Bacteriostatic adult paper diaper containing sustained-release gel beads and production process thereof

Abstract

The invention discloses a bacteriostatic adult paper diaper containing slow-release gel beads and a production process thereof, the bacteriostatic adult paper diaper comprises a surface layer, a composite flow guide layer, a composite core body and a bottom layer which are compounded in sequence, and a plurality of bacteriostatic flow guide strips in the width direction of the paper diaper are arranged in the flow guide layer; the composite core is prepared by mixing slow-release gel beads, high-molecular water-absorbent resin and fluff pulp, and the manufacturing method of the antibacterial adult paper diaper comprises the following steps of S1, preparing the antibacterial flow guide strips, S2, preparing the slow-release gel beads, S3, preparing the composite flow guide layer and the composite core body, and S4, sequentially compounding the surface layer, the composite flow guide layer, the composite core body and the bottom layer to obtain the antibacterial adult paper diaper. According to the paper diaper, the bacteriostatic flow guide strips are arranged in the composite flow guide layer of the paper diaper, and the slow-release gel beads are mixed in the composite core body, so that the dual bacteriostatic effect is achieved, the bacteriostatic flow guide strips can form an effective bacteriostatic barrier on the surface of the paper diaper, and meanwhile, the bacteriostatic components in the slow-release gel beads can provide lasting bacteriostatic protection for the core body.

Description

Technical Field

[0001] The invention relates to the field of diaper technology, and in particular to an antibacterial adult diaper containing slow-release gel beads and a production process thereof. Background Art

[0002] In recent years, with the intensification of the global aging trend, the market demand for adult diapers has continued to grow. This demand growth is mainly due to the increase in the number of elderly people and the problems of urinary incontinence or mobility problems caused by elderly diseases such as stroke, dementia, and diabetes. Adult diapers add functional slow-release beads inside to improve the absorbency and antibacterial properties of adult diapers, thereby enhancing the function of the product. The slow-release beads are a microspherical substance that can slowly release the essential oil or plant extract inside it, including the capsule core and the capsule wall. By controlling the release rate of the contents of the capsule core, the slow release effect is achieved. The slow-release bead technology is applied to the release of antibacterial ingredients to achieve a lasting and effective antibacterial effect. The slow-release beads can control the release rate and stability of the slow-release beads by adjusting the composition and preparation process of the capsule wall material. Since the slow-release beads can slowly release the essential oil or plant extract inside them, they can maintain the antibacterial effect for a long time. This not only helps to reduce the growth and reproduction of bacteria inside diapers, but also reduces the risk of skin inflammation caused by bacterial infection.

[0003] Based on the above situation, in the prior art, a patent with application number CN202010243533.8 discloses a method for preparing skin care diapers, which solves the problem that the prior art diapers are insufficiently antibacterial and easily cause skin discomfort, including the preparation of a liquid-permeable surface layer, an absorption layer and a leakage-proof bottom layer. The liquid-permeable surface layer is stacked from top to bottom with an upper non-woven fabric, an antibacterial layer and a lower non-woven fabric, the upper non-woven fabric is a polylactic acid non-woven fabric, the lower non-woven fabric is an ES non-woven fabric, the antibacterial layer is a microcapsule, the microcapsule is made of chitosan and gum arabic as wall materials, and tea oil, witch hazel extract and dandelion extract as core materials. One side of the ES non-woven fabric is sprayed with a hydrophilic finishing liquid, and then the microcapsules are evenly sprayed on the side of the ES non-woven fabric that is not sprayed with the hydrophilic finishing liquid, and the polylactic acid non-woven fabric is covered on the microcapsules. The liquid-permeable surface layer is obtained after hot-melt adhesive bonding.

[0004] The skin care diaper has microcapsules in the liquid permeable surface layer, which gives the diaper certain antibacterial properties. However, there are also some limitations. As part of the breathable surface layer, the microcapsules may be damaged by external factors such as friction and pressure during use, which will cause the release of antibacterial components to become unstable, thereby affecting its antibacterial effect. In addition, the stability and durability of the microcapsules are also limited. More importantly, since the microcapsules are only set in the liquid permeable surface layer, their antibacterial effect is mainly limited to the surface of the diaper, and the core is the main absorption area for urine and other pollutants. If it is not subjected to additional antibacterial treatment, the bacterial growth in the core may not be fully inhibited. Therefore, there is still room for improvement in the antibacterial performance of this diaper. Summary of the invention

[0005] In view of the technical defects existing in the background technology, the present invention proposes an antibacterial adult diaper containing slow-release gel beads and a production process thereof, which solves the above technical problems and meets the actual needs. The specific technical solution is as follows: An antibacterial adult diaper containing slow-release gel beads, comprising a surface layer, a composite guide layer, a composite core and a bottom layer which are compounded in sequence; a plurality of antibacterial guide strips equidistantly arranged along the width direction of the diaper are arranged inside the guide layer; the composite core is prepared by mixing slow-release gel beads, a polymer absorbent resin and fluff pulp; the antibacterial guide strips are composed of a composite chitosan gel strip and a gelatin outer layer coated on the surface of the composite chitosan gel strip; the slow-release gel beads are composed of an inner slow-release bead glue liquid and a composite gelatin protective shell coated on the inner slow-release bead glue liquid; the inner slow-release bead glue liquid contains the following components in weight fractions: 20-30 parts of wormwood extract, 20-30 parts of lithospermum extract, 20-30 parts of tea polyphenols, 1-5 parts of xanthan gum, 60-100 parts of deionized water and 1-5 parts of calcium chloride.

