Granulation equipment for producing solid granules

Abstract

The utility model belongs to the technical field of solid granule production, and particularly relates to granulation equipment for solid granule production, which comprises a granulation box, a stirring box and a hydraulic cylinder are fixedly mounted at the top of the granulation box, a plurality of discharge pipes are fixedly mounted at the top of the stirring box, valves are rotatably mounted in the discharge pipes, and the hydraulic cylinder is connected with the stirring box. A charging box is fixedly mounted at the top end of the discharging pipe, and scale marks can be arranged on one side of the charging box; the rotating rod is rotationally mounted at the bottom of an inner cavity of the stirring box, a plurality of stirring rods are fixedly mounted on the peripheral side of the rotating rod, and a scraper is fixedly mounted on the rotating rod and located at the bottom of the inner cavity of the stirring box; according to the utility model, various powdery medicaments entering the inner cavity of the stirring box can be accurately controlled, and a liquid adhesive does not need to be added in the granulating process, so that the subsequent drying links and cost are reduced, and meanwhile, the change of medicament components possibly caused by drying in wet granulation is also avoided; the process is relatively simple, and the efficiency is high.

Description

Technical Field

[0001] The utility model belongs to the technical field of solid granule production, in particular to a granulating device used for solid granule production. Background Art

[0002] Granules are a solid dosage form obtained by mixing the original drug with carriers, adhesives, dispersants, wetting agents, stabilizers and other auxiliary agents.

[0003] Common solid granule granulation equipment cannot accurately and quantitatively add various drugs when in use, resulting in different medicinal properties of the produced solid granules. In addition, solid granules are generally produced by wet granulation, which requires the addition of liquid binders, resulting in the need for subsequent drying, which can easily cause changes in the composition of the drug. In view of this, we propose a granulation equipment for the production of solid granules. Utility Model Content

[0004] The purpose of the utility model is to provide a granulation device for producing solid granules to solve the problems raised in the above background technology.

[0005] In view of this, the utility model provides a granulation device for producing solid granules, comprising:

[0006] A granulation box, a mixing box and a hydraulic cylinder are fixedly installed on the top of the granulation box, a plurality of discharge pipes are fixedly installed on the top of the mixing box, a valve is rotatably installed in the discharge pipe, a charging box is fixedly installed on the top of the discharge pipe, and a scale line may be provided on one side of the charging box;

[0007] A rotating rod, the rotating rod is rotatably mounted on the bottom of the inner cavity of the mixing box, a plurality of stirring rods are fixedly mounted on the circumference of the rotating rod, and a scraper is fixedly mounted on the rotating rod and located at the bottom of the inner cavity of the mixing box;

[0008] A granulation chamber, wherein the granulation chamber is opened in a granulation box, wherein an extrusion plate, a pull plate and two crushing rollers are sequentially arranged in the granulation chamber from top to bottom, a connecting pipe is fixedly installed between one side of the granulation box and the bottom of the mixing box, and the output end of the hydraulic cylinder passes through the top of the granulation box and is fixed to the extrusion plate;

[0009] A power assembly, which is located at the bottom of the mixing box and is used to drive the rotating rod to rotate and the two crushing rollers to rotate towards each other;

[0010] A sealing component is located in the mixing box and is used to seal the top end of the connecting pipe.

[0011] In the technical solution, different powdered medicines can be put into several charging boxes from the feeding ports on the tops of several charging boxes respectively through the charging boxes provided, and the personnel can observe the scale lines on the charging boxes to ensure that the amount of powdered medicines in the charging boxes can be accurately controlled. Then the personnel can open several valves respectively, and the powdered medicines in the several charging boxes will respectively enter the inner cavity of the mixing box through several discharge pipes, ensuring that the personnel can accurately control the various powdered medicines entering the inner cavity of the mixing box;

