An adjustable multifunctional orthodontic acceleration device for animal experiments

Abstract

The present invention relates to an adjustable multifunctional orthodontic acceleration device for animal experiments, comprising a power integration platform, a motor and a chewing model, wherein lamp beads are pre-embedded on the chewing model, and the power integration platform comprises a power module, a lamp bead driving module, a motor driving module, a matrix keyboard, a single-chip microcomputer, a load module, a debugging module and a single-chip microcomputer peripheral support device; the lamp bead driving module controls the switch state of the lamp bead, the motor driving module adjusts the input voltage of the motor to change the motor speed and thus change the vibration frequency, and the matrix keyboard is divided into an illumination group and a vibration group, which respectively control the lamp bead driving module and the motor driving module; one end of the motor is connected to the power integration platform, and the other end is connected to the chewing model. The present invention can realize the precise irradiation of near-infrared light with adjustable output power and stimulation duration on the orthodontic teeth of experimental animals, and transmit vibrations of different frequencies, can take into account a variety of stimulation modes, adapt to a variety of common experimental animals, and accommodate multiple animals for simultaneous experiments, and can easily convert between multiple parameters, significantly improving experimental efficiency.

Description

Technical field:

[0001] The invention relates to the technical field of experimental equipment, and in particular to an adjustable multifunctional orthodontic acceleration device for animal experiments. Background technology:

[0002] Malocclusion, as one of the three major oral diseases recognized by the World Health Organization, has a global prevalence rate of up to 72.92%, seriously affecting the oral and maxillofacial function, facial beauty, and physical and mental health of patients. It can induce inferiority complex, balance disorders, breathing difficulties, and even endanger life. Orthodontic treatment is an important way to correct malocclusion. However, the course of orthodontic treatment is slow, usually 2-3 years, and even 5-8 years for complex cases. It not only brings long-term uncomfortable treatment experience to patients, but also greatly increases the risk of complications such as enamel demineralization, caries, bone fenestration, and bone cracking. Therefore, how to shorten the course of orthodontic treatment is currently the focus of research for clinicians.

[0003] At present, the methods for accelerating orthodontic tooth movement are divided into surgical treatment and non-surgical treatment. Surgical treatment includes osteotomy, corticotomy, piezoelectric corticotomy, micro-bone surgery, etc., but due to its large trauma, strong pain and high risk, patients generally have low acceptance. Non-surgical treatments include photobiomodulation therapy, ultrasound therapy, vibration therapy, electromagnetic stimulation, local drug injection, etc. Among them, photobiomodulation therapy and vibration therapy have received extensive attention and research due to their low trauma, high safety and strong operability. A large number of cell experiments and animal experiments have confirmed the beneficial effects of both on bone remodeling and bone metabolism. In the relevant research of the patent CN202211031134.0 that the applicant team has been authorized to, it has been proved that photobiomodulation therapy can promote oxidative phosphorylation of periodontal membrane through near-infrared light and accelerate the rate of alveolar bone remodeling. Vibration therapy activates the NF-κB signaling pathway through vibration conduction, upregulates the expression of osteoblast-related factors, promotes alveolar bone remodeling, and shortens the orthodontic treatment time. Although orthodontic acceleration products such as Well Lite, which is mainly based on photobiotherapy, and Acceledent, which is mainly based on vibration, have been launched abroad, their acceleration effects have not been shown to be significant in systematic reviews and meta-analyses. After literature research, we found that the samples included in previous studies were mainly concentrated in adolescent groups, and the application parameters of Well Lite and Acceledent were single. Therefore, we speculate that this controversy about their orthodontic acceleration effects may be related to parameter settings. In summary, the action parameters, effects, and modes of action of photobiomodulation therapy and vibration therapy still need to be further explored in order to shorten the orthodontic course, reduce the incidence of orthodontic complications, and bring better treatment effects and quality of life to patients.