[0006] Furthermore, when the surface layer and the composite guide layer are formed, the surface layer is bonded to the area between the antibacterial guide strips of the composite guide layer.

[0007] Furthermore, the interval between adjacent antibacterial guide strips inside the composite guide layer is 6-10 mm, and the ratio of the slow-release beads to the high molecular water-absorbing resin in the fluff pulp is (0.5-1):1.

[0008] A production process of antibacterial adult diapers containing slow-release gel beads, comprising the following steps: S1, prepare antibacterial guide strip, dissolve chitosan in acetic acid solution, adjust pH, then add epoxy quaternary ammonium salt and dialdehyde polyethylene glycol in sequence under heating and stirring conditions, ultrasonicate and react for a period of time, then add a certain amount of sodium hydroxide solution to obtain a chitosan mixed solution, pour the chitosan mixed solution into a strip mold, let it stand, and after the chitosan mixed solution solidifies, obtain a strip intermediate, dialyze the strip intermediate with deionized water for 24 hours to obtain a composite chitosan gel strip, place the composite chitosan gel strip in a gelatin solution of a certain concentration, then separate the composite chitosan gel strip and place it in a low temperature environment to solidify the gelatin to form a gelatin outer layer to obtain an antibacterial guide strip; S2, preparing sustained-release gel beads, mixing wormwood extract, lithospermum officinale extract, tea polyphenols, xanthan gum and calcium chloride in deionized water, heating at 30-40°C to dissolve, obtaining inner sustained-release gel solution, dissolving gelatin and sodium alginate in deionized water under heating conditions, cooling to room temperature, then adding gelatin particles, mixing evenly to obtain mixed gelatin solution, slowly dripping the inner sustained-release gel solution into the mixed gelatin solution, reacting and curing to form a composite gelatin protective shell, filtering and separating, and drying the surface to obtain sustained-release gel beads; S3, bonding a number of antibacterial guide strips to the surface of the non-woven fabric of the guide layer at equal intervals in the width direction of the diaper by means of an adhesive to obtain a composite guide layer, and mixing the slow-release gel beads, the polymer absorbent resin and the fluff pulp to obtain a composite core; S4, compounding the surface layer, the composite guide layer, the composite core body and the bottom layer in sequence to obtain an antibacterial adult diaper.

[0009] Furthermore, in step S1, the deacylation degree of the chitosan is 75-80%, the molecular weight of the chitosan is 150,000-170,000 Da, the epoxy quaternary ammonium salt is selected from any one of glycidyltrimethylammonium chloride and hexyldimethylglycidylammonium chloride, the molecular weight of the bisaldehyde polyethylene glycol is 10,000-20,000, and the mass ratio of the chitosan, epoxy quaternary ammonium salt and bisaldehyde polyethylene glycol is 1:0.2:(0.5-1).

[0010] Further, in step S1, chitosan is dissolved in 40-50 times the volume of 1% acetic acid solution at 60°C and a stirring speed of 400 rpm, and then a 1M sodium hydroxide solution is used to adjust the pH to 5.5-6.5, and then the temperature is increased to 70-90°C, and epoxy quaternary ammonium salt and dialdehyde polyethylene glycol are added in sequence, ultrasonicated for 1-2h, and then 0.5-2 times the volume of 2% sodium hydroxide solution is added to obtain a chitosan mixed solution.

[0011] Furthermore, in step S1, the composite chitosan gel strip has a width of 2-3 mm and a thickness of 1-1.5 mm. The composite chitosan gel strip is placed in a 20% gelatin aqueous solution, and then the composite chitosan gel strip is separated and placed in a low temperature environment of 5°C to allow the gelatin to solidify to form a gelatin outer layer with a thickness of 0.1-0.3 mm.

[0012] Furthermore, in step S2, the wormwood extract is wormwood essential oil, and the lithospermum extract is a viscous paste extracted with lithospermum alcohol.

[0013] Furthermore, in step S2, 50 parts of gelatin and 10 parts of sodium alginate are dissolved in 100 parts of deionized water at 30° C. under heating conditions, cooled to room temperature, and then 5 parts of gelatin particles with a particle size of 0.05-0.1 mm are added and mixed evenly to obtain a mixed gelatin solution.

[0014] Furthermore, in step S2, when the internal sustained-release bead gel solution is slowly dripped into the mixed gelatin solution, the diameter of the spheres when the mixed gelatin solution is dripped is controlled to be 2-3 mm.

[0015] The beneficial effects of the present invention are: The present invention achieves a dual antibacterial effect by arranging an antibacterial guide strip in the composite guide layer of the diaper, and mixing slow-release gel beads in the composite core. The composite chitosan gel strip in the antibacterial guide strip works synergistically with the gelatin outer layer to form an effective antibacterial barrier on the surface of the diaper. At the same time, the composite core is prepared by mixing slow-release gel beads, high molecular water-absorbing resin and fluff pulp, which can quickly absorb and lock urine to keep the inside of the diaper dry and comfortable. The herbal ingredients such as wormwood extract, lithospermum extract, tea polyphenols in the slow-release gel beads can be slowly released to provide lasting antibacterial protection for the core, significantly reducing the risk of bacterial growth. The antibacterial guide strip not only has an antibacterial function, but also can effectively guide urine to diffuse to a wider area, reducing excessive accumulation of urine in a certain area of ​​the diaper, thereby improving the diversion performance of the diaper. DETAILED DESCRIPTION

[0016] The implementation mode of the present invention is described below in conjunction with relevant embodiments. The implementation mode of the present invention is not limited to the following embodiments, and the present invention relates to relevant necessary components in the technical field, which should be regarded as the known technology in the technical field and can be known and mastered by the technical personnel in the technical field.