[0012] The power assembly is driven by the power assembly, which will drive the rotating rod to rotate and the two crushing rollers to rotate in the opposite direction. The rotation of the rotating rod will drive a number of stirring rods and scrapers to rotate in the inner cavity of the stirring box. The rotation of the several stirring rods can fully mix the various powdered medicines in the inner cavity of the stirring box. When the various powdered medicines in the stirring box are fully mixed, the top of the connecting pipe can be opened through the sealing assembly, and then the mixed powdered medicines in the inner cavity of the stirring box will flow into the connecting pipe. At the same time, the rotation of the scraper can scrape all the mixed powdered medicines in the inner cavity of the stirring box into the connecting pipe, and then the medicines in the connecting pipe The medicine will enter the granulation chamber and fall to the top of the pull-out plate, and then the hydraulic cylinder will be started. The output shaft of the hydraulic cylinder will drive the extrusion plate to move downward. The downward movement of the extrusion plate will squeeze the medicine and squeeze the powdered medicine into a cake shape. Then the personnel can pull the pull-out plate out of the granulation chamber. At this time, the medicine cake on the pull-out plate will fall to the two crushing rollers. Under the opposite rotation and crushing of the two crushing rollers, the cake-like medicine can be broken into granules, ensuring that no liquid adhesive is added during the granulation process, reducing the subsequent drying links and costs, and also avoiding the changes in drug components that may be caused by drying in wet granulation. The process is relatively simple and efficient.

[0013] In the above technical solution, further, the power assembly includes:

[0014] A double-shaft motor, the double-shaft motor is fixedly installed at the bottom of the mixing box and is located on one side of the connecting tube, one of the output ends of the double-shaft motor passes through the bottom of the mixing box and is coaxially connected to the rotating rod, a fixing plate is fixedly installed on one side of the granulation box and located below the connecting tube, the other output end of the double-shaft motor passes through the fixing plate and is fixedly installed with bevel gear 2, one side of the bevel gear 2 is meshed with bevel gear 1, one end of the bevel gear 1 is fixedly installed with a round rod, and one end of the round rod passes through one side of the granulation box and is coaxially connected to one of the crushing rollers, one end of the two crushing rollers passes through one side of the charging box and is fixedly installed with a first gear, and the two first gears are meshed with each other.

[0015] In the present technical scheme, the dual-axis motor is started, and the two output shafts of the dual-axis motor respectively drive the rotating rod and the bevel gear 2 to rotate. The rotation of the rotating rod will drive a number of stirring rods and scrapers to rotate in the inner cavity of the mixing box. At the same time, under the action of meshing, the rotation of the bevel gear 2 will drive the bevel gear 1 to rotate, and the rotation of the bevel gear 1 will drive the round rod to rotate. The rotation of the round rod will drive one of the crushing rollers to rotate, and the rotation of one of the crushing rollers will drive one of the first gears to rotate. Under the action of meshing, the rotation of one of the first gears will drive the other first gear to rotate, and the rotation of the other first gear will drive the other crushing roller to rotate, ensuring that the two crushing rollers can rotate in opposite directions. The rotation of a number of stirring rods can fully mix the various powdered medicines in the inner cavity of the mixing box.

[0016] In the above technical solution, further, one of the output shafts of the dual-axis motor is rotatably connected to the mixing box, the other output shaft of the dual-axis motor is rotatably connected to the fixed plate, one end of the round rod is rotatably connected to the granulation box, and one end of the crushing roller is rotatably connected to the granulation box.

[0017] In this technical solution, it is ensured that one of the output shafts of the dual-axis motor can rotate normally in the mixing box, that the other output shaft of the dual-axis motor can rotate normally in the fixed plate, that one end of the round rod can rotate normally in the granulation box, and that one end of the crushing roller can rotate normally in the granulation box.

[0018] In the above technical solution, further, the sealing assembly includes:

[0019] A sliding groove is opened in the mixing box and is located at the top of the connecting pipe. A sealing plate is slidably installed in the sliding groove. The sealing plate is located directly above the connecting pipe. A pull rod is fixedly installed on the other side of the sealing plate and located in the sliding groove. One end of the pull rod passes through one side of the sliding groove and extends to the outside.

[0020] In this technical solution, a person can pull the pull rod with force, and the pull rod will drive the sealing plate to move in the sliding groove until the sealing plate opens the top of the connecting pipe, ensuring that the mixed medicine in the inner cavity of the mixing box will flow into the connecting pipe.

[0021] In the above technical solution, further, the pull rod is slidably connected to the sliding groove and the mixing box.

[0022] In this technical solution, it is ensured that the pull rod can slide normally in the sliding groove and the mixing box.

[0023] In the above technical solution, further, a collecting box is installed in the granulation box and below the two crushing rollers, the pulling plate is plugged into the granulation chamber, the extrusion plate is slidably connected to the granulation chamber, and the crushing roller is rotatably connected to the granulation chamber.

