Traditional Chinese medicine composition and decoction for treating alimentary canal tissue erosion and preparation method of traditional Chinese medicine composition and decoction

Abstract

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition and decoction for treating alimentary canal tissue erosion and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following components in parts by mass: 15-25 parts of Chinese yam, 15-25 parts of rhizoma smilacis glabrae, 15-25 parts of radix salviae miltiorrhizae, 10-20 parts of raw coix seeds, 10-20 parts of fingered citron, 10-20 parts of pericarpium citri reticulatae, 10-20 parts of fructus trichosanthis, 5-15 parts of radix polygonati officinalis, 5-15 parts of cortex moutan, 5-15 parts of radix morindae officinalis, 5-15 parts of herba cistanche, 5-15 parts of rhizoma atractylodis macrocephalae, 5-15 parts of fresh ginger, 5-15 parts of radix bupleuri and 5-15 parts of radix codonopsis. The traditional Chinese medicine composition disclosed by the invention has the effects of tonifying spleen, regulating qi, tonifying kidney and regulating liver. The composition is safe, non-toxic and sustainable to take, and although the medication time is long, the body function can be comprehensively improved, the digestive tract tissue can be completely repaired, and further damage and malignant change of the tissue can be relieved.

Description

Technical Field

[0001] This invention relates to the field of traditional Chinese medicine technology, and in particular to a traditional Chinese medicine composition, decoction, and preparation method for treating digestive tract tissue erosion. Background Technology

[0002] Endoscopy is necessary for digestive issues. Currently, the rate of endoscopy has increased significantly in areas with a high incidence of esophageal and gastric cancer, among individuals with a family history of the disease, and those with unhealthy dietary habits and lifestyles. For patients with precancerous lesions or esophageal cancer detected through screening, treatment and follow-up according to clinical guidelines are recommended. For those with negative screening results, health education should be provided regarding their high-risk factors, and they should be reminded to undergo regular screenings as required.

[0003] A single endoscopic examination by a professional institution can completely examine the esophagus, stomach, and duodenum. For high-risk individuals who test negative in screening but have chronic diseases detected in their examinations, regular screening is insufficient to address the problem; seeking a safe and effective method for improvement is more necessary.

[0004] Although the appearance and function of different segments of the digestive tract are not entirely the same, they share common structural characteristics, all consisting of a mucosa, submucosa, muscularis propria, and adventitia. The muscularis propria of the stomach is a continuation of the esophageal muscularis propria and transitions into the duodenum. The esophagus, stomach, and duodenum influence each other due to the availability of gastric juice and bile. Therefore, improving the condition of the esophagus, stomach, and duodenum requires considering the needs of each other.

[0005] The acid-base environment of the esophagus, stomach, and duodenum contains unique gastric and intestinal fluids. While conventional Western medicine attempts to regulate this acid-base balance, it's difficult to simultaneously address all three. Furthermore, significant individual differences make combination therapy challenging, potentially harmful, and often lacking sustained effectiveness with minimal improvement. Therefore, developing a product that can simultaneously address all three without causing harm is urgently needed. Summary of the Invention

[0006] The purpose of this invention is to provide a safe, non-toxic traditional Chinese medicine composition that can completely repair digestive tract tissues and slow down further tissue damage and malignant transformation. In particular, it relates to a traditional Chinese medicine composition, decoction and preparation method for treating digestive tract tissue erosion.

[0007] To achieve the above-mentioned objectives, the present invention provides the following technical solution:

[0008] This invention provides a traditional Chinese medicine composition for treating erosion of the digestive tract tissues, comprising the following components in parts by weight:

[0009] 15 - 25 parts of Chinese yam, 15 - 25 parts of glabrous greenbrier, 15 - 25 parts of salvia miltiorrhiza, 10 - 20 parts of coix seed, 10 - 20 parts of fingered citron, 10 - 20 parts of dried tangerine peel, 10 - 20 parts of trichosanthes kirilowii, 5 - 15 parts of polygonatum odoratum, 5 - 15 parts of moutan bark, 5 - 15 parts of morinda officinalis, 5 - 15 parts of cistanche deserticola, 5 - 15 parts of bighead atractylodes rhizome, 5 - 15 parts of ginger, 5 - 15 parts of bupleurum chinense, 5 - 15 parts of codonopsis pilosula.