[0017] An antibacterial adult diaper containing slow-release gel beads, comprising a surface layer, a composite guide layer, a composite core and a bottom layer which are compounded in sequence; a plurality of antibacterial guide strips equidistantly arranged along the width direction of the diaper are arranged inside the guide layer; the composite core is prepared by mixing slow-release gel beads, a polymer absorbent resin and fluff pulp; the antibacterial guide strips are composed of a composite chitosan gel strip and a gelatin outer layer coated on the surface of the composite chitosan gel strip; the slow-release gel beads are composed of an inner slow-release bead glue liquid and a composite gelatin protective shell coated on the surface of the inner slow-release bead glue liquid; the inner slow-release bead glue liquid contains the following components in weight fractions: 20-30 parts of wormwood extract, 20-30 parts of lithospermum extract, 20-30 parts of tea polyphenols, 1-5 parts of xanthan gum, 60-100 parts of water and 1-5 parts of calcium chloride.

[0018] As one of the preferred embodiments of the present invention, in the diaper structure of the present invention, the interval between adjacent antibacterial guide strips on the surface of the guide layer non-woven fabric is 6-10 mm, and the ratio of the slow-release beads and the polymer water-absorbent resin in the fluff pulp is (0.5-1): 1. Specifically, the ratio of the slow-release beads and the polymer water-absorbent resin in the fluff pulp is 0.5:1, the interval between adjacent antibacterial guide strips is 6 mm, and the total mass of the slow-release beads and the polymer water-absorbent resin to the mass of the fluff pulp is 1:3.

[0019] As one of the preferred embodiments of the present invention, in the diaper structure of the present invention, when the surface layer and the composite guide layer are combined, the surface layer is bonded to the area between the antibacterial guide strips of the composite guide layer.

[0020] The present invention achieves a dual antibacterial effect by arranging an antibacterial guide strip in the composite guide layer of the diaper, and mixing slow-release gel beads in the composite core. The composite chitosan gel strip in the antibacterial guide strip works synergistically with the gelatin outer layer to form an effective antibacterial barrier on the surface of the diaper. At the same time, the herbal ingredients such as wormwood extract, lithospermum extract, tea polyphenols, etc. in the slow-release gel beads can be slowly released to provide lasting antibacterial protection for the core, significantly reducing the risk of bacterial growth. The antibacterial guide strip not only has an antibacterial function, but also can effectively guide urine to diffuse to a wider area, reducing excessive accumulation of urine in a certain area of ​​the diaper, thereby improving the diversion performance of the diaper. The composite core is prepared by mixing slow-release gel beads, high molecular water-absorbent resin and fluff pulp, which can quickly absorb and lock urine to keep the inside of the diaper dry and comfortable.

[0021] The diaper of the present invention is provided with a plurality of antibacterial guide strips along the width direction of the diaper inside the guide layer, and the interval between adjacent antibacterial guide strips on the non-woven fabric surface of the guide layer is 6 mm. The evenly distributed guide strips ensure that urine can flow smoothly to the absorption area of ​​the entire diaper, and the antibacterial guide strips also have the effect of preventing bedsores. The antibacterial guide strips arranged at intervals can enhance the surface concave-convex effect, so that the surface of the surface layer in contact with the skin fluctuates, which has the advantages of ventilation and air exchange, and transfer of the body's stress points. Long-term use can play a role in preventing and treating bedsores. The composite core is prepared by mixing slow-release beads, high molecular water-absorbing resin and fluff pulp. The ratio of slow-release beads and high molecular water-absorbing resin in the fluff pulp is 0.5:1, which not only ensures that the core has sufficient water absorption capacity, but also avoids the stiffness and discomfort of the core caused by excessive water-absorbing resin.

[0022] The surface layer is bonded to the area between the antibacterial guide strips of the composite guide layer. On the one hand, it can further fix the antibacterial guide strips, and on the other hand, it can form grooves on the surface layer, which improves the wearing comfort and ensures that urine can smoothly penetrate into the composite guide layer and the core through the surface layer. The antibacterial guide strip is composed of a composite chitosan gel strip and a gelatin outer layer coated on the surface of the gel strip. Chitosan, as a natural high molecular weight polysaccharide, has good antibacterial properties and can destroy the cell walls and cell membranes of bacteria, thereby achieving the purpose of antibacterial. By reacting chitosan with epoxy quaternary ammonium salt and dialdehyde polyethylene glycol, a composite chitosan gel strip with stronger antibacterial properties is obtained. The coating of the gelatin outer layer not only improves the stability of the gel strip, but also further enhances its antibacterial effect.

[0023] The sustained-release gel beads are composed of an inner sustained-release bead gel and a composite gelatin protective shell coated on the surface of the sustained-release beads. The inner sustained-release bead gel contains ingredients such as wormwood extract, lithospermum extract, tea polyphenols, xanthan gum, and hydrated calcium chloride. The wormwood extract, lithospermum extract, tea polyphenols, etc. have good antibacterial properties. During the preparation of the sustained-release gel beads, by controlling the composition and proportion of the inner sustained-release bead gel, as well as parameters such as the dripping speed of the mixed gelatin solution and the diameter of the sphere, sustained-release gel beads with long-lasting antibacterial effects are obtained. These sustained-release beads slowly release herbal ingredients in the core, providing long-lasting antibacterial protection for the core.