[0024] In this technical solution, the cake-like medicine can be broken into granules by the opposite rotation of the two crushing rollers. Finally, the granular medicine will fall into the collection box, ensuring that it is convenient for personnel to collect it, ensuring that the extrusion plate can be inserted into the granulation chamber, ensuring that the extrusion plate can slide normally in the granulation chamber, and ensuring that the crushing rollers can rotate normally in the granulation chamber.

[0025] In the above technical solution, further, the two ends of the connecting pipe are respectively connected to the granulation chamber and the inner cavity of the mixing box, and the two ends of the discharge pipe are respectively connected to the inner cavity of the charging box and the inner cavity of the mixing box.

[0026] In this technical solution, it is ensured that the medicine in the inner cavity of the mixing box can enter the granulation cavity through the connecting pipe, and it is ensured that the medicine in the charging box can enter the inner cavity of the mixing box through the discharge pipe.

[0027] In the above technical solution, further, the bottom end of the connecting pipe is located between the extrusion plate and the pulling plate, and the output shaft of the hydraulic cylinder is slidably connected to the granulation box.

[0028] In this technical solution, the structural stability of the connecting pipe is ensured, and the output shaft of the hydraulic cylinder is ensured to be able to slide normally in the granulation box.

[0029] The beneficial effects of the utility model are:

[0030] 1. The granulating equipment for the production of solid granules can put different powdered medicines into several charging boxes from the feeding ports on the tops of several charging boxes through the provided charging boxes. At the same time, the personnel can observe the scale lines on the charging boxes to ensure that the amount of powdered medicines in the charging boxes can be accurately controlled. Then the personnel can open several valves respectively. At this time, the powdered medicines in the several charging boxes will enter the inner cavity of the mixing box through several discharge pipes respectively, ensuring that the personnel can accurately control the various powdered medicines entering the inner cavity of the mixing box.

[0031] 2. The granulating equipment for the production of solid granules is driven by a power assembly, which drives the rotating rod to rotate and the two crushing rollers to rotate in the opposite direction. The rotation of the rotating rod drives a plurality of stirring rods and scrapers to rotate in the inner cavity of the stirring box. The rotation of the plurality of stirring rods can fully mix the various powdered medicines in the inner cavity of the stirring box. When the various powdered medicines in the stirring box are fully mixed, the top of the connecting pipe can be opened by the sealing assembly, and then the mixed powdered medicines in the inner cavity of the stirring box will flow into the connecting pipe. At the same time, the rotation of the scraper can scrape all the mixed powdered medicines in the inner cavity of the stirring box into the connecting pipe. , then the medicine in the connecting tube will enter the granulation chamber and fall to the top of the pull-out plate, and then the hydraulic cylinder will be started. The output shaft of the hydraulic cylinder will drive the extrusion plate to move downward. The downward movement of the extrusion plate will squeeze the medicine and squeeze the powdered medicine into a cake shape. Then the personnel can pull the pull-out plate out of the granulation chamber. At this time, the medicine cake on the pull-out plate will fall onto the two crushing rollers. Under the opposite rotation and crushing of the two crushing rollers, the cake-like medicine can be broken into granules, ensuring that no liquid adhesive is added during the granulation process, reducing the subsequent drying links and costs, and also avoiding the changes in drug components that may be caused by drying in wet granulation. The process is relatively simple and the efficiency is high. BRIEF DESCRIPTION OF THE DRAWINGS

[0032] Figure 1 This is one of the overall structural diagrams of the utility model;

[0033] Figure 2 This is the second schematic diagram of the overall structure of the utility model;

[0034] Figure 3 It is a schematic diagram of the detailed internal structure of the granulation box and the mixing box in the utility model;

[0035] Figure 4 For this utility model Figure 3 The enlarged structural diagram at A in the middle;

[0036] Figure 5 It is a schematic diagram of the cross-sectional structure of the mixing box in the utility model;

[0037] Figure 6 This is one of the schematic diagrams of the mixing box area structure in the utility model;

[0038] Figure 7 This is the second schematic diagram of the mixing box area structure in the utility model.