[0004] At present, the research on orthodontic tooth movement is highly dependent on animal experiments. Animal modeling technology mainly simulates tooth movement and alveolar bone reconstruction during human orthodontic treatment by pulling the first molar forward through the orthodontic archwire, mainly with rodents such as mice, rats, and rabbits. However, there are some obvious defects in the current experimental equipment for accelerating orthodontic tooth movement in animals. For example, the patent application number CN202310036655.3 discloses a device for accelerating orthodontic tooth movement in rats, which is provided with a contact head and a vibrator, and the contact head includes a contact head body and a medical elastic material; the bottom of the contact head body is detachably connected to the vibrator, and the contact end of the contact head body is fixedly connected to the medical elastic material, and the medical elastic material is a thermoplastic polyurethane elastomer (TPU). The device can implement vibration intervention on orthodontic teeth and improve the accuracy of vibration acceleration of orthodontic tooth movement experiments in rats. This type of experimental equipment for accelerating orthodontic tooth movement in animals not only has a single stimulation method, but also requires manual hand-held operation, and can only act on a single animal at a time, which greatly limits the scale and efficiency of the experiment. Some experiments even use handheld laser pens or vibration plates used by people in daily life as stimulation sources for animal experiments. The stimulation methods are not accurate enough and the conclusions are questionable. In addition, these devices can only be applied to small animals such as rats and mice, and cannot be applied to more convincing non-rodents such as rabbits, further limiting the breadth and depth of the research. These limitations have led to many problems such as long experiments, high costs, and low efficiency, which has slowed the progress of related research on accelerating orthodontic tooth movement. More importantly, due to the lack of advanced experimental equipment, the comparison and coordinated application of different powers, different vibration frequencies, and different stimulation durations are even more difficult to verify, which has become a major obstacle to breakthroughs in related research on accelerating orthodontic tooth movement. Therefore, we urgently need to develop more advanced research equipment to optimize experimental design and improve research efficiency to fill the gap in this field. Summary of the invention:

[0005] 1. Technical issues to be solved

[0006] The present invention aims to provide an adjustable multifunctional orthodontic acceleration device for animal experiments, which can be widely used in various animal models such as rats, mice, rabbits, etc., to solve the problems existing in the prior art of orthodontic acceleration experiments, such as long time consumption, poor precision, high cost, difficulty in accurately adjusting the action parameters such as light power, vibration frequency, stimulation time, and difficulty in comparing the therapeutic effects of the coordinated application of light and vibration with different parameters.

[0007] (II) Technical solution

[0008] In order to solve the above technical problems, the present invention adopts the following technical solutions: an adjustable multifunctional orthodontic acceleration device for animal experiments, comprising a power integration platform, a motor and a chew model, wherein lamp beads are pre-embedded on the chew model, and the power integration platform comprises a power supply module, a lamp bead driving module, a motor driving module, a matrix keyboard, a single-chip microcomputer, a load module, a debugging module and a single-chip microcomputer peripheral support device; one end of the motor is connected to the power integration platform, and the other end is connected to the chew model, the lamp bead driving module controls the switching state of the lamp beads pre-embedded on the chew model, the motor driving module adjusts the input voltage of the motor to change the motor speed, and then changes the vibration frequency, the matrix keyboard is divided into an illumination group and a vibration group, after the button of the illumination group is pressed, the lamp beads The driving module processes, and the lamp beads on the chew model light up; the vibration group on the matrix keyboard is used to control the motor driving module, and then control the motor to induce low-frequency vibration, which is transmitted to the chew model; the matrix keyboard, the single-chip microcomputer, the lamp bead driving module and the motor driving module, the motor, and the load module are electrically connected to form a working link; with the support of the single-chip microcomputer peripheral support device, instructions are sent through the matrix keyboard, and the single-chip microcomputer receives and processes them, and then passes the instructions to the lamp bead driving module and the motor driving module; the load module is used to pass instructions to the chew model to realize the combination of different power photobiotherapy, different frequency vibration therapy and different stimulation time; the debugging module is used for connection debugging.

[0009] The power integration platform includes a power module, a lamp bead drive module, a motor drive module, a matrix keyboard, a single-chip microcomputer, a load module, a debugging module, a single-chip microcomputer peripheral support device and a motor. Among them, the power module can realize the multi-channel power supply function, ensure that the current and voltage of each channel are maintained within the appropriate range, and optimize the overall power consumption performance.

