A sampling device and sampling method for testing biotechnology pharmaceutical products

Abstract

The present invention relates to the field of medical device technology, and specifically discloses a sampling device and a sampling method for detecting biotechnology pharmaceutical products. The sampling box of the device is provided with a rotating column for rotation, the end of the rotating column passes through the sampling box, a rotating plate is fixed to the rotating column in the circumferential direction, an extrusion spring is fixed to the rotating plate, a push plate is fixed to the other end of the extrusion spring, an airbag is fixed to the other surface of the push plate, a control box is fixed to the other side of the airbag, the control box is fixed to the sampling box, a connecting pipe is provided in the control box, the connecting pipe is connected to the airbag and an upper one-way valve and a lower one-way valve are fixed to the upper and lower ends respectively, and a liquid discharge pipe and a liquid suction pipe are connected to the other ends of the upper and lower one-way valves. The method includes sampling and transfer steps. The present invention drives multiple rotating plates to rotate by a rotating column, and the airbag is squeezed and expanded by an extrusion spring, and cooperates with the upper and lower one-way valves to realize the simultaneous sampling of one or more medicines, and has the characteristics of simple structure, high sampling efficiency, easy operation and long service life.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a sampling device and a sampling method for detecting biotechnology pharmaceutical products with simple structure, high sampling efficiency, easy operation and long service life. Background Art

[0002] Biotechnology refers to the science and technology of using "organisms" to produce useful substances or improve the characteristics of organisms to reduce costs and innovate species. With the development of medicine and biotechnology, drugs and biological products produced by biotechnology are increasingly valued in modern medicine. However, unlike traditional chemical drugs, the production process of biotechnology pharmaceutical products is more complicated and inevitably leads to some quality problems. Therefore, strict quality control in the production process of biotechnology pharmaceutical products is crucial, and sampling and testing is an important means to ensure the purity, effectiveness and safety of products.

[0003] In the prior art, the sampling device for pharmaceutical products can only sample a single pharmaceutical product at a time, but in the actual working process, it is often necessary to sample multiple pharmaceutical products at the same time or extract multiple samples of the same pharmaceutical product at the same time, which not only results in the need to use multiple sampling devices for multiple samplings to meet the needs, but also has low sampling efficiency. In addition, since the multiple sampling devices have the same appearance, confusion is easy to occur in the sampling work, which adds unnecessary trouble. For this reason, in the prior art, a sampling cavity is provided at the upper part of the sampling shell and a mixing detection cavity is provided in the middle of the lower part, and then multiple sampling tubes are circumferentially installed on the outer side of the bottom of the sampling cavity, and an elastic airbag is installed at the upper end of the sampling tube in the sampling cavity, and then a pressing sampling assembly that can press and extract samples from multiple elastic airbags is installed on the sampling shell, so that the multiple elastic airbags are pressed separately by operating the pressing sampling assembly to perform separate sampling of different pharmaceutical products, or multiple sampling of the same pharmaceutical product; although the aforementioned device solves the confusion problem that is easy to be caused by separate sampling of multiple single sampling devices However, since only one sample can be extracted each time, the sampling efficiency is still low, and since the pressing sampling component directly presses the elastic airbag radially, and the elastic airbag lacks lateral constraints, the elastic airbag forms a cone when under pressure and is even easily deviated to the side, which not only leads to a lot of residue in the elastic airbag after the transfer of the agent, causing waste of the agent, but also increases the difficulty of cleaning after sampling. Moreover, the cone shape and even the side deviation make the deformation of the elastic airbag have a relatively limited impact on the space, so that the negative pressure suction generated after the rebound is also relatively limited, resulting in a small sampling amount at a time and it is difficult to control the sampling amount each time. Summary of the invention

[0004] In order to solve the deficiencies in the prior art, the present invention provides a sampling device for detecting biotech pharmaceutical products with a simple structure, high sampling efficiency, easy operation and long service life, and also provides a sampling method based on the sampling device for detecting biotech pharmaceutical products.