[0010] Preferably, it comprises the following components in parts by mass:

[0011] 17 - 23 parts of Chinese yam, 17 - 23 parts of glabrous greenbrier, 17 - 23 parts of salvia miltiorrhiza, 12 - 18 parts of coix seed, 12 - 18 parts of fingered citron, 12 - 18 parts of dried tangerine peel, 12 - 18 parts of trichosanthes kirilowii, 7 - 13 parts of polygonatum odoratum, 7 - 13 parts of moutan bark, 7 - 13 parts of morinda officinalis, 7 - 13 parts of cistanche deserticola, 7 - 13 parts of bighead atractylodes rhizome, 7 - 13 parts of ginger, 7 - 13 parts of bupleurum chinense, 7 - 13 parts of codonopsis pilosula.

[0012] Preferably, it comprises the following components in parts by mass:

[0013] 20 parts of Chinese yam, 20 parts of glabrous greenbrier, 20 parts of salvia miltiorrhiza, 15 parts of coix seed, 15 parts of fingered citron, 15 parts of dried tangerine peel, 15 parts of trichosanthes kirilowii, 10 parts of polygonatum odoratum, 10 parts of moutan bark, 10 parts of morinda officinalis, 10 parts of cistanche deserticola, 10 parts of bighead atractylodes rhizome, 10 parts of ginger, 10 parts of bupleurum chinense, 10 parts of codonopsis pilosula.

[0014] Preferably, the fingered citron is Guang fingered citron;

[0015] The dried tangerine peel is Guang dried tangerine peel;

[0016] The trichosanthes kirilowii is whole trichosanthes kirilowii.

[0017] The present invention also provides the application of the described traditional Chinese medicine composition in the preparation of a medicament for treating digestive tract tissue erosion.

[0018] The present invention also provides a decoction for treating digestive tract tissue erosion, which is prepared from the described traditional Chinese medicine composition.

[0019] The present invention also provides a preparation method of a decoction for treating digestive tract tissue erosion, comprising the following steps:

[0020] (1) Weigh each component according to the described parts by mass to obtain a traditional Chinese medicine composition;

[0021] (2) Mix the described traditional Chinese medicine composition with water, soak for 25 - 35 min, then decoct for 20 - 30 min, and filter to obtain residue and the first filtrate;

[0022] (3) Mix the residue obtained in step (2) with water, decoct for 20 - 30 min, filter, and collect the filtrate to obtain the second filtrate.

[0023] (4) Combine the first and second filtrates to obtain the decoction.

[0024] Preferably, the mass ratio of the traditional Chinese medicine composition to water in step (2) is 1:2 to 4.

[0025] Preferably, the mass ratio of the filter residue to water in step (3) is 1:1 to 3.

[0026] Preferably, the filtration in steps (2) to (3) consists of 3 to 4 layers of gauze filtration.

[0027] This invention provides a traditional Chinese medicine composition, decoction, and preparation method for treating digestive tract tissue erosion. The traditional Chinese medicine composition of this invention comprises the following components in parts by weight: 15-25 parts of Dioscorea opposita, 15-25 parts of Smilax glabra, 15-25 parts of Salvia miltiorrhiza, 10-20 parts of raw Coix lacryma-jobi, 10-20 parts of Citrus medica var. sarcodactylis, 10-20 parts of Citrus reticulata peel, 10-20 parts of Trichosanthes kirilowii, 5-15 parts of Polygonatum odoratum, 5-15 parts of Paeonia suffruticosa root bark, 5-15 parts of Morinda officinalis, 5-15 parts of Cistanche deserticola, 5-15 parts of Atractylodes macrocephala, 5-15 parts of fresh ginger, 5-15 parts of Bupleurum chinense, and 5-15 parts of Codonopsis pilosula. The traditional Chinese medicine composition of this invention has the effects of strengthening the spleen, regulating qi, tonifying the kidneys, and regulating the liver. The formula is safe, non-toxic, and can be taken continuously. Although the treatment period is relatively long, it can comprehensively improve bodily functions, more completely repair digestive tract tissues, and slow down further tissue damage and malignant transformation. Attached Figure Description

