Interventional drainage shunt tube with slit valve

Abstract

The invention relates to the technical field of medical instruments, and discloses an interventional drainage shunt tube with a slit valve. The catheter comprises a catheter body of a tubular structure, the catheter body comprises a far-end part provided with an inlet, a near-end part arranged as a blind end and an inner cavity communicating the far-end part and the near-end part, and a slit valve is arranged on the peripheral wall, close to the blind end, of the near-end part. The slit valve is opened through the pressure difference between the ventricular system and the venous system to discharge cerebrospinal fluid from the ventricular system to the venous system, and the distance 10 between the end, close to the blind end, of the slit valve and the blind end in the axial direction meets # imgabs0 #, so that the situation that excessive gas remains in the drainage shunt tube, and consequently the drainage shunt tube is completely blocked and fails is avoided. According to the drainage shunt tube, gas residues in the blind end of the shunt tube can be reduced, and stable drainage of the shunt tube can be ensured, so that the safety and the stability of the drainage shunt tube are improved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical equipment, and in particular to an interventional drainage shunt tube with a slit valve. Background Art

[0002] Hydrocephalus is one of the most common and important neurosurgical conditions affecting children and adults. Hydrocephalus, meaning "water in the brain," refers to the abnormal accumulation of cerebrospinal fluid (CSF) in the brain. Excessive intracranial pressure caused by hydrocephalus can lead to a number of significant symptoms, ranging from headaches to neurological dysfunction, coma, and death. Cerebrospinal fluid is a clear physiological fluid that bathes the entire nervous system, including the brain and spinal cord. CSF is produced by cells of the choroid plexus, which resides within the ventricles of the brain. In normal patients, cells within the arachnoid granulations reabsorb the CSF produced in the choroid plexus. The arachnoid granulations span the surface of the intracranial venous drainage system of the brain and reabsorb CSF present in the subarachnoid space into the venous system. Approximately 450 mL to 500 mL of CSF are produced and reabsorbed daily, enabling a steady-state volume and pressure of approximately 8-16 cm H2O to be produced in the intracranial chambers.

[0003] Hydrocephalus most often occurs due to impaired reabsorption of CSF, but sometimes also due to its overproduction. Disorders in which reabsorption is impaired are called communicating hydrocephalus. Normal pressure hydrocephalus (NPH) is a form of communicating hydrocephalus. Unlike other forms of communicating hydrocephalus, patients with NPH may show little or no increase in intracranial pressure. It is believed that in patients with NPH, the CSF-filled ventricles in the brain enlarge to accommodate the increased volume of CSF in the subarachnoid space.

[0004] Typically, CSF is "shunted" (diverted) using the following types of shunts: A ventriculoperitoneal shunt diverts CSF from the ventricles of the brain to the abdominal cavity. A ventriculo-atrial shunt diverts CSF from the ventricles of the brain to the cavities of the heart. A lumbar-peritoneal shunt diverts CSF from the lower back to the abdominal cavity.

[0005] In recent years, a percutaneous / vascular interventional treatment method for shunt of cerebrospinal fluid has been proposed. The specific treatment method is to deploy a shunt in the patient's ventricles and adjacent veins, such as the cerebellopontine angle cistern and the inferior petrosal sinus. The distal part of the shunt is introduced through the IPS and fixed in the patient's cerebellopontine (CP) angle cistern, which contains cerebrospinal fluid (CSF); the proximal part of the shunt is fixed in or near the patient's jugular vein (JV); CSF flows from the CP angle cistern into the JV through the flow channel of the shunt to maintain a normal pressure difference between the patient's subarachnoid space and venous system.

[0006] The standard treatment for hydrocephalus is to implant a shunt. Although there is no cure for hydrocephalus, shunts can help relieve some of the symptoms of the condition. A shunt drains excess cerebrospinal fluid from the ventricles of the brain and redirects it to another part of the body. This procedure helps the enlarged ventricles return to their normal size and relieves the symptoms of hydrocephalus. Shunts are usually made of silicone and plastic, and all of the components of the shunt are placed under the skin, with no parts outside the body.