[0024] In the present invention, the interlayer material is bonded together between the surface layer, the composite guide layer, the composite core and the bottom layer by an adhesive. Regarding the selection of the surface layer, the composite guide layer, the covering cloth of the composite core and the non-woven fabric of the bottom layer, the surface layer is the part of the diaper that is in direct contact with the user's skin, so the non-woven fabric is required to be soft, skin-friendly and breathable. The non-woven fabric of the surface layer can be selected from hot air non-woven fabric or SMS non-woven fabric with good softness, air permeability and moisture absorption. The main function of the guide layer is to guide urine to diffuse rapidly to the entire absorption area of ​​the diaper, so the non-woven fabric is required to have good flow conduction performance and a certain strength. The common non-woven fabric of the guide layer can be selected from spunbond non-woven fabric or perforated non-woven fabric. When the composite core is in use, the composite core is used in conjunction with the covering cloth. The covering cloth is required to have good water absorption, air permeability and softness. The covering cloth can be selected from hot air non-woven fabric or SMS or SMMS non-woven fabric, and the bottom layer uses a composite material of breathable PE film and non-woven fabric.

[0025] The present invention provides a production process of antibacterial adult diapers containing slow-release gel beads, comprising the following steps: S1. Prepare an antibacterial guide strip. Dissolve chitosan in an acetic acid solution, adjust the pH, and then add epoxy quaternary ammonium salt and dialdehyde polyethylene glycol in sequence under heating and stirring conditions, sonicate and react for a period of time, and then add a certain amount of sodium hydroxide solution to obtain a chitosan mixed solution. Pour the chitosan mixed solution into a strip mold and let it stand. After the chitosan mixed solution solidifies, a strip intermediate is obtained. The strip intermediate is dialyzed with deionized water for 24 hours to obtain a composite chitosan gel strip. The composite chitosan gel strip is placed in a gelatin solution of a certain concentration. The composite chitosan gel strip is then separated and placed in a low temperature environment to solidify the gelatin to form a gelatin outer layer to obtain an antibacterial guide strip.

[0026] S2. Prepare sustained-release gel beads. Mix wormwood extract, lithospermum officinale extract, tea polyphenols, xanthan gum and calcium chloride in deionized water, heat at 30-40°C to dissolve, and obtain inner sustained-release gel solution. Dissolve gelatin and sodium alginate in deionized water under heating conditions, cool to room temperature, and then add gelatin particles. Mix well to obtain mixed gelatin solution. Slowly drop the inner sustained-release gel solution into the mixed gelatin solution, react and solidify to form a composite gelatin protective shell, filter and separate, and dry the surface to obtain sustained-release gel beads.

[0027] S3. Bond several antibacterial guide strips to the surface of the non-woven fabric of the guide layer at equal intervals in the width direction of the diaper by an adhesive to obtain a composite guide layer, and mix the slow-release beads, polymer absorbent resin and fluff pulp to prepare a composite core.

[0028] S4, compounding the surface layer, the composite guide layer, the composite core body and the bottom layer in sequence to obtain an antibacterial adult diaper.

[0029] The invention dissolves chitosan in an acetic acid solution, adjusts the pH value to make it in a suitable dissolved state, then, under heating and stirring conditions, the amino groups on the chitosan molecular chain react with the glycidyl group of the epoxy quaternary ammonium salt and the aldehyde group of the dialdehyde polyethylene glycol to form modified chitosan, and enhances the antibacterial property of the chitosan through chemical modification, pours the modified chitosan solution into a strip mold, and allows it to stand and solidify to form a strip intermediate, and removes unreacted chemical substances and impurities through deionized water dialysis to obtain a pure composite chitosan gel strip, and then places the composite chitosan gel strip in a gelatin solution and solidifies it at low temperature. A gelatin outer layer is formed to obtain an antibacterial guide strip. The gelatin outer layer of the antibacterial guide strip increases the flexibility and processability of the antibacterial guide strip on the one hand, and on the other hand, when the diaper is in use, the gelatin outer layer is softened by body temperature and rubs against the non-woven fabric of the surface layer and the non-woven fabric of the composite guide layer, thereby exposing the composite chitosan gel strip. The composite chitosan gel strip in the antibacterial guide strip has enhanced antibacterial properties through chemical modification, and can play an antibacterial role between the surface layer and the composite guide layer. At the same time, the addition of the gelatin outer layer enables it to soften quickly and rub against the non-woven fabric when in use, exposing the composite chitosan gel strip, further enhancing the antibacterial effect.