[0028] Figure 1 The results of Ding*'s physical examination before treatment;

[0029] Figure 2 The results of gastroscopy one year after treatment for Ding*;

[0030] Figure 3 The results of Ding*rong's gastroscopy before treatment;

[0031] Figure 4 The results of the gastroscopy after Ding*rong's treatment;

[0032] Figure 5 The results of Duan*ping's gastroscopy before treatment;

[0033] Figure 6 The results of the gastroscopy after Duan*ping's treatment;

[0034] Figure 7 The results of gastroscopy before Gu*ying's treatment;

[0035] Figure 8 The results of gastroscopy after Gu*ying's treatment;

[0036] Figure 9 The results of Zhong*hua's gastroscopy before treatment;

[0037] Figure 10 The results of gastroscopy after Zhong*hua's treatment;

[0038] Figure 11 The results of Zou*jin's gastroscopy before treatment;

[0039] Figure 12 The results of the gastroscopy after Zou*jin's treatment. Detailed Implementation

[0040] This invention provides a traditional Chinese medicine composition for treating erosion of the digestive tract tissues, comprising the following components in parts by weight:

[0041] The amount of yam is 15-25 parts, preferably 17-23 parts, and more preferably 20 parts;

[0042] Smilax glabra (Tufuling) 15-25 parts, preferably 17-23 parts, and even more preferably 20 parts;

[0043] 15-25 parts of Salvia miltiorrhiza, preferably 17-23 parts, and even more preferably 20 parts;

[0044] 10-20 parts of raw Job's tears, preferably 12-18 parts, and even more preferably 15 parts;

[0045] 10-20 parts of Buddha's Hand, preferably 12-18 parts, and more preferably 15 parts;

[0046] 10-20 parts of dried tangerine peel, preferably 12-18 parts, and even more preferably 15 parts;

[0047] Trichosanthes kirilowii 10-20 parts, preferably 12-18 parts, more preferably 15 parts;

[0048] 5 to 15 parts of Polygonatum odoratum, preferably 7 to 13 parts, and more preferably 10 parts;

[0049] 5 to 15 parts of peony bark, preferably 7 to 13 parts, and more preferably 10 parts;

[0050] Morinda officinalis 5-15 parts, preferably 7-13 parts, and more preferably 10 parts;

[0051] 5-15 parts of Cistanche deserticola, preferably 7-13 parts, and even more preferably 10 parts;

[0052] 5-15 parts of Atractylodes macrocephala, preferably 7-13 parts, and more preferably 10 parts;

[0053] 5 to 15 parts of ginger, preferably 7 to 13 parts, and more preferably 10 parts;

[0054] Bupleurum chinense: 5-15 parts, preferably 7-13 parts, and more preferably 10 parts;

[0055] The dosage of Codonopsis pilosula is 5-15 parts, preferably 7-13 parts, and even more preferably 10 parts.

[0056] In this invention, the Buddha's Hand is a Guangfo Shou, which is a Buddha's Hand produced in Guangdong Province;

[0057] The tangerine peel mentioned is Guangchenpi, which is tangerine peel produced in Guangdong Province;

[0058] The Trichosanthes kirilowii mentioned refers to the whole Trichosanthes kirilowii fruit.

[0059] The present invention also provides the application of the aforementioned traditional Chinese medicine composition in the preparation of a medicament for treating erosion of the digestive tract tissues.