[0007] Existing shunts usually include a catheter and a one-way valve, which is used to adjust the amount, flow direction and pressure of cerebrospinal fluid flowing out of the ventricle. The slit valve is an early one-way valve solution for hydrocephalus drainage devices, and is often used in treatment methods such as ventriculoperitoneal shunts. The principle of the slit valve is that when the pressure inside the tube is greater than the pressure outside the tube, the tube wall is deformed by force, the valve on the tube body opens, and the fluid in the tube flows out of the tube; when the pressure inside the tube is less than the pressure outside the tube, the tube wall recovers and the valve gradually closes. The slit valve is set on the side wall of the tube body. There is a blind end at one end of the shunt tube, and there is a blind cavity in the tube. The gas in the blind cavity will be difficult to discharge. The silicone tube used in outdoor drainage methods such as ventriculoperitoneal drainage has a thick wall and a large inner diameter. Before implantation, the shunt tube can be exhausted by pressing and assisted flushing. Even if there is gas remaining at the blind end of the shunt tube after implantation, it will not have a significant impact on the human body, and the residual gas will not affect the shunt function of the slit of the shunt tube.

[0008] However, due to the specific application environment of the drainage scheme, percutaneous / vascular intervention for cerebrospinal effusion shunt requires a small diameter of the tube body to avoid the tube body being too large to block the vein and cause thrombosis, and requires a thin tube wall to match the opening pressure and flow rate requirements of ventricular venous drainage. Therefore, the shunt tube needs to be a thin-walled capillary. For thin-walled capillaries, the surface tension between gas-liquid-tube body has a great influence on the capillary cavity, and the slit valve on the thin-walled capillary is easily damaged. Therefore, it is difficult to discharge the gas in the thin-walled capillary tube by squeezing in the outdoor drainage method, and it is easy to damage the shunt tube and the slit valve; and after the shunt tube is implanted in the blood vessel, the coagulation components in the blood flow or diffuse in reverse and react with the gas in the blind cavity, which is easy to form thrombus emboli and block the valve, or even form gas embolism. For example, when the pressure outside the tube is greater than or equal to the pressure inside the tube and the valve is not closed in time, the blood reacts with the gas in the blind cavity to form an embolus. In addition, before surgery, the temperature of the shunt in the operating room is usually lower than that of the human body, such as 25 degrees Celsius; after the shunt is implanted in the human body, the temperature of the environment in which the shunt is located increases relative to the temperature of the operating room, and the unexpelled gas expands in the lumen of the shunt, increasing the gas pressure. In addition, the pressure difference between the posterior cerebral cistern and the vein after implantation is not sufficient to discharge the gas, thereby affecting the drainage effect of the shunt, and even closing the valve due to the elastic force of the tube body, resulting in shunt failure.

[0009] Therefore, when using vascular interventional drainage to treat hydrocephalus, reducing the residual gas in the slit valve of the shunt and ensuring stable drainage of the shunt is an urgent problem to be solved. Summary of the invention

[0010] In order to solve the above technical problems, the present invention provides an interventional drainage shunt tube with a slit valve, which is deployed in the patient's ventricular system and venous system to discharge cerebrospinal fluid in the patient's ventricular system into the venous system, thereby improving the stability and safety of the interventional drainage shunt tube.

[0011] The present invention is implemented by the following technical solution: a tube body including a tubular structure, the tube body including a distal portion provided with a cerebrospinal fluid inlet, a proximal portion provided as a blind end, and an inner cavity connecting the distal portion and the proximal portion, a slit valve is provided on the peripheral wall of the proximal portion near the blind end, the slit valve is opened by the pressure difference between the ventricular system and the venous system to discharge cerebrospinal fluid from the ventricular system to the venous system, the slit valve extends in the axial direction of the tube body to form an axial length L1 that is longer than that in the radial direction, and a distance l0 between one end of the slit valve close to the blind end and the blind end in the axial direction satisfies: , where T1 is the temperature of the shunt tube during hydration and exhaust, P2 is the relative pressure of cerebrospinal fluid in the ventricle, P1 is the air pressure, and T2 is the human body temperature. In this way, it is avoided that too much gas remains between the slit valve and the blind end of the drainage shunt tube body, which eventually leads to complete blockage and failure of the drainage shunt tube.