[0010] The lamp bead driving module is used to accurately control the switching state of the lamp beads embedded in the chewing gum model. By adding boost and buck chips in the circuit design, a constant voltage is ensured to output to meet the requirements of the lamp beads releasing lasers of various parameters. Not only can the lamp bead parameters be adjusted by voltage, but also the optimal lamp bead parameter requirements of 810nm wavelength and 100mW power can be met.

[0011] The motor drive module is responsible for adjusting the input voltage to change the motor speed and thus the vibration frequency.

[0012] The matrix keyboard is divided into an illumination group and a vibration group. When the illumination group button is pressed, the lamp bead drive module is activated, and the near-infrared lamp beads on the chewing model light up; one end of the motor is connected to the power integration platform, and the other end is connected to the chewing model. The first press of the matrix keyboard vibration group button will start the motor drive module, and then start the motor device, causing low-frequency vibration, which is transmitted to the chewing model. When the vibration group button is pressed for the second time, the vibration switches to high-frequency vibration. At the same time, the lamp bead parameters and vibration frequency can be further adjusted by the potentiometer.

[0013] The matrix keyboard, the single-chip microcomputer, the lamp bead driving module, the motor driving module, the motor, and the load module are connected to form an efficient working link. With the support of the single-chip microcomputer peripheral device, the matrix keyboard is simply operated to send instructions, and the single-chip microcomputer quickly receives and processes them, and then passes the instructions to the lamp bead driving module and the motor driving module. The load module accurately transmits these instructions to the chewing gum model to achieve the combination of different power photobiotherapy and different frequency vibration therapy, and the duration of each type of stimulation can be freely set according to experimental needs. The debugging module is responsible for connection debugging during the device design process.

[0014] Furthermore, the chew model includes a base and a posterior teeth positioning groove, anterior teeth fixing holes and a motor connector arranged on the base. The lamp beads are attached to both sides of the posterior teeth positioning groove. There are several anterior teeth fixing holes arranged linearly. Several anterior teeth fixing holes correspond to different distances from the anterior teeth to the first molars of animals of different ages. The chew model is L-shaped as a whole. The chew model is customized according to the oral dimensions of animals of different ages and types after multiple sample measurements, and fits the oral morphology of animals of different ages and types. The distance from the incisor to the first molar (orthodontic tooth) can be selected to ensure that the lamp beads are accurately irradiated to both sides of the buccal and palate of the first molar.

[0015] Furthermore, the chew model is provided with an adjustable telescopic part, which is arranged on the base between the posterior teeth positioning groove and the anterior teeth fixing hole, and can adjust the distance between the posterior teeth positioning groove and the anterior teeth fixing hole, and can be adapted to rats, mice, rabbits and other animals with similar tooth shapes, expanding compatibility, and can be used for orthodontic models of various animals. It can also be adjusted at any time for different mandibular sizes of the same animal at different ages, so as to achieve more accurate stimulation and better assist the development of research work. The adjustable telescopic part can adopt a commonly used electrically controlled telescopic rod structure, or a hard bellows structure with certain telescopic properties.

[0016] Furthermore, the power module has a multi-channel power supply function; the USB interface voltage is 5V output, and the voltage is increased from 5V to 12V through a boost chip, with a maximum of 14.4V. The boost chip specifically adopts the U15 chip IP 2326, which supplies power to multiple channels at the same time to prevent the efficiency of the integrated platform from being reduced.

[0017] Furthermore, the lamp bead driving module reduces the voltage to 0.8-3.5V through a step-down chip, specifically a SM8102ABC step-down chip, and outputs a constant voltage to obtain lamp bead lighting parameters of different powers and different durations.

[0018] Furthermore, the lamp bead driving module uses a 3.2V voltage to obtain near-infrared light parameters with a wavelength of 810nm and a power of 50-100mW. The lamp bead driving module receives the microcontroller signal and adjusts the lamp bead state.

[0019] Furthermore, the lamp bead driving module adjusts the lamp bead power through a potentiometer and adjusts the lamp bead illumination time through a timer.

[0020] Furthermore, the motor driving module adjusts the microcontroller source signal through the MOTOR_PWM1 pulse width, changes the duty cycle of the microcontroller signal, adjusts different vibration frequency outputs by adjusting the duty cycle, amplifies the microcontroller source current through the transistor, and adjusts the vibration frequency of high-frequency and low-frequency vibrations.