[0060] The present invention also provides a decoction for treating erosion of digestive tract tissues, which is prepared from the aforementioned traditional Chinese medicine composition.

[0061] This invention also provides a method for preparing a decoction for treating erosion of digestive tract tissues, comprising the following steps:

[0062] (1) Weigh each component according to the stated mass fractions to obtain the traditional Chinese medicine composition;

[0063] (2) Mix the Chinese herbal composition with water, soak for 25-35 minutes, decoct for 20-30 minutes, filter, and obtain filter residue and first filtrate;

[0064] (3) Mix the filter residue obtained in step (2) with water, boil for 20-30 minutes, filter, and take the filtrate to obtain the second filtrate;

[0065] (4) Combine the first and second filtrates to obtain the decoction.

[0066] In this invention, the mass ratio of the traditional Chinese medicine composition to water in step (2) is 1:2 to 4, preferably 1:3, and the soaking time in step (2) is preferably 30 min; the decoction in step (2) is to first bring it to a boil over high heat and then decoct it over medium heat, and the decoction time is preferably 25 min.

[0067] In this invention, the mass ratio of the filter residue to water in step (3) is 1:1 to 3, preferably 1:2; the decocting in step (3) is to first bring it to a boil over high heat, and then simmer it over medium heat, with the simmering time preferably being 25 minutes.

[0068] In this invention, the filtration in steps (2) to (3) is independently a 3 to 4 layer gauze filtration, preferably a 4 layer gauze filtration.

[0069] The following detailed description of the solutions provided by the present invention, in conjunction with the embodiments, should not be construed as limiting the scope of protection of the present invention.

[0070] Example 1

[0071] Weigh out 15g of Dioscorea opposita, 20g of Smilax glabra, 25g of Salvia miltiorrhiza, 15g of raw Coix lacryma-jobi, 10g of Citrus medica var. sarcodactylis, 20g of Citrus reticulata peel, 20g of Trichosanthes kirilowii, 5g of Polygonatum odoratum, 15g of Paeonia suffruticosa root bark, 10g of Morinda officinalis, 10g of Cistanche deserticola, 15g of Atractylodes macrocephala, 10g of fresh ginger, 5g of Bupleurum chinense and 10g of Codonopsis pilosula, and mix them to obtain a traditional Chinese medicine composition.

[0072] Mix the Chinese herbal medicine composition with water at a mass ratio of 1:3, soak for 25 minutes, bring to a boil over high heat, simmer over medium heat for 30 minutes, filter through 4 layers of gauze, and collect the filtrate to obtain the first filtrate.

[0073] Add twice the weight of water to the filter residue, bring to a boil over high heat, simmer over medium heat for 20 minutes, filter through 4 layers of gauze, and collect the filtrate to obtain the second filtrate.

[0074] Combine the first and second filtrates to obtain the decoction.

[0075] Example 2

[0076] Weigh out 25g of Dioscorea opposita, 15g of Smilax glabra, 20g of Salvia miltiorrhiza, 10g of raw Coix lacryma-jobi, 15g of Citrus medica var. sarcodactylis, 15g of Citrus reticulata peel, 10g of Trichosanthes kirilowii, 15g of Polygonatum odoratum, 5g of Paeonia suffruticosa, 5g of Morinda officinalis, 15g of Cistanche deserticola, 10g of Atractylodes macrocephala, 5g of fresh ginger, 10g of Bupleurum chinense and 5g of Codonopsis pilosula, and mix them to obtain a traditional Chinese medicine composition.

[0077] Mix the Chinese herbal medicine composition with water at a mass ratio of 1:4, soak for 25 minutes, bring to a boil over high heat, simmer over medium heat for 30 minutes, filter through 4 layers of gauze, and collect the filtrate to obtain the first filtrate.

[0078] Add water equal to the weight of the filter residue, bring to a boil over high heat, simmer over medium heat for 20 minutes, filter through 4 layers of gauze, and collect the filtrate to obtain the second filtrate.

