A kind of medical disposable self-adhesive dressing and its manufacturing method

By introducing drug injection module and drug storage module into medical disposable self-adhesive dressings, combining polymer fiber mesh layer and antibacterial coating, the problems of inconvenience of drug delivery and unstable release are solved, and the precise injection of drugs and Continuous release reduces the risk of infection and improves treatment effectiveness and comfort.

CN118750270BActive Publication Date: 2024-12-31JIANGSU JINYOU MEDICAL TECHNOLOGY CO LTD
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Patent Information

Application Number
CN202411080157.X
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-08-07
Publication Date
2024-12-31
Estimated Expiration
2044-08-07

AI Technical Summary

Technical Problem

The existing medical self-adhesive dressings lack flexibility in drug administration, resulting in frequent replacement of dressings by patients, increasing the risk of infection, and complex operation, unstable drug release, cumbersome treatment process, and low patient comfort.

Method used

A medical disposable self-adhesive dressing is designed, including a drug injection module and a drug storage module, using a medical silicone injection layer and a polyvinyl alcohol storage capsule to achieve accurate injection and continuous release of drugs, combining polymer fiber mesh layer and antibacterial Coating, enhances antibacterial and water absorption, isolates wound exudate, and improves the mechanical strength and breathability of the dressing through a multi-layer structure.

Benefits of technology

It reduces the risk of wound infection in patients, simplifies the drug administration process, extends the service life of the dressing, improves the treatment effect and patient comfort, and reduces the complexity of the treatment process and waste of resources.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses a medical disposable self-adhesive dressing and a manufacturing method thereof, which relates to the technical field of medical self-adhesive dressings, and comprises a self-adhesive dressing base layer, wherein a drug injection module and a drug storage module are installed inside the self-adhesive dressing base layer, wherein the drug injection module comprises a medical silicone injection layer installed inside the self-adhesive dressing base layer, wherein a medical silicone injection protective layer is installed at the bottom of the medical silicone injection layer, wherein a connecting cover is installed at the bottom of the self-adhesive dressing base layer, wherein a movable cover is installed at one side of the connecting cover, and wherein a peeling label is installed at one end of the movable cover. The present invention is provided with a drug injection module, wherein the drug injection module comprises a self-adhesive dressing base layer, a medical silicone injection layer, a medical silicone injection protective layer, a connecting cover, a movable cover, a peeling label and a re-adhesive coating, and wherein the built-in medical silicone injection layer allows drugs to be directly and accurately injected into the medical disposable self-adhesive dressing, thereby solving the problems of inconvenient drug administration and high infection risk during wound care for patients.
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Description

Technical Field

[0001] The invention relates to the technical field of medical self-adhesive dressings, in particular to a disposable medical self-adhesive dressing and a manufacturing method thereof. Background Art

[0002] Traditional medical self-adhesive dressings have limitations in the wound care process and lack flexibility in drug administration. Patients are required to change dressings frequently, which increases the risk of infection. The medical self-adhesive dressing of the present application can solve the problems of inconvenient drug administration, high risk of infection and complex operation during patient wound care by installing a drug injection module.

[0003] The defects of existing medical self-adhesive dressings are:

[0004] 1. Patent document US10758422B1 discloses a medical dressing system, which mainly considers how to improve the problem of wound compression, but does not consider how to solve the problems of inconvenience in drug administration, high risk of infection and complicated operation during wound care for patients;

[0005] 2. Patent document JP6334678B2 discloses a medical dressing, which mainly considers how to increase the effect of the initial release of the drug active agent, but does not consider how to solve the problems of unstable drug release, cumbersome treatment process and low patient comfort of the disposable medical self-adhesive dressing;

[0006] 3. Patent document US10980674B2 discloses a medical dressing, which mainly considers the problem of how to prevent pressure sores, but does not consider how to absorb wound exudate, enhance antibacterial ability to prevent infection, isolate and protect, and promote wound healing;

[0007] 4. Patent document CN102872368B discloses a Chinese medicine patch preparation for purging fire and detoxifying. The document mainly considers how to relieve various discomfort symptoms caused by inflammation, but does not consider how to enhance the multifunctionality of the dressing, improve the antibacterial and antistatic properties, and extend the service life of the self-adhesive dressing; Summary of the invention

[0008] The object of the present invention is to provide a medical disposable self-adhesive dressing and a manufacturing method thereof, so as to solve the problems raised in the above background technology.

[0009] To achieve the above object, the present invention provides the following technical solution: a medical disposable self-adhesive dressing, comprising a self-adhesive dressing base layer, a drug injection module and a drug storage module are installed inside the self-adhesive dressing base layer, and the drug storage module is located above the drug injection module, the drug injection module is used to inject dressing drugs into the drug storage module, and the drug storage module is used to store dressing drugs;

[0010] The drug injection module comprises a medical silicone injection layer installed inside the self-adhesive dressing base layer, a medical silicone injection protective layer is installed at the bottom of the medical silicone injection layer, and the medical silicone injection protective layer is located at the bottom of the self-adhesive dressing base layer;

[0011] A connecting cover is installed at the bottom of the self-adhesive dressing base layer, and the connecting cover is located on one side of the medical silicone injection protective layer. A movable cover is installed on one side of the connecting cover, and the movable cover is located at the bottom of the medical silicone injection protective layer. A peeling label is installed at one end of the movable cover.