[0030] When preparing the sustained-release gel beads, the wormwood extract, the lithospermum extract, the tea polyphenols, the xanthan gum and the calcium chloride are mixed in deionized water, and the mixture is heated and dissolved to obtain an inner sustained-release bead gel solution. The addition of the xanthan gum increases the viscosity of the inner sustained-release bead gel solution, which is beneficial to the formation of a stable spherical structure when the mixed gelatin solution is subsequently dropped. Under heating conditions, the gelatin and the sodium alginate are dissolved in the deionized water, and the gelatin particles are added after cooling to room temperature, and the mixture is uniformly mixed to obtain a mixed gelatin solution. The inner sustained-release bead gel solution is slowly dropped into the mixed gelatin solution, and a gelatin protective shell comprising the gelatin, the gelatin particles and the calcium alginate is formed on the surface of the inner sustained-release bead gel solution through the curing reaction of the calcium chloride and the sodium alginate. After the calcium alginate is cured, the internal structure thereof is The sustained-release beads have a porous structure, which provides a stable structure and realizes the sustained release of antibacterial and antibacterial components through the porous structure of calcium alginate. The antibacterial and antibacterial components such as wormwood extract, lithospermum extract and tea polyphenols in the sustained-release beads can be sustained-released outward through the porous structure of calcium alginate, effectively inhibiting the growth of bacteria in the composite core. When the sustained-release beads come into contact with urine or other warm liquids, the gelatin protective shell quickly disintegrates, so that the antibacterial and antibacterial components can be completely released at one time, thereby further enhancing the antibacterial effect. Adding gelatin particles to the gelatin protective shell of the sustained-release beads can further increase the structural strength of the sustained-release beads after formation, thereby ensuring the structural stability of the sustained-release beads during use.

[0031] As one of the preferred embodiments of the present invention, in step S1, the deacylation degree of the chitosan is 75-80%, the molecular weight is 150,000-170,000 Da, the epoxy quaternary ammonium salt is selected from any one of glycidyltrimethylammonium chloride and hexyldimethylglycidylammonium chloride, the molecular weight of the bisaldehyde polyethylene glycol is 10,000-20,000, and the mass ratio of the chitosan, epoxy quaternary ammonium salt and bisaldehyde polyethylene glycol is 1:0.2:(0.5-1).

[0032] As one of the preferred embodiments of the present invention, in step S1, chitosan is dissolved in 40-50 times the volume of 1% acetic acid solution at 60°C and a stirring speed of 400rpm, and then a 1M sodium hydroxide solution is used to adjust the pH to 5.5-6.5, and then the temperature is raised to 70-90°C, and glycidyltrimethylammonium chloride and dialdehyde polyethylene glycol are added in sequence, ultrasonically added for 1-2h, and then 0.5-2 times the volume of 2% sodium hydroxide solution is added to obtain a chitosan mixed solution.

[0033] Specifically, the specific preparation method of the chitosan mixed solution is as follows: at 60°C and a stirring speed of 400 rpm, 1 g of chitosan is dissolved in 45 ml of a 1.0% acetic acid solution, and then a 1 M sodium hydroxide solution is used to adjust the pH to 6.0, and then the temperature is raised to 70°C, 0.20 g of glycidyltrimethylammonium chloride and 1.0 g of dialdehyde polyethylene glycol are added in sequence, ultrasonicated for 2 h, and then a 2% sodium hydroxide solution equivalent to twice the volume of the previous mixed solution is added to obtain a chitosan mixed solution.

[0034] In the preparation method, chitosan is first dissolved in an acetic acid solution, and its amino functional groups are activated by adjusting the pH value and heating. Then, under stirring conditions, glycidyl trimethyl ammonium chloride and dialdehyde polyethylene glycol are added in sequence. The glycidyl group of glycidyl trimethyl ammonium chloride undergoes a substitution reaction with the amino group of chitosan, while the aldehyde group of dialdehyde polyethylene glycol undergoes a condensation reaction with another amino group of chitosan to generate a Schiff base structure. These reactions together constitute the formation process of the chitosan mixed solution and provide a basis for the subsequent preparation of antibacterial guide strips.

[0035] Chitosan is a natural high molecular weight polysaccharide composed of β-(1,4)-linked D-glucosamine and N-acetyl-D-glucosamine units. Chitosan has abundant amino functional groups, which can react with other compounds under appropriate conditions. The structural formula of dialdehyde polyethylene glycol is DA-PEG-DA, and the terminal aldehyde group has high activity. In the preparation method, the amino group of chitosan reacts chemically with the glycidyl group of glycidyltrimethylammonium chloride and the double terminal aldehyde group of dialdehyde polyethylene glycol.

[0036] The glycidyl part of glycidyl trimethyl ammonium chloride is prone to undergo a ring-opening reaction under heating and stirring conditions. The amino part of chitosan undergoes a substitution reaction with the product of the ring-opening of glycidyl trimethyl ammonium chloride, thereby introducing a quaternary ammonium salt into the chitosan structure, giving chitosan further antibacterial properties. The amino part of chitosan undergoes a condensation reaction with the double-terminal aldehyde group of dialdehyde polyethylene glycol to generate a Schiff base structure. The generated Schiff base structure not only enhances the stability of the polymer system, but also gives the product antibacterial properties. The nitrogen atoms in the Schiff base structure may exert antibacterial effects by interfering with the metabolic process of bacterial cells or destroying their cell membrane structures.

[0037] As one of the preferred embodiments of the present invention, in step S1, the width of the composite chitosan gel strip is 2-3 mm and the thickness is 1-1.5 mm. The composite chitosan gel strip is placed in a 20% gelatin aqueous solution, and then the composite chitosan gel strip is separated and placed in a low temperature environment of 5°C to allow the gelatin to solidify to form a gelatin outer layer with a thickness of 0.1-0.3 mm.