[0079] Combine the first and second filtrates to obtain the decoction.

[0080] Example 3

[0081] Weigh out 20g of Dioscorea opposita, 25g of Smilax glabra, 15g of Salvia miltiorrhiza, 20g of raw Coix lacryma-jobi, 20g of Citrus medica var. sarcodactylis, 10g of Citrus reticulata peel, 15g of Trichosanthes kirilowii, 10g of Polygonatum odoratum, 10g of Paeonia suffruticosa, 15g of Morinda officinalis, 5g of Cistanche deserticola, 5g of Atractylodes macrocephala, 15g of fresh ginger, 15g of Bupleurum chinense and 15g of Codonopsis pilosula, and mix them to obtain a traditional Chinese medicine composition.

[0082] Mix the Chinese herbal medicine composition with water at a mass ratio of 1:2, soak for 35 minutes, bring to a boil over high heat, simmer over medium heat for 20 minutes, filter through 4 layers of gauze, and collect the filtrate to obtain the first filtrate.

[0083] Add twice the weight of water to the filter residue, bring to a boil over high heat, simmer over medium heat for 20 minutes, filter through 4 layers of gauze, and collect the filtrate to obtain the second filtrate.

[0084] Combine the first and second filtrates to obtain the decoction.

[0085] Application Example 1

[0086] Mr. Ding*, male, 43 years old, works as a lawyer, has many friends and social engagements, and drinks alcohol more than 3 times a week. His gastrointestinal results during a physical examination in March 2016 were not ideal. The gastroscopy showed duodenitis, reflux esophagitis (LA-A grade), chronic inflammation of the gastric antrum mucosa (mildly active), and Helicobacter pylori positive. (The physical examination center did not provide a complete gastroscopy report, only a summary of the examination results.) Figure 1 (As shown). After the physical examination, my work rhythm remained unchanged, and I couldn't control my social engagements. I felt my gastrointestinal symptoms were getting worse. Although I used Western medicine to control Helicobacter pylori, the effect was not obvious. At the end of 2019, I started taking the decoction of Example 1. I took the medicine intermittently, for a total of one year. During the medication period, I did not reduce my social engagements or drinking, and my workload did not decrease. I felt that my health did not continue to decline and even improved slightly. After stopping the medication for a period of time, a follow-up gastroscopy in April 2022 showed no abnormalities in the esophagus and duodenum. The gastric fundus and body mucosa were swollen, with scattered punctate redness. The gastric antrum mucosa was swollen, with red and white patches, mainly red. Examination conclusion: Chronic superficial gastritis (moderate) ( Figure 2 It is evident that, even without proper coordination, the solution of this invention can still repair and improve relevant tissues.

[0087] Application Example 2

[0088] Ding Rong, female, 45 years old, a senior executive in a company, with frequent business entertainment requiring both mental and physical exertion. A gastroscopy in November 2019 showed multiple patchy erosions in the antral mucosa, while other gastric tissue was in relatively good condition. Figure 3 In December 2019, I began treatment with the decoction from Example 1. I continued working as usual and maintained a good diet. After six months of continuous use, I felt a significant improvement in my overall health. Starting in the third month, my stomach no longer experienced any discomfort. After six months of continued use, I felt much better and discontinued treatment. A follow-up gastroscopy was performed in December 2020, six months later. Figure 4 The results showed patchy congestion of the gastric antrum mucosa, with no abnormalities observed in other tissues. It is evident that after consuming this formula, the previously eroded gastric tissue has been largely repaired, with only slight inflammation remaining.