[0012] The top of the movable cover and the bottom of the self-adhesive dressing base layer are both provided with a re-adhesive coating, and the re-adhesive coating is used for repeatedly sticking the movable cover.

[0013] Preferably, the drug storage module comprises a thick absorbent cotton layer embedded in the self-adhesive dressing base layer, a polymer fiber mesh layer is arranged on the top of the thick absorbent cotton layer, and an antibacterial coating is applied on the surface of the polymer fiber mesh layer, and the antibacterial coating is one or more of antibacterial peptides, nanosilver, chitosan and tea polyphenols.

[0014] Preferably, a polyvinyl alcohol drug storage bag is provided inside the thick absorbent cotton layer, and the polyvinyl alcohol drug storage bag is located above the self-adhesive dressing base layer. The top of the polyvinyl alcohol drug storage bag is provided with evenly arranged release micropores, and the release micropores are used to release the drug injected inside the polyvinyl alcohol drug storage bag.

[0015] Preferably, the inner surface of the polyvinyl alcohol drug storage capsule is coated with a thermosensitive hydrogel, and the model of the thermosensitive hydrogel is Pluronic F modified thermosensitive hydrogel.

[0016] Preferably, an isolation layer is provided at the bottom of the thick absorbent cotton layer, the isolation layer is used to isolate wound exudate, and evenly arranged airflow tubes are provided inside the thick absorbent cotton layer, the airflow tubes are used to guide wound exudate and air to flow to the thick absorbent cotton layer.

[0017] Preferably, the self-adhesive dressing base layer comprises a polyester fiber base material, a polypropylene fiber layer, a viscose fiber layer, a cotton fiber layer, an antibacterial coating and a graphene antistatic coating;

[0018] The top of the polyester fiber substrate is connected to a polypropylene fiber layer, the top of the polypropylene fiber layer is connected to a viscose fiber layer, the top of the viscose fiber layer is connected to a cotton fiber layer, the surfaces of the polypropylene fiber layer, the viscose fiber layer and the cotton fiber layer are all coated with an antibacterial coating, and the surface of the antibacterial coating is coated with a graphene antistatic coating.

[0019] Preferably, the antibacterial coating is one or more of a silver ion coating, a nanosilver coating and a chitosan coating.

[0020] Preferably, a medical pressure-sensitive adhesive layer is provided on the top of the self-adhesive dressing base layer, and the medical pressure-sensitive adhesive layer is located on the outside of the thick absorbent cotton layer;

[0021] The top of the medical pressure-sensitive adhesive layer is connected with symmetrically arranged release paper, the top of the release paper is provided with a peeling aid, the top of the peeling aid is connected with a peeling layer, and the back of the peeling layer is provided with a peeling label 2.

[0022] Preferably, the manufacturing method of the medical disposable self-adhesive dressing is as follows:

[0023] S1. Prepare a self-adhesive dressing base layer;

[0024] S2. Prepare and install a drug injection module;

[0025] S3, preparing and installing a drug storage module;

[0026] S4. Perform surface treatment.

[0027] Preferably, in S1, the following steps are also included:

[0028] S11, uniformly coating the antibacterial coating on the surfaces of the polypropylene fiber layer, the viscose fiber layer and the cotton fiber layer, and coating the graphene antistatic coating on the surface of the antibacterial coating;

[0029] S12, stacking the polyester fiber substrate, the polypropylene fiber layer, the viscose fiber layer, and the cotton fiber layer in sequence and hot-pressing and bonding them;

[0030] In S2, the following steps are also included:

[0031] S21, injection molding the medical silicone into a medical silicone injection layer, pasting a medical silicone injection protective layer on the bottom of the medical silicone injection layer, and embedding the medical silicone injection layer into the self-adhesive dressing base layer and fixing it;

[0032] S22, a connection cover is fixedly installed at the bottom of the self-adhesive dressing base layer, a movable cover is installed on one side of the connection cover, and one end of the movable cover is connected to a peel-off label 1;

[0033] In S3, the following steps are also included:

[0034] S31, combining the thick absorbent cotton layer with the polymer fiber mesh layer, and applying an antibacterial coating on the surface of the polymer fiber mesh layer;

[0035] S32, coating the inner surface of the polyvinyl alcohol drug storage capsule with a thermosensitive hydrogel, and opening evenly distributed release micropores on the top, and embedding the polyvinyl alcohol drug storage capsule into a thick layer of absorbent cotton;

[0036] S33, laying an isolation layer at the bottom of the thick water-absorbing cotton layer, and evenly opening airflow pipes inside the thick water-absorbing cotton layer;

[0037] In S4, the following steps are also included:

[0038] S41. A medical pressure-sensitive adhesive layer is applied on top of the thick absorbent cotton layer, and symmetrically arranged release papers are attached on top of the medical pressure-sensitive adhesive layer. A peeling aid is applied on the top of the release paper and covers the peeling layer, and a peeling label 2 is connected to the back of the peeling layer.