[0005] The sampling device of the present invention is implemented as follows: it includes a sampling box, the sampling box is a hollow structure and a rotating column is rotatably arranged inside, the end of the rotating column penetrates the top wall and / or bottom wall of the sampling box and extends outward, the rotating column in the sampling box is circumferentially spaced and fixedly arranged with at least two rotating plates, one side surface of the rotating plate is fixedly connected with an extrusion spring, the other end of the extrusion spring away from the rotating plate is fixedly connected with a push plate, the other surface of the push plate away from the extrusion spring is fixedly arranged with a flexible airbag, the other side of the airbag away from the push plate is fixedly connected with a control box, the control box is fixedly connected to the inner wall of the sampling box, a connecting pipe is vertically arranged inside the control box, the side wall of the connecting pipe is provided with a connecting port connected to the airbag, the top and bottom ends of the connecting pipe are respectively fixedly connected with an upper one-way valve and a lower one-way valve, and the other ends of the upper one-way valve and the lower one-way valve away from the connecting pipe are respectively connected with a discharge pipe and a suction pipe that penetrate the top wall and the bottom wall of the sampling box.

[0006] Furthermore, the outlet of the lower one-way valve is communicated with a connecting pipe, and the inlet of the upper one-way valve is communicated with a connecting pipe; and the connecting port of the connecting pipe is communicated with the middle or bottom of the airbag.

[0007] Furthermore, a handle is provided on the top of the sampling box, and the handle is fixedly connected to the rotating column; or a motor is provided at the top or bottom end of the sampling box, and the driving shaft of the motor is fixedly connected to the rotating column.

[0008] Furthermore, the push plate is floatingly arranged in the sampling box, and at least two extrusion springs are arranged between the push plate and the rotating plate; or one end of the push plate close to the rotating column is hinged to the rotating plate or the rotating column, and the extrusion spring is arranged in the range from the middle of the push plate and the rotating plate to close to the inner wall of the sampling box.

[0009] Furthermore, the connecting tube is a three-way joint, the top and bottom openings of the connecting tube are connected to the upper one-way valve and the lower one-way valve respectively, and the side opening of the connecting tube is connected to the airbag through a pipeline.

[0010] Furthermore, the liquid suction tube and the liquid discharge tube are both soft tubes, and the bottom end of the liquid suction tube is fixedly connected to a liquid extraction tube.

[0011] Furthermore, a bracket is fixedly provided on the top of the sampling box, and the bracket is detachably connected to the upper part of the drainage pipe.

[0012] Furthermore, at least three lifting frames are fixedly arranged at intervals at the bottom end of the sampling box, and the lifting frames include a telescopic rod. The lower sliding sleeve of the telescopic rod is provided with a sleeve with a closed bottom, and a telescopic spring is provided at the bottom end of the sleeve. The bottom end of the telescopic spring is fixedly connected to the bottom wall of the sleeve and the top end is fixedly connected to the telescopic rod.

[0013] The sampling method of the present invention is implemented as follows: based on the aforementioned sampling device for biotechnology pharmaceutical product testing, it includes the following steps:

[0014] A. Absorption: insert the pipette at the bottom of the sampling device into the corresponding medicine to be sampled, manually rotate the handle or control the motor to rotate the rotating column, and the rotating plate is driven to rotate by the rotating column to stretch the extrusion spring. The extrusion spring is forced to pull the push plate to drive the airbag to expand, thereby generating negative pressure in the airbag. Under the pressure difference between the inside and outside, the lower one-way valve automatically opens, while the upper one-way valve closes, and the medicine is sucked into the airbag through the pipette, and finally each airbag of the sampling device is respectively filled with the same medicine or different medicines;

[0015] B. Transfer: After the airbag of the sampling device has finished absorbing the medicine, manually rotate the handle or control the motor to make the rotating column rotate in the opposite direction. The rotating column drives the rotating plate to rotate to compress the extrusion spring. The extrusion spring is forced to push the push plate to squeeze the airbag, thereby increasing the pressure in the airbag. Under the pressure difference between the inside and outside, the lower one-way valve automatically closes, while the upper one-way valve opens. The medicine in the airbag passes through the upper one-way valve into the discharge pipe, and finally passes the medicine into the detection instrument through the discharge pipe, so that the medicine can be tested.