[0012] As a further improvement of the above scheme, the slit valve includes a first valve slit, which extends in the axial direction of the tube body to form an axial length L1 that is longer than the radial direction, and the axial length L1 of the first valve slit is less than or equal to 8 mm, and the outer diameter of the tube body is less than or equal to 1 mm, and the inner diameter is less than or equal to 0.5 mm.

[0013] As a further improvement of the above solution, the first valve slit is a first slit, the first slit is parallel to the horizontal axis of the tube body, the length of the first slit is 4-8 mm, and the distance between the side of the first slit close to the blind end and the blind end is 0 mm.

[0014] As a further improvement of the above scheme, the slit valve also includes a second valve slit of a different shape from the first valve slit, the first valve slit and the second valve slit have different lengths, shapes and setting positions, the opening flow of the first valve slit is greater than that of the second valve slit, and the distance between the end of the first valve slit close to the blind end and the blind end in the axial direction is l0, and l0 satisfies ; Alternatively, the slit valve further comprises a second valve slit of the same shape as the first valve slit, the second valve slit is closer to the blind end relative to the first valve slit, and the distance between the end of the first valve slit closer to the blind end and the blind end in the axial direction is l0, and l0 satisfies .

[0015] In this way, by setting the first valve slit, the second valve slit and the distance from the blind end, the interventional drainage shunt tube can be matched with different opening pressures, while preventing the slit valve from failing due to excessive gas residue.

[0016] As a further improvement of the above scheme, the first valve slit is a second slit away from the blind end, the second slit is parallel to the transverse axis of the tube body or inclined to the transverse axis of the tube body, and the second valve slit is a first sub-slit close to the blind end, and the axial length of the first sub-slit is smaller than the second slit, so that when the pressure in the inner cavity of the tube body is lower than the pressure on the outer surface, the tube wall is compressed to allow the second slit to close.

[0017] As a further improvement of the above scheme, a first valve slit and a second valve slit are provided on the tube body, wherein the first valve slit is a third slit close to the blind end and parallel to the horizontal axis of the tube body, and the second valve slit is a second sub-slit away from the blind end, and the axial length of the second sub-slit is smaller than the third slit, so that when the intracranial pressure is low, only the third slit is opened, and when the opening pressure of the second sub-slit is reached, the second sub-slit and the third slit can be opened at the same time.

[0018] As a further improvement of the above scheme, a first valve slit and a second valve slit are provided on the tube body, the first valve slit is a fourth slit parallel to the horizontal axis of the tube body and located close to the blind end position, and the second valve slit is a plurality of small valve openings away from the blind end position, and the axial length of a single small valve opening is smaller than the first valve slit.

[0019] As a further improvement of the above solution, an adjustment structure is provided at the end of the first valve slit, and the adjustment structure is a slit or a hole, which can further prevent the first valve slit from retaining gas and causing the drainage shunt tube to fail; And / or, an adjustment structure is provided on the same circumferential tube body section of the first valve slit, and the adjustment structure penetrates or does not penetrate the side wall of the tube body, which can further reduce the opening pressure and flow resistance of the slit valve and ensure the stability of the opening of the slit valve on the interventional drainage shunt tube.

[0020] As a further improvement of the above solution, the proximal end of the tube body is filled with a filler to form a blind end, and the filler includes one or a combination of silicone glue, metal, and UV light-curing glue; As a further improvement of the above solution, the tube body includes silicone and metal materials of different structures, so as to change the surface tension between solid-liquid, solid-gas, and gas-liquid, as well as the interaction with the tube body and the opening pressure of the slit valve.