[0039] Compared with the prior art, the present invention has the following beneficial effects:

[0040] 1. The present invention is equipped with a drug injection module, which includes a self-adhesive dressing base, a medical silicone injection layer, a medical silicone injection protective layer, a connecting cover, a movable cover, a peeling label and a re-adhesive coating. Through the built-in medical silicone injection layer, the medical disposable self-adhesive dressing allows the drug to be directly and accurately injected into the medical disposable self-adhesive dressing, and there is no need to tear off the medical disposable self-adhesive dressing for drug injection, thereby reducing the risk of wound infection in patients. The setting of the medical silicone injection protective layer effectively protects the injection site, prevents external contamination and bacterial invasion, and ensures the sterility and safety of the injection process. At the same time, the design of the connecting cover and the movable cover makes the drug injection process more convenient, and medical staff can easily inject the drug. The movable cover is opened for injection. After the injection, the movable cover is re-adhered to the self-adhesive dressing base layer through the re-adhesive coating, so as to maintain the integrity and sealing of the disposable medical self-adhesive dressing, and also facilitate subsequent re-injection or inspection, thereby improving the reusability of the disposable medical self-adhesive dressing and reducing the waste of medical resources. Patients do not need to frequently change the disposable medical self-adhesive dressing or receive multiple injections, thereby reducing discomfort and anxiety during treatment and improving the comfort of patients. The setting of the peeling label makes it easier to open the movable cover, and medical staff can complete the injection operation quickly and accurately, thereby improving work efficiency. Therefore, the problems of inconvenient drug administration, high risk of infection and complicated operation during wound care for patients can be solved.

[0041] 2. The present invention is equipped with a drug storage module, which includes a thick absorbent cotton layer, a polymer fiber mesh layer, an antibacterial coating, a polyvinyl alcohol drug storage capsule, release micropores and a thermosensitive hydrogel. The thick absorbent cotton layer serves as a storage carrier for drugs and not only has good water absorption performance but also can effectively protect the drugs from the influence of the external environment. The polymer fiber mesh layer and the antibacterial coating on its surface further enhance the antibacterial performance of the dressing and reduce the risk of infection. At the same time, traditional wound care or treatment requires multiple administrations at different time points, which increases the burden on patients and causes unstable drug concentration in the wound area. Through the polyvinyl alcohol drug storage capsule and the release micropores on its top, the medical disposable self-adhesive dressing can achieve continuous and controllable drug release, ensuring that the wound area can maintain an effective drug concentration for a period of time, thereby improving the treatment effect. Langnick Pluronic F127 modified thermosensitive hydrogel gives the dressing the ability of intelligent responsive drug release, and can adjust the drug release rate according to the temperature changes in the wound area, thereby increasing or decreasing the amount of drug released when needed, improving the targetedness and effectiveness of treatment. Since the drug can be released continuously and controllably, patients do not need to change dressings frequently or receive additional treatments, thereby improving patient comfort. Medical staff only need to inject the drug into the polyvinyl alcohol reservoir during the first use, and then the medical disposable self-adhesive dressing can automatically complete the drug release process without multiple interventions. Drugs can also be added through the drug injection module during the use of the medical disposable self-adhesive dressing, which greatly simplifies the treatment process and reduces the workload of medical staff. Therefore, it can solve the problems of unstable drug release, cumbersome treatment process and low patient comfort of medical disposable self-adhesive dressings.

[0042] 3. The present invention is equipped with a thick absorbent cotton layer, a polymer fiber mesh layer, an antibacterial coating, an isolation layer and an airflow tube. The thick absorbent cotton layer has excellent water absorption performance, can quickly and massively absorb the exudate generated by the wound, keep the wound dry, and reduce the risk of infection caused by a humid environment. The polymer fiber mesh layer not only helps to enhance the overall structural strength of the dressing, but also promotes the air permeability and microcirculation of the wound through its microporous structure, providing a more suitable healing environment for the wound. The application of the antibacterial coating can effectively inhibit the growth of bacteria and fungi, reduce the risk of wound infection, and accelerate the wound healing process. The isolation layer is provided with It effectively isolates wound exudate from the external environment, prevents wound exudate from contaminating clothing or bed sheets, and also reduces the chance of external pollutants contacting the wound, further ensuring the cleanliness and safety of the wound. The airflow tube arranged inside the thick absorbent cotton layer guides the wound exudate to flow to the thick absorbent cotton layer, and promotes air circulation to a certain extent, reduces the humidity in the wound area, helps prevent the growth of anaerobic bacteria, and promotes the drying and healing of the wound. The comfort and ease of use of the medical disposable self-adhesive dressing are considered as a whole, so it can solve the problems of absorbing wound exudate, enhancing antibacterial ability to prevent infection, isolating and protecting, and promoting wound healing.

