Oral spray for relieving tongue sores

Abstract

The invention provides oral spray liquid for relieving tongue sores. The oral spray liquid is prepared from the following components in percentage by weight: 4 to 8 percent of herba orostachyos extract, 2 to 6 percent of fresh ginger extract and 88 to 92 percent of preserving fluid. The oral spray liquid disclosed by the invention has the effect of relieving tongue sores. The oral spray liquid prepared by uniformly mixing the herba orostachyos extract and the fresh ginger extract according to a ratio and adding a preserving fluid has a remarkable effect on relieving tongue sores, and has a good application prospect.

Description

Technical Field

[0001] The invention belongs to the technical field of development of oral care products, and in particular relates to an oral spray liquid for relieving tongue sores. Background Art

[0002] Oral health is an important part of human health and has been widely valued by the public. The oral health status has also become a mirror reflecting the quality of life and health of modern people. Tongue sores are a common oral disease with the characteristics of recurrence, periodicity and self-limitation. After the occurrence of tongue sores, if some prevention is not timely, it will also cause local burning pain, which will affect speaking and eating, and easily cause symptoms such as pharyngitis, bad breath, and swollen lymph nodes. At present, most clinical drugs for tongue sores are Western medicines, which are generally single in composition, and the main mode of administration is application and application. There are many disadvantages such as inconvenience in use, slow onset and obvious toxic and side effects. Therefore, the development of a tongue sore relief spray that is easy to use, has a rapid and significant onset and has no toxic and side effects has important practical significance for oral health and even systemic health.

[0003] Both Osmanthus and ginger are both medicinal and edible plants. They have a long history of medicinal and edible use in my country and are two plants of great value. Osmanthus is a dicotyledonous perennial herb whose underground tubers are often eaten as fruits. It is a food that can be used as both medicine and food. However, in recent years, there have been relatively few applied studies on these two plants, which is not conducive to their high-value development, application and promotion. Therefore, the development of an oral spray liquid with Osmanthus extract and ginger extract as active ingredients can effectively expand the high-value development direction of Osmanthus and ginger, and has potential economic, social and ecological value. Summary of the invention

[0004] The invention discloses an oral spray liquid for relieving tongue sores, and aims to overcome the problems existing in existing tongue sore care products, develop a tongue sore care product with orthoclase extract and ginger extract as effective ingredients, and effectively relieve tongue sores and broaden the application direction of orthoclase extract and ginger extract.

[0005] The present invention provides an oral spray liquid for relieving tongue sores, the components and mass percentages of which are: 4% to 8% of Orthospermum officinale extract, 2% to 6% of ginger extract, and 88% to 92% of preservative solution; The extract of Ornithogalum japonicum is a mixture of products obtained by water extraction and ethanol extraction of fresh Ornithogalum japonicum plants, and then concentrated under reduced pressure to obtain a viscous liquid; The ginger extract is a mixture of fresh ginger juice and ethanol extract of the remaining peel residue after squeezing the juice, which is a liquid substance obtained by decompression concentration; The components and weight ratio of the preservation solution are: 26% anhydrous ethanol, 5.5% antioxidant, 6% sweetener, and 62.5% sterile water; The antioxidant is one of tea polyphenols or vitamin C or a combination of the two; The sweetener is menthol or xylitol or a combination of the two.

[0006] The benefit of the present invention is that the present invention provides an oral spray liquid with the effect of relieving tongue sores, and its active ingredients are wormwood extract and ginger extract. The oral spray liquid has a significant relieving effect on tongue sores, and is an oral care product with simple compatibility, simple preparation, green and safe, and no toxic side effects, and has good application and economic benefit prospects. It was verified through experiments that the wormwood extract, ginger extract, and preservation solution described in the present invention are not simply mixed and superimposed, but are a specific combination based on the premise of significantly superior effects produced by a single substance. That is, the oral spray liquid of the present invention does not rely on the efficacy of a single substance or the simple superposition of the efficacy of a single substance, but is a specific substance in a specific combination that produces an unexpected technical effect that is significantly superior to the prior art. Therefore, it has obvious novelty, creativity, and practicality. DETAILED DESCRIPTION

[0007] The principles and features of the present invention are described below in conjunction with examples. The examples are only used to explain the present invention and are not used to limit the scope of the present invention.

[0008] Example 1. An oral spray for relieving tongue sores, the components and mass percentages of which are: 4% of Orchis japonicus extract, 6% of ginger extract, and 90% of preservative solution; The extract of Ornithogalum japonicum is a mixture of products obtained by water extraction and ethanol extraction of fresh Ornithogalum japonicum plants, and then concentrated under reduced pressure to obtain a viscous liquid; The ginger extract is a mixture of fresh ginger juice and ethanol extract of the remaining peel residue after squeezing the juice, which is a liquid substance obtained by decompression concentration; The components and weight ratio of the preservation solution are: 26% anhydrous ethanol, 5.5% antioxidant, 6% sweetener, and 62.5% sterile water; The antioxidant is tea polyphenols; The sweetener is xylitol.