[0016] The absorption step also includes: at least three lifting racks are fixedly arranged at intervals at the bottom of the sampling box. When the pipette is needed for absorption, the sampling box is pressed downward to cause the telescopic rods in each lifting rack at the bottom of the sampling box to be stressed and squeeze the telescopic spring below. The telescopic spring is compressed and shrinks to cause the telescopic rod to slide inside the sleeve until the pipette moves downward into the medicine to complete the absorption of the medicine; after the air bag of the sampling device completes the absorption of the medicine, the sampling box is released, the telescopic spring is reset to push the telescopic rod upward along the sleeve, and the pipette is separated from the medicine and returns to a high position to complete the absorption of the medicine.

[0017] Beneficial effects of the present invention:

[0018] 1. The present invention arranges at least two rotating plates at intervals in the circumferential direction on the rotating column in the sampling box, drives the multiple rotating plates to rotate by rotating the rotating column, and squeezes and expands the airbag through the rotating plate via the extrusion spring, cooperates with the upper one-way valve and the lower one-way valve on the connecting pipe connected to the airbag, so as to absorb and discharge the medicine, realize multiple sampling of one medicine at the same time and sampling of different medicines at the same time, which not only effectively improves the sampling efficiency, but also is simple to operate, and also avoids the confusion problem that is easy to cause by sampling separately with multiple single sampling devices in the past.

[0019] 2. The rotating plate of the present invention is connected to the push plate through an extrusion spring, and is connected to the airbag through the cooperation of the push plate and the control box, so that the airbag is constrained by the push plate, the control box and the inner wall of the sampling box in the horizontal direction, and by the top and bottom walls of the sampling box in the vertical direction. Therefore, the airbag can form extreme compression when under pressure, thereby reducing the residual amount of the medicine after the transfer, and the deformation of the airbag has a greater impact on the space, and the airbag is forced to expand by directly pulling the push plate, which finally enables the airbag to form a larger expansion amount to generate sufficient negative pressure suction, which can not only absorb more medicine doses at one time to reduce the number of sampling times, but also easily and effectively control the sampling amount each time, which is conducive to the precise control of sampling.

[0020] 3. The rotating plate of the present invention is connected to the push plate through an extrusion spring, and is connected to the airbag through the cooperation of the push plate and the control box. Since the deformation of the extrusion spring has nonlinear characteristics, it can effectively slow down the acceleration acting on the airbag when the rotating plate is started to squeeze and expand, thereby reducing or even avoiding the damage to the airbag caused by rapid pulling and mutual friction, and effectively extending the service life of the sampling device.

[0021] In summary, the present invention has the characteristics of simple structure, high sampling efficiency, easy operation and long service life. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 It is a schematic diagram of the structure of the present invention;

[0023] Figure 2 It is a schematic diagram of the interior structure of the sampling box and its connecting pipelines of the present invention;

[0024] Figure 3 for Figure 2 A top view of

[0025] Figure 4 for Figure 2 A partial cross-sectional view of

[0026] Figure 5 for Figure 4 A front view of

[0027] Figure 6 It is a schematic diagram of the lifting frame structure of the present invention;

[0028] In the figure: 1- bracket, 2- sampling box, 3- lifting frame, 31- telescopic rod, 32- sleeve, 33- telescopic spring, 4- suction tube, 5- discharge tube, 6- rotating column, 7- rotating plate, 8- pushing plate, 9- air bag, 10- extrusion spring, 11- control box, 12- lower one-way valve, 13- connecting pipe, 14- upper one-way valve, 15- liquid extraction capillary. DETAILED DESCRIPTION

[0029] In order to make the purpose, technical solution and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0030] It should be noted that the drawings are in very simplified form and in non-precise proportions, and are only used to conveniently and clearly assist in explaining the purpose of the embodiments of the present invention. In the following description, in order to avoid confusion due to unnecessary details, well-known functions and structures are no longer described in detail.

