The invention discloses an air control pressurization type
cell culture instrument in the technical field of
cell culture instruments. The air control pressurization type
cell culture instrument comprises a culture cabin, a cabin cover and a
pressure detection unit, the cabin cover is provided with a
dynamic pressure simulation module which is used for generating periodic
dynamic pressure for simulating the respiratory
rhythm of a
human body in the culture cabin; in the process of culturing the cells in the
human body, the driving mechanism is used for driving the moving plate, the elastic element and the
piston to reciprocate, the pressure in the culture cabin fluctuates within a certain range, and the periodic change of the in-vivo pressure intensity when the
human body breathes is simulated, so that the cells grow in a state closer to the in-vivo state; a more reliable in-vitro
cell model is provided for subsequent research for revealing physiological and
pathological mechanisms of a human body; and in the culture process, the detection mechanism and the compensation mechanism are used for supplementing or discharging gas into the culture cabin, so that the air pressure change caused by cell
respiration in the culture cabin can be automatically adjusted.