Depressed animal movement behavior analysis device

Abstract

The utility model discloses a motion behavior analysis device for a depression animal. The motion behavior analysis device comprises a box body for placing the animal, the movable clamping plate penetrates through the box body and is rotationally connected with the side wall of the box body; a clamping block A is arranged at the free end of the movable clamping plate; the fixed clamping plate is horizontally fixed in the box body, and the fixed clamping plate and the movable clamping plate are symmetrically arranged; a clamping block B is arranged at the free end of the fixed clamping plate; the clamping block A is in sliding fit with the clamping block B and is used for clamping the tail of the depression animal.

Description

Technical Field

[0001] The utility model relates to the technical field of animal husbandry tools, in particular to a device for analyzing movement behavior of depressed animals. Background Art

[0002] In modern society, when studying drugs to treat depression, it is necessary to use animal models such as mice. The depressive-like behaviors produced by these animal models reflect their degree of depression. Among them, the tail suspension test is the most commonly used experimental paradigm for animal depressive-like behavior. After 2000, researchers began to use this experimental model extensively and found that injecting antidepressant drugs into mice with depressive-like behavior could shorten the immobility time of mice in the tail suspension test.

[0003] The experiment requires that mice be suspended upside down by their tails in a box 10 cm above the ground for 5-8 minutes, so that the mice cannot touch the ground. The time for the mice to give up struggling and remain motionless is recorded by monitoring. The immobility of mice in the tail suspension test and forced swimming test is regarded by researchers as a desperate behavior of experimental animals who do not want to make any effort to escape.

[0004] However, in the existing tail suspension test, the process of hanging the mouse will stimulate it, causing the mouse to struggle violently. Furthermore, when fixing the mouse's tail, the clamps fixed at the position of the mouse's tail fixing point cannot tightly fix the mouse. At the same time, if the position of the tail fixing point is close to the mouse's body, the mouse will crawl along the tail and lie on the tail, making it impossible to be accurately hung and difficult to enter a motionless state, requiring the test to be restarted, resulting in a waste of test time.

[0005] Therefore, it is absolutely necessary to propose a device for analyzing the movement behavior of depressed animals that is suitable for the tail suspension test. Summary of the invention

[0006] In view of the above technical problems, the utility model provides a depressed animal movement behavior analysis device, which solves the problem that mice are easily dropped due to loose clamping when hanging by utilizing a clamping block with a clamping force gradually increased with gravity.

[0007] In order to achieve the above technical purpose, the utility model adopts the following technical means:

[0008] A device for analyzing the movement behavior of depressed animals, comprising a box for placing the animals; the interior of the box is provided with:

[0009] A movable splint passes through the box body and is rotatably connected to its side wall; a clamping block A is provided at the free end of the movable splint;

[0010] A fixed clamping plate is horizontally fixed inside the box body and is symmetrically arranged with the movable clamping plate; a clamping block B is arranged at the free end of the fixed clamping plate;

[0011] The clamping block A and the clamping block B are slidably matched to clamp the tail of the depressed animal under the action of gravity.

[0012] The clamping block A is provided with a groove; the clamping block B is provided with a convex block sliding in the groove; the shape of the convex block matches the shape of the groove.

[0013] The protrusion is an arc structure that bears force more evenly.

[0014] It also includes: a limiting mechanism disposed below the fixed clamping plate, which includes a hollow sleeve and a sliding rod;

[0015] The hollow sleeve symmetrically penetrates the two side walls of the box body;

[0016] The slide bar is slidably connected to the inside of the hollow sleeve; the end of the slide bar in the box body is provided with a clamping claw for clamping the waist of the depressed animal.

[0017] The inner end of the slide bar is provided with a supporting plate; the supporting plate is used for receiving excrement of depressed animals.

[0018] Also included: a monitoring mechanism disposed above the fixed clamping plate, comprising a T-shaped rod and a video recorder;

[0019] The vertical rod part of the T-shaped rod passes through the top of the box body and is rotatably connected thereto; the horizontal rod part of the T-shaped rod is provided with a video recorder for recording the movement behavior of the depressed animal.

[0020] The T-shaped rod and the video recorder are connected via a connecting piece; the connecting piece is used to adjust the orientation angle of the video recorder.

[0021] The connecting piece adopts a hard threaded pipe.

[0022] It also includes a driving mechanism arranged on the side of the box body; the driving mechanism is used to drive the T-shaped rod to rotate; the driving mechanism includes a driving motor, a first gear, a second gear and a gear ring;

[0023] The driving motor is fixed inside the motor box on one side of the box body, and its output end is connected to the first gear;

[0024] The second gear placed vertically is rotatably mounted on the side wall of the box body and meshes with the first gear;

[0025] The crossbar of the T-shaped bar is fixed inside the gear ring, and the gear ring is meshed with the second gear.

[0026] The inner side wall of the motor box is provided with sound insulation cotton.

