can be quickly closed. When the hatch 1 needs to be opened, it is only necessary to slightly move the moving block 17 backward so that the left limit rod 5 and the right limit rod 6 are not in the long hole 20 of the limit block 19, and rotate the rotating rod 9 in the opposite direction so that the three-petal clamp 4 releases the hatch 14. The operation is relatively simple, and the hatch can be quickly opened and closed.

[0022] Although the specific embodiments of the present invention are described above, those skilled in the art should understand that these are only examples, and the protection scope of the present invention is defined by the appended claims. Those skilled in the art may make various changes or modifications to these embodiments without departing from the principles and essence of the present invention, but these changes and modifications all fall within the protection scope of the present invention.

Claims

1. A high-pressure cell culture chamber with quick opening and closing functions, characterized in that: The high-pressure cell culture chamber is a horizontal cylindrical single-chamber one-door structure, including a cabin body, one end of the cabin body adopts a standard elliptical head, the other end of the cabin body is sleeved and fixed with a fixed ring frame, and the other end is provided with a hatch, a three-petal clamp is fixed on the fixed ring frame along the edge of the hatch, a left limiting rod is fixed to the top outer side of the first petal of the three-petal clamp, and a right limiting rod is fixed to the top outer side of the second petal relative to the third petal, a left inverted U-shaped moving frame is fixed to the top outer surface of the first petal of the three-petal clamp, and a right inverted U-shaped moving frame is fixed to the top outer surface of the second petal relative to the third petal, a rotating rod is penetrated through the top of the left inverted U-shaped moving frame and the top of the right inverted U-shaped moving frame, the left part of the rotating rod is provided with a forward screw thread, and the right part of the rotating rod is provided with a reverse screw thread, the top of the left inverted U-shaped moving frame is located on the forward screw thread, and the top of the right inverted U-shaped moving frame is located on the reverse screw thread; Two fixed bases are fixed at intervals at the middle position of one side of the fixed ring frame and close to the position of the three-petal clamp, a vertical fixed rod is fixed between the two fixed bases, the upper and lower parts of the vertical fixed rod are respectively sleeved with rotating shafts, the two rotating shafts are fixedly connected to the elliptical cabin door through a connecting block, a fixed column is fixed on the top of the cabin door, a fixed limiting ring is sleeved on the fixed column, a moving block is sleeved on the fixed column, the moving block is limited between the limiting ring and the top of the cabin door, a waist-shaped hole is opened on the moving block so that the moving block can be slightly moved back and forth on the fixed column, a limiting block is fixed on the front end of the moving block, and a long strip hole is opened on the limiting block; The hatch door is pushed toward the hatch direction, the rotating shaft rotates, the hatch door is closed, the hatch opening is docked with the hatch, the hatch opening is accommodated in the three-petal clamp, the rotating rod is rotated, and under the drive of the forward screw thread and the reverse screw thread, the first petal part and the second petal part of the three-petal clamp move relatively close to each other to achieve the three-petal clamp clamping the hatch door, the moving block is slightly moved forward, the left limit rod and the right limit rod pass through the long hole of the limit block, and the left limit rod is just limited to the left end of the long hole of the limit block, and the right limit rod is just limited to the right end of the long hole of the limit block, so as to achieve the rapid closing of the hatch door; The moving block is slightly moved backward, the left limit rod and the right limit rod do not pass through the long strip hole of the limit block, and the rotating rod is rotated in the opposite direction. Driven by the forward screw thread and the reverse screw thread, the first petal part and the second petal part of the three-petal clamp move away from each other in the opposite direction, pushing the hatch door away from the hatch, and the rotating shaft rotates to open the hatch door, thereby realizing the rapid opening of the hatch door; The rotating rod cover is provided with a blind plate cover, the left side of the blind plate cover is sleeved on the left side of the rotating rod, and the right side of the blind plate cover is sleeved on the right side of the rotating rod; A sliding cell culture tray is arranged in the cabin along the length direction, and the cell culture tray is hollow; A sliding collection tray is provided in the cabin along the length direction and below the cell culture tray; The shape of the left limiting rod matches the shape of the left end of the long strip hole of the limiting block, and the shape of the right limiting rod matches the shape of the right end of the long strip hole of the limiting block.

2. The high-pressure cell culture chamber with quick opening and closing functions as claimed in claim 1, characterized in that: The fixing column and the limiting ring are integrally formed.

Citation Information

Patent Citations

  • High-pressure cell incubator, temperature control method and pressure control method thereof

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