[0043] 4. The present invention sets a multi-layer structure of a self-adhesive dressing base layer, which includes a polyester fiber substrate, a polypropylene fiber layer, a viscose fiber layer, a cotton fiber layer, an antibacterial coating and a graphene antistatic coating. The multi-layer structure of the self-adhesive dressing base layer not only provides good mechanical strength and flexibility, but also achieves better adaptability and air permeability to the wound through the combination of different fiber layers, which helps to keep the wound dry and clean and promote wound healing. The antibacterial coating is applied on the surface of the polypropylene fiber layer, the viscose fiber layer and the cotton fiber layer, which significantly enhances the antibacterial performance of the dressing. The antibacterial coating can effectively inhibit the growth of microorganisms such as bacteria and fungi, reduce the risk of wound infection, and provide a safer and more hygienic healing environment for the wound. The graphene antistatic coating solves the problem of disposable medical self-adhesive dressings. The static electricity problem generated by the material during use can be effectively eliminated, ensuring the stability and safety of the medical disposable self-adhesive dressing during use. The combination of multi-layer fiber structure and antibacterial coating makes the medical disposable self-adhesive dressing softer and more breathable, reducing friction and discomfort with the wound. At the same time, the improvement of antibacterial properties also reduces pain and inflammation caused by infection, further improving the patient's comfort. Due to the protection of the antibacterial coating and antistatic coating, the medical disposable self-adhesive dressing can stay clean and dry for a longer time, reducing the frequency of replacement due to contamination or static electricity, thereby extending the service life of the medical disposable self-adhesive dressing. Therefore, it can solve the problem of how to enhance the versatility of the dressing, improve the antibacterial and antistatic properties, and extend the service life of the self-adhesive dressing. BRIEF DESCRIPTION OF THE DRAWINGS

[0044] Figure 1 It is an overall schematic diagram of the present invention;

[0045] Figure 2 It is a side structural schematic diagram of the present invention;

[0046] Figure 3 It is a schematic diagram of the cross-sectional structure of the present invention;

[0047] Figure 4 This is a schematic diagram of the structure of the drug injection module of the present invention;

[0048] Figure 5 This is a schematic diagram of the structure of the drug storage module of the present invention;

[0049] Figure 6 The manufacturing method flow chart of the present invention.

[0050] In the figure: 1. Self-adhesive dressing base layer; 2. Medical silicone injection layer; 3. Medical silicone injection protective layer; 4. Connecting cover; 5. Movable cover; 6. Peel-off label 1; 7. Re-adhesive coating; 8. Thick absorbent cotton layer; 9. Polymer fiber mesh layer; 10. Polyvinyl alcohol drug storage capsule; 11. Release micropores; 12. Medical pressure-sensitive adhesive layer; 13. Release paper; 14. Peel-off layer; 15. Peel-off label 2; 16. Isolation layer; 17. Airflow tube. DETAILED DESCRIPTION

[0051] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0052] In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front end", "rear end", "two ends", "one end", "the other end" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0053] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "provided with", "connected", etc. should be understood in a broad sense. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0054] See also Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 6 , an embodiment provided by the present invention: a medical disposable self-adhesive dressing, comprising a self-adhesive dressing base layer 1, a drug injection module and a drug storage module are installed inside the self-adhesive dressing base layer 1, and the drug storage module is located above the drug injection module, the drug injection module is used to inject dressing drugs into the drug storage module, and the drug storage module is used to store dressing drugs;

[0055] The drug injection module comprises a medical silicone injection layer 2 installed inside the self-adhesive dressing base layer 1, a medical silicone injection protective layer 3 is installed at the bottom of the medical silicone injection layer 2, and the medical silicone injection protective layer 3 is located at the bottom of the self-adhesive dressing base layer 1;

[0056] A connection cover 4 is installed at the bottom of the self-adhesive dressing base layer 1, and the connection cover 4 is located on one side of the medical silicone injection protective layer 3. A movable cover 5 is installed on one side of the connection cover 4, and the movable cover 5 is located at the bottom of the medical silicone injection protective layer 3. A peeling label 6 is installed at one end of the movable cover 5;

[0057] The top of the movable cover 5 and the bottom of the self-adhesive dressing base layer 1 are both provided with a re-adhesive coating 7, and the re-adhesive coating 7 is used for repeatedly sticking the movable cover 5.

[0058] Furthermore, the self-adhesive dressing base layer 1 is the main bearing part of the medical disposable self-adhesive dressing. The medical silicone injection layer 2 is embedded in the self-adhesive dressing base layer 1 and is made of medical grade silicone. It has excellent elasticity and sealing properties and is used to store and slowly release drugs. The silicone material has high safety and will not have adverse reactions with drugs. It can maintain the stability and activity of drugs for a long time. The medical silicone injection protective layer 3 is located below the medical silicone injection layer to protect the medical silicone injection layer 2 from external pollution and physical damage, while ensuring the safety of the drug during the injection process.

[0059] The connecting cover 4 is fixed to the bottom of the self-adhesive dressing base layer 1, adjacent to the medical silicone injection protective layer 3, and is used to connect and fix the movable cover 5 to ensure the stability and sealing of the overall structure. The movable cover 5 is designed to be openable and closable, so that medical staff can open the movable cover 5 to inject or supplement the medical silicone injection layer 2 without removing the entire medical disposable self-adhesive dressing. A peeling label 6 is provided at one end of the movable cover 5 to facilitate medical staff to easily open and reseal;

[0060] The re-adhesive coating 7 is coated on the top of the movable cover 5 and the bottom of the self-adhesive dressing base layer 1, and is made of a re-adhesive material, ensuring that the movable cover 5 can still be tightly adhered to the self-adhesive dressing base layer 1 after multiple openings and closings, maintaining the overall sealing and integrity, improving the convenience of use of the medical disposable self-adhesive dressing, and extending the service life of the medical disposable self-adhesive dressing.