[0021] Compared with the prior art, the present invention has the following beneficial effects: By setting the position of the slit valve on the drainage shunt tube, the distance l0 between the slit valve and the blind end of the drainage shunt tube body is set to meet , so as to avoid excessive gas remaining between the slit valve and the blind end of the drainage shunt tube body, thereby preventing the coagulation components in the blood from flowing back or diffusing and interacting with the gas retained in the shunt tube to form a thrombus embolus to block the slit valve orifice, causing the drainage shunt tube to be completely blocked and fail.

[0022] The spacing l0 between the slit valve and the blind end of the drainage shunt tube is set to 0 mm, so that there will be no retention cavity between the slit valve and the blind end of the drainage shunt tube, so that when the gas is transported into the drainage shunt tube, it is less likely to be retained in the drainage shunt tube body, and can be directly discharged smoothly through the slit valve, thereby preventing the coagulation components in the blood from reacting with the gas retained in the blind end when flowing backward or diffusing, which can easily form thrombus emboli; The body of the drainage shunt tube is a combination of metal and silicone, and the metal and silicone have different combinations. Different combinations can change the surface tension between solid-liquid, solid-gas, and gas-liquid, as well as the interaction with the tube body and the opening pressure of the slit valve, thereby improving the gas discharge effect; The slit valve includes a first valve slit and a second valve slit, and the first valve slit has different lengths, shapes and setting positions, while the second valve slit has different forms. The combination of the two different forms makes the slit valve have different opening pressures, which can not only avoid backflow of the slit valve, but also ensure the stability of the slit valve, avoid the situation of too fast or too slow flow rate, thereby ensuring that the drainage shunt tube can drain stably. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 A schematic diagram of a treatment method for percutaneous / vascular intervention to divert cerebral fluid; Figure 2 The overall structure of the interventional drainage shunt tube with a slit valve of the present invention is shown; Figure 3 It is a planar cross-sectional illustration of an interventional drainage shunt tube with a slit valve according to the present invention; Figure 4 It is a diagram showing a first embodiment of an interventional drainage shunt tube with a slit valve according to the present invention; Figure 5A diagram showing a second embodiment of an interventional drainage shunt tube with a slit valve according to the present invention; Figure 6 A diagram showing a third embodiment of an interventional drainage shunt tube with a slit valve according to the present invention; Figure 7 FIG. 4 is a diagram showing a fourth embodiment of an interventional drainage shunt tube with a slit valve according to the present invention; Figure 8 It is a display diagram of different sections of the valve slit of the present invention; Fig. 9 This is a diagram showing the force expansion of the pipe body in the present invention; Fig.10 It is a diagram showing different material structure ratios of the pipe body in the present invention; Fig.11 This is an expanded display diagram of the interventional drainage shunt tube with an adjustment structure and a slit valve in the present invention; Fig.12 This is a diagram showing an interventional drainage shunt tube with an adjustment structure and a slit valve in the present invention.

[0024] Description of main symbols: 1. Tube body; 101. Silicone; 102. Metal material; 2. Silicone glue; 3. Developing ring; 4. First valve seam; 401. First seam opening; 402. Second seam opening; 403. Third seam opening; 404. Fourth seam opening; 5. Second valve seam; 502. First secondary seam opening; 503. Second secondary seam opening; 504. Small valve opening; 6. Adjustment structure; 7. Adjustment structure; 8. Thin-walled metal ring; 9. Blind end. DETAILED DESCRIPTION

[0025] The present invention is further described below in conjunction with the accompanying drawings and specific implementation methods.