[0039] The symbols in the figure are:

[0040] 1. Granulation box; 2. Mixing box; 3. Discharge pipe; 4. Loading box; 5. Scale line; 6. Valve; 7. Rotating rod; 8. Mixing rod; 9. Scraper; 11. Sliding groove; 12. Sealing plate; 13. Pull rod; 14. Granulation chamber; 15. Pull plate; 16. Extrusion plate; 17. Hydraulic cylinder; 18. Crushing roller; 19. First gear; 20. Double-axis motor; 21. Round rod; 22. Bevel gear one; 23. Bevel gear two; 24. Fixed plate; 25. Collecting box; 26. Connecting pipe. DETAILED DESCRIPTION

[0041] The following will be combined with the drawings in the embodiments of the present application to clearly describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are part of the embodiments of the present application, rather than all the embodiments. All other embodiments obtained by ordinary technicians in this field based on the embodiments in the present application belong to the scope of protection of this application.

[0042] In the description of the present application, it should be noted that the terms used herein are only for describing specific embodiments, and are not intended to limit the exemplary embodiments according to the present application. For ease of description, the sizes of the various parts shown in the drawings are not drawn according to the actual proportional relationship. The technology, methods and equipment known to ordinary technicians in the relevant field may not be discussed in detail, but in appropriate cases, the technology, methods and equipment should be regarded as part of the authorization specification. In all examples shown and discussed here, any specific value should be interpreted as merely exemplary, rather than as a limitation. Therefore, other examples of the exemplary embodiments may have different values. It should be noted that similar numbers and letters represent similar items in the following drawings, so once an item is defined in one drawing, it does not need to be further discussed in subsequent drawings.

[0043] It should be noted that the terms "first", "second", etc. in the specification and claims of the present application are used to distinguish similar objects, and are not used to describe a specific order or sequence. It should be understood that the data used in this way can be interchangeable under appropriate circumstances, so that the embodiments of the present application can be implemented in an order other than those illustrated or described here, and the objects distinguished by "first", "second", etc. are generally of one type, and the number of objects is not limited. For example, the first object can be one or more. In addition, "and / or" in the specification and claims represents at least one of the connected objects, and the character " / " generally indicates that the objects associated with each other are in an "or" relationship.

[0044] It should be noted that, in the description of the present application, the orientation or positional relationship indicated by terms such as "front, back, up, down, left, right", "lateral, vertical, perpendicular, horizontal" and "top, bottom" are usually based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present application and simplifying the description. Unless otherwise stated, these orientation words do not indicate or imply that the device or element referred to must have a specific orientation or be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the scope of protection of the present application; the orientation words "inside and outside" refer to the inside and outside relative to the contour of each component itself.

[0045] It should be noted that, in the present application, the terms "comprise", "include" or any other variant thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, an element defined by the sentence "comprises one..." does not exclude the presence of other identical elements in the process, method, article or device including the element. In addition, it should be noted that the scope of the method and device in the embodiment of the present application is not limited to performing functions in the order shown or discussed, and may also include performing functions in a substantially simultaneous manner or in reverse order according to the functions involved, for example, the described method may be performed in an order different from that described, and various steps may also be added, omitted, or combined. In addition, the features described with reference to certain examples may be combined in other examples.

[0046] Embodiment 1:

[0047] See also Figure 1 - Figure 7 As shown, this embodiment provides a granulation device for producing solid granules, comprising:

[0048] A granulation box 1, a mixing box 2 and a hydraulic cylinder 17 are fixedly installed on the top of the granulation box 1, a plurality of discharge pipes 3 are fixedly installed on the top of the mixing box 2, a valve 6 is rotatably installed in the discharge pipe 3, a charging box 4 is fixedly installed on the top of the discharge pipe 3, and a scale line 5 may be provided on one side of the charging box 4;

[0049] A rotating rod 7, the rotating rod 7 is rotatably mounted on the bottom of the inner cavity of the mixing box 2, a plurality of stirring rods 8 are fixedly mounted on the circumference of the rotating rod 7, and a scraper 9 is fixedly mounted on the rotating rod 7 and located at the bottom of the inner cavity of the mixing box 2;

[0050] Granulation chamber 14, granulation chamber 14 is opened in granulation box 1, and extrusion plate 16, drawing plate 15 and two crushing rollers 18 are arranged in order from top to bottom in granulation chamber 14, a connecting pipe 26 is fixedly installed between one side of granulation box 1 and the bottom of mixing box 2, and the output end of hydraulic cylinder 17 passes through the top of granulation box 1 and is fixed to extrusion plate 16;

[0051] A power assembly, which is located at the bottom of the mixing box 2 and is used to drive the rotating rod 7 to rotate and the two crushing rollers 18 to rotate towards each other;

[0052] The sealing assembly is located in the mixing box 2 and is used to seal the top end of the connecting pipe 26 .