[0038] Specifically, in step S1, the composite chitosan gel strip has a width of 2 mm and a thickness of 1 mm. The composite chitosan gel strip is placed in a 20% gelatin aqueous solution, and then the composite chitosan gel strip is separated and placed in a low temperature environment of 5°C to solidify the gelatin to form a gelatin outer layer with a thickness of 0.1 mm. The prepared composite chitosan gel strip is placed in a prepared 20% gelatin aqueous solution, so that the gelatin solution can fully penetrate into the surface of the composite chitosan gel strip. The composite chitosan gel strip soaked in the gelatin solution is separated and placed in a low temperature environment of 5°C. Under low temperature conditions, the interaction between gelatin molecules is enhanced, and they gradually solidify and form an outer layer of gelatin. The formation of the outer layer of gelatin increases the flexibility and processability of the composite chitosan gel strip while maintaining its original antibacterial properties. This helps to make it easier to bond the composite chitosan gel strip to the non-woven fabric of the composite guide layer of the diaper during subsequent production and processing. When the diaper is in use, the outer layer of gelatin is softened by the influence of body temperature, and rubs against the non-woven fabric of the surface layer and the non-woven fabric of the composite guide layer, which helps to expose the surface of the composite chitosan gel strip, so that it can more fully contact with the surface layer and exert a better antibacterial effect.

[0039] As one of the preferred embodiments of the present invention, in step S2, the wormwood extract is wormwood essential oil, and the lithospermum extract is a viscous paste extracted with lithospermum alcohol.

[0040] As one of the preferred embodiments of the present invention, in step S2, 50 parts of gelatin and 10 parts of sodium alginate are dissolved in 100 parts of deionized water at 30°C under heating conditions, cooled to room temperature, and then 5 parts of gelatin particles with a particle size of 0.05-0.1 mm are added and mixed evenly to obtain a mixed gelatin solution.

[0041] As one of the preferred embodiments of the present invention, in step S2, when the internal sustained-release bead gelatin solution is slowly dripped into the mixed gelatin solution, the diameter of the spheres when the mixed gelatin solution is dripped is controlled to be 2-3 mm.

[0042] The specific method for preparing sustained-release gel beads of the present invention is as follows: 30 parts of wormwood extract, 30 parts of lithospermum extract, 30 parts of tea polyphenols, 5 parts of xanthan gum and 5 parts of calcium chloride are heated and dissolved in 100 parts of deionized water at 30°C, ensuring that all components are fully dissolved and mixed evenly to form an inner sustained-release bead glue solution; 50 parts of gelatin and 10 parts of sodium alginate are dissolved in 100 parts of deionized water at 30°C under heating conditions, cooled to room temperature, and then 5 parts of gelatin particles with a particle size of 0.05 mm are added and mixed evenly to obtain a mixed gelatin solution; the inner sustained-release bead glue solution is slowly dripped into the mixed gelatin solution through an injection pump; during the dripping process, the diameter of the dripped sphere is controlled to be 2-3 mm; after the inner sustained-release bead glue solution contacts the mixed gelatin solution, a curing reaction occurs to form sustained-release gel beads comprising the inner sustained-release bead glue solution and a gelatin protective shell; the formed sustained-release gel beads are filtered and separated, and surface drying treatment is performed to obtain sustained-release gel beads.

[0043] The internal sustained-release beads contain herbal ingredients such as mugwort extract, lithospermum extract and tea polyphenols. Mugwort extract is mugwort essential oil, and lithospermum extract is a viscous paste extracted from lithospermum alcohol. Mugwort essential oil, lithospermum alcohol-extracted viscous paste and tea polyphenols are released into the composite core, which can inhibit the growth of bacteria such as Staphylococcus aureus and Escherichia coli. When the sustained-release beads come into contact with urine or other warm liquids, the above-mentioned herbal ingredients can be released outward, thereby reducing the growth of bacteria in the composite core.

[0044] The calcium chloride in the inner sustained-release bead gel solution reacts with the sodium alginate in the mixed gelatin solution to form a gelatin protective shell containing gelatin, gelatin particles and calcium alginate. After the calcium alginate is solidified, its internal structure has a porous structure, which allows the herbal ingredients in the inner sustained-release beads to be slowly released outward through the porous structure. When the sustained-release beads come into contact with urine or other warm liquids, the gelatin protective shell will quickly disintegrate, so that the herbal ingredients in the inner sustained-release beads can be completely released at one time. The gelatin particles in the gelatin protective shell can further increase the structural strength of the sustained-release beads after formation, making it less likely to break or deform during use.

[0045] Example 1

[0046] At 60°C and 400rpm stirring speed, 1g chitosan was dissolved in 45ml of 1.0% acetic acid solution, and then 1M sodium hydroxide solution was used to adjust the pH to 6.0, and then the temperature was raised to 70°C, 0.20g of epoxypropyltrimethylammonium chloride and 1.0g of dialdehyde polyethylene glycol were added in sequence, ultrasonicated for 2h, and then a 2% sodium hydroxide solution equivalent to twice the volume of the previous mixed solution was added to obtain a chitosan mixed solution, the chitosan mixed solution was poured into a strip mold, and allowed to stand for solidification, the solidified strip intermediate was dialyzed with deionized water for 24 hours to obtain a composite chitosan gel strip, the composite chitosan gel strip was placed in a 20% gelatin aqueous solution to ensure that the gelatin solution fully penetrated the surface of the gel strip, the soaked gel strip was separated and placed in a low temperature environment of 5°C to solidify the gelatin to form a gelatin outer layer with a thickness of 0.1mm to obtain an antibacterial guide strip.