[0021] Furthermore, the matrix keyboard controls the switches of different channels, the single-chip microcomputer receives and processes signals, the load module is connected to the chewing gum model and transmits signals, and the debugging module and the single-chip microcomputer peripheral support device provide support for design and device use.

[0022] Furthermore, each channel on the power integration platform is provided with a lamp switch, a high-frequency vibration, and a low-frequency vibration indicator light circuit to indicate the device status.

[0023] This device has a multi-channel function and can be equipped with multiple chew models at the same time. The chew models can be made by 3D printing and can be connected to the power integration platform to achieve synchronous operation. The chew model is customized according to the oral dimensions of rats, mice, and rabbits of different ages after multi-sample measurements, and is consistent with the oral morphology of different experimental animals of different ages. The distance from the incisor to the first molar (orthodontic tooth) can be selected to ensure that the lamp beads are accurately irradiated to both sides of the buccal palate of the first molar. In the experiment, there is no need to fix both hands, and it does not affect the normal use of the gas anesthesia mask, which greatly improves the experimental efficiency and significantly reduces labor costs.

[0024] (III) Beneficial effects

[0025] Compared with the prior art, the beneficial effects of the present invention are:

[0026] The present invention is composed of a multi-channel light-vibration dual-effect power integration platform and a 3D printed chewing model adapted to the rat's oral cavity. The device adopts a multi-channel design, and the chewing model design does not affect the use of the experimental gas anesthesia mask, and can accommodate multiple animals for simultaneous experiments. The matrix keyboard in the power integration platform sends instructions to realize vibration and photobiomodulation therapy acting on the experimental animals simultaneously, front and back, or separately. The chewing model can be adjusted to fit the jaw morphology of rats, mice, and rabbits, and realize the precise irradiation of near-infrared light on the buccal and lingual roots of orthodontic teeth. At the same time, the device can use the boost and buck chips to adjust the potentiometer and motor speed, and then adjust the illumination parameters and vibration parameters, realize the conversion of different parameter photobiotherapy and different parameter vibration therapy, and provide convenience for verifying the effect of synergistic application. This not only greatly shortens the experimental cycle, but also effectively controls the experimental cost, significantly improves the experimental efficiency, and breaks through the current scientific research process in the field of oral orthodontics, animal experiments are time-consuming, poor in precision, high in cost, and the action parameters such as light power, vibration frequency, and stimulation time are difficult to accurately adjust, and the efficacy comparison of different parameters of light and vibration synergistic application is difficult.

[0027] (1) The power integration platform provided by the present invention integrates vibration therapy and photobiomodulation therapy, can realize synchronous operation of multiple animals, and does not affect the use of gas anesthesia masks during use. It can also cope with complex experimental verification requirements such as multi-parameter parallel, before-and-after comparison, and independent conduct, greatly saving experimental time, reducing manpower and material resources, and improving experimental efficiency.

[0028] (2) The chewing gum model provided by the present invention adopts a groove design for the posterior teeth to ensure the stability of the posterior teeth. At the same time, by accurately measuring the distance from the incisor to the first molar of multiple animals of different ages and types, three anterior tooth fixing grooves are set, so that researchers do not need to fix the animals with both hands during the experiment, ensuring that the light beads can accurately illuminate the buccal and palatal sides of the animal's first molar (orthodontic tooth), thereby achieving accurate treatment of orthodontic tooth movement.

[0029] (3) The power integration platform provided by the present invention utilizes the IP 2326 chip for voltage boosting and the SM8102ABC chip for voltage reduction. Under the condition that the overall input voltage remains unchanged, the purpose of performing photobiotherapy and vibration therapy simultaneously is achieved by increasing the number of chips in the internal circuit. Moreover, the power of photobiotherapy and the frequency of vibration therapy can be adjusted, and the duration of each type of stimulation can be freely set according to experimental needs.

[0030] (4) In the chewing gum model provided by the present invention, the front teeth fixing groove can be retracted and the back teeth groove can be widened, so that it can be applicable to animals of different ages and types. Description of the drawings:

[0031] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings required for use in the embodiments are briefly introduced below.