[0031] like Figures 1 to 6 As shown, the sampling device for detecting biotech pharmaceutical products of the present invention comprises a sampling box 2, wherein the sampling box 2 is a hollow structure and a rotating column 6 is rotatably arranged inside, and the end of the rotating column 6 penetrates the top wall and / or the bottom wall of the sampling box 2 and extends outward, and the rotating column 6 in the sampling box 2 is fixedly provided with at least two rotating plates 7 at intervals in the circumferential direction, and a compression spring 10 is fixedly connected to a surface of one side of the rotating plate 7, and a push plate 8 is fixedly connected to the other end of the compression spring 10 away from the rotating plate 7, and a push plate 8 is fixedly provided on the other surface of the push plate 8 away from the compression spring 10 A flexible airbag 9, the other side of the airbag 9 away from the push plate 8 is fixedly connected to a control box 11, the control box 11 is fixedly connected to the inner wall of the sampling box 2, a connecting pipe 13 is vertically arranged inside the control box 11, the side wall of the connecting pipe 13 is provided with a connecting port connected to the airbag 9, the top and bottom ends of the connecting pipe 13 are respectively fixedly connected with an upper one-way valve 14 and a lower one-way valve 12, the other ends of the upper one-way valve 14 and the lower one-way valve 12 away from the connecting pipe 13 are respectively connected with a discharge pipe 5 and a suction pipe 4 that penetrate the top wall and the bottom wall of the sampling box 2.

[0032] The outlet of the lower one-way valve 12 is communicated with the connecting pipe 13 , and the inlet of the upper one-way valve 14 is communicated with the connecting pipe 13 ; the connecting port of the connecting pipe 13 is communicated with the middle or bottom of the airbag 9 .

[0033] A handle is provided on the top of the sampling box 2 , and the handle is fixedly connected to the rotating column 6 ; or a motor is provided at the top or bottom end of the sampling box 2 , and the driving shaft of the motor is fixedly connected to the rotating column 6 .

[0034] The push plate 8 is floatingly arranged in the sampling box 2, and at least two extrusion springs 10 are arranged between the push plate 8 and the rotating plate 7; or one end of the push plate 8 close to the rotating column 6 is hinged to the rotating plate 7 or the rotating column 6, and the extrusion spring 10 is arranged in the range from the middle of the push plate 8 and the rotating plate 7 to close to the inner wall of the sampling box 2.

[0035] The connecting tube 13 is a three-way joint, and the top and bottom openings of the connecting tube 13 are connected to the upper one-way valve 14 and the lower one-way valve 12 respectively, and the side opening of the connecting tube 13 is connected to the airbag 9 through a pipeline.

[0036] The liquid suction tube 4 and the liquid discharge tube 5 are both soft tubes, and the bottom end of the liquid suction tube 4 is fixedly connected to a liquid extraction tube 15 .

[0037] A bracket 1 is fixedly provided on the top of the sampling box 2 , and the bracket 1 is detachably connected to the upper part of the drainage pipe 5 .

[0038] At least three lifting frames 3 are fixedly arranged at intervals at the bottom end of the sampling box 2, and the lifting frames 3 include a telescopic rod 31. The lower sliding sleeve of the telescopic rod 31 is provided with a sleeve 32 with a closed bottom. A telescopic spring 33 is provided at the bottom end of the sleeve 32. The bottom end of the telescopic spring 33 is fixedly connected to the bottom wall of the sleeve 32 and the top end is fixedly connected to the telescopic rod 31.