[0089] Application Example 3

[0090] Duan*ping, female, 42 years old, has a simple but fulfilling job and a stable and harmonious family life. Due to unfavorable family genes, she has been physically weak since childhood and pays special attention to her health. A gastroscopy in July 2022 showed (…). Figure 5 The esophagus and cardia showed no abnormalities; the gastric fundus mucus was yellow and scant; the gastric body mucosa was red and white, predominantly red, with multiple old blood crusts visible; the gastric angle was normal; the gastric antrum mucosa was red and white, predominantly red, with umbilical erosions visible; the pylorus was round and opened and closed well; the duodenal bulb mucosa was red and eroded; the diagnosis was chronic non-atrophic gastritis with erosion and duodenitis. From July 2022 to December 2022 and from March 2024 to September 2024, the decoction of Example 2 was used for a total of 12 months to systematically maintain and improve the digestive system's function and repair gastrointestinal tissue. The reason for taking it again in 2024 was related to the significant decline in physical condition after multiple COVID-19 infections in 2023. In order to improve physical function in time, the decoction of Example 2 was used again for maintenance after the Spring Festival in 2024. In November 2024, gastroscopy showed ( Figure 6 The esophagus and cardia showed no abnormalities; the gastric fundus mucus was yellow and scant; the gastric body mucosa was red and white, predominantly white; the gastric angle was normal; the gastric antrum mucosa was red and white, predominantly white; the pylorus was round and opened and closed well; no abnormalities were found in the duodenal bulb and descending part. The diagnosis was chronic atrophic gastritis (C2). It is evident that after consuming the formula of this invention, the original erosion of the gastric and duodenal tissues was basically repaired. The individual's self-perception is now very stable, and there is no longer any fear regarding their future health.

[0091] Application Example 4

[0092] Gu*ying, female, 58 years old, had suffered from stomach discomfort for many years, frequent hiccups, and often experienced hypoglycemia due to stomach discomfort, frequently feeling shivering and cold at night due to hypoglycemia. A gastroscopy performed in May 2023 showed (…). Figure 7 The gastric body mucosa was congested and edematous, with enlarged folds; the gastric antrum mucosa was red and white, predominantly white, with normal peristalsis; the duodenal bulb mucosa was normal, with a mucosal bulge above the descending papilla. The examination conclusion was: chronic atrophic gastritis (C1), duodenal bulge, and accessory papilla considered. The patient started using the decoction from Example 1 in June 2023. The first month's treatment went well, but the subsequent one-month prescription took two months to complete. The patient persisted until January 2024, having used a four-month supply. Feeling significant improvement, the patient stopped taking the Chinese medicine. A follow-up gastroscopy on May 30, 2024, showed (…). Figure 8The mucosa of the lower curvature of the stomach—the angle of the stomach—and the antrum is red and white, predominantly white, showing patchy congestion. No obvious abnormalities were observed in the duodenal bulb and the descending part. Diagnosis: Chronic gastritis (Honmura-Takemoto type C2), suggesting a previous *Helicobacter pylori* infection. It is evident that the decoction of this invention helps improve the swelling of the descending part of the duodenum. However, due to insufficient use, the improvement in gastric tissue is not significant. I feel my gastric function is already very good; I rarely belch and have not experienced nocturnal hypoglycemia. Due to certain financial constraints, I can only consider taking the medication regularly every two years.