[0032] Figure 1 It is a structural schematic diagram of the chewing gum model of the adjustable multifunctional orthodontic acceleration device for animal experiments according to an embodiment of the present invention;

[0033] Figure 2 It is a circuit principle block diagram of an adjustable multifunctional orthodontic acceleration device for animal experiments according to an embodiment of the present invention;

[0034] Figure 3 It is a circuit diagram of the power module of the adjustable multifunctional orthodontic acceleration device for animal experiments according to an embodiment of the present invention;

[0035] Figure 4 It is a circuit diagram of the lamp bead driving module of the adjustable multifunctional orthodontic acceleration device for animal experiments according to an embodiment of the present invention;

[0036] Figure 5 It is a circuit diagram of the motor drive module of the adjustable multifunctional orthodontic acceleration device for animal experiments according to an embodiment of the present invention;

[0037] Figure 6 It is a circuit diagram of the single chip microcomputer of the adjustable multifunctional orthodontic acceleration device for animal experiments according to an embodiment of the present invention;

[0038] Figure 7 It is a circuit diagram of the matrix keyboard of the adjustable multifunctional orthodontic acceleration device for animal experiments according to an embodiment of the present invention;

[0039] Figure 8 It is a circuit diagram of the load module of the adjustable multifunctional orthodontic acceleration device for animal experiments according to an embodiment of the present invention;

[0040] Fig. 9 It is a circuit diagram of the single-chip peripheral support device of the adjustable multifunctional orthodontic acceleration device for animal experiments according to an embodiment of the present invention;

[0041] Fig.10 It is a circuit diagram of the debugging module of the adjustable multifunctional orthodontic acceleration device for animal experiments according to an embodiment of the present invention;

[0042] Fig.11 It is a circuit diagram of the lamp bead switch, high-frequency vibration, and low-frequency vibration indicator light circuits of the adjustable multifunctional orthodontic acceleration device for animal experiments described in an embodiment of the present invention;

[0043] Fig.12It is a schematic structural diagram of the adjustable multifunctional orthodontic acceleration device for animal experiments according to an embodiment of the present invention when in use;

[0044] Fig.13 This is a schematic diagram of the connection relationship when the adjustable multifunctional orthodontic acceleration device for animal experiments according to an embodiment of the present invention is used;

[0045] Fig.14 This is a block diagram of the module connection principle of the adjustable multifunctional orthodontic acceleration device for animal experiments according to an embodiment of the present invention;

[0046] In the figure: 1. chewing gum model; 2. base; 3. posterior teeth positioning groove; 4. anterior teeth fixing hole; 5. motor connector; 6. lamp beads; 7. adjustable telescopic part; 8. reserved position for gas anesthesia mask; 9. power integration platform; 91. power module; 92. lamp bead drive module; 93. motor drive module; 94. matrix keyboard; 95. single chip microcomputer; 96. load module; 97. debugging module; 98. single chip microcomputer peripheral support device; 10. motor; 11. chewing gum model connector; Specific implementation method:

[0047] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the accompanying drawings in the embodiments of the present invention.

[0048] like Figure 1-14The adjustable multifunctional orthodontic acceleration device for animal experiments shown in the figure comprises a power integration platform 9, a motor 10 and a chew model 1, on which a lamp bead 6 is pre-embedded, and the power integration platform 9 comprises a power module 91, a lamp bead driving module 92, a motor driving module 93, a matrix keyboard 94, a single-chip computer 95, a load module 96, a debugging module 97 and a single-chip computer peripheral support device 98; one end of the motor 10 is connected to the power integration platform 9, and the other end is connected to the chew model 1, the lamp bead driving module 92 controls the switching state of the lamp bead 6 pre-embedded on the chew model 1, the motor driving module 93 adjusts the input voltage of the motor 10 to change the speed of the motor 10, and then changes the vibration frequency, and the matrix keyboard 94 is divided into an illumination group and a vibration group, and after pressing the button of the illumination group , the lamp beads 6 on the chew model 1 light up; the vibration group on the matrix keyboard 94 is used to control the motor 10 to induce low-frequency vibration, which is transmitted to the chew model 1; the matrix keyboard 94, the single-chip microcomputer 95, the lamp bead driving module 92 and the motor driving module 93, the motor 10, and the load module 96 are electrically connected to form a working link; with the support of the single-chip microcomputer peripheral support device 98, instructions are sent through the matrix keyboard 94, the single-chip microcomputer 95 receives and processes them, and then transmits the instructions to the lamp bead driving module 92 and the motor driving module 93; the load module 96 is used to transmit instructions to the chew model 1, so as to realize the combination of different power photobiotherapy and different frequency vibration therapy, and the duration of action of various stimuli can be freely set according to experimental needs; the debugging module 97 is used for connection debugging.