[0039] like Figures 1 to 6 As shown, the sampling method for biotechnology pharmaceutical product detection of the present invention is based on the aforementioned sampling device for biotechnology pharmaceutical product detection, and comprises the following steps:

[0040] A. Absorption: insert the pipette 4 at the lower part of the sampling device into the corresponding medicine to be sampled, manually rotate the handle or control the motor to rotate the rotating column 6, and the rotating plate 7 is driven to rotate by the rotating column 6 to stretch the extrusion spring 10. The extrusion spring 10 is forced to pull the push plate 8 to drive the airbag 9 to expand, thereby generating negative pressure in the airbag 9. Under the pressure difference between the inside and the outside, the lower one-way valve 12 automatically opens, and the upper one-way valve 14 closes, and the medicine is sucked into the airbag 9 through the pipette 4, and finally each airbag 9 of the sampling device is respectively filled with the same medicine or different medicines;

[0041] B. Transfer: After the airbag 9 of the sampling device completes absorbing the medicine, manually rotate the handle or control the motor to make the rotating column 6 rotate in the opposite direction. The rotating column 6 drives the rotating plate 7 to rotate to compress the extrusion spring 10. The extrusion spring 10 is forced to push the push plate 8 to squeeze the airbag 9. As a result, the pressure in the airbag 9 increases. Under the pressure difference between the inside and the outside, the lower one-way valve 12 automatically closes, while the upper one-way valve 14 opens. The medicine in the airbag 9 enters the discharge pipe 5 through the upper one-way valve 14, and finally passes the medicine into the detection instrument through the discharge pipe 5, so that the medicine can be detected.

[0042] The absorption step also includes: at least three lifting frames 3 are fixedly arranged at intervals at the bottom end of the sampling box 2. When the pipette 4 is needed for absorption, the sampling box 2 is pressed downward to make the telescopic rods 31 in each lifting frame 3 at the bottom of the sampling box 2 bear force and squeeze the telescopic spring 33 below. The telescopic spring 33 is compressed and shrinks to make the telescopic rod 31 slide inside the sleeve 32 until the pipette 4 moves downward into the medicine to complete the absorption of the medicine; after the air bag 9 of the sampling device completes the absorption of the medicine, the sampling box 2 is released, the telescopic spring 33 is reset to push the telescopic rod 31 upward along the sleeve 32, and the pipette 4 is separated from the medicine and returns to a high position to complete the absorption of the medicine.

[0043] Example 1

[0044] like Figures 1 to 5 As shown, the sampling process is as follows:

[0045] S100: insert the pipette 4 at the lower part of the sampling device into the medicine to be sampled, manually rotate the handle or control the motor to rotate the rotating column 6, and drive the rotating plate 7 to rotate through the rotating column 6 to stretch the extrusion spring 10. The extrusion spring 10 is forced to pull the push plate 8 to drive the airbag 9 to expand, thereby generating negative pressure in the airbag 9. Under the pressure difference between the inside and the outside, the lower one-way valve 12 automatically opens, and the upper one-way valve 14 closes, and the medicine is sucked into the airbag 9 through the pipette 4, and finally each airbag 9 of the sampling device is respectively filled with the same medicine or different medicines;

[0046] S200: After the airbag 9 of the sampling device completes absorbing the medicine, manually rotate the handle or control the motor to make the rotating column 6 rotate in the opposite direction, and the rotating plate 7 is driven by the rotating column 6 to rotate to compress the extrusion spring 10. The extrusion spring 10 is forced to push the push plate 8 to squeeze the airbag 9, thereby increasing the pressure inside the airbag 9. Under the pressure difference between the inside and outside, the lower one-way valve 12 is automatically closed, and the upper one-way valve 14 is opened. The medicine in the airbag 9 enters the discharge pipe 5 through the upper one-way valve 14, and finally passes the medicine into the detection instrument through the discharge pipe 5, so that the medicine can be detected.