[0009] Example 2. An oral spray for relieving tongue sores, the components and mass percentages of which are: 8% of Orchis japonicus extract, 4% of ginger extract, and 88% of preservative solution; The extract of Ornithogalum japonicum is a mixture of products obtained by water extraction and ethanol extraction of fresh Ornithogalum japonicum plants, and then concentrated under reduced pressure to obtain a viscous liquid; The ginger extract is a mixture of fresh ginger juice and ethanol extract of the remaining peel residue after squeezing the juice, which is a liquid substance obtained by decompression concentration; The components and weight ratio of the preservation solution are: 26% anhydrous ethanol, 5.5% antioxidant, 6% sweetener, and 62.5% sterile water; The antioxidant is vitamin C; The sweetener is menthol.

[0010] Example 3. An oral spray for relieving tongue sores, the components and mass percentages of which are: 6% of Orchis japonicus extract, 2% of ginger extract, and 92% of preservative solution; The extract of Ornithogalum japonicum is a mixture of products obtained by water extraction and ethanol extraction of fresh Ornithogalum japonicum plants, and then concentrated under reduced pressure to obtain a viscous liquid; The ginger extract is a mixture of fresh ginger juice and ethanol extract of the remaining peel residue after squeezing the juice, which is a liquid substance obtained by decompression concentration; The components and weight ratio of the preservation solution are: 26% anhydrous ethanol, 5.5% antioxidant, 6% sweetener, and 62.5% sterile water; The antioxidant is a mixture of tea polyphenols and vitamin C in equal amounts; The sweetener is a mixture of menthol and xylitol in equal amounts.

[0011] Comparative Example 1. Referring to Example 1, the Orthosthenes extract was replaced with ginger extract, and the remaining technical features were the same as those in Example 1, that is, a comparative example without Orthosthenes extract was prepared.

[0012] Comparative Example 2. Referring to Example 2, the ginger extract was replaced with the Orthospermum officinale extract. The remaining technical features were the same as those of Example 2, that is, a comparative example without ginger extract was prepared.

[0013] Comparative Example 3. Referring to Example 3, the preservation solution was replaced with sterile water, and the remaining technical features were the same as those of Example 3, that is, a comparative example without preservation solution was prepared.

[0014] Experiment. 70 patients (age range 20-55 years old) with tongue sores from February 2023 to July 2024 were selected as test subjects for a tongue sore spray relief test. Set up 3 groups of embodiments (Example 1, Example 2, Example 3), 3 groups of comparative examples (Comparative Example 1, Comparative Example 2, Comparative Example 3), and 1 control group, for a total of 7 groups. 70 patients were randomly assigned to 7 treatment groups, 10 cases in each group. The control group patients used physiological saline as a reagent, and the remaining groups used oral spray liquids prepared in their respective corresponding cases as reagents. The treatment cycle is 10 days. During the treatment cycle, the affected area is sprayed once in the morning, noon, and evening every day. After spraying, fasting and water deprivation for 30 minutes, and the interval between two sprayings is more than 4 hours. The volunteer patients were interviewed by video for 10 consecutive days to observe the healing of their tongue sores. The wound healing area reached 90% and the pain disappeared, which was recorded as a cured case. The cure rate was calculated by the number of cured cases / total number of cases in the group × 100%. The results are shown in Table 1:

[0015] As shown in Table 1, the recovery period of patients in Examples 1-3 and Comparative Examples 1-3 were significantly ( P＜ 0.05 ) shortened, proving that each group of the embodiment and each group of the comparative example had a certain effect on relieving tongue sores. Compared with the control group and the comparative example 1-3 groups, the embodiment 1-3 groups had extremely significant ( P＜0.01 ) is shortened, proving that the Orthoclase extract, ginger extract, and preservation solution in the oral spray of the present invention all play an important role in alleviating tongue sores, and none of them is indispensable, and they cannot replace each other. This experiment proves that the Orthoclase extract, ginger extract, and preservation solution described in the present invention are not simply mixed and superimposed, but are a specific combination based on the premise of significantly better effects than those produced by a single substance. That is, the oral spray of the present invention does not rely on the efficacy of a single substance or the simple superposition of the efficacy of a single substance, but is a specific substance that produces an unexpected technical effect that is significantly better than the prior art under a specific combination.

[0016] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. An oral spray for relieving tongue sores, characterized in that: The preparation method is obtained by uniformly mixing the following components in mass percentage: 4% to 8% of Orthospermum officinale extract, 2% to 6% of ginger extract, and 88% to 92% of preservation solution.

2. An oral spray for relieving tongue sores according to claim 1, characterized in that: The composition of the preservation solution is: Anhydrous ethanol, antioxidant, sweetener, sterile water.

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