[0061] See also Figure 5 An embodiment of the present invention is: a medical disposable self-adhesive dressing, wherein the drug storage module comprises a thick absorbent cotton layer 8 embedded in a self-adhesive dressing base layer 1, a polymer fiber mesh layer 9 is arranged on the top of the thick absorbent cotton layer 8, and an antibacterial coating is applied on the surface of the polymer fiber mesh layer 9, and the antibacterial coating is one or more of antibacterial peptides, nanosilver, chitosan and tea polyphenols.

[0062] Furthermore, the thick absorbent cotton layer 8 is embedded in the base layer of the self-adhesive dressing, has excellent water absorption performance, can quickly absorb wound exudate, keep the wound dry, and promote healing. The thick absorbent cotton layer 8 also takes into account the storage and sustained release of drugs, and provides a stable environment for the drugs. The polymer fiber mesh layer 9 covers the thick absorbent cotton layer 8 and is woven from polymer fiber materials to form a mesh structure, which not only enhances the air permeability and comfort of the medical disposable self-adhesive dressing, but also improves the uniformity of drug distribution;

[0063] The antibacterial coating is applied on the surface of the polymer fiber mesh layer 9, and is composed of one or more components of antibacterial peptides, nanosilver, chitosan and tea polyphenols, which can effectively inhibit the growth of bacteria and fungi. At the same time, multiple components work synergistically to provide a broad-spectrum antibacterial effect and reduce the risk of wound infection. The presence of the antibacterial coating enables the medical disposable self-adhesive dressing to continue to exert antibacterial effects while absorbing wound exudate, providing a clean and safe healing environment for the wound.

[0064] See also Figure 3 and Figure 5The present invention provides an embodiment: a medical disposable self-adhesive dressing, wherein a polyvinyl alcohol drug storage bag 10 is arranged inside the thick absorbent cotton layer 8, and the polyvinyl alcohol drug storage bag 10 is located above the self-adhesive dressing base layer 1, and the top of the polyvinyl alcohol drug storage bag 10 is provided with evenly arranged release micropores 11, and the release micropores 11 are used to release the drug injected into the polyvinyl alcohol drug storage bag 10.

[0065] Furthermore, the polyvinyl alcohol drug storage capsule 10 is located inside the thick absorbent cotton layer 8 and close to the top of the self-adhesive dressing base layer 1. Polyvinyl alcohol is a polymer material with good biocompatibility and no toxic side effects. The polyvinyl alcohol drug storage capsule 10 is made of polyvinyl alcohol and can safely store drugs and maintain their stability. Release micropores 11 are evenly arranged on the top of the polyvinyl alcohol drug storage capsule 10. The release micropores 11 are channels for drug release. After the drug is injected into the polyvinyl alcohol drug storage capsule 10, it will be slowly released to the wound area at a controllable speed through the release micropores 11, thereby achieving continuous drug administration, helping to maintain the local drug concentration in the wound and improving the treatment effect.

[0066] See also Figure 3 and Figure 5 An embodiment of the present invention is a medical disposable self-adhesive dressing, wherein the inner surface of the polyvinyl alcohol drug storage bag 10 is coated with a thermosensitive hydrogel, and the model of the thermosensitive hydrogel is Pluronic F127 modified thermosensitive hydrogel.

[0067] Furthermore, the aqueous solution of the Pluronic F127 modified thermosensitive hydrogel is in a flowing state at low temperatures, and undergoes a phase change when it is close to body temperature, from a liquid state to a semi-solid or solid gel. This property enables the Pluronic F127 modified thermosensitive hydrogel coated on the inner surface of the polyvinyl alcohol drug storage bag 10 to adjust its physical state according to the temperature change around the wound, thereby affecting the release rate of the drug;

[0068] During the phase change process of Pluronic F127 modified thermosensitive hydrogel, the change in its network structure will change the diffusion rate of drug molecules in it. Therefore, by precisely controlling the phase change temperature of the hydrogel, the intelligent regulation of the drug release rate can be achieved. When the temperature around the wound rises to close to body temperature, the hydrogel undergoes a phase change and the drug release rate accelerates, otherwise it slows down. This intelligent controlled release mechanism helps to maintain the local drug concentration in the wound within the optimal range and improve the therapeutic effect.

[0069] See also Figure 3 and Figure 5An embodiment of the present invention is a medical disposable self-adhesive dressing, wherein an isolation layer 16 is provided at the bottom of the thick absorbent cotton layer 8, and the isolation layer 16 is used to isolate wound exudate. The inside of the thick absorbent cotton layer 8 is provided with evenly arranged airflow tubes 17, and the airflow tubes 17 are used to guide wound exudate and air to flow to the thick absorbent cotton layer 8.

[0070] Furthermore, wounds often produce exudate during the healing process. If the wound exudate is not effectively managed, it will increase the risk of infection and also affect the patient's comfort. The thick absorbent cotton layer 8 can efficiently absorb the wound exudate and keep the wound area dry, while the isolation layer 16 further ensures that the wound exudate will not penetrate the outside of the disposable medical self-adhesive dressing and contaminate clothing or bed sheets, while also reducing the chance of external contaminants contacting the wound.