[0049] like Figure 1 The chew model 1 includes a base 2 and a posterior teeth positioning groove 3, anterior teeth fixing holes 4 and a motor connector 5 arranged on the base 2. Lamp beads 6 are attached to both sides of the posterior teeth positioning groove 3. There are three anterior teeth fixing holes 4 arranged linearly. The three anterior teeth fixing holes 4 correspond to different distances from the anterior teeth to the first molars of experimental animals of different ages. The chew model 1 is L-shaped as a whole, avoiding the gas anesthesia mask area. The chew model 1 has been customized according to the oral dimensions of animals of different ages and types after multi-sample measurements, and is consistent with the oral morphology of animals of different ages and types to ensure that the lamp beads 6 are accurately irradiated to both sides of the buccal palate of the first molar. In addition, the chew model 1 has a motor connection 5, which is fixed after 180° rotation, and can be used for the upper or lower jaw of experimental animals.

[0050] Preferably, the chewing gum model 1 is provided with an adjustable telescopic part 7, and the adjustable telescopic part 7 is arranged on the base 2 between the posterior teeth positioning groove 3 and the anterior teeth fixing hole 4, so that the distance between the posterior teeth positioning groove 3 and the anterior teeth fixing hole 4 can be adjusted, and it can be adapted to rats, mice, rabbits and other animals with similar tooth shapes, thereby expanding compatibility and being able to use orthodontic models of various animals. Moreover, it can be adjusted at any time for the different sizes of the mandibles of the same animal at different ages, thereby achieving more precise stimulation and better assisting the development of research work.

[0051] like Figure 3 The power module 91 is provided with a ten-channel power supply function; the USB interface voltage is 5V output, and the voltage is increased from 5V to 12V through the U15 chip IP2326, with a maximum of 14.4V, and ten channels are powered at the same time to prevent the efficiency of the integrated platform from being reduced, thereby enhancing the overall power consumption and preventing the wire diameter from being too thick.

[0052] like Figure 4 , the lamp bead driver module 92 steps down the voltage to 0.8-3.5V through the SM8102ABC step-down chip, outputs a constant voltage, and waits for different lamp bead illumination parameters. The voltage can be adjusted by the potentiometer, and after outputting a constant voltage, waits for different lamp bead illumination parameters. It is recommended to use 3.2V to obtain the near-infrared lamp bead illumination parameters with a wavelength of 810nm and a power of 50-100mW. The chip 4 corner EN plays the main function, receives the microcontroller 95 signal, and adjusts the lamp bead 6 state; the 123 corner plays the potentiometer function to adjust the lamp bead 6 parameters.

[0053] like Figure 5 The motor drive module 93 in the power integration platform 9 adjusts the signal from the microcontroller 95 through the pulse width of MOTOR_PWM1. The duty cycle of the signal from the microcontroller 95 is variable, and the duty cycle can be adjusted to adjust the output of different vibration frequencies. The transistor Q1 is responsible for amplifying the current from the microcontroller and adjusting the vibration frequency of high-frequency and low-frequency vibrations.

[0054] like Figure 6 , the matrix keyboard 94 controls the switches of different channels, the single-chip microcomputer 95 receives and processes the signals, the load module 96 is connected to the chewing gum model 1 and transmits the signals, and the debugging module 97 and the single-chip microcomputer peripheral support device 98 provide support for the design and use of the device.