[0053] Among them, through the provided charging boxes 4, different powdered medicines can be put into the charging boxes 4 from the feeding ports at the tops of the charging boxes 4 respectively, and the personnel can observe the scale lines 5 on the charging boxes 4 to ensure that the amount of the powdered medicines in the charging boxes 4 can be accurately controlled, and then the personnel can open the valves 6 respectively, at which time the powdered medicines in the charging boxes 4 will enter the inner cavity of the mixing box 2 through the discharge pipes 3 respectively, ensuring that the personnel can accurately control the various powdered medicines entering the inner cavity of the mixing box 2;

[0054] The power assembly is driven by the power assembly, which drives the rotating rod 7 to rotate and the two crushing rollers 18 to rotate in the opposite direction. The rotation of the rotating rod 7 drives a plurality of stirring rods 8 and scrapers 9 to rotate in the inner cavity of the mixing box 2. The rotation of the plurality of stirring rods 8 can fully mix the various powdered medicines in the inner cavity of the mixing box 2. When the various powdered medicines in the mixing box 2 are fully mixed, the top of the connecting pipe 26 can be opened by the sealing assembly, and then the mixed powdered medicines in the inner cavity of the mixing box 2 will flow into the connecting pipe 26. At the same time, the rotation of the scraper 9 can scrape all the mixed powdered medicines in the inner cavity of the mixing box 2 into the connecting pipe 26, and then the medicines in the connecting pipe 26 The medicine will enter the granulation chamber 14 and fall on the top of the pull-out plate 15, and then the hydraulic cylinder 17 is started. The output shaft of the hydraulic cylinder 17 drives the extrusion plate 16 to move downward. The downward movement of the extrusion plate 16 will squeeze the medicine and squeeze the powdered medicine into a cake shape. Then the personnel can pull the pull-out plate 15 out of the granulation chamber 14. At this time, the medicine cake on the pull-out plate 15 will fall onto the two crushing rollers 18. Under the crushing of the two crushing rollers 18 rotating in opposite directions, the cake-like medicine can be crushed into granules, ensuring that no liquid adhesive is added during the granulation process, reducing the subsequent drying links and costs, and also avoiding the changes in drug components that may be caused by drying in wet granulation. The process is relatively simple and the efficiency is high.

[0055] Embodiment 2:

[0056] This embodiment provides a granulation device for producing solid granules, which, in addition to the technical solutions of the above embodiments, also has the following technical features, and the power assembly includes:

[0057] A double-shaft motor 20 is fixedly installed at the bottom of the mixing box 2 and is located on one side of the connecting pipe 26. One of the output ends of the double-shaft motor 20 passes through the bottom of the mixing box 2 and is coaxially connected to the rotating rod 7. A fixing plate 24 is fixedly installed on one side of the granulation box 1 and is located below the connecting pipe 26. The other output end of the double-shaft motor 20 passes through the fixing plate 24 and is fixedly installed with a bevel gear 23. A bevel gear 1 22 is meshedly installed on one side of the bevel gear 23. A round rod 21 is fixedly installed on one end of the bevel gear 1 22, and one end of the round rod 21 passes through one side of the granulation box 1 and is coaxially connected to one of the crushing rollers 18. One end of the two crushing rollers 18 passes through one side of the charging box 4 and is fixedly installed with a first gear 19, and the two first gears 19 are meshed with each other.

[0058] Among them, the dual-axis motor 20 is started, and the two output shafts of the dual-axis motor 20 respectively drive the rotating rod 7 and the bevel gear 2 23 to rotate. The rotation of the rotating rod 7 will drive the plurality of stirring rods 8 and the scraper 9 to rotate in the inner cavity of the mixing box 2. At the same time, under the action of meshing, the rotation of the bevel gear 23 will drive the bevel gear 1 22 to rotate, and the rotation of the bevel gear 1 22 will drive the round rod 21 to rotate. The rotation of the round rod 21 will drive one of the crushing rollers 18 to rotate, and the rotation of one of the crushing rollers 18 will drive one of the first gears 19 to rotate. Under the action of meshing, the rotation of one of the first gears 19 will drive the other first gear 19 to rotate, and the rotation of the other first gear 19 will drive the other crushing roller 18 to rotate, ensuring that the two crushing rollers 18 can rotate in opposite directions. The rotation of the plurality of stirring rods 8 can fully mix the various powdered medicines in the inner cavity of the mixing box 2.