[0071] The main function of the thick absorbent cotton layer 8 is to absorb exudate. The airflow tube 17 arranged inside promotes air circulation to a certain extent, guides air to circulate inside the medical disposable self-adhesive dressing, reduces the humidity in the wound area, reduces the risk of anaerobic bacteria growth, and also helps the ventilation and microcirculation of the wound, providing a more suitable environment for the wound to heal;

[0072] Through the synergistic effect of the isolation layer 16 and the thick absorbent cotton layer 8, as well as the presence of the antibacterial coating, the risk of wound infection is significantly reduced. The isolation layer 16 prevents the spread of exudate, while the thick absorbent cotton layer 8 quickly absorbs and locks the exudate, reducing the environment for bacterial growth.

[0073] See also Figure 1 , Figure 2 and Figure 3 , an embodiment provided by the present invention: a medical disposable self-adhesive dressing, wherein the self-adhesive dressing base layer 1 comprises a polyester fiber base material, a polypropylene fiber layer, a viscose fiber layer, a cotton fiber layer, an antibacterial coating and a graphene antistatic coating;

[0074] The top of the polyester fiber substrate is connected to a polypropylene fiber layer, the top of the polypropylene fiber layer is connected to a viscose fiber layer, the top of the viscose fiber layer is connected to a cotton fiber layer, the surfaces of the polypropylene fiber layer, the viscose fiber layer and the cotton fiber layer are all coated with an antibacterial coating, and the surface of the antibacterial coating is coated with a graphene antistatic coating.

[0075] Furthermore, the polyester fiber substrate is used as the bottom layer of the disposable medical self-adhesive dressing. The polyester fiber substrate provides good mechanical strength and stability, ensuring that the disposable medical self-adhesive dressing is not easily deformed or damaged during use. The chemical resistance and wrinkle resistance of the polyester fiber substrate also increase the service life of the disposable medical self-adhesive dressing.

[0076] The polypropylene fiber layer is connected to the top of the polyester fiber substrate. The polypropylene fiber layer has good air permeability and moisture absorption, which helps to maintain a dry environment around the wound and reduce the possibility of bacterial growth. At the same time, the polypropylene fiber also has a certain degree of softness, which improves the comfort of the medical disposable self-adhesive dressing.

[0077] The viscose fiber layer is located on the polypropylene fiber layer. The viscose fiber layer has excellent moisture absorption and air permeability, and can further absorb wound exudate to keep the wound clean. The viscose fiber also has good skin-affinity, reducing irritation to the patient's skin.

[0078] As the layer closest to the wound, the cotton fiber layer provides the best comfort experience for patients with its natural, soft and breathable properties. Cotton fiber can also effectively absorb and lock exudate to prevent it from spreading to the surrounding skin.

[0079] The antibacterial coating is applied on the surface of the polypropylene fiber layer, the viscose fiber layer and the cotton fiber layer. The antibacterial coating can effectively inhibit the growth of bacteria and fungi and reduce the risk of wound infection. The graphene antistatic coating is applied on the surface of the antibacterial coating. The graphene antistatic coating can effectively prevent the generation and accumulation of static electricity and reduce patient discomfort caused by static electricity.

[0080] See also Figure 1 , Figure 2 and Figure 3 , an embodiment provided by the present invention: a medical disposable self-adhesive dressing, wherein the antibacterial coating is one or more of a silver ion coating, a nanosilver coating and a chitosan coating.

[0081] Furthermore, the antibacterial coating adopts one or more combinations of silver ion coating, nanosilver coating and chitosan coating. The antibacterial coatings have excellent antibacterial properties, can effectively inhibit the growth of bacteria and fungi, and reduce the risk of wound infection; the silver ions in the silver ion coating have broad-spectrum antibacterial properties, can destroy the cell walls and cell membranes of bacteria, thereby killing the bacteria; the nanosilver in the nanosilver coating has a larger specific surface area, a more significant antibacterial effect, and a smaller amount is used, reducing the potential impact on the human body; the chitosan in the chitosan coating is a natural high molecular polysaccharide with good biocompatibility and antibacterial properties, and can promote wound healing.

[0082] See also Figure 1 , Figure 2 and Figure 3 , an embodiment provided by the present invention: a medical disposable self-adhesive dressing, wherein a medical pressure-sensitive adhesive layer 12 is provided on the top of the self-adhesive dressing base layer 1, and the medical pressure-sensitive adhesive layer 12 is located on the outside of the thick absorbent cotton layer 8;

[0083] The top of the medical pressure-sensitive adhesive layer 12 is connected to a symmetrically arranged release paper 13 , a peeling aid is provided on the top of the release paper 13 , a peeling layer 14 is connected to the top of the peeling aid , and a peeling label 15 is provided on the back of the peeling layer 14 .

[0084] Furthermore, the medical pressure-sensitive adhesive layer 12 is located on the outside of the thick absorbent cotton layer 8 and is made of medical-grade pressure-sensitive adhesive. It has good adhesive properties and biocompatibility, and can ensure that the medical disposable self-adhesive dressing is firmly adhered to the wound while reducing irritation and discomfort to the skin.

[0085] The release paper 13 covers the top of the medical pressure-sensitive adhesive layer 12 to protect the medical pressure-sensitive adhesive layer 12 from being contaminated or damaged during transportation and storage. The peeling aid is applied to the top of the release paper 13 to further enhance the peeling performance between the release paper 13 and the medical pressure-sensitive adhesive layer 12, ensuring that the release paper 13 can be smoothly peeled off during use. The peeling layer 14 is tightly combined with the peeling aid to provide additional peeling convenience. At the same time, the peeling layer 14 can also prevent dust or other contaminants from contacting the medical pressure-sensitive adhesive layer after peeling off the release paper 13. The peeling label 2 15 is located on the back of the peeling layer 14, which is convenient for medical staff to tear off the peeling layer 14.