[0027] Beneficial effects:

[0028] First, the utility model adopts the matching arrangement between the movable splint, the fixed splint and the clamping block. After the mouse's tail is placed in the groove, the movable splint is rotated clockwise, and the mouse's tail is squeezed with the protrusion to limit the position of the mouse's tail. At this time, due to the factor of gravity, the more the mouse struggles, the tighter the matching between the protrusion and the groove, and the tighter the mouse's tail is clamped; thus, the mouse is prevented from falling due to struggling, and the stability and reliability of the test are improved.

[0029] Second, the utility model uses the matching arrangement between the hollow slider and the slide bar, and the two slide bars limit the body of the mouse, preventing the mouse from climbing along the tail, thereby ensuring the mouse is in a suspended state; thereby, the stability and reliability of the test are improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] Figure 1 This is a structural diagram of the behavior analysis device of the utility model;

[0031] Figure 2 for Figure 1 A schematic diagram of the enlarged structure at A in the middle;

[0032] Figure 3 This is a schematic diagram of the structure of the clamping block A and the clamping block B of the behavior analysis device of the utility model.

[0033] In the figure: 1, box body; 2, limiting mechanism; 201, hollow slider; 202, slide rod; 203, support plate; 3, movable splint; 4, second gear; 5, gear ring; 6, T-bar; 7, video recorder; 8, connecting piece; 9, motor; 10, first gear; 11, motor box; 12, fixed splint; 13, clamping block; 1301, block; 1302, groove; 1303, protrusion. DETAILED DESCRIPTION

[0034] In order to better understand the above technical solution, the above technical solution will be described in detail below in conjunction with the accompanying drawings and specific implementation methods.

[0035] The structural diagram of the behavior analysis device of the utility model is as follows Figure 1-3 shown.

[0036] See also Figure 1-3A device for analyzing movement behavior of depressed animals includes a box body 1, an inner wall of the box body 1 is movably connected with a movable splint 3, and the inner wall on the opposite side of the box body 1 is also fixedly connected with a fixed splint 12; the inner ends of the movable splint 3 and the fixed splint 12 are fixedly connected with a clamping block 13; specifically, the free end of the movable splint 3 is provided with a clamping block A; the free end of the fixed splint 12 is provided with a clamping block B; the clamping block A and the clamping block B are slidably matched to clamp the tail of the depressed animal.

[0037] The clamping block 13 includes two blocks 1301, a clamping block A and a clamping block B, wherein a groove 1302 is provided on the side of the clamping block A, and a protrusion 1303 is provided on the side of the clamping block B; wherein the protrusion 1303 and the groove 1302 are of the same size. When clamping, the mouse tail is placed in the groove 1302, and the protrusion 1303 is used to squeeze the mouse tail, and the position of the mouse tail is limited, which further increases the stability of the mouse and prevents the mouse from falling off. Specifically, the protrusion can be a circular arc structure with more uniform force.

[0038] A limiting mechanism 2 is also provided inside the box body 1, and the limiting mechanism 2 includes a hollow slider 201 fixedly connected to the two outer sides of the box body 1, and a slide rod 202 is slidably connected inside the hollow slider 201. The end of the slide rod 202 inside the box body 1 is provided with a claw for clamping the waist of the depressed animal.

[0039] Through the coordination among the box body 1, the limiting mechanism 2, the hollow slider 201, the slide bar 202, the movable splint 3, the fixed splint 12 and the clamping block 13, when hanging a mouse, first rotate the movable splint 3 counterclockwise, and then determine the clamping position of the mouse's tail. The position of the fixed point of the mouse's tail is as far away from the mouse's body as possible to prevent the mouse from crawling along the tail and lying on the tail. The mouse's tail is placed in the groove 1302 at the end of the fixed splint 12, and then the movable splint 3 is rotated clockwise to make the movable splint 3 and the clamping block 13 at the end of the fixed splint 12 close to each other, and the protrusion 1303 is used to squeeze the mouse's tail to limit the position of the mouse's tail, thereby further increasing the stability of the mouse, preventing the mouse from falling off, and avoiding restarting the detection.

[0040] The slide bar 202 slides in the hollow slider 201, and the two slide bars 202 are used to limit the body of the mouse to prevent the mouse from climbing along the tail, thereby ensuring that the mouse is in a suspended state.

[0041] Furthermore, the inner end of the slide bar 202 is fixedly connected with a support plate 203. The mouse will be stimulated during the hanging process and produce a lot of excrement after the stress. The support plate 203 can be used to receive the excrement.

[0042] The top of the box body 1 is rotatably connected to a T-bar 6, and the lower surface of the T-bar 6 is fixedly connected to a connecting piece 8, which is a hard threaded tube. The hard threaded tube can be bent manually to facilitate adjusting the direction of the video recorder 7. The bottom end of the connecting piece 8 is rotatably connected to the video recorder 7. The video recorder 7 on the connecting piece 8 is rotated to aim the video recorder 7 at the mouse. The T-bar 6 is manually moved to rotate the T-bar 6. The rotation of the T-bar 6 drives the video recorder 7 to rotate through the connecting piece 8, so that the video recorder 7 can be rotated in the horizontal direction, which is easy to use.