[0047] Example 2

[0048] like Figures 1 to 6 As shown, the sampling process is as follows:

[0049] S100: First, move the sampling device to the top of the medicine to be sampled, and then press the sampling box 2 downward, so that the telescopic rod 31 in each lifting frame 3 at the bottom of the sampling box 2 is stressed and squeezes the telescopic spring 33 below. The telescopic spring 33 is compressed and shrinks, and the telescopic rod 31 slides inside the sleeve 32 until the pipette 4 moves downward into the medicine; then manually rotate the handle or control the motor to rotate the rotating column 6, and the rotating plate 7 is driven by the rotating column 6 to rotate to stretch the squeezing spring 10. The extrusion spring 10 is forced to pull the push plate 8 to drive the airbag 9 to expand, thereby generating negative pressure in the airbag 9. Under the pressure difference between the inside and the outside, the lower one-way valve 12 automatically opens, while the upper one-way valve 14 closes, and the medicine is sucked into the airbag 9 through the pipette 4, and finally each airbag 9 of the sampling device is filled with the same medicine or different medicines; then the sampling box 2 is released, the telescopic spring 33 is reset to push the telescopic rod 31 upward along the sleeve 32, and the pipette 4 is separated from the medicine and returns to a high position, completing the absorption of the medicine.

[0050] S200: The content is the same as the same step in Example 1.

[0051] The above is only a preferred specific embodiment of the present invention, but the protection scope of the present invention is not limited thereto. Any changes or substitutions that can be easily thought of by any technician familiar with the technical field within the technical scope disclosed by the present invention should be included in the protection scope of the present invention. Therefore, the protection scope of the present invention should be based on the protection scope of the claims.

Claims

1. A sampling device for testing biotechnology pharmaceutical products, characterized in that: The sampling box (2) comprises a sampling box (2), wherein the sampling box (2) is a hollow structure and a rotating column (6) is rotatably arranged inside the sampling box (2), the end of the rotating column (6) penetrates the top wall and / or the bottom wall of the sampling box (2) and extends outward, the rotating column (6) in the sampling box (2) is fixedly provided with at least two rotating plates (7) at intervals in the circumferential direction, a surface of one side of the rotating plate (7) is fixedly connected to a pressing spring (10), the other end of the pressing spring (10) away from the rotating plate (7) is fixedly connected to a push plate (8), the other surface of the push plate (8) away from the pressing spring (10) is fixedly provided with a flexible air bag (9), the air bag (9 ) is fixedly connected to a control box (11) on the other side away from the push plate (8), the control box (11) is fixedly connected to the inner wall of the sampling box (2), a connecting pipe (13) is vertically arranged inside the control box (11), the side wall of the connecting pipe (13) is provided with a connecting port connected to the air bag (9), the top and bottom ends of the connecting pipe (13) are respectively fixedly connected to an upper one-way valve (14) and a lower one-way valve (12), and the other ends of the upper one-way valve (14) and the lower one-way valve (12) away from the connecting pipe (13) are respectively connected to a discharge pipe (5) and a suction pipe (4) that penetrate the top wall and the bottom wall of the sampling box (2); The outlet of the lower one-way valve (12) is in communication with the connecting pipe (13), and the inlet of the upper one-way valve (14) is in communication with the connecting pipe (13); the connecting port of the connecting pipe (13) is in communication with the middle or bottom of the airbag (9); A handle is provided above the sampling box (2), and the handle is fixedly connected to the rotating column (6); or a motor is provided at the top or bottom of the sampling box (2), and the drive shaft of the motor is fixedly connected to the rotating column (6); The push plate (8) is floatingly arranged in the sampling box (2), and at least two extrusion springs (10) are arranged between the push plate (8) and the rotating plate (7); or one end of the push plate (8) close to the rotating column (6) is hinged to the rotating plate (7) or the rotating column (6), and the extrusion spring (10) is arranged in the range from the middle of the push plate (8) and the rotating plate (7) to the inner wall of the sampling box (2).