[0086] Further, the manufacturing method of the medical disposable self-adhesive dressing is as follows:

[0087] S1. preparing a self-adhesive dressing base layer 1;

[0088] S2. Prepare and install a drug injection module;

[0089] S3, preparing and installing a drug storage module;

[0090] S4. Perform surface treatment.

[0091] Furthermore, in S1, the following steps are also included:

[0092] S11, uniformly coating the antibacterial coating on the surfaces of the polypropylene fiber layer, the viscose fiber layer and the cotton fiber layer, and coating the graphene antistatic coating on the surface of the antibacterial coating;

[0093] S12, stacking the polyester fiber substrate, the polypropylene fiber layer, the viscose fiber layer, and the cotton fiber layer in sequence and hot-pressing and bonding them;

[0094] In S2, the following steps are also included:

[0095] S21, injection molding the medical silicone into a medical silicone injection layer 2, pasting a medical silicone injection protective layer 3 on the bottom of the medical silicone injection layer 2, and embedding the medical silicone injection layer 2 into the self-adhesive dressing base layer 1 and fixing it;

[0096] S22, a connection cover 4 is fixedly installed at the bottom of the self-adhesive dressing base layer 1, a movable cover 5 is installed on one side of the connection cover 4, and one end of the movable cover 5 is connected to a peeling label 6;

[0097] In S3, the following steps are also included:

[0098] S31, combining the thick absorbent cotton layer 8 with the polymer fiber mesh layer 9, and applying an antibacterial coating on the surface of the polymer fiber mesh layer 9;

[0099] S32, coating the inner surface of the polyvinyl alcohol drug storage capsule 10 with a thermosensitive hydrogel, and opening evenly distributed release micropores 11 on the top, and embedding the polyvinyl alcohol drug storage capsule 10 into the thick absorbent cotton layer 8;

[0100] S33, laying an isolation layer 16 at the bottom of the thick water-absorbing cotton layer 8, and evenly opening airflow pipes 17 inside the thick water-absorbing cotton layer 8;

[0101] In S4, the following steps are also included:

[0102] S41. Apply a medical pressure-sensitive adhesive layer 12 on top of the thick absorbent cotton layer 8, and stick symmetrically arranged release papers 13 on the top of the medical pressure-sensitive adhesive layer 12. Apply a peeling aid on the top of the release paper 13 and cover the peeling layer 14. The back of the peeling layer 14 is connected to a peeling label 2 15.

[0103] Working principle: Before use, medical staff injects the drug into the polyvinyl alcohol drug storage bag 10 through the drug injection module. The drug is stably stored in the polyvinyl alcohol drug storage bag 10, and at the same time, the drug contacts the temperature-sensitive hydrogel on the inner surface. The peeling layer 14 is torn off by peeling off the label 15, and then the release paper 13 is torn off. The thick absorbent cotton layer 8 of the disposable medical self-adhesive dressing is aligned with the patient's wound and pasted. Under the influence of the temperature around the wound, the temperature-sensitive hydrogel undergoes a phase change, changing its network structure and drug diffusion rate;

[0104] The drug is released into the wound area at a controlled rate through the channels in the thermosensitive hydrogel network and the release micropores 11 on the top of the polyvinyl alcohol drug storage capsule 10. At the same time, the thick absorbent cotton layer 8 is responsible for absorbing wound exudate, keeping the wound dry, and providing a good working environment for the drug. The polymer fiber mesh layer 9 and the antibacterial coating provide additional antibacterial protection and comfort.

[0105] It will be apparent to those skilled in the art that the invention is not limited to the details of the exemplary embodiments described above and that the invention can be implemented in other specific forms without departing from the spirit or essential features of the invention. Therefore, the embodiments should be considered exemplary and non-limiting in all respects, and the scope of the invention is defined by the appended claims rather than the foregoing description, and it is intended that all variations falling within the meaning and scope of the equivalent elements of the claims be included in the invention. Any reference numeral in a claim should not be considered as limiting the claim to which it relates.