[0059] Embodiment 3:

[0060] The present embodiment provides a granulation device for the production of solid granules. In addition to the technical solutions of the above-mentioned embodiments, it also has the following technical features: one of the output shafts of the dual-axis motor 20 is rotatably connected to the mixing box 2, the other output shaft of the dual-axis motor 20 is rotatably connected to the fixed plate 24, one end of the round rod 21 is rotatably connected to the granulation box 1, and one end of the crushing roller 18 is rotatably connected to the granulation box 1.

[0061] Among them, it is ensured that one of the output shafts of the dual-axis motor 20 can rotate normally in the mixing box 2, the other output shaft of the dual-axis motor 20 can rotate normally in the fixed plate 24, one end of the round rod 21 can rotate normally in the granulation box 1, and one end of the crushing roller 18 can rotate normally in the granulation box 1.

[0062] Embodiment 4:

[0063] This embodiment provides a granulation device for producing solid granules, which, in addition to the technical solutions of the above embodiments, also has the following technical features: the sealing component includes:

[0064] The sliding groove 11 is opened in the mixing box 2 and is located at the top of the connecting pipe 26. A sealing plate 12 is slidably installed in the sliding groove 11. The sealing plate 12 is located directly above the connecting pipe 26. A pull rod 13 is fixedly installed on the other side of the sealing plate 12 and located in the sliding groove 11. One end of the pull rod 13 passes through one side of the sliding groove 11 and extends to the outside.

[0065] Among them, a person can pull the pull rod 13 hard, and the pull rod 13 will drive the sealing plate 12 to move in the sliding groove 11 until the sealing plate 12 opens the top of the connecting pipe 26, ensuring that the mixed medicine in the inner cavity of the mixing box 2 will flow into the connecting pipe 26.

[0066] Embodiment 5:

[0067] This embodiment provides a granulation device for producing solid granules. In addition to the technical solutions of the above embodiments, it also has the following technical features: the pull rod 13 is slidably connected to the sliding groove 11 and the mixing box 2.

[0068] Here, it is ensured that the pull rod 13 can slide normally in the sliding groove 11 and the mixing box 2 .

[0069] Embodiment 6:

[0070] The present embodiment provides a granulation device for the production of solid granules. In addition to the technical solutions of the above-mentioned embodiments, it also has the following technical features: a collecting box 25 is installed in the granulation box 1 and is located below the two crushing rollers 18, the pulling plate 15 is plugged into the granulation chamber 14, the extrusion plate 16 is slidably connected to the granulation chamber 14, and the crushing rollers 18 are rotatably connected to the granulation chamber 14.

[0071] Among them, under the opposite rotation and crushing of the two crushing rollers 18, the cake-like medicine can be broken into granules, and finally the granular medicine will fall into the collecting box 25, ensuring that it is convenient for personnel to collect, ensuring that the extrusion plate 16 can be inserted into the granulation chamber 14, ensuring that the extrusion plate 16 can slide normally in the granulation chamber 14, and ensuring that the crushing rollers 18 can rotate normally in the granulation chamber 14.

[0072] Embodiment 7:

[0073] The present embodiment provides a granulation device for the production of solid granules. In addition to the technical solutions of the above-mentioned embodiments, it also has the following technical features: the two ends of the connecting pipe 26 are respectively connected to the granulation chamber 14 and the inner cavity of the mixing box 2, and the two ends of the discharge pipe 3 are respectively connected to the inner cavity of the charging box 4 and the inner cavity of the mixing box 2.

[0074] Among them, it is ensured that the medicine in the inner cavity of the mixing box 2 can enter the granulation cavity 14 through the connecting pipe 26, and it is ensured that the medicine in the charging box 4 can enter the inner cavity of the mixing box 2 through the discharge pipe 3.

[0075] Embodiment 8:

[0076] This embodiment provides a granulation device for the production of solid granules. In addition to the technical solutions of the above embodiments, it also has the following technical features: the bottom end of the connecting pipe 26 is located between the extrusion plate 16 and the pulling plate 15, and the output shaft of the hydraulic cylinder 17 is slidably connected to the granulation box 1.