[0093] Application Example 5

[0094] Zhong*hua, male, 71 years old, a soldier who participated in the Sino-Vietnamese War, suffered multiple injuries, including the loss of his gallbladder and appendix. After retirement, he continued to contribute to local economic development through various coordination efforts, maintaining a heavy workload and numerous social engagements; he also has a high alcohol tolerance. A 2020 physical examination revealed several hidden health issues, including a gastroscopy showing (…). Figure 9 The esophageal mucosa was rough with granular hyperplasia; the cardia opened and closed well, the EG line was unclear, and the mucosa was rough; the gastric fundus mucosa was significantly rough, with clear and small amounts of mucus; the gastric body mucosa was rough; the gastric angle mucosa was rough in an arc shape; the gastric antrum mucosa was rough, with alternating red and white patches, predominantly red, with widespread raised and flat erosions, and the biopsy tissue was tough. Conclusion: Chronic erosive gastritis of the stomach, with granular hyperplasia of the esophagus. The patient began taking the decoction from Example 1 for digestive system maintenance in 2020. The symptoms of esophageal reflux improved rapidly. Because of the psychological stress of gastroscopy for the elderly, a follow-up examination was not scheduled until September 2023. The gastroscopy showed (…). Figure 10 The esophageal mucosa showed no abnormalities. The cardia opened and closed well, and the EG line was clear. The gastric fundus mucosa showed no abnormalities, and the mucus lake was clear. The gastric body mucosa was red and white, predominantly red, with swollen and tortuous mucosal folds, increased exudation, and mottled congestion. The gastric angle was arc-shaped, with a few intestinal metaplasia visible. The gastric antrum mucosa was red and white, predominantly red, with scattered erosions. Conclusion: Chronic superficial erosive gastritis. It is evident that the decoction of this invention helped to thoroughly improve the esophagus, significantly improve the gastric mucosa, and repair the extensive raised erosions in the gastric antrum. The incomplete improvement was largely related to alcohol consumption. However, the soldier's hearty drinking habits were difficult to control, and strict control could not be imposed. The individual and their family are very happy to have achieved such improvement without abstaining from alcohol.

[0095] Application Example 6

[0096] Zou*jin, female, 37 years old, has been frail and sickly since childhood. She underwent cholecystectomy and bilateral breast nodule removal. In July 2023, a gastroscopy revealed (…). Figure 11The esophagus and cardia were normal. A broad-based polyp measuring approximately 0.4*0.4cm was observed in the gastric fundus (removed by forceps). The gastric body mucosa was smooth and of normal color, with no masses or ulcers observed. The mucus pool was yellowish-green and of moderate quantity. The gastric angle notch mucosa was smooth and without white coating. The gastric antrum mucosa was red and white, predominantly red, with congestion, edema, and scattered erosions. The pylorus was round and well-opened. The duodenal bulb mucosa was congested and edematous. Diagnosis: Gastric polyp (removed by forceps); chronic superficial gastritis with erosion and bile reflux; duodenitis. In September 2023, the decoction from Example 3 was used for comprehensive conditioning, hoping to improve overall health. The total treatment time was 6 months, with 2 months of medication for gastrointestinal maintenance. In March 2024, after feeling improvement, treatment was discontinued. A gastroscopy was performed in July 2024, showing ( Figure 12 Examination revealed no abnormalities in the esophagus and cardia; the gastric fundus mucosa was smooth and of normal color, with no masses or ulcers observed; the mucus pool was turbid and yellowish-green in moderate quantity; a 0.3*0.4cm polyp in the gastric body was removed; the gastric angle notch mucosa was smooth and without white coating; the gastric antrum mucosa was red and white, predominantly red, with congestion, edema, and scattered erosions; the pylorus was round and well-opened; no abnormalities were observed in the duodenal bulb and descending part. Diagnosis: Gastric polyp (removed); chronic superficial gastritis with erosion and bile reflux. It is evident that this patented formula significantly improves duodenitis. However, due to my congenital deficiencies, the duration of use of this formula was insufficient; although gastrointestinal function improved, it was not enough to fully repair the stomach.

[0097] As can be seen from the above embodiments, the present invention provides a traditional Chinese medicine composition, decoction, and preparation method for treating digestive tract tissue erosion. The traditional Chinese medicine composition of the present invention comprises the following components in parts by weight: 15-25 parts of Dioscorea opposita, 15-25 parts of Smilax glabra, 15-25 parts of Salvia miltiorrhiza, 10-20 parts of raw Coix lacryma-jobi, 10-20 parts of Citrus medica var. sarcodactylis, 10-20 parts of Citrus reticulata peel, 10-20 parts of Trichosanthes kirilowii, 5-15 parts of Polygonatum odoratum, 5-15 parts of Paeonia suffruticosa, 5-15 parts of Morinda officinalis, 5-15 parts of Cistanche deserticola, 5-15 parts of Atractylodes macrocephala, 5-15 parts of fresh ginger, 5-15 parts of Bupleurum chinense, and 5-15 parts of Codonopsis pilosula. The traditional Chinese medicine composition of the present invention has the effects of strengthening the spleen, regulating qi, tonifying the kidneys, and regulating the liver. The formula is safe, non-toxic, and can be taken continuously. Although the treatment time is relatively long, it can comprehensively improve bodily functions, more completely repair digestive tract tissues, and slow down further tissue damage and malignant transformation.