[0043] A driving mechanism is provided on the side of the box body 1, and the driving mechanism includes a motor 9 fixedly connected to the outer side surface of the box body 1, the output end of the motor 9 is fixedly connected to the first gear 10, the side wall of the box body 1 is rotatably connected to the second gear 4 meshing with the first gear 10, the end of the T-bar 6 is fixedly connected to the gear ring 5 meshing with the second gear 4, the outer side surface of the box body 1 is fixedly connected to the motor box 11, the motor 9 is fixedly connected to the inner side wall of the motor box 11, and the inner side wall of the motor box 11 is provided with sound insulation cotton, the motor 9 drives the first gear 10 to rotate, the first gear 10 drives the gear ring 5 through the second gear 4, the gear ring 5 drives the T-bar 6 to rotate, thereby realizing the automatic rotation of the video recorder 7, and the sound insulation cotton can block part of the sound of the motor 9 from entering the box body 1, thereby reducing the impact of the motor 9 on mice.

[0044] Working principle:

[0045] In the utility model, the mouse tail is placed in the groove 1302 and squeezed by the protrusion 1303 to limit the position of the mouse tail, further increasing the stability of the mouse and preventing the mouse from falling off; the slide bar 202 slides in the hollow slider 201, and the two slide bars 202 are used to limit the body of the mouse to prevent the mouse from climbing along the tail, thereby ensuring that the mouse is in a suspended state.

[0046] In the process of hanging the mouse, the mouse will be stimulated and produce a lot of excrement, and the support plate 203 can be used to receive the excrement.

[0047] Rotate the video recorder 7 on the connecting piece 8 to aim the video recorder 7 at the mouse, manually turn the T-bar 6 to rotate the T-bar 6, and the rotation of the T-bar 6 drives the video recorder 7 to rotate through the connecting piece 8, so that the video recorder 7 can be rotated in the horizontal direction. It is easy to use. The motor 9 drives the first gear 10 to rotate, and the first gear 10 drives the gear ring 5 through the second gear 4. The gear ring 5 drives the T-bar 6 to rotate, thereby realizing the automatic rotation of the video recorder 7. The sound insulation cotton can block part of the sound of the motor 9 from entering the box 1, thereby reducing the impact of the motor 9 on the mouse.

Claims

1. A device for analyzing the movement behavior of depressed animals, comprising a box for placing animals; characterized in that: The interior of the box is provided with: A movable splint passes through the box body and is rotatably connected to its side wall; a clamping block A is provided at the free end of the movable splint; A fixed clamping plate is horizontally fixed inside the box body and is symmetrically arranged with the movable clamping plate; a clamping block B is arranged at the free end of the fixed clamping plate; The clamping block A and the clamping block B are slidably matched to clamp the tail of the depressed animal under the action of gravity.

2. The depressed animal movement behavior analysis device according to claim 1, characterized in that: The clamping block A is provided with a groove; the clamping block B is provided with a convex block sliding in the groove; the shape of the convex block matches that of the groove.

3. The depressed animal movement behavior analysis device according to claim 2, characterized in that: The protrusion is an arc structure that bears force more evenly.

4. The depressed animal movement behavior analysis device according to claim 1, characterized in that: Also includes: A limiting mechanism disposed below the fixed clamping plate, comprising a hollow sleeve and a sliding rod; The hollow sleeve symmetrically penetrates the two side walls of the box body; The slide bar is slidably connected to the inside of the hollow sleeve; the end of the slide bar in the box body is provided with a clamping claw for clamping the waist of the depressed animal.

5. The depressed animal movement behavior analysis device according to claim 4, characterized in that: The inner end of the slide bar is provided with a supporting plate; the supporting plate is used for receiving excrement of depressed animals.

6. The depressed animal movement behavior analysis device according to claim 1, characterized in that: Also includes: A monitoring mechanism disposed above the fixed clamping plate, comprising a T-shaped rod and a video recorder; The vertical rod part of the T-shaped rod passes through the top of the box body and is rotatably connected thereto; the horizontal rod part of the T-shaped rod is provided with a video recorder for recording the movement behavior of the depressed animal.

7. The depressed animal movement behavior analysis device according to claim 6, characterized in that: The T-shaped rod and the video recorder are connected via a connecting piece; the connecting piece is used to adjust the orientation angle of the video recorder.

8. The depressed animal movement behavior analysis device according to claim 7, characterized in that: The connecting piece adopts a hard threaded pipe.

9. The depressed animal movement behavior analysis device according to claim 6, characterized in that: It also includes a driving mechanism arranged on the side of the box body; the driving mechanism is used to drive the T-shaped rod to rotate; the driving mechanism includes a driving motor, a first gear, a second gear and a gear ring; The driving motor is fixed inside the motor box on one side of the box body, and its output end is connected to the first gear; The second gear placed vertically is rotatably mounted on the side wall of the box body and meshes with the first gear; The crossbar of the T-shaped bar is fixed inside the gear ring, and the gear ring is meshed with the second gear.

10. The depressed animal movement behavior analysis device according to claim 9, characterized in that: The inner side wall of the motor box is provided with sound insulation cotton.

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