[0026] Please combine Figure 1-Figure 12 The present invention discloses an interventional drainage shunt tube with a slit valve, which is used to be deployed in the ventricular system and venous system of a patient to discharge cerebrospinal fluid in the ventricular system of the patient to the venous system, and comprises a tube body 1 of a tubular structure, wherein the tube body 1 comprises a distal portion provided with a cerebrospinal fluid inlet, a proximal portion provided with a blind end 9, and an inner cavity connecting the distal portion and the proximal portion, a slit valve is provided on the peripheral wall of the proximal portion near the blind end 9, the slit valve is opened by the pressure difference between the ventricular system and the venous system to discharge cerebrospinal fluid from the ventricular system to the venous system, the slit valve extends in the axial direction of the tube body 1 to form an axial length L1 that is longer than that in the radial direction, and a distance l0 between the end of the slit valve near the blind end 9 and the blind end 9 in the axial direction satisfies , where T1 is the temperature of the shunt tube during hydration and exhaust, L1 is the axial length of the slit valve, P2 is the relative pressure of cerebrospinal fluid in the ventricle, P1 is the air pressure, and T2 is the human body temperature, so as to avoid excessive gas remaining between the slit valve and the blind end 9 of the drainage shunt tube body, thereby preventing the coagulation components in the blood from flowing back or diffusing and interacting with the gas retained in the shunt tube to form a thrombus embolus to block the slit valve port, resulting in complete blockage and failure of the drainage shunt tube.

[0027] The slit valve includes a first valve slit 4, which extends in the axial direction of the tube body 1 to form an axial length L1 that is longer than the radial direction, and the axial length L1 of the first valve slit 4 is less than or equal to 8 mm, and the tube body 1 is a capillary tube with an outer diameter less than or equal to 1 mm and an inner diameter less than or equal to 0.5 mm. Preferably, the axial length L1 of the first valve slit 4 is less than or equal to 6.5 mm.

[0028] The slit valve includes a first valve slit 4 and a second valve slit 5 of a different form from the first valve slit 4. The first valve slit 4 has different lengths, shapes and setting positions, so that the slit valve can have different opening pressures and different exhaust effects. The opening flow rate of the first valve slit 4 is greater than that of the second valve slit 5. The distance between one end of the first valve slit 4 close to the blind end 9 and the blind end 9 in the axial direction is l0, and l0 satisfies: , where T1 is the temperature of the shunt tube during hydration exhaust, L1 is the axial length of the slit valve, P2 is the relative pressure of cerebrospinal fluid in the ventricle, P1 is the air pressure, and T2 is the human body temperature.

[0029] Alternatively, the slit valve includes a first valve slit 4, and a second valve slit 5 of the same shape as the first valve slit 4, the second valve slit 5 is closer to the blind end 9 relative to the first valve slit 4, and the distance between the end of the first valve slit 4 closer to the blind end 9 and the blind end 9 in the axial direction is l0, and l0 satisfies , where T1 is the temperature of the shunt tube during hydration exhaust, L1 is the axial length of the slit valve, P2 is the relative pressure of cerebrospinal fluid in the ventricle, P1 is the air pressure, and T2 is the human body temperature.

[0030] The slit valve is a one-way valve, which is defined as a reverse flow rate of less than 5 ml / hour within a pressure range of 400 mmH2O (due to defects in the processing of thin-walled capillaries, it is impossible to completely guarantee that there is no reverse flow. As long as the reverse flow rate is less than a specific value within the working range, it is considered to meet the one-way function). When the pressure in the inner cavity of the tube body 1 is less than the pressure on the outer surface, the tube wall is compressed and the first valve slit 4 is closed, so that external liquid cannot enter the inner cavity. When the pressure in the inner cavity of the tube body 1 is greater than the pressure on the outer surface, the tube wall expands, the outer diameter increases, and the first valve slit 4 opens slightly. The first valve slit 4 and the second valve slit 5 are not connected, which can improve the strength of the tube body 1 and thereby reduce the damage to the strength of the tube body 1 caused by the slit valve.

[0031] Specifically, the outer diameter of the tube body 1 is 0.5-0.7 mm, and the inner diameter is 0.2-0.3 mm.

[0032] refer to Figure 8 The side wall structure of the first valve slit 4 can be parallel to or inclined with the axial cross section of the tube body 1 .