[0098] The above description is only a preferred embodiment of the present invention. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the principle of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. A Chinese medicine composition for treating digestive tract tissue erosion, characterized in that: The composition includes the following components in parts by weight: 15-25 parts of yam, 15-25 parts of wild yam, 15-25 parts of salvia miltiorrhiza, 10-20 parts of raw coix seeds, 10-20 parts of citrus hand, 10-20 parts of tangerine peel, 10-20 parts of trichosanthes, 5-15 parts of polygonatum, 5-15 parts of moutan bark, 5-15 parts of morinda officinalis, 5-15 parts of cistanche, 5-15 parts of atractylodes, 5-15 parts of ginger, 5-15 parts of bupleurum, and 5-15 parts of codonopsis.

2. The Chinese medicine composition according to claim 1, characterized in that: The composition includes the following components in parts by weight: 17-23 parts of yam, 17-23 parts of wild yam, 17-23 parts of salvia miltiorrhiza, 12-18 parts of raw coix seeds, 12-18 parts of citrus hand, 12-18 parts of tangerine peel, 12-18 parts of trichosanthes, 7-13 parts of polygonatum, 7-13 parts of moutan bark, 7-13 parts of morinda officinalis, 7-13 parts of cistanche, 7-13 parts of atractylodes, 7-13 parts of ginger, 7-13 parts of bupleurum, and 7-13 parts of codonopsis.

3. The Chinese medicine composition according to claim 2, characterized in that: The composition includes the following components in parts by weight: 20 parts of yam, 20 parts of smilax glabra, 20 parts of salvia miltiorrhiza, 15 parts of raw coix seeds, 15 parts of citron, 15 parts of dried tangerine peel, 15 parts of trichosanthes, 10 parts of polygonatum, 10 parts of moutan bark, 10 parts of morinda officinalis, 10 parts of cistanche, 10 parts of atractylodes, 10 parts of ginger, 10 parts of bupleurum, and 10 parts of codonopsis.

4. The Chinese medicine composition according to any one of claims 1 to 3, characterized in that: The bergamot is a Cantonese bergamot; The tangerine peel is Guang tangerine peel; The Trichosanthes kirilowii is the whole Trichosanthes kirilowii.

5. Use of the Chinese medicine composition according to any one of claims 1 to 4 in the preparation of a medicament for treating digestive tract tissue erosion.

6. A decoction for treating digestive tract tissue erosion, characterized in that: The invention is prepared from the Chinese medicine composition according to any one of claims 1 to 4.

7. A method for preparing a decoction for treating digestive tract tissue erosion, characterized in that: The steps include: (1) Weighing each component according to the mass fractions described in any one of claims 1 to 4 to obtain a Chinese medicine composition; (2) mixing the Chinese medicine composition with water, soaking for 25 to 35 minutes, decocting for 20 to 30 minutes, filtering to obtain a filter residue and a first filtrate; (3) mixing the filter residue obtained in step (2) with water, boiling for 20 to 30 minutes, filtering, and collecting the filtrate to obtain a second filtrate; (4) The first filtrate and the second filtrate are combined to obtain a decoction.

8. The preparation method according to claim 7, characterized in that: The mass ratio of the Chinese medicine composition mixed with water in step (2) is 1:2-4.

9. The preparation method according to claim 8, characterized in that: The mass ratio of the filter residue and water mixed in step (3) is 1:1-3.

10. The preparation method according to any one of claims 7 to 9, characterized in that: The filtration described in step (2) to step (3) is independently 3 to 4 layers of gauze filtration.

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