[0047] 30 parts of mugwort extract, 30 parts of lithospermum extract, 30 parts of tea polyphenols, 5 parts of xanthan gum and 5 parts of calcium chloride are heated and dissolved in 100 parts of deionized water at 30°C to ensure that all ingredients are fully dissolved and mixed evenly to form an inner sustained-release bead glue solution; 50 parts of gelatin and 10 parts of sodium alginate are dissolved in 100 parts of deionized water at 30°C under heating conditions, cooled to room temperature, and then 5 parts of gelatin particles with a particle size of 0.05 mm are added and mixed evenly to obtain a mixed gelatin solution; the inner sustained-release bead glue solution is slowly dripped into the mixed gelatin solution through an injection pump; during the dripping process, the diameter of the dripped sphere is controlled to be 2-3 mm; after the inner sustained-release bead glue solution contacts the mixed gelatin solution, a curing reaction occurs to form sustained-release beads comprising the inner sustained-release bead glue solution and a composite gelatin protective shell; the formed sustained-release beads are separated by filtration and surface drying is performed to obtain sustained-release beads.

[0048] Several antibacterial guide strips are bonded to the non-woven surface of the guide layer at equal intervals in the width direction of the diaper by an adhesive, and the interval between adjacent antibacterial guide strips is 6 mm. The sustained-release beads and the polymer absorbent resin are mixed in the fluff pulp at a ratio of 0.5:1, and the core forming equipment is used to form a composite core. Then a layer of non-woven fabric is coated on the surface of the composite core. Then the surface layer is bonded to the area between the antibacterial guide strips of the composite guide layer. Finally, the surface layer, the composite guide layer, the composite core and the bottom layer are compounded together in sequence to obtain the antibacterial adult diaper.

[0049] Comparative Example 1 The difference between Example 1 and Comparative Example 1 is that when preparing the antibacterial guide strip in Comparative Example 1, no epoxypropyltrimethylammonium chloride is added, and the other preparation steps are the same as those in Example 1.

[0050] Comparative Example 2 The difference between Example 1 and Comparative Example 2 is that the antibacterial guide strip in Example 1 is directly replaced by the composite chitosan gel strip in Comparative Example 2.

[0051] Comparative Example 3 The difference between Example 1 and Comparative Example 3 is that the added amounts of the mugwort extract, lithospermum officinale extract and tea polyphenols in Comparative Example 3 are all 20 parts.

[0052] Comparative Example 4 The difference between Example 1 and Comparative Example 4 is that the added amounts of the mugwort extract, lithospermum officinale extract and tea polyphenols in Comparative Example 4 are all 40 parts.

[0053] Example 1 and Comparisons 1-4 were subjected to antibacterial experiments in accordance with GB 15979-2024 "Hygiene Requirements for Disposable Sanitary Products". The test results are shown in the following table:

[0054] In Example 1, the antibacterial guide strip prepared by adding glycidyl trimethylammonium chloride has an antibacterial rate of 95.2% and 93.1% against Escherichia coli and Staphylococcus aureus, respectively. In Comparative Example 1, glycidyl trimethylammonium chloride was not added, and the antibacterial rate dropped to 92.1% and 91.5%, respectively. This shows that the addition of glycidyl trimethylammonium chloride helps to improve the antibacterial effect of the antibacterial guide strip. Glycidyl trimethylammonium chloride introduces a quaternary ammonium salt group with antibacterial effect into the chitosan structure, and the antibacterial property of the quaternary ammonium salt group is It can improve the antibacterial effect of diapers; Example 1 uses an antibacterial guide strip with a gelatin outer layer, and Comparative Example 2 directly uses a composite chitosan gel strip, and the antibacterial rate is slightly improved (95.6% for Escherichia coli and 93.9% for Staphylococcus aureus), but in the actual production process, it is found that its processing performance is poor and it is easy to break, which indicates that the addition of a gelatin outer layer may sacrifice some of the antibacterial effect to a certain extent, but significantly improves the flexibility and processing performance of the material, making the antibacterial guide strip more suitable for the production and use of diapers.

[0055] In Example 1, the addition amount of wormwood extract, lithospermum extract and tea polyphenols is 30 parts, and the antibacterial effect is good. In Comparative Example 3, the addition amount of wormwood extract, lithospermum extract and tea polyphenols is reduced to 20 parts, and the antibacterial rate decreases accordingly (Escherichia coli 91.1%, Staphylococcus aureus 90.1%). In Comparative Example 4, the addition amount of wormwood extract, lithospermum extract and tea polyphenols is increased to 40 parts. Although the antibacterial rate is improved (Escherichia coli 95.4%, Staphylococcus aureus 92.9%), the improvement is not large, which shows that within a certain range, increasing the addition amount of these natural extracts can improve the antibacterial effect, but after exceeding a certain amount, the improvement effect is no longer significant, and it brings cost pressure. After comprehensive evaluation, Example 1 achieves a good balance between antibacterial effect and processing performance, which not only ensures a high antibacterial rate, but also ensures the stability and durability of the product.

[0056] The above is only a preferred embodiment of the present invention. It should be pointed out that ordinary technicians in this technical field can make several improvements and modifications without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. An antibacterial adult diaper containing slow-release gel beads, characterized in that: It includes a surface layer, a composite guide layer, a composite core and a bottom layer which are compounded in sequence. The guide layer is provided with a plurality of antibacterial guide strips which are equidistantly arranged along the width direction of the diaper. The composite core is prepared by mixing slow-release beads, a polymer absorbent resin and fluff pulp. The antibacterial guide strips are composed of a composite chitosan gel strip and a gelatin outer layer coated on the surface of the composite chitosan gel strip. The slow-release beads are composed of an inner slow-release bead glue liquid and a composite gelatin protective shell coated in the inner slow-release bead glue liquid. The inner slow-release bead glue liquid contains the following ingredients in weight fractions: 20-30 parts of wormwood extract, 20-30 parts of lithospermum extract, 20-30 parts of tea polyphenols, 1-5 parts of xanthan gum, 60-100 parts of deionized water and 1-5 parts of calcium chloride.