[0033] There is at least one first valve slit 4 in the slit valve with the maximum flow rate within the pressure range of 400 mm H2O, and the maximum axial distance between the blind end 9 and the first valve slit 4 is l0. , where T1 is the temperature of the shunt pipe during hydration exhaust, L1 is the axial length of the first valve slit 4, is the relative pressure of cerebrospinal fluid in the ventricles, is the air pressure, T2 is the human body temperature.

[0034] The blind end 9 is composed of silicone glue 2 and a developing ring 3, including but not limited to silicone glue 2, metal, UV light curing glue, etc. and their combinations.

[0035] like Fig.10 As shown, the tube body 1 is made of elastic material, and is composed of silicone 101 of different structures and metal material 102. The silicone 101 can also be replaced by similar materials such as TPU, wherein the metal material 102 includes but is not limited to stainless steel, nickel-titanium alloy, and titanium alloy. The tube body 1 can be configured so that the inner wall tube is metal material 102 and the outer wall tube is silicone 101; or the metal material 102 is in the middle of the silicone tube body; the metal material 102 can also be arranged on the outside of the silicone tube body; and the combination of different structures can change the surface tension between solid-liquid, solid-gas, and gas-liquid, as well as the interaction with the tube body 1 and the opening pressure of the slit valve, thereby improving the gas discharge effect.

[0036] The first valve slit 4 is a slit formed directly on the tube body 1 and penetrating the tube wall; it can also be a slit valve element fixed to the tube body 1, see Fig.11 .

[0037] See also Fig.11 A thin-walled metal ring 8 is arranged around the first valve slit 4 to play a developing role.

[0038] The inner wall and surface of the tube body 1 are provided with a hydrophilic coating, especially at the entrance of the tube body 1 and adjacent positions. The hydrophilic coating may be a phosphorylcholine coating to improve the hydrophilicity and hydrophobicity of the surface of the tube body 1, thereby improving the exhaust conditions.

[0039] like Fig.11 The end of the first valve slit 4 is provided with an adjustment structure 6, which is a slit or a hole. The arrangement of the adjustment structure 6 can further prevent the first valve slit 4 from retaining gas and causing the drainage shunt tube to fail. Fig.11(a) to (c), the slit adjustment structure extends in the direction of the first valve slit 4 at an angle; see Fig.11 (d) The hole adjustment structure is set to a size larger than the width of the first valve slit 4.

[0040] like Fig.12 An adjustment structure 7 is provided on the same circumferential tube body section of the first valve slit 4. The adjustment structure 7 penetrates or does not penetrate the side wall of the tube body 1. The axial length of the adjustment structure 7 is smaller than the first valve slit 4. The adjustment structure 7 is a penetrating slit or a non-penetrating slit or a non-penetrating hole, which can further reduce the opening pressure and flow resistance of the slit valve and ensure the stability of the opening of the slit valve on the interventional drainage shunt tube.

[0041] The regulating structure 6 and the adjusting structure 7 may exist separately and cooperate with the first valve slit 4, or may exist simultaneously.

[0042] In the first embodiment of the present invention, Figure 4 As shown, a first valve slit 4 is separately provided on the tube body 1, and the first valve slit 4 is a first slit opening 401. The first slit opening 401 is parallel to the horizontal axis of the tube body 1, and the axial length (L1) of the first slit opening 401 is 4-8 mm. The axial length (L1) of the first slit opening 401 is preferably 4-6 mm, and the distance (l0) between the first slit opening 401 and the blind end 9 is 0 mm, so as to avoid residual gas in the space between the first slit opening 401 and the blind end 9.

[0043] To avoid complete blockage, In order to prevent the influence of the gas at the blind end 9, the distance between the blind end 9 and the first slit 401 is 0 mm.