2. The sampling device for biotechnology pharmaceutical product testing according to claim 1, characterized in that: The connecting tube (13) is a three-way joint. The top and bottom openings of the connecting tube (13) are respectively connected to the upper one-way valve (14) and the lower one-way valve (12). The side opening of the connecting tube (13) is connected to the airbag (9) through a pipeline.

3. The sampling device for biotechnology pharmaceutical product testing according to claim 1, characterized in that: The liquid suction tube (4) and the liquid discharge tube (5) are both soft tubes, and the bottom end of the liquid suction tube (4) is fixedly connected to a liquid extraction capillary tube (15).

4. The sampling device for biotechnology pharmaceutical product testing according to claim 1, characterized in that: A bracket (1) is fixedly provided on the top of the sampling box (2), and the bracket (1) is detachably connected to the upper part of the drainage pipe (5).

5. The sampling device for biotechnology pharmaceutical product testing according to any one of claims 1 to 4, characterized in that: At least three lifting frames (3) are fixedly arranged at intervals at the bottom end of the sampling box (2), and the lifting frame (3) includes a telescopic rod (31). The lower sliding sleeve of the telescopic rod (31) is provided with a sleeve (32) with a closed bottom. The bottom end of the sleeve (32) is provided with a telescopic spring (33), and the bottom end of the telescopic spring (33) is fixedly connected to the bottom wall of the sleeve (32) and the top end is fixedly connected to the telescopic rod (31).

6. A sampling method for testing biotechnology pharmaceutical products, characterized in that: The sampling device for detecting biotechnology pharmaceutical products according to any one of claims 1 to 5 comprises the following steps: A. Absorption: insert the pipette (4) at the lower part of the sampling device into the corresponding medicine to be sampled, manually rotate the handle or control the motor to rotate the rotating column (6), and drive the rotating plate (7) to rotate through the rotating column (6) to stretch the extrusion spring (10). The extrusion spring (10) is forced to pull the push plate (8) to drive the airbag (9) to expand, thereby generating negative pressure in the airbag (9). Under the pressure difference between the inside and outside, the lower one-way valve (12) automatically opens, while the upper one-way valve (14) closes, and the medicine is sucked into the airbag (9) through the pipette (4), and finally each airbag (9) of the sampling device is respectively filled with the same medicine or different medicines; B. Transfer: After the airbag (9) of the sampling device has finished absorbing the medicine, the handle is manually rotated or the motor is controlled to rotate the rotating column (6) in the opposite direction. The rotating column (6) drives the rotating plate (7) to rotate to compress the extrusion spring (10). The extrusion spring (10) is forced to push the push plate (8) to squeeze the airbag (9). As a result, the pressure in the airbag (9) increases. Under the pressure difference between the inside and outside, the lower one-way valve (12) is automatically closed, while the upper one-way valve (14) is opened. The medicine in the airbag (9) passes through the upper one-way valve (14) and enters the discharge pipe (5). Finally, the medicine is passed through the discharge pipe (5) into the detection instrument, and the medicine can be detected.

7. The sampling method for biotechnology pharmaceutical product testing according to claim 6, characterized in that: The absorption step also includes: at least three lifting racks (3) are fixedly arranged at intervals at the bottom of the sampling box (2); when the pipette (4) needs to absorb, the sampling box (2) is pressed downward, so that the telescopic rods (31) in each lifting rack (3) at the bottom of the sampling box (2) are stressed and squeeze the telescopic spring (33) below, and the telescopic spring (33) is compressed and shrinks to make the telescopic rod (31) slide inside the sleeve (32) until the pipette (4) moves downward into the medicine to complete the absorption of the medicine; after the air bag (9) of the sampling device completes the absorption of the medicine, the sampling box (2) is released, the telescopic spring (33) is reset to push the telescopic rod (31) upward along the sleeve (32), and the pipette (4) is separated from the medicine and returns to a high position, completing the absorption of the medicine.

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