[0055] like Figure 7 The matrix keyboard 94 is divided into a vibration group and an illumination group. When the illumination group keyboard is pressed, the lamp bead driving module 92 is activated, and the lamp beads of the corresponding channel are lit. When the vibration group keyboard is pressed, the motor driving module 93 can be activated. When pressed for the first time, the motor starts low-frequency vibration. When pressed again, the motor vibrates at a high frequency. When pressed for the third time, the vibration stops. The vibration group and the illumination group do not interfere with each other and can be performed simultaneously.

[0056] like Figure 8 The load module 96 connects the power integration platform 9, the motor 10 and the chewing gum model 1 and drives them to work, ensuring that the motor 10 outputs accurately according to the preset speed, and also accurately adjusts the power output of the lamp bead 6 to meet the needs of different experiments or applications.

[0057] like Fig. 9 The single-chip microcomputer peripheral support device 98 provides necessary support and interfaces for the single-chip microcomputer 95, ensuring that the single-chip microcomputer 95 can work stably and reliably.

[0058] like Fig.10 The debugging module is used to debug and test each module of the power integration platform. By connecting to the computer program, it can monitor and control the working status of each module in real time, conveniently optimize and improve the power integration platform, and improve the performance and stability of the system.

[0059] like Fig.11 Each channel on the power integration platform 9 is provided with a lamp switch, a high-frequency vibration, and a low-frequency vibration indicator light circuit to indicate the device status.

[0060] The method of using the adjustable multifunctional orthodontic acceleration device for animal experiments described in the present invention is as follows:

[0061] The chewing model 1 is placed in the oral cavity of the experimental animal, the front teeth are fixed in the front teeth fixing hole 4, the back teeth are placed in the back teeth positioning groove 3, and the two sides of the back teeth are aligned with the lamp beads 6. Multiple experimental animals can be fixed by multiple groups of chewing models 1 at the same time, so as to realize the use of multiple animals for experiments at the same time, effectively improving the experimental efficiency. After the experimental animals are fixed, the matrix keyboard 94 on the power integration platform 9 controls the lamp bead driving module 92 to adjust the illumination parameters of the lamp bead 6 and the vibration parameters of the motor 10. The lamp bead parameters can select the optimal parameters of wavelength 810nm and power 100mW, and other parameters can also be adjusted. The matrix keyboard 94 controls the conversion of the motor low-frequency or high-frequency vibration through the vibration group buttons. The lamp bead parameters and vibration parameters can also be further adjusted through potentiometers and timers. Various experimental parameters including the emitted light power, irradiation time, vibration frequency, vibration time, and the order of stimulation of the two can be set as programs, and can be adjusted at any time according to the needs of the experiment to achieve the organic combination of light biotherapy and vibration therapy with different parameters.

[0062] In summary, the adjustable multifunctional orthodontic acceleration device for animal experiments provided by the present invention solves the problems of long experimental time and high experimental cost required for orthodontic acceleration experiments in the prior art, difficulty in verifying the effects of comparison and coordinated application of multiple parameters, and low efficiency.

[0063] The present invention provides an adjustable multifunctional orthodontic acceleration device for animal experiments. The device consists of a multi-channel optical-vibration dual-effect power integration platform and a 3D printed chewing model adapted to the animal's oral cavity. By simply operating the power integration platform to send instructions, near-infrared light with different parameters can be accurately irradiated on the animal's orthodontic teeth and transmit vibrations of different frequencies. The device adopts a multi-channel design, and its chewing model design does not affect the use of experimental gas anesthesia masks, can accommodate multiple animals for experiments at the same time, does not need to be held, and the stimulation site is accurate, which greatly improves the experimental efficiency. The chewing part of the device can be removed and replaced, and there are three sizes of rats, mice, and rabbits. The chewing design has fixed grooves of different distances, which is suitable for experimental animals of different ages and breeds. This not only greatly shortens the experimental cycle, but also effectively controls the experimental cost. In addition, the device can conveniently convert between multiple modes of action and multiple parameters, and provides convenience for verifying the effect of synergistic application, significantly improving the experimental efficiency. This will provide a powerful tool and medium for more in-depth research on orthodontic accelerators, promote the continuous advancement of orthodontic treatment technology, and bring better treatment effects and quality of life to patients.