[0044] In the second embodiment of the present invention, Figure 5 As shown, the pipe body 1 is provided with a first valve slit 4 and a second valve slit 5, the first valve slit 4 is a second slit opening 402 away from the blind end 9, the second slit opening 402 is parallel to the horizontal axis of the pipe body 1 or inclined to the horizontal axis of the pipe body 1, the second valve slit 5 is a first sub-slit opening 502 close to the blind end 9, the pipe body 1 is provided with two slit openings, the second slit opening 402 and the first sub-slit opening 502, the axial length of the first sub-slit opening 502 is smaller than the second slit opening 402, and under normal circumstances, the flow rate of the second slit opening 402 is the maximum , the flow rate of the first slit 502 is small or in a closed state, the inclination angle of the second slit 402 with the horizontal axis of the tube body 1 is less than 45° when the second slit 402 is in an inclined state, the length L1 of the second slit 402 is 4.5 mm, the relative pressure of the cerebrospinal fluid in the ventricle is 103.3 kPa, the hydration temperature T1 before implantation is 20°C, the air pressure before implantation is 101.3 kPa, and the human body temperature T2 is 37°C. At this time, the distance l0 between the second slit 402 and the blind end 9 must meet mm.

[0045] In the third embodiment of the present invention, Figure 6 As shown, a first valve slit 4 and a second valve slit 5 are provided on the tube body 1. The first valve slit 4 is a third slit 403 close to the blind end 9 and parallel to the horizontal axis of the tube body 1, and the second valve slit 5 is a second sub-slit 503 away from the blind end 9. In this embodiment, the axial length of the second sub-slit 503 is smaller than the axial length of the third slit 403, the flow rate of the third slit 403 is greater than the second sub-slit 503, and the opening pressure of the second sub-slit 503 is greater than the third slit 403. When the intracranial pressure is low, only the third slit 403 is opened, and when the opening pressure of the second sub-slit 503 is reached, the second sub-slit 503 and the third slit 403 are opened at the same time, so as to accelerate the discharge of intracranial water accumulation, and also solve the problem of too fast flow rate when the intracranial pressure is low, so as to achieve multi-stage flow rate control under different intracranial pressure conditions.

[0046] In the fourth embodiment of the present invention, Figure 7 As shown, a first valve slit 4 and a second valve slit 5 are provided on the tube body 1. The first valve slit 4 is a fourth slit 404 parallel to the horizontal axis of the tube body 1 and located near the blind end 9. The second valve slit 5 is a plurality of small valve openings 504 away from the blind end 9. The second valve slit 5 can be a plurality of small valve openings 504 of different lengths, which are not connected to each other. The plurality of small valve openings 504 can be on the same horizontal axis, or at different heights and positions. The axial length of a single small valve opening 504 is smaller than the first valve slit 4.

[0047] The above-mentioned embodiments are only preferred embodiments of the present invention and cannot be used to limit the scope of protection of the present invention. Any non-substantial changes and substitutions made by technicians in this field on the basis of the present invention shall fall within the scope of protection required by the present invention.

Claims

1. An interventional drainage shunt with a slit valve, used for being deployed in a patient's ventricular system and venous system to discharge cerebrospinal fluid in the patient's ventricular system into the venous system, characterized in that: A tube body (1) comprising a tubular structure, the tube body (1) comprising a distal portion provided with an inlet, a proximal portion provided as a blind end (9), and an inner cavity connecting the distal portion and the proximal portion, a slit valve being provided on a peripheral wall of the proximal portion near the blind end (9), the slit valve being opened by a pressure difference between the ventricular system and the venous system to discharge cerebrospinal fluid from the ventricular system to the venous system; The slit valve extends in the axial direction of the tube body (1) to form an axial length L1 that is longer than that in the radial direction, and the distance between the end of the slit valve close to the blind end (9) and the blind end (9) in the axial direction is l0 to satisfy , where T1 is the temperature of the shunt tube during hydration exhaust, P2 is the relative pressure of cerebrospinal fluid in the ventricles, P1 is the air pressure, and T2 is the human body temperature.