Claims

1. A disposable self-adhesive medical dressing, characterized in that: It comprises a self-adhesive dressing base layer (1), a drug injection module and a drug storage module are installed inside the self-adhesive dressing base layer (1), and the drug storage module is located above the drug injection module, the drug injection module is used to inject dressing drugs into the drug storage module, and the drug storage module is used to store dressing drugs; The drug injection module comprises a medical silicone injection layer (2) installed inside a self-adhesive dressing base layer (1), a medical silicone injection protective layer (3) is installed at the bottom of the medical silicone injection layer (2), and the medical silicone injection protective layer (3) is located at the bottom of the self-adhesive dressing base layer (1); A connecting cover (4) is installed at the bottom of the self-adhesive dressing base layer (1), and the connecting cover (4) is located on one side of the medical silicone injection protective layer (3); a movable cover (5) is installed on one side of the connecting cover (4), and the movable cover (5) is located at the bottom of the medical silicone injection protective layer (3); and a peeling label (6) is installed at one end of the movable cover (5); The top of the movable cover (5) and the bottom of the self-adhesive dressing base layer (1) are both provided with a re-adhesive coating (7), and the re-adhesive coating (7) is used for repeatedly adhering the movable cover (5); The drug storage module comprises a thick water-absorbing cotton layer (8) embedded in the self-adhesive dressing base layer (1), a polymer fiber mesh layer (9) is arranged on the top of the thick water-absorbing cotton layer (8), and an antibacterial coating is applied on the surface of the polymer fiber mesh layer (9), and the antibacterial coating is one or more of antibacterial peptides, nanosilver, chitosan and tea polyphenols; A polyvinyl alcohol drug storage bag (10) is arranged inside the thick absorbent cotton layer (8), and the polyvinyl alcohol drug storage bag (10) is located above the self-adhesive dressing base layer (1), and the top of the polyvinyl alcohol drug storage bag (10) is provided with evenly arranged release micropores (11), and the release micropores (11) are used to release the drug injected into the polyvinyl alcohol drug storage bag (10); The inner surface of the polyvinyl alcohol drug storage capsule (10) is coated with a thermosensitive hydrogel, and the model of the thermosensitive hydrogel is Pluronic F127 modified thermosensitive hydrogel; An isolation layer (16) is provided at the bottom of the thick absorbent cotton layer (8), and the isolation layer (16) is used to isolate wound exudate. Evenly arranged airflow tubes (17) are provided inside the thick absorbent cotton layer (8), and the airflow tubes (17) are used to guide wound exudate and air to flow toward the thick absorbent cotton layer (8).

2. A medical disposable self-adhesive dressing according to claim 1, characterized in that: The self-adhesive dressing base layer (1) comprises a polyester fiber base material, a polypropylene fiber layer, a viscose fiber layer, a cotton fiber layer, an antibacterial coating and a graphene antistatic coating; The top of the polyester fiber substrate is connected to a polypropylene fiber layer, the top of the polypropylene fiber layer is connected to a viscose fiber layer, the top of the viscose fiber layer is connected to a cotton fiber layer, the surfaces of the polypropylene fiber layer, the viscose fiber layer and the cotton fiber layer are all coated with an antibacterial coating, and the surface of the antibacterial coating is coated with a graphene antistatic coating.

3. A medical disposable self-adhesive dressing according to claim 2, characterized in that: The antibacterial coating is one or more of a silver ion coating, a nano silver coating and a chitosan coating.

4. A medical disposable self-adhesive dressing according to claim 1, characterized in that: A medical pressure-sensitive adhesive layer (12) is provided on the top of the self-adhesive dressing base layer (1), and the medical pressure-sensitive adhesive layer (12) is located on the outside of the thick water-absorbent cotton layer (8); The top of the medical pressure-sensitive adhesive layer (12) is connected to a symmetrically arranged release paper (13), a peeling aid is provided on the top of the release paper (13), a peeling layer (14) is connected to the top of the peeling aid, and a peeling label (15) is provided on the back of the peeling layer (14).

5. A method for manufacturing a disposable medical self-adhesive dressing, applicable to the disposable medical self-adhesive dressing according to any one of claims 1 to 4, characterized in that: The manufacturing method of the medical disposable self-adhesive dressing is as follows: S1. preparing a self-adhesive dressing base layer (1); S2. Prepare and install a drug injection module; S3, preparing and installing a drug storage module; S4, perform surface treatment; In S1, the following steps are also included: S11, uniformly coating the antibacterial coating on the surfaces of the polypropylene fiber layer, the viscose fiber layer and the cotton fiber layer, and coating the graphene antistatic coating on the surface of the antibacterial coating; S12, stacking the polyester fiber substrate, the polypropylene fiber layer, the viscose fiber layer, and the cotton fiber layer in sequence and hot-pressing and bonding them; In S2, the following steps are also included: S21, injection molding medical silicone into a medical silicone injection layer (2), pasting a medical silicone injection protective layer (3) on the bottom of the medical silicone injection layer (2), and embedding the medical silicone injection layer (2) into the self-adhesive dressing base layer (1) and fixing it; S22, a connecting cover (4) is fixedly installed at the bottom of the self-adhesive dressing base layer (1), a movable cover (5) is installed on one side of the connecting cover (4), and one end of the movable cover (5) is connected to a peel-off label (6); In S3, the following steps are also included: S31, combining the thick absorbent cotton layer (8) with the polymer fiber mesh layer (9), and applying an antibacterial coating on the surface of the polymer fiber mesh layer (9); S32, coating the inner surface of the polyvinyl alcohol drug storage capsule (10) with a thermosensitive hydrogel, and opening evenly distributed release micropores (11) on the top, and embedding the polyvinyl alcohol drug storage capsule (10) into the thick absorbent cotton layer (8); S33, laying an isolation layer (16) at the bottom of the thick absorbent cotton layer (8), and evenly opening airflow pipes (17) inside the thick absorbent cotton layer (8); In S4, the following steps are also included: S41. A medical pressure-sensitive adhesive layer (12) is coated on top of the thick absorbent cotton layer (8), and symmetrically arranged release papers (13) are pasted on top of the medical pressure-sensitive adhesive layer (12). A peeling aid is coated on the top of the release paper (13) and covers the peeling layer (14), and a peeling label (15) is connected to the back of the peeling layer (14).

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