2. The antibacterial adult diaper containing slow-release beads according to claim 1, characterized in that: When the surface layer and the composite guide layer are combined, the surface layer is bonded to the area between the antibacterial guide strips of the composite guide layer.

3. The antibacterial adult diaper containing slow-release beads according to claim 1, characterized in that: The interval between adjacent antibacterial guide strips inside the composite guide layer is 6-10 mm, and the ratio of the slow-release beads to the high molecular water-absorbing resin in the fluff pulp is (0.5-1):

1.

4. A production process for antibacterial adult diapers containing slow-release gel beads as claimed in any one of claims 1 to 3, characterized in that: The following steps are involved: S1, prepare antibacterial guide strip, dissolve chitosan in acetic acid solution, adjust pH, then add epoxy quaternary ammonium salt and dialdehyde polyethylene glycol in sequence under heating and stirring conditions, ultrasonicate and react for a period of time, then add a certain amount of sodium hydroxide solution to obtain a chitosan mixed solution, pour the chitosan mixed solution into a strip mold, let it stand, and after the chitosan mixed solution solidifies, obtain a strip intermediate, dialyze the strip intermediate with deionized water for 24 hours to obtain a composite chitosan gel strip, place the composite chitosan gel strip in a gelatin solution of a certain concentration, then separate the composite chitosan gel strip and place it in a low temperature environment to solidify the gelatin to form a gelatin outer layer to obtain an antibacterial guide strip; S2, preparing sustained-release gel beads, mixing wormwood extract, lithospermum officinale extract, tea polyphenols, xanthan gum and calcium chloride in deionized water, heating at 30-40°C to dissolve, obtaining inner sustained-release bead gel solution, dissolving gelatin and sodium alginate in deionized water under heating conditions, cooling to room temperature, then adding gelatin particles, mixing evenly to obtain mixed gelatin solution, slowly dripping the inner sustained-release bead gel solution into the mixed gelatin solution, reacting and curing to form a composite gelatin protective shell, then filtering and separating, and drying the surface to obtain sustained-release gel beads; S3, bonding a number of antibacterial guide strips to the surface of the non-woven fabric of the guide layer at equal intervals in the width direction of the diaper by means of an adhesive to obtain a composite guide layer, and mixing the slow-release gel beads, the polymer absorbent resin and the fluff pulp to obtain a composite core; S4, compounding the surface layer, the composite guide layer, the composite core body and the bottom layer in sequence to obtain an antibacterial adult diaper.

5. The production process of antibacterial adult diapers containing slow-release gel beads according to claim 4, characterized in that: In step S1, the deacylation degree of the chitosan is 75-80%, the molecular weight of the chitosan is 150,000-170,000 Da, the epoxy quaternary ammonium salt is selected from any one of glycidyltrimethylammonium chloride and hexyldimethylglycidylammonium chloride, the molecular weight of the bisaldehyde polyethylene glycol is 10,000-20,000, and the mass ratio of the chitosan, epoxy quaternary ammonium salt and bisaldehyde polyethylene glycol is 1:0.2:(0.5-1).

6. The production process of antibacterial adult diapers containing slow-release gel beads according to claim 4, characterized in that: In step S1, chitosan is dissolved in 40-50 times the volume of 1% acetic acid solution at 60°C and a stirring speed of 400 rpm, and then a 1M sodium hydroxide solution is used to adjust the pH to 5.5-6.5, and then the temperature is increased to 70-90°C, and epoxy quaternary ammonium salt and dialdehyde polyethylene glycol are added in sequence, ultrasonicated for 1-2h, and then 0.5-2 times the volume of 2% sodium hydroxide solution is added to obtain a chitosan mixed solution.

7. The production process of antibacterial adult diapers containing slow-release gel beads according to claim 4, characterized in that: In step S1, the composite chitosan gel strip has a width of 2-3 mm and a thickness of 1-1.5 mm. The composite chitosan gel strip is placed in a 20% gelatin aqueous solution, and then the composite chitosan gel strip is separated and placed in a low temperature environment of 5°C to solidify the gelatin to form a gelatin outer layer with a thickness of 0.1-0.3 mm.

8. The production process of antibacterial adult diapers containing slow-release gel beads according to claim 4, characterized in that: In step S2, the wormwood extract is wormwood essential oil, and the lithospermum extract is a viscous paste extracted with lithospermum alcohol.

9. The production process of antibacterial adult diapers containing slow-release gel beads according to claim 4, characterized in that: In step S2, 50 parts of gelatin and 10 parts of sodium alginate are dissolved in 100 parts of deionized water at 30° C. under heating conditions, cooled to room temperature, and then 5 parts of gelatin particles with a particle size of 0.05-0.1 mm are added and mixed evenly to obtain a mixed gelatin solution.

10. The production process of antibacterial adult diapers containing slow-release gel beads according to claim 4, characterized in that: In step S2, when the internal sustained-release bead gel solution is slowly dripped into the mixed gelatin solution, the diameter of the spheres when the mixed gelatin solution is dripped is controlled to be 2-3 mm.

Images