2. The interventional drainage shunt tube with a slit valve according to claim 1, characterized in that: The slit valve comprises a first valve slit (4), the first valve slit (4) extending in the axial direction of the tube body (1) to form an axial length L1 that is longer than the radial direction, the axial length L1 of the first valve slit (4) being less than or equal to 8 mm, and the outer diameter of the tube body (1) being less than or equal to 1 mm and the inner diameter being less than or equal to 0.5 mm.

3. The interventional drainage shunt tube with a slit valve according to claim 2, characterized in that: The first valve slit (4) is a first slit opening (401), the first slit opening (401) is parallel to the horizontal axis of the tube body (1), the length of the first slit opening (401) is 4-8 mm, and the distance between the side of the first slit opening (401) close to the blind end (9) and the blind end (9) is 0 mm.

4. The interventional drainage shunt tube with a slit valve according to claim 2, characterized in that: The slit valve further comprises a second valve slit (5) of a different shape from the first valve slit (4), the first valve slit (4) and the second valve slit (5) having different lengths, shapes and arrangement positions, the opening flow rate of the first valve slit (4) being greater than that of the second valve slit (5), and the distance between an end of the first valve slit (4) close to the blind end (9) and the blind end (9) in the axial direction is l0, and l0 satisfies ; Alternatively, the slit valve further comprises a second valve slit (5) of the same shape as the first valve slit (4), the second valve slit (5) being closer to the blind end (9) relative to the first valve slit (4), and the distance between an end of the first valve slit (4) closer to the blind end (9) and the blind end (9) in the axial direction is l0, and l0 satisfies .

5. The interventional drainage shunt tube with a slit valve according to claim 4, characterized in that: The first valve slit (4) is a second slit (402) away from the blind end (9), the second slit (402) is parallel to the transverse axis of the tube body (1) or inclined to the transverse axis of the tube body (1), and the second valve slit (5) is a first secondary slit (502) close to the blind end (9), the axial length of the first secondary slit (502) is smaller than the second slit (402), so that when the pressure in the inner cavity of the tube body (1) is lower than the pressure on the outer surface, the tube wall is compressed to allow the second slit (402) to close.

6. The interventional drainage shunt tube with a slit valve according to claim 4, characterized in that: The first valve slit (4) is a third slit (403) close to the blind end (9) and parallel to the horizontal axis of the tube body (1), and the second valve slit (5) is a second secondary slit (503) away from the blind end (9). The axial length of the second secondary slit (503) is smaller than that of the third slit (403), so that when the intracranial pressure is low, only the third slit (403) is opened, and when the opening pressure of the second secondary slit (503) is reached, the second secondary slit (503) and the third slit (403) can be opened simultaneously.

7. The interventional drainage shunt tube with a slit valve according to claim 4, characterized in that: The first valve slit (4) is a fourth slit (404) parallel to the transverse axis of the tube body (1) and located close to the blind end (9), and the second valve slit (5) is a plurality of small valve openings (504) located away from the blind end (9), and the axial length of a single small valve opening (504) is smaller than that of the first valve slit (4).

8. The interventional drainage shunt tube with a slit valve according to claim 2, characterized in that: An adjustment structure (6) is provided at the end of the first valve slit (4), and the adjustment structure (6) is a slit or a hole; And / or, an adjustment structure (7) is provided on the same circumferential tube body section of the first valve slit (4), and the adjustment structure (7) penetrates or does not penetrate the side wall of the tube body (1).

9. The interventional drainage shunt tube with a slit valve according to claim 1, characterized in that: The proximal end portion of the tube body (1) is filled with a filler to form a blind end (9), wherein the filler comprises one of silicone glue (2), metal, and UV light-curing glue, or a combination thereof.

10. The interventional drainage shunt tube with a slit valve according to claim 1, characterized in that: The tube body (1) comprises silica gel (101) and metal material (102) of different structures, thereby being able to change the surface tension between solid-liquid, solid-gas, and gas-liquid, as well as the interaction with the tube body (1) and the opening pressure of the slit valve.

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