[0064] The present invention is described above by way of examples, but the present invention is not limited to the above specific embodiments, and any changes or modifications made based on the present invention belong to the scope of protection claimed by the present invention.

Claims

1. An adjustable multifunctional orthodontic acceleration device for animal experiments, characterized in that: It includes a power integration platform, a motor and a chewing model, wherein the chewing model is pre-embedded with lamp beads, and the power integration platform includes a power module, a lamp bead driving module, a motor driving module, a matrix keyboard, a single-chip microcomputer, a load module, a debugging module and a single-chip microcomputer peripheral support device; One end of the motor is connected to the power integration platform, and the other end is connected to the chew model. The lamp bead driving module controls the switch state of the pre-buried lamp bead on the chew model. The motor driving module adjusts the input voltage of the motor to change the motor speed and thus change the vibration frequency. The matrix keyboard is divided into an illumination group and a vibration group. The illumination group controls the lamp bead on the chew model by controlling the lamp bead driving module; the vibration group on the matrix keyboard is used to control the motor driving module to induce vibration; the matrix keyboard, the single-chip microcomputer, the lamp bead driving module and the motor driving module, the motor, and the load module are electrically connected to form a working link; with the support of the single-chip microcomputer peripheral support device, instructions are sent through the matrix keyboard, the single-chip microcomputer receives and processes, and then transmits the instructions to the lamp bead driving module and the motor driving module; The load module is used to transmit instructions to the chew model, and the debugging module is used for connection and debugging. The chew model includes a base and a posterior teeth positioning groove, a front teeth fixing hole and a motor connector arranged on the base. The lamp beads are attached to both sides of the posterior teeth positioning groove. There are several front teeth fixing holes, which are arranged linearly. Several front teeth fixing holes correspond to different distances from the front teeth to the first molars of animals of different ages. The chew model is L-shaped as a whole. An adjustable telescopic part is provided on the chew model. The adjustable telescopic part is arranged on the base between the posterior teeth positioning groove and the front teeth fixing hole, and can be adjusted according to the tooth sizes of different animals and the different distances from the front teeth to the first molars.

2. The adjustable multifunctional orthodontic acceleration device for animal experiments according to claim 1, characterized in that: The power module has a multi-channel power supply function, outputs a voltage of 5V through a USB interface, increases the voltage from 5V to 12V through a boost chip, and has a maximum output voltage of 14.4V, and can supply power to multiple channels at the same time.

3. The adjustable multifunctional orthodontic acceleration device for animal experiments according to claim 1, characterized in that: The lamp bead driving module reduces the voltage to 0.8-3.5V through a step-down chip, and the lamp bead can emit near-infrared light with different output powers and different stimulation durations by adjusting the potentiometer and the timer.

4. The adjustable multifunctional orthodontic acceleration device for animal experiments according to claim 3, characterized in that: The lamp bead driving module uses a 3.2V voltage to make the lamp bead emit near-infrared light with a wavelength of 810nm and a power of 100mW. The lamp bead driving module adjusts the state of the lamp bead by receiving the microcontroller signal.

5. The adjustable multifunctional orthodontic acceleration device for animal experiments according to claim 4, characterized in that: The lamp bead driving module regulates the input voltage within the range of 0.8-3.5V through a potentiometer to adjust the lamp bead output power and stimulation duration.

6. The adjustable multifunctional orthodontic acceleration device for animal experiments according to claim 1, characterized in that: The motor driving module adjusts the single-chip source signal through pulse width, changes the duty cycle of the single-chip signal, adjusts different vibration frequency outputs by adjusting the duty cycle, amplifies the single-chip source current through transistors, and adjusts the vibration frequency.

7. The adjustable multifunctional orthodontic acceleration device for animal experiments according to claim 1, characterized in that: The matrix keyboard controls the switches of different channels, the single-chip microcomputer receives and processes signals, the load module is connected to the chewing gum model and transmits signals, and the debugging module and the single-chip microcomputer peripheral support device provide support for the use of the device.

8. The adjustable multifunctional orthodontic acceleration device for animal experiments according to claim 1, characterized in that: The power integration platform is provided with a lamp bead switch, a high-frequency vibration indicator light, and a low-frequency vibration indicator light circuit.

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