[0077] The structural stability of the connecting pipe 26 is ensured to ensure that the output shaft of the hydraulic cylinder 17 can slide normally in the granulation box 1 .

[0078] It is worth noting that the pull-out plate 15 is a steel plate with a thickness of 3-5 cm, which ensures that the pull-out plate 15 will not be deformed or damaged when being squeezed by the squeezing plate 16;

[0079] It is worth adding that the charging box 4 is made of a transparent material, so that personnel can observe the amount of powdered medicine in the charging box 4 through the charging box 4 .

[0080] Working principle: When using this device, the personnel first put different powdered medicines into several charging boxes 4 from the feeding ports on the tops of several charging boxes 4, and at the same time, the personnel can observe the scale lines 5 on the charging boxes 4 to ensure that the amount of powdered medicines in the charging boxes 4 can be accurately controlled. Then the personnel can open several valves 6 respectively. At this time, the powdered medicines in the several charging boxes 4 will enter the inner cavity of the mixing box 2 through several discharge pipes 3 respectively, ensuring that the personnel can accurately control the various powdered medicines entering the inner cavity of the mixing box 2. Then the personnel starts the dual-axis motor 20, and the two output shafts of the dual-axis motor 20 respectively drive the rotating rod 7 and the bevel gear 2 23 to rotate, and at the same time fix The plate 24 can ensure the stability of the output shaft of the dual-axis motor 20. The rotation of the rotating rod 7 will drive the plurality of stirring rods 8 and the scraper 9 to rotate in the inner cavity of the stirring box 2. At the same time, under the action of meshing, the rotation of the bevel gear 23 will drive the bevel gear 1 22 to rotate, and the rotation of the bevel gear 1 22 will drive the round rod 21 to rotate. The rotation of the round rod 21 will drive one of the crushing rollers 18 to rotate. The rotation of one of the crushing rollers 18 will drive one of the first gears 19 to rotate. Under the action of meshing, the rotation of one of the first gears 19 will drive the other first gear 19 to rotate, and the rotation of the other first gear 19 will drive the other crushing roller 18 to rotate, ensuring that the two crushing rollers 18 are rotated. The crushing rollers 18 can rotate in opposite directions, and the rotation of the plurality of stirring rods 8 can fully mix the various powdered medicines in the inner cavity of the stirring box 2. When the various powdered medicines in the stirring box 2 are fully mixed, the personnel can pull the pull rod 13 with force, and the pull rod 13 will drive the sealing plate 12 to move in the sliding groove 11 until the sealing plate 12 opens the top of the connecting pipe 26, and then the powdered medicine mixed in the inner cavity of the stirring box 2 will flow into the connecting pipe 26. At the same time, the scraper 9 can rotate to scrape all the mixed powdered medicines in the inner cavity of the stirring box 2 into the connecting pipe 26, and then the medicine in the connecting pipe 26 will enter the granulation chamber 14 and fall on the top of the pull-out plate 15, and then start The hydraulic cylinder 17, the output shaft of the hydraulic cylinder 17 drives the extrusion plate 16 to move downward, the extrusion plate 16 moves downward to squeeze the medicine, and squeezes the powdered medicine into a cake shape, and then the personnel can pull out the pull-out plate 15 from the granulation chamber 14, at this time the medicine cake on the pull-out plate 15 will fall onto the two crushing rollers 18, under the crushing of the two crushing rollers 18 rotating in opposite directions, the cake-like medicine can be crushed into granules, and finally the granular medicine will fall into the collecting box 25, ensuring that no liquid adhesive is added during the granulation process, reducing the subsequent drying links and costs, and also avoiding the changes in drug components that may be caused by drying in wet granulation, the process is relatively simple and the efficiency is high.

[0081] The embodiments of the present application are described above in conjunction with the accompanying drawings. In the absence of conflict, the embodiments in the present application and the features in the embodiments can be combined with each other. The present application is not limited to the above-mentioned specific implementation methods. The above-mentioned specific implementation methods are merely illustrative and not restrictive. Under the guidance of the present application, ordinary technicians in this field can also make many forms without departing from the purpose of the present application and the scope of protection of the claims, all of which are within the protection of the present application.

Claims

1. A granulation device for the production of solid granules, characterized in that: include: A granulation box (1), a mixing box (2) and a hydraulic cylinder (17) are fixedly mounted on the top of the granulation box (1), a plurality of discharge pipes (3) are fixedly mounted on the top of the mixing box (2), a valve (6) is rotatably mounted inside the discharge pipe (3), a charging box (4) is fixedly mounted on the top of the discharge pipe (3), and a scale line (5) may be provided on one side of the charging box (4); A rotating rod (7), the rotating rod (7) being rotatably mounted on the bottom of the inner cavity of the mixing box (2), a plurality of mixing rods (8) being fixedly mounted on the circumference of the rotating rod (7), and a scraper (9) being fixedly mounted on the rotating rod (7) and located at the bottom of the inner cavity of the mixing box (2); A granulation chamber (14), wherein the granulation chamber (14) is opened in a granulation box (1), wherein an extrusion plate (16), a pull plate (15) and two crushing rollers (18) are sequentially arranged in the granulation chamber (14) from top to bottom, a connecting pipe (26) is fixedly installed between one side of the granulation box (1) and the bottom of the mixing box (2), and an output end of the hydraulic cylinder (17) passes through the top of the granulation box (1) and is fixed to the extrusion plate (16); A power assembly, the power assembly is located at the bottom of the mixing box (2) and is used to drive the rotating rod (7) to rotate and the two crushing rollers (18) to rotate towards each other; A sealing component is located in the mixing box (2) and is used to seal the top end of the connecting pipe (26).

2. A granulation equipment for solid granule production according to claim 1, characterized in that: The power assembly comprises: A double-shaft motor (20), the double-shaft motor (20) is fixedly mounted at the bottom of the mixing box (2) and located on one side of the connecting pipe (26), one of the output ends of the double-shaft motor (20) passes through the bottom of the mixing box (2) and is coaxially connected to the rotating rod (7), a fixing plate (24) is fixedly mounted on one side of the granulating box (1) and located below the connecting pipe (26), the other output end of the double-shaft motor (20) passes through the fixing plate (24) and is fixedly mounted with a second bevel gear (23), one side of the second bevel gear (23) is meshedly mounted with a first bevel gear (22), one end of the first bevel gear (22) is fixedly mounted with a round rod (21), one end of the round rod (21) passes through one side of the granulating box (1) and is coaxially connected to one of the crushing rollers (18), one end of each of the two crushing rollers (18) passes through one side of the charging box (4) and is fixedly mounted with a first gear (19), and the two first gears (19) are meshed with each other.

3. A granulation equipment for solid granule production according to claim 2, characterized in that: One of the output shafts of the dual-shaft motor (20) is rotationally connected to the stirring box (2), the other output shaft of the dual-shaft motor (20) is rotationally connected to the fixed plate (24), one end of the round rod (21) is rotationally connected to the granulation box (1), and one end of the crushing roller (18) is rotationally connected to the granulation box (1).

4. A granulation equipment for solid granule production according to claim 1, characterized in that: The sealing assembly comprises: A sliding groove (11), wherein the sliding groove (11) is opened in the mixing box (2) and is located at the top end of the connecting pipe (26), a sealing plate (12) is slidably installed in the sliding groove (11), and the sealing plate (12) is located directly above the connecting pipe (26), and a pull rod (13) is fixedly installed on the other side of the sealing plate (12) and located in the sliding groove (11), and one end of the pull rod (13) passes through one side of the sliding groove (11) and extends to the outside.

5. A granulation device for producing solid granules according to claim 4, characterized in that: The pull rod (13) is slidably connected to the sliding groove (11) and the mixing box (2).

6. A granulation equipment for solid granule production according to claim 1, characterized in that: A collecting box (25) is installed in the granulation box (1) and is located below the two crushing rollers (18). The pulling plate (15) is plugged into and matched with the granulation chamber (14). The squeezing plate (16) is slidably connected to the granulation chamber (14). The crushing rollers (18) are rotatably connected to the granulation chamber (14).

7. A granulation equipment for solid granule production according to claim 1, characterized in that: The two ends of the connecting pipe (26) are respectively connected to the granulation chamber (14) and the inner cavity of the stirring box (2), and the two ends of the discharge pipe (3) are respectively connected to the inner cavity of the charging box (4) and the inner cavity of the stirring box (2).

8. A granulation equipment for solid granule production according to claim 1, characterized in that: The bottom end of the connecting pipe (26) is located between the extrusion plate (16) and the pulling plate (15), and the output shaft of the hydraulic cylinder (17) is slidably connected to the granulation box (1).

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